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| 1 | Hydrology and water resources variation and its response to regional climate change in Xinjiang显示文摘Based on the surface runoff, temperature and precipitation data over the last 50 years from eight representative rivers in Xinjiang, using Mann-Kendall trend and jump detection method, the paper investigated the long-term trend and jump point of time series, the surface runoff, mean annual temperature and annual precipitation. Meanwhile, the paper analyzed the relationship between runoff and temperature and precipitation, and the flood frequency and peak flow. Results showed that climate of all parts of Xinjiang conformably has experienced an increase in temperature and precipitation since the mid-1980s. Northern Xinjiang was the area that changed most significantly followed by southern and eastern Xinjiang. Affected by temperature and precipitation variation, river runoff had changed both inter-annually and intra-annually. The surface runoff of most rivers has increased significantly since the early 1990s, and some of them have even witnessed the earlier spring floods, later summer floods and increasing flood peaks. The variation characteristics were closely related with the replenishment types of rivers. Flood frequency and peak flow increased all over Xinjiang. Climate warming has had an effect on the regional hydrological cycle. | XU Changchun CHEN Yaning YANG Yuhui HAO Xingming SHEN Yongping | 2010 | Journal of Geographical Sciences2010，20，4： | 17 |
| 2 | Lipids and membrane-associated proteins in autophagy显示文摘Autophagy is essential for the maintenance of cellular homeostasis and its dysfunction has been linked to various diseases.Autophagy is a membrane driven process and tightly regulated by membrane-associated proteins.Here,we summarized membrane lipid composition,and membrane-associated proteins relevant to autophagy from a spatiotemporal perspective.In particular,we focused on three important membrane remodeling processes in autophagy,lipid transfer for phagophore elongation,membrane scission for phago-phore closure,and autophagosome-lysosome membrane fusion.We discussed the significance of the discoveries in this field and possible avenues to follow for future studies.Finally,we summarized the membrane-associated biochemical techniques and assays used to study membrane properties,with a discussion of their applications in autophagy. | Linsen Li Mindan Tong Yuhui Fu Fang Chen Shen Zhang Hanmo Chen Xi Ma Defa Li Xiaoxia Liu Qing Zhong | 2021 | Protein & Cell2021，12，7： | 3 |
| 3 | Selective propylene epoxidation in liquid phase using highly dispersed Nb catalysts incorporated in mesoporous silicates显示文摘Selective propylene epoxidation to propylene oxide(PO) with hydrogen peroxide(H_2O_2) was carried out in a catalytic semi-batch reactor.High propylene epoxidation activity(44 h^(-1)) was observed over Nb based mesoporous silicate materials Nb-TUD-1 under mild operating conditions.The physical and chemical properties of the Nb based silicates characterized using BET,FTIR,TPD,TEM and UV–Vis revealed that the site isolation and surface acidity are crucial for PO production.Catalyst synthesis methods were investigated for their effects on PO productivity,PO selectivity and H_2O_2 utilization efficiency.It is found that Nb-TUD-1 material synthesized by the sol–gel method is more active and selective than impregnated materials for liquid phase propylene epoxidation.Surface characterization confirms that thus synthesized Nb-TUD-1 catalysts have more Lewis acidity and less Bronsted acidity compared to the catalysts by impregnation. | Wenjuan Yan Yuhui Wu Xiang Feng Chaohe Yang Xin Jin Jian Shen | 2018 | Chinese Journal of Chemical Engineering2018，26，6： | 1 |
| 4 | Interfacial pH: a criti-cal factor for osteoporotic bone regeneration显示文摘 | Yuhui Shen HaoboPan William W Lu | 2011 | Langmuir2011，27，： | 1 |
| 5 | An iterative data-driven turbulence modeling framework based on Reynolds stress representation显示文摘Data-driven turbulence modeling studies have reached such a stage that the basic framework is settled,but several essential issues remain that strongly affect the performance.Two problems are studied in the current research:(1)the processing of the Reynolds stress tensor and(2)the coupling method between the machine learning model and flow solver.For the Reynolds stress processing issue,we perform the theoretical derivation to extend the relevant tensor arguments of Reynolds stress.Then,the tensor representation theorem is employed to give the complete irreducible invariants and integrity basis.An adaptive regularization term is employed to enhance the representation performance.For the coupling issue,an iterative coupling framework with consistent convergence is proposed and then applied to a canonical separated flow.The results have high consistency with the direct numerical simulation true values,which proves the validity of the current approach. | Yuhui Yin Zhi Shen Yufei Zhang Haixin Chena Song Fu | 2022 | Theoretical & Applied Mechanics Letters2022，12，5： | 1 |
