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| 1 | Effects of Heterogeneous Condensation on the Transonic Flow Fields on a Bump Model显示文摘In the present study, effect of the heterogeneous condensation on the characteristics of shock wave generated on the bump model in the transonic flow field was investigated numerically. As a result, it was found that, for the flow field with steady adiabatic shock wave on the bump model, the condensation with heterogeneous nucleation has a strong effect on the whole flow field, and it reduced the strength of the shock. Furthermore, the total pressure loss was dependent on the concentration of the solid particles per unit volume. | Masanori TANAKA Shigeru MATSUO Toshiaki SETOGUCHI Heuy-Dong KIM | 2005 | Journal of Thermal Science2005，14，1： | 5 |
| 2 | Nomograms for colorectal cancer:A systematic review显示文摘AIM: To assist in the selection of suitable nomograms for obtaining desired predictions in daily clinicalpractice.METHODS: We conducted electronic searches for journal articles on colorectal cancer(CRC)-associated nomograms using the search terms colon/rectal/colorectal/nomogram. Of 174 articles initially found, we retrieved 28 studies in which a nomogram for CRC was developed.RESULTS: We discuss the currently available CRCassociated nomograms, including those that predict the oncological prognosis, the short-term outcome of treatments, such as surgery or neoadjuvant chemoradiotherapy, and the future development of CRC. Developing nomograms always presents a dilemma. On the one hand, the desire to cover as wide a patient range as possible tends to produce nomograms that are too complex and yet have C-indexes that are not sufficiently high. Conversely, confining the target patients might impair the clinical applicability of constructed nomograms.CONCLUSION: The information provided in this review should be of use in selecting a nomogram suitable for obtaining desired predictions in daily clinical practice. | Kazushige Kawai Eiji Sunami Hironori Yamaguchi Soichiro Ishihara Shinsuke Kazama Hiroaki Nozawa Keisuke Hata Tomomichi Kiyomatsu Junichiro Tanaka Toshiaki Tanaka Takeshi Nishikawa Joji Kitayama Toshiaki Watanabe | 2015 | World Journal of Gastroenterology2015，21，41： | 5 |
| 3 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer显示文摘 | Toshiaki Watanabe Michio Itabashi Yasuhiro Shimada Shinji Tanaka Yoshinori Ito Yoichi Ajioka Tetsuya Hamaguchi Ichinosuke Hyodo Masahiro Igarashi Hideyuki Ishida Megumi Ishiguro Yukihide Kanemitsu Norihiro Kokudo Kei Muro Atsushi Ochiai Masahiko Oguchi Ya | 2012 | International Journal of Clinical Oncology2012，，1： | 5 |
| 4 | Breakthrough therapy for peritoneal carcinomatosis of gastric cancer:Intraperitoneal chemotherapy with taxanes显示文摘The effect of chemotherapy on peritoneal carcinomatosis(PC) of gastric cancer remains unclear.Recently,the intraperitoneal(IP) administration of taxanes [e.g.,paclitaxel(PTX) and docetaxel(DOC)] during the perioperative period has shown promising results.Herein,we summarized the rationale and methodology for using IP chemotherapy with taxanes and reviewed the clinical results.IP administered taxanes remain in the IP space at an extremely high concentration for 48-72 h.The drug directly infiltrates peritoneal metastatic nodules from the surface and then produces antitumor effects,making it ideal for IP chemotherapy.There are two types of perioperative IP chemotherapy with taxanes: neoadjuvant intraperitoneal and systemic chemotherapy and sequential perioperative intraperitoneal chemotherapy(SPIC).In SPIC,patients receive neoadjuvant IP chemotherapy and the same regimen of IP chemotherapy after cytoreductive surgery(CRS) until disease progression.Usually,a taxane dissolved in 500-1000 m L of saline at ordinary temperature is administered through an IP access port on an outpatient basis.According to phase Ⅰ?studies,the recommended doses(RD) are as follows: IP DOC,45-60 mg/m2; IP PTX [without intravenous(IV) PTX],80 mg/m2; and IP PTX(with IV PTX),20 mg/m2.Phase Ⅱ studies have reported a