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| 1 | Delayed hepatocarcinogenesis through antiangiogenic intervention in the nuclear factor-kappa B activation pathway in rats显示文摘BACKGROUND:The active form of nuclear factor-kappa B(NF- κB)is involved in the initiation,generation,and development of hepatocellular carcinoma(HCC),and is up-regulated in inflammation-associated malignancies.We investigated the dynamic expression of NF-κB and its influences on the occurrence of HCC through antiangiogenic(thalidomide) intervention in NF-κB activation. METHODS:Hepatoma models were induced with 2-fluorenyl- acetamide(2-FAA,0.05%)in male Sprague-Dawley rats,and thalidomide(100 mg/kg body weight)was administered intragastrically to intervene in NF-κB activation.The pathological changes in the liver of sacrificed rats were assessed after hematoxylin and eosin staining.NF-κB mRNA was amplified by RT-nested PCR.The alterations of NF-κB and vascular endothelial growth factor(VEGF)expression were analyzed by enzyme-linked immunosorbent assay,immunohistochemistry,and Western blotting. RESULTS:Rat hepatocytes showed denatured,precancerous,and cancerous stages in hepatocarcinogenesis,with an increasing tendency of hepatic NF-κB,NF-κB mRNA,and VEGF expression,and their values in the HCC group were higher than those in controls(P<0.001).In the thalidomide- treated group,the morphologic changes generated only punctiform denaturation and necrosis at the early or middle stages,and nodular hyperplasia or a little atypical hyperplasia at the final stages,with the expression of NF-κB (χ2=9.93,P<0.001)and VEGF(χ2=8.024,P<0.001)lower than that in the 2-FAA group. CONCLUSION:NF-κB is overexpressed in hepatocarcinogenesis and antiangiogenic treatment down-regulates the expression of NF-κB and VEGF,and delays the occurrence of HCC. | Dong, Zhi-Zhen Yao, Deng-Fu Wu, Wei Yao, Min Yu, Hong-Bo Shen, Jun-Jun Qiu, Li-Wei Yao, Ning-Hua Sai, Wen-Li Yang, Jun-Ling | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，2： | 31 |
| 2 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 3 | Oncostatin M-induced cardiomyocyte dedifferentiation regulates the progression of diabetic cardiomyopathy through B-Raf/Mek/Erk signaling pathway显示文摘oncostatin M (OSM ) 能在 vivo 并且在 vitro 开始 cardiomyocyte dedifferentiation,这被报导了。导致 OSM 的 cardiomyocyte dedifferentiation 可能是为糖尿病的心肌症(DCM ) 的处理的一个新目标。这研究被设计在 cardiomyocyte dedifferentiation 和 DCM 的前进决定 OSM 的角色。一个老鼠 DCM 模型被建立在 vivo 评估 OSM 的效果。Echocardiography 被使用决定心脏的功能。染色的天狼星红被用来检测纤维变性区域。传播电子显微镜学被用来评估线粒体缺陷。实时聚合酶链反应和西方的污点分析被执行检测相对 mRNA 表情和 cardiomyocyte dedifferentiation 相关的蛋白质表情分别地。OSM 处理导致了类似的损害心脏的功能和心脏的超微结构缺陷到在 DCM 鼠标检测的那些。cardiomyocyte 的 dedifferentiation 标记的表达式(Runx1,和 -SM-actin) 与在控制组的那些相比在对待 OSM 的鼠标是起来调整的。为了推进,表明 OSM 的重要角色, OSM 受体大美人(O ko ) 老鼠被使用。在 O ko 老鼠, c 工具包的 cardiomyocytes dedifferentiation 标记, Runx1,和 atrial natriuretic 肽是下面调整的,与稀释 DCM 损害和废除 OSM/B-Raf/Mek/Erk 发信号小径。在结论,导致 OSM 的 cardiomyocyte dedifferentiation 在 DCM 的前进起一个关键作用。导致 OSM 的 cardiomyocyte dedifferentiation 的机制与通过 OSM 受体 O 表明小径的 B-Raf/Mek/Erk 被联系。 | Xiaotian Zhang Sai Ma Ran Zhang Shuang Li Di Zhu Dong Han Xiuiuan Li Congye Li Wei Yan Dongdong Sun Bin Xu Yabin Wang Feng Cao | 2016 | Acta Biochimica et Biophysica Sinica2016，48，3： | 7 |
| 4 | Protective effects of curcumin against human immunodeficiency virus 1 gp120 V3 loop-induced neuronal injury in rats显示文摘Curcumin improves the learning and memory deficits in rats induced by the gp120 V3 loop. The present study cultured rat hippocampal neurons with 1 nM gp120 V3 loop and 1 μM curcumin for 24 hours. The results showed that curcumin inhibited the gp120 V3 loop-induced mitochondrial membrane potential decrease, reduced the mRNA expression of the pro-apoptotic gene caspase-3, and attenuated hippocampal neuronal injury. | Zheng Gong Lijuan Yang Hongmei Tang Rui Pan Sai Xie Luyan Guo Junbin Wang Qinyin Deng Guoyin Xiong Yanyan Xing Jun Dong | 2012 | Neural Regeneration Research2012，7，3： | 5 |
