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| 1 | Graphene and cobalt phosphide nanowire composite as an anode material for high performance lithium-ion batteries显示文摘合成一经由一个灵巧的热水的方法的磷化物 nanowires 和减少的 graphene 氧化物(表示 CoP/RGO ) 与随后的退火步相结合的钴合成被报导。结果合成介绍大特定的表面区域和提高的电导率,它能有效地便于充电运输并且在 lithiation/de-lithiation 过程期间在体积提供变化。作为结果, CoP/RGO nanocomposite 表明 960 | Jun Yang Yu Zhang Chencheng Sun Hongzheng Liu Laiquan Li Weili Si Wei Huang Qingyu Yan Xiaochen Dong | 2016 | Nano Research2016，9，3： | 8 |
| 2 | A new lignan and active compounds inhibiting NF-κB signaling pathway from Caulis Trachelospermi显示文摘A new dibenzylbutyrolactone lignan named matairesinol 4'-O-β-D-cellobioside(1),together with a known compound(7R,85)-dihydrodehydrodiconiferyl alcohol(2)was isolated from Caulis Trachelospermi.The extract of Caulis Trachelospermi,which was separated by 80% alcohol extraction and subsequent HP-20 macroporous resin column chromatography,and its main components trachelogenin(3),nortrachelogenin(4),matairesinol(5)showed moderate inhibiting activities on NF-κB signaling pathway induced by TNFα,with the IC_(50) values of 17.7μg/mL,17.9μM,49.4μM and 29.1μM,respectively. | Chencheng Zhu LingJing Nengjiang Yu Xuedong Yang Yimin Zhao | 2013 | Acta Pharmaceutica Sinica B2013，3，2： | 6 |
| 3 | Functional Connectivity-Based Modelling Simulates SubjectSpecific Network Spreading Effects of Focal Brain Stimulation显示文摘Neurostimulation remarkably alleviates the symptoms in a variety of brain disorders by modulating the brain-wide network. However, how brain-wide effects on the direct and indirect pathways evoked by focal neurostimulation elicit therapeutic effects in an individual patient is unknown. Understanding this remains crucial for advancing neural circuit-based guidance to optimize candidate patient screening, pre-surgical target selection, and post-surgical parameter tuning. To address this issue, we propose a functional brain connectome-based modeling approach that simulates the spreading effects of stimulating different brain regions and quantifies the rectification of abnormal network topology in silico. We validated these analyses by pinpointing nuclei in the basal ganglia circuits as top-ranked targets for 43 local patients with Parkinson's disease and 90 patients from a public database. Individual connectome-based analysis demonstrated that the globus pallidus was the best choice for 21.1% and the subthalamic nucleus for 19.5% of patients. Down-regulation of functional connectivity(up to 12%) at these prioritized targets optimally maximized the therapeutic effects. Notably, the priority rank of the subthalamic nucleus significantly correlated with motor symptom severity(Unified Parkinson's Disease Rating Scale III) in the local cohort. These findings underscore the potential of neural network modeling for advancing personalized brain stimulation therapy,and warrant future experimental investigation to validate its clinical utility. | Xiaoyu Chen Chencheng Zhang Yuxin Li Pei Huang Qian Lv Wenwen Yu Shengdi Chen Bomin Sun Zheng Wang | 2018 | Neuroscience Bulletin2018，34，6： | 2 |
| 4 | Study on surface wave-induced mixing of transport flux residue under typhoon conditions显示文摘The transport flux residue of surface waves plays an important role in a variety of ocean phenomena,for example,the change in sea surface temperature(SST)and upper mixed layer profile that were studied in a series of recent papers.In the previous studies,its effect was discussed rigorously and fragmented based on numerical modeling.Here we propose a relatively comprehensive and simplified exposition of the wave transport flux residue,and focus on its influence under typhoon conditions with strong background current.An analogue Reynolds Number is presented for tentative comparison with wave-generated turbulence mixing,especially in the coastal area.Numerical results indicate that both overwhelming dynamical mixing processes can remarkably change the coastal environment,and should not be ignored consciously for further marine hazards assessment. | YANG Yongzeng SHI Yongfang YU Chencheng TENG Yong SUN Meng | 2019 | Journal of Oceanology and Limnology2019，37，6： | 1 |
| 5 | Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression显示文摘Sonic hedgehog (Shh) signaling is essential for the proliferation of cerebellar granule neuron progenitors (CGNPs), and its misregulation is linked to various disorders, including cerebellar cancer medulloblastoma (MB). During vertebrate neural development, RNF220, a ubiquitin E3 ligase, is involved in spinal cord patterning by modulating the subcellular location of glioma-associated oncogene homologs (Glis) through ubiquitination. RNF220 is also required for full activation of Shh signaling during cerebellum development in an epigenetic manner through targeting embryonic ectoderm development. ZC4H2 was reported to be involved in spinal cord patterning by acting as an RNF220 stabilizer. Here, we provided evidence to show that ZC4H2 is also required for full activation of Shh signaling in CGNP and MB progression by stabilizing RNF220. In addition, we found that the ubiquitin E3 ligase RING finger LIM domain-binding protein (RLIM) is responsible for ZC4H2 stabilization via direct ubiquitination, through which RNF220 is also thus stabilized. RLIM is a direct target of Shh signaling and is also required for full activation of Shh signaling in CGNP and MB cell proliferation. We further provided clinical evidence to show that the RLIM‒ZC4H2‒RNF220 cascade is involved in Shh-group MB progression. Disease-causative human RLIM and ZC4H2 mutations affect their interaction and regulation. Therefore, our study sheds light on the regulation of Shh signaling during cerebellar development and MB progression and provides insights into neural disorders caused by RLIM or ZC4H2 mutations. | Yuwei Li Chencheng Yang Huishan Wang Ling Zhao Qinghua Kong Yu Cang Shuhua Zhao Longbao Lv Yan Li Bingyu Mao Pengcheng Ma | 2022 | Journal of Molecular Cell Biology2022，14，1： | 0 |
