|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells显示文摘人的导致的 pluripotent 茎(iPS ) 房间类似于胚胎的茎(ES ) 房间,和罐头强烈地增殖并且区分进许多房间类型。然而,人的 iPS 房间的肝的区别还没被报导了。在这份报告,人的 iPS 房间被导致由一个逐步的协议区分进肝的房间。肝房间标记的表达式和人的 iPS 的肝相关的函数导出房间的房间被监视并且与区分的人的 ES 房间和主要人的 hepatocytes 的相比。在白天 7 点的约 60% 区分的人的 iPS 房间表示了肝的标记 alpha fetoprotein 和白长袍的。在白天 21 点的区分的房间包括白朊 Asecretion,肝糖合成,脲生产和可诱导的细胞色素 P450 活动展出了肝房间功能。肝的标记的表示和 iPS 的肝相关的功能导出房间的肝的房间比得上人的 ES 导出房间的肝的房间的。这些结果证明人的 iPS 房间,类似于人的 ES 房间,能高效地被导致区分房间进象 hepatocyte 一样。 | Zhihua Song Jun Cai Yanxia Liu Dongxin Zhao Jun Yong Shuguang Duo Xijun Song Yushan Guo Yang Zhao Han Qin Xiaolei Yin Chen Wu Jie Che Shichun Lu Mingxiao Ding Hongkui Deng | 2009 | Cell Research2009，19，11： | 63 |
| 2 | Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease显示文摘 | Pingping Song Shanshan Li Hao Wu Ruize Gao Guanhua Rao Dongmei Wang Ziheng Chen Biao Ma Hongxia Wang Nan Sui Haiteng Deng Zhuohua Zhang Tieshan Tang Zheng Tan Zehan Han Tieyuan Lu Yushan Zhu Quan Chen | 2016 | Protein & Cell2016，7，2： | 8 |
| 3 | A Model for the Determination of Semi-Circular Spot Corrosion Damage and Residual Strength in Oil Pipes显示文摘Pitting corrosion often occurs due to the presence of various corrosive substances,such as CO_(2) and H_(2)S,in the pipe service environment.As a result of this process,the residual strength of oil pipes is reduced and this can compromise the integrity of the entire pipe string.In the present work,a model is introduced on the basis of the API579 standard to determine the so-called stress concentration coefficient.The model accounts for pitting corrosion shapes such as shallow semi-circles,semi-circles,and deep semi-circles.The relationship between the corrosion pit depth and opening diameter and the residual strength of the oil casing is obtained.The results show that the influence of the pit opening diameter on the stress concentration coefficient is smaller than that of the pit depth.For a constant pit opening diameter,the coefficient increases gradually with increasing the pit depth.The compressive strength and internal pressure strength of the carbon steel oil casing decrease accordingly.When the depth of the corrosion pit is relatively small,the growth of the coefficient is slower;when the depth of the corrosion pit increases to a certain value,the increase in stress concentration coefficient becomes obvious. | Hongtao Liu Maoxian Xiong Bo Zhang Junfeng Xie Jinrui Deng MifengZhao Ruijing Jiang Yushan Zheng | 2023 | Fluid Dynamics & Materials Processing2023，19，6： | 0 |
| 4 | A Captivating Stroll through an Epic Era显示文摘A good book pulls you in.Whether i ction or non-i ction,it can conjure up another world and draw you into it.You smile and you grieve;you marvel and you sigh.Only when you i nish the last line on the last page is the spell broken–yet some of the scenes stick with you. | DENG YUSHAN | 2014 | China Today2014，63，3： | 0 |
| 5 | Study on Callus Induction and Tissue Culture Regeneration System of Malus toringoides显示文摘[Objectives]To study the culture of callus produced by the leaves of the ethnic medicine‘E Se’,the induction of adventitious buds and the regeneration system of tissue culture seedlings.[Methods]Multi-factor orthogonal experiment was used to design and analyze.[Results]The best medium for callus induction was MS+2.0 mg/L 6-BA+0.1 mg/L 2,4-D.By comparing the effects of cytokinin 6-BA,KT and TDZ on induction of adventitious bud differentiation,it was found that the optimum medium for adventitious bud regeneration was MS+0.5 mg/L 6-BA+0.5 mg/L KT+0.15 mg/L IBA.Finally,adding 0.2 mg/L IBA(0.1 or 0.2 mg/L)to MS medium could effectively make regenerated seedlings produce roots,and the efficiency was more than 70%.[Conclusions]It laid a foundation for the large-scale cultivation of the seedlings of the ethnic medicine‘E Se’and the promotion of their artificial cultivation. | Xiaobo QIN Bei NIU Lijuan FAN Guozhen ZHANG Dongmei HU Bingbing ZHANG Xiaodong SHI Xinyi XU Peng WU Tingwei DAI Siying QIN Xiao LI Yushan DENG Fei ZU | 2019 | Medicinal Plant2019，10，5： | 0 |
| 6 | Circular patterns of calcium oxalate crystals induced by defective Langmuir-Blodgett film显示文摘The injury of the renal epithelial cell membrane can promote the nucleation of nascent crystals, as well as adhesion of crystals on it. It thus accelerates the formation of renal calculi. In this paper, the defective Langmuir-Blodgett (LB) films were used as a model system to simulate the injured renal epithelial cell membrane. The microcosmic structure of the defective LB film and the molecular mechanism of the effect of this film on nucleation, growth, deposited patterns and adhesion of calcium oxalate monohydrate (COM) were investigated. The circular defective domains were formed in dipalmitoylphosphatidylcholine (DPPC) LB film after the film was treated by potassium oxalate. These domains could induce ring-shaped patterns of COM crystals. In comparison, the LB film without pretreatment by potassium oxalate only induced random growth of hexagonal COM crystals. As the crystallization time increased, the size of COM crystals in the patterns increased, the crystal patterns changed from empty circles to solid circles, and the number of the circular patterns with small size (5-20 μm) increased. The results would shed light on the molecular mechanism of urolithiasis induced by injury of the renal epithelial membrane at the molecular and supramolecular level. | DENG SuiPing OUYANG JianMing XIE YuShan XING FeiYue | 2008 | Science China Chemistry2008，51，1： | 0 |
| 7 | Disturbance observer based finite-time coordinated attitude tracking control for spacecraft on SO(3)显示文摘To solve the problem of attitude synchronization control for spacecraft formation flying(SFF)suffering from external disturbances under a directed communication topology,a sliding mode disturbance observer(SMDO)based on the finite-time control strategy is developed to observe the time-varying external disturbance via estimating the upper bound of its first derivative.Meanwhile,the rotation matrix is employed to describe the attitude of SFF for the purpose of the avoidance of singularity and unwinding phenomenon.As for the attitude synchronization and the tracking control architecture,a sliding mode surface(SMS)is given such that the control objective can be achieved.The effectiveness and the validity of the proposed method are elaborated via theoretical analysis and numerical simulations. | SHI Zhen XIE Yaen DENG Chengchen ZHAO Kun HE Yushan HAO Yong | 2020 | Journal of Systems Engineering and Electronics2020，31，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员