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| 1 | Single grain Rb-Sr dating of euhedral and cataclastic pyrite from the Qiyugou gold deposit in western Henan, central China显示文摘The Rb-Sr isotopic dating of pyrite mineral from ore deposits can directly provide mineralization age. However, many geological factors may affect the Rb-Sr isotopic system,which baffles application of this method. Employing ultra-low procedural blank Rb-Sr method,we have dated pyrites separated from the No. 4 breccia pipe of the Qiyugou gold deposit,western Henan Province. Single grains of euhedral pyrite crystal with few microcracks yield an isochron age of 126 ± 11 Ma, which represents time of the main mineralization stage of the deposit. Pyrite grains of cataclastic type show nevertheless scattered Rb-Sr isotopic composition and no reasonable isochron can be defined. Crystal morphology and mineral inclusion studies reveal that Rb and Sr of pyrite mineral probably are preserved mainly in biotite, K-feldspar, and sericite mineral inclusions. The dating results likely suggest that cataclastic pyrite is not suitable for the Rb-Sr dating due to modification of the Rb-Sr isotopic system by later hydrothermal activity of fluid. | HAN YiGui LI XiangHui ZHANG ShiHong ZHANG YuanHou CHEN FuKun | 2007 | Chinese Science Bulletin2007，52，13： | 27 |
| 2 | Numerical Simulation and Experimental Study of Heat-fluid-solid Coupling of Double Flapper-nozzle Servo Valve显示文摘The double flapper-nozzle servo valve is widely used to launch and guide the equipment. Due to the large instantaneous flow rate of servo valve working under specific operating conditions, the temperature of servo valve would reach 120℃ and the valve core and valve sleeve deform in a short amount of time. So the control precision of servo valve significantly decreases and the clamping stagnation phenomenon of valve core appears. In order to solve the problem of degraded control accuracy and clamping stagnation of servo valve under large temperature difference circumstance, the numerical simulation of heat-fluid-solid coupling by using finite element method is done. The simulation result shows that zero position leakage of servo valve is basically impacted by oil temperature and change of fit clearance. The clamping stagnation is caused by warpage-deformation and fit clearance reduction of the valve core and valve sleeve. The distribution rules of the temperature and thermal-deformation of shell, valve core and valve sleeve and the pressure, velocity and temperature field of flow channel are also analyzed. Zero position leakage and electromagnet's current when valve core moves in full-stroke are tested using Electro-hydraulic Servo-valve Characteristic Test-bed of an aerospace sciences and technology corporation. The experimental results show that the change law of experimental current at different oil temperatures is roughly identical to simulation current. The current curve of the electromagnet is smooth when oil temperature is below 80℃, but the amplitude of current significantly increases and the hairy appears when oil temperature is above 80℃. The current becomes smooth again after the warped valve core and valve sleeve are reground. It indicates that clamping stagnation is caused by warpage-deformation and fit clearance reduction of valve core and valve sleeve. This paper simulates and tests the heat-fluid-solid coupling of double flapper-nozzle servo valve, and the obtained results provide the reference value for the design of double flapper-nozzle force feedback servo valve. | ZHAO Jianhua ZHOU Songlin LU Xianghui GAO Dianrong | 2015 | Chinese Journal of Mechanical Engineering2015，28，5： | 16 |
| 3 | Ultra-low procedural blank and the single-grain mica Rb-Sr isochron dating显示文摘Both low procedural blank and high-precision measurements of isotopic ratios are crucial for the analysis of micro samples. This study reports a chemical procedure of ultra-low blank for the high precision measurement of Sr isotopic ratios on micro samples (<1 ng level) using a new-type thermal ionization mass spectrometer IsoProbe-T, with a case study of single-grain Rb-Sr isochron dating on phlogopite from the Fuxian kimberlite in Liaoning Province. This method can be employed in studies of high resolution Rb-Sr geochronology and Sr isotopic geochemistry and thus will broaden application of the Rb-Sr isotopic system to earth sciences. | LI Qiuli HEN Fukun WANG Xiuli LI Xianghui LI Chaofeng | 2005 | Chinese Science Bulletin2005，50，24： | 15 |
