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| 1 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 2 | Effects of lead exposure on placental cellular apoptosis and endoplasmic reticulum stress in rats显示文摘 | Wang Yunying Hu Haiyan Li Hong Ma Haiyan Xu Fengsen Qu Baoming | 2014 | Chinese Medical Journal2014，，9： | 4 |
| 3 | Nonbinary LDPC cycle codes: efficient search,design, and code optimization显示文摘Nonbinary low-density parity-check (NBLDPC)codes have the ability of approaching capacitywhen decoded iteratively using a probabilistic de-coding algorithm. With the increase of the finitefield size q, NBLDPC codes over GF(q) have muchbetter performance under iterative decoding fora constant code length. | Hengzhou XU Chao CHEN Min ZHU Baoming BAI Bo ZHANG | 2018 | Science China(Information Sciences)2018，61，8： | 3 |
| 4 | Algebraic-Based Nonbinary LDPC Codes with Flexible Field Orders and Code Rates显示文摘In this paper, we study the rank of matrices over GF(2~p),and propose two construction methods for algebraic-based nonbinary LDPC codes from an existing LDPC code, referred to as the original code. By multiplying all elements of each column of the binary parity-check matrix H corresponding to the original code with the same nonzero element of any field, the first class of nonbinary LDPC codes with flexible field order is proposed. The second method is to replace the nonzero elements of some columns in H with different nonzero field elements in a given field, and then another class of nonbinary LDPC codes with various rates is obtained. Simulation results show that the proposed nonbinary LDPC codes perform well over the AWGN channel with the iterative decoding algorithms. | Hengzhou Xu Dan Feng Cheng Sun Baoming Bai | 2017 | China Communications2017，14，4： | 3 |
| 5 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells显示文摘 | Miguel Angel Esteban Tao Wang Baoming Qin Jiayin Yang Dajiang Qin Jinglei Cai Wen Li Zhihui Weng Jiekai Chen Su Ni Keshi Chen Yuan Li Xiaopeng Liu Jianyong Xu Shiqiang Zhang Feng Li Wenzhi He Krystyna Labuda Yancheng Song Anja Peterbauer Susanne Wolbank H | 2010 | Cell Stem Cell2010，，： | 3 |
| 6 | Synthesis of two lanthanide clusters Ln^(Ⅲ)_(4)(Gd_(4) and Dy_(4)) with [2×2] square grid shape:Magnetocaloric effect and slow magnetic relaxation behaviors显示文摘Two isostructural tetranuclear lanthanide clusters named [Ln_(4)(L)_(4)(CH_(3) O)_(4)]·CH_(3) OH(Ln=Gd(Ⅲ) for 1,Dy(Ⅲ) for 2,H_(2) L=N’-(2-hydroxy-3-methoxybenzylidene)-6-(hydroxymethyl) picolinohydrazide) were successfully isolated by using a polydentate Schiff based ligand and Ln(Ⅲ) nitrate salts.The structures of 1 and 2 were characterized by X-ray structural analyses,they are held by four double deprotonated ligands L2-.In them all the lanthanide ions are eight-coordinated and distributed over four vertices of a parallelogram,presenting a Ln4 cluster with a strict [2 × 2] square grid pattern.The details of magnetic analysis show that 1 displays weak anti-ferromagnetic exchange between neighboring Gd(Ⅲ) ions through carboxylate oxygen and methanol oxygen ligand atoms.Furthermore,1 exhibits significant magnetocaloric effect with the maximum entropy change-ΔSm value of 28.5 J/(kg K) for ΔH=7.0 T at 2.0 K.For compound 2,remarkable slow magnetic relaxation behaviors are observed in the presence of zero magnetic field with τ0=1.02 × 10^(-6) s and energy barrier ΔE/kB=43.24 K. | Chunying Xu Zhilei Wu Chenjuan Fan Lili Yan Wenmin Wang Baoming Ji | 2021 | Journal of Rare Earths2021，39，9： | 2 |
| 7 | Effects of ethanol extracts of scorpion on hippocampal apoptosis and caspase-3 expression in lithium chloride-pilocarpine-induced status epilepticus rats显示文摘BACKGROUND: Previous studies have demonstrated that scorpion venom in the scorpion can inhibit epilepsy and apoptosis.However,it remains unclear whether ethanol extracts of scorpion (EES) exhibit similar effects.OBJECTIVE: To investigate the effects of EES on hippocampal apoptosis and caspase-3 expression,and to compare the effects on sodium valproate (positive control drug) in a rat model of status epilepticus induced by lithium chloride-pilocarpine.DESIGN,TIME AND SETTING: This randomized,controlled study was conducted at the Drug Research and Development Center,Kanghong Pharmaceuticals Group,and the Department of Pathology,Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital,China from