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| 1 | Removal of ammonium ion from water by Na-rich birnessite:Performance and mechanisms显示文摘Na-rich birnessite(NRB) was synthesized by a simple synthesis method and used as a high-efficiency adsorbent for the removal of ammonium ion(NH+4) from aqueous solution.In order to demonstrate the adsorption performance of the synthesized material,the effects of contact time,pH,initial ammonium ion concentration,and temperature were investigated.Adsorption kinetics showed that the adsorption behavior followed the pseudo second-order kinetic model.The equilibrium adsorption data were fitted to Langmuir and Freundlich adsorption models and the model parameters were evaluated.The monolayer adsorption capacity of the adsorbent,as obtained from the Langmuir isotherm,was 22.61 mg NH+4-N/g at283 K.Thermodynamic analyses showed that the adsorption was spontaneous and that it was also a physisorption process.Our data revealed that the higher NH+4adsorption capacity could be primarily attributed to the water absorption process and electrostatic interaction.Particularly,the high surface hydroxyl-content of NRB enables strong interactions with ammonium ion.The results obtained in this study illustrate that the NRB is expected to be an effective and economically viable adsorbent for ammonium ion removal from aqueous system. | Ya Cheng Tinglin Huang Xinxin Shi Gang Wen Yuankui Sun | 2017 | Journal of Environmental Sciences2017，29，7： | 12 |
| 2 | Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of immunotherapy response显示文摘Personalized immunotherapy targeting tumor-specific antigens(TSAs)could generate efficient and safe antitumor immune response without damaging normal tissues.Although neoantigen vaccines have shown therapeutic effect in clinic trials,precise prediction of neoantigens from tumor mutations is still challenging.The host antitumor immune response selects and activates T cells recognizing tumor antigens.Hence,T cells engineered with T-cell receptors(TCRs)from these naturally occurring tumor antigen-specific T(Tas)cells in a patient will target personal TSAs in his/her tumor.To establish such a personalized TCR-T cell therapy,we comprehensively characterized T cells in tumor and its adjacent tissues by single-cell mRNA sequencing(scRNA-seq),TCR sequencing(TCR-seq)and in vitro neoantigen stimulation.Compared to bystander T cells circulating among tissues,Tas cells were characterized by tumor enrichment,tumor-specific clonal expansion and neoantigen specificity.We found that CXCL13 is a unique marker for both CD4^(+)and CD8^(+)Tas cells.Importantly,TCR-T cells expressing TCRs from Tas cells showed significant therapeutic effects on autologous patient-derived xenograft(PDX)tumors.Intratumoral Tas cell levels measured by CXCL13 expression precisely predicted the response to immune checkpoint blockade,indicating a critical role of Tas cells in the antitumor immunity.We further identified CD200 and ENTPD1 as surface markers for CD4^(^(+))and CD8^(^(+))Tas cells respectively,which enabled the isolation of Tas cells from tumor by Fluorescence Activating Cell Sorter(FACS)sorting.Overall,our results suggest that TCR-T cells engineered with Tas TCRs are a promising agent for personalized immunotherapy,and intratumoral Tas cell levels determine the response to immunotherapy. | Jingjing He Xinxin Xiong Han Yang Dandan Li Xuefei Liu Shuo Li Shuangye Liao Siyu Chen Xizhi Wen Kuai Yu Lingyi Fu Xingjun Dong Kaiyu Zhu Xiaojun Xia Tiebang Kang Chaochao Bian Xiang Li Haiping Liu Peirong Ding Xiaoshi Zhang Zhenjiang Liu Wende Li Zhixiang Zuo Penghui Zhou | 2022 | Cell Research2022，32，6： | 10 |
| 3 | Discriminated sgRNAs-Based SurroGate System Greatly Enhances the Screening Efficiency of Plant Base-Edited Cells显示文摘The development of CRISPR/Cas9-mediated base editing has made genomic modification more efficient. However, selection of genetically modified cells from millions of treated cells, especially plant cells, is still challenging. In this study, an efficient surrogate reporter system based on a defective hygromycin resistance gene was established in rice to enrich base-edited cells. After step-by-step optimization, the Discriminated sgRNAs-based SurroGate system (DisSUGs) was established by artificially differentiating the editing abilities of a wild-type single guide RNA (sgRNA) targeting the surrogate reporter gene and an enhanced sgRNA targeting endogenous sites. The DisSUGs enhanced the efficiency of screening base-edited cells by 3- to 5-fold for a