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| 1 | BZR1 Family Transcription Factors Function Redundantly and Indispensably in BR Signaling but Exhibit BRI1-Independent Function in Regulating Anther Development in Arabidopsis显示文摘BRASSINAZOLE-RESISTANT 1 family proteins(BZRs)are central transcription factors that govern brassinosteroid(BR)-regulated gene expression and plant growth.However,it is unclear whether there exists a BZR-independent pathway that mediates BR signaling.In this study,we found that disruption of all BZRs in Arabidopsis generated a hextuple mutant(bzr-h)displaying vegetative growth phenotypes that were almost identical to those of the null mutant of three BR receptors,bri1brl1brl3(bri-t).By RNA sequencing,we found that global gene expression in bzr-h was unaffected by 2 h of BR treatment.The anthers of bzr-h plants were loculeless,but a similar phenotype was not observed in bri-t,suggesting that BZRs have a BR signaling-independent regulatory role in anther development.By real-time PCR and in situ hybridization,we found that the expression of SPOROCYTELESS(SPL),which encodes a transcription factor essential for anther locule development,was barely detectable in bzr-h,suggesting that BZRs regulate locule development by affecting SPL expression.Our findings reveal that BZRs are indispensable transcription factors required for both BR signaling and anther locule development,providing new insight into the molecular mechanisms underlying the microsporogenesis in Arabidopsis. | Lian-Ge Chen Zhihua Gao Zhiying Zhao Xinye Liu Yongpeng Li Yuxiang Zhang Xigang Liu Yu Sun Wenqiang Tang | 2019 | Molecular Plant2019，12，10： | 11 |
| 2 | Long-term effects of early antibiotic intervention on blood parameters,apparent nutrient digestibility, and fecal microbial fermentation profile in pigs with different dietary protein levels显示文摘Backgroud: This study aimed to determine the effects of early antibiotic intervention(EAI) on subsequent blood parameters, apparent nutrient digestibility, and fecal fermentation profile in pigs with different dietary crude protein(CP) levels. Eighteen litters of piglets(total 212) were randomly allocated to 2 groups and were fed a creep feed diet with or without in-feed antibiotics(olaquindox, oxytetracycline calcium and kitasamycin) from postnatal d 7 to d 42. On d 42, the piglets within the control or antibiotic group were mixed, respectively, and then further randomly assigned to a normal-(20%, 18%, and 14% CP from d 42 to d 77, d 77 to d 120, and d 120 to d 185,respectively) or a low-CP diet(16%, 14%, and 10% CP from d 42 to d 77, d 77 to d 120, and d 120 to d 185,respectively), generating 4 groups. On d 77(short-term) and d 185(long-term), serum and fecal samples were obtained for blood parameters, microbial composition and microbial metabolism analysis.Results: EAI increased(P < 0.05) albumin and glucose concentrations in low-CP diet on d 77, and increased(P < 0.05) urea concentration in normal-CP diet. On d 185, EAI increased(P < 0.05) globulin concentration in normal-CP diets, but decreased glucose concentration. For nutrient digestibility, EAI increased(P < 0.05)digestibility of CP on d 77. For fecal microbiota, the EAI as well as low-CP diet decreased(P < 0.05) E. coli count on d 77. For fecal metabolites, on d 77, EAI decreased(P < 0.05) total amines concentration but increased skatole concentration in low-CP diet. On d 185, the EAI increased(P < 0.05) putrescine and total amines concentrations in low-CP diets but reduced(P < 0.05) in the normal-CP diets. The low-CP diet decreased the concentrations of these compounds.Conclusions: Collectively, these results indicate that EAI has short-term effects on the blood parameters and fecal microbial fermentation profile. The effects of EAI varied between CP levels, which was characterized by the significant alteration of glucose and putrescine concentration. | Miao Yu Chuanjian Zhang Yuxiang Yang Chunlong Mu Yong Su Kaifan Yu Weiyun Zhu | 2018 | Journal of Animal Science and Biotechnology2018，9，1： | 6 |