median survival time of 14.4-24.6 mo with a 1-year overall survival of 67%-78%.A phase Ⅲ study comparing S-1 in combination with IP and IV PTX to S-1 with IV cisplatin started in 2011.The prognosis of patients who underwent CRS was better than that of those who did not; however,this was partly due to selection bias.Although several phase Ⅱ studies have shown promising results,a randomized controlled study is needed to validate the effectiveness of IP chemotherapy with taxanes for PC of gastric cancer. | Hironori Yamaguchi Joji Kitayama Hironori Ishigami Shinsuke Kazama Hiroaki Nozawa Kazushige Kawai Keisuke Hata Tomomichi Kiyomatsu Toshiaki Tanaka Junichiro Tanaka Takeshi Nishikawa Kensuke Otani Koji Yasuda Soichiro Ishihara Eiji Sunami Toshiaki Watanabe | 2015 | World Journal of Gastrointestinal Oncology2015，7，11： | 3 |
| 5 | Results of radical distal pancreatectomy with en bloc resection of the celiac artery for locally advanced cancer of the pancreatic body显示文摘 | Satoshi Kondo Hiroyuki Katoh Satoshi Hirano Yoshiyasu Ambo Eiichi Tanaka Shunichi Okushiba Toshiaki Morikawa | 2003 | Langenbeck’s Archives of Surgery2003，，2： | 3 |
| 6 | Oxalic acid in ginger specifically denatures the acrid raphides in the unprocessed dried tuber of Pinellia ternata显示文摘Objective:Pinellia Tuber,the dried tuber of Pinellia ternata,is widely used in Japanese Kampo medicines and traditional Chinese medicines.The unprocessed Pinellia Tuber is known to cause very strong acrid irritation at oral and laryngopharynx mucosa.Recent studies have shown that the sharp needle-like crystals called raphides,that are composed of calcium oxalate and proteins,are the main causative substances of the irritation.Ginger,the rhizome of Zingiber officinale,has been used in the processing to reduce the acridity of Pinellia Tuber since before the sixth century,however,the mechanisms of reducing acridity have not been scientifically proved yet.Methods:We developed the raphides denaturation assay(RDA)to quantify the degree of denaturation in the raphides to cause irritation.By their lipophilic characters,the raphides could be extracted in petroleum ether(PE)layer from powdered Pinellia Tuber suspended in water,and the contents of the raphides in PE layer were measured by the absorbance.By this assay,we conducted the activity-guided fractionation from the boiling water extract of ginger to find the ingredients to denature the raphides.We also conducted the gustatory tests to detect the change of the irritation of the denatured raphides.Results:The treatment of powdered Pinellia Tuber suspension with ginger extract reduced the distribution of raphides in PE layer in RDA in a concentration-dependent manner.The activity-guided fractionation using RDA revealed that oxalic acid was the main active ingredient in ginger extract to denature the raphides of Pinellia Tuber.Oxalic acid reduced the lipophilicity of the raphides in the thermo-,time-,and concentration-dependent manners,and its activity was affected by pH.The treatment of powdered Pinellia Tuber suspension with oxalic acid significantly reduced its acrid irritation in gustatory test in human.Conclusions:We found that oxalic acid is the main active ingredient in ginger to reduce the acrid irritation of Pinellia Tuber. | Tsukasa Fueki Itsuki Nose Yan Liu Koichiro Tanaka Takao Namiki Toshiaki Makino | 2022 | Acupuncture and Herbal Medicine2022，2，1： | 2 |
| 7 | JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection显示文摘 | Shinji Tanaka Hiroshi Kashida Yutaka Saito Naohisa Yahagi Hiroo Yamano Shoichi Saito Takashi Hisabe Takashi Yao Masahiko Watanabe Masahiro Yoshida Shin‐ei Kudo Osamu Tsuruta Ken‐ichi Sugihara Toshiaki Watanabe Yusuke Saitoh Masahiro Igarashi Takashi Toyon | 2015 | Digestive Endoscopy2015，，4： | 2 |
| 8 | Requirement of Protocol Biopsy Before and After Complete Cessation of Immunosuppression After Liver Transplantation显示文摘 | Mami Yoshitomi Takaaki Koshiba Hironori Haga Ying Li Xiangdong Zhao Donghua Cheng Aya Miyagawa Hiromi Sakashita Tatsuaki Tsuruyama Hidenori Ohe Mikiko Ueda Shinya Okamoto Hiroto Egawa Kathryn Wood Shimon Sakaguchi Toshiaki Manabe Koichi Tanaka Shinji Uemo | 2009 | Transplantation2009，，4： | 2 |
