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| 1 | High-performance planar heterojunction perovskite solar cells: Preserving long charge carrier diffusion lengths and interracial engineering显示文摘 | Sai Bai Zhongwei Wu Xiaojing Wu Yizheng Jin Ni Zhao Zhihui Chen Qingqing Mei Xin Wang Zhizhen Ye Tao Song Ruiyuan Liu Shuit-tong Lee Baoquan Sun | 2014 | Nano Research2014，7，12： | 13 |
| 2 | Generation of seed lipoxygenase-free soybean using CRISPR-Cas9显示文摘Beany flavor induced by three lipoxygenases(LOXs, including LOX1, LOX2, and LOX3)restricts human consumption of soybean. It is desirable to generate lipoxygenase-free new mutant lines to improve the eating quality of soybean oil and protein products. In this study, a pooled clustered regularly interspaced short palindromic repeats(CRISPR)-CRISPRassociated protein 9(Cas9) strategy targeting three GmLox genes(GmLox1, GmLox2, and GmLox3) was applied and 60 T_0 positive transgenic plants were generated, carrying combinations of sg RNAs and mutations. Among them, GmLox-28 and GmLox-60 were gmlox1 gmlox2 gmlox3 triple mutants and GmLox-40 was a gmlox1 gmlox2 double mutant.Sequencing of T_1 mutant plants derived from GmLox-28, GmLox-60, and GmLox-40 showed that mutation in the GmLox gene was inherited by the next generation. Colorimetric assay revealed that plants carrying different combinations of mutations lost the corresponding lipoxygenase activities. Transgene-free mutants were obtained by screening the T_2 generation of lipoxygenase-free mutant lines(GmLox-28 and GmLox-60). These transgeneand lipoxygenase-free mutants could be used for soybean beany flavor reduction without restriction by regulatory frameworks governing transgenic organisms. | Jie Wang Huaqin Kuang Zhihui Zhang Yongqing Yang Long Yan Mengchen Zhang Shikui Song Yuefeng Guan | 2020 | The Crop Journal2020，8，3： | 9 |
| 3 | Bionic Coupling of Hardness Gradient to Surface Texture for Improved Anti-wear Properties显示文摘 | Long Zheng Jianjun Wu Si Zhang Shishuai Sun Zhihui Zhang Song Liang Zhenning Liu Luquan Ren | 2016 | Journal of Bionic Engineering2016，13，3： | 9 |
| 4 | MicroRNA-638 inhibits cell proliferation by targeting phospholipase D1 in human gastric carcinoma显示文摘MicroRNAs (miRNAs ) 是经常是玩的小非编码的 RNA 的一种类型在 carcinogenesis 的重要角色,而是 miRNAs 的 carcinogenic 机制仍然是不清楚的。这研究将在癌(GC ) 调查功能和 miR-638 的机制。在 GC 和 miR-638 的 DNA 拷贝数字的 miR-638 的表示被即时 PCR 检测。房间增长上的 miR-638 的效果被数 kit-8 试金测量。不同试金,包括生物信息学算法(TargetScan 并且人权保护) ,酶报告试金并且西方的弄污,被用来在 GC 识别 miR-638 的目标基因。在临床的 CRC 纸巾的 miR-638 目标基因的表示被 immunohistochemical 试金也验证。从这研究,我们发现 miR-638 与相应 noncancerous 纸巾(NCT ) 相比是在 GC 纸巾的 downregulated,并且 miR-638 的 DNA 拷贝数字比 NCT 在 GC 是更低的,它可以在 GC 导致 miR-638 的相应 downregulation。miR-638 的宫外的表示在 vitro 禁止了 GC 细胞生长。随后,我们鉴别 PLD1 是在 GC,和 silencing PLD1 表示 phenocopied 的 miR-638 的目标基因 GC 房间增长上的 miR-638 的禁止的效果。而且,我们观察到 PLD1 是在在预言的 GC 的 PLD1 的 GC 纸巾,和高表示的 overexpressed 差的全面幸存。在摘要,我们表明 miR-638 通过禁止 PLD1 在 GC 作为肿瘤 suppressor 工作。 | Jiwei Zhang Zehua Bian Jialiang Zhou Mingxu Song Zhihui Liu Yuyang Feng Li Zhe Binbin Zhang Yuan Yin Zhaohui Huang | 2015 | Protein & Cell2015，6，9： | 8 |
| 5 | Adsorption-energy-based activity descriptors for electrocatalysts in energy storage applications显示文摘Energy storage technologies, such as fuel cells, ammonia production and lithium–air batteries, are important strategies for addressing the global challenge of energy crisis and environmental pollution.Taking overpotential as a direct criterion, we illustrate in theory and experiment that the adsorption energies of charged species such as Li^++e^-and H^++e^-are a central parameter to describe catalytic activities related to electricity-in/electricity-out efficiencies. The essence of catalytic activity is revealed to relate with electronic coupling between catalysts and charged species. Based on adsorption energy, some activity descriptors such as d-band center, e_g-electron number and charge-transfer capacity are further defined by electronic properties of catalysts that directly affect interaction between catalysts and charged species. The present review is helpful for understanding the catalytic mechanisms of these electrocatalytic reactions and developing accurate catalytic descriptors, which can be employed to screen high-activity catalysts in future high-throughput calculations and experiments. | Youwei Wang Wujie Qiu Erhong Song Feng Gu Zhihui Zheng Xiaolin Zhao Yingqin Zhao Jianjun Liu Wenqing Zhang | 2018 | National Science Review2018，5，3： | 8 |