| 4 | Study on the velocity structure of the crust in Southwest Yunnan of the north-south seismic belt—Results from the Menghai-Gengma-Lushui deep seismic sounding profile显示文摘Southwest Yunnan, located in the southern segment of the north-south seismic belt, is one of the regions with strong tectonic movement and seismic activity in China. Study on the characteristics of tectonic setting and deep geophysical field in the region is an important issue in basic science. In 2013, we conducted a 600-km-long Menghai-Gengma-Lushui profile of deep seismic wide-angle reflection/refraction and high-resolution seismic refraction in Southwest Yunnan. In this paper, we use 6 groups of clear intracrustal P-wave phases picked from the seismic record sections of 11 shots to build a velocity structure model of basement and 2D crustal P-wave of the region by using finite difference inversion and ray travel time forward fitting technology. The results show that, from south to north, the crust gradually thickens along the profile and its basement shows a significant lateral heterogeneity. In the vicinity of the Nanting River fault, the basement structure shows the character of alternate depressions and uplifts, and the shallowest basement is about 1.0 km. In the vicinity of Tengchong and Lancang, the basement is about 5.0 km deep. The velocity of the middle and lower crust in the region generally increases with the increasing of depth. At the block boundary and beneath the fault tectonic belt, the velocity contours show apparent irregularity and the P-wave velocity changes sharply. In this region, the Moho gradually deepens from south to north with relatively large lateral undulations. The shallowest point of the Moho is located near Menghai at a depth of about 32.0 km. The deepest point of the Moho is located near Tengchong at a depth of about 40.5 km. Between Gengma and Yongde, the Moho shows significantly fast uplifting and depressing with an amplitude of about 4.0 km. Beneath the Nanting River fault, Longling-Ruili fault, Dayingjiang fault and Tengchong volcano, the basement velocity structure, 2D crustal P-wave velocity structure, distribution of average profile velocity and intracrustal interface spreading also show significant changes from the basement to the top of the Moho, indicating that the crustal velocity and medium physical properties beneath the fault tectonic belt are apparently different from the crustal materials on its both sides, which suggests that these faults should be in a certain scale and may extend to the lower crust or the top of the upper mantle. The earthquakes in the region mainly occurred at a depth of 10–20 km, and the seismic activity is related to the intracrustal medium velocity difference and fault belt distribution. The results can serve as the important data of the crust-mantle structure for the analysis of the deep tectonic setting, earthquake precise positioning, seismogenic structure modeling of the seismic activities in Southwest Yunnan, as well as the important reference for the evaluation of seismic hazard and the planning of earthquake disaster mitigation of this region. | WANG ShuaiJun LIU BaoJin ZHANG JianShi LIU BaoFeng DUAN YuLing SONG XiangHui DENG XiaoGuo MA CeJun ZANG YiRan | 2015 | Science China Earth Sciences2015，58，12： | 13 |
| 5 | Transcriptomics-based identification of WRKY genes and characterization of a salt and hormone-responsive PgWRKY1 gene in Panax ginseng显示文摘WRKY 蛋白质属于一个抄写因素(TF ) 家庭和戏在许多植物过程,对不能生活、关於生命的压力的包括的植物回答,以及第二等的新陈代谢的动态角色。然而,在人参属人参 C ·迈耶的 WRKY 基因都没迄今为止被报导。在这研究,从甲基 jasmonate (MeJA ) 的很多 WRKY unigenes 对待偶然这种的根 transcriptome 用下一代的定序被识别技术。编码 WRKY 蛋白质的 48 有希望的 WRKY unigenes 的一个总数被消除冤屈和不完全的开的读物框架(ORF ) 获得。种系发生的分析揭示 48 WRKY TF,包括 11 组我, 36 组 II,和 1 组 III。而且,指定为 PgWRKY1 的一 MeJA 应答的 unigene 被克隆并且描绘。它包含 1077 bp 的全部 ORF 并且编码 358 氨基酸残余的多肽。PgWRKY1 蛋白质包含由保存氨基酸顺序主题 WRKYGQK 和 C 2 H 2-type 锌手指主题属于 WRKY 亚群 II-d。在洋葱和烟草外皮房间的 PgWRKY1-GFP 熔化蛋白质的 Subcellular 本地化表明 PgWRKY1 在原子核是只在场的。量的即时聚合酶链反应分析证明 PgWRKY1 的表示与叶子,茎,和种子相比在根和侧面的根是相对更高的。重要地, PgWRKY1 表示被水杨酸显著地导致酸, abscisic 酸,和 NaCl,而是由 MeJA 处理的 downregulated。这些结果建议 PgWRKY1 可能是对荷尔蒙和盐压力作出回应的多重压力可诱导的基因。 | Mohammed Nuruzzaman Hongzhe Cao Hao Xiu Tiao Luo Jijia Li Xianghui Chen Junli Luo Zhiyong Luo | 2016 | Acta Biochimica et Biophysica Sinica2016，48，2： | 12 |
