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| 1 | 美国山核桃在云南的引种研究进展及发展前景显示文摘总结了云南53a来对美国山核桃引种、选种、生物学特性、生态适应性、苗木繁殖、丰产栽培、虫害防治的研究进展和示范推广情况。认为美国山核桃市场潜力大,在云南栽培效益高、适栽区域广、符合该省经济林树种结构调整需要,将来定会得到大力推广发展。 | 习学良 XI XUE LIANG 范志远 FAN ZHI YUAN 董润泉 DONG RUN QUAN 张雨 ZHANG YU | 2001 | 江西林业科技2001，，6： | 25 |
| 2 | Trends of Extreme Precipitation in Eastern China and Their Possible Causes显示文摘Significant increases of heavy precipitation and decreases of light precipitation have been reported over widespread regions of the globe. Global warming and effects of anthropogenic aerosols have both been proposed as possible causes of these changes. We examine data from urban and rural meteorological stations in eastern China(1955–2011) and compare them with Global Precipitation Climatology Project(GPCP) data(1979–2007) and reanalysis data in various latitude zones to study changes in precipitation extremes. Significant decreases in light precipitation and increases in heavy precipitation are found at both rural and urban stations, as well as low latitudes over the ocean, while total precipitation shows little change.Characteristics of these changes and changes in the equatorial zone and other latitudes suggest that global warming rather than aerosol effects is the primary cause of the changes. In eastern China, increases of annual total dry days(28 days) and 10 consecutive dry days(36%) are due to the decrease in light precipitation days, thereby establishing a causal link among global warming, changes in precipitation extremes, and higher meteorological risk of floods and droughts. Further, results derived from the GPCP data and reanalysis data suggest that the causal link exists over widespread regions of the globe. | LIU Run LIU Shaw Chen Ralph J.CICERONE SHIU Chein-Jung LI Jun WANG Jingli ZHANG Yuanhang | 2015 | Advances in Atmospheric Sciences2015，32，8： | 19 |
| 3 | Template-free large-scale synthesis of g-C3N4 microtubes for enhanced visible light-driven photocatalytic H2 production显示文摘 | Chao Zhou Run Shi Lu Shang Li-Zhu Wu Chen-Ho Tung Tierui Zhang | 2018 | Nano Research2018，11，6： | 17 |
| 4 | Supramolecular precursor strategy for the synthesis of holey graphitic carbon nitride nanotubes with enhanced photocatalytic hydrogen evolution performance显示文摘A simple one-step thermal polymerization method was developed for synthesis of holey graphitic carbon nitride nanotubes,involving direci eating of mixtures of melamine and urea or melamine and cyanuric acid in specific mass ratios.Supramolecular structures formed betweer the precursor molecules guided nanotube formation.The porous and nanotubular structure of the nanotubes facilitated efficient charge carrier nigration and separation,thereby enhancing photocatalytic Hz production in 20 vol.%lactic acid under visible light irradiation.Nanotubes synthesized using melamine and urea in a 1:10 mass ratio(denoted herein as CN-MU nanotubes)exhibited a photocatalytic hydroger production rate of 1,073.6μmol·h^-1·^-g with Pt as the cocatalyst,a rate of 4.7 and 3.1 times higher than traditional Pt/g-CN4 photocatalysts prepared from graphitic carbon nitride(g-CN4)obtained by direct thermal polymerization of melamine or urea,respectively.On the basis of their outstanding performance for photocatalytic H2 production,it is envisaged that the holey g-C3N4 nanotubes will find widespread uptake in other areas,including photocatalytic CO2 reduction,dye-sensitized solar cells and photoelectrochemical sensors. | Xiaoshuai Wang Chao Zhou Run Shi Qinqin Liu Geoffrey I. N. Waterhouse Lizhu Wu Chen-Ho Tung Tierui Zhang | 2019 | Nano Research2019，12，9： | 15 |
