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| 1 | Computing payment for ecosystem services in watersheds: An analysis of the Middle Route Project of South-to-North Water Diversion in China显示文摘Payment for ecosystem services (PES) has attracted considerable attention as an economic incentive for promoting natural resource management recently. As emphasis has been placed on using the incentive-based mechanism by the central government, rapid progress on PES research and practice has been achieved. However PES still faces many difficulties. A key issue is the lack of a fully-fledged theory and method to clearly define the design scope, accounting and feasibility of PES criteria. An improved watershed criteria model was developed in light of research on PES practices in China, investigations on the water source area for the Middle Route Project of South-to-North Water Diversion and ecosystem services outflows theory. The basic principle of assessment is the direct and opportunity cost for ecological conservation and environmental protection in the water source area deduct nationally-financed PES and internal effect. Then the scope and the criteria methods were determined, and internal effect was put forward to define benefits brought from water source area. Finally, Shiyan City, which is the main water source area for the Project of Water Diversion, was analyzed by this model and its payment was calculated. The results showed that: (1) during 2003-2050, the total direct cost and opportunity cost would reach up to 262.70 billion and 256.33 billion Chinese Yuan (CNY, 2000 constant prices), i.e., 50.61% and 49.38% of total cost, respectively; (2) Shiyan City would gain 0.23, 0.06 and 0.03 CNY/m3 in 2014-2020, 2021-2030, and 2031-2050, respectively. | Zhengju Dong Yan Yan Jing Duan Xiao Fu Qingrong Zhou Xiang Huang Xiangen Zhu Jingzhu Zhao | 2011 | Journal of Environmental Sciences2011，23，12： | 12 |
| 2 | Locomotor activity and anxiety status, but not spatial working memory,are affected in mice after brief exposure to cuprizone显示文摘Chronic long-term exposure to cuprizone causes severe brain demyelination in mice,which leads to changes in locomotion,working memory and anxiety.These findings suggest the importance of intact myelin for these behaviors.This study aimed to investigate the possible behavioral changes in mice with mild oligodendrocyte/myelin damage that parallels the white matter changes seen in the brains of patients with psychiatric disporders.We used the cuprizonetreated mouse model to test both tissue changes and behavioral functions(locomotor activity,anxiety status,and spatial working memory).The results showed that mice given cuprizone in their diet for 7 days had no significant myelin breakdown as evaluated by immunohistochemical staining for myelin basic protein,while the number of mature oligodendrocytes was reduced.The number and length of Caspr protein clusters,a structural marker of the node of Ranvier,did not change.The locomotor activity of the cuprizonetreated mice increased whereas their anxiety levels were lower than in normal controls;spatial working memory,however,did not change.These results,for the first time,link emotion-related behavior with mild white matter damage in cuprizone-treated mice. | Handi Zhang Yanbo Zhang Haiyun Xu Lingyan Wang Jinsong Zhao Junhui Wang Zhijun Zhang Qingrong Tan Jiming Kong Qingjun Huang Xin-Min Li | 2013 | Neuroscience Bulletin2013，29，5： | 4 |
| 3 | Phase diagrams of permanent magnet alloys: Binary rare earth alloy systems显示文摘Thermodynamic optimization of the binary rare earth alloy(Cee La, Cee Pr, Cee Nd and Lae Nd) systems was performed in this work through the CALPHAD method based on the critical evaluation of all available phase diagram and thermodynamic data reported in the literature. During the thermodynamic modeling, the solution phases including liquid, bcc, fcc and dhcp, were treated as the substitutional solution model. Thermodynamic parameters of the stable phases in the Cee La, Cee Pr, Cee Nd and Lae Nd binary systems are obtained finally and would be used directly to develop the thermodynamic database of the multi-component Nde Fee B-based alloys, which is indispensable for designing alloy compositions and processes of Nde Fee B permanent magnets with highly abundant rare earth metals. | Kaicheng Yang Jiang Wang Qingrong Yao Zhao Lu Maohua Rong Huaiying Zhou Guanghui Rao | 2019 | Journal of Rare Earths2019，37，10： | 3 |
