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| 1 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 2 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 3 | Dissecting and Enhancing the Contributions of High-Molecular-Weight Glutenin Subunits to Dough Functionality and Bread Quality显示文摘Dear Editor, Seed storage proteins (SSPs) are frequently important determinants of crop quality traits (Shewry and Casey,1999).Dissecting and enhancing the genetic contributions of individual SSPs to their target traits are essential for effectively improving crop quality attributes.However,such a task is often difficult to accomplish,because SSPs are frequently expressed from multigene families and exhibit strong allelic variation.Consequently,detailed knowledge of the function of individual SSPs in crop quality trait is still limited.This scenario is well illustrated by high-molecular-weight glutenin subunits (HMWGSs),a complex family of SSPs that are involved in wheat enduse quality through affecting dough functionality (Békés,2012;Rasheed et al.,2014). | Yiwen Li Xuefi An Ran Yang Xiaomin Guo Guidong Yue Renchun Fan Bin Li Zhensheng Li Kunpu Zhang Zhenying Dong Luyan Zhang Jiankang Wang Xu Jia Hong-Qing Ling Aimin Zhang Xiangqi Zhang Daowen Wang | 2015 | Molecular Plant2015，8，2： | 9 |
| 4 | Protective effects of curcumin against human immunodeficiency virus 1 gp120 V3 loop-induced neuronal injury in rats显示文摘Curcumin improves the learning and memory deficits in rats induced by the gp120 V3 loop. The present study cultured rat hippocampal neurons with 1 nM gp120 V3 loop and 1 μM curcumin for 24 hours. The results showed that curcumin inhibited the gp120 V3 loop-induced mitochondrial membrane potential decrease, reduced the mRNA expression of the pro-apoptotic gene caspase-3, and attenuated hippocampal neuronal injury. | Zheng Gong Lijuan Yang Hongmei Tang Rui Pan Sai Xie Luyan Guo Junbin Wang Qinyin Deng Guoyin Xiong Yanyan Xing Jun Dong | 2012 | Neural Regeneration Research2012，7，3： | 5 |
| 5 | Rapid room-temperature synthesis of a porphyrinic MOF for encapsulating metal nanoparticles显示文摘While metal nanoparticles(NPs)have shown great promising applications as heterogeneous catalysts,their agglomeration caused by thermodynamic instability is detrimental to the catalytic performance.To tackle this hurdle,we successfully prepared a functional and stable porphyrinic metal-organic framework(MOF),PCN-224-RT,as a host for encapsulating metal nanoparticles by direct stirring at room temperature.As a result,Pt@PCN-224-RT composites with well-dispersed Pt NPs can be constructed by introducing pre-synthesized Pt NPs into the precursor solution of PCN-224-RT.Of note,the rapid and simple stirring method in this work is more in line with the requirements of environmental friendly and industrialization compared with traditional solvothermal methods. | Huihui He Luyan Li Yang Liu Meruyert Kassymova Dandan Li Liangliang Zhang Hai-Long Jiang | 2021 | Nano Research2021，14，2： | 3 |
| 6 | A general approach to the design of high-performance near-infrared (NIR) D-π-A type fluorescent dyes显示文摘Near infrared(NIR) absorbing and emitting dyes are sought after for their potentials in bioimaging and theranostic applications. They are typically not as stable as dyes absorbing and emitting in the visible spectral range, as the result of a reduced HOMO-LUMO band-gap. Also, they are not as efficient fluorescence emitters due to accelerated internal conversion kinetics. In addition, their large conjugative backbone render them high tendency to form aggregate and low aqueous solubility. In this tutorial, we have described a four-step approach for rational design of organic dyes with an overall high-performance to meet the rigorous requirements of biological applications. Also, some background regarding 'NIR' is provided along with some recent breakthroughs of the field. | Xiao Luo Jin Li Jie Zhao Luyan Gu Xuhong Qian Youjun Yang | 2019 | Chinese Chemical Letters2019，30，4： | 2 |
