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| 1 | Genome-level diversification of eight ancient tea populations in the Guizhou and Yunnan regions identifies candidate genes for core agronomic traits显示文摘The ancient tea plant,as a precious natural resource and source of tea plant genetic diversity,is of great value for studying the evolutionary mechanism,diversification,and domestication of plants.The overall genetic diversity among ancient tea plants and the genetic changes that occurred during natural selection remain poorly understood.Here,we report the genome resequencing of eight different groups consisting of 120 ancient tea plants:six groups from Guizhou Province and two groups from Yunnan Province.Based on the 8,082,370 identified high-quality SNPs,we constructed phylogenetic relationships,assessed population structure,and performed genome-wide association studies(GWAS).Our phylogenetic analysis showed that the 120 ancient tea plants were mainly clustered into three groups and five single branches,which is consistent with the results of principal component analysis(PCA).Ancient tea plants were further divided into seven subpopulations based on genetic structure analysis.Moreover,it was found that the variation in ancient tea plants was not reduced by pressure from the external natural environment or artificial breeding(nonsynonymous/synonymous=1.05).By integrating GWAS,selection signals,and gene function prediction,four candidate genes were significantly associated with three leaf traits,and two candidate genes were significantly associated with plant type.These candidate genes can be used for further functional characterization and genetic improvement of tea plants. | Litang Lu Hufang Chen Xiaojing Wang Yichen Zhao Xinzhuan Yao Biao Xiong Yanli Deng Degang Zhao | 2021 | Horticulture Research2021，8，1： | 3 |
| 2 | Comparative WGBS identifies genes that influence non-ripe phenotype in tomato epimutant Colourless non-ripening显示文摘Whole-genome bisulfite sequencing(WGBS)allows single-base resolution and genome-wide profiling of DNA methylation in plants and animals.This technology provides a powerful tool to identify genes that are potentially controlled by dynamic changes of DNA methylation and demethylation.However,naturally occurring epimutants are rare and genes under epigenetic regulation as well as their biological relevances are often difficult to define.In tomato,fruit development and ripening are a complex process that involves epigenetic control.We have taken the advantage of the tomato epimutant Colourless non-ripening(Cnr)and performed comparative mining of the WGBS datasets for the Cnr and Sl CMT3-silenced Cnr fruits.We compared DNA methylation profiles for the promoter sequences of approximately 5,000 bp immediately upstream of the coding region of a list of20 genes.Differentially methylated regions were found for some of these genes.Virus-induced gene silencing(VIGS)of differentially methylated gene Sl DET1 or Sl PDS resulted in unusual brown pigmentation in Cnr fruits.These results suggest that comparative WGBS coupled with VIGS can be used to identify genes that may contribute to the colourless unripe phenotype of fruit in the Cnr epimutant. | Weiwei Chen Zhiming Yu Junhua Kong Hui Wang Yichen Li Mei Zhao Xiaohong Wang Qianqian Zheng Nongnong Shi Pengcheng Zhang Silin Zhong Paul Hunter Mahmut Tor Yiguo Hong | 2018 | Science China(Life Sciences)2018，61，2： | 3 |
| 3 | A statistical analysis of the freshness of postharvest leafy vegetables with application of water based on chlorophyll fluorescence measurement显示文摘Vegetable freshness is very important for both restaurant and home consumers.In market,sellers frequently apply water to leafy vegetables to make them not lose weight and look fresh;however,these vegetables may not be stored for a long time as they appear.After a time limit,they may be quickly rotten.It is thus meaningful to investigate early and simple detection tools to measure leafy vegetable freshness while they are frequently applied water in selling.In this work,three types of newly harvested leafy vegetables were bought from a local farmer market and stored in the air with room temperature and roots submerging in water.Chlorophyll a fluorescence(ChlF)from the vegetables was measured each half a day for three days.The obtained ChlF data were analyzed statistically and the correlation of ChlF parameters and vegetable freshness/storage time was obtained.The k-mean classification was also performed.It is found that Fo,Fj,Fm/Fo,and Fv/Fm can be used as an early detection tool to differentiate the freshness of leafy vegetables on which water is constantly applied in storage without visible difference. | Yichen Qiu Yuhang Zhao Juan Liu Ya Guo | 2017 | Information Processing in Agriculture2017，4，4： | 2 |
