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| 1 | Environmental connections of novel avian-origin H7N9 influenza virus infection and virus adaptation to the human显示文摘A novel H7N9 influenza A virus has been discovered as the causative identity of the emerging acute respiratory infection cases in Shanghai,China.This virus has also been identified in cases of infection in the neighboring area Hangzhou City in Zhejiang Province.In this study,epidemiologic,clinical,and virological data from three patients in Hangzhou who were confirmed to be infected by the novel H7N9 influenza A virus were collected and analyzed.Human respiratory specimens and chicken feces from a contacted free market were tested for influenza virus by real-time reverse transcription PCR(RT-PCR) and sequencing.The clinical features of the three cases were similar featured with high fever and severe respiratory symptoms;however,only one of the patients died.A certain degree of diversity was observed among the three Hangzhou viruses sequenced from human samples compared with other reported H7N9 influenza A viruses.The sequences of the novel avian-origin H7N9 influenza viruses from Hangzhou City contained important amino acid substitutions related to human adaptation.One of the Hangzhou viruses had gained a novel amino acid substitution(Q226I) in the receptor binding region of hemagglutinin.More importantly,the virus sequenced from the chicken feces had a 627E substitution in the PB2 protein instead of the mammalian-adapted 627K substitution that was found in the PB2 proteins from the Hangzhou viruses from the three patients.Therefore,the newly-emerging H7N9 virus might be under adaptation pressure that will help it 'jump' from avian to human hosts.The significance of these substitutions needs further exploration,with both laboratory experiments and extensive field surveillance. | LI Jun YU XinFen PU XiaoYing XIE Li SUN YongXiang XIAO HaiXia WANG FenJuan DIN Hua WU Ying LIU Di ZHAO GuoQiu LIU Jun PAN JingCao | 2013 | Science China(Life Sciences)2013，56，6： | 32 |
| 2 | Radiofrequency ablation or microwave ablation combined with transcatheter arterial chemoembolization in treatment of hepatocellular carcinoma by comparing with radiofrequency ablation alone显示文摘Objective:To compare radiofrequency ablation(RFA) or microwave ablation(MWA) and transcatheter arterial chemoembolization(TACE) with RFA or MWA monotherapy in hepatocellular carcinoma(HCC).Methods:A prospective,randomized,controlled trial was conducted on 94 patients with HCC ≤7 cm at a single tertiary referral center from June 2008 to June 2010 at the Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Southeast University.The patients were randomly assigned into the TACERFA or TACE-MWA(combined treatment group) and the RFA-alone or MWA-alone groups(control group).The primary end point was overall survival.The secondary end point was recurrence-free survival,and the tertiary end point was adverse effects.Results:Until the time of censor,17 patients in the TACE-RFA or TACE-MWA group had died.The median follow-up time of the patients who were still alive for the TACE-RFA or TACE-MWA group was 47.5±11.3 months(range,29 to 62 months).The 1-,3- and 5-year overall survival for the TACE-RFA or TACE-MWA group was 93.6%,68.1% and 61.7%,respectively.Twenty-five patients in the RFA or MWA group had died.The median follow-up time of the patients who were still alive for the RFA or MWA group was 47.0±12.9 months(range,28 to 62 months).The 1-,3- and 5-year overall survival for the RFA or MWA group was 85.1%,59.6% and 44.7%,respectively.The patients in the TACE-RFA or TACE-MWA group had better overall survival than the RFA or MWA group [hazard ratio(HR),0.526;95% confidence interval(95% CI),0.334-0.823;P=0.002],and showed better recurrence-free survival than the RFA or MWA group(HR,0.582;95% CI,0.368-0.895;P=0.008).Conclusions:RFA or MWA combined with TACE in the treatment of HCC ≤7 cm was superior to RFA or MWA alone in improving survival by reducing arterial and portal blood flow due to TACE with iodized oil before RFA. | Yongxiang Yi Yufeng Zhang Qiang Wei Liang Zhao Jianbo Han Yan Song Ying Ding Guilan Lu Junmao Liu Huaiying Ding Feng Dai Xiaojun Tang | 2014 | Chinese Journal of Cancer Research2014，26，1： | 29 |