| 6 | Estimation of tree transpiration and response of tree conductance to meteorological variables in desert-oasis system of Northwest China显示文摘Transpirations of three dominated tree species, namely Mongol Scotch Pine (Pinus sylvestris var. mongolica Litvin), White elm (Ulmus pumila) and Gansu Poplar (Populus gansuensis Wang et Yang) in oasis shelter forest (Linze site) and of two dominated tree species,namely Euphrates Poplar (Populus euphratica Oliv.) and Russia olive (Elaeagnus angustifolia Linn.) in lowland desert (Erjinaqi site) have been estimated using measured sapflow in summer,autumn and winter, 2002 and in spring, 2003. An ENVIS System was used for each site to measure microclimate variables, soil moisture and sapflow every half an hour, and the study time scale is one day. In the 104 days of observation during the growing season at the Linze site, the average daily sapflow of Gansu Poplar is 9.93L·d-1,and the average transpiration per unit leaf area is 1.99mm·d-1.For White elm tree,the daily average sapflow is 4.08L·d-1,while the daily average transpiration per unit leaf area is 0.49mm·d-1.The values for Mongol Scotch Pine are 3.91L·d-1 and 0.25mm·d-1,respectively.In the total 73 days of observation during the growing season at the Erjinaqi site, the daily average sapflows of Russia olive and Euphrates Poplar are 12.1 and 20.97L·d-1,respectively,and the average transpirations per unit leaf area are 0.22 amd 0.31mm·d-1,respectively.In the observation period of the growing season,tree conductances of Mongol Scotch Pine, White elm, Gansu Poplar or Russia olive show an exponential relationship with the daily average air temperature or vapour pressure deficit, but the relationship is not so obvious between tree conductance and global radiation. The transpiration process of each tree species is affected by all the observed four environmental variables. The response of tree conductance to different climatic factors changes with tree species. The effect of the same factor to the same tree species is also variable in different growing stages. The sapflow of every tree species is relatively large in later spring to early summer, and low in summer, and then reaches its largest value in later September. In the mid-November, the sapflow is relatively large, especially the deciduous tree species. This may be characteristic of the tree species in Arid Regions of Northwest China. | CHEN Rensheng KANG Ersi ZHANG Zhihui ZHAO Wenzhi SONG Kechao ZHANG Jishi LAN Yongchao | 2004 | Science China Earth Sciences2004，47，z1： | 5 |
| 7 | The Bethesda System for Reporting Thyroid Cytopathology(TBSRTC):A report of 2,781 cases in a Chinese population显示文摘Objective:To evaluate the diagnostic utility of The Bethesda System for Reporting Thyroid Cytology(TBSRTC)at Peking University Cancer Hospital,the incidence of noninvasive follicular thyroid neoplasms with papillary-like nuclear features(NIFTP),and the impact of reclassification on cytopathological outcomes.Methods:We performed a retrospective study of thyroid fine-needle aspiration(FNA)cases between April 2014 and March 2019.The FNA results were classified according to TBSRTC.Post-surgery histological findings were followed up.Results:A total of 2,781 thyroid FNAs were performed.The incidences of the 6 diagnostic categories(DCs I-VI)were 14.8%,17.1%,15.8%,2.3%,11.6%and 38.5%,respectively.A total of 1,122 patients(40.3%)had corresponding histological results.NIFTP accounted for 0.4%of papillary thyroid carcinoma(PTC)cases,and there was no significant difference in the risk of malignancy(ROM)for each TBSRTC DC between'NIFTP=carcinoma(Ca)'and'NIFTP≠Ca'.When'NIFTP=Ca',the sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),and accuracy of TBSRTC were 98.0%,84.0%,99.4%,58.3%,and97.5%,respectively.When'NIFTP≠Ca',the sensitivity,specificity,PPV,NPV and accuracy of the TBSRTC were 98.1%,81.5%,99.3%,61.1%,and 97.5%,respectively.Conclusions:TBSRTC is effective in the preoperative diagnosis of thyroid nodules in Peking University Cancer Hospital.The impact of the reclassification of NIFTP on cytopathological outcomes is limited because of its low incidence,and the revised ROMs are not suitable for Asian patients. | Yanli Zhu Yuntao Song Guohui Xu Zhihui Fan Wenhao Ren | 2020 | Chinese Journal of Cancer Research2020，32，2： | 4 |
