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| 1 | Study on the Hydrophobic Property of Shark-Skin-Inspired Micro-Riblets显示文摘 | Danyang Zhao Qianqian Tian Minjie Wang Yifei Jin | 2014 | Journal of Bionic Engineering2014，11，2： | 6 |
| 2 | Oxide-based cathode materials for rechargeable zinc ion batteries:Progresses and challenges显示文摘With the increasing demands for electrical energy storage technologies,rechargeable zinc ion batteries(ZIBs)have been rapidly developed in recent years owing to their high safety,low cost and high energy storage capability.The cathode is an essential part of ZIBs,which hosts zinc ions and determines the capacity,rate and cycling performance of the battery.The mainstream cathodes for ZIBs are oxidebased materials with tunnel,layer or 3 D crystal structures.In this review,we mainly focus on the latest advanced oxide-based cathode materials in ZIBs,including manganese oxides,vanadium oxides,spinel compounds,and other metal oxide based cathodes.In addition,the mechanisms of zinc storage and recent development in cathode design have been discussed in detail.Finally,current challenges and perspectives for the future research directions of oxide-based cathodes in ZIBs are presented. | Yingze Zhou Fandi Chen Hamidreza Arandiyan Peiyuan Guan Yunjian Liu Yuan Wang Chuan Zhao Danyang Wang Dewei Chu | 2021 | Journal of Energy Chemistry2021，30，6： | 4 |
| 3 | LncDACH1 promotes mitochondrial oxidative stress of cardiomyocytes by interacting with sirtuin3 and aggravates diabetic cardiomyopathy显示文摘Diabetic cardiomyopathy(DCM)is a common complication in diabetic patients.The molecular mechanisms of DCM remain to be fully elucidated.The intronic long noncoding RNA of DACH1(lnc DACH1)has been demonstrated to be closely associated with heart failure and cardiac regeneration.In this study,we investigated the role of lnc DACH1 in DCM and the underlying molecular mechanisms.The expression of lnc DACH1 was increased in DCM hearts and in high glucose-treated cardiomyocytes.Knockout of lnc DACH1 reduced mitochondrial oxidative stress,cell apoptosis,cardiac fibrosis and hypertrophy,and improved cardiac function in DCM mice.Overexpression of lnc DACH1 exacerbated mitochondria-derived reactive oxygen species(ROS)level and apoptosis,decreased activity of manganese superoxide dismutase(Mn-SOD);while silencing of lnc DACH1 attenuated ROS production,mitochondrial dysfunction,cell apoptosis,and increased the activity of Mn-SOD in cardiomyocytes treated with high glucose.Lnc DACH1 directly bound to sirtuin3(SIRT3)and facilitated its degradation by ubiquitination,therefore promoting mitochondrial oxidative injury and cell apoptosis in mouse hearts.In addition,SIRT3 silencing abrogated the protective effects of lnc DACH1 deficiency in cardiomyocytes.In summary,lnc DACH1 aggravates DCM by promoting mitochondrial oxidative stress and cell apoptosis via increasing ubiquitination-mediated SIRT3 degradation in mouse hearts.Inhibition of lnc DACH1 represents a novel therapeutic strategy for the intervention of diabetic cardiomyopathy. | Qi Zhang Danyang Li Xue Dong Xiaowen Zhang Junwu Liu Lili Peng Bo Meng Qi Hua Xinyu Pei Lu Zhao Xiaoxi Hu Yang Zhang Zhenwei Pan Yanjie Lu Baofeng Yang | 2022 | Science China(Life Sciences)2022，65，6： | 4 |
| 4 | Neural cell injury microenvironment induces neural differentiation of human umbilical cord mesenchymal stem cells显示文摘 | Jin Zhou Guoping Tia Jinge Wang Xiaoguang Luo Siyang Zhang Jianping Li Li Li Bing Xu FengZhu Xia Wang Chunhong Jia Weijin Zhao Danyang Zhao Aihua Xu | 2012 | Neural Regeneration Research2012，7，34： | 3 |
