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| 1 | SHRIMP zircon U-Pb dating for subduction-related gran-itic rocks in the northern part of east Junggar, Xinjiang显示文摘SHRIMP U-Pb zircon dating on the Xileketehalasu granodiorite porphyry and Kalasayi monodiorite porphyry that intrude middle Devonian Beitashan Formation at the north part of east Junggar region shows that they were formed at 381±6 Ma and 376±10 Ma respectively. They are interpreted as subduction-related granitic rocks, which is the first report that the isotopic ages for the granitic rocks range from 350 to 390 Ma. Another determined age for the Kalasayi monodiorite porphyry is 408±9 Ma, representing the age of underlain Lower Devonian volcanic rocks. Thus, the U-Pb dates suggest that the northeastward subduction of Junggar ocean from southwest occurred at 408 to 376 Ma (the real inter- val may be larger). Because the ore-bearing porphyry intruded following the formation of the volcanic rocks of middle Devonian Beitashan Formation, their tec- tonic setting is similar to the Andes Mountains that hosts world-class porphyry copper deposits, and the researched area could be regarded as a potential area for prospecting large porphyry copper deposits. | ZHANG Zhaochong YAN Shenghao CHEN Bailin ZHOU Gang HE Yongkang CHAI Fengmei HE Lixin WAN Yusheng | 2006 | Chinese Science Bulletin2006，51，8： | 43 |
| 2 | The characteristics of atmospheric CO_2 concentration variation of four national background stations in China显示文摘Atmospheric carbon dioxide is an important kind of greenhouse gas which influences global temperature. Its concentration variation could indicate the distribution of human and natural activities in various regions. Through the non-dispersive infrared method, flask sampling of atmospheric CO2 concen- tration was measured weekly at four national background stations including Waliguan, Shangdianzi, Lin’an, and Longfengshan. Based on the data collected from September 2006 to August 2007, along with the Waliguan station’s experience on in situ observational data processing, the selection methods for sampling data through the atmospheric background CO2 concentration analysis were preliminarily discussed. On the basis of this result, the variation features of the four typical regions’ atmospheric background CO2 concentration was analyzed for the first time. The results show that the atmospheric CO2 concentration at Waliguan, Shangdianzi, Lin’an, and Longfengshan is 383.5, 385.9, 387.8, and 384.3 ppm, respectively. During the research period, CO2 concentration at the Waliguan station changed slightly. However, the CO2 concentration changed sharply at the Shangdianzi and the Lin’an stations due to the great influence of human activities in the Jingjinji and the Changjiang Delta economic zones, and changed regularly with seasons at Longfengshan station under dual influences of human activities and plant photosynthesis. The results from this study can lay the foundation for more profound studies on atmospheric CO2 concentration level of different areas in China, and could be used to improve the understanding of carbon source and sink distribution. | LIU LiXin, ZHOU LingXi, ZHANG XiaoChun, WEN Min, ZHANG Fang, YAO Bo & FANG ShuangXi Key Laboratory for Atmospheric Chemistry, Centre for Atmosphere Watch and Services (CAWAS), Chinese Academy of Meteoro- logical Sciences (CAMS), China Meteorological Administration (CMA), Beijing 100081, China | 2009 | Science China Earth Sciences2009，52，11： | 26 |
| 3 | Role of locust Locusta migratoria manilensis claws and pads in attaching to substrates显示文摘The present study attempts to investigate the role of rigid claws and smooth adhesive pads in the locust Locusta migratoria manilensis,when attaching to various substrates.We measured the attachment forces on sandpaper and silicate glass plate of locusts with intact attachment system,and those with either the pretarsal claws or the tarsal pads having been entirely destroyed,to explore the role of pads and claws when a locust is walking on various substrates.To obtain information about morphological characteristics and material properties of the claws,we examined the intact and fractured claws by scanning electron microscopy,and tested the