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| 1 | Role of Fas/FasL Pathway-mediated Alveolar Macrophages Releasing Inflammatory Cytokines in Human Silicosis显示文摘The role of Fas/Fas ligand (FasL) in mediating alveolar macrophage (AM)-derived inflammatory cytokines in 29 human lung silicosis patients and 6 controls was studied.It showed that the serum levels of IL-1β,TNF-α,IL-8,MIP-1α,MCP-1,and TGF-β1were higher in silicosis patients than in controls,and increased with the progression of silicosis except TGF-β1 and IL-8.TGF-β1,IL-8,MCP-1,MIP-1αwere efficiently down-regulated by anti-FasL antibody or caspase-8 inhibitor,indicating that Fas/FasL signaling promotes the | YAO San Qiao HE Qin Cheng YUAN Ju Xiang CHEN Jie CHEN Gang LU Yao BAI Yu Ping ZHANG Chun Min YUAN Yang XU Ying Jun | 2013 | Biomedical and Environmental Sciences2013，26，11： | 13 |
| 2 | Frequency control ancillary service provided by a wind farm:dual-BESS scheme显示文摘Network frequency control function is incorporated into a grid-connected wind farm-dual battery energy storage system(BESS)scheme.The design of the scheme takes advantage of the rapid response characteristics of the BESS and the in-built short-term overloading capability of the associated power conversion devices.A control strategy to regulate the BESS output power is then proposed.It is shown that the frequency control action offered by the BESS complements amicably with that of conventional generators in enhancing the frequency regulation attribute of the grid system. | Dailin YAO San Shing CHOI King Jet TSENG Tek Tjing LIE | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，2： | 4 |
| 3 | Two new benzophenone glucosides from Cratoxylon cochinchinensis显示文摘二新 benzophenone 配糖物从 Cratoxylum cochinchinense 的弄干的茎的 60% 乙醇摘录被孤立。结构作为 3-O-β 被阐明; -d-glucopyranosyl-2′,4,6′-trihydroxy-benzophenone 和 3-O-β -d-glucopyranosyl-2′,5,6′-trihydroxybenzophenone 根据光谱、化学方法。 | Hai Yang Yu San Lin Jin Xue.Zhang Yuan Liu Yang Fu Ou Nai Li Wang Xin Sheng Yao | 2009 | Chinese Chemical Letters2009，20，4： | 2 |
| 4 | Optimized tool path generation for fast tool servo diamond turning of micro-structured surfaces显示文摘 | De Ping Yu Sze Wei Gan Yoke San Wong Geok Soon Hong Mustafizur Rahman Jin Yao | 2012 | The International Journal of Advanced Manufacturing Technology2012，，9： | 1 |
| 5 | Adsorption equilibria and kinetics for phenol and cresol onto polymeric adsorbents: Effects of adsorbents/adsorbatcs structure and interface 显示文摘 | Liu Fu Qiang Xia Ming Fang Yao San Li | 2008 | Journal of Hazardous Materials2008，152，2： | 1 |
| 6 | State of modal parameter identification显示文摘 | Tan Dongmei Yao San Qu Weilian | 2002 | Journal of Huazhong University of Science and Tchonology2002，19，3： | 1 |
| 7 | Intratypic variants of human papillomavirus type 16 and risk of cervical Neoplasia in Taiwan显示文摘 | Ya‐Ju Chang Hui‐Chi Chen Mei‐Hung Pan Bor‐Heng Lee San‐Lin You Ching‐Yu Lin Yi‐Chun Chou Chang‐Yao Hsieh Yu‐Juen Cheng Kai‐Li Liaw Ann W. Hsing Mark Schiffman Chien‐Jen Chen | 2013 | J. Med. Virol2013，，： | 1 |
| 8 | Synthesis of ethyltert-butylether from tert-butyl alcohol and ethanol on Strong acid cation-exchange resins 显示文摘 | Yang bo lun Yang san ba Yao rui qing | 2000 | Reactive and Functional Polymers2000，44，2： | 1 |
| 9 | A novel CHS/ALG bi-layer composite membrane with sustained antimicrobial efficacy used as wound dressing显示文摘A membrane composed of an alginate(ALG) layer and a chitosan(CHS) layer with sustained antimicrobial efficacy was prepared.Ciprofloxacin HC1(CIP) was incorporated into the ALG layer.Morphological feature of the composite membrane was analyzed by scanning electron microscopy(SEM).Water uptake capacity,in vitro drug release,and in vitro antimicrobial activity were evaluated.The composite membrane exhibited perfect binding characteristic between the two layers.The water uptake capacity of all the membranes was above 800%.The CIP could release from the composite membranes for 48 h.The membrane could control the bacterial growth persistently.The results suggested that this CHS/ALG composite membrane incorporated with CIP had the potential for wound dressing application. | Yang Dong Hong Zhuo Liu Lu Xu Gang Li Zi Ning Ma Fei Han Hui Min Yao Yah Hui Sun San Ming Li | 2010 | Chinese Chemical Letters2010，21，8： | 1 |