| 3 | Protective effect of oxysophoridine on cerebral ischemia/reperfusion injury in mice显示文摘Oxysophoridine, a new alkaloid extracted from Sophora alopecuroides L., has been shown to have a protective effect against ischemic brain damage. In this study, a focal cerebral ischemia/reperfusion injury model was established using middle cerebral artery occlusion in mice. Both 62.5, 125, and 250 mg/kg oxysophoridine, via intraperitoneal injection, and 6 mg/kg nimodipine, via intragastric administration, were administered daily for 7 days before modeling. After 24 hours of reperfusion, mice were tested for neurological deficit, cerebral infarct size was assessed and brain tissue was collected. Results showed that oxysophoridine at 125, 250 mg/kg and 6 mg/kg nimodipine could reduce neurological deficit scores, cerebral infarct size and brain water content in mice. These results provided evidence that oxysophoridine plays a protective role in cerebral ischemia/reperfusion injury. In addition, oxysophoridine at 62.5, 125, and 250 mg/kg and 6 mg/kg nimodipine increased adenosine-triphosphate content, and decreased malondialdehyde and nitric oxide content. These compounds enhanced the activities of glutathione-peroxidase, superoxide dismutase, catalase, and lactate dehydrogenase, and decreased the activity of nitric oxide synthase. Protein and mRNA expression levels of N-methyl-D-aspartate receptor subunit NR1 were markedly inhibited in the presence of 250 mg/kg oxysophoridine and 6 mg/kg nimodipine. Our experimental findings indicated that oxysophoridine has a neuroprotective effect against cerebral ischemia/reperfusion injury in mice, and that the effect may be due to its ability to inhibit oxidative stress and expression of the N-methyl-D-aspartate receptor subunit NR1. | Hongbo Wang Yuxiang Li Ning Jiang Xiaoping Chen Yi Zhang Kuai Zhang Tengfei Wang Yinju Hao Lin Ma Chengjun Zhao Yanrong Wang Tao Sun Jianqiang Yu | 2013 | Neural Regeneration Research2013，8，15： | 5 |
| 4 | A Predictive 6G Network with Environment Sensing Enhancement:From Radio Wave Propagation Perspective显示文摘In order to support the future digital society,sixth generation(6G)network faces the challenge to work efficiently and flexibly in a wider range of scenarios.The traditional way of system design is to sequentially get the electromagnetic wave propagation model of typical scenarios firstly and then do the network design by simulation offline,which obviously leads to a 6G network lacking of adaptation to dynamic environments.Recently,with the aid of sensing enhancement,more environment information can be obtained.Based on this,from radio wave propagation perspective,we propose a predictive 6G network with environment sensing enhancement,the electromagnetic wave propagation characteristics prediction enabled network(EWave Net),to further release the potential of 6G.To this end,a prediction plane is created to sense,predict and utilize the physical environment information in EWave Net to realize the electromagnetic wave propagation characteristics prediction timely.A two-level closed feedback workflow is also designed to enhance the sensing and prediction ability for EWave Net.Several promising application cases of EWave Net are analyzed and the open issues to achieve this goal are addressed finally. | Gaofeng Nie Jianhua Zhang Yuxiang Zhang Li Yu Zhen Zhang Yutong Sun Lei Tian Qixing Wang Liang Xia | 2022 | China Communications2022，19，6： | 4 |
| 5 | Effect of particle motion on the hydraulic collection of coarse spherical particles显示文摘Deep-sea mining,through which shattered coarse solid mineral resources are hydraulically collected and transported,is a promising solution for problems associated with resource exhaustion.This study reports some interesting phenomena observed in a series of upward pumping experiments conducted on a coarse sphere with a 2-cm radius.The sphere was hydraulically lifted using a vertical pipe with a 5-cm radius suspended above the sphere.Remarkably,the tangential motion benefited the collection.The discrete element method-computational fluid dynamics was used to investigate the collection mechanism;this method was used to simulate the collecting processes of the sphere under different initial motion conditions.The simulated results agreed well with the experimental observations.The vortices over the sphere induced by its motion coupled with the main stream mainly provide sufficient lift force to raise the sphere. | Yuxiang Chen Hong Xiong Hui Cheng Chunliang Yu Jiahua Xie | 2020 | Acta Mechanica Sinica2020，36，1： | 4 |