| 4 | Analysis of oral microorganism diversity in healthy individuals before and after chewing areca nuts using PCR-denatured gradient gel electrophoresis显示文摘To analyze oral microbial diversity in the saliva of 8 healthy individuals before and after chewing areca nuts. Saliva samples were collected before chewing areca nuts, after chewing areca nuts for 5 min and after chewing areca nuts for 30 min. DNA was extracted, and microbial diversity was examined using PCR-denaturing gradient gel electrophoresis(PCR-DGGE). When examining DGGE profiles collectively,the bands associated with Streptococcus and Veillonella were the most intense, making them the most prevalent bacteria. Furthermore, the band intensities did not decrease after chewing areca nuts for 5 or30 min; thus, these bacteria were unaffected. However, when examining some individuals, the band intensities for Streptococcus and Veillonella became more intense after 5 min of chewing and then returned to the pre-chewing level. This difference may be attributed to the mechanical movements of the oral cavity or individual differences. Other bacteria, such as Neisseria, Actinomycetes, and Rothia dentocariosa, were also found to have an increased or decreased prevalence following areca nut-chewing.Since the predominant species that are present following areca nut-chewing include Streptococcus and Veillonella, it would seem likely that these bacteria play an important role in the periodontal diseases associated with areca chewing. | Xiong Xiong Aixiang Hou Shuhan Yi Yichen Guo Ziwei Zhao Zhongkun Wu Huan Cheng Ke Li Zongjun Li Youhua Ren Yuanliang Wang | 2018 | Animal Nutrition2018，，3： | 2 |
| 5 | The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease显示文摘Mammary and extramammary Paget’s Diseases(PD)are a malignant skin cancer characterized by the appearance of Paget cells.Although easily diagnosed,its pathogenesis remains unknown.Here,single-cell RNA-sequencing identified distinct cellular states,novel biomarkers,and signaling pathways—including mTOR,associated with extramammary PD.Interestingly,we identified MSI1 ectopic overexpression in basal epithelial cells of human PD skin,and show that Msi1 overexpression in the epidermal basal layer of mice phenocopies human PD at histopathological,single-cell and molecular levels.Using this mouse model,we identified novel biomarkers of Paget-like cells that translated to human Paget cells.Furthermore,single-cell trajectory,RNA velocity and lineage-tracing analyses revealed a putative keratinocyte-to-Paget-like cell conversion,supporting the in situ transformation theory of disease pathogenesis.Mechanistically,the Msi1-mTOR pathway drives keratinocyte-Paget-like cell conversion,and suppression of mTOR signaling with Rapamycin significantly rescued the Paget-like phenotype in Msi1-overexpressing transgenic mice.Topical Rapamycin treatment improved extramammary PD-associated symptoms in humans,suggesting mTOR inhibition as a novel therapeutic treatment in PD. | Yongli Song Christian F.Guerrero-Juarez Zhongjian Chen Yichen Tang Xianghui Ma Cong Lv Xueyun Bi Min Deng Lina Bu Yuhua Tian Ruiqi Liu Ran Zhao Jiuzhi Xu Xiaole Sheng Sujuan Du Yeqiang Liu Yunlu Zhu Shi-jun Shan Hong-duo Chen Yiqiang Zhao Guangbiao Zhou Jianwei Shuai Fazheng Ren Lixiang Xue Zhaoxia Ying Xing Dai Christopher J.Lengner Bogi Andersen Maksim V.Plikus Qing Nie Zhengquan Yu-Show | 2020 | Cell Research2020，30，10： | 2 |
| 6 | Strong partitioning of soil bacterial community composition and co-occurrence networks along a small-scale elevational gradient on Zijin Mountain显示文摘The elevational distributions of bacterial communities in natural mountain forests,especially along large elevational gradients,have been studied for many years.However,the distributional patterns that underlie variations in soil bacterial communities along small-scale elevational gradients in urban ecosystems are not yet well understood.Using Illumina MiSeq DNA sequencing,we surveyed soil bacterial communities at three elevations on Zijin Mountain in Nanjing City:the hilltop(300 m a.s.l.),the hillside(150 m a.s.l.),and the foot of the hill(0 m a.s.l.).The results showed that edaphic properties differed significantly with elevation.Bacterial community composition,rather than alpha diversity,strongly differed among the three elevations(Adonis:R2=0.12,P<0.01).Adonis and DistLM analyses demonstrated that bacterial community composition was highly correlated with soil pH,elevation,total nitrogen(TN),and dissolved organic