| 6 | Multispectroscopic studies for the identification of archaeological frankincense excavated in the underground palace of Bao’en Temple, Nanjing: near infrared, midinfrared, and Raman spectroscopies显示文摘 | Lei Zhou Dawa Shen Junquan He Yuhui Wei Qinglin Ma Zhide Hu | 2012 | J Raman Spectrosc2012，，10： | 1 |
| 7 | Synthesis of ultra-high molecular weight polystyrene with rare eath-magnesium alkyl catalyst system:general features of bulk polymerization显示文摘 | Shen Zhiquan Yang Yuhui | 2001 | Polym Int2001，50，1： | 1 |
| 8 | Primary clear cell sarcoma of the sacrum:a case report显示文摘 | Weibin Zhang Yuhui Shen Rong Wan | 2011 | Skeletal Radiol2011，40，5： | 1 |
| 9 | Overview of control-centric integrated design for hypersonic vehicles显示文摘Hypersonic vehicles(HSVs)exhibit significant advantages over other vehicles,including the wide range of velocity and large airspace types,and these features have contributed to the rapid development of HSVs in the last 20 years.Moreover,hypersonic technologies have become a multidisciplinary research topic in the fields of aerodynamics,propulsion,structure,material,and control.Different types of re-entry gliding,air-breathing cruise,and aerospace vehicles have been designed to realize ambitious tasks,which in turn influenced the technological advancements and process change in the military.This paper summarizes the control-oriented integrated design of HSVs.First,the status of current research on the distinct characteristics and technique issues of HSVs is introduced.Then,the progresses made on complex modeling,guidance and control,and trajectory optimization are elaborated to exhibit the significant research interest in hypersonic technologies.The control-integrated design of HSVs is emphasized to solve the multidisciplinary design problems associated with the model and its control and trajectory.Various strategies regarding the multidisciplinary optimization design are also proposed to solve the integrated design problem.Finally,suggestions are provided for the control-oriented integrated design of HSVs. | Yanbin Liu Boyi Chen Yuhui Li Haidong Shen | 2018 | Astrodynamics2018，2，4： | 1 |
| 10 | Myosin 1D and the branched actin network control the condensation of p62 bodies显示文摘Biomolecular condensation driven by liquid-liquid phase separation(LLPS)is key to assembly of membraneless organelles in numerous crucial pathways.It is largely unknown how cellular structures or components spatiotemporally regulate LLPS and condensate formation.Here we reveal that cytoskeletal dynamics can control the condensation of p62 bodies comprising the autophagic adaptor p62/SQSTM1 and poly-ubiquitinated cargos.Branched actin networks are associated with p62 bodies and are required for their conden satio n.Myosi n 1D,a bran ched acti n-associated motor protein,drives coalesce nee of small nano scale p62 bodies into large micron-scale condensates along the branched actin network.Impairment of actin cytoskeletal networks compromises the condensation of p62 bodies and retards substrate degradation by autophagy in both cellular models and Myosin ID knockout mice.Coupling of LLPS scaffold to cytoskeleton systems may represent a general mechanism by which cells exert spatiotemporal control over phase condensation processes. | Xuezhao Feng Wanqing Du Mingrui Ding Wenkang Zhao Xirenayi Xirefu Meisheng Ma Yuhui Zhuang Xiaoyu Fu Jiangfeng Shen Jinpei Zhang Xiuying Lei Daxiao Sun Qing Xi Yiliyasi Aisa Qian Chenr Ying Li Wenjuan Wang Shanjin Huang Li Yu Pilong Li Na Mi | 2022 | Cell Research2022，32，7： | 1 |
| 11 | IKKα Shields 14-3-3σ , a G 2 /M Cell Cycle Checkpoint Gene, from Hypermethylation, Preventing Its Silencing显示文摘 | Feng Zhu Xiaojun Xia Bigang Liu Jianjun Shen Yuhui Hu Maria Person Yinling Hu | 2007 | Molecular Cell2007，，： | 1 |
| 12 | Effects of strontium in modified biomaterials显示文摘 | Weibin Zhang Yuhui Shen Haobo Pan Kaili Lin Xiaoguo Liu Brian W. Darvell William W. Lu Jiang Chang Lianfu Deng Deping Wang Wenhai Huang | 2010 | Acta Biomaterialia2010，，2： | 1 |