| 6 | From titanates to TiO_2 nanostructures: Controllable synthesis, growth mechanism, and applications显示文摘The design and fabrication of nanostructures based on titanium dioxide (TiO 2 ) have attracted much attention because of their low cost, non-toxicity, stability, and potential applications in industry and technology. Recently, one-dimensional (1D) structured titanates have been used as titanium source to prepare TiO 2 nanostructures with various crystalline phases, shapes, sizes, exposed facets, and hierarchical structures. Among the synthetic strategies, hydrothermal method is a facile route to controllable preparation of well-crystalline TiO 2 in one step. Herein, we review our recent progress in transferring 1D titanates into TiO 2 nanostructures through hydrothermal method, including the transformation mechanism and applications. | XU DongSheng LI JianMing YU YuXiang LI JingJian | 2012 | Science China Chemistry2012，55，11： | 3 |
| 7 | High-performance all-polymer solar cells enabled by a novel low bandgap non-fully conjugated polymer acceptor显示文摘The non-fully conjugated polymer as a new class of acceptor materials has shown some advantages over its small molecular counterpart when used in photoactive layers for all-polymer solar cells(all-PSCs),despite a low power conversion efficiency(PCE)caused by its narrow absorption spectra.Herein,a novel non-fully conjugated polymer acceptor PFY-2TS with a low bandgap of~1.40 eV was developed,via polymerizing a largeπ-fused small molecule acceptor(SMA)building block(namely YBO)with a non-conjugated thioalkyl linkage.Compared with its precursor YBO,PFY-2TS retains a similar low bandgap but a higher LUMO level.Moreover,compared with the structural analog of YBO-based fully conjugated polymer acceptor PFY-DTC,PFY-2TS shows a similar absorption spectrum and electron mobility,but significantly different molecular crystallinity and aggregation properties,which results in optimal blend morphology with a polymer donor PBDB-T and physical processes of the device in all-PSCs.As a result,PFY-2TS-based all-PSCs achieved a PCE of 12.31%with a small energy loss of 0.56 eV enabled by the reduced non-radiative energy loss(0.24 eV),which is better than that of 11.08%for the PFY-DTC-based ones.Our work clearly demonstrated that non-fully conjugated polymers as a new class of acceptor materials are very promising for the development of high-performance all-PSCs. | Qunping Fan Ruijie Ma Tao Liu Jianwei Yu Yiqun Xiao Wenyan Su Guilong Cai Yuxiang Li Wenhong Peng Tao Guo Zhenghui Luo Huiliang Sun Lintao Hou Weiguo Zhu Xinhui Lu Feng Gao Ellen Moons Donghong Yu He Yan Ergang Wang | 2021 | Science China Chemistry2021，64，8： | 3 |
| 8 | Implementation Framework and Validation of Cluster-Nuclei Based Channel Model Using Environmental Mapping for 6G Communication Systems显示文摘With the research of the upcoming sixth generation(6 G) systems, new technologies will require wider bandwidth, larger scale antenna arrays and more diverse wireless communication scenarios on the future channel modeling. Considering channel model is prerequisite for system design and performance evaluation of 6 G technologies, we face a challenging task: how to accurately and efficiently model 6 G channel for various scenarios? This paper tries to answer it. Firstly, the features of cluster-nuclei(CN) and principle of cluster-nuclei based channel model(CNCM) are introduced. Then, a novel modeling framework is proposed to implement CNCM,which consists four steps: propagation environment reconstruction, cluster-nuclei identification, multipath parameters generation, and