PmCDA1-based cytosine-to-tyrosine base editor (PCBE), and 2.5- to 6.5-fold for an adenine base editor (ABE) at endogenous targets. These targets showed editing efficiencies of <25% in the conventional systems. The DisSUGs greatly enhanced the frequency of homozygous substitutions and expanded the activity window slightly for both a PCBE and an ABE. Analyses of the total number of single-nucleotide variants from whole-genome sequencing revealed that, compared with the no-enrichment PCBE strategy, the DisSUGs did not alter the frequency of genome-wide sgRNA-independent off-target mutations, but slightly increased the frequency of target-dependent off-target mutations. Collectively, the DisSUGs developed in this study greatly enhances the efficiency of screening plant base-edited cells and will be a useful system in future applications. | Wen Xu Yongxing Yang Ya Liu Guiting Kang Feipeng Wang Lu Li Xinxin Lv Si Zhao Shuang Yuan Jinling Song Ying Wu Feng Feng Xiaoqing He Chengwei Zhang Wei Song Jiuran Zhao Jinxiao Yang | 2020 | Molecular Plant2020，13，1： | 8 |
| 4 | Covalent organic frameworks derived hollow structured N-doped noble carbon for asymmetric-electrolyte Zn-air battery显示文摘We report a relatively low-temperature molten salt strategy to prepare hollow structured N-doped noble carbon(h-NNC) with highly desirable features of ultra-large surface area(1957 m^2 g^(-1)) and high graphitization, endowing the h-NNC with high activity toward catalysis of oxygen reduction reaction in acidic medium. The h-NNC is applied as cathode catalyst of an asymmetrical-electrolyte Zn-air battery, which exhibits an open circuit voltage of 2.11 V, a power density up to 270 mW cm^(-2),and an energy density of 1279 W h kg^(-1), behaving advantages over the conventional Zn-air batteries. | Pingwei Cai Xinxin Peng Junheng Huang Jingchun Jia Xiang Hu Zhenhai Wen | 2019 | Science China Chemistry2019，62，3： | 6 |
| 5 | Genetic variations in plant architecture traits in cotton(Gossypium hirsutum) revealed by a genomewide association study显示文摘Plant architecture traits influence crop yield. An understanding of the genetic basis of cotton plant architecture traits is beneficial for identifying favorable alleles and functional genes and breeding elite cultivars. We collected 121 cotton accessions including 100 brownfiber and 21 white-fiber accessions, genotyped them by whole-genome resequencing, and phenotyped them in multiple environments. This genome-wide association study(GWAS)identified 11 quantitative trait loci(QTL) for two plant architecture traits: plant height and fruit spur branch number. Negative-effect alleles were enriched in the elite cultivars. Based on these QTL, gene annotation information, and published QTL, candidate genes and natural genetic variations in four QTL were identified. Ghir_D02 G017510 and Ghir_D02 G017600 were identified as candidate genes for qD02-FSBN-1, and a premature start codon gain variation was found in Ghir_D02 G017510. Ghir_A12 G026570, the candidate gene of qA12-FSBN-2, belongs to the pectin lyase-like superfamily, and a significantly associated SNP, A12_105366045(T/C), in this gene represents an amino acid change. The QTL, candidate genes, and associated natural variations in this study are expected to lay a foundation for studying functional genes and developing breeding programs for desirable architecture in brown-fiber cotton. | Tianwang Wen Baosheng Dai Tao Wang Xinxin Liu Chunyuan You Zhongxu Lin | 2019 | The Crop Journal2019，7，2： | 4 |
| 6 | LabVIEW-based auto-timing counts virtual instrument system with ORTEC 974 Counter/Timer显示文摘In order to achieve the auto-timing counts measurement of nuclear radiation using ORTEC 974 Counter/Timer, an auto-timing counts virtual instrument system based on the LabVIEW virtual instrument development platform and GPIB instrument control and transmission bus protocol is designed in this paper. By introducing software timing technique, the minimum time base of factory setting improves from 0.1 s to 0.03 s. The timing counts performance and longtime stability are also discussed in detail. The automatic data recording and saving facilitates data analysis and processing. Its real-time display and statistic function is very convenient for monitoring the nuclear radiation. | YAN Jie LIU Rong LI Cheng JIANG Li LU Xinxin ZHU Tonghua WANG Mei WEN Zhongwei LIN Jufang | 2009 | Nuclear Science and Techniques2009，20，5： | 2 |