carbon(DOC).The degree scores,betweenness centralities,and composition of keystone species were distinct among the elevations.These results demonstrate strong elevational partitioning in the distributions of soil bacterial communities along the gradient on Zijin Mountain.Soil pH and elevation together drove the smallscale elevational distribution of soil bacterial communities.This study broadens our understanding of distribution patterns and biotic co-occurrence associations of soil bacterial communities from large elevational gradients to short elevational gradients. | Xu Liu Teng Yang Yu Shi Yichen Zhu Mulin He Yunke Zhao Jonathan MAdams Haiyan Chu | 2021 | Soil Ecology Letters2021，3，4： | 2 |
| 7 | MicroRNA-9 as a paradoxical but critical regulator of cancer metastasis:Implications in personalized medicine显示文摘Metastasis,is a development of secondary tumor growths at a distance from the primary site,and closely related to poor prognosis and mortality.However,there is still no effective treatment for metastatic cancer.Therefore,there is an urgent need to find an effective therapy for cancer metastasis.Plenty of evidence indicates that miR-9 can function as a promoter or suppressor in cancer metastasis and coordinate multistep of metastatic process.In this review,we summarize the different roles of miR-9 with the corresponding molecular mechanisms in metastasis of twelve common cancers and the multiple mechanisms underlying miR-9-mediated regulation of metastasis,benefiting the further research of miR-9 and metastasis,and hoping to bridge it with clinical applications. | Yichen Liu Qiong Zhao Tao Xi Lufeng Zheng Xiaoman Li | 2021 | Genes & Diseases2021，8，6： | 2 |
| 8 | Random distributed logistic regression framework for predicting potential lncRNA-disease association显示文摘Predicting potential lncRNA-disease association pairs is an important issue in the field of biomedicine.Traditional lncRNA-disease association prediction algorithms are mainly based on biological network models.For instance,RWRlncD is developed for predicting the potential lncRNA-disease association by performing random walk with restart on lncRNA functionally similar networks(Sun et al.,2014).However,biological graph network algorithms often have certain limitations and low accuracy.With the development of machine learning,new ideas have been brought to the construction of the association prediction algorithm(Liu et al.,2016,2019a,b;Wan et al.,2019). | Yichen Sun Hongqian Zhao Gang Zhou Tianhao Guan Yujie Wang Jie Gao | 2021 | Journal of Molecular Cell Biology2021，13，5： | 1 |
| 9 | Sugar transfer of nanomaterials and flexible electrodes显示文摘Nanomaterials with various dimensionalities(e.g.,nanowires,nanofilms,two-dimensional materials,and three-dimensional nanostructures)have shown great potential in the recent development of flexible electronics.Conventionally,organic solvents are inevitable while integrating nanomaterials onto flexible substrates,where polymer mediator-assisted transfer techniques are involved.This often damages the flexible substrate and thus hamper the large-scale application of nanomaterials.Here we report a method using watersoluble sugar as a mediator to facilely transfer nanomaterials onto rigid or flexible substrates.This method requires no organic solvent during transfer.More importantly,the morphology and properties of transferred nanomaterials,such as shape,microstructure,resistivity,and transmittance are well preserved on the target substrate.We believe that this universal and rapid transfer method can greatly advance the applications of nanomaterials in the field of flexible devices and beyond. | Tianzeng Hong Tianze Shen Junlong Yang Yichen Sun Jianming Zhang Haiyang Pan Ying Hong Yan Wang Shuo Chen Yue Zhao Chuan Fei Guo | 2020 | International Journal of Smart and Nano Materials2020，11，1： | 1 |
| 10 | DualFace:Two-stage drawing guidance for freehand portrait sketching显示文摘Special skills are required in portrait painting, such as imagining geometric structures and facial detail for final portrait designs. This makes it a difficult task for users, especially novices without prior artistic training, to draw freehand portraits with high-quality details. In this paper, we propose dualFace, a portrait drawing interface to assist users with different levels of drawing skills to complete recognizable and authentic face sketches. Inspired by traditional artist workflows for portrait drawing, dualFace gives two-stages of drawing assistance to provide global and local visual guidance. The former helps users draw contour lines for portraits (i.e., geometric structure), and the latter helps users draw details