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| 1 | Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules显示文摘由病毒的 transduction 的四抄写因素 Oct4, Klf4, Sox2 和 c-Myc 的介绍能导致体的房间的 reprogramming 进导致的 pluripotent 干细胞(iPSCs ) ,但是 iPSCs 的使用被病毒的交货系统的使用妨碍。导致化学药品的 reprogramming 把一条新奇途径提供给没有任何病毒的基于向量的基因修正,产生 iPSCs。尽管,以前的报告证明几个小分子能代替一些 reprogramming 因素至少二个抄写因素, Oct4 和 Klf4,仍然被要求从老鼠产生 iPSCs 胚胎的成纤维细胞。这里,我们识别特定的化学联合,它是足够的面对一个单个抄写因素从胚胎的老鼠和成年成纤维细胞允许 reprogramming, Oct4 在 20 天以内,代替 Sox2, Klf4 和 c-Myc。用这个处理产生的 iPSCs 类似于胚胎的干细胞以全球基因表示介绍的老鼠,在 vitro 并且在 vivo 的 epigenetic 地位和 pluripotency。我们也发现那 8 天 Oct4 正式就职是足够的面对小分子启用导致 Oct4 的 reprogramming,它建议 reprogramming 在开始的 8 天以内被开始并且独立于连续外长的 Oct4 表示。没有基因修正,这些发现将帮助 iPSCs 的未来产生,以及阐明位于 reprogramming 过程下面的分子的机制。 | Yanqin Li Qiang Zhang Xiaolei Yin Weifeng Yang Yuanyuan Du Pingping Hou Jian Ge Chun Liu Weiqi Zhang Xu Zhang Yetao Wu Honggang Li Kang Liu Chen Wu Zhihua Song Yang Zhao Yan Shi Hongkui Deng | 2011 | Cell Research2011，21，1： | 51 |
| 2 | Variability and reduction of atmospheric pollutants in Beijing and its surrounding area during the Beijing 2008 Olympic Games显示文摘The Beijing-Tianjin-Hebei Atmospheric Environment Monitoring Network was established by the Institute of Atmospheric Physics,Chinese Academy of Sciences.The goals of the network were to monitor and provide warnings of the atmospheric quality in Beijing and its surrounding area during the Beijing 2008 Olympic Games.The results showed that the atmospheric complex pollution exhibited high concentrations of ozone and fine particles and oxidation in summer,with a ubiquitous regional source.The regional mean concentrations of SO2,PM2.5,NO2,and O3_8h max(the maximum daily 8 h mean) and Ox were 22±11,90±40,25±5,136±35 and 112±21 μg/m3 in summer,respectively.During the Olympic Games,the mean concentration of SO2,PM2.5,NO2,O3_8h max,and Ox were 12.5±4,56±28,23±4,114±29,95±17 μg/m3 in the region,respectively,and fell by 51.0%,43.7%,13%,20.2%,and 18.9%,respectively,compared to the prophase mean before the Olympic Games.The concentration of atmospheric pollutants declined significantly and achieved the 'Green Olympics' control goal of air quality.After the Olympic Games,SO2,PM2.5 and NOx increased significantly as the temporary atmospheric pollution control measures were terminated. | XIN JinYuan WANG YueSi TANG GuiQian WANG LiLi SUN Yang WANG YingHong HU Bo SONG Tao JI DongSheng WANG WeiFeng LI Liang LIU GuangRen | 2010 | Chinese Science Bulletin2010，55，18： | 30 |
| 3 | Advanced rechargeable lithium-ion batteries based on bendable ZnCo2O4-urchins-on-carbon-fibers electrodes显示文摘ZnCo2O4-urchins-on-carbon-fibers 矩阵的一个新奇的班被设计了,描绘,并且过去常制作高效的精力存储设备。我们获得了 1180 妈数慲畴敲 ?L 癯 ? ㈱? 的一个可逆的锂存储能力 ?? 牣慥楳杮倠 ? 挠湯整瑮 ?? 桳牯 ? 整浲 ??? 琠敨浲污琠敲瑡敭瑮 ? 瑡 ??? 鲖 ? 栀氠睯牥愠摮甠灰牥焠慵瑮汩獥映牯搠楡祬洠湩浩浵琠浥数爔?爔 吗?? | Bin Liu Xianfu Wang Boyang Liu Qiufan Wang Dongsheng Tan Weifeng Song Xiaojuan Hou Di Chen Guozhen Shen | 2013 | Nano Research2013，6，7： | 10 |
| 4 | Effects of long-term fertilization with different substitution ratios of organic fertilizer on paddy soil显示文摘In recent years,the abuse of chemical fertilizers has caused numerous environmental problems,such as soil acidification and compaction.Replacing chemical fertilizers with organic fertilizers can effectively alleviate these problems.However,the effects of alternative organic fertilizers remain unclear.To explore the effects of organic fertilizer substitution on rice yield and paddy soil physicochemical properties and bacterial community structure,we conducted a 5-year experiment using different proportions of organic fertilizer substitution in a double-cropping rice field in Jiangxi,China.Our results showed that replacing chemical fertilizers with organic fertilizers can reduce soil acidification,increase soil organic matter content,nutrient contents,and enzyme activities,improve soil physicochemical properties and microbial community,and enhance soil metabolism.Appropriate organic substitution also had positive effects on rice production.These findings enhance our understanding of the effects of different alternative organic fertilization methods and have important theoretical significance for the promotion of the use of organic fertilizers in the future. | Weifeng SONG Aiping SHU Jiai LIU Wenchong SHI Mingcong LI Wenxue ZHANG Zuzhang LI Guangrong LIU Fusheng YUAN Shuxin ZHANG Zengbing LIU Zheng GAO | 2022 | Pedosphere2022，32，4： | 7 |