May 2007 to April 2008.MATERIALS: EES were prepared by Huashen Pharmaceutical,China.Sodium valproate (Hunan Xiangzhong Pharmaceutical,China) and lithium chloride-pilocarpine (Sigma,USA) were also used in the present study.METHODS: From a total of 156 rats,six served as normal controls.The remaining rats were intraperitoneally injected with lithium chloride-pilocarpine to establish status epilepticus models,and then assigned to five groups (n = 30,respectively).Animals in each group were administered drugs at 15 minutes after epileptic seizure by gavage.i.e.in the normal control and model groups,rats were treated with 1 mL/0.1 kg saline.The sodium valproate group was administered 120 mg/kg/d sodium valproate.The low-,moderate-,and high-dose EES groups received treatments of 290,580,and 1 160 mg/kg/d EES.The dispensed concentration was 1 mL/0.1 kg.Rat seizure behavior was observed.If status epilepticus did not terminated after 1 hour,the rats were intraperitoneally administered atropine (1 mg/kg) and diazepam (10 mg/kg) to terminate seizure.These rats were continuously observed for 6 hours to ensure seizure termination.Then rats were treated with the above-mentioned drugs at 8: 00 am each day until sacrifice,which took place 4 hours after drug administration.MAIN OUTCOME MEASURES: Terminal dUTP nick end labeling (TUNEL)-positive cells and caspase-3 expression were,respectively,determined by TUNEL and immunohistochemistry at 6,24,48,and 72 hours,as well as 7 days,after status epilepticus.Behavioral changes were also measured.RESULTS: A few caspase-3-positive cells were observed.TUNEL-and caspase-3-positive cells were mainly visible in the hippocampal CA1 and CA3 regions 6 hours following status epilepticus in the model and drug intervention groups.The number of TUNEL-positive cells reached a peak at 48 hours following status epilepticus in the sodium valproate group,as well as the moderate-and high-dose EES groups,and number of TUNEL-positive cells reached a peak at 72 hours in the model and low-dose EES groups.The number of caspase-3-positive cells reached a peak at 48 hours in each group.Following treatment of sodium valproate and EES,the number of TUNEL-and caspase-3-positive cells significantly decreased compared with the model group at various time points (P < 0.05).The number of TUNEL-and caspase-3-positive cells was greatest in the low-dose EES group,followed by the moderate-and high-dose EES groups.The number of TUNEL-and caspase-3-positive cells was similar between the sodium valproate and high-dose EES groups.Epileptic seizure was significantly improved in the sodium valproate group,as well as the moderate-and high-dose EES groups,compared with the model group (P < 0.05 or P < 0.01).Treatment with sodium valproate and high-dose EES resulted in the best outcome,although the results were similar (P > 0.05).CONCLUSION: A dose of 1 160 mg/kg/d EES significantly inhibited status epilepticus.This outcome corresponded to a decreased number of apoptotic cells and caspase-3-positive cells,which was similar to sodium valproate.These results suggest that it is not necessary to extract a component from the scorpion for the treatment of epilepsy.The high dose of EES significantly inhibited epilepsy,which correlated with decreased hippocampal caspase-3 expression. | Liang Yu Hongbin Sun Yi Liang Yan Xie Baoming He Fei Xu | 2010 | Neural Regeneration Research2010，5，2： | 2 |
| 8 | Application of tobacco stems briquetting in tobacco flue-curing in rural area of China显示文摘To reduce the conventional energy consumption in rural area of China,tobacco stems briquetting(TSB)was used as fuel during the process of tobacco flue-curing,compared with honeycomb briquette(HB).Three fire furnaces with different heat exchangers using TSB were compared using the tobacco flue-curing.The results showed that the smog temperature of TSB was higher than that of HB,the efficiency of bio-fuel system with TSB was from 43.5%to 54%,while the efficiency of traditional fuel system was 51.5%.And the cost of tobacco flue-curing per hectare with TSB and HB was$750.0 and$1282.5,respectively.It is proved that TSB is an alternative choice using for the industry of tobacco flue-curing,and the improvement in the structure of fire furnace could optimize the process of tobacco flue-curing. | Wang Xinfeng Xu Guizhuan Zhang Bailiang Jiao Youzhou Lu Haifeng Li Baoming | 2015 | International Journal of Agricultural and Biological Engineering2015，8，6： | 2 |