| 8 | Ectopic expression of VRT-A2 underlies the origin of Triticum polonicum and Triticum petropavlovskyi with long outer glumes and grains显示文摘Polish wheat (Triticum polonicum) is a unique tetraploid wheat species characterized by an elongated outer glume. The genetic control of the long-glume trait by a single semi-dominant locus, P1 (from Polish wheat), was established more than 100 years ago, but the underlying causal gene and molecular nature remain elusive. Here, we report the isolation of VRT-A2, encoding an SVP-clade MADS-box transcription factor, as the P1 candidate gene. Genetic evidence suggests that in T. polonicum, a naturally occurring sequence rearrangement in the intron-1 region of VRT-A2 leads to ectopic expression of VRT-A2 in floral organs where the long-glume phenotype appears. Interestingly, we found that the intron-1 region is a key ON/OFF molecular switch for VRT-A2 expression, not only because it recruits transcriptional repressors, but also because it confers intron-mediated transcriptional enhancement. Genotypic analyses using wheat accessions indicated that the P1 locus is likely derived from a single natural mutation in tetraploid wheat, which was subsequently inherited by hexaploid T. petropavlovskyi. Taken together, our findings highlight the promoter-proximal intron variation as a molecular basis for phenotypic differentiation, and thus species formation in Triticum plants. | Jing Liu Zhaoyan Chen Zhihui Wang Zhaoheng Zhang Xiaoming Xie Zihao Wang Lingling Chai Long Song Xuejiao Cheng Man Feng Xiaobo Wang Yanhong Liu Zhaorong Hu Jiewen Xing Zhenqi Su Huiru Peng Mingming Xin Yingyin Yao Weilong Guo Qixin Sun Jie Liu Zhongfu Ni | 2021 | Molecular Plant2021，14，9： | 4 |
| 9 | Development of High Sensitivity Eight-Element Multiplexed Fiber Laser Acoustic Pressure Hydrophone Array and Interrogation System显示文摘纤维激光水中听音器由于唯一的优点和宽广申请前景得到了普遍担心。在这篇论文,研究八元素的多路的纤维激光结果声学的压力数组和讯问系统被介绍,包含的低噪音的分布式的反馈纤维激光(DFB-FL ) 制造,包装的敏感改进,和 interferometric 表明解调。系统的频率反应范围是 10Hz-10kHz,声学的压力敏感到达的激光频率 115 dB re Hz/Pa,和声学的压力是的相等的噪音不到 60Pa/Hz 1/2 。系统的动态范围比 120 dB 大。 | Ming LI Zhihui SUN Xiaolei ZHANG Shujuan LI Zhiqiang SONG Meng WANG Jian GUO Jiasheng NI Chang WANG Gangding PENG Xiangang XU | 2017 | Photonic Sensors2017，7，3： | 4 |
| 10 | Spatial structure and seasonal changes of nekton assemblages in the Taiwan Strait显示文摘The Taiwan Strait is a transition zone between the East China Sea and the South China Sea with unique hydrology and a geographical environment that creates special marine community features.To analyze the spatial structure and seasonal changes of the nekton assemblages in the Taiwan Strait,seasonal experimental trawl surveys were conducted during 2006–2007.The results showed that there were two assemblages in the area with different sets of species,and the average similarity within each group varies between 39.38% and 74.20%.By using multivariate statistical analysis and analyzing the distribution of dominant species,we found that the structures of the assemblages had obvious seasonal variation.The middle region from the Putian transect to the Xiamen transect could be considered a mixing area for the two assemblages.The analysis of the relationship between species assemblages and environmental factors indicated that temperature was the most important factor affecting the community structure in cold seasons,and 22.5°C and 17°C could be considered dividing lines for spring and winter,respectively.In warm seasons,the most important factor was water depth,but the relationship with depth was not as significant,with a correlation between 0.264 and 0.399.The seasonal changes of nekton assemblages basically reflected the dynamic currents in the Taiwan Strait.The south coastal assemblage extended to nearly the entire area of the Taiwan Strait along with a strong and intense warm current that shrinks in spring and winter when the southward intrusion of the cold Zhejiang-Fujian coastal current becomes stronger.The impact of shortterm and long-term environmental changes,such as extreme weather,global warming and human activity on nekton assemblages,had been recognized but need further research.Our study on nekton assemblages could be used as a baseline for measuring future changes. | SONG Puqing LIN Longshan LI Yuan ZHONG Zhihui | 2016 | Acta Oceanologica Sinica2016，35，6： | 3 |