| 5 | Payments for watershed ecosystem services:mechanism,progress and challenges显示文摘Introduction:Payment for watershed ecosystem services(PWES),a policy instrument for compensating for the externality of watershed ecosystem/environmental services,has gained in policy importance in China over the past two decades.Many scholars and researchers have contributed to the conceptualization of this policy framework by developing operational mechanisms as well as compensation standards for PWES.Outcomes:This article reviews 27 PWES schemes piloted in China and in 10 other countries,with a particular emphasis on successful cases of land-use conversion programs,such as the Paddy Land to Dry Land Program and Sloping Land Conversion Program that have been implemented in China.Discussion:By comparing different cases,the authors attempt to answer the following questions:what were the ecological and institutional contexts in which these schemes were established and how did they work?What were the actual efficiencies and impacts of these piloted schemes?Which scheme worked better in certain ecological,socio-economic,and institutional contexts?Conclusion:Based on case studies,the authors draw the following conclusions about Chinese PWES:(1)to establish an acceptable standard for a PWES program,it is necessary to estimate the economic and social costs regarding the livelihoods of households;(2)multistakeholder negotiation mechanism for PWES,including intermediaries,such as the local government,NGO/NPOs,village committees,and user associations,should be used;(3)ES,non-market services,should acquire positive externalities to accomplish an optimal win–win pattern concerning both environmental goals and the livelihoods of local resource users. | Danyang Feng Wenliang Wu Long Liang Li Li Guishen Zhao | 2018 | Ecosystem Health and Sustainability2018，4，1： | 2 |
| 6 | Validation results of NmF2 and hmF2 derived from ionospheric density profiles of GNOS on FY-3C satellite显示文摘The first Global Navigation Satellite System Occultation Sounder(GNOS) which is compatible of both Bei Dou System(BDS)and Global Positioning System(GPS) was successfully launched into orbit onboard the Feng Yun 3 C satellite(FY-3 C) on September 23, 2013, and it has already gathered a large amount of ionosphere radio occultation(RO) data so far. However, the detailed analysis and validation of GPS ionosphere RO data have not been done up to now. Therefore, this paper discusses the configuration of the FY-3 C GNOS, the methods and results of GPS ionosphere occultation processment, the quality analysis of the GPS ionosphere RO products, and the precision consistency between the GNOS GPS ionosphere RO product and ionosonde data. The peak electron density(Nm F2) correlation coefficient is 0.97, the corresponding standard deviation is 16.08%. The peak value altitude(hm F2) correlation coefficient is 0.89, and the corresponding standard deviation is 23.79 km. The in-orbit operation of GNOS provides a basis data set for the monitoring, forecasting and research of ionosphere's space weather. | YANG GuangLin SUN YueQiang BAI WeiHua ZHANG XiaoXin LIU CongLiang MENG XiangGuang BI YanMeng WANG DongWei ZHAO DanYang | 2018 | Science China(Technological Sciences)2018，61，9： | 2 |
| 7 | Study of extrudability and standoff distance effect during nanoclay-enabled direct printing显示文摘 | Yifei Jin Danyang Zhao Yong Huang | 2018 | Bio-Design and Manufacturing2018，1，2： | 2 |
| 8 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 9 | Adenosine triphosphate-sensitive potassium channel opener protects PC12 cells against hypoxia-induced apoptosis through PI3K/Akt and Bcl-2 signaling pathways显示文摘Although previous studies have shown the neuroprotective effects of the adenosine triphosphate(ATP)-sensitive potassium(KATP) channel opener against ischemic neuronal damage,little is known about the mechanisms involved.Phosphatidylinositol-3 kinase(PI3K)/v-akt murine thy-moma viral oncogene homolog(Akt) and Bcl-2 are thought to be important factors that mediate neuroprotection.The present study investigated the effects of KATP openers on hypoxia-induced PC12 cell apoptosis,as well as mRNA and protein expression of Akt and Bcl-2.Results demon-strated that pretreatment of PC12 cells with pinacidil,a KATP opener,resulted in decreased PC12 cell apoptosis following hypoxia,as detected by Annexin-V fluorescein isothiocyanate/propidium iodide double staining flow cytometry.In addition,mRNA and protein expression of phosphory-lated Akt(p-Akt) and Bcl-2 increased,as detected by immunofluorescence,Western blot analysis,and reverse-transcription polymerase chain reaction.The protective effect of this preconditioning was attenuated by glipizide,a selective KATP blocker.These results demonstrate for the first time that the protective mechanisms of KATP openers on PC12 cell apoptosis following hypoxia could result from activation of the PI3K/Akt signaling pathway,which further activates expression of the downstream Bcl-2 gene. | Hong Zhang Chunhong Jia Danyang Zhao Yang Lu Runling Wang Jia Li | 2010 | Neural Regeneration Research2010，5，22： | 1 |