fractural force in a fracture experiment.We proposed a mechanical model for locust climbing on a slanting surface to analyze the conduction and final result of the attachment forces generated by the attachment organs on the fore-,mid-and hindlegs.Attachment forces generated by locusts with destroyed pads were similar to those generated by locusts with intact attachment system on both substrates,which presumably indicated that the claws have a significantly important role when attaching to various substrates.The result of the fracture experiment demonstrated that the claws are made of relatively stiff material,and their shear strength ranged between 39-45 MPa.Mechanical analysis of locust climbing on slanting surface showed that the force generated by the hindlegs suspended the whole body of locust up from the surface and pushed the body forward,while the midlegs steadily suspended the centre of gravity and the forelegs pulled the suspended body forward.The results obtained contribute to the further interpretation of the interaction mechanisms between insect attachment system and substrates,and supply information for designing and manufacturing slippery plates for trapping plague locusts. | WANG LiXin ZHOU Qiang XU ShuYan | 2011 | Chinese Science Bulletin2011，56，8： | 13 |
| 4 | Discussion on the relationship between the Yanshanian Movement and cratonic destruction in North China显示文摘The relationship between the Yanshanian Movement, destruction of the North China Craton(NCC), and subduction of the western Pacific plate is crucial to reconstructing the middle-late Mesozoic tectonic evolution of the eastern Asian continent and margin. The Yanshanian Movement was a globally important change in crustal tectonics during the Middle-Late Jurassic.Previous research has systematically studied the formation and evolution of the Yanshanian Movement, focusing on the timing and location of tectonic movements, and the sedimentary and volcanic strata. However, the question of whether the tectonic activity occurred globally, and the characteristics of the Yanshanian Movement remain debated. The main argument is that if a tectonic movement can only be characterized by a regional or local disconformity, and if the tectonic movement occurred in an intracontinental setting, with extensive deformation but with no disconformity despite volcanic eruptions and magmatic intrusions, accompanied by changes in crustal structure and composition, should it be defined as a tectonic event or process? This question requires further analysis. The main aim of this study is to distinguish whether the Yanshanian Movement is a local feature of the eastern Asian continent, or a global tectonic event related to subduction of the Pacific Plate. In this paper, based on previous research, we discuss the spatial and temporal evolution of the Yanshanian Movement, the controlling tectonic mechanisms, and its relationship to the reactivation and destruction of the NCC and the subduction of the western Paleo-Pacific slab.We emphasize that the Yanshanian Movement in the Middle-Late Jurassic is distinct from the lithospheric thinning responsible for Early Cretaceous extension and magmatism related to the destruction of the NCC. The various tectonic stages were constrained by different dynamics and tectonic settings, or by different tectonic events and processes. Therefore, it is possible that the deformation and reactivation of the NCC contributed to its destruction, in addition to lithospheric thinning. Finally, we discuss whether the Yanshanian Movement was associated with the destruction of the NCC. | Yu WANG Lixin SUN Liyun ZHOU Yueting XIE | 2018 | Science China Earth Sciences2018，61，5： | 13 |
