|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Characteristics of air pollution events over Hotan Prefecture at the southwestern edge of Taklimakan Desert, China显示文摘Hotan Prefecture is located at the southwestern edge of Taklimakan Desert, the world's largest shifting sand desert, of China. The desert is one of the main sources for frequent sand-dust weather events which strongly affect the air quality of Hotan Prefecture. Although this region is characterized by the highest annual mean PM_(10) concentration values that are routinely recorded by environmental monitoring stations across China, both this phenomenon and its underlying causes have not been adequately addressed in previous researches. Reliable pollutant PM_(10) data are currently retrieved using a tapered element oscillating microbalance(TEOM) 1400 a, a direct real-time monitor, while additional concentration values including for PM_(2.5), sulfur dioxide(SO_2), nitrogen dioxide(NO_2), carbon monoxide(CO) and ozone(O_3) have been collected in recent years by the Hotan Environmental Monitoring Station. Based on these data, this paper presents a comparison of the influences of different kinds of sand-dust weather events on PM10(or PM_(2.5)) as well as the concentrations of other gaseous pollutants in Hotan Prefecture. It is revealed that the highest monthly average PM10 concentrations are observed in the spring because of the frequent occurrence of three distinct kinds of sand-dust weather events at this time, including dust storms, blowing dust and floating dust. The floating dust makes the most significant contribution to PM_(10)(or PM_(2.5)) concentration in this region, a result that differs from eastern Chinese cities where the heaviest PM_(10) pollution occurs usually in winter and air pollution results from the excess emission of local anthropogenic pollutants. It is also shown that PM_(10) concentration varies within typical dust storms. PM_(10) concentrations vary among 20 dust storm events within Hotan Prefecture, and the hourly mean concentrations tend to sharply increase initially then slowly decreasing over time. Data collected from cities in eastern China show the opposite with the hourly mean PM_(10)(or PM_(2.5)) concentration tending to slowly increase then sharply decrease during heavy air pollution due to the excess emission of local anthropogenic pollutants. It is also found that the concentration of gaseous pollutants during sand-dust weather events tends to be lower than those cases under clear sky conditions. This indicates that these dust events effectively remove and rapidly diffuse gaseous pollutants. The analysis also shows that the concentration of SO_2 decreases gradually at the onset of all three kinds of sand-dust weather events because of rapidly increasing wind velocity and the development of favorable atmospheric conditions for diffusion. In contrast, changes in O_3 and NO_2 concentrations conformed to the opposite pattern during all three kinds of sand-dust weather events within this region, implying the inter transformation of these gas species during these events. | LI Jingxin WANG Shigong CHU Jinhua WANG Jiaxin LI Xu YUE Man SHANG Kezheng | 2018 | Journal of Arid Land2018，10，5： | 5 |
| 2 | The impacts of different kinds of dust events on PM 10 pollution in northern China显示文摘 | Shigong Wang Wei Yuan Kezheng Shang | 2006 | Atmospheric Environment2006，，40： | 2 |
| 3 | Temporal variations in aerosol composition at Lanzhou City, Northwestern China显示文摘Although Lanzhou is one of the most heavily polluted cities in China, the composition of its air pollutants have not yet been stud- ied in detail. The data of four months on the concentrations and compositions of ions from daily air-filter samples in the winter and spring during 2007-2008 were analyzed to investigate temporal trends and their possible causes. The results indicate that mean concentrations of almost all the aerosol components are greater in winter than in spring due to stronger emissions in winter and weaker localized dispersion. Spring dust storms are the major cause of the highest peak PM10 concentrations recorded during the study period; however, these elevated levels were transient. Ion concentrations related to coal combustion show the greatest reduc- tion from winter to spring, while the concentrations of strong crustal components show a less-pronounced reduction. Strong cycles in the levels of particulate matter (PM) and all