| 5 | Light-controlled synthesis of uniform platinum nano- dendrites with markedly enhanced electrocatalytic activity显示文摘我们报导一在基于锌(II ) 播种途径的 situ 快在白轻照耀下面的卟啉(ZnP ) ,与悦耳的尺寸导致一致的球形的铂 nanodendrites。铂 nanodendrites 展览显著地与商业铂黑色相比向氧减小反应(ORR ) 和甲醇氧化反应(粗腐殖质) 改进了 electrocatalytic 活动。 | Weifeng Si Jia Li Huanqiao Li Shushuang Li Jie Yin Huan Xu Xinwen Guo Tao, Zhang Yujiang Song | 2013 | Nano Research2013，6，10： | 7 |
| 6 | Rhizosheath formation and involvement in foxtail millet(Setaria italica) root growth under drought stress显示文摘The rhizosheath, a layer of soil particles that adheres firmly to the root surface by a combination of root hairs and mucilage, may improve tolerance to drought stress. Setaria italica(L.) P. Beauv.(foxtail millet), a member of the Poaceae family, is an important food and fodder crop in arid regions and forms a larger rhizosheath under drought conditions. Rhizosheath formation under drought conditions has been studied, but the regulation of root hair growth and rhizosheath size in response to soil moisture remains unclear. To address this question, in this study we monitored root hair growth and rhizosheath development in response to a gradual decline in soil moisture. Here, we determined that a soil moisture level of 10%–14%(w/w)stimulated greater rhizosheath production compared to other soil moisture levels. Root hair density and length also increased at this soil moisture level, which was validated by measurement of the expression of root hair-related genes.These findings contribute to our understanding of rhizosheath formation in response to soil water stress. | Tie-Yuan Liu Nenghui Ye Tao Song Yunying Cao Bei Gao Di Zhang Fuyuan Zhu Moxian Chen Yingjiao Zhang Weifeng Xu Jianhua Zhang | 2019 | Journal of Integrative Plant Biology2019，61，4： | 6 |
| 7 | Neutralization of interleukin-17A alleviates burn-induced intestinal barrier disruption via reducing pro-inflammatory cytokines in a mouse model显示文摘Background:The intestinal barrier integrity can be disrupted due to burn injury,which is responsible for local and systemic inflammatory responses.Anti-inflammation strategy is one of the proposed therapeutic approaches to control inflammatory cascade at an early stage.Interleukin-17A(IL-17A)plays a critical role in inflammatory diseases.However,the role of IL-17A in the progression of burn-induced intestinal inflammation is poorly understood.In this study,we aimed to investigate the effect of IL-17A and associated pro-inflammatory cytokines that were deeply involved in the pathogenesis of burn-induced intestinal inflammatory injury,and furthermore,we sought to determine the early source of IL-17A in the intestine.Methods:Mouse burn model was successfully established with infliction of 30%total body surface area scald burn.The histopathological manifestation,intestinal permeability,zonula occludens-1 expression,pro-inflammatory cytokines were determined with or without IL-17A-neutralization.Flow cytometry was used to detect the major source of IL-17A^(+)cells in the intestine.Results:Burn caused intestinal barrier damage,increase of intestinal permeability,alteration of zonula occludens-1 expressions,elevation of IL-17A,IL-6,IL-1βand tumor necrosis factor-α(TNF-α),whereas IL-17A neutralization dramatically alleviated burn-induced intestinal barrier disruption,maintained zonula occludens-1 expression,and noticeably,inhibited pro-inflammatory cytokines elevation.In addition,we observed that the proportion of intestinal IL-17A^(+)Vγ4^(+)T subtype cells(but not IL-17A^(+)Vγ1^(+)T subtype cells)were increased in burn group,and neutralization of IL-17A suppressed this increase.Conclusions:The main original findings of this study are intestinal mucosa barrier is disrupted after burn through affecting the expression of pro-inflammatory cytokines,and a protective role of IL-17A neutralization for intestinal mucosa barrier is determined.Furthermore,Vγ4^(+)T cells are identified as the major early producers of IL-17A that orchestrate an inflammatory response in the burn model.These data suggest that IL-17A blockage may provide a unique target for therapeutic intervention to treat intestinal insult after burn. | Yajun Song Yang Li Ya Xiao Wengang Hu Xu Wang Pei Wang Xiaorong Zhang Jiacai Yang Yong Huang Weifeng He Chibing Huang | 2019 | Burns & Trauma2019，7，1： | 5 |