| 3 | Long range trans-Pacific transport and deposition of Asian dust aerosols显示文摘在他们的横渡太平洋期间,运输可能引起重要海洋的浮游植物生物资源的亚洲灰尘喷雾器的免职增加。然而,横渡太平洋灰尘运输,免职,和空间分发的知识由于在亚洲次洲,北方太平洋,和北美洲的连续、同时的观察的缺乏仍然是差的。灰尘在 2001 年 4 月 6 日期间袭击的严格的亚洲人提供了一个机会获得横渡太平洋灰尘运输和免职的更好的理解,用从卫星的观察的一个全面集合,基于地面的轻察觉并且变化,飞机,和表面观察网络。观察和模型模拟构画出灰尘运输,免职,垂直侧面,和空间分发的一般模式。下列点被遵守:(1 ) 表面灰尘集中沿着运输小径从 80 ° E 与增加的灰尘运输距离指数地减少了到 120 ° W;(2 ) 灰尘集中山峰的高度与在北方太平洋区域增加运输距离增加了;并且(3 ) 灰尘免职的空间分发主要取决于横渡太平洋运输线路。 | HAN Yongxiang FANG Xiaomin ZHAO Tianliang KANG Shichang | 2008 | Journal of Environmental Sciences2008，20，4： | 14 |
| 4 | Effects of Shuanghuanglian oral liquids on patients with COVID-19:a randomized,open-label,parallel-controlled,multicenter clinical trial显示文摘We conducted a randomized,open-label,parallel-controlled,multicenter trial on the use of Shuanghuanglian(SHL),a traditional Chinese patent medicine,in treating cases of COVID-19.A total of 176 patients received SHL by three doses(56 in low dose,61 in middle dose,and 59 in high dose)in addition to standard care.The control group was composed of 59 patients who received standard therapy alone.Treatment with SHL was not associated with a difference from standard care in the time to disease recovery.Patients with 14-day SHL treatment had significantly higher rate in negative conversion of SARS-CoV-2 in nucleic acid swab tests than the patients from the control group(93.4%vs.73.9%,P=0.006).Analysis of chest computed tomography images showed that treatment with high-dose SHL significantly promoted absorption of inflammatory focus of pneumonia,which was evaluated by density reduction of inflammatory focus from baseline,at day 7(mean difference(95%CI),−46.39(−86.83 to−5.94)HU;P=0.025)and day 14(mean difference(95%CI),−74.21(−133.35 to−15.08)HU;P=0.014).No serious adverse events occurred in the SHL groups.This study illustrated that SHL in combination with standard care was safe and partially effective for the treatment of COVID-19. | Li Ni Zheng Wen Xiaowen Hu Wei Tang Haisheng Wang Ling Zhou Lujin Wu Hong Wang Chang Xu Xizhen Xu Zhichao Xiao Zongzhe Li Chene Li Yujian Liu Jialin Duan Chen Chen Dan Li Runhua Zhang Jinliang Li Yongxiang Yi Wei Huang Yanyan Chen Jianping Zhao Jianping Zuo Jianping Weng Hualiang Jiang Dao Wen Wang | 2021 | Frontiers of Medicine2021，15，5： | 7 |
| 5 | Comparative Studies of Non-noble Metal Modified Mesoporous M-Ni-CaO-ZrO2 (M=Fe, Co, Cu) Catalysts for Simulated Biogas Dry Reforming显示文摘现在的工作被瞄准由增加第二非高贵的金属的干燥改过为 biogas 改进基于 Ni 的催化剂的表演(Fe,公司, Cu ) 进以前学习的 mesoporous Ni-CaO-ZrO 2 nanocomposite。Biogas 为干燥改过反应与相等的甲烷和二氧化碳被模仿。X光检查衍射( XRD ),X光检查光电子光谱学( XPS ), N 2吸附,规划温度的减小( TPR ), thermogravimetric 分析( TGA ),并且传播电子显微镜学( TEM )大小被拿描绘二金属的催化剂以及积累的碳免职的结构、文本的性质。Fe 的增加导致订 Fe-Ni-CaO-ZrO 2 样品的 mesopores 的生长的更少,并且 Cu 的存在在 Cu-Ni-CaO-ZrO 2 导致免费 NiO 的相对更大的部分。与 Fe 和 Cu 相比,公司的存在能高效地形成有益的双金属效果并且提高在 biogas 的催化剂的活动和稳定性弄干改革反应的在因此提高的 Ni 和 CaO-ZrO 2, 之间的强壮的金属支持相互作用。 | Changzhen Wang Yin Zhang Yongzhao Wang Yongxiang Zhao | 2017 | Chinese Journal of Chemistry2017，35，1： | 5 |
| 6 | RESEARCH PROGRESS ON STRUCTURAL FATIGUE RELIABILITY DESIGN AND ANALYSIS METHODS OF CHINESE RAILWAY VEHICLES显示文摘state-of-art 评论在疲劳可靠性设计和中国铁路车辆的结构的分析方法上被给新进展。首先,结构服从于强调历史和这历史的复杂随机的疲劳应该被联合动态模拟和联机检查决定。第二,随机的疲劳体质属于内在的疲劳现象,一个概率的模型被开发很好与幸存概率和信心的二大小描述他们,类似的模型也为随机的压力生活关系被介绍并且适当地外推进长疲劳生命政体。第三,疲劳限制的概念应该在给定的疲劳生活作为疲劳力量被理解,一个所谓的本地 Basquin 模型方法为测量随机的力量被建议。Inaddition,绘画并且为不可分地描绘随机的疲劳力量的 Goodman 铁匠图的应用程序方法以十公里被建立。第四,一个基于 reliabilitystress 的方法与随机的组成的关系的考虑被构造。Thesenew 进展为铁路疲劳可靠性设计和分析形成一个新框架工作。 | ZHAO Yongxiang PENG Jiachun YANG Bing | 2007 | Chinese Journal of Mechanical Engineering2007，20，4： | 5 |