| 6 | Joint spatial registration and multi-target tracking using an extended PM-CPHD filter显示文摘An extended product multi-sensor cardinalized probability hypothesis density (PM-CPHD) filter for spatial registration and multi-target tracking (MTT) is proposed. The number and states of targets and the biases of sensors are jointly estimated by this method without the data association. Monte Carlo (MC) simulation results show that the proposed method (i) outperforms, although computationally more expensive than, the extended multi-sensor PHD filter which has been proposed for joint spatial registration and MTT; (ii) outperforms the multi-sensor joint probabilistic data association (MSJPDA) filter which is also extended in this study for joint spatial registration and MTT when the clutter is relatively dense. | LIAN Feng HAN ChongZhao LIU WeiFeng LIU Jing YUAN XiangHui | 2012 | Science China(Information Sciences)2012，55，3： | 11 |
| 7 | ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome显示文摘OBJECTIVES:Anti-citrullinated protein antibodies(ACPAs)are a group of autoantibodies targeted against citrullinated proteins/peptides and are informative rheumatoid arthritis(RA)biomarkers.ACPAs also play a crucial role in RA pathogenesis,and their underlying mechanism merits investigation.METHODS:Immunohistochemical(IHC)assays were carried out to determine IL-1βlevels in ACPA+and ACPA−RA patients.PBMCderived monocytes were differentiated into macrophages before stimulation with ACPAs purified from RA patients.The localization and interaction of molecules were analyzed by confocal microscopy,co-IP,and surface plasmon resonance.RESULTS:In our study,we found that IL-1βlevels were elevated in ACPA+RA patients and that ACPAs promoted IL-1βproduction by PBMC-derived macrophages.ACPAs interacted with CD147 to enhance the interaction between CD147 and integrinβ1 and,in turn,activate the Akt/NF-κB signaling pathway.The nuclear localization of p65 promoted the expression of NLRP3 and pro-IL-1β,resulting in priming.Moreover,ACPA stimulation activated pannexin channels,leading to ATP release.The accumulated ATP bound to the P2X7 receptor,leading to NLRP3 inflammasome activation.CONCLUSIONS:Our study suggests a new hypothesis regarding IL-1βproduction in RA involving ACPAs,which may be a potential therapeutic target in RA treatment. | Xiwen Dong Zhaohui Zheng Peng Lin Xianghui Fu Fanni Li Jianli Jiang Ping Zhu | 2020 | Cellular & Molecular Immunology2020，17，3： | 11 |
| 8 | Finite Element Numerical Simulation and PIV Measurement of Flow Field inside Metering-in Spool Valve显示文摘The finite element method(FEM) and particle image velocimetry(PIV) technique are utilized to get the flow field along the inlet passage, the chamber, the metering port and the outlet passage of spool valve at three different valve openings.For FEM numerical simulation, the stream function ψ-vorticity ω forms of continuity and Navier-Stokes equations are employed and FEM is applied to discrete the equations.Homemade simulation codes are executed to compute the values of stream function and vorticity at each node in the flow domain, then according to the correlation between stream function and velocity components, the velocity vectors of the whole field are calculated.For PIV experiment, pulse Nd:YAG laser is exploited to generate laser beam, cylindrical and spherical lenses are combined each other to produce 1.0 mm thickness laser sheet to illuminate the object plane, Polystyrene spherical particle with diameter of 30?50 μm is seeded in the fluid as a tracing particles, Kodak ES1.0 CCD camera is employed to capture the images of interested, the images are processed with fast Fourier transform(FFT) cross-correlation algorithm and the processing results is displayed.Both results of numerical simulation and PIV experimental show that there are three main areas in the spool valve where vortex is formed.Numerical results also indicate that the valve opening have some effects on the flow structure of the valve.The investigation is helpful for qualitatively analyzing the energy loss, noise generating, steady state flow forces and even designing the geometry structure and flow passage. | GAO Dianrong QIAO Haijun LU Xianghui | 2009 | Chinese Journal of Mechanical Engineering2009，22，1： | 10 |