| 4 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 5 | Testing the role of genetic variation of the MC4R gene in Chinese population in antipsychotic-induced metabolic disturbance显示文摘Antipsychotic-induced metabolic disturbance(AIMD) is a common adverse effect of antipsychotics with genetics partly underpinning variation in susceptibility among schizophrenia patients. Melanocortin4 receptor(MC4 R) gene, one of the candidate genes for AIMD, has been under-studied in the Chinese patients. We conducted a pharmacogenetic study in a large cohort of Chinese patients with schizophrenia. In this study, we investigated the genetic variation of MC4 R in Chinese population by genotyping two SNPs(rs489693 and rs17782313) in 1,991 Chinese patients and examined association of these variants with the metabolic effects that were often observed to be related to AIMD. Metabolic measures, including body mass index(BMI), waist circumference(WC), glucose, triglyceride, high-density lipoprotein(HDL), and low-density lipoprotein(LDL) levels were assessed at baseline and after 6-week antipsychotic treatment. We found that interaction of SNP×medication status(drug-na?ve/medicated) was significantly associated with BMI, WC, and HDL change %, respectively. Both SNPs were significantly associated with baseline BMI and WC in the medicated group. Moderate association of rs489693 with WC, Triglyceride, and HDL change % were observed in the whole sample. In the drug-na?ve group, we found recessive effects of rs489693 on BMI gain more than 7%, WC and Triglyceride change %, with AA incurring more metabolic adverse effects. In conclusion, the association between rs489693 and the metabolic measures is ubiquitous but moderate. Rs17782313 is less involved in AIMD. Two SNPs confer risk of AIMD to patients treated with different antipsychotics in a similar way. | Yamin Zhang Hongyan Ren Qiang Wang Wei Deng Weihua Yue Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Dai Zhang Liansheng Zhao Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Science China(Life Sciences)2019，62，4： | 3 |
| 6 | Interannual Variability and Scenarios Projection of Sea Ice in Bohai Sea Part Ⅰ: Variation Characteristics and Interannual Hindcast显示文摘The Bohai Sea is one of the southernmost areas for sea ice formation in the northern hemisphere.Sea ice disasters in this body of water severely affect marine activities and the safety of coastal residents.In this study,we analyze the variation characteristics of the sea ice in the Bohai Sea and establish an annual regression model based on predictable mode analysis method.The results show the following:1)From 1970 to 2018,the average ice grade is(2.6±0.8),with a maximum of 4.5 and a minimum of 1.0.Liaodong Bay(LDB)has the heaviest ice conditions in the Bohai Sea,followed by Bohai Bay(BHB)and Laizhou Bay(LZB).Interannual variation is obvious in all three bays,but the linear decreasing trend is significant only in BHB.2)Three modes are obtained from empirical orthogonal function analysis,namely,single polarity mode with the same sign of anomaly in all of the three bays and strong interannual variability(82.0%),the north–south dipole mode with BHB and LZB showing an opposite sign of anomalies to that in LDB and strong decadal variations(14.5%),and a linear trend mode(3.5%).Critical factors are analyzed and regression equations are established for all the principal components,and then an annual hindcast model is established by synthesizing the results of the three modes.This model provides an annual spatial prediction of the sea ice in the Bohai Sea for the first time,and meets the demand of operational sea ice forecasting. | JIAO Yan HUANG Fei LIU Qingrong LI Ge LI Yaru YU Qingxi ZHAO Yiding | 2020 | Journal of Ocean University of China2020，19，2： | 2 |
| 7 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022，37，5： | 2 |
| 8 | Characterization of corroded bronze Ding from the Yin Ruins of China 显示文摘 | He Ling Zhao Qingrong | 2007 | Corrosion Science2007，49，： | 1 |
| 9 | Electron beam irradiation modification of collagen membrane显示文摘 | Bo Jiang Zhihong Wu Huichuan Zhao Fangyuan Tang Jian Lu Qingrong Wei Xingdong Zhang | 2005 | Biomaterials2005，，： | 1 |
| 10 | Molecular Characterization of Drug-Resistant Mycobacterium tuberculosis Isolates from Sichuan Province in China 显示文摘 | Guo Jianhua Xiang Wenliang Zhao Qingrong | 2008 | Jpn J Infect Dis2008，6，： | 1 |
| 11 | Microstructural regulation,oxidation resistance,and mechanical properties of C_(f)/SiC/SiHfBOC composites prepared by chemical vapor infiltration with precursor infiltration pyrolysis显示文摘To further improve the oxidation resistance of polymer derived ceramic(PDC)composites in harsh environments,Cf/SiC/SiHfBOC composites were prepared by chemical vapor infiltration(CVI)and precursor impregnation pyrolysis(PIP)methods.The weight retention change,mechanical properties,and microstructure of C/SiC/SiHfBOC before and after oxidation in air were studied in details.Microscopic analyses showed that only the interface between the ceramics and fibers was oxidized to some extent,and hafnium had been enriched on the composite surface after oxidizing at different temperature.The main oxidation products of Cf/SiC/SiHfBOC composites were Hf0_(2)and HfSi04 after oxidation at 1500℃for 60 min.Moreover,the weight retention ratio and compressive strength of the Cf/SiC/SiHfBOC composites are 83.97%and 23.88±3.11 MPa,respectively.It indicates that the Cf/SiC/SiHfBOC composites should be promising to be used for a short time in the oxidation environment at 1500℃. | Yang LYU Baihe DU Guiqing CHEN Guangdong ZHAO Yuan CHENG Shanbao ZHOU Qingrong LV Xinghong ZHANG Wenbo HAN | 2022 | Journal of Advanced Ceramics2022，11，1： | 1 |