channel coefficients generation. Three-dimensional environment with material information is utilized to map CN with scatterers in the propagation pathway. CN are identified by geometrical and electric field calculation based on environmental mapping, and multipath components within CN are calculated by statistical characteristics of angle, power and delay domains. Finally, we present a three-level verification structure to investigate the accuracy and complexity of channel modeling comprehensively. Simulation results reveal that CNCM can perform higher accuracy than geometrybased stochastic model while lower complexity compared with ray-tracing model for practical propagation environment. | Li Yu Yuxiang Zhang Jianhua Zhang Zhiqiang Yuan | 2022 | China Communications2022，19，4： | 3 |
| 9 | Interference pattern generation and simulation in the single beam of a white light continuum显示文摘We demonstrate the interference phenomenon in the White Light Continuum(WLC) generated by a single femtosecond laser beam. Different kinds of spatial interference patterns of the WLC generation under various conditions were investigated. The spatial patterns were attributed to interference between the filaments in the WLC generated by the fundamental laser beam yielding the diffraction effect from spatial confinement. Simulations of different patterns were performed. By comparing the results of simulation with those of experiments,the distances of several micrometers between the neighboring filaments can be derived,which agree with the literature values from direct measurements. | YU ZhiHao & WENG YuXiang Laboratory of Soft Matter Physics,Institute of Physics,Chinese Academy of Sciences,and National Laboratory of Condensed Matter Physics,Beijing 100190,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，6： | 2 |
| 10 | Untangling the contributions of meteorological conditions and human mobility to tropospheric NO_(2) in Chinese mainland during the COVID-19 pandemic in early 2020显示文摘In early 2020,unprecedented lockdowns and travel bans were implemented in Chinese mainland to fight COVID-19;which led to a large reduction in anthropogenic emissions.This provided a unique opportunity to isolate the effects from emission and meteorology on tropospheric nitrogen dioxide(N0_(2)).Comparing the atmospheric N0_(2) in 2020 with that in 2017,we found the changes of emission have led to a 49.3±23.5%reduction,which was〜12%more than satellite-observed reduction of 37.8±16.3%.The discrepancy was mainly a result of changes of meteorology,which have contributed to an 8.1±14.2%increase of N02.We also revealed that the emission-induced reduction of N02 has significantly negative correlations to human mobility,particularly that inside the city.The intra-city migration index derived from Baidu Location-Based-Service can explain 40.4%it 17.7%variance of the emission-induced reduction of N0_(2) in 29 megacities,each of which has a population of over 8 million in Chinese mainland. | Yuxiang Zhang Haixu Bo Zhe Jiang Yu Wang Yunfei Fu Bingwei Cao Xuewen Wang Jiaqi Chen Rui Li | 2021 | National Science Review2021，8，11： | 2 |
| 11 | The effects of portable cooling systems on thermal comfort and work performance in a hot environment显示文摘There are some special spaces in which there is no air conditioning or the people are in move,thus exposing people to a hot environment.In this study,portable cooling systems were proposed and their effects on thermal comfort and work performance were investigated at an air temperature of 32°C.Four conditions were established:cool air towards breathing zone(A),chest and back cooling(B)#combined cooling(C)and no cooling(D).Twenty-eight subjects were exposed to the four conditions in a counterbalanced order.During each exposure they performed tasks and made subjective assessments,while multiple physiological parameters were measured.Compared with no cooling(D),cool air towards breathing zone(A)and chest and back cooling(B)improved work performance by 17.5%and 19.25%,respectively,while decreased the subjects'thermal sensation,skin temperature,and