| 9 | Shuganjieyu capsule increases neurotrophic factor expression in a rat model of depression显示文摘Shuganjieyu capsule has been approved for clinical treatment by the State Food and Drug Administration of China since 2008. In the clinic, Shuganjieyu capsule is often used to treat mild to moderate depression. In the rat model of depression established in this study, Shuganjieyu capsule was administered intragastrically daily before stress. Behavioral results confirmed that depressive symptoms lessened after treatment with high-dose(150 mg/kg) Shuganjieyu capsule. Immunohistochemistry results showed that high-dose Shuganjieyu capsule significantly increased phosphorylation levels of phosphorylation cyclic adenosine monophosphate response element binding protein and brain-derived neurotrophic factor expression in the medial prefrontal cortex and hippocampal CA3 area. Overall, our results suggest that in rats, Shuganjieyu capsule effectively reverses depressive-like behaviors by increasing expression levels of neurotrophic factors in the brain. | Jinhua Fu Yingjin Zhang Renrong Wu Yingjun Zheng Xianghui Zhang Mei Yang Jingping Zhao Yong Liu | 2014 | Neural Regeneration Research2014，9，5： | 10 |
| 10 | The 2020/21 Extremely Cold Winter in China Influenced by the Synergistic Effect of La Niña and Warm Arctic显示文摘In the first half of winter 2020/21,China has experienced an extremely cold period across both northern and southern regions,with record-breaking low temperatures set in many stations of China.Meanwhile,a moderate La Niña event which exceeded both oceanic and atmospheric thresholds began in August 2020 and in a few months developed into its mature phase,just prior to the 2020/21 winter.In this report,the mid−high-latitude large-scale atmospheric circulation anomalies in the Northern Hemisphere,which were forced by the negative phase of Arctic Oscillation,a strengthened Siberian High,an intensified Ural High and a deepened East Asian Trough,are considered to be the direct reason for the frequent cold surges in winter 2020/21.At the same time,the synergistic effect of the warm Arctic and the cold tropical Pacific(La Niña)provided an indispensable background,at a hemispheric scale,to intensify the atmospheric circulation anomalies in middle-to-high latitudes.In the end,a most recent La Niña prediction is provided and the on-coming evolution of climate is discussed for the remaining part of the 2020/21 winter for the purpose of future decision-making and early warning. | Fei ZHENG Yuan YUAN Yihui DING Kexin LI Xianghui FANG Yuheng ZHAO Yue SUN Jiang ZHU Zongjian KE Ji WANG Xiaolong JIA | 2022 | Advances in Atmospheric Sciences2022，39，4： | 7 |
| 11 | Preoperative serum alkaline phosphatase: a predictive factor for early hypocalcaemia following parathyroidectomy of primary hyperparathyroidism显示文摘 | Sun Longhao He Xianghui Liu Tong | 2014 | Chinese Medical Journal2014，，18： | 7 |
| 12 | Analysis of the coated and textured ring/liner conjunction based on a thermal mixed lubrication model显示文摘For the ring/liner conjunction, well‐designed surface texturing has been regarded as a potential means to improve its tribological performance, as well as the application of coating. However, so far most researchers focused on the one of these aspects. In this study, the combined effect of coating and texturing on the performance of ring/liner conjunction is numerically investigated. A thermal mixed lubrication model is presented. The effects of the coating's thermal and mechanical properties on the tribological performance are studied under the cold and warm engine operating conditions. Along with the increasing coating thickness, the effects of the coating's thermal properties on friction loss are found to be significant, as well as the effects of the coating's mechanical properties. It is also found that a soft coating with a lower thermal inertia has a greater ability to reduce the friction loss of the textured conjunction. | Chunxing GU Xianghui MENG Di ZHANG | 2018 | Friction2018，6，4： | 7 |