| 7 | Reaction rates in blanket assemblies of a fusion-fission hybrid reactor显示文摘To validate neutronics calculation for the blanket design of fusion-fission hybrid reactor,experiments for measuring reaction rates inside two simulating assemblies are performed.Two benchmark assemblies were developed for the neutronics experiments.A D-T fusion neutron source is placed at the center of the setup.One of them consists of three layers of depleted uranium shells and two layers of polyethylene shells,and these shells are arranged alternatively.The ^(238)U capture reaction rates are measured using depleted uranium foils and an HPGe gamma spectrometer.The fission reaction rates are measured using a fission chamber coated with depleted uranium.The other assembly consists of depleted uranium and LiH shells.The tritium production rates are measured using the lithium glass scintillation detector which is placed in the LiH region of the assembly.The measured reaction rates are compared with the calculated ones predicted using MCNP code,and C/E values are obtained. | LIU Rong ZHU Tonghua YAN Xiaosong WANG Xinhua LU Xinxin JIANG Li WANG Mei WEN Zhongwei HAN Zijie LIN Jufan YANGYiwei | 2012 | Nuclear Science and Techniques2012，23，4： | 2 |
| 8 | A novel spoof surface plasmon polariton structure to reach ultra-strong field confinements显示文摘Ultrathin corrugated metallic structures have been proved to support spoof surface plasmon polariton (SPP) modes on two-dimension (2D) planar microwave circuits.However,to provide stronger field confinement,larger width of strip is required to load deeper grooves,which is cumbersome in modern large-scale integrated circuits and chips.In this work,a new spoof SPP transmission line (TL) with zigzag grooves is proposed.This new structure can achieve stronger field confinement compared to conventional one with the same strip width.In other words,the proposed spoof SPP TL behaves equivalently to a conventional one with much larger size.Dispersion analysis theoretically indicates the negative correlation between the ability of field confinement and cutoff frequencies of spoof SPP TLs.Numerical simulations indicate that the cutoff frequency of the proposed TL is lower than the conventional one and can be easily modified with the fixed size.Furthermore,two samples of the new and conventional spoof SPP TLs are fabricated for experimental demonstration.Measured S-parameters and field distributions verify the ultra-strong ability of field confinement of the proposed spoof SPP TL.Hence,this novel spoof SPP structure with ultra-strong field confinement may find wide applications in microwave and terahertz engineering. | Pei Hang He Hao Chi Zhang Xinxin Gao Ling Yun Niu Wen Xuan Tang Jiayuan Lu Le Peng Zhang Tie Jun Cui | 2019 | Opto-Electronic Advances2019，2，6： | 2 |
| 9 | WoT/SDN:Web of Things Architecture Using SDN显示文摘Wo T(Web of Things) integrates smart devices into Web by reusing and extending Web standards. While Web technology makes the developers' job easier,it faces security,management and efficiency challenges. We propose Wo T/SDN,the architecture of resource oriented Wo T built on SDN(Software Defined Network),in which applications could be developed through resource subscription and Mashup with the programmability provided by SDN. The key components are designed,including Security and Management Controller(SMC),various atomic services and resource subscription syntax. Three applications covering device management,data access and security protection are demonstrated. Compared to traditional resource-oriented Wo T systems,our test results show that SDN,with its logically centralized control capability and awareness of flow forwarding,provides new opportunity to improve performance,simplify management and enhance security for Wo T. | QIU Xiaofeng LIU Wenmao GAO Teng HE Xinxin WEN Xutao CHEN Pengcheng | 2015 | China Communications2015，12，11： | 2 |
| 10 | Recent Advances of Transition Metal Basic Salts for Electrocatalytic Oxygen Evolution Reaction and Overall Water Electrolysis显示文摘Electrocatalytic oxygen evolution reaction(OER)has been recognized as the bottleneck of overall water splitting,which is a promising approach for sustainable production of H_(2).Transition metal(TM)hydroxides are the most conventional and classical non-noble metal-based electrocatalysts for OER,while TM basic salts[M^(2+)(OH)_(2-x)(A_(m^(-))_(x/m),A=CO_(3)^(2−),NO_(3)^(−),F^(−),Cl^(−)]consisting of OH−and another anion have drawn extensive research interest due to its higher catalytic activity in the past decade.In this review,we summarize the recent advances of TM basic salts and their application in OER and further overall