| 10 | Mouth lip-reading in se-quence classification 显示文摘 | Wei San Hongxun Yao Wen Gao | 2011 | Journal of Chinese Information2011，16，： | 1 |
| 11 | Design and simulation of betavoltaic battery using large-grain polysilicon显示文摘 | Shulin Yao Zijun Song Xiang Wang Haisheng San Yuxi Yu | 2012 | Applied Radiation and Isotopes2012，，10： | 1 |
| 12 | Wavelength-Selecttable Lasers With Bragg-Wave- length-Detuned Sampled Grating Reflectors 显示文摘 | Yao Chiu- Lin Lee San - Liang Jang Ing - Fa | 2006 | Journal of lightwave technology2006，24，9： | 1 |
| 13 | Expression of Thioredoxin System Protein Induced by Silica in Rat Lung Tissue显示文摘Silicosis,a potentially fatal global occupational disease, is characterized by progressive deterioration of pulmonary function and irreversible fibrosis resulting from crystalline silicon dioxide or silica inhalation.Extensive pieces of evidence[1-3]manifest that inhaled silica particles could directly or indirectly cause excess generation of reactive oxygen species(ROS),which plays a key role in the pathogenesis of silicosis.In order to maintain the cellular redox balance,the main function of thioredoxin(Trx)/thioredoxin reductase(TrxR)systems is to scavenge the ROS. TrxR, as a reductase of Trx currently known only,has the function of antioxidation and scavenging free radicals[4].In addition, recent in vitro studies demonstrate that Trx interacts directly with and inhibits the activity of apoptosis-regulating kinase-1(ASK-1)[5].The damaged cell of lung tissue caused by ROS may be an important link to ASK-1 triggered cell apoptosis.Zhu et al.[1] reported that silica could aggravate oxidative stress and promote the development of silicosis in rat lungs after silica exposure by downregulating the expression of TrxR and poor Trx activity. The specific mechanism of imbalance of reduction/oxidation status in silicosis is poorly understood.Our previous studies[6]demonstrated that oxidative stress in rats induced by silica leads to increased peroxiredoxins(Prxs) protein reactivity to resist oxidative stress, and Trx as an electron donor is functionally associated with Prxs. Hence, we propose a hypothesis that silica exposure may lead to the disturbance of the function of the Trx/TrxR system,contributing to further oxidative damage. | GUAN Yi LI Gai LIU Nan WANG Yong Heng ZHOU Qiang CHANG Mei Yu ZHAO Lin Lin YAO San Qiao | 2022 | Biomedical and Environmental Sciences2022，35，7： | 0 |
| 14 | Long-term Di-(2-ethylhexyl) phthalate Exposure Disturbs the Lipid Metabolism Profiles and Hepatic Enzymes in Male Rats:A UPLC-MS-based Serum Metabolomics Analysis显示文摘In recent years,many investigations have indicated that environmental endocrine disruptors(EEDs)may accelerate the development of obesity[1].One kind of EEDs,di-(2-ethylhexyl)phthalate(DEHP),is ubiquitous in natural environments due to its role in the manufacture and use of plastic products[2]. | DONG Xin Wen WU Wei Dong YAO San Qiao ZHANG Yun Bo WANG Cheng WU Hao Yu NA Xiao Lin | 2021 | Biomedical and Environmental Sciences2021，34，11： | 0 |
| 15 | Early Changes in Serologic Markers in Workers Exposed to Indium Compounds显示文摘Case reports of lung disease among indiumexposed workers in Japan,the USA,and China over the past two decades have raised public concern about the toxicity of indium and indium compounds.Occupational exposure to indium compounds can result in potentially fatal indium lung disease,which is characterized by pulmonary alveolar proteinosis(PAP)and may progress to fibrosis,with or without emphysema[1]. | LIU Nan GUAN Yi XUE Ling LI Bin YAO San Qiao | 2021 | Biomedical and Environmental Sciences2021，34，3： | 0 |