| 13 | Micro/nano multiscale reinforcing strategies toward extreme high-temperature applications:Take carbon/carbon composites and their coatings as the examples显示文摘Carbon fiber reinforced carbon composites(C/Cs),are the most promising high-temperature materials and could be widely applied in aerospace and nucleation fields,owing to their superior performances.However,C/Cs are very susceptible to destructive oxidation and thus fail at elevated temperatures.Though matrix modification and coating technologies with Si-based and ultra-high temperature ceramics(UHTCs)are valid to enhance the oxidation/ablation resistance of C/Cs,it’s not sufficient to satisfy the increasing practical applications,due to the inherent brittleness of ceramics,mismatch issues between coatings and C/C substrates,and the fact that carbonaceous matrices are easily prone to high-temperature oxidation.To effectively solve the aforementioned problems,micro/nano multiscale reinforcing strategies have been developed for C/Cs and/or the coatings over the past two decades,to fabricate C/Cs with high strength and excellent high-temperature stability.This review is to systematically summarize the most recent major and important advancements in some micro/nano multiscale strategies,including nanoparticles,nanowires,carbon nanotubes/fibers,whiskers,graphene,ceramic fibers and hybrid micro/nano structures,for C/Cs and/or the coatings,to achieve high-temperature oxidation/ablation-resistant C/Cs.Finally,this review is concluded with an outlook of major unsolved problems,challenges to be met and future research advice for C/Cs with excellent comprehensive mechanical-thermal performance.It’s hoped that a better understanding of this review will be of high scientific and industrial interest,since it provides unusual and feasible new ideas to develop potential and practical C/Cs with improved high-temperature mechanical and oxidation/ablation-resistant properties. | Qiangang Fu Pei Zhang Lei Zhuang Lei Zhou Jiaping Zhang Jie Wang Xianghui Hou Ralf Riedel Hejun Li | 2022 | Journal of Materials Science & Technology2022，，1： | 7 |
| 14 | Characterization of Carotenoid Accumulation and Carotenogenic Gene Expression During Fruit Development in Yellow and White Loquat Fruit显示文摘Accumulation of carotenoids in peel and pulp of the yellow-fleshe loquat ‘Zaozhong 6'(ZZ6) and the white-fleshe loquat ‘Baiyu'(BY) were tracked during different fruit development stages, and the expression of 15 carotenogenic genes were analyzed. During loquat fruit ripening the fresh weight content of β-carotene in peel and pulp of ZZ6 increased gradually and peaked at the fully ripe stage, reaching 68.53 μg·g^(-1)FW in the peel and 11.92 μg·g^(-1)FW in the pulp. In BY, the content of β-carotene in the peel increased and peaked at the fully ripe stage, reaching38.89 μg·g^(-1)FW, while it decreased in the pulp from the original 0.47 μg·g~(^(-1))FW and reduced to 0.29 μg·g~(^(-1))FW. The content of β-cryptoxanthin in the peel and pulp of ZZ6 and BY both increased steadily, and peaked at the fully ripe stage; however, the content of lutein decreased in the peel of ZZ6 and increased in the pulp, but in BY, it dropped and then rose in the peel. There was no significan change of β-cryptoxanthin in the pulp of BY. After the breaker stage, the m RNA levels of phytoene synthase(PSY) and chromoplast-specifi lycopene β-cyclase(CYCB) were higher in the peel, while CYCB and β-carotene hydroxylase(BCH) m RNAs were higher in the fles of ZZ6, compared with BY. The results showed that the expression level of PSY, CYCB, and BCH appeared to cooperatively regulate the accumulation of carotenoids. | ZHANG Ling ZHANG Zhike ZHENG Tingting WEI Weilin ZHU Yunmei GAO Yongshun YANG Xianghui LIN Shunquan | 2016 | Horticultural Plant Journal2016，2，1： | 6 |
