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| 1 | Black tea in chemo-prevention of cancer and other human diseases显示文摘Tea is the most popular functional beverage in the world and has been gaining more and more attention for its health beneficial properties.Among common teas,black tea is consumed more than green tea and oolong tea worldwide.Numerous studies have shown the biological activities of black tea and its polyphenols that include anti-oxidant,anti-tumor,anti-inflammation and metabolic regulation.Tea polyphenols such as theaflavins and catechins are considered to be multifunctional compounds that could be effective in the prevention or treatment of various cancers,cardiovascular disease,chronic inflammation,obesity,metabolic syndrome,and neurodegenerative diseases.In this review,we summarized the up-to-date research and underlying molecular mechanisms of black tea and its polyphenols.©2013 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Min-Hsiung Pan Ching-Shu Lai Hong Wang Chih-Yu Lo Chi-Tang Ho Shiming Li | 2013 | Food Science and Human Wellness2013，2，1： | 16 |
| 2 | Hepatic encephalopathy complicated with hyponatremia and acid-base disturbance and its prognosis显示文摘Objective:To improve the diagnosis and therapeutic effect of occurrence and development of hyponatremia and disorder of acid-base balance among patients with hepatic encephalopathy(HE) by elucidating the regularity and mechanism,as well as its influence on prognosis.Methods:327 HE patients admitted to our hospital from January 1990 to June 2010 were enrolled.Meanwhile 316 patients hospitalized in the medical department of the same hospital were chosen as the control group.Patients in both groups were given the same methods to measure arterial blood gas parameters(pH value,PaCO2,[HCO3-],TCO2,BE and SaO2),blood biochemistry([Na+],[K+],[Cl-]),liver function,kidney function and blood glucose,serum sodium,and thereupon tocalculate the anion gap(AG) and the potential [HCO3-],and acid-base balance disorder.Results:Among the 327 HE patients,hyponatremia was found in 188 cases(57.4%),of whom 132 patients died(70.2%).While among the 316 patients in control group,68 presented with hyponatremia(21.5%),and 19 died(27.9%).The incidence and mortality were significantly different between the two groups(P<0.001).All the 327 patients presented with different degrees of acid-base balance disorder and 178 died(54.4%),in whom 164(50.2%) belonged to simple acid-base balance disorder and 74(45.1%) died,136(41.6%) were dual acid-base balance disorder and 80(58.8%) died,27(8.2%) were triple acid-base disturbance and 24(88.9%) died.Whereas in the control group only 83 patients(26.2%) were recognized as simple and dual acid-base balance disorder,and 18(21.7%) died.There was higher incidence of acid-base balance disorder and mortality rate in HE group than control one(P<0.001).Conclusion:Hyponatremia is valuable to judge HE patients' prognosis.The key parameters in the judgment and evaluation on acid-base balance disorder among HE patients are the change of pH values and serum electrolyte values.When pH value ≤ 7.30 or > 7.55,it generally suggests a poor prognosis. | Ren Chengshan Wang Lei Zhao Xiaoyan Yang Shiming Zhang Yanqi Wang Xiwen Bo Jianying Zhang Pengbin Guo Hong Ling Xianlong Li Yihui Da Siping Xie Xia Ren Wei Li Chunhua Qian Guisheng | 2012 | Journal of Medical Colleges of PLA(China)2012，27，3： | 3 |
| 3 | Phenotypic similarities in pigs with SOX10^(c.321dupC)and SOX10^(c.325A>T)mutations implied the correlation of SOX10 haploinsufficiency with Waardenburg syndrome显示文摘SOX10 is a causative gene of Waardenburg syndrome(WS)that is a rare genetic disorder characterized by hearing loss and pigment disturbance.More than 100 mutations of SOX10 have been found in patients with Type 2 WS(WS2),Type 4 WS(WS4),and more complex syndromes.However,no mutation hotspot has been detected in SOX10,and most cases are sporadic,making it difficult to establish a correlation between the high phenotypic and genetic variability.In this study,a duplication of the 321th cytosine(c.321dupC)was introduced into SOX10 in pigs,which induced premature termination of the translation of SOX10(p.K108QfsX45).The premature stop codon in Exon 3 triggered the degradation of mutant mRNA through nonsense-mediated mRNA decay.However,SOX10^(c.321dupC) induced a highly similar phenotype of WS2 with heterogeneous inner ear malformation compared with its adjacent missense mutation SOX10^(c.325A>T).In addition,a site-saturation mutation analysis of the SOX10 N-terminal nuclear localization signal(n-NLS),where these two mutations located,revealed the correlation between SOX10 haploinsufficiency and WS by an in vitro reporter assay.The analysis combining the in vitro assay with clinical cases may provide a clue to clinical diagnoses. | Tingting Lin Lihua Luo Weiwei Guo Wei Ren Chuanhong Liu Hong Wei Shiming Yang Yong Wang | 2020 | Journal of Genetics and Genomics2020，47，12： | 2 |