| 7 | Effects of Cracks on the Mass Transfer of Polymer Electrolyte Membrane Fuel Cell with High Performance Membrane Electrode Assembly显示文摘A two-dimensional geometric model is developed for a polymer electrolyte based on the liquid water penetration mechanism in the membrane electrode assemblies under the action of capillary pressure.The effects of the diameter,number,and distribution of cracks in the micro-pore layers(MPLs)of the modeled MEA on the performance of the PEMFC are simulated to investigate the influence of mass transfer across the membrane.The results indicate that liquid water in the catalyst layer(CL)of the MEA can be discharged to gas channels through the cracks in MEA under the action of capillary pressure,thereby alleviating the flooding in the CL and enhancing the diffusion of oxygen to the CL.When the proportion of the total area of cracks in the active area of the MEA was 8%-12%,crack diameter was 20-30μm,and cracks were distributed uniformly.MEAs with and without cracks were prepared,fuel cells were assembled,and their performance was measured.The effects of cracks on mass transfer were then verified.This study helps prepare MEAs with controllable cracks. | 施金蓉 詹志刚 ZHANG Di YU Yuan YANG Xiaoxiang HE Luyan PAN Mu | 2021 | Journal of Wuhan University of Technology(Materials Science)2021，36，3： | 1 |
| 8 | Determination of three bioactive constituents in moutan cortex by capillary elec- trophoresis with electrochemical detection显示文摘 | Chen Gang Zhang Luyan Yang Pengyuan | 2005 | Analytical Sciences2005，21，： | 1 |
| 9 | Rapid Determination of Paeoniflorin and Three Sugars in Radix Paeoniae Alba by Capillary Electrophoresis显示文摘 | Gang CHEN Luyan ZHANG Pengyuan YANG | 2005 | Analytical Sciences2005，21，3： | 1 |
| 10 | Application of real- time PCR for quantitative detection of Vibrio parahaemolyticus from seafood in eastern China显示文摘 | CAI Tanxi J]ANG Luyan YANG Chengbo | 2006 | FEMS Immunol Meal Microbiol2006，46，2： | 1 |
| 11 | Rapid determination of paeoniflorin and three sugars in radix paeoniae alba by capillary electrophoresis显示文摘 | Gang Chen Luyan Zhang Pengyuan Yang | 2005 | Analytical Sciences2005，21，： | 1 |
| 12 | Determination of four phenolic compounds in Scirpus yagara Ohwi by CE with ampero- metric detection 显示文摘 | Yang Guoxun Zhang Luyan Chen Gang | 2010 | Chromatographia2010，71，2： | 1 |
| 13 | Self-adaptive Algorithm for Simulating Sand Painting in Real-Time显示文摘Sand painting is a form of combination of arts and modern aesthetic, which relies on profound cultural heritage and cultural connotation. To provide the public and artists with an opportunity to better understand sand painting and make art creations surprisingly, this paper proposes a self-adaptive algorithm to simulate sand painting in a real-time way. Our simulation system exploits the height field to simulate sand flow to achieve a fast even real-time target. Seven frequently-used styles of painting techniques are elaborately defined and successfully simulated in our system, including pouring,seeping, dotting, stroking, sweeping, multi-stroking, and pinching. The procedure of sand flow is mainly consist of two key parts: sand accumulation and collapse. The direction field is introduced into the system to control a similar appearance of a normal distribution, which will be of benefit to sand accumulation algorithm. A selfadaptive approach is taken advantage of into sand collapse algorithm to present certain appearances with various details. A color factor is also considered for realistic simulation in this paper in two ways: one is the background color of sand table/canvas and the other is the natural color of sand particles themselves. User feedbacks and experimental results reveal that the algorithm of sand painting simulation in this paper can realize kinds of sand painting arts of creations easily, realistically, effectively and interactively. | YANG Meng JIANG Luyan DING Shu ZHANG Xinyang YAN Shu YANG Gang | 2019 | Chinese Journal of Electronics2019，28，3： | 0 |