| 10 | Inhibitory of EV-A71 virus-induced apoptosis by ZVAD through ROS mediated signaling pathways显示文摘Emerging evidence that Enterovirus A 71(EV-A71)infection closely related to apoptosis.The ZVAD is a caspase inhibitor that can prevent apoptosis.The aims of this project were to evaluate the mechanism of the ZVAD inhibited EV-A71 virus and to provide experiment basis for finding new antiviral drugs.In this study,after treated with ZVAD in EV-A71 infected Vero cells,the viral replication was reduced,and the cell viability was higher than EV-A71 group.Additionally,ZVAD decreased the cell apoptosis and the level of inflammatory cytokines induced by EV-A71 in the infected Vero cells.ZVAD inhibited cell apoptosis by regulating ROS mediated signaling pathway and inflammation cytokines to achieve antiviral. | TIANTIAN XU RUILIN ZHENG DANYANG CHEN HAIYANG CHEN MINGQI ZHAO MIN GUO YI CHEN CHANGBING WANG LU KUANG YINGHUA LI BING ZHU | 2022 | BIOCELL2022，46，4： | 1 |
| 11 | Promoter and coding sequence diversity of CsCCD1 may contribute to the differential accumulation of floralβ-ionone in fresh tea leaves显示文摘The carotenoid-derived volatileβ-ionone makes an important contribution to tea fragrance.Here,we qualitatively and quantitatively analysed 15 carotenoids in tea leaves of 13 cultivars by UHPLC-APCI-MS/MS.The 13 cultivars were divided into two groups by PCA(Principal Component Analysis)clustering analysis of their carotenoid content,and OPLS-DA(Orthogonal projections to latent structures)indicated that the levels ofβ-carotene(VIP=2.89)and lutein(VIP=2.30)were responsible for much of the variation between the two groups.Interestingly,theβ-carotene toβ-ionone conversion rates in Group 1 were higher than in Group 2,while theβ-carotene content was significantly lower in Group 1 than in Group 2.Theβ-ionone content was significantly higher in Group 1.Pearson Correlation Coefficient calculation between the transcription level of candidate genes(CsCCD1 and CsCCD4)and the accumulation ofβ-ionone indicated that CsCCD1 may involve in the formation ofβ-ionone in 13 cultivars.Prokaryotic expression and in vitro enzyme activity assays showed that‘Chuanhuang 1’had an amino acid mutation in carotenoid cleavage dioxygenases 1(CsCCD1)compared with‘Shuchazao’,resulting in a significantly higherβ-ionone content in‘Chuanhuang 1’.Sequence analysis showed that‘Chuanhuang 1’and‘Huangdan’had different CsCCD1 promoter sequences,leading to significantly higher CsCCD1 expression andβ-ionone accumulation in‘Chuanhuang 1’.These results indicated that the promoter and coding sequence diversity of CsCCD1 might contribute to the differential accumulation ofβ-ionone in different tea cultivars. | Jingming Wang Mingyue Zhao Ting Gao Yingying Feng Feiquan Wang Yuting Pan Jieyang Jin Tingting Jing Mengqian Lu Mengting Zhang Danyang Guo Xiaochun Wan Wilfried Schwab Chuankui Song | 2023 | Horticultural Plant Journal2023，9，4： | 1 |
| 12 | Reviews on sulphur corrosion phenomenon of the oil-paper insulating system in mineral oil transformer显示文摘The active sulphur compounds in transformer oil would react with copper wires and produce cuprous sulphides,which then attach themselves to the surface of copper wires and insulating paper,thus reducing the electrical performance of oil-paper insulation and causing insulation failure.This article aims to make a comprehensive summary on the field of sulphur corrosion of oil-paper insulation in the mineral oil transformer,including the corrosion mechanism of sulphide on copper sheets,the deterioration mechanism of sul-phide on oil-paper,the factors influencing sulphur corrosion reaction,the method of characterising the degree of sulphur corrosion,the protection technology of sulphur corrosion and the field operation measures for sulphur corrosion.Moreover,four key problems that need to be further solved were