| 5 | Emerging frontier technologies for food safety analysis and risk assessment显示文摘Access to security and safe food is a basic human necessity and essential for a sustainable world. To perform hi-end food safety analysis and risk assessment with state of the art technologies is of utmost importance thereof. With applications as exemplified by microfluidic immunoassay,aptasensor,direct analysis in real time,high resolution mass spectrometry,benchmark dose and chemical specific adjustment factor,this review presents frontier food safety analysis and risk assessment technologies,from which both food quality and public health will benefit undoubtedly in a foreseeable future. | DONG Yi-yang LIU Jia-hui WANG Sai CHEN Qi-long GUO Tian-yang ZHANG Li-ya JIN Yong SU Hai-jia TAN Tian-wei | 2015 | Journal of Integrative Agriculture2015，14，11： | 4 |
| 6 | Up-conversion fluorescence biosensor for sensitive detection of CA-125 tumor markers显示文摘Sensitive and specific bioassays of tumor markers are critical for early cancer detection and treatment.In recent years,lanthanide(Ln3+)doped upconversion nanoparticles(UCNPs)have attracted wide attentions in tumor markers detectio n.Herein,we co mbined NaYF4:Yb,Tm and silver nanoparticles,serving as energy donor and receptor,respectively,to form an up-conversion fluorescence based inhibitory tumor marker biosensor system.The tumor marker CA-125 molecules are labeled with silver NPs,and the energy transfer fluorescent signal can be detected between the UCNPs and the silver NP receptors.The biosensor shows good stability,high sensitivity and selectivity in the tumor marker concentration range from 5 to 100 ng/mL,as well as a detection limit of 120 pg/mL.Due to the advantage of ease of fabrication and operation,low cost and high information capacity,this technology holds great potential for the clinical applications. | Jingshi Liu Sai Xu Liheng Sun Songtao Hu Jiao Sun Min Liu Cui Ma Haipeng Liu Ziqing Wang Ying Yang Biao Dong Decheng Hong | 2019 | Journal of Rare Earths2019，37，9： | 3 |
| 7 | Cardiotrophin-1 promotes cardiomyocyte differentiation from mouse induced pluripotent stem cells via JAK2/STAT3/Pim-1 signaling pathway显示文摘BackgroundThe 导致了 pluripotent 干细胞(iPSC ) 在心肌的梗塞(MI ) 的细胞的治疗显示出大潜力,当它的申请被 cardiomyocyte 区别的低效率妨碍时。现在的学习被设计从老鼠在 cardiomyocyte 区别上调查 cardiotrophin-1 ( CT-1 )的效果导致的 pluripotent 干细胞( miPSCs )和内在的机制 involved.MethodsThe 为从 miPSCs 的 cardiomyocyte 区别的最佳的治疗状况与理想的集中( 10 ng/mL )和持续时间被建立(从到白天的白天 3 14 ) CT-1 管理。说明了胚胎的 cardiogenesis 的心脏的特定的基因的起来调整的表示被量的 RT-PCR 观察。 α 的提高的数量;肌浆球蛋白重链( α ;-MHC)和心脏的 troponin 我( cTn 我)积极房间被 immunofluorescence 在显微镜的分析揭示了的 CT-1 group.ResultsTransmission 电子染色和流动 cytometry 分析检测与 CT-1 对待的房间更好出现了,这组织了 sacromeric 结构和更多线粒体,它是成熟 cardiomyocytes 的词法特征。当与控制 group.ConclusionsThese 相比调查结果建议 CT-1 能提高 cardiomyocyte 区别以及导致的 pluripotent 干细胞导出的老鼠的成熟,西方的污点证明 CT-1 经由 JAK2/STAT3/Pim-1 小径部分从 miPSCs 支持 cardiomyocyte 区别由调整 JAK2/STAT3/Pim-1signaling 的 cardiomyocytes 小径。 | Tong LIU Ran ZHANG Tao GUO Sai MA Dong HAN Xiu-Juan LI Yan JIN Miao-Miao FAN Ya-Bin WANG Yun-Dai CHEN Feng CAO | 2015 | Journal of Geriatric Cardiology2015，12，6： | 2 |
| 8 | Outcome of Cox Maze procedure concomitant with mitral valve operation in treatment of atrial fibrillation显示文摘Atrial 纤维性颤动(AF ) 在有长期的僧帽形的阀门疾病和显著地扩大的左中庭的病人是相当普通的。这些病人很少自发地回到湾穴节奏,甚至在成功的僧帽形的阀门操作以后。迷宫过程,由 Coxand 伙伴发展了,在经历一个僧帽形的阀门手术的病人被使用了。正常湾穴节奏并且在在如此的病人的伊朗的银币收缩的恢复被一些组报导了。这研究将回顾地总结为在中国与风湿病的僧帽形的阀门疾病联系的 AF 的治疗经历了艇长迷宫过程的一组病人。 | ZHANG Sai CHEN Ru-kun DONG Ai-qiang WANG Yong-qin CHEN Suo-cheng LI Zhi-jun | 2006 | Chinese Medical Journal2006，，16： | 2 |
