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| 1 | Xanthogranulomatous cholecystitis mimicking gallbladder carcinoma with a false-positive result on fluorodeoxyglucose PET显示文摘Recently, several reports have demonstrated that fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is useful in differentiating between benign and malignant lesions in the gallbladder. However, there is a limitation in the ability of FDG-PET to differentiate between inflammatory and malignant lesions. We herein present a case of xanthogranulomatous cholecystitis misdiagnosed as gallbladder carcinoma by ultrasonography and computed tomography. FDG-PET also showed increased activity. In this case, FDG-PET findings resulted in a false-positive for the diagnosis of gallbladder carcinoma.Recently, several reports have demonstrated that fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is useful in differentiating between benign and malignant lesions in the gallbladder. However, there is a limitation in the ability of FDG-PET to differentiate between inflammatory and malignant lesions. We herein present a case of xanthogranulomatous cholecystitis misdiagnosed as gallbladder carcinoma by ultrasonography and computed tomography. FDG-PET also showed increased activity. In this case, FDG-PET findings resulted in a false-positive for the diagnosis of gallbladder carcinoma. | Isamu Makino Takahiro Yamaguchi Nariatsu Sato Toshiaki Yasui Ichiro Kita | 2009 | World Journal of Gastroenterology2009，15，29： | 11 |
| 2 | The mechanism of renal stone formation and renal failure induced by administration of melamine and cyanuric acid显示文摘 | Takahiro Kobayashi Atsushi Okada Yasuhiro Fujii Kazuhiro Niimi Shuzo Hamamoto Takahiro Yasui Keiichi Tozawa Kenjiro Kohri | 2010 | Urological Research2010，，2： | 2 |
| 3 | Characteristics of Patients With Nonalcoholic Steatohepatitis Who Develop Hepatocellular Carcinoma显示文摘 | Kohichiroh Yasui Etsuko Hashimoto Yasuji Komorizono Kazuhiko Koike Shigeki Arii Yasuharu Imai Toshihide Shima Yoshihiro Kanbara Toshiji Saibara Takahiro Mori Sumio Kawata Hirofumi Uto Shiro Takami Yoshio Sumida Toshinari Takamura Miwa Kawanaka Takeshi Oka | 2011 | Clinical Gastroenterology and Hepatology2011，，5： | 2 |
| 4 | Weekly paclitaxel for heavily treated advanced or recurrent gastric cancer refractory to fluorouracil, irinotecan, and cisplatin显示文摘 | Rai Shimoyama Hirofumi Yasui Narikazu Boku Yusuke Onozawa Shuichi Hironaka Akira Fukutomi Kentaro Yamazaki Keisei Taku Takashi Kojima Nozomu Machida Akiko Todaka Hideharu Tomita Takeshi Sakamoto Takahiro Tsushima | 2009 | Gastric Cancer2009，，4： | 1 |
| 5 | Genome -Wide A* nalysis of Genes Related to Kidney Stone Formation and Elimination in the Calcium Oxalate Nephrolithiasis Model Mouse: Detection of Stone - Preventive Factors and Involvement of Maerophage Activity 显示文摘 | Atsushi Okada Takahiro Yasui Shuzo Hamamoto | 2009 | Journal of Bone and Mineral Research2009，24，5： | 1 |
| 6 | Examina- tion of alpha] adrenoceptor subtypes in the human ureter显示文摘 | Yasunori hoh Yoshiyuki Kojima Takahiro Yasui | 2007 | Int J Urol2007，14，8： | 1 |
| 7 | Extracorporeal Cardiac Shock Wave Therapy Markedly Ameliorates Ischemia-Induced Myocardial Dysfunction in Pigs in Vivo显示文摘 | Takahiro Nishida Hiroaki Shimokawa Keiji Oi Hideki Tatewaki Toyokazu Uwatoku Kohtaro Abe Yasuharu Matsumoto Noriyoshi Kajihara Masataka Eto Takehisa Matsuda Hisataka Yasui Akira Takeshita Kenji Sunagawa | 2004 | Circulation2004，，19： | 1 |
| 8 | Safety and efficacy of S-1 monotherapy in elderly patients with advanced gastric cancer显示文摘 | Takahiro Tsushima Shuichi Hironaka Narikazu Boku Nozomu Machida Kentaro Yamazaki Hirofumi Yasui Keisei Taku Akira Fukutomi Yusuke Onozawa | 2010 | Gastric Cancer2010，，4： | 1 |
| 9 | The mechanism of renal stone formation and renal failure induced by administration of melamine and cyanuric acid显示文摘 | Takahiro Kobayashi Atsushi Okada Yasuhiro Fujii Kazuhiro Niimi Shuzo Hamamoto Takahiro Yasui Keiichi Tozawa Kenjiro Kohri | 2010 | Urological Research2010，，2： | 1 |
| 10 | Characteristics of Patients With Nonalcoholic Steatohepatitis Who Develop Hepatocellular Carcinoma显示文摘 | Kohichiroh Yasui Etsuko Hashimoto Yasuji Komorizono Kazuhiko Koike Shigeki Arii Yasuharu Imai Toshihide Shima Yoshihiro Kanbara Toshiji Saibara Takahiro Mori Sumio Kawata Hirofumi Uto Shiro Takami Yoshio Sumida Toshinari Takamura Miwa Kawanaka Takeshi Oka | 2011 | Clinical Gastroenterology and Hepatology2011，，5： | 1 |
| 11 | RNF43 is a novel tumor-suppressor and prognostic indicator in clear cell renal cell carcinoma显示文摘Identifying prognostic indicators of clear cell renal cell carcinoma(ccRCC)and elucidating the mechanisms underlying ccRCC progression are crucial for improving ccRCC patient prognosis.This study investigated the clinical significance and biological role of Ring finger protein 43(RNF43)in ccRCC.Two independent cohorts of patients with ccRCC were employed to determine the prognostic significance of RNF43 by immunohistochemistry and statistical analyses.In vitro and in vivo experiments,RNA-seq,and other techniques were used to determine the biological role of RNF43 in ccRCC and related molecular mechanisms.RNF43 expression was commonly decreased in ccRCC specimens,and low expression of RNF43 indicated a higher TNM stage,SSIGN score,and WHO/ISUP grade and short survival in patients with ccRCC.Additionally,RNF43 overexpression suppressed the proliferation,migration,and targeted drug resistance of ccRCC cells,while the knockdown of RNF43 enhanced these characteristics of ccRCC.RNF43 knockdown activated YAP signaling by decreasing YAP phosphorylation by p-LATS1/2 and increasing the transcription and nuclear distribution of YAP.By contrast,RNF43 overexpression showed the opposite effects.Decreasing YAP abolished the effect of RNF43 knockdown in promoting the malignant features of ccRCC.Additionally,restoring RNF43 expression suppressed the resistance of the targeted drug pazopanib in in vivo orthotopic ccRCC.Furthermore,combining the expression of RNF43 and YAP with TNM stage or the SSIGN score exhibited greater accuracy than any of these indicators alone in assessing the postoperative prognosis of ccRCC patients.In summary,our study identified a novel tumor suppressor,RNF43,which is also a prognostic indicator and potential target for ccRCC. | DAWEI ZHU LEI ZHANG XIAOKAI SHI SHENGLIN GAO CHUANG YUE LIFENG ZHANG YU BAI QIFENG WANG ATSUSHI OKADA TAKAHIRO YASUI CHAO WANG XINGANG CUI LI ZUO | 2021 | Oncology Research2021，29，3： | 0 |
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