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| 1 | Cobalt single atom site catalysts with ultrahigh metal loading for enhanced aerobic oxidation of ethylbenzene显示文摘The oxidation of hydrocarbons to produce high value-added compounds(ketones or alcohols)using oxygen in air as the only oxidant is an efficient synthetic strategy from both environmental and economic views.Herein,we successfully synthesized cobalt single atom site catalysts(Co SACs)with high metal loading of 23.58 wt.%supported on carbon nitride(CN),which showed excellent catalytic properties for oxidation of ethylbenzene in air.Moreover,Co SACs show a much higher turn-over frequency(19.6 h^(−1))than other reported non-noble catalysts under the same condition.Comparatively,the as-obtained nanosized or homogenous Co catalysts are inert to this reaction.Co SACs also exhibit high selectivity(97%)and stability(unchanged after five runs)in this reaction.DFT calculations reveal that Co SACs show a low energy barrier in the first elementary step and a high resistance to water,which result in the robust catalytic performance for this reaction. | Yu Xiong Wenming Sun Yunhu Han Pingyu Xin Xusheng Zheng Wensheng Yan Juncai Dong Jian Zhang Dingsheng Wang Yadong Li | 2021 | Nano Research2021，14，7： | 20 |
| 2 | Interspecific and intraspecific variation in specific root length drives aboveground biodiversity effects in young experimental forest stands显示文摘Aims Although the net biodiversity effect(NE)can be statistically partitioned into complementarity and selection effects(CE and SE),there are different underlying mechanisms that can cause a certain partitioning.Our objective was to assess the role of resource partitioning and species interactions as two important mechanisms that can bring about CEs by interspecific and intraspecific trait variation.Methods We measured tree height of 2493 living individuals in 57 plots and specific root length(SRL)on first-order roots of 368 of these individuals across different species richness levels(1,2,4,8 species)in a large-scale forest biodiversity and ecosystem functioning experiment in subtropical China(BEF-China)established in 2009.We describe the effects of resource partitioning between species by a fixed component of interspecific functional diversity(RaoQ)and further effects of species interactions by variable components of interspecific and intraspecific functional diversity(community weighted trait similarity and trait dissimilarity,CWS and CWD).Finally,we examined the relationships between biodiversity effects on stand-level tree height and functional diversity(RaoQ,CWS and CWD)in SRL using linear regression and assessed the relative importance of these three components of functional diversity in explaining the diversity effects.Important Findings Our results show that species richness significantly affected SRL in five and tree height in ten out of 16 species.A positive NE was generally brought about by a positive CE on stand-level tree height and related to high values of RaoQ and CWS in SRL.A positive CE was related to high values of all three components of root functional diversity(RaoQ,CWS and CWD).Our study suggests that both resource partitioning and species interactions are the underlying mechanisms of biodiversity effects on stand-level tree growth in subtropical forest. | Wensheng Bu Bernhard Schmid Xiaojuan Liu Ying Li Werner Härdtle Goddert von Oheimb Yu Liang Zhenkai Sun Yuanyuan Huang Helge Bruelheide Keping Ma | 2017 | Journal of Plant Ecology2017，10，1： | 18 |
