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| 1 | Right trisegmentectomy with thoracoabdominal approach after transarterial embolization for giant hepatic hemangioma显示文摘Hepatic hemangiomas need to be treated surgically in cases where they are accompanied with symptoms, have a risk of rupture, or are hardly distinguishable from malignancy. The present authors conducted embolization of the right hepatic artery one day before an operation for a huge hemangioma accompanied with symptoms and confirmed a decrease in its size. The authors performed a right trisegmentectomy through a J-shape incision, using a thoracoabdominal approach, and safely removed a giant hemangioma of 32.0 cm × 26.5 cm × 8.0 cm in size and 2300 g in weight. Even for inexperienced surgeons, a J-shape incision with a thoracoabdominal approach is considered a safe and useful method when right-side hepatectomy is required for a large mass in the right liver. | Hyung-Il Seo Hong Jae Jo Mun Sup Sim Suk Kim | 2009 | World Journal of Gastroenterology2009，15，27： | 22 |
| 2 | Comparative analysis of radiofrequency ablation and resection for resectable colorectal liver metastases显示文摘AIM:To evaluate the therapeutic efficacy of radiofrequency ablation(RFA)for resectable colorectal liver metastases(CRLM)compared with that of resection.METHODS:Between June 2004 and June 2009,we retrospectively analyzed 29 patients with resectable CRLMs;17 patients underwent RFA,and 12 underwent hepatic resection.All of the patients were informed about the treatment modalities and were allowed to choose either of them.RFA including an intraoperative approach was performed by a radiologist;otherwise,hepatic resection was performed by a surgeon.Comparative analysis of the two groups was performed,including comparisons of gender,age,and clinical outcomes,such as primary tumor stage and survival rates.RESULTS:The mean tumor size was significantly larger in the resection group(3.59 cm vs 2.02 cm,P<0.01),and the 5-year overall survival(OS)rate for all patients was 44.7%.There was no difference in the 5-year OS rates between the RFA and resection groups(37.8%vs66.7%).Univariate analysis indicated significantly lower5-year OS rates for patients with a tumor size>3cm.The 5-year disease-free survival(DFS)rates were17.6%and 22.2%in the RFA and resection groups,respectively(P=0.119).Univariate analysis revealed that in cases of male gender,age>65 years,T stage<Ⅳ,absence of lymphatic metastasis,and tumor size>3 cm,RFA resulted in significantly inferior 5-year DFS rates compared with surgical resection.CONCLUSION:Surgical resection revealed superior outcomes in the treatment of resectable CRLMs,particularly in cases with a hepatic tumor size>3 cm. | Sanghwa Ko Hongjae Jo Seongpil Yun Eunyoung Park Suk Kim Hyung-Il Seo | 2014 | World Journal of Gastroenterology2014，20，2： | 12 |
| 3 | Effect of serum testosterone and percent tumor volume on extra-prostatic extension and biochemical recurrence after laparoscopic radical prostatectomy显示文摘几研究表明了外科手术前的浆液睾丸激素和百分比肿瘤体积(PTV ) 在激进的前列腺切除术以后预言 extra-prostatic 扩展(EPE ) 和生物化学的复发(BCR ) 。这研究在 laparoscopic 激进分子前列腺切除术(LRP ) 以后在与 EPE 和 BCR 的关系调查了浆液睾丸激素和 PTV 的预示的意义。我们考察了经历了在 2004 和 2012 之间的 LRP 的 520 个病人。PTV 在每节作为所有视觉上估计的肿瘤 foci 的和被决定。BCR 被定义为手术后的前列腺特定的抗原(PSA ) 的二连续增加 > 0.2 ng ml 1 。为浆液总数睾丸激素的阀值是 3.0 ng ml 1 。Multivariate 逻辑回归被用来在 EPE 和 BCR 的风险上定义变量的效果。低浆液睾丸激素(< 3.0 ng ml 1) 与高浆液 PSA,格利森分数,前列腺活体检视的积极核心百分比, PTV,和所有病理学的变量被联系。在 multivariate 分析上,类似于以前的研究,浆液 PSA,活体检视积极核心百分比,格利森分数,和病理学的变量预言了 EPE 和 BCR。另外,低浆液睾丸激素(< 3.0 ng ml 1 ,调整或, 8.52;95% CI, 5.04-14.4, P= 0.001 ) 预言的 EPE 和 PTV (调整或, 1.02;95% CI, 1.01-1.05, P= 0.046 ) 预言的 BCR。除了 EPE 和 BCR 的以前的预言者,低浆液睾丸激素和 PTV 在 LRP 以后是 EPE 和 BCR 的珍贵预言者。 | Eu Chang Hwang Seong Hyeon Yu Yang Hyun Jo Seung I1 Jung Taek Won Kang Dong Deuk Kwon Chan Choi Suk Hee Heo Jun Eul Hwang Sung-Hoon Jung Tae-Young Jung | 2016 | Asian Journal of Andrology2016，18，1： | 3 |