sorted out:the synergistic deterioration mechanism of sulphide and its transformation mechanism,the micro-process and forming path of sulphur corrosion reaction,the characteristic parameters and quantitative charac-terisation methods of sulphur corrosion degree,and the effective protection technology of sulphide corrosion.To solve these problems,efforts will be made for deeper understanding of the sulphur corrosion phenomenon and its deterioration mechanism based on theo-retical background,the assessment methods and protection technology,endeavouring to put forward solid theoretical basis and feasible technical means for preventing sulphur corrosion insulation failure. | Haoxi Cong Hao Pan Danyang Qian Haiyu Zhao Qingmin Li | 2021 | High Voltage2021，6，2： | 1 |
| 13 | Defect-induced electron rich nanodomains in CoSe_(0.5)S_(1.5)/GA realize fast ion migration kinetics as sodium-ion capacitor anode显示文摘Optimizing charge migration and alleviating volume expansion in anode materials are the key to improve the electrochemical performance for sodium-ion storage devices.Herein,a hierarchical porous conducting matrix confining defect-rich selenium doped cobalt dichalcogenide(CoSe_(0.5)S_(1.5)/GA)is constructed as a promising SICs anode based on the guidance of theoretical calculation analysis.The increased defect concentration significantly enhanced the disorder degree of the compound and presented electron aggregation around the S atoms,which effectively modulated the electronic structure,further enabling high rate and ultra-capacity sodium storage.Moreover,strong interfacial coupling could construct spatial constraint to alleviate volume expansion as well as maintain electrode integrity and stability.The CoSe_(0.5)S_(1.5)/GA electrode can deliver a high capacity of 310.1 mA h g^(-1)after 2000 cycles at 1 A g^(-1),and the CoSe_(0.5)S_(1.5)/GA//AC sodium ion capacitor can exhibit an outstanding energy density of 237.5 W h kg^(-1).A series of characterization and theoretical calculation convincingly reveal that the defect moieties can regulate the Na^(+)storage and diffusion kinetics,which prove that our defect manufacture coupling with space-confined strategy can provide deep insights into the development of high-performance Na^(+)storage devices. | Tianlin Li Danyang Zhao Binghui Du Qing Yin Yongzhi Li Xiaolan Xue Fuxiang Wei Jiqiu Qi Yanwei Sui | 2023 | Journal of Energy Chemistry2023，，12： | 0 |
| 14 | Advances in friction of aluminium alloy deep drawing显示文摘Broad use of lightweight aluminium alloy parts in automobile manufacturing,aerospace,electronic communication,and rail transit is mainly formed through deep drawing process.Deep drawing friction is a key boundary condition for controlling the forming quality of aluminium alloy parts.However,due to the oxidation and adhesion tendency of aluminium alloys,the tribological situations of aluminium alloy deep drawing(AADD)system is more complicated than those of traditional deep drawing of steel sheets.Therefore,the study of AADD friction is essential for manufacturing high-performance aluminium alloy parts.Herein,aiming to provide a valuable reference for researchers in related fields,a comprehensive review of AADD friction is provided,including friction mechanism,influencing factors,friction measurement,friction model,friction simulation,and lubrication-free friction control.Finally,a brief conclusion and several current challenges were discussed. | Yiren GAO Hongxia LI Danyang ZHAO Minjie WANG Xiaobo FAN | 2024 | Friction2024，12，3： | 0 |
| 15 | 3D Printing of Biodegradable Polymer Vascular Stents:A Review显示文摘Biodegradable polymer vascular stents(BPVSs)have been widely used in percutaneous coronary interventions for the treatment of coronary artery diseases.The development of BPVSs is an integrated process that combines material design/selection,manufacturing,and performance characterization.Three-dimensional(3D)printing technology is a powerful tool for polymer stent fabrication.Current review studies have focused primarily on the material and structural design of polymer stents but have failed to comprehensively discuss different 3D printing approaches and stent characterization techniques.In