of facial parts, which conform to the user-drawn contour lines. In the global guidance stage, the user draws several contour lines, and dualFace then searches for several relevant images from an internal database and displays the suggested face contour lines on the background of the canvas. In the local guidance stage, we synthesize detailed portrait images with a deep generative model from user-drawn contour lines, and then use the synthesized results as detailed drawing guidance. We conducted a user study to verify the effectiveness of dualFace, which confirms that dualFace significantly helps users to produce a detailed portrait sketch. | Zhengyu Huang Yichen Peng Tomohiro Hibino Chunqi Zhao Haoran Xie Tsukasa Fukusato Kazunori Miyata | 2022 | Computational Visual Media2022，8，1： | 1 |
| 11 | Population Structure Analysis and Genome-Wide Association Study of Tea(Camellia sinensis(L.)Kuntze)Germplasm in Qiannan,China,Based on SLAF-Seq Technology显示文摘Duyun Maojian tea is a famous tea in China.In this study,the specific-locus amplified fragment(SLAF)sequencing method was used to analyze the population structure and conduct a genome-wide association study(GWAS)of 2 leaf traits of 123 tea plants in Qiannan,China.A total of 462,019 SLAF tags and 11,362,041 single-nucleotide polymorphism(SNP)loci were obtained.The results of phylogenetic tree analysis,cluster analysis,and principal component analysis showed that 123 tea germplasms were clustered into three groups,and the heterozygosity rates for Groups I,II,and II were 0.206,0.224,and 0.34,respectively.Generally,tea germplasms in a production area are clustered in a group,indicating that tea germplasms in different production areas have certain genetic diversity.The traditional Duyun Maojian tea core production areas,TS and DC-SJ,are clustered into Group I and Group II respectively,while the ZY production area is relatively independent in Group III.Furthermore,based on GWAS analysis,11 candidate genes related to leaf apex and 7 candidate genes related to leaf shape were obtained.This study clarified the genetic relationship among eight Duyun Maojian tea production areas and obtained candidate genes related to leaf apex and leaf shape development.The results showed that population structure and candidate genes are an effective basis for the breeding of Duyun Maojian tea germplasm. | Fen Zhang Weili Tian Lu Cen Litang Lv Xiaofang Zeng Yulu Chen Yichen Zhao Yan Li | 2022 | Phyton-International Journal of Experimental Botany2022，91，4： | 1 |
| 12 | A comprehensive evaluation of flowering plant diversity and conservation priority for national park planning in China显示文摘Establishment of a national park protection system in China,including the latest target proposed to protect at least 30%of the land area,calls for a comprehensive exploration of conservation priorities incorporating multiple diversity facets.We herein evaluate the spatial distribution of Chinese flowering plants from the perspectives of richness,uniqueness,vulnerability,and evolutionary history,by integrating three mega-phylogenies and comprehensive distribution data.We detect significantly high consistency among hotspots of different diversity measures for Chinese flowering plants,suggesting that multiple facets of evolutionary diversity are concentrically distributed in China.Affording legal protection to these areas is expected to maximize positive conservation outcomes.We propose two integrative diversity indices by incorporating three richness-based and three phylogeny-based measures,respectively.Both methods identify areas with high species richness,but the integrative phylogeny-based index also locates key areas with ancient and unique evolutionary histories(e.g.,Ailao-Wuliang Mts,Dabie Mts,Hainan rainforest,Karst area of Yunnan-Guizhou-Guangxi,Nanling Mts,and southeast coastal regions).Of all the diversity indices explored,phylogenetic endemism maximizes the incidental protection of other indices in most cases,emphasizing its significance for conservation planning.Finally,42 priority areas are identified by combining the 5%-criterion hotspots of two integrative indices and the minimum area to protect all threatened species analyzed.These priorities cover only 13.3%of China's land area,but host 97.1%of species richness(23,394/24,095),96.5%of endemic species(11,841/12,274),100%of threatened species(2,613/2,613),and 99.3%of phylogenetic diversity for flowering plants involved in this study.These frameworks provide a solid scientific basis for national park planning in China. | Limin Lu Lina Zhao Haihua Hu Bing Liu Yuchang Yang Yichen You Danxiao Peng Russell L.Barrett Zhiduan Chen | 2023 | Fundamental Research2023，3，6： | 1 |