water splitting.We categorize TM basic salt-based OER pre-catalysts into four types(CO_(3)^(2−),NO_(3)^(−),F^(−),Cl^(−)according to the anion,which is a key factor for their outstanding performance towards OER.We highlight experimental and theoretical methods for understanding the structure evolution during OER and the effect of anion on catalytic performance.To develop bifunctional TM basic salts as catalyst for the practical electrolysis application,we also review the present strategies for enhancing its hydrogen evolution reaction activity and thereby improving its overall water splitting performance.Finally,we conclude this review with a summary and perspective about the remaining challenges and future opportunities of TM basic salts as catalysts for water electrolysis. | Bingrong Guo Yani Ding Haohao Huo Xinxin Wen Xiaoqian Ren Ping Xu Siwei Li | 2023 | Nano-Micro Letters2023，15，4： | 2 |
| 11 | Multiplexed cytokine profiling of serum for detection of colorectal cancer显示文摘 | Zhang Pengjun Wen Xinyu Gu Feng Deng Xinxin Liu Yulan Li Juan Jia Xingwang Dong Zhennan Tian Yaping | 2013 | Future Oncol2013，，7： | 2 |
| 12 | Expression,characteriza-tion,and preliminary X-ray crystallographic analysis of recombinant murine Follistatin-like 1 expressed in Drosophila $2 cells 显示文摘 | Lian Li Xinxin Li Xue Liu Wen Ning | 2013 | BioSeienee Trends2013，7，2： | 1 |
| 13 | Nondestructive detection of brown core in the Chinese pear ‘Yali’ by transmission visible–NIR spectroscopy显示文摘 | Donghai Han Runlin Tu Chao Lu Xinxin Liu Zhaohui Wen | 2005 | Food Control2005，，8： | 1 |
| 14 | Human Plague Case Diagnosed in Ningxia Tracked to Animal Reservoirs—Inner Mongolia Autonomous Region,China,2021显示文摘Summary What is already known about this topic?There were a total of 4 and 3 human plague cases that occurred in the Inner Mongolia Autonomous Region in 2019 and 2020,respectively,with 1 and 2 deaths in 2019 and 2020 respectively,which indicated that plague still poses a significant threat to human health especially for farmers,shepherds,or residents living in native plague foci.What is added by this report?On August 14,2021,1 patient from the Otog Qi(County)in the Inner Mongolia sought treatment in Yinchuan City(the capital of Ningxia Hui Autonomous Region). | Jianwei Gao Yanhong Hu Cheng Ju Jingyuan Liu Yiting Wang Jiangtao Ma Xiaona Shen Fang Liu Jin Guo Xinxin Yu Wen Zhang Shuyi Wang Kun Li Zhongbing Zhang Biao Kan Wenrui Wang Xianbin Cong Mengguang Fan Wei Li Kuidong Shao Tao Zhang Jianyun Li Yumeng Wang | 2021 | China CDC weekly2021，3，52： | 1 |
| 15 | Association of C-reactive protein and metabolic syndrome in a rural Chinese population显示文摘 | Jiangping Wen Yuanbo Liang Fenghua Wang Lanping Sun Yongjun Guo Xinrong Duan Xiangyi Liu Qiushan Tao Tien Yin Wong Xinxin Lu Ningli Wang | 2009 | Clinical Biochemistry2009，，10： | 1 |
| 16 | Extraction of straight field roads between farmlands based on agricultural vehicle-mounted LiDAR显示文摘The application of autonomous agricultural vehicles is gaining popularity as a way to increase production efficiency and lower operational costs.To achieve high performance,perception tasks(such as obstacle detection,road extraction,and drivable area extraction)are of great importance.Compared with structured roads,field roads between farmlands,including unstructured roads and semi-structured roads,are unfavorable for autonomous agricultural vehicle driving due to their bumpiness and unstructured nature.This study proposed an extraction method for the straight field roads between farmlands.The proposed method was based on the point cloud data acquired by LiDAR(Velodyne VLP-16)mounted on a John Deere 12046B-1204 tractor.The proposed method has three aspects:Euclidean Clustering-based extraction,boundary-based extraction,and road point cloud curve segment modification.Firstly,Euclidean Clustering with K-Dimensional(KD)-Tree data structure was adopted to extract the road curve segments close to the LiDAR composed of road points.Secondly,the boundary lines constraint was constructed to extract the distant road curve segments.Thirdly,the local distance ratio was used to modify the extracted road curve segments.The average extraction accuracy for both semi-structured and unstructured roads exceeded 98%,and the false positive rate(FPR)was less than 0.5%.These experimental findings demonstrated that the proposed road extraction method was precise and effective.The proposed method of this study can be applied to enhance the perception ability of autonomous agricultural vehicles thereby increasing the efficiency and safety of field road driving. | Lili Yang Yuanyuan Xu Yajie Liang Jia Qin Yuanbo Li Xinxin Wang Weixin Zhai Long Wen Zhibo Chen Caicong Wu | 2022 | International Journal of Agricultural and Biological Engineering2022，15，5： | 1 |