| 5 | Improved outcomes from transradial over transfemoral access in primary percutaneous coronary intervention for patients with acute ST-segment elevation myocardial infarction and upstream use of tirofiban显示文摘 | ZHANG Qi QIU Jian-ping ZHANG Rui-yan HU Jian YANG Zhen-kun DING Feng-hua DU Run ZHU Tian-qi ZHANG Jian-sheng SHEN Wei-feng | 2013 | Chinese Medical Journal2013，，6： | 14 |
| 6 | RAB31 marks and controls an ESCRT-independent exosome pathway显示文摘Exosomes are generated within the multivesicular endosomes(MVEs)as intraluminal vesicles(ILVs)and secreted during the fusion of MVEs with the cell membrane.The mechanisms of exosome biogenesis remain poorly explored.Here we identify that RAB31 marks and controls an ESCRT-independent exosome pathway.Active RAB31,phosphorylated by epidermal growth factor receptor(EGFR),engages flotillin proteins in lipid raft microdomains to drive EGFR entry into MVEs to form ILVs,which is independent of the ESCRT(endosomal sorting complex required for transport)machinery.Active RAB31 interacts with the SPFH domain and drives ILV formation via the Flotillin domain of flotillin proteins.Meanwhile,RAB31 recruits GTPase-activating protein TBC1D2B to inactivate RAB7,thereby preventing the fusion of MVEs with lysosomes and enabling the secretion of ILVs as exosomes.These findings establish that RAB31 has dual functions in the biogenesis of exosomes:driving ILVs formation and suppressing MVEs degradation,providing an exquisite framework to better understand exosome biogenesis. | Denghui Wei Weixiang Zhan Ying Gao Liyan Huang Run Gong Wen Wang Ruhua Zhang Yuanzhong Wu Song Gao Tiebang Kang | 2021 | Cell Research2021，31，2： | 12 |
| 7 | Computed morphometric analysis and expression of alpha fetoprotein in hepatocellular carcinoma and its related lesion显示文摘INTRODUCTION Hepatocellular carcinoma(HCC)is closely relatedwith hepatitis and cirrhosis.In order to investigatethe pathogenesis and early pathologic diagnosis ofHCC,HCC and related lesions were analyzedqualitively and quantitively by automatic imageanalysor and immunohistochemical assay. | Li Juan Shen Zong Ji Zhang Yang Ming Ou Hua Xian Zhang Run Huang Yun He Min Jie Wang Guo Shu Xu | 2000 | World Journal of Gastroenterology2000，6，3： | 11 |
| 8 | Multiple cytokine profiling in serum for early detection of gastric cancer显示文摘AIM To investigate the value of multiparameter joint analysis in the early diagnosis of gastric cancer(GC) in clinical practice.METHODS Concentrations of CEA, CA724 and three kinds of cytokines(TNF-α, IL-6 and IL-8) in 176 GC patients, 117 atypical hyperplasia patients, and 204 healthy control individuals were used for building the diagnostic model, then 58 GC patients, 41 atypical hyperplasia patients, and 66 healthy control individuals were enrolled independently. The joints of the indicators were analyzed by binary logistic regression analysis method.RESULTS For discriminating the healthy control group and the GC group, IL-6 had the best diagnostic value, and the area under curve(AUC) of joint analysis was 0.95(0.93-0.97). For the early stage and advanced stage GC, the AUC were 0.95(0.92-0.98) and 0.95(0.92-0.97). For discriminating the atypical hyperplasia group and GC group, CA724 had the best diagnostic value, and the AUC of joint analysis was 0.97(0.95-0.99). For the early stage and advanced stage GC groups, the AUC were 0.98(0.96-0.99) and 0.96(0.94-0.98). After evaluation, for discriminating the GC, early stage GC and advanced cancer group from the healthy control group, the diagnostic sensitivity was 89.66%, 84.21% and 92.31%, respectively, and the specificity was 92.42%, 90.91% and 90.91%. For discriminating the GC, early stage GC and advanced cancer groups from the atypical hyperplasia group, the diagnostic sensitivity was 87.93%, 78.95% and 92.31%, respectively, and the specificity was 87.80%, 85.37% and 90.24%.CONCLUSION We have built a diagnostic model including CEA, CA724, IL-6, IL-8, and TNF-α. It may provide potential assistance as a screening method for the early detection of GC. | Jian Li Liang Xu Zeng-Ci Run Wen Feng Wen Liu Peng-Jun Zhang Zhi Li | 2018 | World Journal of Gastroenterology2018，24，21： | 11 |