| 4 | Gender differences in adult traumatic brain injury according to the Glasgow coma scale:A multicenter descriptive study显示文摘Purpose:Patients’gender,which can be one of the most important determinants of traumatic brain injury(TBI)outcomes,is also likely to interact with many other outcome variables of TBI.This multicenter descriptive study investigated gender differences in epidemiological,clinical,treatment,mortality,and variable characteristics in adult TBI patients.Methods:The selection criteria were defined as patients who had been diagnosed with TBI and were admitted to the hospital between January 1,2016 and December 31,2018.A total of 4468 adult TBI patients were enrolled at eight University Hospitals.Based on the list of enrolled patients,the medical records of the patients were reviewed and they were registered online at each hospital.The registered patients were classified into three groups according to the Glasgow coma scale(GCS)score:mild(13-15),moderate(9-12),and severe(3-8),and the differences between men and women in each group were investigated.The risk factors of moderated and severe TBI compared to mild TBI were also investigated.Results:The study included 3075 men and 1393 women and the proportion of total males was 68.8%.Among all the TBI patients,there were significant differences between men and women in age,past history,and GCS score.While the mild and severe TBI groups showed significant differences in age,past history,and clinical symptoms,the moderate TBI group showed significant differences in age,past history,cause of justice,and diagnosis.Conclusion:To the best of our knowledge,this multicenter study is the first to focus on gender differences of adult patients with TBI in Korea.This study shows significant differences between men and women in many aspects of adult TBI.Therefore,gender differences should be strongly considered in TBI studies. | Ki Seong Eom Jang Hun Kim Sang Hoon Yoon Seong-jong Lee Kyung-Jae Park Sung-Kon Ha Jin-gyu Choi Kwang-Wook Jo JongYeon Kim Suk Hyung Kang Jong-Hyun Kim | 2021 | Chinese Journal of Traumatology2021，24，6： | 3 |
| 5 | Effect of dopamine on electrical activity of isolated stomach muscle in cats显示文摘 | Yang Hyeok Jo MD Sang Soo Sim PhD Hyun Choi MD Dr. Myung Suk Kim MD | 1989 | Digestive Diseases and Sciences1989，，4： | 3 |
| 6 | Sex-based differences in histology,staging,and prognosis among 2983 gastric cancer surgery patients显示文摘BACKGROUND Few studies have been conducted on sex differences in the incidence, pathophysiology, and prognosis of gastric cancer(GC).AIM To analyze the differences in GC characteristics according to sex in patients who underwent surgical treatment for GC.METHODS A total of 2983 patients diagnosed with gastric adenocarcinoma who received surgical treatment at the Seoul National University Bundang Hospital between 2003 and 2017 were included.Baseline clinicopathological characteristics, histologic type of GC, overall and GC-specific survival rates, and associated risk factors were analyzed.RESULTS Among the 2983 patients, 2005(67.2%) and 978(32.8%) were males and females, respectively.The average age of the female group(59.36 years) was significantly younger than that of the male group(61.66 years;P < 0.001).Cancer of the gastric body(P < 0.001) and diffuse-type histology(P < 0.001) were more common in females than in males.This trend was more prominent in females younger than 60 years of age, with a significantly higher proportion of diffuse-type cancer than in the male group.Regardless of sex, diffuse-type GC was more common in younger patients, and the proportion of intestinal-type GC increased with age.The overall survival rate was significantly higher in females(P < 0.001).However, this difference disappeared for GC-specific survival(P = 0.168), except for the poor GC-specific survival rate in advanced-stage cancer(stage Ⅲ or above) in females(P = 0.045).The risk factors for GC-related mortality were older age, upper location of GC, and diffuse-or mixed-type