| 8 | Measurement and Spatial Distribution of Urban Agglomeration Industrial Compactness in China显示文摘Urban agglomeration (UA) compactness means spatial concentration degree of physical entities, such as cities (towns), industries, resources, funds, traffic and technologies, whose concentration is formed according to specified economic and technologic association in the process of UA formation and development. The UA industrial compactness means the concentration degree of industry and industry clusters with reference to the industrial, technologi- cal and economic relations among the cities in the UA in the process of rational industrial division and with the exten- sion of industrial chain. After analyzing the researches on compactness, this paper finds that the relevant measurement coefficient and methods reflecting industrial geographical concentration fail to link industries spatial concentration with urban spatial concentration. Taking 23 UAs as samples and classifying them by development degree, this paper probes into UA compactness and spatial distribution characteristics from the perspective of industry by adopting UA index systems of industry and measurement models. The research finds out: 1) there is obvious positive correlation between UA industrial compactness and UA development degree; 2) the spatial distribution difference of UA industrial compactness is relatively great; and 3) UA industrial compactness shows a gradually decreasing tendency from the eastern part, the middle part to the western part of China. From the research thoughts and approaches, this article suggests that studies on the UA integrated compactness measurement should be enhanced from a multidimensional perspective involving space, traffic, population density and so on. | QI Weifeng FANG Chuanglin SONG Jitao | 2008 | Chinese Geographical Science2008，18，4： | 4 |
| 9 | Genomic characterizations of H4 subtype avian influenza viruses from live poultry markets in Sichuan province of China, 2014–2015显示文摘Dear Editor,Avian influenza viruses (AIVs) have posed a serious threat to poultry production and public health. To date, more than fourteen AIV subtypes that are able to infect human beings have been documented. Also, it is suggested that new subtypes may be reported in the future, owing to the migration of wild birds and live poultry transportation (Gao, 2018).Poultry may act as a potential incubator for novel subtypes of avian influenza virus (Bi et al., 2016a; Bi et al., 2016b; Liu et al., 2014a; Su et al., 2017). Up to date, the H7N9 AIV emerged in February 2013 has caused 1,567 human cases,with a fatality rate of 39.2%(http://gffzz36b398b81f8a4a4ch5oku0up6vkvb65up.ffgz.tsg.suse.edu.cn/influenza/ | Chuansong Quan Ting Huang Xiuwei Chen Jie Zhang Qianli Wang Cheng Zhang Tiyan Zhang Lijun Zhou Liumei Shu Chunrong Long Lei Yang Xunbo Du Yingze Zhao Peipei Liu Hao Song Weifeng Shi Yuhai Bi Qiang Lv William J.Liu George F.Gao | 2018 | Science China(Life Sciences)2018，61，9： | 4 |
| 10 | Effect of acetic acid on electrochemical deposition of carbon-nitride thin film显示文摘Electrochemical deposition method was employed to prepare CNx thin film from methanol-urea solution,and it was shown that adding a little acetic acid in the solution significantly affected the deposition process.After optimizing the experiment conditions,we obtained polycrystalline grains with sizes of about 3―7μm on the faces of single crystal silicon.X-ray diffraction spectrua indicate that the grains are mainly composed of cubic phase mixed with a small amount of β and α phases. | TIAN Yu WANG JianZhong YU WeiFeng CAO RongGen SONG Yun NING XiJing | 2009 | Science China(Technological Sciences)2009，52，6： | 2 |