| 5 | Downwash distribution of single-rotor unmanned agricultural helicopter on hovering state显示文摘The effective coverage and velocity of downwash are directly related to the assemblage of spraying system and spraying effect.The downwash of the unmanned agricultural helicopter(UAH)N-3 was discussed in the paper.The computational fluid dynamics(CFD)methods were used to simulate and analyze the distribution of the downwash,and a wind field measurement device had been designed to test the downwash of UAH N-3.In the tests,the UAH N-3 was raised up to 5.0 m,6.0 m and 7.0 m from the ground,“annular-radial-distribution-point”method was introduced,8 directions separated by an angle of 45°(the radial direction)with the intersection point of the main rotor shaft and the ground plane as the center,0.5 m as the step length for the longitudinal(to 2.5 m)and radial(to 4.0 m)direction to set the sample points,considering the range of the rotor rotating circular area mainly.The 5 m height results of N-3 were fully discussed to describe the downwash distribution with the longitudinal altitude increased and the radial distance increased.The standard deviations of five test altitudes for eight directions were comparatively analyzed,the results showed that the total standard deviation was not greater than 0.6 m/s.The overall relative maximum margin of error calculated from the simulation and measurement data was between 0.6 and 0.7,which verified the credibility of the simulation data.High-order polynomials were used to fitting the simulation and measurement data,the fitting results showed that the polynomial coefficient of determination R^(2) met or exceeded 0.75 when the altitudes were more than 1 m,indicating the fit equation having the reference values.When the altitudes equal or less than 0.5 m,the polynomial coefficient of determination R^(2) was smaller,ranging during 0.3 to 0.7.The study would provide some foundations for the optimization of the assemblage of spraying system on the single-rotor UAH,which would promote China aviation plant protection. | Zhang Songchao Xue Xinyu Sun Zhu Zhou Lixin Jin Yongkui | 2017 | International Journal of Agricultural and Biological Engineering2017，10，5： | 13 |
| 6 | The Hippo signaling pathway in liver regeneration and tumorigenesis显示文摘表明小径的河马是在肝尺寸控制和 tumorigenesis 起关键作用的一个 evolutionarily 保存的发信号的模块。河马小径由在的核心 kinase 串联组成哺乳动物的象 Ste20 一样 kinases (Mst1/2,果蝇河马的 orthologs ) 并且他们的余因子萨尔瓦多(Sav1 ) 形成建筑群到 phosphorylate 并且激活大肿瘤 suppressor (Lats1/2 ) 。Lats1/2 kinases 接着 phosphorylate 并且与 PDZ 有约束力的主题(TAZ ) 禁止抄写激活剂,联系是的蛋白质(笨蛋) 和 transcriptional 激活剂,河马小径的二个主要下游的受动器。河马小径部件的损失导致异常肝肿大和 tumorigenesis,笨蛋在协调房间增长和 apoptosis 的规定并且起一个必要作用。这评论总结在肝新生和 tumorigenesis 发信号的河马的规定的当前的调查结果,集中河马小径的肿瘤 suppressor 部件的损失怎么导致肝癌症并且讨论调整它在肝 tumorigenesis 的下游的受动器笨蛋的表示和激活的分子的机制。 | Lixin Hong Yabo Cai Mingting Jiang Dawang Zhou Lanfen Chen | 2015 | Acta Biochimica et Biophysica Sinica2015，47，1： | 12 |
| 7 | Investigation of the sliding friction behaviors of locust on slippery plates显示文摘The slippery trapping plate in swarm locust control is a method of realizing resource utilization of locust and avoiding pesticide residues in the entironment. Some slippery plates with different material composition or surface characteristic were investigated through the sliding tests of locust on slippery plates, and sliding rubbing behaviors of locusts on the plate were observed by means of CCD video monitoring system. Poor sliding character of silicate glass to locust was verified, which is in accordance with the adhesive effect generated by secretion of locust feet pads on the smooth surface. And also, PVC plastic plate presents a poor sliding character to locusts, because the soft surface of PVC can permit claws of locust feet to engender mechanical interlock on the surface. The zinc plate shows a considerable slippery ratio for locusts because of the appropriate surface characteristic and material property. Photoelectric stimulation for resting locust can promote the movement of locust. Accordingly, the contact form of locust feet and abdomen on slippery plates is changed and contact area is reduced severely, so the sliding effect of locust on slippery plates is strengthened effectively. These results supply a suitable theoretical foundation for manufacturing locust slippery trapping plates and trapping units, and indicate the important role of photoelectric stimulating factors in biotribology. | WANG LiXin ZHOU Qiang Xu ShuYan Niu HuLi | 2009 | Chinese Science Bulletin2009，54，24： | 11 |
| 8 | SHRIMP U-Pb Zircon Age of the Ka'erjiao Intrusion in the Sawur Region in West Junggar,Xinjiang显示文摘摘要:酸侵入在 Sawur 区域是普遍的, Xinjiang。Ka'erjiao 侵入主要由钠长石花岗石斑岩, K 长石花岗石斑岩, ivernite 和花岗石斑岩组成。在 Sawur 区域是在岩浆侵入和爆发之间的一个过渡产品, Ka'erjiao 侵入在未期被形成对开始晚含碳作为早二叠由标明日期的 SHRIMP U-Pb 锆石决定了,与 302.6 | ZHOU Taofa TAN Lugui FAN Yu YUAN Feng YANG Wenping HE Lixin YUE Shucang | 2007 | Acta Geologica Sinica(English Edition)2007，81，2： | 9 |