histology.In terms of comorbidities, more males died from diseases other than GC, including other malignancies such as lung cancer, hepatocellular carcinoma, and pancreatic cancer, and respiratory diseases such as interstitial lung disease and chronic obstructive pulmonary disease, while there were relatively more cardiovascular or cerebrovascular deaths in females.CONCLUSION Sex-based differences in GC were observed in clinicopathological features, including age at diagnosis, tumor location, histologic type, survival rate, and comorbidities. | Yonghoon Choi Nayoung Kim Ki Wook Kim Hyeong Ho Jo Jaehyung Park Hyuk Yoon Cheol Min Shin Young Soo Park Dong Ho Lee Hyeon Jeong Oh Hye Seung Lee Young Suk Park Sang-Hoon Ahn Yun-Suhk Suh Do Joong Park Hyung-Ho Kim Ji-Won Kim Jin Won Kim Keun-Wook Lee Won Chang Ji HoonPark Yoon Jin Lee Kyoung Ho Lee Young Hoon Kim | 2022 | World Journal of Gastroenterology2022，28，9： | 2 |
| 7 | Fabrication of perovskite solar cell with high short-circuit current density(Jsc)using moth-eye structure of SiOx显示文摘The performance of solar cells is determined by three factors:the open-circuit voltage(Voc),short-circuit current density(Jsc),and fill factor(FF).The Voc and FF are determined by the material bandgap and the series/shunt resistance,respectively.However,Jsc is determined by the amount of incident light in addition to the bandgap of the material.In this study,a moth-eye pattern was formed on a glass surface via direct printing to increase the amount of incident light and thus increase Jsc-The moth-eye pattern is a typical antireflection pattern that reduces the reflection by gradually increasing the refractive index.A flat perovskite solar cell(F-PSC)and a moth-eye patterned perovskite solar cell(M-PSC)had Jsc values of 23.70 and 25.50 mA/cm^2,respectively.The power-conversion efficiencies of the F-PSC and M-PSC were 19.81%and 21.77%,respectively. | Sucheol Ju Minseop Byun Minjin Kim Junho Jun Daihong Huh Dong Suk Kim Yimhyun Jo Heon Lee | 2020 | Nano Research2020，13，4： | 1 |
| 8 | Chemokine (C-X-C Motif) Ligand 12 Is Associated with Gallbladder Carcinoma Progression and Is a Novel Independent Poor Prognostic Factor显示文摘 | Hyun Jung Lee Kyungmin Lee Dong Gwang Lee Kwang-Hee Bae Jang-Seong Kim Zhe Long Liang Song Mei Huang Yoon Suk Oh Ha Yon Kim Deog Yeon Jo Jeong-Ki Min Jin-Man Kim Hyo Jin Lee | 2012 | Clinical Cancer Research2012，，12： | 1 |
| 9 | S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for first-line treatment of patients with metastatic colorectal cancer: a randomised, non-inferiority phase 3 trial显示文摘 | Yong Sang Hong Young Suk Park Ho Yeong Lim Jeeyun Lee Tae Won Kim Kyu-pyo Kim Sun Young Kim Ji Yeon Baek Jee Hyun Kim Keun-Wook Lee Ik-Joo Chung Sang-Hee Cho Kyung Hee Lee Sang Joon Shin Hye Jin Kang Dong Bok Shin Sook Jung Jo Jae Won Lee | 2012 | Lancet Oncology2012，，11： | 1 |
| 10 | Trough plasma imatinib levels are correlated with optimal cytogenetic responses at 6 months after treat- ment with standard dose of imatinib in newly diagnosed chronic my- eloid leukemia 显示文摘 | Sang KS Suk JO Byung SK | 2011 | Leukemia & Lymphoma2011，52，： | 1 |
| 11 | Effects of Korean Red Ginseng ( Panax ginseng ), urushiol ( Rhus vernicifera Stokes), and probiotics ( Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052) on the gut–liver axis of alcoholic liver disease显示文摘 | Chang Seok Bang So Hyung Hong Ki Tae Suk Jin Bong Kim Sang Hak Han Hotaik Sung Eun Ji Kim Myoung Jo Kim Moon Young Kim Soon Koo Baik Dong Joon Kim | 2014 | Journal of Ginseng Research2014，，： | 1 |
| 12 | Frequency of rebleeding events in obscure gastrointestinal bleeding with negative capsule endoscopy显示文摘 | Ji‐Beom Kim Byong Duk Ye Yelim Song Dong‐Hoon Yang Kee Wook Jung Kyung‐Jo Kim Jeong‐Sik Byeon Seung‐Jae Myung Suk‐Kyun Yang Jin‐Ho Kim | 2013 | J Gastroenterol Hepatol2013，，5： | 1 |
