|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | LSTM Based Reserve Prediction for Bank Outlets显示文摘Reserve allocation is a significant problem faced by commercial banking businesses every day. To satisfy the cash requirement of customers and abate the vault cash pressure, commercial banks need to appropriately allocate reserves for each bank outlet. Excessive reserve would impact the revenue of bank outlets. Low reserves cannot guarantee the successful operation of bank outlets. Considering the reserve requirement is effected by the past cash balance, we deal the reserve allocation problem as a time series prediction problem, and the Long Short Time Memory(LSTM) network is adapted to solve it. In addition, the proposed LSTM prediction model regards date property, which can affect the cash balance, as a primary factor. The experiment results show that our method outperforms some existing traditional methods. | Yu Liu Shuting Dong Mingming Lu Jianxin Wang | 2019 | Tsinghua Science and Technology2019，24，1： | 5 |
| 2 | Microcavity top-emission perovskite light-emitting diodes显示文摘Light-emitting diodes(LEDs)based on perovskites show great potential in lighting and display applications.However,although perovskite films with high photoluminescence quantum efficiencies are commonly achieved,the efficiencies of perovskite LEDs are largely limited by the low light out-coupling efficiency.Here,we show that high-efficiency perovskite LEDs with a high external quantum efficiency of 20.2% and an ultrahigh radiant exitance up to 114.9mWcm^(−2) can be achieved by employing the microcavity effect to enhance light extraction.The enhanced microcavity effect and light outcoupling efficiency are confirmed by the study of angle-dependent emission profiles.Our results show that both the optical and electrical properties of the device need to be optimized to achieve high-performance perovskite LEDs. | Yanfeng Miao Lu Cheng Wei Zou Lianghui Gu Ju Zhang Qiang Guo Qiming Peng Mengmeng Xu Yarong He Shuting Zhang Yu Cao Renzhi Li Nana Wang Wei Huang Jianpu Wang | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 3 | Physicochemical properties and structure of fluid at nano-/micro-interface:Progress in simulation and experimental study显示文摘In modern chemical engineering processes, the involvement of solid/fluid interface is the most important component of process intensification techniques, such as confined membrane separation and catalysis. In the review, we summarized the research progress of the latest theoretical and experimental works to elucidate the contribution of interface to the fluid properties and structures at nano-and micro-scale. We mainly focused on water, alcohol aqueous solution, and ionic liquids, because they are classical systems in interfacial science and/or widely involved in the industrialization process. Surface-induced fluids were observed in all reviewed systems and played a critical role in physicochemical properties and structures of outside fluid. It can even be regarded as a new interface, when the adsorption layer has a strong interaction with the solid surface. Finally, we proposed a perspective on scientific challenges in the modern chemical engineering processes and outlined future prospects. | Qingwei Gao Yumeng Zhang Shuting Xu Aatto Laaksonen Yudan Zhu Xiaoyan Ji Xiaohua Lu | 2020 | Green Energy & Environment2020，5，3： | 3 |
| 4 | Construction of robust coupling interface between MoS2 and nitrogen doped graphene for high performance sodium ion batteries显示文摘As a layered inorganic material,MoS2 has recently attracted intensive attention as anode for sodium ion batteries(SIBs).However,this anode is plagued with low electronic conductivity,serious volume expansion and sluggish kinetics,resulting in capacity fading and poor rate performance.Herein,we develop an interface engineering strategy to substantially enhance the sodium storage performance of MoS2 by incorporating layered MoS2 into three dimensional N-doped graphene scaffold.The strong coupling-interface between MoS2 and N-doped graphene scaffold can not only stabilize the MoS2 structure during sodium insertion/extraction processes,but also provide plenty of anchor sites for additional surface sodium storage.The 3D MoS2@N-doped graphene composite as anode for SIBs performs an outstanding specific capacity of 667.3 mA h g^-1 at 0.2 A g^-1,a prolonged stability with a capacity retention of 94.4%after 140cycles and excellent rate capability of 445 mA h g^-1 even at a high rate of 10 A g^-1.We combined experiment and theoretical simulation to further disclose the interaction between MoS2 and N-doped graphene,adsorption and diffusion of sodium on the composite and the corresponding sodium storage mechanism.This study opens a new door to develop high performance SIBs by introducing the interface engineering technique. | Yun Qiao Jiawei Wu Xiaoguang Cheng Yudong Pang Zhansheng Lu Xiangdong Lou Qingling Li Jin Zhao Shuting Yang Yang Liu | 2020 | Journal of Energy Chemistry2020，29，9： | 3 |