| 4 | Distributed Low-Complexity Channel Assignment for Opportunistic Routing显示文摘Opportunistic Routing (OR) involves multiple forwarding candidates to relay packets by taking advantage of the broadcast nature and multi-user diversity of a wireless medium. Compared with Traditional Routing (TR), OR is more suitable in the case of an unreliable wireless link and can evidently improve the end-to-end throughput of Wireless Mesh Networks (WMNs). In this paper, we focus on OR in Multi-Radio Multi-Channel WMNs (MRMC-WMNs). This problem has not been well examined and is considerably more challenging than the OR in single-radio wireless networks considered in the existing literature. First, we validate the advantage of OR in MRMC-WMNs. Second, we propose Low-complexity Channel Assignment for Opportunistic Routing (LcCAOR), which assigns channels to flows according to the interference state of every node. Third, we implement the LcCOAR in a fully distributed manner. The simulation result shows that compared with OR in Single-Radio Single-Channel WMNs (SRSC-WMNs), the proposed OR can significantly enhance the throughput to 87.11% and 100.3% in grid and tree WMNs, respectively. | He Shiming Zhang Dafang Xie Kun Qiao Hong Zhang Ji | 2012 | China Communications2012，9，11： | 2 |
| 5 | Diamond formation from the SiC-Co system under high pressure and high temperature显示文摘 | Shiming Hong M. Wakatsuki | 1993 | Journal of Materials Science Letters1993，，5： | 1 |
| 6 | Activated carbon fiber cloth and CaC12 composite sorbents for a watervapor sorption cooling system显示文摘 | Hong Y Zhi Y Shiming L | 2014 | Applied Thermal Engineer- ing2014，62，： | 1 |
| 7 | Chemistry and bioactivity of nobiletin and its metabolites显示文摘 | LI Shiming WANG Hong GUO Liming | 2014 | Journal of Functional Foods2014，6，1： | 1 |
| 8 | Dissolution behavior of fine particles of diamond under high pressure sintering conditions 显示文摘 | Shiming Hong Minoru Akaishi Hisao Kanda | 1991 | Journal of Materials Science Letters1991，10，3： | 1 |
| 9 | Thermodynamic prediction of the composition of Fe-based amorphous alloys显示文摘The liquidus univariant lines of the Fe-Nb-B ternary system have been thermodynamically calculated by means of CALPHAD method and Fe-based thermodynamic data. It is found that there are two eutectic reactions in the Fe-rich corner,that is,(1) L(Fe-3Nb-15B) →α+γ+ M2B (1430 K),and (2) L(Fe-10Nb-27B) → FeB + Lc14 + M2B (1575 K). Moreover,the eutectic points are very close to the compositions with high glass forming ability determined experimentally. This means that it is feasible to design the compositions of multicomponent bulk metallic glasses by looking for the eutectic points in the Fe-Nb-B system by means of thermodynamic calculation. | REN Yuping ZHANG Haifeng SUN Wensheng WANG Aimin LI Hong HU Zhuangqi HAO Shiming LI Hongxiao | 2007 | Rare Metals2007，26，5： | 0 |
| 10 | Total synthesis and stereochemistry establishmentof tumescenamide A显示文摘Tumescenamide A (1), isolated from Streptomyces tumescens YM23-20, consists of a cyclic depsipeptideand a side-chain 2,4-dimethylheptanoate (Dmh). Herein, we report the first total synthesis of tumescenamide A (1) and establish its stereochemistry. The configuration of Dmh is 2S,4S and, notably, the configuration of Val is revised as D. In addition, a mild and practical method for the β-elimination of derivatives ofserine and threonine by using nano-K_(2)CO_(3) as a base was established. A highly stereoselective synthesis ofthe Dmh substructure was also developed. | Hong Xue Shiming Fan Jingzhe Xu Shouxin Liu | 2022 | Organic Chemistry Frontiers2022，9，6： | 0 |
| 11 | Diamond synthesis from a system of chromium-carbide andNi_(70)Mn_(25)Co_5 alloy显示文摘In order to ascertain the mechanism of interaction between carbide and metallic catalyst and formation of diamond under high pressure and high temperature, and find a new method to synthesize diamond with special properties, it is necessary to investigate the reaction behavior of different carbides and metallic solvent_catalysts under high pressure and high temperature. A system of Cr-3C-2 powder and Ni 70Mn 25Co 5 alloy in weight ratio of 1∶6 was treated under 6 0 GPa and 1 500℃ for 20, 30 or 60 min respectively. X_ray diffraction of the samples indicated the Cr 3C 2 decomposed partially after high pressure and temperature treatment, and Cr 7C 3, Cr and diamond formed respectively. There was not any trace of graphite in the samples. The result suggested that the separated carbon atoms could form diamond directly without conversion process of graphite into diamond. The observation of SEI, WDX and EDX also showed that diamond crystals were synthesized in the system, which have perfect surfaces and shapes, with the average grain size of about 40 μm. The properties of the crystals are being investigated. | LI Liangbin 1, JIANG Jinchun 1, HONG Shiming 1, ZHONG Yumao 2 and ZHANG Xinyuan 2 1. Institute of Applied Physics, Sichuan Union University, Chengdu 610065, China 2. Center for Analysis and Test, Sichuan Union University, Chengdu 610065, China | 1998 | Chinese Science Bulletin1998，43，24： | 0 |