| 9 | State of the art:Lateral flow assay(LFA) biosensor for on-site rapid detection显示文摘Recently, lateral flow assay(LFA) has attracted researchers' attention because of its considerable advantages of superior portability, rapid detection, cost-effectiveness and ease of use. This review provides a brief overview of latest researches of LFA, including the practical use of LFA in both qualitative and quantitative analysis in different areas. Though bio-recognition molecules in the LFA used to be antibodies, a new kind of recognition element called aptamer, showing significant advantages, is developed rapidly in recent years. The highly specific recognition of aptamers/antibodies and targets are combined with the excellent properties of a dry-reagent strip biosensor that enables efficiently detection in point-of-care applications. Herein, we compared the aptamers with antibodies, summarized the principle of LFAs, and three main elements for the LFAs(recognition molecule, signal transduction element, the targets). Additionally, we summarized different optimal experimental conditions in the recent LFA-related studies to give detailed overview of the LFA development. We hope the review can give a general guide for the development of LFAs. | Shuai Zhao Sai Wang Shan Zhang Jiahui Liu Yiyang Dong | 2018 | Chinese Chemical Letters2018，29，11： | 2 |
| 10 | Influencing factors and evaluation application of regional crustal stability in the Bohai Strait显示文摘Due to the extremely complex geological conditions in the Bohai Strait, active faults is very developed and earthquake activity occurs frequently. It is of great importance to evaluate the regional crustal stability for the planning and construction of the Trans-straits Passage. In this study, the authors carry out the evaluation by means of buffer analysis, topology analysis and overlay analysis based on ArcGIS software. The evaluation mainly analyzed six assessment factors of Bohai Strait including neotectonic activity, active faults distribution, seismicity, tectonic stress fields, Bouguer gravity anomaly and geological disasters. In brief, the crustal stability of the eastern North Yellow Sea Basin is best, while that of the Bohai Basin and southwest Bohai Strait is poor. Meanwhile, small and frequent earthquakes in the southern Strait and geological disasters developed in the northern and central Strait such as tidal ridge and shallow gas which may adversely impact on the Trans-straits Passage construction. | Sai Mei Hong-xian Chu Ling-yu Dong Zhong-hua Fang Pan-feng Li Fei-fei Zhang Rui Shan Tie-hu Zhao | 2019 | China Geology2019，2，3： | 2 |
| 11 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 12 | Surface Integrity of Ultrasonically-Assisted Milled Ti6Al4V Alloy Manufactured by Selective Laser Melting显示文摘The Ti6Al4V parts produced by the existing selective laser melting(SLM)are mainly confronted with poor surface finish and inevitable interior defects,which substantially deteriorates the mechanical properties and performances of the parts.In this regard,ultrasonically-assisted machining(UAM)technique is commonly introduced to improve the machining quality due to its merits in increasing tool life and reducing cutting force.However,most of the previous studies focus on the performance of UAM with ultrasonic vibrations applied in the tangential and feed directions,whereas few of them on the impact of ultrasonic vibration along the vertical direction.In this study,the effects of feed rate on surface integrity in ultrasonically-assisted vertical milling(UAVM)of