heart rate.When the two cooling systems were combined(C),larger improvements in thermal comfort and work performance were achieved than no cooling(D);the mean thermal sensation rating decreased from 2.4 to 0.7;work performance increased by up to 33%,and physiological parameters including skin temperature,pulse,heart rate and salivary alpha-amylase significantly decreased.The present results suggest that the proposed portable cooling systems could maintain thermal comfort and work performance in a hot environment,while potentially improve air quality for some special spaces. | Jieyu Tang Yu Liu Hui Du Li Lan Yuxiang Sun Jialin Wu | 2021 | Building Simulation2021，14，6： | 2 |
| 12 | Facile Synthesis of FePS3 Nanosheets@MXene Composite as a High-Performance Anode Material for Sodium Storage显示文摘Searching for advanced anode materials with excellent electrochemical properties in sodium-ion battery is essential and imperative for next-generation energy storage system to solve the energy shortage problem.In this work,two-dimensional(2D)ultrathin FePS3 nanosheets,a typical ternary metal phosphosulfide,are first prepared by ultrasonic exfoliation.The novel 2D/2D heterojunction of FePS3 nanosheets@MXene composite is then successfully synthesized by in situ mixing ultrathin MXene nanosheets with FePS3 nanosheets.The resultant FePS3 nanosheets@MXene hybrids can increase the electronic conductivity and specific surface area,assuring excellent surface and interfacial charge transfer abilities.Furthermore,the unique heterojunction endows FePS3 nanosheets@MXene composite to promote the diffusion of Na^+ and alleviate the drastic change in volume in the cyclic process,enhancing the sodium storage capability.Consequently,the few-layered FePS3 nanosheets uniformly coated by ultrathin MXene provide an exceptional reversible capacity of 676.1 mAh g^−1 at the current of 100 mA g^−1 after 90 cycles,which is equivalent to around 90.6% of the second-cycle capacity(746.4 mAh g^−1).This work provides an original protocol for constructing 2D/2D material and demonstrates the FePS3@MXene composite as a potential anode material with excellent property for sodium-ion batteries. | Yonghao Ding Yu Chen Na Xu Xintong Lian Linlin Li Yuxiang Hu Shengjie Peng | 2020 | Nano-Micro Letters2020，12，4： | 2 |
| 13 | Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy——lysosomal pathway显示文摘Nonalcoholic fatty liver disease(NAFLD) is characterized by hepatic steatosis and insulin resistance and there are currently no approved drugs for its treatment.Hyperactivation of mTOR complex1(mTORCl) and subsequent impairment of the transcription factor EB(TFEB)-mediated autophagy-lysosomal pathway(ALP) are implicated in the development of NAFLD.Accordingly,agents that augment hepatic TFEB transcriptional activity may have therapeutic potential against NAFLD.The objective of this study was to investigate the effects of nuciferine,a major active component from lotus leaf,on NAFLD and its underlying mechanism of action.Here we show that nuciferine activated ALP and alleviated steatosis,insulin resistance in the livers of NAFLD mice and palmitic acid-challenged hepatocytes in a TFEB-dependent manner.Mechanistic investigation revealed that nuciferine interacts with the Ragulator subunit hepatitis B X-interacting protein and impairs the interaction of the Ragulator complex with Rag GTPases,thereby suppressing lysosomal localization and activity of mTORC1,which activates TFEB-mediated ALP and further ameliorates hepatic steatosis and insulin resistance.Our present results indicate that nuciferine may be a potential agent for treating NAFLD and that regulation of the mTORCl-TFEB-ALP axis could represent a novel pharmacological strategy to combat NAFLD. | Xiliang Du Chiara Di Malta Zhiyuan Fang Taiyu Shen Xiaodi Niu Meng Chen Bo Jin Hao Yu Lin Lei Wenwen Gao Yuxiang Song Zhe Wang Chuang Xu Zhijun Cao Guowen Liu Xinwei Li | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 2 |