| 5 | Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer’s disease显示文摘Gene therapy represents a promising treatment for the Alzheimer’s disease(AD). However,gene delivery specific to brain lesions through systemic administration remains big challenge. In our previous work, we have developed an siRNA nanocomplex able to be specifically delivered to the amyloid plaques through surface modification with both CGN peptide for the blood–brain barrier(BBB)penetration and QSH peptide for β-amyloid binding. But, whether the as-designed nanocomplex could indeed improve the gene accumulation in the impaired neuron cells and ameliorate AD-associated symptoms remains further study. Herein, we prepared the nanocomplexes with an siRNA against β-site amyloid precursor protein-cleaving enzyme 1(BACE1), the rate-limiting enzyme of Aβ production, as the therapeutic siRNA of AD. The nanocomplexes exhibited high distribution in the Aβ deposits-enriched hippocampus, especially in the neurons near the amyloid plaques after intravenous administration. In APP/PS1 transgenic mice, the nanocomplexes down-regulated BACE1 in both mRNA and protein levels,as well as Aβ and amyloid plaques to the level of wild-type mice. Moreover, the nanocomplexes significantly increased the level of synaptophysin and rescued memory loss of the AD transgenic mice without hematological or histological toxicity. Taken together, this work presented direct evidences that the design of precise gene delivery to the AD lesions markedly improves the therapeutic outcome. | Qian Guo Xiaoyao Zheng Peng Yang Xiaoying Pang Kang Qian Pengzhen Wang Shuting Xu Dongyu Sheng Liuchang Wang Jinxu Cao Wei Lu Qizhi Zhang Xinguo Jiang | 2019 | Acta Pharmaceutica Sinica B2019，9，3： | 2 |
| 6 | Nlrc3-like is required for microglia maintenance in zebrafish显示文摘Microglia are tissue-resident macrophages residing in the central nervous system (CNS) and play critical roles in removing cellular debris and infectious agents as well as regulating neurogenesis and neuronal activities. Yet, the molecular basis underlying the establishment of microglia pool and the maintenance of their homeostasis in the CNS remain largely undefined. Here we report the identification and characterization of a mutant zebrafish, which harbors a point mutation in the nucleotide-binding oligomerization domain (NOD) like receptor gene nlrc3-like, resulting in the loss of microglia in a temperature sensitive manner. Temperature shift assay reveals that the late onset of nlrc3-like deficiency leads to excessive microglia cell death. Further analysis shows that the excessive microglia death in nlrc3-like deficient mutants is attributed, at least in part, to aberrant activation of canonical inflammasome pathway. Our study indicates that proper regulation of inflammasome cascade is critical for the maintenance of microglia homeostasis. | Tienan Wang Bo Yan Liang Lou Xi Lin Tao Yu Shuting Wu Qing Lu Wei Liu Zhibin Huang Mingjie Zhang Wenqing Zhang Zilong Wen | 2019 | Journal of Genetics and Genomics2019，46，6： | 2 |
| 7 | Electrochemical impedance study on steel corrosion in the simulated concrete system with a novel self-healing microcapsule显示文摘 | Biqin Dong Yanshuai Wang Weijian Ding Shuting Li Ningxu Han Feng Xing Youyuan Lu | 2014 | Construction and Building Materials2014，，： | 1 |
| 8 | Dual‑Performance Optimized Silks from Ultra‑Low Dose Polymer Dots Feeding and Its Absorption, Distribution and Excretion in the Silkworms显示文摘Fluorescent polymer dots(Pdots)have the advantages of excellent optical properties,great biocompatibility and high photostability.Herein,we feed ultra-low doses Pdots to silkworms for the first time and aim to prepare dual-performance modified silks.After Pdots feeding,the fluorescence signal of cocoons and degummed silks increases significantly,which is more stable and more uniform than that of post-treatment silks.Moreover,Pdots hinder the conformation transformation of silk fibroin and improve the mechanical property of twisted silk strand.The highest elongation at break point is 20.75±0.03% and breaking strength is 271.7±3.8 MPa.With excellent fluorescence and mechanical properties,the optimized silks are successfully applied as a scaffold for cell culture and imaging.Furthermore,we investigate the metabolism of Pdots in the silkworms for understanding the behaviours of Pdots in the process of silks synthesis and secretion. | Jingru Li Yuqiao Li Shuting Lu Juxiang Zhang Chunfu Zhang Liqin Xiong | 2022 | Advanced Fiber Materials2022，4，4： | 1 |