| 9 | Nepenthes pitchers:surface structure,physical property,anti-attachment function and potential application in mechanical controlling plague locust显示文摘Pitchers plants of Nepenthes specie growing in infertile habitats have developed highly specialized apparatus for trapping and digesting arthropods to obtain sufficient growing nutrients.Nepenthes pitchers are generally recognized by several distinguishably morphological zones,and different districts exhibit distinct functions in prey capturing,combined effect of the several zones results in great trapping efficiency.This prey ability of Nepenthes pitchers potentially inspires an idea for biomimetic development of slippery trapping plate used in controlling agricultural pests,especially plague locust.In this paper,we reviewed the recent researches of Nepenthes pitchers,including surface structures,physical properties,and antiattachment functions.Apart from this,combined with our latest studies on mechanical controlling plague locust,the potential application of Nepenthes pitchers as establishing biomimetic models utilized in creating trapping plate was addressed,and several corresponding aspects requiring to be paid attention to in near future were also highlighted. | Lixin Wang Qiang Zhou | 2014 | Chinese Science Bulletin2014，59，21： | 8 |
| 10 | Slippery Surface of Nepenthes alata Pitcher: The Role of Lunate Cell and Wax Crystal in Restricting Attachment Ability of Ant Camponotus japonicus Mayr显示文摘 | Lixin Wang Shiyun Dong Qiang Zhou | 2016 | Journal of Bionic Engineering2016，13，3： | 8 |
| 11 | Simulation of CO_2 variations at Chinese background atmospheric monitoring stations between 2000 and 2009: Applying a CarbonTracker model显示文摘We carried out a downscaling treatment over China using the CarbonTracker numerical model,which was applied using double grid nesting technology(3°×2°over the whole globe,1°×1°over China),simulating and analyzing atmospheric CO2concentrations over 10 recent years(2000–2009).The simulation results agreed very well with observed data from four background atmospheric monitoring stations in China(The periods for which the simulation results and observed values be compared were January2000 to December 2009 for the WLG station and June 2006 to December 2009 for the SDZ,LFS,and LAN stations),giving correlation coefficients of>0.7.The high-resolution simulation data correlated slightly better than the low resolution simulation data with the observed data for three of the regions’atmospheric background stations.Further analysis of the annual,seasonal CO2concentration variations at the background stations showed that the CO2concentration increased each year over the study period,with an average annual increase of more than 5%,and annual increases of more than 7%at the Shangdianzi and Lin’an stations.Seasonal CO2variations were greater at the Longfengshan station than at the Shangdianzi or Lin’an stations.However,the CO2concentrations were higher at the Shangdianzi and Lin’an stations because they are greatly affected by human activities in the Jingjinji and Changjiang Delta economic zones.Spatial distribution in CO2concentrations and fluxes were higher in eastern than in western China. | CHENG YanLi AN XingQin YUN FangHua ZHOU LingXi LIU LiXin FANG ShuangXi XU Lin | 2013 | Chinese Science Bulletin2013，58，32： | 8 |
| 12 | Composite structure and properties of the pitcher surface of the carnivorous plant Nepenthes and its influence on the insect attachment system显示文摘食肉的植物能使人忘忧的东西的投球手发展了服务吸引的目的专业化器官,捕获,保留并且消化小动物,主要昆虫。他们由几个很好可区分的地区组成,包括一个像叶子的盖,像领子的蒴齿,一个滑溜溜的地区和一个消化地区,在形态学,微观结构,化学作文和物理性质不同。区别地区显示不同功能,并且几个地区的联合效果导致套住效率的伟人。这评论的主要目的是介绍结构和投球手表面,以及在投球手表面和昆虫附件系统之间的相互作用的 physiochemical 性质。与我们的现在的学习结合,投球手表面的潜在的应用程序在 bionics 正在被利用生产昆虫滑溜溜的套住盘子被讨论,并且投球手表面的创新研究方向和它农业害虫控制上的应用程序被加亮。 | Lixin Wang Qiang Zhou Yongjun Zheng Shuyan Xu | 2009 | Progress in Natural Science:Materials International2009，19，12： | 8 |