| 3 | Recent Progress in Distributed Optical Fiber Raman Photon Sensors at China Jiliang University显示文摘在在中国 Jiliang 大学(CJLU ) 的完整的分布式的纤维拉曼光子传感器的研究,生产和应用的最近的进步的简短评论被介绍。以便改进测量距离,精确性,空间分辨率,多参数大小的能力,和完整的分布式的纤维传感器系统的智力,一种新一代纤维传感器技术基于光纤维,非线性的散布熔化原则被建议。一系列新一代完整的分布式的纤维传感器被调查并且设计,它由新产生组成极端长的距离散布与一个纤维拉曼放大器综合的光子传感器的完整的分布式的纤维拉曼和瑞利,汽车修正完整的分布式的纤维拉曼光子温度传感器基于拉曼关联双来源,完整的分布式的纤维拉曼光子温度传感器基于编码的脉搏采购原料,完整的分布式的纤维拉曼光子温度传感器 | Zaixuan ZHANG | 2012 | Photonic Sensors2012，2，2： | 8 |
| 4 | Preparation and properties of temperature sensitive paint based on Eu(DBM)_3 phen as probe molecule显示文摘Probe molecule Eu(DBM)3 phen is made up of europium oxide(Eu_2 O_3),dibenzoylmethane(DBM) and1,10-phenanthroline(phen). The temperature sensitive paint(TSP) was compounded by the polymerization of the probe molecule, methyl methacrylate(MMA) and the initiator of benzoyl peroxide(BPO).The structure, morphology, luminescence property of probe molecule and the temperature quenching property of the temperature sensitive paint(TSP) were characterized by infrared spectrometer, UV-vis spectrometer, scanning electron microscopy and fluorescence spectrometer respectively. The infrared spectrum and UV-vis spectra show that Eu and DBM form six membered rings, and Eu-O coordinate bonds form. The nanocrystals are in sphere-like morphology with an average size of approximately100 nm. Fluorescence spectra present that the performance of temperature quenching is excellent,what's more, TSP sample has different temperature sensitivity in various temperature scope. Particularly,under excitation of 286 nm, TSP has a highest temperature sensitivity between 50 and 60 ℃, and the strongest fluorescence emission reaches a peak(615 nm). It indicated that probe molecule(Eu(DBM)_3 phen) has strong luminescent intensity and the temperature quenching properties of Eu(DBM)_3 phen/PMMA is good. | Siyu Lu Jing Sun Yuan Wang Wensheng Yu Mengting Sun Siyuan Cui | 2018 | Journal of Rare Earths2018，36，6： | 8 |
| 5 | Role of ornithine decarboxylase in breast cancer显示文摘鸟氨酸 decarboxylase (ODC ) ,在 polyamine 生合成的限制率的酶那 decarboxylates 鸟氨酸到 putrescine,为癌症研究成为了一个有希望的目标。这研究的目的是在乳癌调查 ODC 的角色。我们在乳癌纸巾和四个乳癌房间检测了 ODC 的表示线,和有带 antisense ODC (rAd-ODC/Ex3as ) 的 adenoviral 向量的 transfected 乳癌房间并且检验了他们的生长和迁居。ODC 是在乳癌纸巾的 overexpressed,房间与非肿瘤纸巾和正常的胸相比衬里上皮的房间,并且在 ODCmRNA 的水平和肿瘤的阶段之间有积极关联。ODC 的表示与 cyclin D1 相关,房间周期蛋白质,在同步乳癌 MDA-MB-231 房间。rAd-ODC/Ex3as 的基因 transfection ODC 和 cyclin D1 的显著地下面调整的表示,在殖民地形成,一个抛锚无关的生长模式,和 MDA-MB-231 房间的迁移的能力的 G 0-G1 阶段,和抑制导致增长和房间周期拘捕的抑制。rAd-ODC/Ex3as 显著地也减少了 putrescine,然而并非亚精胺或精胺的集中,在 MDA-MB-231 房间。结果建议 ODC 基因可能为乳癌充当一个预示的因素,它能是一个有希望的治疗学的目标。 | Wensheng Deng Xian Jiang Yu Mei Jingzhong Sun Rong Ma Xianxi Liu Hui Sun Hui Tian Xueying Sun | 2008 | Acta Biochimica et Biophysica Sinica2008，40，3： | 8 |
| 6 | Recent Progress on Two-dimensional Electrocatalysis显示文摘Due to their unique electronic and structural properties triggered by high atomic utilization and easy surface modification,two-dimensional(2D)materials have prodigious potential in electrocatalysis for energy conversion technology in recent years.In this review,we discuss the recent progress on two-dimensional nanomaterials for electrocatalysis.Five categories including metals,transition metal compounds,non-metal,metal-organic framework and other emerging 2D nanomaterials are successively introduced.Finally,the challenges and future development directions of 2D materials for electrocatalysis are also prospected.We hope this review may be helpful for guiding the design and application of 2D nanomaterials in energy conversion technologies. | FANG Wensheng HUANG Lei ZAMAN Shahid WANG Zhitong HAN Youjia XIA Bao Yu | 2020 | Chemical Research in Chinese Universities2020，36，4： | 7 |