| 9 | A new method for evaluating the sewage sludge pyrolysis kinetics显示文摘 | Aimin Ji Shuting Zhang Xuebin Lu Yong Liu | 2009 | Waste Management2009，，7： | 1 |
| 10 | Two-dimensional equations for thin-films of ionic conductors显示文摘A theoretical model is developed for predicting both conduction and diffusion in thin-film ionic conductors or cables. With the linearized Poisson-Nernst-Planck(PNP)theory, the two-dimensional(2D) equations for thin ionic conductor films are obtained from the three-dimensional(3D) equations by power series expansions in the film thickness coordinate, retaining the lower-order equations. The thin-film equations for ionic conductors are combined with similar equations for one thin dielectric film to derive the 2D equations of thin sandwich films composed of a dielectric layer and two ionic conductor layers. A sandwich film in the literature, as an ionic cable, is analyzed as an example of the equations obtained in this paper. The numerical results show the effect of diffusion in addition to the conduction treated in the literature. The obtained theoretical model including both conduction and diffusion phenomena can be used to investigate the performance of ionic-conductor devices with any frequency. | Shuting LU Chunli ZHANG Weiqiu CHEN Jiashi YANG | 2018 | Applied Mathematics and Mechanics(English Edition)2018，39，8： | 1 |
| 11 | Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer's disease:a systematic review and meta-analysis显示文摘A lack of convenient and reliable biomarkers for diagnosis and prognosis is a common challenge for neurodegenerative diseases such as Alzheimer's disease(AD).Recent advancement in ultrasensitive protein assays has allowed the quantification of tau and phosphorylated tau proteins in peripheral plasma.Here we identified 66 eligible studies reporting quantification of plasma tau and phosphorylated tau 181(ptau181)using four ultrasensitive methods.Meta-analysis of these studies confirmed that the AD patients had significantly higher plasma tau and ptau181 levels compared with controls,and that the plasma tau and ptau181 could predict AD with high-accuracy area under curve of the Receiver Operating Characteristic Therefore,plasma tau and plasma ptau181 can be considered as biomarkers for AD diagnosis. | Xulong Ding Shuting Zhang Lijun Jiang Lu Wang Tao Li Peng Lei | 2021 | Translational Neurodegeneration2021，10，1： | 1 |
| 12 | 显示文摘 | Yang Shuting Zhang Yanfeng Lu Qingzhang | 2000 | Journal of Inorganic Materials2000，15，： | 1 |
| 13 | Kine tic study for Fe(NO3 )3catalyzed hemicellulose hydrolysis of different corn stover silages 显示文摘 | SUN Youshan LU Xuebin ZHANG Shuting | 2011 | Bioresource Technolo- gy2011，102，3： | 1 |
| 14 | Primary assessment of the diversity of Omicron sublineages and the epidemiologic features of autumn/winter 2022 COVID-19 wave in Chinese mainland显示文摘With the recent ongoing autumn/winter 2022 COVID-19 wave and the adjustment of public health control measures,there have been widespread SARS-CoV-2 infections in Chinese mainland.Here we have analyzed 369 viral genomes from recently diagnosed COVID-19 patients in Shanghai,identifying a large number of sublineages of the SARS-CoV-2 Omicron family.Phylogenetic analysis,coupled with contact history tracing,revealed simultaneous community transmission of two Omicron sublineages dominating the infections in some areas of China(BA.5.2 mainly in Guangzhou and Shanghai,and BF.7 mainly in Beijing)and two highly infectious sublineages recently imported from abroad(XBB and BQ.1).Publicly available data from August 31 to November 29,2022 indicated an overall severe/critical case rate of 0.035%nationwide,while analysis of 5706 symptomatic patients treated at the Shanghai Public Health Center between September 1 and December 26,2022 showed that 20 cases(0.35%)without comorbidities progressed into severe/critical conditions and 153 cases(2.68%)with COVID-19-exacerbated comorbidities progressed into severe/critical conditions.These observations shall alert healthcare providers to place more resources for the treatment of severe/critical cases.Furthermore,mathematical modeling predicts this autumn/winter wave might pass through major cities in China by the end of the year,whereas some middle and western provinces and rural areas would be hit by the upcoming infection wave in mid-to-late January 2023,and the duration and magnitude of upcoming outbreak could be dramatically enhanced by the extensive travels during the Spring Festival(January 21,2023).Altogether,these preliminary data highlight the needs to allocate resources to early diagnosis and effective treatment of severe cases and the protection of vulnerable population,especially in the rural areas,to ensure the country’s smooth exit from the ongoing pandemic and accelerate socio-economic recovery. | Gang Lu Yun Ling Minghao Jiang Yun Tan Dong Wei Lu Jiang Shuting Yu Fangying Jiang Shuai Wang Yao Dai Jinzeng Wang Geng Wu Xinxin Zhang Guoyu Meng Shengyue Wang Feng Liu Xiaohong Fan Saijuan Chen | 2023 | Frontiers of Medicine2023，17，4： | 1 |