| 14 | Subway Embedded Track Geometric Irregularity Safety Limits显示文摘A coupling dynamic model of a subway train and an embedded track is established to study the safety limits of track irregularities.The simulated vehicle system was a 74-degrees of freedom multi-rigid body model,and the rail was a Timoshenko beam.The slab was a three-dimensional solid finite element model.The sensitive wavelength irregularity was first studied,and then the safety limit of the sensitive wavelength was analyzed.The wheel-rail lateral force exhibited a substantial effect on the track alignment and gauge irregularity safety limit.The wheel-rail vertical force and the rate of wheel load reduction significantly affected the height and cross-level irregularity safety limit.The results demonstrate that the safety limits of the alignment,gauge,height,and cross-level embedded track geometric irregularity are 5.3 mm,[−10.5,8]mm,5.6 mm,and 6 mm,respectively. | Yuxiang Zhang Jian Han Huilai Song Yu Liu | 2021 | Chinese Journal of Mechanical Engineering2021，34，5： | 2 |
| 15 | A Review of the Design and Architecture of Starch-Based Dietary Foods显示文摘Carbohydrates,which are mostly present in sugar,starch,and fiber,are one of the main ingredients of food and the primary source of energy in the human diet.Among these three main sources,starch stands out as one of the most abundant reserves of carbohydrates.Investigating starch would not only enhance our understanding of the functionality of starch in the human body but also aid in the design of novel starch-based dietary foods.The present review first provides a state-of-the-art understanding of the various classifications of dietary starches,including rapidly digesting starch(RDS),slowly digesting starch(SDS),and resistant starch(RS).Moreover,both the in vivo and in vitro determination methods of the digestibility of starch-based dietary foods are discussed.Based on the current understanding,present research strategies to design novel starch-based dietary foods through either the direct addition of modified starch or the alteration of processing conditions are highlighted.Furthermore,certain perspectives related to the future research directions of starch-based foods are also included. | Yuxiang Bai Xiaoxiao Li Hangyan Ji Yu Wang Danni Zheng Yanli Wang Zhengyu Jin | 2021 | Engineering2021，7，5： | 2 |
| 16 | Environment Information-Based Channel Prediction Method Assisted by Graph Neural Network显示文摘Recently,whether the channel prediction can be achieved in diverse communication scenarios by directly utilizing the environment information gained lots of attention due to the environment impacting the propagation characteristics of the wireless channel.This paper presents an environment information-based channel prediction(EICP)method for connecting the environment with the channel assisted by the graph neural networks(GNN).Firstly,the effective scatterers(ESs)producing paths and the primary scatterers(PSs)generating single propagation paths are detected by building the scatterercentered communication environment graphs(SCCEGs),which can simultaneously preserve the structure information and highlight the pending scatterer.The GNN-based classification model is implemented to distinguish ESs and PSs from other scatterers.Secondly,large-scale parameters(LSP)and small-scale parameters(SSP)are predicted by employing the GNNs with multi-target architecture and the graphs of detected ESs and PSs.Simulation results show that the average normalized mean squared error(NMSE)of LSP and SSP predictions are 0.12 and 0.008,which outperforms the methods of linear data learning. | Yutong Sun Jianhua Zhang Yuxiang Zhang Li Yu Qixing Wang Guangyi Liu | 2022 | China Communications2022，19，11： | 1 |