ions are also observed during the winter months due to meteorological conditions. Depending on the season, nine different ions accounted for 20%-50% of the PM concentration. The particle size of polluting ions was constant at times of increasing PM concentrations (particularly during winter), whereas the particle size of crustal ions in- creased dramatically during spring dust storms. Local meteorological conditions (especially wind speed) have a strong influence on the levels of pollutants. Four dust storms were noted, including one during winter. In summary, the regional transport of desert dust from the Gobi can significantly affect air quality and the chemical composition of aerosols in Lanzhou. The dust storms can strongly increase concentration of crustal ions, which are characteristics of deserts in northwestern China. This observation is in agreement with back-trajectories, which show reduced levels of pollutant ions during dust storms. Data on nitrate:sulfate ratios in- dicate that stationary point sources are the main source of ions rather than mobile sources. | Feng She YiFan Cheng ShiGong Wang YongTao Guo JinYan Wang MinJing Ma KeZheng Shang | 2011 | Research in Cold and Arid Regions2011，3，3： | 2 |
| 4 | The impacts of different kinds of dust events on PM 10 pollution in northern China显示文摘 | Shigong Wang Wei Yuan Kezheng Shang | 2006 | Atmospheric Environment2006，，40： | 2 |
| 5 | Water-soluble PANI:PSS designed for spontaneous non-disruptive membrane penetration and direct intracellular photothermal damage on bacteria显示文摘The major challenge in the field of antibacterial agents is to overcome the low-permeability of bacteria cell membranes that protects the cells against diverse drugs.In this work,water-soluble polyaniline(PANI)-poly(p-styrenesulfonic acid)(PSS)(PANI:PSS)is found to spontaneously penetrate bacteria cellular membranes in a non-disruptive way,leaving no evidence of membrane poration/disturbance or cell death,thus avoiding side effects caused by cationic ammonia groups in traditional ammonia-containing antibacterial agents.For aqueous synthesis,which is important for biocompatibility,the polymer is synthesized via an enzyme-mimetic route relying on the catalysis of a nanozyme.Owing to its fluorescent properties,the localization of as-prepared PANI:PSS is determined by the confocal microscope,and the results confirm its rapid entry into bacteria.Under 808 nm near-infrared(NIR)irradiation,the internalized PANI:PSS generates local hyperthermia and destroys bacteria highly efficiently from inside the cells due to its excellent photothermal effects.Staphylococcus aureus(S.aureus),Methicillin-resistant Staphylococcus aureus(MRSA)and Escherichia coli(E.coli)could be effectively eliminated as well as the corresponding bacterial biofilms.Results of in vivo antibacterial experiments demonstrate excellent antibacterial activities of the water-soluble PANI:PSS without side effects.Therefore,the prepared water-soluble polymer in this study has great potential in the treatment of various bacterial infections. | Huanfeng Tang Yifan Liu Bing Li Bo Shang Jiacheng Yang Congrou Zhang Lijun Yang Kezheng Chen Wei Wang Jianfeng Liu | 2021 | Bioactive Materials2021，6，12： | 1 |
| 6 | Flash butt welding of large workpiece with industrial computer control显示文摘 | Wang KeZheng Tang Qing | 2002 | Qinghua Daxue Xuebao2002，，2： | 1 |
| 7 | Regional characteristics of three kinds of dust storm events in China显示文摘 | Shigong Wang Jinyan Wang Zijiang Zhou Kezheng Shang | 2004 | Atmospheric Environment2004，，3： | 1 |
| 8 | Automatic seam tracking system for submerged are welding with linear CCD vision sensors显示文摘 | Wang Kezheng Chen Xinzheng and Jia Gaofeng | 2003 | Journal Tsinghua University2003，43，5： | 1 |
| 9 | A study on variations of concentrations of particulate matter with different sizes in Lanzhou, China显示文摘 | Shigong Wang Xinyuan Feng Xiaoqing Zeng Yuxia Ma Kezheng Shang | 2009 | Atmospheric Environment2009，，17： | 1 |
| 10 | Simulation of the long-term transfer and fate of DDT in Lanzhou, China显示文摘 | DONG Jiyuan WANG Shigong SHANG Kezheng | 2010 | Chemosphere2010，81，4： | 1 |
| 11 | Linear array CCD visual intelligence seam tracking system显示文摘 | Su Yong Wang Kezheng He Fangdian | 1994 | China Mechanical Enginering1994，5，5： | 1 |
| 12 | Simulation of thelong-term transfer and fate of DDT in Lanzhou,China显示文摘 | DONG Jiyuan WANG Shigong SHANG Kezheng | 2010 | Chemosphere2010，81，4： | 1 |