| 14 | The mechanodonor-acceptor coupling (MDAC) approach for unidirectional multi-state fluorochromism显示文摘Uni-directional multi-state fluorochromic scaffolds are valuable photofunctional molecules and yet scarce. We report a general approach for their design, i.e., mechanodonor-acceptor coupling(MDAC). A photochromic molecule is a mechanodonor, due to its capability to convert photonic energy into mechanical force. Upon proper coupling, it can be used to drive a mechanochromic molecule for uni-directional multi-state fluorochromism. The embodiment of this approach is a rhodamine-dithienylethylene hydride(RDH), which has been successfully employed in super-resolution localization microscopy. | Luyan Gu Lujia Zhang Xiao Luo Ying Zheng Zhiwei Ye Meng Lv Jinquan Chen Chunlai Chen Yi Xiao Weihong Zhu Xuhong Qian Youjun Yang | 2021 | Science China Chemistry2021，64，2： | 0 |
| 15 | Chemical compositions and biological activities of Flos lonicerae显示文摘Flos lonicerae is the dry flower bud of Lonicera japonica Thunb,and it is a very important Chinese herbal medicine in China.In ancient times,it was widely used to treat the exopathogenic wind-heat,epidemic febrile diseases,sores,carbuncles and some infectious diseases.Modern pharmacological research has indicated that it has anti-inflammatory,anti-bacterial,anti-viral and anti-oxidation activities.This paper reviews the chemical compositions and biological activities of Flos lonicerae in order to provide reference for its application in clinical practice in the future. | Yi’an Shi Luming Pan Luyan Yang Jing Sun Meng Zhang Yu Chen | 2023 | Asian Journal of Traditional Medicines2023，18，2： | 0 |
| 16 | External control of qubit-photon interaction and multi-qubit reset in a dissipative quantum network显示文摘A quantum network is a promising quantum many-body system because of its tailored geometry and controllable interaction. Here,we propose an external control scheme for the qubit-photon interaction and multiqubit reset in a dissipative quantum network,which comprises superconducting circuit chains with microwave drives and filter-filter couplings. The traditional multiqubit reset of the quantum network requires physically disconnected qubits to prevent their entanglement. However, we use an original effect of dissipation, i.e., consuming the entanglement generated by qubits’ interaction, to achieve an external control of the multiqubit reset in an always-connected superconducting circuit. The reset time is independent of the number of qubits in the quantum network. Our proposal can tolerate considerable fluctuations in the system parameters and can be applicable to higherdimensional quantum networks. | Xian-Peng Zhang Li-Tuo Shen Yuan Zhang Luyan Sun Huaizhi Wu Zhen-Biao Yang Zhang-Qi Yin | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，5： | 0 |
| 17 | Cell division factor ZapE regulates Pseudomonas aeruginosa biofilm formation by impacting the pqs quorum sensing system显示文摘Pseudomonas aeruginosa is one of the leading nosocomial pathogens that causes both severe acute and chronic infections.The strong capacity of P.aeruginosa to form biofilms can dramatically increase its antibiotic resistance and lead to treatment failure.The biofilm resident bacterial cells display distinct gene expression profiles and phenotypes compared to their free-living counterparts.Elucidating the genetic determinants of biofilm formation is crucial for the development of antibiofilm drugs.In this study,a highthroughput transposon-insertion site sequencing(Tn-seq)approach was employed to identify novel P.aeruginosa biofilm genetic determinants.When analyzing the novel biofilm regulatory genes,we found that the cell division factor ZapE(PA4438)controls the P.aeruginosa pqs quorum sensing system.The ΔzapE mutant lost fitness against the wild-type PAO1 strain in biofilms and its production of 2-heptyl-3-hydroxy-4(1H)-quinolone(PQS)had been reduced.Further biochemical analysis showed that ZapE interacts with PqsH,which encodes the synthase that converts 2-heptyl-4-quinolone(HHQ)to PQS.In addition,site-directed mutagenesis of the ATPase active site of ZapE(K72A)abolished the positive regulation of ZapE on PQS signaling.As ZapE is highly conserved among the Pseudomonas group,our study suggests that it is a potential drug target for the control of Pseudomonas infections. | Xi Liu Minlu Jia Jing Wang Hang Cheng Zhao Cai Zhaoxiao Yu Yang Liu Luyan ZMa Lianhui Zhang Yingdan Zhang Liang Yang | 2023 | mLife2023，2，1： | 0 |