| 7 | Robust stabilization of multilinear interval plants显示文摘The robust D-stability of a class of multilinear interval polynomials is considered. Some sufficient conditions are given to judge the robust D-stability of the uncertain systems. In short, an uncertain system is robustly D-stable if some linear matrix inequalities are solvable. Moreover, our results are applied to the robust stabilization of multilinear interval plants. Taking advantage of the uncertainty structure information, these results are computationally tractable and effective in practice. | WANG Zhizhen, WANG Long and YU Wensheng(1. Department of Mechanics and Engineering Sciences, Peking University, Beijing 100871, China 2. Institute of Automation, Chinese Academy of Sciences, Beijing 100080, China) | 2002 | Progress in Natural Science:Materials International2002，12，7： | 5 |
| 8 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 9 | Solution to the Generalized Champagne Problem on simultaneous stabilization of linear systems显示文摘The well-known Generalized Champagne Problem on simultaneous stabilization of linear systems is solved by using complex analysis and Blondel’s technique. We give a complete answer to the open problem proposed by Patel et al., which auto-matically includes the solution to the original Champagne Problem. Based on the recent development in automated inequality-type theorem proving, a new stabiliz-ing controller design method is established. Our numerical examples significantly improve the relevant results in the literature. | GUAN Qiang WANG Long XIA BiCan YANG Lu YU WenSheng ZENG ZhenBing | 2007 | Science in China(Series F)2007，50，5： | 4 |
| 10 | Disruption of the Arabidopsis Defense Regulator Genes SAG101, EDS1, and PAD4 Confers Enhanced Freezing Tolerance显示文摘在 Arabidopsis,三个像脂肪分解酵素的管理者, SAG101, EDS1,和 PAD4,抵抗下游地行动联系蛋白质的防卫发信号。尽管在关於生命的应力的 SAG101, EDS1,和 PAD4 的角色广泛地被学习了,很少在对不能生活的压力的植物回答对他们的功能被知道。这里,我们证明 SAG101, EDS1,和 PAD4 涉及在 Arabidopsis 冻结忍耐的规定。与或没有冷环境适应, sag101, eds1,和 pad4 单身者异种,以及他们的双异种,展出同样提高的忍耐到冻结温度。在冷暴露, sag101, eds1,和 pad4 之上,异种与野类型显示出 C-REPEAT/DRE 有约束力的因素和他们的 regulonscompared 的增加的抄本层次。而且,结冰导致房间死亡和累积 ofhydrogen 过氧化物在 sag101, eds1,和 pad4 异种被改善。有的 sag101, eds1,和 pad4 异种很降低水杨酸酸(SA ) 和 diacylglycerol (DAG ) contentsthan SA 和 DAG 的野类型,和外长的申请损害了异种的结冰忍耐。而且, SA 在野类型的叶子压制了 DGAT 和 DGK 的导致寒冷的表示。这些调查结果显示 SAG101, EDS1,和 PAD4 在 Arabidopsis 涉及结冰反应,至少部分地,由 modulating SA 和 DAG 的动态平衡。 | Qin-Fang Chen Le Xu Wei-Juan Tan Liang Chen Hua Qi Li-Juan Xie Mo-Xian Chen Bin-Yi Liu Lu-Jun Yu Nan Yao Jian-Hua Zhang Wensheng Shu Shi Xiao | 2015 | Molecular Plant2015，8，10： | 4 |
| 11 | Preparation and properties of Nd,Yb:GGG polycrystalline nanopowders显示文摘Gadolinium gallium garnet(GGG)polycrystalline powders doped with Nd,Yb were prepared by co-precipitation method.The structure,phase and properties of powders were characterized by X-ray diffraction(XRD),Fourier transform infrared spectroscopy(FTIR),scanning electron microscope(SEM),energy dispersive X-ray spectroscopy(EDS)and fluorescence spectroscopy.XRD analysis indicated that the crystallization of Nd,Yb:GGG powders occur at 900��.SEM analysis showed that the morphology of the powders was irregular and the average radius is 68.74 nm.FTIR analysis manifested that pure Nd,Yb:GGG powders were formed at 900��.The fluorescence spectrum revealed that the most strong emission of Nd,Yb:GGG powders was 1030 nm,which was attributed to 2F5/2��2F7/2 of Yb3+.The possible formation mechanism of Nd,Yb:GGG powders were preliminarily discussed. | Yanmin DONG Jing SUN Wensheng YU Weihang LI Fei TENG | 2012 | Journal of Advanced Ceramics2012，1，4： | 3 |