| 13 | QSAR research of the activity of span surfaetants as wax antisettling additives for diesel显示文摘 | Gu Yuhui Shen Benxian | 2006 | Energy & Fuels2006，20，4： | 1 |
| 14 | Subsurface banding of blended controlled-release urea can optimize rice yields while minimizing yield-scaled greenhouse gas emissions显示文摘Controlled-release urea(CRU)is widely reported to supply crop nitrogen(N)demand with one basal application,thus effectively replacing split applications of urea without diminishing grain yield and N use efficiency(NUE).However,its use for replacement for high-yield split applications of urea(CK)for rice is untested.In addition,the degree to which greenhouse gas(GHG)emissions in rice systems are affected when CRU is substituted for CK remains unclear.During 2017 and 2018,we sampled plant growth and gas emissions in a rice paddy field treated with three CRU types(sulfur-coated urea[SCU],polymer-coated urea[PCU],and bulk blended CRU[BBU])applied via two methods(surface broadcasting on the soil and subsurface banding at 5 cm depth),with CK as a control.The three CRUs led to different soil NH_(4)^(+)-N dynamics,and the N supply pattern under BBU was more beneficial for rice seedling establishment than under SCU and PCU,resulting in grain yield and NUE comparable to those under CK.CRU type showed no significant effect on either CH_(4) emissions or N_(2)O emissions,and broadcast CRUs exhibited significantly higher total GHG emissions than CK.However,banded CRUs significantly reduced the total GHG emissions in comparison with broadcast CRUs,by 9.2%averaged across the two years.Reduced CH_(4) emissions,particularly during the period prior to the middle drainage,contributed largely to the GHG difference.With comparably high grain yield and low total GHG emissions,banded BBU showed a low yield-scaled GHG(GHG emissions divided by grain yield)comparable to that under CK in both years.Overall,our study suggested that N management synchronized with rice demand and contributing to a high NUE tended to minimize yield-scaled GHG.Broadcast CRU can hardly substitute for CK in terms of either grain yield or GHG emissions,but banded BBU is a promising N management strategy for sustaining rice production while minimizing environmental impacts. | Weiwei Li Sajjad Ahmad Dun Liu Shen Gao Yuhui Wang Weike Tao Lin Chen Zhenghui Liu Yu Jiang Ganghua Li Yanfeng Ding | 2023 | The Crop Journal2023，11，3： | 0 |
| 15 | Perceiving the connection between the bone healing process and biodegradation of biodegradable metal implants through precise bioadaptability principle显示文摘The implants made of metallic biomaterials help healing the bone fracture but also affect the bone repair process.As proposed in Matter 4(2021)2548–2650 by Wang et al.,a precisely adaptable biomaterial ought to recapitulate the targeted tissue with spatiotemporal precision and hierarchical accuracy,ranging from atoms and molecules(genes,proteins,etc.)to cells(including organelles)and to tissues and organs.In comparison to traditional bio-inert metallic bone implants such as Co-based alloys and Ti alloys,biodegradable metal(Mg and Zn alloys)bone implants had been developed and might arise many unexpected variables in the bone repair,due to their bioactive nature.In this paper,the bone repair without and with the presence of metallic implants is compared.Thereafter,the perspectives concerning the interactions between the bone tissues and biodegradable metal implants are put forward,and how to better mimic in vivo biodegradation by in vitro experiments is proposed for further research and development of biodegradable metals. | Yufeng Zheng Xiao Liu Danni Shen Wenting Li Yan Cheng Ming Yang Yuhui Kou Baoguo Jiang | 2023 | Journal of Materials Science & Technology2023，，16： | 0 |
| 16 | Total Synthesis of Stemarene and Betaerene Diterpenoids:Divergent Ring-Formation Strategy and Late-Stage C–H Functionalization显示文摘A unified protecting group-free approach to two stemarene and two betaerene diterpenoids through a bioinspired two-phase strategy has been developed,and three of them were obtained for the first time via chemical synthesis.Starting from a common intermediate,two distinct tetracyclic frameworks containing diastereoisomeric bridged bicycles were constructed by a divergent ring reorganization strategy.Late-stage C–H functionalization through a xanthylation-oxygenation protocol furnished the corresponding oxygenated stereocenters or oxo functionality in high regio-and diastereoselective fashion within a complex hydrocarbon system.The stereochemical puzzles in(–)-2-acetoxybetaer13(17)-ene and(+)-7-acetoxybetaer-13(17)-ene were first predicted by the comparison of density functional theory(DFT)-nuclear magnetic resonance(NMR)data with the reported data and then unambiguously addressed through the total syntheses of natural products and three diastereomers. | Renzhi Chen Feng Zhang Yuhui Hua Dong Shi Xin Lei Hongxiu Xiao Yinong Wang Shihao Ding Yang Shen Yandong Zhang | 2022 | CCS Chemistry2022，4，3： | 0 |