| 18 | Effect of the withdrawal rate on the microstructure and thermal durability of a third-generation single crystal superalloy显示文摘Single crystal Ni-based superalloys are the typical structural materials for high-pressure turbine blades,and their microstructure is critical in determining their mechanical properties.The withdrawal rate is a key parameter affecting the microstructure during the single crystal growth process.In the present work the effect of the withdrawal rate on the microstructure of a third-generation single crystal superalloy containing 6.8 wt%Re has been investigated,and the creep resistance of the alloy determined.The results showed that increased withdrawal rate refined the dendritic structure,reduced dendritic arm spacing,promoted the growth of secondary tertiary dendrites and decreased solidification segregation with a reduced size ofγ’phase.The porosity density of the ascast alloy first decreased and then increased with the withdrawal rate,while the minimum porosity densityoccurred when the alloy was under the solidification condition of withdrawal rate of 4.5 mm/min.The maximum creep rupture life of 326.4 h of the heat-treated alloys under the test condition of 1100℃/140 MPa also appeared at the alloys under the withdrawal rates of 4.5 mm/min.It is believed that the minimum porosity density and reduced size of theγ’phase may be the main reasons for the enhanced creep rupture life of the alloys with withdrawal rates of 4.5 mm/min.This investigation provides theoretical support and a practical basis for the development of third-generation single crystal superalloys. | Yunsong Zhao Mai Zhang Luyan Yang Yuanyuan Guo Jian Zhang Hui Lu Yanhui Chen Dingzhong Tang | 2021 | Progress in Natural Science:Materials International2021，31，3： | 0 |
| 19 | Effect of abruptly changing withdrawal rate on solidification microstructure in directionally solidified Al-4.5wt%Cu alloy显示文摘Al-4.5wt.%Cu alloy has been directionally solidified at constant and abruptly changing withdrawal rates, respectively. The effects of the withdrawal rate on solidification microstructure, primary dendrite arm spacing(PDAS) and liquid solute distribution in front of the solid-liquid interface were investigated. The experimental results for the PDAS at a constant withdrawal rate agree well with the values calculated by the Hunt, Trivedi and Hunt-Lu models. At an abrupt change in the withdrawal rate, the maximum to minimum ratio of the PDAS at a given solidification parameter, i.e. λ1max/λ1min, is more than 2, and the PDAS values are remarkably history-dependent. Further, the liquid-solute distribution curve based on theoretical calculation shows that the larger the initial withdrawal rate is, the smaller the minimum of liquid solute concentration in front of the solid-liquid interface is after the abrupt change in withdrawal rate. | Yang Luyan Li Shuangming Zhong Hong Ren Ruohua Fu Hengzhi | 2014 | China Foundry2014，11，1： | 0 |
| 20 | Chemical constituents and pharmacological effects of Croton crassifolius显示文摘Croton crassifolius(CC)is a kind of traditional Chinese medicine rich in terpenoids,with among which diterpene species are the most.CC had biological activities in the treatment of cancer,inflammation,ulcerative colitis,osteoporosis and Alzheimer’s disease.This study reviews the chemical compositions and pharmacological activities of CC to provide reference for further research. | Luyan Yang Yibo Wang Xinyao Wang Xiaoxia Xu Yunpeng Yang Meng Zhang Yu Chen | 2024 | Asian Journal of Traditional Medicines2024，19，2： | 0 |
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