this paper,we address these shortcomings by discussing 3D printing methods and their application in BPVSs.First,some commonly used 3D printing methods(including material extrusion,vat polymerization,and powder bed fusion)and potential 3D printing strategies(including material jetting and binder jetting)for fabricating BPVSs are discussed;furthermore,the main post-treatments are summarized.Then,techniques to characterize the morphology,mechanical properties,and biological prop-erties of the printed BPVSs are introduced.Subsequently,representative commercial BPVSs and lab-grade BPVSs are compared.Finally,based on the limitations of stent printing and characterization processes,future perspec-tives are proposed,which may help develop new techniques to fabricate more customized stents and accurately evaluate their performance. | Weijian Hua Weiliang Shi Kellen Mitchell Lily Raymond Ryan Coulter Danyang Zhao Yifei Jin | 2022 | Chinese Journal of Mechanical Engineering(Additive Manufacturing Frontiers)2022，1，2： | 0 |
| 16 | Process-microstructure-properties of CuAlNi shape memory alloys fabricated by laser powder bed fusion显示文摘Cu-based shape memory alloys(SMAs)show great potential in the application of high temperature,but their performance improvement combining with additive manufacturing is still challenging.In this paper,nearly defect-free(99.7%relative density)CuAlNi SMAs with two types of thermal-induced martensites,18R and 2H,were successfully fabricated by laser powder bed fusion(LPBF).The remelting printing strat-egy with systematic optimization framework including densification and printability analysis was used to get optimal process window.The twin-related self-accommodation structure with long period stacking order substructure was formed during additive manufacturing process.The as-build samples show excel-lent mechanical properties(ultimate compressive strength of 1593±10 MPa and large fracture strain of 23.0%±0.1%)with double-yielding,and outstanding shape memory effect,with maximum recoverable strain of 3.39% and nearly 100%recovery rate under compressive strain not exceeding 6%.Furthermore,the microstructural evolution in LPBF involving remelting,martensitic transformation,and 2H marten-site was discussed.This result not only builds the microstructure framework involving high reflectivity alloys and martensitic transformation but also provides insight into the applicability of LPBF process in producing Cu-based SMAs. | Yankun Zhang Lianyong Xu Lei Zhao Danyang Lin Minqian Liu Xueyan Qi Yongdian Han | 2023 | Journal of Materials Science & Technology2023，，21： | 0 |
| 17 | An effective indoor radio map construction scheme based on crowdsourced samples显示文摘The crowdsourcing-based WLAN indoor localization system has been widely promoted for the effective reduction of the workload from the offline phase data collection while constructing radio maps.Aiming at the problem of the inaccurate location annotation of the crowdsourced samples,the existing invalid access points(APs)in collected samples,and the uneven sample distribution,as well as the diverse terminal devices,which will result in the construction of the wrong radio map,an effective WLAN indoor radio map construction scheme(WRMCS)is proposed based on crowdsourced samples.The WRMCS consists of 4 main modules:outlier detection,key AP selection,fingerprint interpolation,and terminal device calibration.Moreover,an online localization algorithm is put forward to estimate the position of the online test fingerprint.The simulation results show that the proposed scheme can achieve higher localization accuracy than the peer schemes,and possesses good effectiveness and robustness at the same time. | 郭若琳 Qin Danyang Zhao Min Xu Guangchao | 2020 | High Technology Letters2020，26，4： | 0 |