| 13 | Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes显示文摘Objective: There are no comprehensive studies on survival outcomes and optimal treatment protocols for cervical esophageal cancer(CEC), due to its rare clinical prevalence. Our objective was to determine the relationship between pathological characteristics, treatment protocols, and survival outcomes in Chinese CEC patients.Methods: A total of 500 Chinese CEC patients were selected from our 500,000 esophageal and gastric cardia carcinoma database(1973–2018). There were two main groups: patients treated with surgery, and patients receiving non-surgical treatments(radiotherapy, radiochemotherapy, and chemotherapy). The Chi-square test and Kaplan–Meier method were used to compare the continuous variables and survival.Results: Among the 500 CEC patients, 278(55.6%) were male, and the median age was 60.9 ± 9.4 years. A total of 496 patients(99.2%) were diagnosed with squamous cell carcinoma. In 171(34.2%) patients who received surgery, 22(12.9%) had undergone laryngectomy. In 322(64.4%) patients who received non-surgical treatments, 245(76.1%) received radiotherapy. Stratified survival analysis showed that only T stage was related with survival outcomes for CEC patients in the surgical group, and the outcomes between laryngectomy and non-laryngectomy patients were similar. It was noteworthy that the 5-year survival rate was similar in CEC patients among the different groups treated with surgery, radiotherapy, chemotherapy, or radiochemotherapy(P = 0.244). Conclusions: The CEC patients had similar survival outcomes after curative esophagectomy and radiotherapy, including those with or without total laryngectomy. These findings suggest that radiotherapy could be the initial choice for treatment of Chinese CEC patients. | Peinan Chen Xueke Zhao Fuyou Zhou Xin Song Shoujia Hu Yan Jin Xianzeng Wang Xuena Han ZongminFan Ran Wang Bei Li Wenli Han Panpan Wang Jilin Li Lixin Wan Liguo Zhang Qide Bao Fubao Chang Yanru Qin Zhiwei Chang Jianwei Ku Haijun Yang Ling Yuan Jingli Ren Xuemin Li Lidong Wang | 2020 | Cancer Biology & Medicine2020，17，1： | 6 |
| 14 | Comparison of efficacy, safety, and quality of life between sorafenib and sunitinib as first.line therapy for Chinese patients with metastatic renal cell carcinoma显示文摘Background: Sorafenib and sunitinib are widely used as first-line targeted therapy for metastatic renal cell carcinoma(mRCC) in China.This study aimed to compare the efficacy, safety, and quality of life(QoL) in Chinese mRCC patients treated with sorafenib and sunitinib as first-line therapy.Methods: Clinical data of patients with mRCC who received sorafenib(400 mg twice daily; 4 weeks) or sunitinib(50 mg twice daily; on a schedule of 4 weeks on treatment followed by 2 weeks off) were retrieved. Primary outcomes were overall survival(OS), progression-free survival(PFS), adverse events(AEs), and QoL(SF-36 scores), and secondary outcomes were associations of clinical characteristics with QoL.Results: Medical records of 184 patients(110 in the sorafenib group and 74 in the sunitinib group) were reviewed.PFS and OS were comparable between the sorafenib and sunitinib groups(both P > 0.05).The occurrence rates of leukocytopenia, thrombocytopenia, and hypothyroidism were higher in the sunitinib group(36.5% vs. 10.9%,P< 0.001; 40.5% vs. 10.9%, P < 0.001; 17.6% vs. 3.6%, P = 0.001), and that of diarrhea was higher in the sorafenib group(62.7% vs. 35.2%, P < 0.001). There was no significant difference in SF-36 scores between the two groups. Multivariate analysis indicated that role-physical and bodily pain scores were associated with the occurrence rate of grade 3 or 4 AEs(P = 0.017 and 0.005).Conclusions: Sorafenib has comparable efficacy and lower toxicity profile than sunitinib as first-line therapy for mRCC. Both agents showed no significant impact on QoL of patients. | Wen Cai Wen Kong Baijun Dong Jin Zhang Yonghui Chen Wei Xue Yiran Huang Lixin Zhou Jiwei Huang | 2017 | Chinese Journal of Cancer2017，36，11： | 6 |