| 7 | Therapeutic siRNA:state of the art显示文摘RNA interference(RNAi)is an ancient biological mechanism used to defend against external invasion.It theoretically can silence any disease-related genes in a sequence-specific manner,making small interfering RNA(siRNA)a promising therapeutic modality.After a two-decade journey from its discovery,two approvals of siRNA therapeutics,ONPATTRO®(patisiran)and GIVLAARI™(givosiran),have been achieved by Alnylam Pharmaceuticals.Reviewing the long-term pharmaceutical history of human beings,siRNA therapy currently has set up an extraordinary milestone,as it has already changed and will continue to change the treatment and management of human diseases.It can be administered quarterly,even twice-yearly,to achieve therapeutic effects,which is not the case for small molecules and antibodies.The drug development process was extremely hard,aiming to surmount complex obstacles,such as how to efficiently and safely deliver siRNAs to desired tissues and cells and how to enhance the performance of siRNAs with respect to their activity,stability,specificity and potential off-target effects.In this review,the evolution of siRNA chemical modifications and their biomedical performance are comprehensively reviewed.All clinically explored and commercialized siRNA delivery platforms,including the GalNAc(N-acetylgalactosamine)–siRNA conjugate,and their fundamental design principles are thoroughly discussed.The latest progress in siRNA therapeutic development is also summarized.This review provides a comprehensive view and roadmap for general readers working in the field. | Bo Hu Liping Zhong Yuhua Weng Ling Peng Yuanyu Huang Yongxiang Zhao Xing-Jie Liang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 8 | Differentially weighted direct simulation Monte Carlo method for particle collision in gas-solid flows显示文摘In gas-solid flows,particle-particle interaction(typical,particle collision) is highly significant,despite the small particles fractional volume.Widely distributed polydisperse particle population is a typical characteristic during dynamic evolution of particles(e.g.,agglomeration and fragmentation) in spite of their initial monodisperse particle distribution.The conventional direct simulation Monte Carlo(DSMC)method for particle collision tracks equally weighted simulation particles,which results in high statistical noise for particle fields if there are insufficient simulation particles in less-populated regions.In this study,a new differentially weighted DSMC(DW-DSMC) method for collisions of particles with different number weight is proposed within the framework of the general Eulerian-Lagrangian models for hydrodynamics.Three schemes(mass,momentum and energy conservation) were developed to restore the numbers of simulation particle while keeping total mass,momentum or energy of the whole system unchanged respectively.A limiting case of high-inertia particle flow was numerically simulated to validate the DW-DSMC method in terms of computational precision and efficiency.The momentum conservation scheme which leads to little fluctuation around the mass and energy of the whole system performed best.Improved resolution in particle fields and dynamic behavior could be attained simultaneously using DW-DSMC,compared with the equally weighted DSMC.Meanwhile,computational cost can be largely reduced in contrast with direct numerical simulation. | Yongxiang He Haibo Zhao Haoming Wang Chuguang Zheng | 2015 | Particuology2015，13，4： | 4 |