| 13 | A social computing method for energy safety显示文摘Information and communication technologies enable the transformation of traditional energy systems into cyber-physical energy systems(CPESs),but such systems have also become popular targets of cyberattacks.Currently,available methods for evaluating the impacts of cyberattacks suffer from limited resilience,efficacy,and practical value.To mitigate their potentially disastrous consequences,this study suggests a two-stage,discrepancy-based optimization approach that considers both preparatory actions and response measures,integrating concepts from social computing.The proposed Kullback-Leibler divergence-based,distributionally robust optimization(KDR)method has a hierarchical,two-stage objective function that incorporates the operating costs of both system infrastructures(e.g.,energy resources,reserve capacity)and real-time response measures(e.g.,load shedding,demand-side management,electric vehicle charging station management).By incorporating social computing principles,the optimization framework can also capture the social behavior and interactions of energy consumers in response to cyberattacks.The preparatory stage entails day-ahead operational decisions,leveraging insights from social computing to model and predict the behaviors of individuals and communities affected by potential cyberattacks.The mitigation stage generates responses designed to contain the consequences of the attack by directing and optimizing energy use from the demand side,taking into account the social context and preferences of energy consumers,to ensure resilient,economically efficient CPES operations.Our method can determine optimal schemes in both stages,accounting for the social dimensions of the problem.An original disaster mitigation model uses an abstract formulation to develop a risk-neutral model that characterizes cyberattacks through KDR,incorporating social computing techniques to enhance the understanding and response to cyber threats.This approach can mitigate the impacts more effectively than several existing methods,even with limited data availability.To extend this risk-neutral model,we incorporate conditional value at risk as an essential risk measure,capturing the uncertainty and diverse impact scenarios arising from social computing factors.The empirical results affirm that the KDR method,which is enriched with social computing considerations,produces resilient,economically efficient solutions for managing the impacts of cyberattacks on a CPES.By integrating social computing principles into the optimization framework,it becomes possible to better anticipate and address the social and behavioral aspects associated with cyberattacks on CPESs,ultimately improving the overall resilience and effectiveness of the system’s response measures. | Pengfei Zhao Shuangqi Li Zhidong Cao Paul Jen-Hwa Hu Daniel Dajun Zeng Da Xie Yichen Shen Jiangfeng Li Tianyi Luo | 2024 | Journal of Safety Science and Resilience2024，5，1： | 0 |
| 14 | Survey on rain removal from videos or a single image显示文摘Rain can cause performance degradation of outdoor computer vision tasks.Thus,the exploration of rain removal from videos or a single image has drawn considerable attention in the field of image processing.Recently,various deraining methodologies have been proposed.However,no comprehensive survey work has yet been conducted to summarize existing deraining algorithms and quantitatively compare their generalization ability,and especially,no off-the-shelf toolkit exists for accumulating and categorizing recent representative methods for easy performance reproduction and deraining capability evaluation.In this regard,herein,we present a comprehensive overview of existing video and single image deraining methods as well as reproduce and evaluate current state-of-the-art deraining methods.In particular,these approaches are mainly classified into model-and deep-learning-based methods,and more elaborate branches of each method are presented.Inherent abilities,especially generalization performance,of the state-of-the-art methods have been both quantitatively and visually analyzed through thorough experiments conducted on synthetic and real benchmark datasets.Moreover,to facilitate the reproduction of existing deraining methods for general users,we present a comprehensive repository with detailed classification,including direct links to 85 deraining papers,24 relevant project pages,source codes of 12 and 25 algorithms for video and single image deraining,respectively,5 and 10 real and synthesized datasets,respectively,and 7 frequently used image quality evaluation metrics,along with the corresponding computation codes.Research limitations worthy of further exploration have also been discussed for future research along this direction. | Hong WANG Yichen WU Minghan LI Qian ZHAO Deyu MENG | 2022 | Science China(Information Sciences)2022，65，1： | 0 |