| 15 | Influence of Indian Ocean Dipole on Tropical Cyclone Activity over Western North Pacific in Boreal Autumn显示文摘In this study, we investigated the influence of the Indian Ocean Dipole (IOD) on the interannual variability of tropical cyclone (TC) activity over the western North Pacific (WNP) during autumn (September November) from 1961 2015. We found the number of TCs making landfall in China to be significantly negatively correlated with the IOD index, which can be attributed to shifts in the location of TC formation together with the abnormal steering flow at 500 hPa. During negative IOD autumns, TC genesis regions move obviously westward due to the westward retreat of the WNP monsoon trough. The TC activity is remarkably enhanced near South China coastal areas, which is due to a contiguous 500-hPa subtropical ridge. In contrast, during positive IOD autumns, TC genesis positions obviously shift eastward and more TCs tend to exhibit recurvature around 130 E or a westward path south of 15 N led by an equatorward movement of the 500-hPa subtropical ridge with a break near 125 E. In our examination of large-scale circula- tion, we found a pair of equator-symmetric anticyclones in the lower troposphere resulting from variations in the large-scale Walker circulation induced by the anomalous sea surface temperature (SST) associated with a positive IOD. The resulting Philippines anti- cyclonic anomalies are closely related to the variability of the monsoon trough over the WNP region. Furthermore, the variations in the steering flow can be explained by the suppressed (enhanced) convective activities around the Philippines and the weakened (strengthened) local meridional circulation over East Asia in positive (negative) IOD years. | ZHOU Qun WEI Lixin ZHANG Runyu | 2019 | Journal of Ocean University of China2019，18，4： | 6 |
| 16 | Self-starting passively mode-locked all fiber laser based on carbon nanotubes with radially polarized emission显示文摘We demonstrate an all fiber passively mode-locked laser emitting a radially polarized beam by using a few-mode fiber Bragg grating to achieve mode selection and spectrum filtering. An offset splicing of single-mode fiber with four-mode fiber is utilized as a mode coupler in the laser cavity. Carbon nanotubes are introduced into the laser cavity as the saturable absorber to achieve self-start mode locking. The laser operates at 1547.5 nm with a narrow spectrum width of 0.3 nm at 30 d B. The emitted mode-locked pulses have a duration of 22.73 ps and repetition of10.61 MHz. A radially polarized beam has been obtained with high mode purity by adjusting the polarization in the laser cavity. | Yong Zhou Jian Lin Xiaoqiang Zhang Lixin Xu Chun Gu Biao Sun Anting Wang Qiwen Zhan | 2016 | Photonics Research2016，4，6： | 6 |
| 17 | High He-ion irradiation resistance of CrMnFeCoNi high-entropy alloy revealed by comparison study with Ni and 304SS显示文摘High entropy alloys(HEAs) have presented potential applications in nuclear power plants owing to their novel atomic structure based high irradiation resistance. However, understanding of He-ion irradiation of HEAs is still lacking. In this work, we reveal He-ion irradiation resistance of HEA CrMnFeCoNi by comparison study with a pure Ni and a 304 stainless steel(304SS). It is found that the damage structure in the three materials can be characterized with He bubbles and stacking faults/stacking fault tetrahedrons((SFs/SFTs), which show a similar depth distribution after He-ion irradiation at both RT and 450℃.Although the He bubbles have a similar size about 2nm after irradiation at RT, the He bubble sizes of the HEA, 304SS, and Ni increase to 4.0±0.9,5.3±1.0 and 6.7 ±1.0 nm after irradiation at 450℃, respectively. Moreover, the density of SFs/SFTs displays in an order of Ni < 304 SS < HEA at both RT and 450℃.The He-ion irradiation at RT causes significant hardness enhancement for the three materials, however,compared to RT, after irradiation at 450℃, the Ni presents softening, while the 304SS, especially the HEA,shows further hardening. Thus, the HEA CrMnFeCoNi possesses the smallest He bubble size, the densest SFs/SFTs, and the highest hardening, indicating the best structural stability, as well as the best He-ion irradiation resistance, which can be attributed to its low mobility of He atoms and point defects. | Lixin Yang Hualong Ge Jian Zhang Ting Xiong Qianqian Jin Yangtao Zhou Xiaohong Shao Bo Zhang Zhengwang Zhu Shijian Zheng Xiuliang Ma | 2019 | Journal of Materials Science & Technology2019，35，3： | 5 |