the Ti6Al4V alloy manufactured by SLM were systemically investigated compared with the conventional machining(CM)method.The results revealed that the milling forces in UAVM showed a lower amplitude than that in CM due to the intermittent cutting style.The surface roughness values of the parts produced by UAVM were generally greater than that by CM owing to the extra sinusoidal vibration textures induced by the milling cutter.Moreover,the extra vertical ultrasonic vibration in UAVM was beneficial to suppressing machining chatter.As feed rate increased,surface microhardness and thickness of the plastic deformation zone in CM raised due to more intensive plastic deformation,while these two material properties in UAVM were reduced owing to the mitigated impact effect by the high-frequency vibration of the milling cutter.Therefore,the improved surface microhardness and reduced thickness of the subsurface deformation layer in UAVM were ascribed to the vertical high-frequency impact of the milling cutter in UAVM.In general,the results of this study provided an in-depth understanding in UAVM of Ti6Al4V parts manufactured by SLM. | Sai Guo Wei Du Qinghong Jiang Zhigang Dong Bi Zhang | 2021 | Chinese Journal of Mechanical Engineering2021，34，4： | 2 |
| 13 | New construction of hybrid and aperiodic ordered PBG cavity显示文摘The band gap of a photonic crystal (PhC) cavity intrinsically avoids HOM problems. In this paper, we present a new PBG structure based on the possible advantage of using hybrid structures and aperiodic lattices. This novel hybrid and aperiodically ordered cavity was designed for apparently higher Q-factor (more than 10300) and achieving large accelerating field gradient. The HOMs in the cavity are able to be absorbed efficiently. | ZHAO JingXiong WU CongFeng FAN Hao LI Bo DONG Sai | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 2 |
| 14 | Influence of heat stress on leaf ultrastructure, photosynthetic performance, and ascorbate peroxidase gene expression of two pear cultivars(Pyrus pyrifolia)显示文摘Plants encounter a variety of stresses in natural environments. One-year-old pot-grown trees of pear(Pyrus pyrifolia Nakai cv. Cuiguan and Wonhwang) were exposed to two heat stress regimes. Under constant short-term heat stress, chloroplasts and mitochondria were visibly damaged. Relative chlorophyll content and maximum photochemical efficiency of photosystem II were significantly decreased, which indicated that the leaf photosynthetic capability declined. Under chronic heat stress, mesophyll cell ultrastructure was not obviously damaged, but leaf photosynthetic capability was still restrained. As chronic heat stress was a simulation of the natural environment in summer, further study of the responses under this stress regime was undertaken. Ascorbate peroxidase(APX) activity was increased in ‘Cuiguan', but not in ‘Wonhwang'. Inducible expression of PpAPX genes in the cytoplasm, chloroplasts and peroxisomes was consistent with increased APX activity in ‘Cuiguan', whereas only weak induction of PpAPX genes was observed in ‘Wonhwang'. The isoenzymes cytosolic APX1(cAPX1) and stromal APX(sAPX) were confirmed to be localized in the cytoplasm and chloroplasts, respectively. | Dong-feng LIU Dong ZHANG Guo-qin LIU Sayed HUSSAIN Yuan-wen TENG | 2013 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2013，14，12： | 2 |
| 15 | Targeting of DICE1 tumor suppressor by Epstein–Barr virus‐encoded miR‐BART3* microRNA in nasopharyngeal carcinoma显示文摘 | Ting Lei Kit‐San Yuen Rui Xu Sai Wah Tsao Honglin Chen Mengfeng Li Kin‐Hang Kok Dong‐Yan Jin | 2013 | Int J Cancer2013，，1： | 1 |