| 9 | Mapping Microscale Strain Fields Around a Crack Tip in Molybdenum Via Geometric Phase Analysis and Digital Image Correlation显示文摘Uniaxial tension tests were conducted on single-edge-notched tensile specimens of pure molybdenum with a mesh grid pattern in front of the notch. A series of images of crack initialization and propagation with a distorted mesh grid pattern were obtained by means of in situ scanning electron microscopy. Strain fields around the crack tip were mapped successively using geometric phase analysis and digital image correlation techniques, and then compared with the predictions obtained through linear elastic fracture mechanics(LEFM). The comparison shows that the measured strain distribution ahead of the crack tip is consistent with the LEFM predictions of up to 25 μm from the crack tip. | Chunwang Zhao Wencai Li Jijun Li Yongxiang Li Quanlong Liu Lifu Wang Qingyu Hou Yongming Xing | 2018 | Acta Mechanica Solida Sinica2018，31，3： | 3 |
| 10 | Exploring the binding mechanism of thioflavin-T to the β-amyloid peptide by blind docking method显示文摘Using blind dock method,we find that thioflavin-T(ThT) can bind to both monomers and fibrils of the full-length β-amyloid peptide(Aβ1-42) and has a higher binding affinity to the fibrils.It is shown that the hydrophobic interaction between the ligand(ThT) and substrate(Aβ1-42) are stronger than hydrogen bonds.Furthermore,ThT tends to be located near the C-terminus of Aβ monomer through hydrophobic and electrostatic interactions,while it tends to contact the residues Met35 and Gly27 of the fibril surface mainly through hydrophobic interaction.Finally,according to the docking results and ThT fluorescence assay,a kinetic equation is proposed to deduce the aggregation rate coefficient of Aβ1-42. | ZHAO DeSheng CHEN YongXiang LIU Qian ZHAO YuFen LI YanMei | 2012 | Science China Chemistry2012，55，1： | 3 |
| 11 | Immune responses of dendritic cells combined with tumor-derived autophagosome vaccine on hepatocellular carcinoma显示文摘Background:To induce and collect tumor-derived autophagosomes(DRibbles) from tumor cells as an antitumor vaccine by inhibiting the functions of proteasomes and lysosomes.Methods:Dendritic cells(DCs) generated from peripheral blood mononuclear cell(PBMC) of hepatocellular carcinoma(HCC) patients were cocultured with DRibbles,and then surface molecules of DCs,as well as surface molecules on DCs,were determined by flow cytometry.Meanwhile,immune responses of the DCs-DRibbles were examined by mixed lymphocyte reactions.Results:DRibbles significantly induced the expression of CD80,CD83,CD86 and HLA-DR on DCs.The enzyme-linked immunosorbnent assay(ELISA) showed that IFN-γ levels after vaccination increased than before in most patients,but CD8+ proportion of PBMC increased only in nine patients.Higher levels of IFN-γ were detected in the CD8+ cells than CD4+ T cells.These results suggested that DCs-DRibbles vaccine could induce antigen-specific cellular immune response on HCC and could prime strong CD8+ T cell responses,supporting it as a tumor vaccine candidate.Conclusions:Our results demonstrate that HCC/DRibbles-pulsed DCs immunotherapy might be deployed as an effective antitumor vaccine for HCC immunotherapy in clinical trials. | Yongxiang Yi Jianbo Han Liang Zhao Chunying Wang Yuan Fang Qiang Wei Liang Hu Junmao Liu Yufeng Zhang Lili Wang | 2015 | Chinese Journal of Cancer Research2015，27，6： | 2 |
| 12 | Mechanical properties,thermophysical properties and electronic structure of Yb^(3+)or Ce^(4+)-doped La_(2)Zr_(2)O_(7)-based TBCs显示文摘First-principles calculations based on density functional theory were perfo rmed to investigate the cohesive energies,elastic modulus,Debye temperatures,thermal conductivities and density of states of La_(2-x)Yb_(x)Zr_(2)O_(7),La_(2)Zr_(2-x)Ce_(x)O_(7)and La_(2-x)Yb_(x)Zr_(2-x)Ce_(x)O_(7)(x=0.00,0.25,0.50,0.75,1.00)ceramics.The results show that doping Yb~(3+)or Ce~(4+)into La_(2)Zr_(2)O_(7)reduces its elastic modulus,thermal conductivity and Debye temperature.Compared with La_(2-x)Yb_(x)Zr_(2)O_(7)(x≠0.00),La_(2)Zr_(2-x)Ce_(x)O_(7)compounds