| 12 | Mechanical decision for a class of integral inequalities显示文摘A class of integral inequalities is transformed into homogeneous symmetric polynomial inequalities beyond Tarski model,where the number of elements of the polynomial,say n,is also a variable and the coefficients are functions of n.This is closely associated with some open problems formulated recently by Yang et al.Using Timofte's dimension-decreasing method for symmetric polynomial inequalities,combined with the inequality-proving package BOTTEMA and a program of implementing the method known as successive difference substitution,we provide a procedure for deciding the nonnegativity of the corresponding polynomial inequality such that the original integral inequality is mechanically decidable;otherwise,a counterexample will be given.The effectiveness of the algorithm is illustrated by some more examples. | YANG Lu YU WenSheng YUAN RuYi | 2010 | Science China(Information Sciences)2010，53，9： | 3 |
| 13 | Particle swarm optimization and its application to seismic inversion of igneous rocks显示文摘In order to improve the fine structure inversion ability of igneous rocks for the exploration of underlying strata, based on particle swarm optimization(PSO), we have developed a method for seismic wave impedance inversion. Through numerical simulation, we tested the effects of different algorithm parameters and different model parameterization methods on PSO wave impedance inversion, and analyzed the characteristics of PSO method. Under the conclusions drawn from numerical simulation, we propose the scheme of combining a cross-moving strategy based on a divided block model and high-frequency filtering technology for PSO inversion. By analyzing the inversion results of a wedge model of a pitchout coal seam and a coal coking model with igneous rock intrusion, we discuss the vertical and horizontal resolution, stability and reliability of PSO inversion. Based on the actual seismic and logging data from an igneous area, by taking a seismic profile through wells as an example, we discuss the characteristics of three inversion methods, including model-based wave impedance inversion, multi-attribute seismic inversion based on probabilistic neural network(PNN) and wave impedance inversion based on PSO.And we draw the conclusion that the inversion based on PSO method has a better result for this igneous area. | Yang Haijun Xu Yongzhong Peng Gengxin Yu Guiping Chen Meng Duan Wensheng Zhu Yongfeng Cui Yongfu Wang Xingjun | 2017 | International Journal of Mining Science and Technology2017，27，2： | 3 |
| 14 | SETD8 induces stemness and epithelial–mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression显示文摘Pancreatic cancer(PC)is one of the most deadly diseases,and its incidence is increasing year by year.The methyltransferase SETD8 has been demonstrated to play an important role in tumor cell proliferation and metastasis.However,little is known about whether SETD8 could affect the invasion and metastasis of PC and the mechanism underlying the regulation.Based on our previous report,here,we further found that SETD8 could promote the invasion and migration of PC cells by inducing the expression of receptor tyrosine kinase-like orphan receptor 1(ROR1).ROR1 was predominantly upregulated in PC tissues and was correlated with lymph node metastasis and worse prognosis.Mechanistically,SETD8 mediated ROR1 activity and regulated PC cells invasion and migration,although promoting the expression of stemness and epithelial–mesenchymal transition-related molecules.This promotion effect disappeared when the catalytically inactive mutant SETD8 was overexpressed,which could be counteracted by the SETD8-specific methyltransferase inhibitor UNC0379.Collectively,our results demonstrate that SETD8 may be a novel prognostic factor and a therapeutic target of PC. | Mengqi Liu Yihua Shi Qiangsheng Hu Yi Qin Shunrong Ji Wensheng Liu Qifeng Zhuo Guixiong Fan Zeng Ye Changfeng Song Xianjun Yu Xiaowu Xu Wenyan Xu | 2021 | Acta Biochimica et Biophysica Sinica2021，53，12： | 2 |