| 16 | The Parkinson’s disease-related genes act in mitochondrial homeostasis显示文摘 | Yan Sai Zhongmin Zou Kaige Peng Zhaojun Dong | 2012 | Neuroscience and Biobehavioral Reviews2012，，9： | 1 |
| 17 | Phosphorylated-ERK 1/2 and neuronal degeneration induced by rotenone in the hippocampus neurons显示文摘 | Yan Sai Junfeng Chen Qiang Wu Hiu Liu Jiqing Zhao Zhaojun Dong | 2009 | Environmental Toxicology and Pharmacology2009，，3： | 1 |
| 18 | Conformational Structure-dependentMolecular Recognition of Two Aptamers for Tetracycline显示文摘 | Sai Wang Yiyang Dong | 2015 | RSC Advances2015，，06： | 1 |
| 19 | Quasi-static simulation of droplet morphologies using a smoothed particle hydrodynamics multiphase model显示文摘Numerical simulation of the morphology of a droplet deposited on a solid surface requires an efficient description of the three-phase contact line. In this study, a simple method of implementing the contact angle is proposed, combined with a robust smoothed particle hydrodynamics multiphase algorithm (Zhang 2015). The first step of the method is the creation of the virtual liquid-gas interface across the solid surface by means of dummy particles, thus the calculated surface tension near the triple point serves to automatically modulate the dynarnic contact line towards the equilibrium state. We simulate the evolution process of initially square liquid lumps on fiat and curved surfaces. The predictions of droplet profiles are in good agreement with the analytical solutions provided that the macroscopic contact angle is accurately implemented. Compared to the normal correction method, the present method is straightforward without the need to manually alter the normal vectors. This study presents a robust algorithm capable of capturing the physics of the static welling. It may hold great potentials in bio-inspired superhydrophobic surfaces, oil displacement, microfluidics, ore floatation, etc. | Xiangwei Dong Jianlin Liu Sai Liu Zengliang Li | 2019 | Acta Mechanica Sinica2019，35，1： | 1 |
| 20 | Effect of bicarbonate on CO_(2) electroreduction over cathode catalysts显示文摘CO_(2) electroreduction (CO_(2) ER) using renewable energy is ideal for mitigating the greenhouse effect and closing the carbon cycle. Bicarbonate (HCO_(3)−) is most commonly employed as the electrolyte anion because it is known to facilitate CO_(2) ER. However, its dynamics in the electric double layer remains obscure and requires more in-depth investigation. Herein, we investigate the refined reduction process of bicarbonate by employing in situ attenuated total reflectance surface-enhanced infrared absorption spectroscopy. By comparing the product distributions in Ar-saturated KCl and KHCO_(3) electrolytes, we confirmed CO production from HCO_(3)^(−) in the absence of an external CO_(2) source. Notably, in contrast to an electric compulsion, negatively charged HCO_(3)− anions were found to accumulate near the electrode surface. A reduction mechanism of HCO3− is proposed in that HCO3− is not adsorbed over a catalyst, but may be enriched near the electrode surface and converted to CO_(2) and react over Au and Cu electrodes. The dependence of the CO_(2) ER activity on the local HCO3− concentration was subsequently discovered, which was in turn dependent on the bulk HCO3− concentration and cathodic potential. In particular, the local HCO3− concentration was limited by the cathodic potential, leading to a plateau in the CO_(2) ER activity. The proposed mechanism provides insights into the interaction between the catalyst and the electrolyte in CO_(2) ER. | Wanyu Deng Tenghui Yuan Sai Chen Huimin Li Congling Hu Hao Dong Bo Wu Tuo Wang Jingkun Li Geoffrey A.Ozin Jinlong Gong | 2021 | Fundamental Research2021，1，4： | 0 |
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