| 9 | Safety of combined resection of the middle hepatic artery in right hemihepatectomy for hilar biliary malignancy显示文摘 | Satoshi Hirano Satoshi Kondo Eiichi Tanaka Toshiaki Shichinohe Takahiro Tsuchikawa Kentaro Kato | 2009 | Journal of Hepato - Biliary - Pancreatic Surgery2009，，6： | 1 |
| 10 | Passive Control of Condensation Shock Wave in Prandtl-Meyer Expansion Flow显示文摘In this paper,the effects of the passive technique by using the slotted wall on the characteristics of a condensation shock wave generated in a Prandtl-Meyer flow were investigated experimentally.Furthermore,in order to clarify the variation of condensation properties in the flow field.navier-Stoker equations were solved numerically using a 3rd-order MUSCL type TVD finite-difference scheme with a second-order fractional-step for time integration.Baldwin-Lomax odel was used as a turbulence model in the computations.From experimental results,it was found that the shock strength on the slotted wall became weak in compariosn with no passive case(solid wall),and the present passive technique was the most effective when a foot of the condensation shock wave was located at the middle of slotted wall.Furthermore.it was confirmed numerically that the passive technique was also effective for the unsteady condensation shock wave. | Shigeru Matsuo Masanori Tanaka Toshiaki Setoguchi Heuy-Dong Kim | 2003 | Journal of Thermal Science2003，12，1： | 1 |
| 11 | Role of Hepatectomy in the Treatment of Hilar Bile Duct Carcinoma显示文摘 | Takahiro Tsuchikawa Satoshi Kondo Satoshi Hirano Eiichi Tanaka Yoshiyasu Anbo Toshiaki Morikawa Shunichi Okushiba Hiroyuki Katoh | 2004 | Surgery Today2004，，5： | 1 |
| 12 | β‐amyloid in lewy body disease is related to Alzheimer’s disease‐like atrophy显示文摘 | Hitoshi Shimada Hitoshi Shinotoh Shigeki Hirano Michie Miyoshi Koichi Sato Noriko Tanaka Tsuneyoshi Ota Kiyoshi Fukushi Toshiaki Irie Hiroshi Ito Makoto Higuchi Satoshi Kuwabara Tetsuya Suhara | 2012 | Mov Disord2012，，： | 1 |
| 13 | Tritium permeation through austenitiec stainless steel with chemically densified coating as a tritium permeation barrier显示文摘 | Takayuki Terai Toshiaki Yoneoka Himhisa Tanaka | 1994 | Journal of Nuclear Materials1994，，： | 1 |
| 14 | Heat resistanee properties of poly (p-phenylene 2, 6- benzobisoxazole) fiber 显示文摘 | Kuroki Tadao Tanaka Yoshikazu Hokudoh Toshiaki | 1997 | Journal of Applied Polymer Science1997，65，5： | 1 |
| 15 | Portal vein resection using the no‐touch technique with a hepatectomy for hilar cholangiocarcinoma显示文摘 | Eiji Tamoto Satoshi Hirano Takahiro Tsuchikawa Eiichi Tanaka Masaki Miyamoto Joe Matsumoto Kentaro Kato Toshiaki Shichinohe | | HPB0，，1： | 1 |
| 16 | Management of pulmonary hypertension in congenital diaphragmatic hernia: nitric oxide with prostaglandin-E1 versus nitric oxide alone显示文摘 | Satoko Shiyanagi Tadaharu Okazaki Hiromichi Shoji Toshiaki Shimizu Toshitaka Tanaka Satoru Takeda Kazunari Kawashima Geoffrey J. Lane Atsuyuki Yamataka | 2008 | Pediatric Surgery International2008，，10： | 1 |
| 17 | Outcome of surgical treatment of hilar cholangiocarcinoma: a special reference to postoperative morbidity and mortality显示文摘 | Satoshi Hirano Satoshi Kondo Eiichi Tanaka Toshiaki Shichinohe Takahiro Tsuchikawa Kentaro Kato Joe Matsumoto Ryosuke Kawasaki | 2010 | Journal of Hepato - Biliary - Pancreatic Sciences2010，，4： | 1 |
| 18 | Design of an Efficient Security Protocol Analyzer显示文摘 | Shinsaku KIYOMOTO Haruki OTA Toshiaki TANAKA | 2007 | Computer Science and Network Security2007，7，6： | 1 |
| 19 | Heat Resistence Properities of Poly(p-phenylene-2,6-benzobisoxazole) Fiber显示文摘 | Tadao Kuroki Yoshikazu Tanaka Toshiaki Hokudoh | 1997 | Appl Polym Sci1997，，65： | 1 |
| 20 | Ubiquitin, proteasome and parkin显示文摘 | Keiji Tanaka Toshiaki Suzuki Nobutaka Hattori Yoshikuni Mizuno | 2004 | BBA - Molecular Cell Research2004，，1： | 1 |
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