| 9 | Structure Design of Lower Limb Exoskeletons for Gait Training显示文摘Due to the close physical interaction between human and machine in process of gait training, lower limb exoskeletons should be safe, comfortable and able to smoothly transfer desired driving force/moments to the patients. Correlatively, in kinematics the exoskeletons are required to be compatible with human lower limbs and thereby to avoid the uncontrollable interactional loads at the human-machine interfaces. Such requirement makes the structure design of exoskeletons very difficult because the human-machine closed chains are complicated. In addition, both the axis misalignments and the kinematic character difference between the exoskeleton and human joints should be taken into account. By analyzing the DOF(degree of freedom) of the whole human-machine closed chain, the human-machine kinematic incompatibility of lower limb exoskeletons is studied. An effective method for the structure design of lower limb exoskeletons, which are kinematically compatible with human lower limb, is proposed. Applying this method, the structure synthesis of the lower limb exoskeletons containing only one-DOF revolute and prismatic joints is investigated; the feasible basic structures of exoskeletons are developed and classified into three different categories. With the consideration of quasi-anthropopathic feature, structural simplicity and wearable comfort of lower limb exoskeletons, a joint replacement and structure comparison based approach to select the ideal structures of lower limb exoskeletons is proposed, by which three optimal exoskeleton structures are obtained. This paper indicates that the human-machine closed chain formed by the exoskeleton and human lower limb should be an even-constrained kinematic system in order to avoid the uncontrollable human-machine interactional loads. The presented method for the structure design of lower limb exoskeletons is universal and simple, and hence can be applied to other kinds of wearable exoskeletons. | LI Jianfeng ZHANG Ziqiang TAO Chunjing JI Run | 2015 | Chinese Journal of Mechanical Engineering2015，28，5： | 11 |
| 10 | Micro-trichome as a class I homeodomain-leucine zipper gene regulates multicellular trichome development in Cucumis sativus显示文摘Plant trichomes serve as a highly suitable model for investigating cell differentiation at the single-cell level.The regulatory genes involved in unicellular trichome development in Arabidopsis thaliana have been intensively studied,but genes regulating multicellular trichome development in plants remain unclear.Here,we characterized Cucumis sativus(cucumber) trichomes as representative multicellular and unbranched structures,and identified Micro-trichome(Mict),using map-based cloning in an F_2 segregating population of7,936 individuals generated from a spontaneous mict mutant.In mict plants,trichomes in both leaves and fruits,are small,poorly developed,and denser than in the wild type.Sequence analysis revealed that a 2,649-bp genomic deletion,spanning the first and second exons,occurred in a plant-specific class I homeodomain-leucine zipper gene.Tissue-specific expression analysis indicated that Mict is strongly expressed in the trichome cells.Transcriptome profiling identified potential targets of Mict including putative homologs of genes known in other systems to regulate trichome development,meristem determinacy,and hormone responsiveness.Phylogenic analysis charted the relationships among putative homologs in angiosperms.Our paper represents initial steps toward understanding the development of multicellular trichomes. | Jun-Long Zhao Jun-Song Pan Yuan Guan Wei-Wei Zhang Bei-Bei Bie Yun-Li Wang Huan-Le He Hong-Li Lian Run Cai | 2015 | Journal of Integrative Plant Biology2015，57，11： | 9 |