| 12 | Characterization of Corroded bronze Ding from the Yin Ruins of China 显示文摘 | He Ling Zhao Qingrong Gao Min | 2007 | Corrosion Science2007，49，6： | 1 |
| 13 | Adsorption equilibrium and the effect of honeycomb heat exchanging device on charge/discharge characteristic of methane on MIL-101(Cr)and activated carbon显示文摘Experiments were conducted for developing suitable ANG adsorbents for vehicular applications.MIL-101 and activated carbon samples were respectively prepared by hydrothermal and chemical activation methods.Two samples were undergone structure analysis on adsorption data of nitrogen at 77.15 K,and adsorption data of methane were then volumetrically measured within temperature-pressure range 293.15 K-313.15 K and 0-8 MPa.A conformable vessel in volume 2.5 L was employed for charge/discharge tests under the flow rate 10-30 L·min^-1.It shows that limit isostreic heat of methane adsorption is respectively about 25.15 k J·mol^-1 and22.94 k J·mol^-1 on the activated carbon and the MIL-101,and isosteric heat within the experimental condition is 14-19.5 k J·mol^-1;employing a smaller charge/discharge flow rate can weaken the temperature fluctuation of the adsorbent bed and increase the charge/discharge amount;employing honeycomb heat exchanging device enhance the thermal conductivity of the adsorbent bed by consuming a negligible part of volume of the vessel.It suggests that a smaller flow rate for charge/discharge should be employed,and MOFs together with the honeycomb heat exchanging device are promising for practical applications. | Guobin Zhao Qingrong Zheng Xuan Zhang Weidong Zhang | 2020 | Chinese Journal of Chemical Engineering2020，28，7： | 1 |
| 14 | Behavioral problems and related factors in children of different aged patients with schizophrenia: A cross-sectional study显示文摘BACKGROUND:With the age growing,changes of behavioral problems in children whose parents had schizophrenia,differences of related factors and ways for particular intervention should be further studied. OBJECTIVE:To survey the behavioral problems in children of different aged patients with chizophrenia and investigate the correlation between behavioral problems and related factors in different aged groups. DESIGN:Cross-sectional study. SETTING:Shandong Mental Health Center. PARTICIPANTS:A total of 364 patients with schizophrenia were selected from eleven psychiatric hospitals from June 1999 to June 2000. There were 179 males and 185 females,and their ages ranged from 28 to 45 years. All patients met modified diagnostic criteria of schizophrenia(the second edition),China Classification of Mental Diseases and Diagnostic Criteria. Meanwhile,children of the 364 patients were grouped based on their ages,including 6-11 years old group [n =217;114 males and 103 females;mean age of(9±2) years] and 12-16 years old group [n =147;99 males and 48 females;mean age of(14± 1) years]. The Chinese norms of Achenbach's Child Behavior Check List were regarded as the normal control group. METHODS:Children who received self-made mental health related factors inventory and Achenbach's Child Behavior Check List were involved in this study. All children and their parents provided the confirmed consent. Achenbach's Child Behavior Check List was used for parents to mainly evaluate children,and the results manifested various behavioral problems based on different sexes and different ages. Self-made mental health related factors inventory contained questionnaires for parents and children,respectively. In this study,home situation of parents as well as personality characteristics and educational styles of children were mainly evaluated. MAIN OUTCOME MEASURES:① Scores of Achenbach's Child Behavior Check List in different aged children;② Scores of self-made mental health related factors inventory based on different home situations and educational styles. RESULTS:Children of 364 patients were involved in the final analysis. ① There were no significant differences in total score of Achenbach's Child Behavior Check List and sex in the two groups(P > 0.05). There were significant differences in schizoid,body recount,aggression,depression,hyperactivity,violating discipline,compulsion and total abnormal rate of boys between the 6-11 years old group and the normal control group(P < 0.05-0.01). In addition,there were also significant differences in poor communication,depression,hyperactivity,violating discipline,compulsion and total abnormal rate of girls between the 6-11 years old