| 15 | Host protection against Omicron BA.2.2 sublineages by prior vaccination in spring 2022 COVID-19 outbreak in Shanghai显示文摘The Omicron family of SARS-CoV-2 variants are currently driving the COVID-19 pandemic.Here we analyzed the clinical laboratory test results of 9911 Omicron BA.2.2 sublineages-infected symptomatic patients without earlier infection histories during a SARS-CoV-2 outbreak in Shanghai in spring 2022.Compared to an earlier patient cohort infected by SARS-CoV-2 prototype strains in 2020,BA.2.2 infection led to distinct fluctuations of pathophysiological markers in the peripheral blood.In particular,severe/critical cases of COVID19 post BA.2.2 infection were associated with less pro-inflammatory macrophage activation and stronger interferon alpha response in the bronchoalveolar microenvironment.Importantly,the abnormal biomarkers were significantly subdued in individuals who had been immunized by 2 or 3 doses of SARS-CoV-2 prototypeinactivated vaccines,supporting the estimation of an overall 96.02% of protection rate against severe/critical disease in the 4854 cases in our BA.2.2 patient cohort with traceable vaccination records.Furthermore,even though age was a critical risk factor of the severity of COVID-19 post BA.2.2 infection,vaccination-elicited protection against severe/critical COVID-19 reached 90.15% in patients aged≥60 years old.Together,our study delineates the pathophysiological features of Omicron BA.2.2 sublineages and demonstrates significant protection conferred by prior prototype-based inactivated vaccines. | Ziyu Fu Dongguo Liang Wei Zhang Dongling Shi Yuhua Ma Dong Wei Junxiang Xi Sizhe Yang Xiaoguang Xu Di Tian Zhaoqing Zhu Mingquan Guo Lu Jiang Shuting Yu Shuai Wang Fangyin Jiang Yun Ling Shengyue Wang Saijuan Chen Feng Liu Yun Tan Xiaohong Fan | 2023 | Frontiers of Medicine2023，17，3： | 1 |
| 16 | Study on the waste liquid crystal display treatment:{ocus on the resource re- covery显示文摘 | WANG Xinying LU Xuebin ZHANG Shuting | 2013 | Journal of Hazardous Materials2013，244，34： | 1 |
| 17 | DOPA-IGF-1 Coated HA/PLGA Microspheres Promoting Proliferation and Osteoclastic Differentiation of Rabbit Bone Mesenchymal Stem Cells显示文摘To explore the ability of dihydroxyphenylalanine-insulin-like growth factor-1 (DOPA-IGF-1) coated hydroxyapatite/poly(lactic-co-glycolic acid)(HA/PLGA) microspheres to promote the proliferation and osteoclastic differentiation of rabbit bone mesenchymal stem cells(rBMSCs), HA/PLGA microspheres with different HA content (10%, 30%, 50%, mass fraction) were prepared by electrospinning method and HA/PLGA microspheres with 50% HA were coated with IGF-1 and DOPA-IGF-1, respectively. They were co-cultured with rBMSCs, respctively. Cell counting kit-8(CCK-8) detection, confocal laser scanning microscopy(CLSM), alkaline phosphatase(ALP) detection and osteogenesis related genes COL IA1, Runx2 and bone morphogenetic protein-2(BMP-2) detection were conducted to detect the proliferation activity, cell morphology, differentiation ability and the expression level of osteogenesis-related genes of cells cultured on all microspheres groups. The results showed that rBMSCs proliferation increased in an HA content dependent manner, and cells proliferated more in the IGF-1 coated and DOPA-IGF-1 coated groups, in particular in DOPA-IGF-1 coated group, and the differences were more remarkable over time (P<0.05). HA/PLGA microspheres promoted the proliferation and osteogenic differentiation of rBMSCs, and DOPA-IGF-1 coating enhanced the proliferation and osteogenic differentiation of rBMSCs. | LIU Guomin LI Yalong YANG Shuting ZHAO Yian LU Tiancheng JIA Wenyuan JI Xuan LUO Yungang | 2019 | Chemical Research in Chinese Universities2019，35，3： | 1 |