| 17 | Bamboo-inspired cell-scale assembly for energy device applications显示文摘Rapid advances in flexible and wearable smart textiles demand low-cost,high-energy/power-density fiber-shaped supercapacitors(FSCs).The performance of FSCs is determined by the fabrication and assembly of fiber-shaped electrodes(FSEs),where an active charge-storage material is always clad around flexible charge transmission current collectors.Inspired by the tissue structure of natural bamboo,wherein parenchyma cells(PCs)that store nutrients are clad around bamboo fibers(BFs),we propose a strategy for converting bamboo cells into FSEs using conductive BFs and activated PCs as current collectors and active materials,respectively.The assembled electrode has a high specific capacitance of 1454 mF cm^(−2) at 0.64 mA cm^(−2).A solid-state FSC with a pair of bamboo-structured electrodes exhibited a substantially high energy density.Its mechanical flexibility enabled the knitting of wearable wristbands to drive ultra-small voltmeter indicators.This lightweight,low cost,and high-energy-density bamboostructured FSC could enable numerous smart textile applications. | Qiuqin Lin Runan Gao Daohao Li Yun Lu Shiqin Liu Yanglun Yu Yuxiang Huang Wenji Yu | 2022 | npj Flexible Electronics2022，6，1： | 1 |
| 18 | Design anti Preliminary Evaluation of a Pnrtable Device tor the Measurement of Binimpedanee Spectrnseopy显示文摘 | Yang Yuxiang Wang Jue Yu Gang | 2006 | Physiological Measurement2006，，27： | 1 |
| 19 | An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk,local immunosuppression and tumor progression显示文摘Dissecting and understanding the cancer ecosystem,especially that around the tumor margins,which have strong implications for tumor cell infiltration and invasion,are essential for exploring the mechanisms of tumor metastasis and developing effective new treatments.Using a novel tumor border scanning and digitization model enabled by nanoscale resolution-SpaTial Enhanced REsolution Omics-sequencing(Stereo-seq),we identified a 500µm-wide zone centered around the tumor border in patients with liver cancer,referred to as“the invasive zone”.We detected strong immunosuppression,metabolic reprogramming,and severely damaged hepatocytes in this zone.We also identified a subpopulation of damaged hepatocytes with increased expression of serum amyloid A1 and A2(referred to collectively as SAAs)located close to the border on the paratumor side.Overexpression of CXCL6 in adjacent malignant cells could induce activation of the JAK-STAT3 pathway in nearby hepatocytes,which subsequently caused SAAs’overexpression in these hepatocytes.Furthermore,overexpression and secretion of SAAs by hepatocytes in the invasive zone could lead to the recruitment of macrophages and M2 polarization,further promoting local immunosuppression,potentially resulting in tumor progression.Clinical association analysis in additional five independent cohorts of patients with primary and secondary liver cancer(n=423)showed that patients with overexpression of SAAs in the invasive zone had a worse prognosis.Further in vivo experiments using mouse liver tumor models in situ confirmed that the knockdown of genes encoding SAAs in hepatocytes decreased macrophage accumulation around the tumor border and delayed tumor growth.The identification and characterization of a novel invasive zone in human cancer patients not only add an important layer of understanding regarding the mechanisms of tumor invasion and metastasis,but may also pave the way for developing novel therapeutic strategies for advanced liver cancer and other solid tumors. | Liang Wu Jiayan Yan Yinqi Bai Feiyu Chen Xuanxuan Zou Jiangshan Xu Ao Huang Liangzhen Hou Yu Zhong Zehua Jing Qichao Yu Xiaorui Zhou Zhifeng Jiang Chunqing Wang Mengnan Cheng Yuan Ji Yingyong Hou Rongkui Luo Qinqin Li Liang Wu Jianwen Cheng Pengxiang Wang Dezhen Guo Waidong Huang Junjie Lei Shang Liu Yizhen Yan Yiling Chen Sha Liao Yuxiang Li Haixiang Sun Na Yao Xiangyu Zhang Shiyu Zhang Xi Chen Yang Yu Yao Li Fengming Liu Zheng Wang Shaolai Zhou Huanming Yang Shuang Yang Xun Xu Longqi Liu Qiang Gao Zhaoyou Tang Xiangdong Wang Jian Wang Jia Fan Shiping Liu Xinrong Yang Ao Chen Jian Zhou | 2023 | Cell Research2023，33，8： | 1 |
| 20 | Preparation and pho- toelectrochemical properties of functional carbon nanotubes and Ti Co-doped Fe203 thin films 显示文摘 | Liu Ying Wang Dongping Yu Yuxiang | 2012 | Intemational Journal of Hydrogen Energy2012，37，12： | 1 |
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