| 11 | Penile rehabilitation with a vacuum erectile device in an animal model is related to an antihypoxic mechanism: blood gas evidence显示文摘我们的以前的学习显示出可勃起的设备(VED ) 治疗改进了的那真空在有双边的多孔的神经压碎(BCNC ) 的老鼠的可勃起的功能损害。这研究被设计由分析多孔的氧浸透在阴茎康复探索 VED 的机制(那么 2) 并且在在 BCNC 以后阻止阴茎收缩上检验 VED 治疗的效果。三十只成年 Sprague-Dawley 老鼠随机被分配进三个组:组织 1,假冒的外科;组织 2, BCNC;并且组织 3, BCNC+ VED。阴茎长度和直径在一个每周的基础上被测量。在 4 星期治疗以后,阴茎血被三个方法为血气体分析(BGA ) 提取:方法 1,多孔的血以松驰的状态被把发成送气音;方法 2,多孔的血以拖拉状态被把发成送气音;并且方法 3,多孔的血在使用 VED 以后立即被把发成送气音。2 价值被血气体分析器因此测试。结果证明那 VED 治疗在阻止 BCNC 导致的阴茎收缩是有效的(阴茎弄短:BCNC 组 1.9 ± 1.1 公里;VED 组 0.3 ± 1.0 公里;P< 0.01。阴茎直径减小:BCNC 组 0.28 ± 0.14 公里;VED 组 0.04 ± 0.14 公里;P< 0.01 ) 。2±s.d. 因此珍视的平均数被 VED 申请增加(88.25 % ± 4.94 %) 与相比松驰(76.53 % ± 4.16 %) 或拖拉组(78.93 % ± 2.56 %)(P< 0.05 ) 。在在 VED 申请以后的阴茎海绵体权利的计算的血构造是 62 %动脉并且 38 %静脉的血。这些调查结果建议那 VED 治疗能有效地与 BCNC 损害在老鼠保存阴茎尺寸。VED 治疗的有益的效果与由那么增加多孔的血的 antihypoxia 有关是 2 。 | Hao-Cheng Lin Wen-Li Yang Jun-Lan Zhang Yu-Tian Dai Run Wang | 2013 | Asian Journal of Andrology2013，15，3： | 9 |
| 12 | Two gap-free reference genomes and a global view of the centromere architecture in rice显示文摘Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ago.However,reference genomes for all higher organisms to date contain gaps and missing sequences.Here,we report the assembly and analysis of gap-free reference genome sequences for two elite O.sativa xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and yield.Gap-free reference genomes provide the opportunity for a global view of the structure and function of centromeres.We show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and structures.In addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and homogenization.Both genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively transcribed.Two large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two genomes.The availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties. | Jia-Ming Song Wen-Zhao Xie Shuo Wang Yi-Xiong Guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng Huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou Xi-Tong Zhu Daojun Yuan Joshua Udall Weibo Xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang Ling-Ling Chen | 2021 | Molecular Plant2021，14，10： | 9 |
| 13 | Nanoparticle-immersed paper imprinting mass spectrometry imaging reveals uptake and translocation mechanism of pesticides in plants显示文摘Design and discovery of carrier-mediated modified pesticides are vital for reducing pesticide dosage and increasing utilization,yet it remains a great challenge due to limited insights into plant translocation mechanisms.Nanostructure/nanoparticle assisted laser desorption/ionization strategy has established itself as a preferential analytical tool for biological tissue analysis,whereas potential applications in plant sciences are hindered with regard to the inability to slice plant leaves and petals.Herein,we report gold nanoparticle(AuNP)-immersed paper imprinting mass spectrometry imaging(MSI)for the spatiotemporal visualization of pesticide translocation in plant leaves.This approach plays a dual role in preserving spatial information and improving ionization efficiency for pesticides regardless of imaging