| 11 | Selective potassium uptake via biocompatible zeolite–polymer hybrid microbeads as promising binders for hyperkalemia显示文摘Patients with chronic kidney disease are at high risk of hyperkalemia that is associated with various lifethreatening complications.Treatments primarily rely on orally administered potassium binding agents,along with low curative effects and various side effects.Herein,direct serum potassium uptake was realized via zeolite–heparin-mimicking-polymer hybrid microbeads.The preparation process involved the synthesis of the heparin-mimicking polymer via the in situ cross-linking polymerization of acrylic acid and N-vinylpyrrolidone in polyethersulfone solution,the fabrication of microbeads via zeolite-mixing,electro-spraying and phase-inversion,and the subsequent aqueous-phase modifications based on ion-exchange and metal-leaching.An ultra-high(about 88%)amount of zeolite could be incorporated and well locked inside the polymer matrix.Potassium uptake capability was verified in water,normal saline and human serum,showing high selectivity and fast adsorption.The microbeads exhibited satisfying blood compatibility,negligible hemolysis ratio,prolonged clotting time,inhibited contact activation,and enhanced antifouling property toward serum proteins and cells.The proposed approach toward zeolite–heparin-mimicking-polymer hybrid microbeads provided a cheap,efficient and safe treatment protocol of hyperkalemia for the high-risk patients. | Zhoujun Wang Wei Sun Zhiwei Wei Jianxu Bao Xin Song Yupei Li Haifeng Ji Jue Zhang Chao He Baihai Su Weifeng Zhao Changsheng Zhao | 2021 | Bioactive Materials2021，6，2： | 2 |
| 12 | Real-time remote monitoring system for aquaculture water quality显示文摘A multi-parameters monitoring system based on wireless network was set up to achieve remote real-time monitoring of aquaculture water quality,in order to improve the quality of aquaculture products and solve such problems as being difficult in wiring and high costs in current monitoring system.In the system solar cells and lithium cells were used for power supply.The YCS-2000 dissolved oxygen sensor,pH electrode,Pt1000 temperature sensor and ammonia nitrogen sensor were used to monitor the parameters of aquaculture water quality;STM32F103 chip was used for data processing;Zigbee and GPRS modules were used for data transmission to the remote monitoring center,where the data were stored and displayed.The system was connected with aerator to realize automatic control of dissolved oxygen concentration.The test results showed high confidence level of data transmission with a packet loss rate of 0.43%.Therefore,the system could fulfill the real-time remote monitoring of aquaculture water quality and had great practical significance in reduction of labor intensity,improvement of quality of aquatic products and protection of water environment. | Luo Hongpin Li Guanglin Peng Weifeng Song Jie Bai Qiuwei | 2015 | International Journal of Agricultural and Biological Engineering2015，8，6： | 2 |
| 13 | Realizing a“solid to solid”process via in situ cathode electrolyte interface(CEI)by solvent-in-salt electrolyte for Li-S batteries显示文摘Lithium-sulfur batteries(LSBs)are regarded as the most promising next-generation energy system due to their high theoretical energy density.However,LSBs suffer the“shuttle effect”if undergoing the solid-liquid-solid sulfur conversion process during cycling.Herein,we design a solvent-in-salt(SIS)electrolyte with co-solvent vinylene carbonate(VC)to synthesize an in situ dense cathode electrolyte interface(CEI)and successfully change sulfur conversion into a solid-solid way to avoid shuttle effect by separating the contact of sulfur and ether solvent.Dense CEI is formed at the beginning of first discharge by the combined action of SIS electrolyte and filmogen VC.Experiments and simulations show that SIS electrolyte controls the initial formed lithium polysulfides(LiPSs)to stay very closely on the cathode surface,and then converts them into a dense CEI film.As a result,Coulombic efficiency(above 99%)and cycling performance of LSBs are improved.Furthermore,the in situ dense CEI can nearly stop the self-discharge of LSBs,and enable the LSBs to work under a pretty lean electrolyte condition. | Jiajun Huang Mengli Tao Weifeng Zhang Guangli Zheng Li Du Zhiming Cui Xiujun Wang Zhenxing Liang Shijun Liao Huiyu Song | 2023 | Nano Research2023，16，4： | 1 |