| 15 | Polypeptide dendrimers: Self-assembly and drug delivery显示文摘Amphiphilic dendritic poly(glutamic acid)-b-polyphenylalanine copolymers were synthesized using generation 3 dendritic poly(glutamic acid) as the macroinitiator in the ring-opening polymerization of NCA-Phe.The block copolymers self-assembled micelles with polyphenylalanine segments as core and dendritic poly(glutamic acid) segments as shell.The biocompatibility of the micelles was studied.The release of the anticancer drug doxorubicin from the micelles was investigated in vitro.The results showed that the sustaining release of the drug could last for 60 h.The micellar drug release system was efficient in inhibiting the proliferation of HepG2 liver cancer cells,75% cancer cells were killed under appropriate in vitro incubation. | XU XiangHui LI CaiXia LI HaiPing LIU Rong JIANG Chao WU Yao HE Bin GU ZhongWei | 2011 | Science China Chemistry2011，54，2： | 6 |
| 16 | CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta,alpha,beta,and gamma显示文摘SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape,compromising the effectiveness of existing vaccines and neutralizing antibodies.An in-depth investigation on COVID-19 pathogenesis is urgently needed to develop a strategy against SARS-CoV-2 variants.Here,we identified CD147 as a universal receptor for SARS-CoV-2 and its variants.Meanwhile,Meplazeumab,a humanized anti-CD147 antibody,could block cellular entry of SARS-CoV-2 and its variants-alpha,beta,gamma,and delta,with inhibition rates of 68.7,75.7,52.1,52.1,and 62.3%at 60μg/ml,respectively.Furthermore,humanized CD147 transgenic mice were susceptible to SARS-CoV-2 and its two variants,alpha and beta.When infected,these mice developed exudative alveolar pneumonia,featured by immune responses involving alveoli-infiltrated macrophages,neutrophils,and lymphocytes and activation of IL-17 signaling pathway.Mechanistically,we proposed that severe COVID-19-related cytokine storm is induced by a'spike protein-CD147-CyPA signaling axis':Infection of SARS-CoV-2 through CD147 initiated the JAK-STAT pathway,which further induced expression of cyclophilin A(CyPA);CyPA reciprocally bound to CD147 and triggered MAPK pathway.Consequently,the MAPK pathway regulated the expression of cytokines and chemokines,which promoted the development of cytokine storm.Importantly,Meplazumab could effectively inhibit viral entry and inflammation caused by SARS-CoV-2 and its variants.Therefore,our findings provided a new perspective for severe COVID-19-related pathogenesis.Furthermore,the validated universal receptor for SARS-CoV-2 and its variants can be targeted for COVID-19 treatment. | Jiejie Geng Liang Chen Yufeng Yuan Ke Wang Youchun Wang Chuan Qin Guizhen Wu Ruo Chen Zheng Zhang Ding Wei Peng Du Jun Zhang Peng Lin Kui Zhang Yongqiang Deng Ke Xu Jiangning Liu Xiuxuan Sun Ting Guo Xu Yang Jiao Wu Jianli Jiang Ling Li Kun Zhang Zhe Wang Jing Zhang Qingguo Yan Hua Zhu Zhaohui Zheng Jinlin Miao Xianghui Fu Fengfan Yang Xiaochun Chen Hao Tang Yang Zhang Ying Shi Yumeng Zhu Zhuo Pei Fei Huo Xue Liang Yatao Wang Qingyi Wang Wen Xie Yirong Li Mingyan Shi Huijie Bian Ping Zhu Zhi-Nan Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 6 |
| 17 | Fabrication of Bionic Superhydrophobic Manganese Oxide/Polystyrene Nanocomposite Coating显示文摘 | Xianghui Xu Zhaozhu Zhang Fang Guo Jin Yang Xiaotao Zhu Xiaoyan Zhou Qunji Xue | 2012 | Journal of Bionic Engineering2012，9，1： | 5 |
| 18 | In vitro and in vivo biocompatibility of Mg–Zn–Ca alloy operative clip显示文摘At present,titanium(Ti)and its alloys are most commonly use in hemostasis clip clinical applications.However,the Ti Clip cannot be absorbed in human body and produce artifacts on computed tomography(CT),and induce clinically relevant hypersensitivity in patients.In order to overcome the drawbacks of the non-degradable Ti clips,an Mg-Zn-Ca alloy operative clip was fabricated by combining hot extrusion and blanking processing.In vitro and in vivo biocompatibility of Mg-Zn-Ca alloy operative clip were evaluated by L-929 Cells and SD rat model respectively.It was found that Mg-Zn-Ca alloy exhibited non-cytotoxic to L929 cells.In vivo implantation showed that the newly designed Mg-Zn-Ca clip can successfully ligated carotid artery and no blood leakage occurred post-surgery.During the period of the clip degradation,a small amount of H2 gas formation and no tissue inflammation around the clips were observed.The degradation rate of the clip near the heart ligated the arteries faster than that of clip far away the heart due do the effect of arterial blood.Histological analysis and various blood biochemical parameters in rat serum samples collected at different times after clip implantation showed no tissue inflammation around the clips. | Pengfei Ding Yuanchao Liu Xianghui He Debao Liu Minfang Chen | 2019 | Bioactive Materials2019，4，1： | 5 |