| 15 | FGFBPI-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer显示文摘Fibroblast growth factor-binding protein 1(FGFBP1)promotes fibroblast growth factor(FGF)activity by releasing FGFs from extracellular matrix storage.We previously reported that the tumor suppressor F-box and WD repeat domain-containing 7 suppresses FGFBP1 by reducing expression of c-Myc,which inhibits the proliferation and migration of pancreatic cancer cells.However,the potential mechanism by which FGFBP1 facilitates pancreatic ductal adenocarcinoma(PDAC)remains unexplored.In this study,we focused on the function of FGFBP1 in the interplay between cancer-associated fibroblasts(CAFs)and pancreatic cancer cells(PCCs).Decreased FGF22 expression was detected in CAFs co-cultured with PCCs with FGFBP1 abrogation,which was verified in the cell culture medium by enzyme-linked immunosorbent assay.Active cytokine FGF22 significantly facilitated the migration and invasion of PANC-1 and Mia PaCa-2 cells.The number of penetrating PCCs cocultured with CAFs with FGF22 abrogation was significantly less than that of the control group.Interestingly,higher expressions of FGF22 and fibroblast growth factor receptor 2(FGFR2)were associated with worse prognosis of patients with PDAC and FGFR2,an independent prognostic marker of PDAC.The PANC-1 and Mia PaCa-2 cells with silenced FGFR2 showed weaker invasion and metastasis,even if these cells were simultaneously treated with cytokine FGF22.These results revealed that FGFBPI-mediated interaction between CAFs and PCCs via FGF22/FGFR2 facilitates the migration and invasion of PCCs.FGFR2 could act as a prognostic marker for patients with PDAC. | Zheng Zhang Yi Qin Shunrong Ji Wenyan Xu Mengqi Liu Qiangsheng Hu Zeng Ye Guixiong Fan Xianjun Yu Wensheng Liu Xiaowu Xu | 2021 | Acta Biochimica et Biophysica Sinica2021，53，8： | 2 |
| 16 | Fast Determination of Phenanthrene in Soil by Gas Chroma- tography-Mass Spectrometry Using Chemometric Resolution and Standard Addition Method显示文摘为在由使用煤气的层析团 spectrometry (GCMS ) 的复杂样品的部件的快决心的一个方法被开发并且在土壤为菲的定量分析使用了。在方法,窗户独立人士部件分析(WICA ) 被用于决定集体光谱和非否定的有免疫力的算法(NNIA ) 为获得色析法的侧面被采用。因此,光谱、色析法一个特定的部件的信息能从重叠和高背景的测量 GCMS 数据被获得。从不同地方收集的六件土壤样品被分析。在在分离准备样品和 elution 的乏味的预告的处理为加快分析被简化。由于矩阵的复杂性,标准增加方法为最后的 quantification 被采用。方法的适用性与一件刺的样品被验证,六件样品的结果是合理的。 | Weiwei Yu Wensheng Cai Xueguang Shao | 2013 | Chinese Journal of Chemistry2013，31，4： | 2 |
| 17 | Mutations in DNAH8 contribute to multiple morphological abnormalities of sperm flagella and male infertility显示文摘Asthenoteratospermia is an important cause of male infertility.Here,we report two infertile patients with severe asthenoteratospermia accompanied by new genetic abnormality.Whole-exome sequencing and bioinformatics analysis suggested that compound heterozygous mutations in DNAH8(MIM:603337)may be responsible for multiple morphological abnormalities of the sperm flagella(MMAF).Immunofluorescence assay showed that DNAH8 protein expression was significantly decreased in the sperm tail of the patients,and electron microscopy exhibited an abnormal flagellum ultrastructure,while clinical pregnancy could be achieved by intracytoplasmic sperm injection.Therefore,the compound heterozygous mutations in the DNAH8 gene may be responsible for MMAF. | Mingxiang Weng Yanwei Sha Yu Zeng Ningyu Huang Wensheng Liu Xinzong Zhang Huiliang Zhou | 2021 | Acta Biochimica et Biophysica Sinica2021，53，4： | 2 |