| 13 | The impacts of different kinds of dust events on PM10 pollution in northern China 显示文摘 | WANG Shigong YUAN Wei SHANG Kezheng | 2006 | Atmos Environ2006，40，： | 1 |
| 14 | Ellagic acid ameliorates cisplatin-induced acute kidney injury by regulating inflammation and SIRT6/TNF-α signaling显示文摘De spite cisplatin has been widely used in the treatment of various cancers,the noteworthy nephrotoxicity greatly constrained its clinical value.For this reason,finding novel targeted therapies to attenuate the nephrotoxicity of cisplatin should be pretty significant.Our previous study found that histone deacetylase sirtuin 6(SIRT6)could be an ideal target for the treatment of cisplatin-induced acute kidney injury.In this study,we explored the protective effects of ellagic acid,a natural polyphenol compound that activates SIRT6,on cisplatin-induced nephrotoxicity.Pre-treatment of ellagic acid attenuated cytotoxicity of cisplatin in primary renal cells and TCMK-1 cells.Moreover,ellagic acid ameliorated renal dysfunction,apoptosis and fibrosis induced by cisplatin in mice.Furthermore,ellagic acid reduced nephrotoxicity-associated inflammatory factor interleukin(IL)-1βand IL-6 expression both in vitro and in vivo.Mechanistically,ellagic acid reversed cisplatin-reduced SIRT6 expression and diminished cisplatin-induced tumor necrosis factor(TNF)-αexpression.And SIRT6 knockdown abrogated the protective effects of ellagic acid on cisplatin-induced cell apoptosis,indicating the renal-protective effects of ellagic acid are mainly dependent on ellagic acid-mediated SIRT6 activation.Our results provide preclinical rationale for using ellagic acid as a feasible and promising agent to ameliorate cisplatin-induced acute kidney injury,and support ellagic acid as a potential adjunctive therapy for future cancer treatment. | Yuqi Gao Kezheng Peng Yida Wang Yannan Guo Chenye Zeng Rui Hua Qingfei Liu Xue Li Ying Qiu Zhao Wang | 2023 | Food Science and Human Wellness2023，12，6： | 1 |
| 15 | Improved lakeshore sediment microenvironment and enhanced denitrification efficiency by natural solid carbon sources显示文摘At present,the high level of nitrate in tailwater of wastewater treatment plants(WWTPs)has continued to cause serious environmental problems.In current study,wood chips and bark,serving as natural solid carbon source(NSCS),were applied to enhance the denitrification capacity of lakeshore sediment to remove superabundant nitrate in tailwater.The results show that NSCS had a positive effect on denitrification process for lakeshore sediment and increased the total phosphorus removal capacity by 212%-601%.Comparatively,wood chips were better in enhancing denitrification ability of lakeshore sediment for a longer time.At the 70th day,the nitrate elimination(NEL)of the wood chip-sediment integrated system(WSIS)was 20%and 9%higher than the control system(CS)and bark-sediment integrated system(BSIS),respectively.For the WSIS,the microbial activity and the abundance of nicotinamide adenine dinucleotide(NADH)were significantly increased,and the sediment anaerobic zone was rapidly formed,which were conducive to the denitrification of the sediment.At the DNA level,both groups presented an inconsistency in the abundance of functional denitrification genes with the NEL.At the enzyme level,wood chips significantly increased the nitrate and nitrite reductase activities of the sediment,and promoted denitrification.From the perspective of microbial communities,wood chips highly promoted the abundance of norank_f_BIrii41 Proteobacteria and Ruminclostridum more than other denitrifying and potential denitrifying bacteria in the process of sediment denitrification enhancement. | Shihao Gong Oscar Omondi Donde Qijia Cai Xingqiang Wu Kezheng Song Chunbo Wang Pei Hong Bangding Xiao Cuicui Tian | 2022 | International Journal of Sediment Research2022，37，6： | 0 |