| 14 | Classification of groundwater contamination in Yuxi River Valley, Shaanxi Province, China显示文摘 | LI Yunfeng WANG Weifeng SONG Jin | 2009 | Bulletin of Environmental Contamination and Toxicology2009，82，： | 1 |
| 15 | Carrier-envelope phase dependence of the spectra of reflected few-cycle laser pulses in the presence of a static electric field显示文摘 | Zhang Chaojin Yang Weifeng Song Xiaohong | 2009 | Phys Rev A2009，79，04： | 1 |
| 16 | Synthesis of molecular weight controllable bimodal polyethylene from fluorinated FI–Ti catalyst coupled with ZnEt 2显示文摘 | Weifeng Liu Song Guo Zhiyang Bu Hong Fan Wen-Jun Wang Bo-Geng Li | 2013 | European Polymer Journal2013，，7： | 1 |
| 17 | Analysis of decision-making coefficients of the lint yield of upland cotton ( Gossypium hirsutum L.)显示文摘 | Yongjun Mei Weifeng Guo Shuli Fan Meizhen Song Chaoyou Pang Shuxun Yu | 2014 | Euphytica2014，，1： | 1 |
| 18 | Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation显示文摘 | Yang Zhao Xiaolei Yin Han Qin Fangfang Zhu Haisong Liu Weifeng Yang Qiang Zhang Chengang Xiang Pingping Hou Zhihua Song Yanxia Liu Jun Yong Pengbo Zhang Jun Cai Meng Liu Honggang Li Yanqin Li Xiuxia Qu Kai Cui Weiqi Zhang Tingting Xiang Yetao Wu Yiding Zh | 2008 | Cell Stem Cell2008，，5： | 1 |
| 19 | Electronic tattoos based on large-area Mo2C grown by chemical vapor deposition for electrophysiology显示文摘Tattoo electronics has attracted intensive interest in recent years due to its comfortable wearing and imperceivable sensing,and has been broadly applied in wearable healthcare and human-machine interface.However,the tattoo electrodes are mostly composed of metal films and conductive polymers.Two-dimensional(2D)materials,which are superior in conductivity and stability,are barely studied for electronic tattoos.Herein,we reported a novel electronic tattoo based on large-area Mo_(2)C film grown by chemical vapor deposition(CVD),and applied it to accurately and imperceivably acquire on-body electrophysiological signals and interface with robotics.High-quality Mo_(2)C film was obtained via optimizing the distribution of gas flow during CVD growth.According to the finite element simulation(FES),bottom surface of Cu foil covers more stable gas flow than the top surface,thus leading to more uniform Mo_(2)C film.The resulting Mo_(2)C film was transferred onto tattoo paper,showing a total thickness of~3μm,sheet resistance of 60-150Ω/sq,and skin-electrode impedance of~5×10^(5)Ω.Such thin Mo_(2)C electronic tattoo(MCET in short)can form conformal contact with skin and accurately record electrophysiological signals,including electromyography(EMG),electrocardiogram(ECG),and electrooculogram(EOG).These body signals collected by MCET can not only reflect the health status but also be transformed to control the robotics for human-machine interface. | Shiyu Wang Xin Wang Weifeng Zhang Xiaohu Shi Dekui Song Yan Zhang Yan Zhao Zihan Zhao Nan Liu | 2023 | Nano Research2023，16，3： | 1 |
| 20 | Three Novel Avastroviruses Identified in Dead Wild Crows显示文摘Dear Editor,Astroviruses(AstVs)are non-enveloped,single-stranded RNA viruses with a diameter of approximately 35 nm(Madeley and Cosgrove 1975).The genomes of AstVs range in size from 6.8 to 7.9 kb(De Benedictis et al.2011),consisting of a 5'-untranslated region(UTR),three open reading frames(ORFs),a 3'-UTR,and a poly-adenylated(polyA)tail(Pantin-Jackwood et al.2006).In 1975,AstVs were first discovered in faeces of infants(Madeley and Cosgrove 1975).Until now,a variety of animal species,including cows,sheep,pigs,dogs,deer,rats,bats,chickens,ducks,turkeys,sea lions and seals have been reported to be infected with AstVs(Tzipori et al.1981;Cattoli et al.2007;Chu et al.2008,2010;Atkins et al.2009;Toffan et al.2009;Rivera et al.2010;Guix et al.2013;Kang et al.2012;Reuter et al.2012a,2012b;Li et al.2021).Currently,AstVs comprise two genera,Mamastrovirus(MAstV)and Avastrovirus(AAstV).Herein,we describe three novel AAstVs identified from dead crow tissues.To our knowledge,this is the first report for identification of AstVs in crows. | Chunge Zhang Yongchun Yang Tao Hu Hong Zhou Cheng Zhang Jian Cao Juan Li Peihan Wang Gary Wong Xiaodu Wang Houhui Song George FGao Weifeng Shi Yuhai Bi | 2021 | Virologica Sinica2021，36，6： | 1 |
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