| 11 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells显示文摘 | Miguel Angel Esteban Tao Wang Baoming Qin Jiayin Yang Dajiang Qin Jinglei Cai Wen Li Zhihui Weng Jiekai Chen Su Ni Keshi Chen Yuan Li Xiaopeng Liu Jianyong Xu Shiqiang Zhang Feng Li Wenzhi He Krystyna Labuda Yancheng Song Anja Peterbauer Susanne Wolbank H | 2010 | Cell Stem Cell2010，，： | 3 |
| 12 | Highly efficient fluoride removal from water using 2D metal-organic frameworks MIL-53(Al)with rich Al and O adsorptive centers显示文摘In this study,metal-organic framework MIL-53(Al)was synthesized and studied to understand the different mechanisms between normal MIL-53(Al)and 2D metal-organic framework MIL-53(Al)for removing fluoride.Comparatively,the 2D MIL-53(Al)had two-dimensional linear morphology rather than block shape,indicating more expose adsorptive sites than normal MIL-53(Al).The batch adsorption experiments were applied to investigate the performance of 2D MIL-53(Al),including pH,adsorption kinetics,and thermodynamics.The 2D MIL-53(Al)(75.50 mg/g)showed better adsorption capacity than normal MIL-53(Al)(35.63 mg/g).The adsorption process of 2D MIL-53(Al)followed the pseudo-firstorder model and Langmuir model.The adsorption mechanism of this material was further studied by using experimental characterization and density functional theory calculations in detail.The main adsorptive sites were Al and O in the 2D MIL-53(Al),and the relationship between fluoride binding with Al and O was HF^(-)_(2)>HF>F^(-).The species of fluoride were HF2,HF,F at different pH and concentrations.Hence,this study provides a significant way on the application of two-dimensional materials for removing fluoride. | Lei Huang Zhihui Yang Sikpaam Issaka Alhassan Zhixuan Luo Baocheng Song Linfeng Jin Yixian Zhao Haiying Wang | 2021 | Environmental Science and Ecotechnology2021，，4： | 3 |
| 13 | Control of phase,polarization,and amplitude based on geometric phase in a racemic helix array显示文摘The Pancharatnam–Berry geometric phase has attracted great interest due to the elegant phase control strategy via geometric transformation of optical elements.The commonly used geometric phase is associated with circular polarization states.Here,we show that by exploiting the geometric phase associated with the two elliptical eigenpolarization states in a racemic metallic helix array,exotic features including full range phase modulation for linear polarization states,diverse polarization conversion,and full complex amplitude modulation can be obtained with rotation of the helices.As a proof of concept,several devices for implementing polarization conversion,vortex beam generating,and lateral dual focusing are built with a racemic helix array in the microwave regime.The calculated and experimental results validate our proposals,which can stimulate various advanced metadevices. | CHAO WU QUAN LI ZHIHUI ZHANG SONG ZHAO HONGQIANG LI | 2021 | Photonics Research2021，9，11： | 2 |
| 14 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells显示文摘 | Miguel Angel Esteban Tao Wang Baoming Qin Jiayin Yang Dajiang Qin Jinglei Cai Wen Li Zhihui Weng Jiekai Chen Su Ni Keshi Chen Yuan Li Xiaopeng Liu Jianyong Xu Shiqiang Zhang Feng Li Wenzhi He Krystyna Labuda Yancheng Song Anja Peterbauer Susanne Wolbank H | 2010 | Cell Stem Cell2010，，1： | 1 |
| 15 | The optimal information rate for graph access structures of nine participants显示文摘 | Yun SONG Zhihui LI Yongming LI Ren XIN | 2015 | Frontiers of Computer Science2015，9，5： | 1 |