| 16 | High-starchy carbohydrate diet aggravates NAFLD by increasing fatty acids influx mediated by NOX2显示文摘Nonalcoholic fatty liver disease(NAFLD)is a high-incidence lipid disorder that affects more than a quarter of the population worldwide,and dietary intervention is the recognized treatment.Starch is the main component of staple foods that are consumed daily,and the effects,metabolic pathway,and molecular mechanism of starch in the context of NAFLD remain unclear.Our study showed that a high-starch carbohydrate diet(HCD)led to the occurrence and exacerbation of NAFLD in mice.Transcriptomics and metabonomic analyses showed that the increased fatty acid influx mediated by NADPH oxidase 2(NOX2)exacerbated NAFLD.Knocking down NOX2 specifically alleviated HCD-induced NAFLD in vivo and in vitro.Moreover,the large amounts of ROS produced by NOX2 further exacerbated insulin resistance and increased lipolysis in perirenal white adipose tissue(periWAT),thereby providing fatty acids for hepatic lipid synthesis.In addition,the interaction between AMPKα1 and p47phox was the pathway that mediated the high expression of NOX2 induced by a HCD.Our study systematically demonstrated the effect of a HCD on NAFLD.Elevated fatty acid influx is a unique molecular regulatory pathway that mediates HCD-induced NAFLD exacerbation,which is different from the effect of simple sugars.Additionally,NOX2 was suggested to be a specific and effective drug target for NAFLD. | Yuqi Gao Rui Hua Kezheng Peng Yuemiao Yin Chenye Zeng Yannan Guo Yida Wang Liyuan Li Xue Li Ying Qiu Zhao Wang | 2023 | Food Science and Human Wellness2023，12，4： | 0 |
| 17 | Overexpressed SIRT6 ameliorates doxorubicin-induced cardiotoxicity and potentiates the therapeutic efficacy through metabolic remodeling显示文摘Since the utilization of anthracyclines in cancer therapy, severe cardiotoxicity has become a major obstacle. The major challenge in treating cancer patients with anthracyclines is minimizing cardiotoxicity without compromising antitumor efficacy. Herein, histone deacetylase SIRT6 expression was reduced in plasma of patients treated with anthracyclines-based chemotherapy regimens. Furthermore,overexpression of SIRT6 alleviated doxorubicin-induced cytotoxicity in cardiomyocytes, and potentiated cytotoxicity of doxorubicin in multiple cancer cell lines. Moreover, SIRT6 overexpression ameliorated doxorubicin-induced cardiotoxicity and potentiated antitumor efficacy of doxorubicin in mice, suggesting that SIRT6 overexpression could be an adjunctive therapeutic strategy during doxorubicin treatment.Mechanistically, doxorubicin-impaired mitochondria led to decreased mitochondrial respiration and ATP production. And SIRT6 enhanced mitochondrial biogenesis and mitophagy by deacetylating and inhibiting Sgk1. Thus, SIRT6 overexpression coordinated metabolic remodeling from glycolysis to mitochondrial respiration during doxorubicin treatment, which was more conducive to cardiomyocyte metabolism, thus protecting cardiomyocytes but not cancer cells against doxorubicin-induced energy deficiency. In addition, ellagic acid, a natural compound that activates SIRT6, alleviated doxorubicininduced cardiotoxicity and enhanced doxorubicin-mediated tumor regression in tumor-bearing mice.These findings provide a preclinical rationale for preventing cardiotoxicity by activating SIRT6 in cancer patients undergoing chemotherapy, but also advancing the understanding of the crucial role of SIRT6 in mitochondrial homeostasis. | Kezheng Peng Chenye Zeng Yuqi Gao Binliang Liu Liyuan Li Kang Xu Yuemiao Yin Ying Qiu Mingkui Zhang Fei Ma Zhao Wang | 2023 | Acta Pharmaceutica Sinica B2023，13，6： | 0 |
| 18 | A new method for instant correction of numerical weather prediction products in China显示文摘This paper presents a new correction method, 'instant correction method(ICM)', to improve the accuracy of numerical prediction products(NPP) and provide weather variables at grid cells. The ICM makes use of the continuity in time of the forecast errors at different forecast times to improve the accuracy of large scale NPP. To apply the ICM in China, an ensemble correction scheme is designed to correct the T213 NPP(the most popular NPP in China) through different statistical methods. The corrected T213 NPP(ICM T213 NPP) are evaluated by four popular indices: Correlation coefficient, climate anomalies correlation coefficient, root-mean-square-errors(RMSE), and confidence intervals(CI). The results show that the ICM T213 NPP are more accurate than the original T213 NPP in both the training period(2003–2008) and the validation period(2009–2010). Applications in China over the past three years indicate that the ICM is simple, fast, and reliable. Because of its low computing cost, end users in need of more accurate short-range weather forecasts around China can benefit greatly from the method. | ZHANG LanHui WANG ShiGong HE ChanSheng SHANG KeZheng MENG Lei LI Xu Brent M.LOFGREN | 2015 | Science China Earth Sciences2015，58，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员