| 16 | Proteomic Analysis Revealed the Involvement of Autophagy in Rat Acute Lung Injuries Caused by Gas Explosion Based on a Data-Independent Acquisition Strategy显示文摘Gas explosion injury is a compound injury caused by a shock wave,high-temperature flame,or toxic gas directly or indirectly acting on the human body,resulting in multiple organ damage.As a hyperaerated tissue,the lung is the primary organ that experiences an early injury.The pathological manifestations of gas-explosion-induced acute lung injury(ALI)include pulmonary tissue edema. | HONG Shan DING Chun Jie ZHOU Qiang SUN Yun Zhe ZHANG Miao LI Ning DONG Xin Wen GUAN Yi ZHANG Lin TIAN Lin Qiang CAO Jia YAO Wu REN Wen Jie YAO San Qiao | 2023 | Biomedical and Environmental Sciences2023，36，2： | 0 |
| 17 | Surface reconstruction establishing Mott-Schottky heterojunction and built-in space-charging effect accelerating oxygen evolution reaction显示文摘Structural reconstruction of nanomaterials offers a fantastic way to regulate the electronic structure of active sites and promote their catalytic activities.However,how to properly facilitate surface reconstruction to overcome large overpotential that stimulate the surface reconstruction has remained elusive.Herein,we adopt a facile approach to activate surface reconstruction on Ni(OH)_(2) by incorporating F anions to achieve electro-derived structural oxidation process and further boost its oxygen evolution reaction(OER)activity.Ex situ Raman and X-ray photoemission spectroscopy studies indicate that F ions incorporation facilitated surface reconstruction and promotes the original Ni(OH)_(2)transformed into a mesoporous and amorphous F-NiOOH layer during the electrochemical process.Density functional theory(DFT)calculation reveals that this self-reconstructed NiOOH induces a space-charge effect on the p-n junction interface,which not only promotes the absorption of intermediates species(^(*)OH,^(*)O,and^(*)OOH)and charge-transfer process during catalysis,but also leads to a strong interaction of the p-n junction interface to stabilize the materials.This work opens up a new possibility to regulate the electronic structure of active sites and promote their catalytic activities. | Yao Kang Shuo Wang Kwan San Hui Shuxing Wu Duc Anh Dinh Xi Fan Feng Bin Fuming Chen Jianxin Geng Weng-Chon(Max)Cheong Kwun Nam Hui | 2022 | Nano Research2022，15，4： | 0 |
| 18 | Sodium 4-phenylbutyrate Attenuates High-fat Diet-induced Impaired Spermatogenesis显示文摘Objective To determine the mitigating effects of sodium 4-phenylbutyrate(4-PBA) on high-fat diet(HFD)-induced spermatogenesis dysfunction. Methods Male rats(n = 30) were randomly divided into three groups: control, HFD, and 4-PBA(HFD +4-PBA). After 13 weeks, rats were euthanized. Testes and epididymis were harvested for further analysis. Sex hormones were detected, and hematoxylin and eosin staining was performed to examine the histological changes in the testes. Semen samples were collected to evaluate sperm quality. Spermatogenic cell apoptosis was detected by TUNEL assay. Results Compared with the control group, the final body weight and body weight gain were significantly higher in HFD-fed rats, while the testicle/body weight ratios were lower(P < 0.05). In HFD-fed rats, obvious pathological changes in the testicular tissue were observed. Treatment with 4-PBA attenuated HFD-induced histological damage, ameliorated the HFD-induced decrease in serum testosterone(T), and reduced the rate of testicular cell apoptosis(P < 0.05) in obese male rats. Finally, 4-PBA significantly improved semen parameters in HFD rats(P < 0.05). Conclusion HFD exposure induced detrimental effects on spermatogenesis, semen quality, serum T level, and testicular cell apoptosis in rats. Treatment with 4-PBA ameliorated HFD-induced impaired spermatogenesis via inhibition of apoptosis in rats. 4-PBA may have therapeutic value in the treatment of obesity-related impairment of spermatogenesis. | WANG Er Hui YAO San Qiao TAO Ling XI Jin Yan | 2018 | Biomedical and Environmental Sciences2018，31，12： | 0 |
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