| 18 | Robust strictly positive real synthesis for the fourth-order convex combinations显示文摘For the two fourth-order polynomials a ( s ) and b ( s ), the Hurrwitz stability of their convex combina tion is necessary and snfficient for the existence of a polynomial c (s) such that c ( s ) / a ( s ) and c ( s ) / b ( s ) are both strictly positive real. | YU Wensheng(郁文生) WANG Long(王龙) | 2001 | Progress in Natural Science:Materials International2001，11，6： | 2 |
| 19 | Balancing selection and wild gene pool contribute to resistance in global rice germplasm against planthopper显示文摘Interactions and co-evolution between plants and herbivorous insects are critically important in agriculture.Brown planthopper(BPH)is the most severe insect of rice,and the biotypes adapt to feed on different rice genotypes.Here,we present genomics analyses on 1,520 global rice germplasms for resistance to three BPH biotypes.Genome-wide association studies identified 3,502 single nucleotide polymorphisms(SNPs)and 59 loci associated with BPH resistance in rice.We cloned a previously unidentified gene Bph37 that confers resistance to BPH.The associated loci showed high nucleotide diversity.Genome-wide scans for trans-species polymorphisms revealed ancient balancing selection at the loci.The secondarily evolved insect biotypes II and III exhibited significantly higher virulence and overcame more rice varieties than the primary biotype I.In response,more SNPs and loci evolved in rice for resistance to biotypes II and III.Notably,three exceptional large regions with high SNP density and resistance-associated loci on chromosomes 4 and 6 appear distinct between the resistant and susceptible rice varieties.Surprisingly,these regions in resistant rice might have been retained from wild species Oryza nivara.Our findings expand the understanding of long-term interactions between rice and BPH and provide resistance genes and germplasm resources for breeding durable BPH-resistant rice varieties. | Cong Zhou Qian Zhang Yu Chen Jin Huang Qin Guo Yi Li Wensheng Wang Yongfu Qiu Wei Guan Jing Zhang Jianping Guo Shaojie Shi Di Wu Xiaohong Zheng Lingyun Nie Jiaoyan Tan Chaomei Huang Yinhua Ma Fang Yang Xiqin Fu Bo Du Lili Zhu Rongzhi Chen Zhikang Li Longping Yuan Guangcun He | 2021 | Journal of Integrative Plant Biology2021，63，10： | 2 |
| 20 | Genome and Comparative Transcriptomics of African Wild Rice Oryza Iongistaminata Provide Insights into Molecular Mechanism of Rhizomatousness and Self-Incompatibility显示文摘Dear Editor, Oryza Iongistaminata is an African wild rice species with AA genome type possessing special traits that are highly valued for improving cultivated rice,such as strong resistance to biotic and abiotic stresses (Song et al.,1995) for improving resistance of cultivars,rhizomatousness for perennial breeding (Glover et al.,2010),and self-incompatibility (SI) for new ways to produce hybrid seeds (Ghesquiere,1986).Deciphering the genome of O.longistaminata will be the key to uncovering the mechanism of these hallmark traits and improving cultivated rice. | Yesheng Zhang Shilai Zhang Hui Liu Binying Fu Lijuan Li Min Xie Yue Song Xin Li Jing Cai Wenting Wan Ling Kui Hui Huang Jun Lyu Yang Dong Wensheng Wang Liyu Fluang Jing Zhang Qinzhong Yang Qinfi Shan Qiong Li Wangqi Huang Dayun Tao Muhua Wang Mingsheng Chen Yeisoo Yu Rod A. Wing Wen Wang Fengyi Hu | 2015 | Molecular Plant2015，8，11： | 1 |
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