| 12 | Metabolome profiling of stratified seeds provides insight into the regulation of dormancy in Davidia involucrata显示文摘Dove tree(Davidia involucrata),a tertiary vestige species,is well-adapted to cool conditions.Dormancy in D.involucrata seed lasts for an extremely long period of time,typically between 3 and 4 years,and this characteristic makes the species an excellent model for studying the mechanisms of seed dormancy.The molecular mechanisms governing germination control in D.involucrata are still unknown.Seed stratification have been reported to enhance germination in recalcitrant seeds.We performed a widely targeted metabolome profiling to identify metabolites and associated pathways in D.involucrata seeds from six different moist sand stratification durations(0-30 months) using the ultra-high-performance liquid chromatography-Q Exactive Orbitrap-Mass spectrometry.There was an increasing germination rate with prolonged stratification durations(12-30 months).Furthermore,we detected 10,008 metabolites in the stratified seeds.We also detected 48 differentially accumulated metabolites(DAMs) between all stratification periods in the seeds,with 10 highly conserved metabolites.Most of the differentially accumulated metabolites between unstratified and stratified seeds were enriched in purine metabolism,pyrimidine metabolism,flavone and flavonol biosynthesis,phenylpropanoid biosynthesis,and arginine biosynthesis pathways.Key phytohormones,abscisic acid,indole-3 acetic acid,and sinapic acid were differentially accumulated in the seeds and are predicted to regulate dormancy in D.involucrata.We have provided extensive metabolic information useful for future works on dove tree germination study. | Shiming Deng Qiang Xiao Cigui Xu Jian Hong Zhijun Deng Dan Jiang Shijia Luo | 2022 | Plant Diversity2022，44，4： | 0 |
| 13 | Atomic-scale Nb heterogeneity induced icosahedral short-range ordering in metallic glasses显示文摘The intrinsic origins and formation of atomic-scale structure in multicomponent alloys remain largely unknown owing to limited simulations and inaccessible experiments.Herein,we report the formation of three-dimensional periodicity from a disordered atomic-scale structure to an imperfect/perfect ordered cluster and finally to long-range translational and rotational symmetry coupled with Nb heterogeneity.Significant atomic-scale structural clustering and atomic arrangements involving solvent or solute atoms simultaneously occurred during isothermal annealing.A close relationship between atomic-scale structural evolution and composition variation has important implications in depicting the chemical and topological packing during the early crystallization stage in metallic glasses.This work can provide a comprehensive understanding of how short-range orders evolve into long-range periodicity and will further shed light on the origins and nature of metallic glasses. | Yuhui Zhu Weizhen Wang Yuanyuan Song Shiming Zhang Hong Li Aimin Wang Haifeng Zhang Zhengwang Zhu | 2022 | Journal of Materials Science & Technology2022，，13： | 0 |
| 14 | A VMIMO-Based Cooperative Routing Algorithm for Maximizing Network Lifetime显示文摘Energy efficiency is an important criterion for routing algorithms in the wireless sensor network. Cooperative routing can reduce energy consumption effectively stemming from its diversity gain advantage. To solve the energy consumption problem and maximize the network lifetime, this paper proposes a Virtual Multiple Input Multiple Output based Cooperative Routing algorithm(VMIMOCR). VMIMOCR chooses cooperative relay nodes based on Virtual Multiple Input Multiple Output Model, and balances energy consumption by reasonable power allocation among transmitters, and decides the forwarding path finally. The experimental results show that VMIMOCR can improve network lifetime from 37% to 348% in the medium node density, compared with existing routing algorithms. | Ji Zhang Dafang Zhang Kun Xie Hong Qiao Shiming He | 2017 | China Communications2017，14，4： | 0 |
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