| 17 | Indoor Air Pollution and Pulmonary Function in Children显示文摘Pulmonary function in winter time in 1,343 school children aged 10-13 years was measured in four cities locatd in northern and southern part of China.The results showed that FVC,FEV1,PEF,V75,V50and V25 in children living in homes with coal stoves were decreased by 1.5-10.7% compared with children linving in homes with gas or LPG stoves in Chengde and Shanghai.In contrast to this,no significant difference in pulmonary function was found in Shenyang and Wuhan,It suggested that this phenomenon was related to indoor air pollution,and partly related to passive smoking or outdoor air pollution. | SHEN SHANKANG, QIN YUHUI, CAO ZHAOJING, SHANG JIANYING, LIUYUNGQING, YANG XU, DENG YONGQING, HUANG JIANG, FUZHENYING, AND SONG XIANGDONGInstitute of Prevention and Treatment for Occupational Disease, Hubei Institute ofEnvironmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing Chengde Municipal Sanitation and Anti-epidemic Station, Hebei ShenyangMunicipal Sanitation and Anti-epidemic Station, Liaoning ' WuhanMunicipal Sanitation and Anti-epidemic Station, Hubei ShanghaiMunicipal Sanitation and Anti-epidemic Station, Shanghai, China | 1992 | Biomedical and Environmental Sciences1992，5，2： | 0 |
| 18 | Advances in extracellular vesicle functionalization strategies for tissue regeneration显示文摘Extracellular vesicles(EVs)are nano-scale vesicles derived by cell secretion with unique advantages such as promoting cell proliferation,anti-inflammation,promoting blood vessels and regulating cell differentiation,which benefit their wide applications in regenerative medicine.However,the in vivo therapeutic effect of EVs still greatly restricted by several obstacles,including the off-targetability,rapid blood clearance,and undesired release.To address these issues,biomedical engineering techniques are vastly explored.This review summarizes different strategies to enhance EV functions from the perspective of drug loading,modification,and combination of biomaterials,and emphatically introduces the latest developments of functionalized EV-loaded biomaterials in different diseases,including cardio-vascular system diseases,osteochondral disorders,wound healing,nerve injuries.Challenges and future directions of EVs are also discussed. | Dandan Zheng Huitong Ruan Wei Chen Yuhui Zhang Wenguo Cui Hao Chen Hongxing Shen | 2023 | Bioactive Materials2023，，7： | 0 |
| 19 | The Effect of Elution Volume for Immunoprecipitation on m6A-Seq Analysis显示文摘Objective:To develop a cost-effective method to reduce the time consumption of elution in immunoprecipitation.Methods Two volumes(125μL for Group C and 100μL for Group T)of elution buffer were used to explore whether smaller volume could save testing time.Result:Time consumption of elution in Group T was significantly shorter than that in Group C,while the efficiency of eluted m6A-containing fragments and the performance of m^(6)A-Seq as indicated by m6A peak distributions showed no difference between the two groups.Conclusion:A smaller volume of elution buffer was an economical way to reduce time consumption in immunoprecipitation. | Yuhui Xu Lize Shen Guolin Li | 2021 | Proceedings of Anticancer Research2021，5，4： | 0 |
| 20 | Identification of Target Ligands of CORYNE in Arabidopsis by Phage Display Library显示文摘CORYNE (CRN ) 在干细胞分割和区别起重要作用在 Arabidopsis thaliana 射击顶端的分裂组织(SAM ) 。CRN 的细胞质的 kinase 领域在 Escherichia 被克隆并且表示,并且进一步由亲密关系层析的二连续的步净化了 coli。由把这净化的 CRN 用作 ligand, 12-mer 随机肽的图书馆被用来与 recombinant CRN 分子决定特定的氨基酸序列绑定。在四轮 biopanning 以后,积极噬菌体克隆被孤立并且定序,并且进一步为他们的有约束力的能力和特性由酶测试了连接 immunosorbent 试金。明确地绑在 CRN 的细胞内部的蛋白质 kinase 领域的二积极克隆被识别了。这些肽和联系 kinase 的蛋白质磷酸酶(KAPP ) 的排列显示出高类似,显示 KAPP 可能与 CRN 的细胞质的 kinase 域交往并且否定地调整 CLV 信号。我们的当前的学习将是有用的更好理解 CLV3 信号小径。 | Heng Zhao Shuzhen Li Jiping Sheng Lin Shen Yuhui Yang Bin Yao | 2011 | Journal of Integrative Plant Biology2011，53，4： | 0 |
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