| 15 | Capture-SELEX for Chloramphenicol Binding Aptamers for Labeled and Label-Free Fluorescence Sensing显示文摘Chloramphenicol(CAP)is a potent antibiotic.Due to its side effects,CAP is currently banned in most countries,but it is still found in many food products and in the environment.Developing aptamer-based biosensors for the detection of CAP has interested many researchers.While both RNA and DNA aptamers were previously reported for CAP,they were all obtained by immobilization of the CAP base,which omitted the two chlorine atoms.In this work,DNA aptamers were selected using the libraryimmobilized method and free unmodified CAP.Three families of aptamers were obtained,and the best one named CAP1 showed a dissociation constant(K_(d))of 9.8μM using isothermal titration calorimetry(ITC).A fluorescent strand-displacement sensor showed a limit of detection(LOD)of 14μM CAP.Thioflavin T(ThT)staining allowed label-free detection of CAP with a LOD of 1μM in buffer,1.8μM in Lake Ontario water,and 3.6μM in a wastewater sample.Comparisons were made with previously reported aptamers,and ITC failed to show binding of a previously reported 80-mer aptamer.Due to the small size and well-defined secondary structures of CAP1,this aptamer will find analytical applications for environmental and food monitoring. | Yichen Zhao Albert Zehan Li Juewen Liu | 2023 | Environment & Health2023，1，2： | 0 |
| 16 | Efficacy of Zhumian Tang formula granules(助眠汤配方颗粒)combined with eszopiclone for the treatment of poor sleep quality:a multi-center,randomized controlled,superiority trial显示文摘OBJECTIVE:To evaluate the efficacy and safety of Zhumian Tang formula granules(助眠汤配方颗粒)combined with eszopiclone for treating poor sleep quality.METHODS:This multi-center,dynamic blockrandomized,parallel-group superiority clinical trial included 130 patients.The combined treatment group received Zhumian Tang formula granules combined with eszopiclone treatment,and the control group received eszopiclone treatment only.The group allocation ratio was 1∶1.The duration of treatment was 2 weeks.Participants were asked to complete questionnaires before treatment,after 1 week of the intervention,after 2 weeks of the intervention,and at the follow-up on week 3.The primary outcomes were the Pittsburgh Sleep Quality Index(PSQI)score and the total effective rate of treatment.The secondary outcome was the rate of adverse effects.RESULTS:Compared with the eszopiclone treatment group,the PSQI score of the combined treatment group was significantly lower after 2 weeks of the intervention(6.98 vs 8.26,P<0.05).However,there was no significant difference in the mean PSQI score after 1 week of the intervention(9.89 vs 9.15,P=0.124).After the follow-up on week 3,the PSQI score of the combined treatment group remained significantly lower than that of the eszopiclone treatment group(6.12 vs 8.31,P<0.001).The total effective rates of treatment of the combined group and the eszopiclone group were 36.92%vs 35.38%(Z=0.033,P=0.855)after 1 week of the intervention,83.08%vs 58.46%(Z=9.519,P<0.05)after 2 weeks of the intervention,and 83.08%vs 61.54%(Z=7.530,P<0.05)and after the follow-up on week 3,respectively.There was no significant difference in the overall rate of adverse reactions between the combined and eszopiclone treatment groups(21.53%vs 31.8%,P=0.318).CONCLUSION:The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone alone.Traditional Chinese medicine can enhance the effectiveness of Western medicine in the treatment of insomnia. | WANG Yichen WU Shiyi WANG Zhengyan CHANG Wenling XIE Zhihao TANG Xing ZHAO Songmei ZHOU Jing CHEN Zehong WANG Chao() YANG Chunxia | 2024 | Journal of Traditional Chinese Medicine2024，44，1： | 0 |