have better ductility and lower Debye te mperature.The Debye temperature values of La_(2)Zr_(2-x)Ce_(x)O_(7)(x≠0.00)co mpounds are in the range of 485.0-511.5 K.Among all components,the fluorite-type La_(2-x)Yb_(x)Zr_(2-x)Ce_(x)O_(7)(x=0.75,1.00)compounds exhibit better mechanical and thermophysical properties,and their thermal conductivity values are only 1.213-1.246 W/(m·K)(1073 K),which are 14.5%-16.7%lower than that of the pure La_(2)Zr_(2)O_(7).Thus,our findings open an entirely new avenue for TBCs. | Pengsen Zhao Haizhong Zheng Guifa Li Yongxiang Geng Yixin Xiao Hongbo Guo Ping Peng | 2023 | Journal of Rare Earths2023，41，4： | 2 |
| 13 | Effects of polydopamine modification on self-grown Cu O cube anodes in lithium-ion batteries显示文摘We report the synthesis of Cu O cubes with well-defined size and shape by thermal treatments of Cu2O cubes.Polydopamine(PDA)is introduced to modify the Cu O cubes by the in-situ polymerization of the dopamine precursor.The initial specific capacity of the lithium-ion batteries using the Cu O cubes as anodes increases about 10 times at a 0.5 C rate as a result of the modification of PDA.The overall specific capacity for 100 cycles also increases effectively due to the introduction of PDA.So PDA as surface modifying agent significantly improves the electrochemical performance of the Cu O anodes. | HAO LiHua WU LiQiong JIA ZhiQi ZHAO YongXiang LI XinHeng | 2016 | Science China(Technological Sciences)2016，59，4： | 2 |
| 14 | Coupon TFRC:a mechanism being friendly to both TCP and continuous stream显示文摘 | Yongxiang Zhao Chang-jia Chen | 2001 | Journal COMPUTER NETWORKS2001，，11： | 1 |
| 15 | Boron difluoride formazanate dye for high-efficiency NIR-Ⅱ fluorescence imaging-guided cancer photothermal therapy显示文摘The small molecular second near-infrared(NIR-Ⅱ, 1000–1700 nm) dye-based nanotheranostics can concurrently combine deep-tissue photodiagnosis with in situ phototherapy, which occupies a vital position in the early detection and precise treatment of tumors. However, the development of small molecular NIR-Ⅱ dyes is still challenging due to the limited electron acceptors and cumbersome synthetic routes.Herein, we report a novel molecular electron acceptor, boron difluoride formazanate(BDF). Based on BDF, a new small molecular NIR-Ⅱ dye BDF1005 is designed and synthesized with strong NIR-I absorption at 768 nm and bright NIR-Ⅱ peak emission at 1034 nm. In vitro and in vivo experiments demonstrate that BDF1005-based nanotheranostics can be applied for NIR-Ⅱ fluorescence imaging-guided photothermal therapy of 4T1 tumor-bearing mice. Under 808 nm laser irradiation, tumor growth can be effectively inhibited. This work opens up a new road for the exploitation of NIR-Ⅱ small molecular dyes for cancer phototheranostics. | Hanming Dai Zijin Cheng Tian Zhang Weili Wang Jinjun Shao Wenjun Wang Yongxiang Zhao Xiaochen Dong Liping Zhong | 2022 | Chinese Chemical Letters2022，33，5： | 1 |
| 16 | On-chip integrated optical stretching and electrorotation enabling single-cell biophysical analysis显示文摘Cells have different intrinsic markers such as mechanical and electrical properties,which may be used as specific characteristics.Here,we present a microfluidic chip configured with two opposing optical fibers and four 3D electrodes for multiphysical parameter measurement.The chip leverages optical fibers to capture and stretch a single cell and uses 3D electrodes to achieve rotation of the single cell.According to the stretching deformation and rotation spectrum,the mechanical and dielectric properties can be extracted.We provided proof of concept by testing five types of cells(HeLa,A549,HepaRG,MCF7 and MCF10A)and determined five biophysical parameters,namely,shear modulus,steady-state viscosity,and relaxation time from the stretching deformation and area-specific membrane capacitance and cytoplasm conductivity from the rotation spectra.We showed the potential of the chip in cancer research by observing subtle changes in the cellular properties of transforming growth factor beta 1(TGF-β1)-induced epithelial–mesenchymal transition(EMT)A549 cells.The new chip provides a microfluidic platform capable of multiparameter characterization of single cells,which can play an important role in the field of single-cell research. | Liang Huang Fei Liang Yongxiang Feng Peng Zhao Wenhui Wang | 2020 | Microsystems & Nanoengineering2020，6，1： | 1 |