| 13 | Hepatogenous Diabetes in Cirrhosis Is Related to Portal Pressure and Variceal Hemorrhage显示文摘 | Hyo Keun Jeon Moon Young Kim Soon Koo Baik Hong Jun Park Hoon Choi So Yeon Park Bo Ra Kim Jin Heon Hong Ki Won Jo Seung Yong Shin Jung Min Kim Jae Woo Kim Hyun Soo Kim Sang Ok Kwon Young Ju Kim Seung Hwan Cha Dong Joon Kim Ki Tae Suk Gab Jin Cheon Young D | 2013 | Digestive Diseases and Sciences2013，，11： | 1 |
| 14 | Treatment of melasma by low-fluence 1064 nm Q-switched Nd:YAG laser显示文摘 | Ji Hoon Sim Young Lip Park Jong Suk Lee Sung Yul Lee Won Bok Choi Hyun Jo Kim Jung Hoon Lee | 2014 | Journal of Dermatological Treatment2014，，3： | 1 |
| 15 | Cytotoxic activities of acetoxyscirpenediol and ergosterol peroxide from Paecilomyces tenuipes显示文摘 | Kyong Suk Nam Young Su Jo Young Ho Kim | 2001 | Life Sciences2001，69，： | 1 |
| 16 | Dual specificity phosphatase 6 as a predictor of invasiveness in papillary thyroid cancer显示文摘 | Jung Uee Lee Songmei Huang Min Hee Lee Seong Eun Lee Min Jeong Ryu Soung Jung Kim Yong Kyung Kim Seul Young Kim Kyong Hye Joung Jin Man Kim Minho Shong Young Suk Jo | 2012 | European Journal of Endocrinology2012，，1： | 1 |
| 17 | Associations between intakes of individual nutrients or whole food groups and non‐alcoholic fatty liver disease among K orean adults显示文摘 | Jung Mi Han An Na Jo Seung Min Lee Hyun Suk Bae Dae Won Jun Yong Kyun Cho Ki Tae Suk Jai Hoon Yoon Sang Bong Ahn Yong Jin Cho Seong Woo Kim Eun Chul Jang | 2014 | J Gastroenterol Hepatol2014，，6： | 1 |
| 18 | Bulk synthesis of transparent and homogeneous polymeric hybrid materials with ZnO quantum dots and PMMA显示文摘 | Li Shanghua Toprak Muhammet S Jo Yun Suk | 2007 | Advanced Materials2007，19，24： | 1 |
| 19 | Influence of the BRAF V600E mutation on expression of VEGF in papillary thyroid cancer显示文摘 | Young Suk Jo Shengjin Li Jung Hun Song | 2006 | J Clin Endocrin Metab2006，10，1210： | 1 |
| 20 | Caenorhabditis elegans deep lipidome profiling by using integrative mass spectrometry acquisitions reveals significantly altered lipid networks显示文摘Lipidomics coverage improvement is essential for functional lipid and pathway construction.A powerful approach to discovering organism lipidome is to combine various data acquisitions,such as full scan mass spectrometry(full MS),data-dependent acquisition(DDA),and data-independent acquisition(DIA).Caenorhabditis elegans(C.elegans)is a useful model for discovering toxic-induced metabolism,highthroughput drug screening,and a variety of human disease pathways.To determine the lipidome of C.elegans and investigate lipid disruption from the molecular level to the system biology level,we used integrative data acquisition.The methyl-tert-butyl ether method was used to extract L4 stage C.elegans after exposure to triclosan(TCS),perfluorooctanoic acid,and nanopolystyrene(nPS).Full MS,DDA,and DIA integrations were performed to comprehensively profile the C.elegans lipidome by Q-Exactive Plus MS.All annotated lipids were then analyzed using lipid ontology and pathway analysis.We annotated up to 940 lipids from 20 lipid classes involved in various functions and pathways.The biological investigations revealed that when C.elegans were exposed to nPS,lipid droplets were disrupted,whereas plasma membrane-functionalized lipids were likely to be changed in the TCS treatment group.The nPS treatment caused a significant disruption in lipid storage.Triacylglycerol,glycerophospholipid,and ether class lipids were those primarily hindered by toxicants.Finally,toxicant exposure frequently involved numerous lipid-related pathways,including the phosphoinositide 3-kinase/protein kinase B pathway.In conclusion,an integrative data acquisition strategy was used to characterize the C.elegans lipidome,providing valuable biological insights into hypothesis generation and validation. | Nguyen Hoang Anh Young Cheol Yoon Young Jin Min Nguyen Phuoc Long Cheol Woon Jung Sun Jo Kim Suk Won Kim Eun Goo Lee Daijie Wang Xiao Wang Sung Won Kwon | 2022 | Journal of Pharmaceutical Analysis2022，12，5： | 0 |
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