| 18 | Effect of Sox9 on TGF-β1-mediated atrial fibrosis显示文摘Atrial fibrosis is a crucial mechanism responsible for atrial fibrillation (AF). Sex-determining region Y-box containing gene 9 (Sox9) plays a pivotal role in fibrosis of many organs such as the skin, kidney, and liver. However, there are few studies about the occurrence and maintenance of Sox9 in atrial fibrosis. In this study, we investigated the role of Sox9 in the fibrotic phenotype of human atrial tissues and rat atrial fibroblasts in vitro. In the human right atrial tissue, Masson’s trichrome staining, immunofluorescence, real-time quantitative polymerase chain reaction, and western blot analysis were carried out to explore the relationship between Sox9 & atrial fibrosis at the morphological, functional, & molecular levels. In cultured atrial fibroblasts, Sox9 was overexpressed by adenovirus or depleted by siRNA, & then, recombinant human transforming growth factor (TGF)-β1 was added. Immunofluorescence analysis, western blot analysis, Transwell assay, & scratch assay were used to analyze the cells. In patient atrial tissues, Sox9 was increased with worsened atrial fibrosis, & this increase was related to AF severity. In rat atrial fibroblasts, Sox9 was promoted by TGF-β1, & the α-smooth muscle actin (α-SMA) protein level & the ability of cell migration were increased after Sox9 overexpression by adenovirus, while the α-SMA protein level & the cell migration ability were decreased after Sox9 depletion by siRNA. In conclusion, Sox9 is involved in the regulation of fibrosis in the atria & may be located downstream of TGF-β1. Our findings may provide a new perspective to treat atrial fibrosis during AF. | Hechuan Wang Yiqi Chen Shuting Zhao Xiaowen Wang Kai Lu Hua Xiao | 2021 | Acta Biochimica et Biophysica Sinica2021，53，11： | 0 |
| 19 | KIAA1199 induces advanced biological behavior and development of ovarian cancer through activation of the IL-6/STAT3 pathway显示文摘Recently,abnormal expression of KIAA1199 has been detected in Epithelial Ovarian Cancer(EOC).However,the underlined anti-ovarian cancer mechanism of KIAA1199 remains to be enlightened.In our study,we performed to elucidate the effects of KIAA1199 on the advanced biological behavior of EOC cells through activation of the IL-6/STAT3 pathway.Confirmed by immunohistochemistry,KIAA1199 was highly expressed in ovarian borderline and malignant epithelial tumors.A retrospective analysis found that EOC patients with low expression of KIAA1199 had a significantly higher 5-year survival rate than those with high expression.Mechanistically,IL-6 was used to stimulate EOC cells,and the expression of KIAA1199,STAT3 and p-STAT3 increased after IL-6 stimulation.These results could show that KIAA1199 is transcriptionally activated by IL6/STAT3 pathway,thereby accelerating the deterioration of EOC.KIAA1199 could also be used as a poor prognosis factor and potential target in treatment. | SHUTING GU JINGYI QIN SAINAN GAO ZHEN WANG QI MENG YAN LI BING LU SONGLIN ZHOU YUNZHAO XU | 2022 | BIOCELL2022，46，3： | 0 |
| 20 | Kinetics and capacities of non-reactive phosphorus (NRP) sorption to crushed autoclaved aerated concrete (CAAC)显示文摘With growing interest in resource recovery and/or reuse,wastematerials have been considered a promising alternative for phosphorus(P)adsorption because they are low-cost and easily accessible.Crushed autoclaved aerated concrete(CAAC),as representative construction waste,has been extensively studied for P removal in ecological technologies such as treatment wetlands.However,most of the previous studies focused on the adsorption of orthophosphate,namely reactive phosphorus,and lacked attention to non-reactive phosphorus(NRP)which is widely present in sewage.This study presents the first investigation on the potential and mechanism of CAAC removing four model NRP compounds.Adsorption isotherm and kinetics of NRP onto CAAC indicate that the removal of NRP was a chemisorption process and also involved a two-step pore diffusion process.The desorption experiment shows that different NRP species showed varying degrees of desorption.Most NRP was irreversibly adsorbed on CAAC.Among the model compounds considered in this study,the adsorption capacity and hydrolysis rate of organophosphorus were much less than that of inorganic phosphorus.Moreover,the adsorption of different NRP species by CAAC in the mesocosm study was different from the results of laboratory adsorption experiments,and the possible biodegradation was essential for the conversion and removal of NRP.The findings confirmed the validity of CAAC for NRP removal and the potential advantages of CAAC in terms of costs and environmental impact.This study will contribute to a better understanding of NRP conversion and environmental fate and that can be the basis for a refined risk assessment. | Shuting Shen Xiang Li Zhuofan Geng Xiwu Lu | 2023 | Journal of Environmental Sciences2023，，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员