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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Synthesis and characterization of CNT/Ce-TiO_2 nanocomposite for phenol degradation显示文摘An innovative photocatalyst, Carbon nanotube (CNT) supported Ce-TiO2 nanocomposite was successfully synthesized via modi-fied sol gel method and investigated in a batch reactor for abolition of phenol under UV light spectrum. Characterization of catalyst micro-structure and internal properties were done by means of X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), scanning electron micros-copy (SEM), transmission electron microscopy (TEM) and UV-vis diffuse reflectance spectra (DRS). Ce doping can inhibit phase transfor-mation from anatase to rutile and eliminate the recombination of electron-hole pairs in the catalyst. The presence of CNT in TiO2 composite can both increase the photoactivity under UV and change surface properties to achieve sensitivity to visible light. The optimum mass ratio of CNT support and cerium (Ce) dopant in TiO2 was the prominent factor to harvest CNT/Ce-TiO2 photocatalyst nanocomposite. The results demonstrated that optimum mass ratio of CNT:TiO2:Ce was 0.02:1.0:0.06, which resulted in the great performance of the photocatalyst to de-grade about 94% of phenol in a 50 mg/L solution in only 3 h. In this paper, dissimilar role of CNT support and Ce dopant in the TiO2 photo-catalysis of phenol was also discussed. | Shaari N Tan S H Mohamed A R | 2012 | Journal of Rare Earths2012，30，7： | 12 |
| 3 | Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis. | Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 10 |
| 4 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998，，2： | 4 |
| 5 | The c-Jun N-terminal kinase pathway and apoptotic signaling (review).显示文摘 | Y R Chen T H Tan | 2000 | International Journal of Oncology2000，，4： | 2 |
| 6 | Metallothionein 2A expression is associated with cell proliferation in breast cancer显示文摘 | Jin R Chow V T Tan P H | 2002 | Carcinogenesis2002，23，1： | 2 |
| 7 | Early and intenive continuous hemofiltration for sever renal failure显示文摘 | Bent P Tan H K Bellomo R | 2001 | Ann Thoracic Surg2001，71，3： | 1 |
| 8 | Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipopro-tein A-I Protein synthesis and enhancing HDL cholesterol clearance显示文摘 | Liao D Tan H Hui R | 2006 | Circ Res2006，99，6： | 1 |
| 9 | Relationship between carbo- hydrate, nitrogen contents, and regrowth of tall rescue tillers 显示文摘 | Bahrani J Beaty E R Tan K H | 1983 | Journal o f Raneland Management1983，36，： | 1 |
| 10 | Transfer of multivariate calibration models: a review 显示文摘 | FEUDALE R N WOODY N A TAN H | 2002 | Chemom Intell Lab Syst2002，64，2： | 1 |
| 11 | On-line identification algorithm and conver- gence analysis for sandwich systems with backlash 显示文摘 | DONG R L TAN Y H | 2011 | International Journal of Control Automation and Systems2011，9，3： | 1 |
| 12 | Rheologlcal properties of semidilute hydrophobically modified alkali-soluble emul- sion polymers in sodium dodecyl sulfate and salt solutions 显示文摘 | Tan H Tam K C Jenkins R D | 2000 | Langmuir2000，16，13： | 1 |
| 13 | Antidepressants for functional gastrointestinal disorders in children显示文摘 | Tan E Smith C H Goldman R D | 2013 | Can Fam Physician2013，59，3： | 1 |
| 14 | Recursive identification algorithm for dynamic systems with output backlash and its convergence 显示文摘 | DONG R L TAN Q Y TAN Y H | 2009 | In- ternational Journal of Applied Mathematics and Computer Science2009，19，4： | 1 |
| 15 | Application of attenuated total reflectance-fourier transform infrared technique in the monitoring and control of anti-solvent crystallization显示文摘 | Yu Q Z Chou P S Tan R B H | 2006 | Ind Eng Chem Res2006，45，1： | 1 |
| 16 | Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration 显示文摘 | El Sokkary G Reiter H Tan R J | 1999 | Alcohol1999，34，6： | 1 |
| 17 | Recursive identification algorithm for dynamic systems with output backlash and its convergence 显示文摘 | DONG R TAN Q TAN Y H | 2009 | In- ternational Journal of Applied Mathematics and Computer Science2009，19，4： | 1 |
| 18 | Three-dimensional flow structures and associated turbulence in the tip region of a waterjet pump rotor blade显示文摘 | Wu H Tan D Miorini R L | 2011 | Experiments in Fluids2011，51，6： | 1 |
| 19 | One-step synthesis of methyl isobutyl ketone from acetone and hydrogen over Pd/ ( Nb20s/SiO2 ) catalysts 显示文摘 | Chen Y Z Liaw B J Tan H R | 2001 | Applied Catalysis A : General2001，205，： | 1 |
| 20 | Recursive identification for dynam- ic systems with backlash 显示文摘 | DONG R L TAN Y H CHEN H | 2010 | Asian Journal of Control2010，12，1： | 1 |
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