group and the normal control group(P < 0.05-0.01). ② As compared with normal control group,scores of home environment in the two aged groups demonstrated that educational level was low;interpersonal relationship was poor;relation to children was not closed;relationship between husband and wife was not harmonious;positive rate of family history was high;economic status was poor;family atmosphere was poor. Therefore,there was significant difference(P < 0.01). Educational level in parental generation and single parent family in the 6-11 years old group were higher than that in the 12-16 years old group,with significant difference(P < 0.05). As compared with the normal control group,results of education demonstrated that children in the two aged groups had poor communication with other children;they had poor behaviors in schools;most of them were boarded and had poor relationship with their parents;teaching styles for children were different. CONCLUSION:All children of different aged patients with schizophrenia had poor home environment and education;and they were often affected by other factors. Behavioral problems were changed with the age growing;in addition,these changes were related to home environment,education and society. Therefore,comprehensive intervention may be an ideal method. | Huimin Qiu Guifang Zhao Yangu Wang Mingyou Chen Jintong Liu Jisheng Tang Aijun Cui Yuying Zheng Chengyou Zhu Ping Li Shansong Wang Chengyong Sun Xueyun Qiao Wei Zhang Shengang Song Qingrong Li | 2007 | Neural Regeneration Research2007，2，11： | 0 |
| 15 | Design and fabrication of self-suspending aluminum-plastic/semiconductor photocatalyst devices for solar energy conversion显示文摘The design and synthesis of self-suspending photocatalyst device with easy recyclability is important for practical application.Here,this work utilizes aluminum-plastic package waste as raw material to prepare an aluminum-plastic supported TiO_(2)(AP-TiO_(2))photocatalyst device through 3D printing design and surface deposition method.A series of characterizations were carried out to explore the structure,morphology and performance of the AP-TiO_(2)device.Under UV light illumination,the AP-TiO_(2)-50 efficiently degrade 93.6%tetracycline hydrochloride(THC)after 4 hr,which increases by 8.3%compared with that of TiO_(2)powder suspension system with the same catalyst amount.Based on it,AP-ZnO,AP-CdS,AP-g-C_3N_4and AP-Pt-TiO_(2)are also fabricated,and applied in photocatalytic degradation and hydrogen evolution,which all exhibit higher photoactivities than powder suspension systems.This work provides a new avenue for the fabrication of advanced recyclable photocatalyst device.Moreover,the work offers a novel sight for the high-value utilization of aluminum-plastic package waste,which has positive implications for environmental protection. | Zhi-Ang Zhao Jingyun Mao Chengjing Lu Shuangqiao Yang Qingrong Qian Qinghua Chen Hun Xue Xiaoli Sun Min-Quan Yang | 2024 | Journal of Environmental Sciences2024，，2： | 0 |
| 16 | 5-Demethylnobiletin and its major metabolites:efficient preparation and mechanism of their anti-proliferation activity in HepG2 cells显示文摘5-Demethylnobile tin(5-DMN),a hydroxylated polymethoxyflavone(OH-PMF)identified in aged citrus peels,has demonstrated health benefiting effects in previous studies.5-DMN undergoes biotransformation in vivo,yielding 5,3’-didemethylnobiletin(5,3’-DDMN),5,4’-didemethylnobiletin(5,4’-DDMN)and5,3’,4’-tridemethylnobiletin(5,3’,4’-TDMN).However,the anti-cancer effects of 5-DMN and its in vivo metabolites against HepG2 cells remain unclear.In this study,an efficient chemical synthetic method was developed to obtain 5-DMN and its 3 metabolites,and their molecular structures were confirmed by;H NMR and LC-MS.Cytotoxicity,cell cycle arrestment,apoptosis and caspase-3 expression were investigated to evaluate the anti-liver cancer effects of these OH-PMFs on HepG2 cells.The results showed that all 4 compounds inhibited the proliferation of HepG2 cells in a concentration-dependent manner.Their anti-proliferative activity was exerted through inducing G2/M phase arrestment,cell apoptosis and promoting expression of a key apoptotic protein called cleaved caspase-3.Our results indicated that 5,3’-DDMN and5,3’,4’-TDMN showed a stronger inhibitory activity on cell proliferation than 5-DMN,followed by 5,4’-DDMN.The expression of cleaved caspase-3 was the highest in cells treated with 5,4’-DDMN,implying that the apoptosis induced by other OH-PMFs might be mediated by other apoptotic execution proteins.Our research reveals the application potential and scientific evidence for the production and functionality of OH-PMFs. | Yanping Xin Ting Zheng Man Zhang Ruiqiang Zhang Siyue Zhu Dongli Li Denggao Zhao Yanyan Ma Chi-Tang Ho Qingrong Huang | 2022 | Food Science and Human Wellness2022，11，5： | 0 |
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