| 9 | Metal-organic frameworks derived flower-like Co_3O_4/nitrogen doped graphite carbon hybrid for high-performance sodium-ion batteries显示文摘In this work, a novel flower-like cobalt-based metal organic frameworks(MOFs) self-assembled by Co^(2+) and nicotinic acid have been designed and synthesized. After a simple annealing treatment, Co_3O_4 nanoparticles in-situ decorating on nitrogen doped graphite carbon-sheet(Co_3O_4/NC) were obtained. The resultant Co_3O_4/NC hybrid with unique flower-like structure and ration combination of Co_3O_4 nanoparticles and nitrogen doped graphite carbon, endowing the hybrid with enhanced electrical conductivity,short ion diffusion pathways and rich porosity to the materials, which can largely alleviate the problems of Co_3O_4 such as inferior intrinsic electrical conductivity, sluggish ion kinetics and large volume change upon cycling. When evaluated as anode material for sodium-ion batteries(SIBs), the Co_3O_4/NC hybrid exhibits satisfied reversible capacity(213.9 mAh g^(-1) after 100 cycles at 0.1 A g^(-1) ), excellent rate capability(145.4 m Ah g^(-1) at 2 A g^(-1) and 130.1 mAh g^(-1) at 4 A g^(-1) ) and robust long-term cycling stability(120.1 m Ah g^(-1) after 2000 cycles at 0.5 A g^(-1) ), showing great potential for high-performance SIBs. | Haifeng Xu Guang Zhu Baoming Hao | 2019 | Journal of Materials Science & Technology2019，35，1： | 2 |
| 10 | Unimodal productivity-biodiversity relationship along the gradient of multidimensional resources across Chinese grasslands显示文摘Resources can affect plant productivity and biodiversity simultaneously and thus are key drivers of their relationships in addition to plant-plant interactions.However,most previous studies only focused on a single resource while negle cting the nature of resource multidimensionality.Here we integrated four essential resources for plant growth into a single metric of resource diversity(RD)to investigate its effects on the productivity-biodiversity relationship(PBR)across Chinese grasslands.Results showed that habitats differing in RD have different PBRs—positive in low-resource habitats,but neutral in medium-and high-resource ones—while collectively,a weak positive PBR was observe d.However,when excluding direct effects of RD on productivity and biodiversity,the PBR in high-resource habitats became negative,which leads to a unimodal instead of a positive PBR along the RD gradient.By integrating resource effects and changing plant-plant interactions into a unified framework with the RD gradient,our work contributes to uncovering underlying me chanisms for inconsistent PBRs at large scales. | Yanfen Wang Jianqing Du Zhe Pang Yali Liu Kai Xue Yann Hautier Biao Zhang Li Tang Lili Jiang Baoming Ji Xingliang Xu Jing Zhang Ronghai Hu Shutong Zhou Fang Wang Rongxiao Che Di Wang Chaoting Zhou Xiaoyong Cui Nico Eisenhauer Yanbin Hao | 2022 | National Science Review2022，9，12： | 2 |
| 11 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells显示文摘 | Miguel Angel Esteban Tao Wang Baoming Qin Jiayin Yang Dajiang Qin Jinglei Cai Wen Li Zhihui Weng Jiekai Chen Su Ni Keshi Chen Yuan Li Xiaopeng Liu Jianyong Xu Shiqiang Zhang Feng Li Wenzhi He Krystyna Labuda Yancheng Song Anja Peterbauer Susanne Wolbank H | 2010 | Cell Stem Cell2010，，1： | 1 |
| 12 | Microalgae cultivation and culture medium recycling by a two-stage cultivation system显示文摘Nutrients and water play an important role in microalgae cultivation.Using wastewater as a culture medium is a promising alternative to recycle nutrients and water,and for further developing microalgae-based products.In the present study,two species of microalgae,Chlorella sp.(high ammonia nitrogen tolerance)and Spirulinaplatensis (S.platensis,high growth rate),were cultured by using poultry wastewater through a two-stage cultivation system for algal biomass production.Ultrafiltration (UF)or centrifuge was used to harvest Chlorella-sp.from the first cultivation stage and to recycle culture medium for S.platensis growth in the second cultivation stage.Results showed the two-stage cultiyation system produced high microalgae biomass including 0.39g·L^-1 Chlorella sp.and 3.45g·L^-1 S.platensis in the first-stage and second-stage,respectively.In addition,the removal efficiencies of NH4+reached 19% and almost 100% in the first and the second stage,respectively. Total phosphorus (TP)removal reached 17% and 83%,and total organic carbon (TOC)removal reached 55% and 72% in the first and the second stage,respectively.UF and centrifuge can reeycle 96.8% and 100% water,respectively.This study provides a new method for the combined of pure microalgae cultivation and wastewater treatment with eulture medium recycling. | Xinfeng Wang Lu Lin Haifeng Lu Zhidan Liu Na Duan Taili Dong Hua Xiao Baoming Li Pei Xu | 2018 | Frontiers of Environmental Science & Engineering2018，12，6： | 1 |