| 17 | Design strategies for rechargeable aqueous metal-ion batteries显示文摘Rechargeable aqueous metal-ion batteries(AMBs)have attracted extensive scientific and commercial interest due to their potential for cost-effective,highly safe,and scalable stationary energy storage.However,their limited output voltage,inadequate energy density,and poor reversibility of ambiguous electrode reactions in aqueous electrolytes strongly limit their practical viability.This review aims to elucidate the challenges of existing AMBs from the material design to whole device applications.We summarize the emerging electrochemistry,fundamental properties,and key issues in interfacial behaviors of various classes of prevailing AMBs,including aqueous alkali metal-ion batteries and multivalent-ion batteries,and present an appraisal of recent advances for addressing the performance deficiency.Specifically,the progress of zinc-ion batteries is highlighted to provide a ubiquitous guideline for their commercialization in the grid-scale energy storage.Finally,we figure out the dominating general challenges for achieving high-performance AMBs,laying out a perspective for future breakthroughs. | Yang Li Xin Zhao Yifu Gao Yichen Ding Zhichun Si Liubing Dong Dong Zhou Feiyu Kang | 2024 | Science China Chemistry2024，67，1： | 0 |
| 18 | Three-Dimensional M-Shaped Resection for Nasal Alar Hypertrophy in Asian Patients显示文摘Background Nasal alarplasty is an important component of esthetic rhinoplasty in Asians.The two main surgical techniques that correct alar hypertrophy by reducing the height or length often leave external scars and are associated with a high relapse rate.Methods We developed a new technique,called three-dimensional(3D)M-shaped resection,which corrects both the nasal alar height and length and simultaneously minimizes external scarring.We performed this procedure from January 2013 to September 2016 in 49 consecutive female patients diagnosed with saddle nose and nasal alar hypertrophy.Their mean age was 28.6(range,18–40)years.All patients had previously undergone simple rhinoplasty.Nasal alar length and height,nostril length and width,and maximal nose width were analyzed preoperatively and postoperatively from photographs.Results After a mean of 9(range,3–24)months of follow-up,surgery was considered successful in 46 women(94%)with good cosmetic effects.In three patients,nasal alar hypertrophy recurred(6 months postoperatively).There were no early complications such as hematomas,infections,skin or mucosal necrosis,or wound dehiscence.The mean reductions postoperatively were 1.7 mm and 0.9 mm for nasal alar length and height,respectively,1.6 mm for both nostril length and width,and 3.5 mm for nose width.Conclusion The 3D M-shaped resection for nasal alar hypertrophy effectively reduced hypertrophy in 94%of patients for up to 24 months,producing minimal external scars and good cosmetic effects.It is a simple and convenient technique that is an effective and safe option for nasal alarplasty. | Yiqing QIU Qingfang ZHAO Zhixiong CHEN Yichen SHEN Mengmeng LUO Qiaoyun QIU Jinghong XU | 2021 | Chinese Journal Of Plastic and Reconstructive Surgery2021，3，1： | 0 |
| 19 | Cloning and Characterization of EuGID1 in Eucommia ulmoides Oliver显示文摘Gibberellic acid controlled the key developmental processes of the life cycle of landing plants,and regulated the growth and development of plants.In this study,a novel gibberellin receptor gene EuGID1 was obtained from Eucommia ulmoides Oliver.The cDNA of EuGID1 was 1556 bp,and the open reading frame was 1029 bp,which encoded 343 amino acids.EuGID1 had the homology sequence with the hormone-sensitive lipase family.Amino acid sequence alignment confirmed EuGID1 protein had the highest homology with the GID1 protein of Manihot esculenta.EuGID1 was located in the nucleus and cell membrane and had expression in four plant organs.Overexpression of EuGID1 in transgenic Arabidopsis plants promoted plant elongation and increased siliques yield. | Yulu Chen Fen Zhang Ju Cai Yichen Zhao Jiaxue Cui Yan Li | 2022 | Phyton-International Journal of Experimental Botany2022，91，5： | 0 |
| 20 | Image Segmentation via Fischer-Burmeister Total Variation and Thresholding显示文摘Image segmentation is a significant problem in image processing.In this paper,we propose a new two-stage scheme for segmentation based on the Fischer-Burmeister total variation(FBTV).The first stage of our method is to calculate a smooth solution from the FBTV Mumford-Shah model.Furthermore,we design a new difference of convex algorithm(DCA)with the semi-proximal alternating direction method of multipliers(sPADMM)iteration.In the second stage,we make use of the smooth solution and the K-means method to obtain the segmentation result.To simulate images more accurately,a useful operator is introduced,which enables the proposed model to segment not only the noisy or blurry images but the images with missing pixels well.Experiments demonstrate the proposed method produces more preferable results comparing with some state-of-the-art methods,especially on the images with missing pixels. | TingtingWu Yichen Zhao Zhihui Mao Li Shi Zhi Li Yonghua Zeng | 2022 | Advances in Applied Mathematics and Mechanics2022，14，4： | 0 |
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