| 18 | Role of Hippo signaling in regulating immunity显示文摘The Hippo signaling pathway has been established as a key regulator of organ size control,tumor suppression,and tissue regeneration in multiple organisms.Recently,emerging evidence has indicated that Hippo signaling might play an important role in regulating the immune system in both Drosophila and mammals.In particular,patients bearing a loss-of-function mutation of MST1 are reported to have an autosomal recessive primary immunodeficiency syndrome.MST1/2 kinases,the mammalian orthologs of Drosophila Hippo,may activate the non-canonical Hippo signaling pathway via MOB1A/B and/or NDR1/2 or cross-talk with other essential signaling pathways to regulate both innate and adaptive immunity.In this review,we present and discuss recent findings of cellular mechanisms/functions of Hippo signaling in the innate immunity in Drosophila and in mammals,T cell immunity,as well as the implications of Hippo signaling for tumor immunity. | Lixin Hong Xun Li Dawang Zhou Jing Geng Lanfen Chen | 2018 | Cellular & Molecular Immunology2018，15，12： | 5 |
| 19 | DeST 3.0:A new-generation building performance simulation platform显示文摘Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in novel building technologies,the requirements of high-performance computation,and the demands for multi-objective models have brought new challenges for building energy modeling software and platforms.To meet the increasing simulation demands,DeST 3.0,a new-generation building performance simulation platform,was developed and released.The structure of DeST 3.0 incorporates four simulation engines,including building analysis and simulation(BAS)engine,HVAC system engine,combined plant simulation(CPS)engine,and energy system(ES)engine,connected by air loop and water loop balancing iterations.DeST 3.0 offers numerous new simulation features,such as advanced simulation modules for building envelopes,occupant behavior and energy systems,cross-platform and compatible simulation kernel,FMI/FMU-based co-simulation functionalities,and high-performance parallel simulation architecture.DeST 3.0 has been thoroughly evaluated and validated using code verification,inter-program comparison,and case-study calibration.DeST 3.0 has been applied in various aspects throughout the building lifecycle,supporting building design,operation,retrofit analysis,code appliance,technology adaptability evaluation as well as research and education.The new generation building simulation platform DeST 3.0 provides an efficient tool and comprehensive simulation platform for lifecycle building performance analysis and optimization. | Da Yan Xin Zhou Jingjing An Xuyuan Kang Fan Bu Youming Chen Yiqun Pan Yan Gao Qunli Zhang Hui Zhou Kuining Qiu Jing Liu Yan Liu Honglian Li Lei Zhang Hong Dong Lixin Sun Song Pan Xiang Zhou Zhe Tian Wenjie Zhang Ruhong Wu Hongsan Sun Yu Huang Xiaohong Su Yongwei Zhang Rui Shen Diankun Chen Guangyuan Wei Yixing Chen Jinqing Peng | 2022 | Building Simulation2022，15，11： | 5 |
| 20 | Experimental research on rotating detonation with liquid hypergolic propellants显示文摘This paper describes experimental research into the initiation and propagation of rotating detonation for liquid Nitrogen TetrOxide(NTO) and liquid MonoMethylHydrazine(MMH).An annular rocket-type combustor without nozzle was designed to investigate detonation combustion. The propellants were injected through unlike impingement injectors. The combustion flame fronts and pressure waves were detected using optical diagnostics and dynamic pressure sensors,respectively. The propagation of rotating detonation was established spontaneously by increasing the mass flow rate of propellants. The velocity of propagation of the flame fronts and pressure waves was nearly equal and reaches supersonic speed. Two different detonation combustion patterns are present, single wave mode and double waves mode. And in double waves mode, the two detonation waves are always counter-rotating. The possibility of rotating detonation initiation in a combustor with nozzle was also checked. Stable rotating detonation can be initialized and sustained at similar operating conditions. | Shuaijie XUE Hongjun LIU Lixin ZHOU Weidong YANG Hongbo HU Yu YAN | 2018 | Chinese Journal of Aeronautics2018，31，12： | 5 |
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