artifacts due to homogenous AuNP deposition.Using this MSI platform,we proposed the elaborate plant translocation mechanism of agrochemicals for the first time,which is currently poorly understood.The dynamic processes of carrier-mediated pesticides can be clearly visualized,including crossing of plasma membranes by transporters,translocation downward in stems through the phloem,diffusion to the xylem and,conversely,accumulation at margins of the treated leaves.Moreover,this AuNP-assisted paper imprinting method could be highly compatible with laser-based MSI instruments,expediting researches across a broad range of fields,especially in nanomaterial development and life sciences. | Xinzhou Wu Run Qin Hanxiang Wu Guangkai Yao Yue Zhang Ping Li Yizhu Xu Zhixiang Zhang Zhibin Yin Hanhong Xu | 2020 | Nano Research2020，13，3： | 8 |
| 14 | Biochemical sensing in graphene-enhanced microfiber resonators with individual molecule sensitivity and selectivity显示文摘Photonic sensors that are able to detect and track biochemical molecules offer powerful tools for information acquisition in applications ranging from environmental analysis to medical diagnosis.The ultimate aim of biochemical sensing is to achieve both quantitative sensitivity and selectivity.As atomically thick films with remarkable optoelectronic tunability,graphene and its derived materials have shown unique potential as a chemically tunable platform for sensing,thus enabling significant performance enhancement,versatile functionalization and flexible device integration.Here,we demonstrate a partially reduced graphene oxide(prGO)inner-coated and fiber-calibrated Fabry-Perot dye resonator for biochemical detection.Versatile functionalization in the prGO film enables the intracavity fluorescent resonance energy transfer(FRET)to be chemically selective in the visible band.Moreover,by measuring the intermode interference via noise canceled beat notes and locked-in heterodyne detection with Hz-level precision,we achieved individual molecule sensitivity for dopamine,nicotine and single-strand DNA detection.This work combines atomic-layer nanoscience and high-resolution optoelectronics,providing a way toward high-performance biochemical sensors and systems. | Zhongxu Cao Baicheng Yao Chenye Qin Run Yang Yanhong Guo Yufeng Zhang Yu Wu Lei Bi Yuanfu Chen Zhenda Xie Gangding Peng Shu-Wei Huang Chee Wei Wong Yunjiang Rao | 2019 | Light(Science & Applications)2019，8，1： | 8 |
| 15 | Impact of angina prior to acute ST-elevation myocardial infarction on short-term outcomes after primary percutaneous coronary intervention: results from the Shanghai Registry of Acute Coronary Syndrome (SRACE)显示文摘 | ZHANG Qi ZHANG Rui-yan ZHU Tian-qi HU Jian YANG Zhen-kun DING Feng-hua DU Run ZHU Zheng-bin SHEN Wei-feng | 2012 | Chinese Medical Journal2012，，6： | 7 |
| 16 | An observation-based perspective of winter haze days in four major polluted regions of China显示文摘An observation-based approach is used to examine key characteristics of winter haze days in four major polluted regions in China.Major findings in this study are:first,there was no significant trend in the number of winter haze days in most provinces and districts in eastern China from 1973 to 2012,contrary to the 2.5-fold increase in the emissions of particulate matter and its precursors(PM emissions)in the same period of time.Second,meteorological and climate conditions rather than PM emissions are in control of the interannual variabilities and trends of winter haze days.These interannual variabilities(ranging from 24 to 125%)pose a substantial masking effect that must be overcome by any control of PM emissions before its impact becomes statistically detectable.Finally,we find that global warming may have contributed significantly to the trend of winter haze days in eastern China. | Lu Mao Run Liu Wenhui Liao Xuemei Wang Min Shao Shaw Chen Liu Yuanhang Zhang | 2019 | National Science Review2019，6，3： | 7 |