| 19 | Devonian Sequence Stratigraphy and Relative Sea Level Changes in Longmenshan Area, Sichuan显示文摘The Longmenshan area is located at the western margin of Yangtze platform, where the Devonian is composed of clastic rocks, mixed clastic-carbonate rocks and carbonate rocks in ascending order, and was formed in the marine environment from nearshore to outer shelf. Based on a study of six sections the Devonian in Longemenshan area is divided into 18 sequences and 5 sequence sets. The maximum transgressive high in the Devonian of this area occurred in Early Frasnian, corresponding to asymmetricus zone. The boundaries among the sequence sets are roughly corresponding to the bottom boundaries of Ⅰa’,Ⅰc’,Ⅱa, and Ⅱd in the Devonian of West Europe and North America, respectively. The frequencies of the relative sea level changes in this area vary in different periods, but can be correlated with those in the other regions of the world. | Liu Wenjun Chen Yuanren Zheng Rongcai Wang Hongfeng Li Xianghui (Chengdu Institute of Technology, Chengdu 610059) | 1996 | Journal of Earth Science1996，15，1： | 5 |
| 20 | Control System Development and Experimental Study on Ultrasonic Vibration Feeding显示文摘Ultrasonic vibration feeding(UVF) method which can quantitatively feed and precisely deposit fine powder is a potential technique for micro feeding.The excitation sources transmit vibration to capillary though the third medium for most UVF devices.The vibrator is directly touched with the capillary can transmit mechanical energy on the capillary as much as possible,and the powder feeding can be controlled more precise.However,there are few reports about it.A direct UVF system which integrates the function of micro feeding,process observing,and powder forming was developed in this work.In order to analyze the effect of the system factors on feeding,a group of L9(33) orthogonal experiments are selected to confirm the effect of level change of factors.The three factors are capillary nozzle diameter,amplitude and signal.The flow rate was stable for each combined factors,and the optimum combination for the minimum flow rate are choosing small capillary,small amplitude,and triangular wave orderly.The whole process of feeding includes start point,middle stage and stop stage.Starting of feeding was synchronized to vibration when the amplitude of capillary nozzle is larger than critical amplitude.Then,the feeding process enters the middle stage,the feeding state is observed by the CCD,and it is very stable in the middle stage.Overflow of feeding can't be eliminated during the stop stage.The features of the deposited powder lines are analyzed;the overflow can be diminished by choosing small capillary and appropriate ratio of the capillary nozzle diameter to the particle size.Chinese characters lattices were deposited to validate the ability of quantitatively feeding and fixed feeding of UVF.Diameters of all powder dots show normal distribution,and more than 60% dots are concentrated from 550 μm to 650 μm,and the average diameter for all the dots is 597 μm.Most dots positions are well approached to their scheduled positions,and the maximum deviation is 0.27 mm.The new direct UVF system is used to implement experiments,which confirms the precise controllable of feeding.According improve the feeding technique,it suits well for rapid prototyping,chemistry,pharmaceutics and many other fields,which require precise measurement and feed minim powder. | ZENG Xianghui QI Lehua HUANG Hua LI Yang YANG Fang | 2011 | Chinese Journal of Mechanical Engineering2011，24，6： | 5 |
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