| 18 | Tuned single atom coordination structures mediated by polarization force and sulfur anions for photovoltaics显示文摘Impeding high temperature sintering is challengeable for synthesis of carbon-supported single-atom catalysts (C-SACs), which requires high-cost precursor and strictly-controlled procedures. Herein, by virtue of the ultrastrong polarity of salt melts, sintering of metal atoms is effectively suppressed. Meanwhile, doping with inorganic sulfur anions not only produces sufficient anchoring sites to achieve high loading of atomically dispersed Co up to 13.85 wt.%, but also enables their electronic and geometric structures to be well tuned. When served as a cathode catalyst in dye-sensitized solar cells, the C-SAC with Co-N4-S2 moieties exhibits high activity towards the iodide reduction reaction (IRR), achieving a higher power conversion efficiency than that of conventional Pt counterpart. Density function theory (DFT) calculations revealed that the superior IRR activity was ascribed to the unique structure of Co-N4-S2 moieties with lower reaction barriers and moderate binding energy of iodine on the Co center, which was beneficial to I2 dissociation. | Hongyu Jing Zhengyan Zhao Chunyang Zhang Wei Liu Danyang Wu Chao Zhu Ce Hao Jiangwei Zhang Yantao Shi | 2021 | Nano Research2021，14，11： | 0 |
| 19 | Microfluidic separation of particles by synergistic effect of geometry-induced hydrodynamics and magnetic field显示文摘Microfluidic combined with magnetic field have been demonstrated to be the promising solutions for fast and low-damage particles separation.However,the difficulties in the precise layout of magnets and accurate prediction of particle trajectories lead to under and over separation of target particles.A novel particle separation lab-on-chip(LOC)prototype integrated with microstructures and micropolar arrays is designed and characterized.Meanwhile,a numerical model for the separation of magnetic particles by the synergistic effect of geometry-induced hydrodynamics and magnetic field is constructed.The effect of geometry and magnetic field layout on particle deflection is systematically analyzed to implement accurate prediction of particle trajectories.It is found that the separation efficiency of magnetic particles increased from 50.2%to 91.7%and decreased from 88.6%to 85.7%in the range of depth factors from 15µm to 27µm and width factors from 30µm to 60µm,respectively.In particular,the combined effect of the offset distance of permanent magnets and the distance from the main flow channel exhibits a significant difference from the conventional perception.Finally,the developed LOC prototype was generalized for extension to arbitrary systems.This work provides a new insight and robust method for the microfluidic separation of magnetic particles. | Du Qiao Hongxia Li Weiping Zhu Lili Zhu Danyang Zhao Honglin Li | 2024 | Chinese Chemical Letters2024，35，2： | 0 |
| 20 | Epidemiology and control measures of an outbreak of neonatal echovirus 11 infections in Guangdong, China: A retrospective analysis显示文摘The objective of this study was to investigate the outbreak of echovirus 11 (ECHO 11) infection in newborns at a hospital in Guangdong Province, China, and to study the effectiveness of prevention and control measures to infer the epidemiological characteristics of ECHO 11 and explore the effective measures for its prevention and control. We performed retrospective analyses of hospital records and laboratory test data. In this outbreak, ten cases of ECHO 11 infection were identified, of which nine cases were nosocomial infections. Most of the cases (90%) were severe, and three died. The onset time interval of 10 patients was 1-4 days, most of which occur in 1-2 days. There were eight (80%) males and two females (20%). The gestational age of the patients was 31 to 40 weeks (mean, 35+4 weeks;median, 35+4 weeks). The onset time was 3-26 days (average 9 days;median 8 days). The birth weights of the patients ranged from 1,650 g to 3,450 g (mean 2,385 g;median 2,250 g). We concluded that neonatal infection with ECHO 11 will lead to serious symptoms and high mortality, and is prone to outbreaks of nosocomial infection. We speculate that ECHO 11 is most likely to spread via contact transmission;however, we do not rule out the possibility of droplet transmission. Prevention and control measures can effectively prevent and control hospital enteroviral infections. | Chunxiao Fang Xiaoming Zhang Xuemin Huang Fengqin Xu Danyang Zhao | 2023 | Biosafety and Health2023，5，4： | 0 |
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