| 17 | A new neuroprotective bakkenolide from the rhizome of Petasites tricholobus显示文摘新 bakkenolide 类型混合物, bakkenolide-Va (1 ) ,从 Petasites tricholobus 的根茎被孤立。结构根据各种各样的 NMR 被描绘(1H, 13C, 1H 鈥 ? H 舒适, HMQC, HMBC 和 NOESY ) 并且集体 spectrometry 数据。bakkenolide-Va 的 neuroprotective 活动在组织缺氧葡萄糖剥夺和氧化侮辱的各种各样的类型对待的首先有教养的神经原被调查。 | Na Zhang Mei Li Guo Ge Zhang Run Ping Li | 2008 | Chinese Chemical Letters2008，19，7： | 7 |
| 18 | Review of CHINARE chemical oceanographic research in the Southern Ocean during 1984–2016显示文摘Between 1984 and 2016, China executed 33 Antarctic cruises with the icebreaker R/V Xuelong, which have provided opportunities for Chinese scientists to investigate the status and changes of the Southern Ocean. Research in chemical oceanography constitutes one of the primary missions of the Chinese National Antarctic Research Expedition(CHINARE). This paper reviews nearly 30 years of Chinese Antarctic expeditions, focusing on the major progress achieved in chemical oceanographic research. Specifically, the sea-surface distributions and air–sea fluxes of CO_2 and N_2O are considered, and the transport, flux, and budget of organic matter are investigated based on isotopes in the Southern Ocean, especially in Prydz Bay. In addition, the nutrient distribution and deep-water particle export in Prydz Bay and the study of aerosol heavy metal characteristics are considered. Finally, the prospects for future Chinese Antarctic chemical oceanographic research are outlined. | CHEN Liqi CHEN Min ZHAN Liyan QI Di GAO Zhongyong WANG Jianjun XU Suqing CHEN Kui ZENG Jian ZHANG Run | 2017 | Advances in Polar Science2017，28，2： | 6 |
| 19 | A new caffeic ester from Incarvillea mairei var.granditlora (Wehrhahn) Grierson显示文摘新 cafferic 酉旨,(+)-2-(1-hydroxyl-4-oxocyclohexyl) 乙醇 caffeate,从 Incarvillea mairei var 的整个植物的 80% 乙醇摘录被孤立。granditlora (Wehrhahn ) Grierson。混合物的结构被分光镜的方法建立。 | Yong Qing Su Wei Dong Zhang Chuan Zhang Run Hui Liu Yun Heng Shen | 2008 | Chinese Chemical Letters2008，19，7： | 6 |
| 20 | Two-dimensional Sn2Ta2O7 nanosheets as efficient visible lightdriven photocatalysts for hydrogen evolution显示文摘Two-dimensional Sn2Ta2O7 nanosheets with a thickness of^10 nm were successfully prepared through a novel tantalic acid-based solid-state reaction method at reduced temperature.The as-obtained samples were characterized by powder X-ray diffraction(XRD),ultraviolet–visible(UV–Vis)diffuse reflectance spectra,scanning electron microscopy(SEM),transmission electron microscopy(TEM)and Brunauer–Emmett–Teller(BET)analysis.The photocatalytic performance of Sn2 Ta2 O7 nanosheets was evaluated by photocatalytic water splitting for hydrogen evolution under visible light irradiation(k C 400 nm).The Sn2Ta2O7 nanosheets with a large surface area of 25.9 m^2·g^-1 showed higher H2 production activity,which was about 4.4 times higher than that of bulk Sn2 Ta2O7 in lactic acid aqueous solutions using Pt as a cocatalyst.The improved photocatalytic performance mainly benefited from the nanosheet structure,which provided abundant surface active sites and facilitated the photogenerated charge carrier separation efficiently.This workmay open up new opportunity to develop novel nanostructured tantalum-based semiconductors with improved catalytic performance for solar energy conversion. | Xiao-Shuai Wang Chao Zhou Run Shi Qin-Qin Liu Tie-Rui Zhang | 2019 | Rare Metals2019，38，5： | 6 |
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