| 17 | Bioinspired zinc-mediated umpolung thiolation of alkyl electrophiles: reaction development, scope and mechanism显示文摘Zinc-promoted umpolung thiolation of alkyl electrophiles with masked sulfur transfer reagents in the absence of nickel or copper catalysis is described. This protocol proceeds via a SET process of Zn to electrophilic sulfur reagent followed by insertion of Zn into disulfide and nucleophilic thiolation, providing straightforward access to a wide range of alkyl sulfides with broad substrate scope. A neutral TMEDA-ligated four-coordinated zinc thiolate with tetrahedra geometry was synthesized, isolated and fully characterized by NMR, IR and X-ray analysis. More importantly, the chemical reactivity of this active intermediate has been investigated, enabling the construction of C-Se, C-Te, Sb-S and Bi-S bonds to prepare valuable sulfur-containing molecules and beyond. | Yuenian Xu Yan Zhang Yong Liu Wen-Wu Sun Jie Huang Hui He Yingjie Wu Wen Liu Shao-Fei Ni Xu-Qiong Xiao Xinxin Shao | 2024 | Science China Chemistry2024，67，3： | 0 |
| 18 | Tri-profit electrolysis for energy-efficient production of benzoic acid and H_(2)显示文摘Electrosynthesis has recently attracted intensive research attentions and holds great potential in implementing scalable green synthesis thanks to more and more readily accessible renewable electric energy. | Chi Zhang Suqin Ci Xinxin Peng Junheng Huang Pingwei Cai Yichun Ding Zhenhai Wen | 2021 | Journal of Energy Chemistry2021，30，3： | 0 |
| 19 | Solid-state Z-scheme assisted hydrated tungsten trioxide/ZnIn_(2)S_(4) photocatalyst for efficient photocatalytic H_(2) production显示文摘Efficient water splitting for H_(2) evolution over semiconductor photocatalysts is highly attractive in the field of clean energy.It is of great significance to construct heterojunctions,among which the direct Z-scheme nanocomposite photocatalyst provides effective separation of photo-generated carriers to boost the photocatalytic performance.Herein,Z-scheme hydrated tungsten trioxide/ZnIn_(2)S_(4) is fabricated via an in-situ hydrothermal method where ZnIn_(2)S_(4) nanosheets are grown on WO_(3)·xH_(2)O.The close contact between WO_(3)·0.5H_(2)O and WO_(3)·0.33H_(2)O as well as ZnIn_(2)S_(4) improve the charge carrier separation and migration in the photocatalyst,where the strong reducing electrons in the conduction band of ZnIn_(2)S_(4) and the strong oxidizing holes in the valence band of WO_(3)·0.33H_(2)O are retained,leading to enhanced photocatalytic hydrogen production.The obtained WO_(3)·xH_(2)O/ZnIn_(2)S_(4) shows an excellent H_(2) production rate of 7200μmol g^(−1) h^(−1),which is 11 times higher than pure ZnIn_(2)S_(4).To the best of our knowledge,this value is higher than most of the WO_(3)-based noble metal-free semiconductor photocatalysts.The improved stability and activity are attributed to the formation of the Z-scheme heterojunction,which can markedly accelerate the interfacial charge separation for surface reaction.This work offers a promising strategy towards the design of an efficient Z-scheme photocatalyst to suppress electron–hole recombination and optimize redox potential. | Lin Ye Xinxin Peng Zhenhai Wen Haitao Huang | 2022 | Materials Futures2022，1，3： | 0 |
| 20 | 'Green Drilling Rigs'Lead New Trends in the Traditional Energy Equipment Market显示文摘Recently,the 1500HP hybrid drilling rigs exported by China Petroleum Technology and Development Corporation(CPTDC)successfully commenced drilling in Abu Dhabi,United Arab Emirates(UAE).The Abu Dhabi Hybrid Drilling Rig Project,commemorating the 10th anniversary of China’s'Belt and Road'initiative,symbolizes CPTDC’s dedication to practical cooperation and sustainable development.It serves as a pioneering endeavor in global carbon emission reduction,aiming to elevate the developmental standards and improve the well-being of participating countries.This project propels the green and low-carbon transformation of China’s energy equipment sector,fostering its advancement into the international high-end market,thereby enhancing the prestige of the'Made in China'brand with positive contributions. | Cheng Wenping Wang Guangzhong Zhang Lei Yang Zhongxing Wen Liangfan Xu Xinxin Deng Shen | 2023 | China Oil & Gas2023，30，6： | 0 |
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