| 13 | Bridging the structure gap between pellets in artificial dissolution media and in gastro-intestinal tract in rats显示文摘Changes in structure of oral solid dosage forms(OSDF) elementally determine the drug release and its therapeutic effects.In this research,synchrotron radiation X-ray micro-computed tomography was utilized to visualize the 3 D structure of enteric coated pellets recovered from the gastrointestinal tract of rats.The structures of pellets in solid state and in vitro compendium media were measured.Pellets in vivo underwent morphological and structural changes which differed significantly from those in vitro compendium media.Thus,optimizations of the dissolution media were performed to mimic the appropriate in vivo conditions by introducing pepsin and glass microspheres in media.The sphericity,pellet volume,pore volume and porosity of the in vivo esomeprazole magnesium pellets in stomach for2 h were recorded 0.47,1.55 × 10^(8)μm^(3),0.44 × 10^(8)μm^(3)and 27.6%,respectively.After adding pepsin and glass microspheres,the above parameters in vitro reached to 0.44,1.64 × 10^(8)μm^(3)0.38 × 10^(8)μm^(3)and 23.0%,respectively.Omeprazole magnesium pellets behaved similarly.The structural features of pellets between in vitro media and in vivo condition were bridged successfully in terms of 3 D structures to ensure better design,characterization and quality control of advanced OSDF. | Hongyu Sun Siyu He Li Wu Zeying Cao Xian Sun Mingwei Xu Shan Lu Mingdi Xu Baoming Ning Huimin Sun Tiqiao Xiao Peter York Xu Xu Xianzhen Yin Jiwen Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 1 |
| 14 | 显示文摘 | Xu Baoming Cheng Qian Luo Yan | 2011 | Chinese J Struct Chem2011，30，11： | 1 |
| 15 | Role of oxygen-containing groups on MWCNTs in enhanced separation and permeability performance for PVDF hybrid ultrafiltration membranes显示文摘 | Jilan Ma Yufen Zhao Zhiwei Xu Chunying Min Baoming Zhou Yinglin Li Baodong Li Jiarong Niu | 2013 | Desalination2013，，： | 1 |
| 16 | Design of Nonlinary Rate-compatible LDPC Codes Utilizing Bit-wise Shortening Method 显示文摘 | Zhou Lin Bai Baoming Xu Ming | 2010 | IEEE Communication Letters2010，14，10： | 1 |
| 17 | Design of Nonlinary Rate-compatible LDPC Codes Utilizing Bit-wise Shortening Method 显示文摘 | Zhou Lin Bai Baoming Xu Ming | 2010 | IEEE Communication Letters2010，14，10： | 1 |
| 18 | (E)-β-Farnesene synthase genes affect aphid (Myzus persicae) infestation in tobacco (Nicotiana tabacum)显示文摘 | Xiudao Yu Huw Jones Youzhi Ma Genping Wang Zhaoshi Xu Baoming Zhang Yongjun Zhang Guangwei Ren John Pickett Lanqin Xia | 2012 | Functional & Integrative Genomics2012，，1： | 1 |
| 19 | Sarcomatoid Hepatocellular Carcinoma Diagnosed by FDG PET/CT显示文摘 | Baoming Mi Weixing Wan Chunjing Yu Xuyang You Qiaoling Xu | 2011 | Clinical Nuclear Medicine2011，，10： | 1 |
| 20 | Construction of Short-Block Nonbinary LDPC Codes Based on Cyclic Codes显示文摘In this paper, we focus on shortblock nonbinary LDPC(NB-LDPC) codes based on cyclic codes. Based on Tanner graphs' isomorphism, we present an efficient search algorithm for finding non-isomorphic binary cyclic LDPC codes. Notice that the parity-check matrix H of the resulting code is square and not of full rank, and its row weight and column weight are the same. By replacing the ones in the same column of H with a nonzero element of fi nite fi elds GF(q), a class of NB-LDPC codes over GF(q) is obtained. Numerical results show that the constructed codes perform well over the AWGN channel and have fast decoding convergence. Therefore, the proposed NB-LDPC codes provide a promising coding scheme for low-latency and high-reliability communications. | Hengzhou Xu Baoming Bai Min Zhu Bo Zhang Yulong Zhang | 2017 | China Communications2017，14，8： | 1 |
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