| 6 | Disturbance rejection for biped robots during walking and running using control moment gyroscopes显示文摘Keeping balance in movement is an important premise for biped robots to complete various tasks.Now,the balance control of biped robots mainly depends on the cooperation of various joints of the robot's body.When robots move faster,the adjustment allowance of joints is reduced,and the robot's anti-disturbance ability will inevitably decline.To solve this problem,the control moment gyroscope(CMG)is creatively used as an auxiliary stabilisation device for fully actuated biped robots and the CMG assistance strategy,which can be integrated into the biped's balance control framework,is proposed.This strategy includes model predictive control module,distribution module,and CMG precession controller.Under the command of it,CMGs can effectively assist the robot in resisting impact and returning to initial positions in time.The results of anti-impact simulation on the walking and running biped robot prove that,with the help of CMGs,the robot's ability to resist disturbance and remain stable is significantly improved.The cover image is based on the Original Article Disturbance rejection for biped robots during walking and running using control moment gyroscopes by Haochen Xu et al.,http://gffzzd3cc09b8251d45dfs9wof0ok5696v6pf5.ffgz.tsg.suse.edu.cn/10.1049/csy2.12070. | Haochen Xu Zhangguo Yu Xuechao Chen Chencheng Dong Huanzhong Chen Qiang Huang | 2022 | IET Cyber-Systems and Robotics2022，4，4： | 0 |
| 7 | Exploring the association between gastrointestinal heat retention syndrome and adult chronic eczema: A caseecontrol study显示文摘Objective:To investigate the association between gastrointestinal heat retention syndrome(GHRS)and adult chronic eczema.Methods:This caseecontrol study compared GHRS/GHRS accompanied by damp-heat syndrome(GHRSDHS)and other patient characteristics between subjects with(cases)and without chronic eczema(controls)to identify potential factors associated with this condition.Semi-structured questionnaires were used to collect data via face-to-face interviews.Participants were recruited from Dongzhimen Hospital affiliated with Beijing University of Chinese Medicine.A logistic regression analysis was performed on the collected data,and odds ratios(ORs)were calculated.Results:A total of 168 cases and 172 controls were recruited.Among the cases of adult chronic eczema,there were 79 subjects with GHRS and 68 with GHRS-DHS.Sex(P=.02,OR=0.54,95%confidence interval[CI]:0.32-0.91),GHRS(P=.04,OR=1.90,95%CI:1.02-3.51),GHRS-DHS(P<.001,OR=4.89,95%CI:2.36-10.15),high sweet food consumption(P=.04,OR=2.03,95%CI:1.03-3.97),and mental stress(P=.01,OR=2.37,95%CI:1.26-4.47)were each found to be associated with chronic eczema.Furthermore,GHRS had a weak positive correlation with eczema EASI severity as measured by the eczema area and severity index(EASI)(P=003).Conclusion:GHRS/GHRS-DHS may be associated with adult chronic eczema.In the future,prospective cohort studies with larger samples should be conducted to investigate the cause and effect association between GHRS and adult chronic eczema. | Chencheng Mei He Yu Wenlong Li Xueyan Ma Yunbi Zhang Qi Sun Yuhong Kong Tiegang Liu Teck Chuan Kong Xiaohong Gu | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，2： | 0 |
| 8 | Task-space Whole-body Control with Variable Contact Force Control for Position-controlled Humanoid Adaptation to Unknown Disturbance显示文摘Whole-body control is beneficial for improving the disturbance adaptation of humanoid robots,since it can simultaneously optimize desired joint torque,joint acceleration,and contact force while considering whole-body dynamics and other physical limits.However,the lack of torque feedback information prevents the position-controlled humanoids from utilizing whole-body control directly,because it enhances the difficulty of guaranteeing desired contact force which is important for maintaining stability.In this paper,a whole-body control that integrates task-space inverse dynamics and variable contact force control is proposed for position-controlled humanoids to enhance the robot’s adaptability toward the unknown disturbance.The task-space inverse dynamics generates the desired joint acceleration and contact force with the consideration of whole-body dynamics and other limits to track the references.The variable contact force control modifies references related to Center of Mass(CoM)and end effectors to ensure reasonable contact force tracking performance,thereby assuring good tracking performance of CoM and momentum to maintain robot stability.Simulations and experiments of balancing and walking under unknown disturbance have been successfully conducted on a position-controlled humanoid robot,BHR-7P3,with the proposed method. | Zelin Huang Chencheng Dong Zhangguo Yu Xuechao Chen Fei Meng Qiang Huang | 2023 | Journal of Bionic Engineering2023，20，5： | 0 |
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