| 17 | An impedance measurement method for double-gap klystron cavity显示文摘 | Zhao Yongxiang | 1982 | IEEE Trans on Electron Devices1982，29，2： | 1 |
| 18 | Photocrosslinkable Col/PCL/Mg composite membrane providing spatiotemporal maintenance and positive osteogenetic effects during guided bone regeneration显示文摘Guided bone regeneration membranes have been effectively applied in oral implantology to repair bone defects.However,typical resorbable membranes composed of collagen(Col)have insufficient mechanical properties and high degradation rate,while non-resorbable membranes need secondary surgery.Herein,we designed a photocrosslinkable collagen/polycaprolactone methacryloyl/magnesium(Col/PCLMA/Mg)composite membrane that provided spatiotemporal support effect after photocrosslinking.Magnesium particles were added to the PCLMA solution and Col/PCLMA and Col/PCLMA/Mg membranes were developed;Col membranes and PCL membranes were used as controls.After photocrosslinking,an interpenetrating polymer network was observed by scanning electron microscopy(SEM)in Col/PCL and Col/PCL/Mg membranes.The elastic modulus,swelling behavior,cytotoxicity,cell attachment,and cell proliferation of the membranes were evaluated.Degradation behavior in vivo and in vitro was monitored according to mass change and by SEM.The membranes were implanted into calvarial bone defects of rats for 8 weeks.The Col/PCL and Col/PCL/Mg membranes displayed much higher elastic modulus(p<0.05),and a lower swelling rate(p<0.05),than Col membranes,and there were no differences in cell biocompatibility among groups(p>0.05).The Col/PCL and Col/PCL/Mg membranes had lower degradation rates than the Col membranes,both in vivo and in vitro(p<0.05).The Col/PCL/Mg groups showed enhanced osteogenic capability compared with the Col groups at week 8(p<0.05).The Col/PCL/Mg composite membrane represents a new strategy to display space maintenance and enhance osteogenic potential,which meets clinical needs. | Feilong Wang Dandan Xia Siyi Wang Ranli Gu Fan Yang Xiao Zhao Xuenan Liu Yuan Zhu Hao Liu Yongxiang Xu Yunsong Liu Yongsheng Zhou | 2022 | Bioactive Materials2022，7，7： | 1 |
| 19 | Exploring the binding mechanism of thioflavin-T to the β-amyloid peptide by blind docking method显示文摘Using blind dock method,we find that thioflavin-T(ThT) can bind to both monomers and fibrils of the full-length β-amyloid peptide(Aβ1-42) and has a higher binding affinity to the fibrils.It is shown that the hydrophobic interaction between the ligand(ThT) and substrate(Aβ1-42) are stronger than hydrogen bonds.Furthermore,ThT tends to be located near the C-terminus of Aβ monomer through hydrophobic and electrostatic interactions,while it tends to contact the residues Met35 and Gly27 of the fibril surface mainly through hydrophobic interaction.Finally,according to the docking results and ThT fluorescence assay,a kinetic equation is proposed to deduce the aggregation rate coefficient of Aβ1-42. | ZHAO DeSheng CHEN YongXiang LIU Qian ZHAO YuFen LI YanMei | 2012 | 中国科学:化学2012，42，2： | 1 |
| 20 | Effects of Liuwei Dihuang decoction on ion channels and synaptic transmission in cultured hippocampal neuron of rat显示文摘 | Sheng Yang Wenxia Zhou Yongxiang Zhang Cunyu Yan Yimin Zhao | 2006 | Journal of Ethnopharmacology2006，，2： | 1 |
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