| 16 | RAF22,ABI1 and OST1 form a dynamic interactive network that optimizes plant growth and responses to drought stress in Arabidopsis显示文摘Plants adapt to their ever-changing environment via positive and negative signals induced by environmental stimuli.Drought stress,for instance,induces accumulation of the plant hormone abscisic acid(ABA),triggering ABA signal transduction.However,the molecular mechanisms for switching between plant growth promotion and stress response remain poorly understood.Here we report that RAF(rapidly accelerated fibrosarcoma)-LIKE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 22(RAF22)in Arabidopsis tha/iana physically interacts with ABA INSENSITIVE 1(ABl1)and phosphorylates ABl1 at Ser416 residue to enhance its phosphatase activity.Interestingly,ABl1 can also enhance the activity of RAF22 through dephosphorylation,reciprocally inhibiting ABA signaling and promoting the maintenance of plant growth under normal conditions.Under drought stress,however,the ASA-activated OPEN STOMATA1(OST1)phosphorylates the Ser81 residue of RAF22 and inhibits its kinase activity,restraining its enhancement of ABl1 activity.Taken together,our study reveals that RAF22,ABl1,and OST1 form a dynamic regulatory network that plays crucial roles in optimizing plant growth and environmental adaptation under drought stress. | Zhihui Sun Zhenkai Feng Yanglin Ding Yuanpeng Qi Shan Jiang Zhen Li Yu Wang Junsheng Qi Chunpeng Song Shuhua Yang Zhizhong Gong | 2022 | Molecular Plant2022，15，7： | 1 |
| 17 | Organocatalytic Stereoselective Synthesis of 3-Alkyl-3-hydroxy-2-oxindoles Catalyzed by Novel Water-compatible Axially Unfixed Biaryl-based Bifunctional Organocatalysts显示文摘In this work,six novel axially unfixed biaryl-based water-compatible bifunctional organocatalysts were de-signed and synthesized for the organocatalytic access to a variety of 3-alkyl-3-hydroxy-2-oxindole derivatives via aldol reactions in water.Organocatalyzed by 5a,the direct aldol reactions of isatins with enolisable ketones under-went readily in water,furnishing the structurally diverse 3-alkyl-3-hydroxy-2-oxindoles in various stereoselectivi-ties(up to>99%dr and>99%ee).Moreover,a plausible transition state of the conducted aldol reactions was hy-pothesized to shed light on the observed stereoselectivities of the obtained 3-alkyl-3-hydroxy-2-oxindoles. | Hongwu Zhao Wei Meng Zhao Yang Ting Tian Zhihui Sheng Hailong Li Xiuqing Song Yutong Zhang Sen Yang Bo Li | 2014 | Chinese Journal of Chemistry2014，32，5： | 1 |
| 18 | Proton Pump Inhibitors and the Risk of Colorectal Cancer显示文摘 | Shicai Chen Xinming Song Xiang Gao Mingzhe Li Zhihui Chen Yulong He Wenhua Zhan | 2011 | Journal of Clinical Gastroenterology2011，，2： | 1 |
| 19 | Synthesis and Properties of PGS-Li Scaffold显示文摘 | LIU Zhihui LU Yadong FENG Wei YANG Junxing GAO Shang SONG Lijie WANG Yao WANG Bowei | 2018 | Chemical Research in Chinese Universities2018，34，4： | 1 |
| 20 | Fuzzy intelligent control method for improving flight attitude stability of plant protection quadrotor UAV显示文摘At present,the attitude control method of plant protection UAV is the classical PID control,but there are some imperfections in the PID control,such as the contradiction between speediness and overshoot,the weak anti-jamming ability and adaptability.The physical parameters of plant protection UAV are time-varying,and the airflow also interferes with it.The control ability of classical PID is limited,and its control parameters are fixed,and its anti-jamming ability and adaptability are not strong.Therefore,a fuzzy adaptive PID controller is proposed in this paper.Fuzzy logic control is used to optimize the control parameters of PID in order to improve the dynamic and static performance and adaptability of attitude control of plant protection UAV.In the process of research,the mathematical model of UAV is established firstly,then the fuzzy adaptive PID is designed,and then the simulation is carried out in Simulink.The simulation results show that the fuzzy adaptive PID controller has better dynamic and static control performance and adaptability than the traditional PID controller.Therefore,the proposed control method has excellent application value in the attitude of plant protection UAV. | Zhihui He Wanlin Gao Xiongkui He Minjuan Wang Yunling Liu Yue Song Zewu An | 2019 | International Journal of Agricultural and Biological Engineering2019，12，6： | 1 |
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