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| 1 | RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings显示文摘在有前列腺癌症的不同赛跑的病人之中有显著不同;然而,位于这差别下面的机制仍然保持不清楚。这里,我们在场 transcriptome 的一处全面风景用 RNA-seq,越过关于基因熔化的前列腺癌症 transcriptomes 的揭示巨大的差异,长 noncoding RNA (长 ncRNA ) ,其他的拼接和体的变化从中国人口 14 主要前列腺癌症和他们的配对的正常对应物介绍。14 个肿瘤(21.4%) 中的三个在中国病人怀有 TMPRSS2 尔格熔化,和这熔化的低流行进一步在一个另外的肿瘤集合(10/54=18.5%) 被证实。尤其是,二新奇基因熔化, CTAGE5-KHDRBS3 (20/54=37%) 和 USP9Y-TTTY15 (19/54=35.2%) ,在我们的耐心的队经常发生了。介绍的进一步系统的 transcriptional 识别了是在肿瘤表示的差别的众多的长 ncRNAs。在长 ncRNA 和基因的表示之间的关联的分析建议长 ncRNAs 可以在 transcriptional 规定以外有功能。这研究在中国人口产出新卓见进前列腺癌症的致病。 | Shancheng Ren Zhiyu Peng Jian-Hua Mao Yongwei Yu Changjun Yin Xin Gao Zilian Cui Jibin Zhang Kang Yi Weidong Xu Chao Chen Fubo Wang Xinwu Guo Ji Lu Jun Yang Min Wei Zhijian Tian Yinghui Guan Liang Tang Chuanliang Xu Linhui Wang Xu Gao Wei Tian Jian Wang Huanming Yang Jun Wang Yinghao Sun | 2012 | Cell Research2012，22，5： | 66 |
| 2 | (La0.2Ce0.2Nd0.2Sm0.2Eu0.2)2Zr2O7:A novel high-entropy ceramic with low thermal conductivity and sluggish grain growth rate显示文摘Fine grains and slow grain growth rate are beneficial to preventing the thermal stress-induced cracking and thermal conductivity increase of thermal barrier coatings.Inspired by the sluggish diffusion effect of high-entropy materials,a novel high-entropy(HE)rare-earth zirconate solid solution(La0.2Ce0.2Nd0.2Sm0.2Eu0.2)2 Zr2 O7 was designed and successfully synthesized in this work.The as-synthesized(La0.2Ce0.2Nd0.2Sm0.2Eu0.2)2 Zr2 O7 is phase-pure with homogeneous rare-earth element distribution.The thermal conductivity of as-synthesized(La0.2Ce0.2Nd0.2Sm0.2Eu0.2)2 Zr2 O7 at room temperature is as low as 0.76 W m^-1 K^-1.Moreover,after being heated at 1500℃for 1-18 h,the average grain size of(La0.2Ce0.2Nd0.2Sm0.2Eu0.2)2 Zr2 O7 only increases from 1.69μm to 3.92μm,while the average grain size of La2Zr2O7 increases from 1.96μm to 8.89μm.Low thermal conductivity and sluggish grain growth rate indicate that high-entropy(La0.2Ce0.2Nd0.2Sm0.2Eu0.2)2Zr2O7 is suitable for application as a thermal barrier coating material and it may possess good thermal stress-induced cracking resistance. | Zifan Zhao Huimin Xiang Fu-Zhi Dai Zhijian Peng Yanchun Zhou | 2019 | Journal of Materials Science & Technology2019，35，11： | 25 |
| 3 | (La0.2Ce0.2Nd0.2Sm0.2Eu0.2)PO4: A high-entropy rare-earth phosphate monazite ceramic with low thermal conductivity and good compatibility with Al2O3显示文摘Low thermal conductivity, matched thermal expansion coefficient and good compatibility are general requirements for the environmental/thermal barrier coatings(EBCs/TBCs) and interphases for Al2O3 f/Al2O3 composites. In this work, a novel high-entropy(HE) rare-earth phosphate monazite ceramic (La0.2Ce0.2Nd0.2Sm0.2Eu0.2)PO4 is designed and successfully synthesized. This new type of HE rare-earth phosphate monazite exhibits good chemical compatibility with Al2O3, without reaction with Al2O3 as high as 1600℃ in air. Moreover, the thermal expansion coefficient(TEC) of HE (La0.2Ce0.2Nd0.2Sm0.2Eu0.2)PO4(8.9 × 10^-6/℃ at 300–1000℃) is close to that of Al2O3. The thermal conductivity of HE (La0.2Ce0.2Nd0.2Sm0.2Eu0.2)PO4 at room temperature is as low as 2.08 W·m^-1·K^-1, which is about 42% lower than that of La PO4. Good chemical compatibility, close TEC to that of Al2O3, and low thermal conductivity indicate that HE (La0.2Ce0.2Nd0.2Sm0.2Eu0.2)PO4 is suitable as a candidate EBC/TBC material and an interphase for Al2O3 f/Al2O3 composites. | Zifan Zhao Heng Chen Huimin Xiang Fu-Zhi Dai Xiaohui Wang Zhijian Peng Yanchun Zhou | 2019 | Journal of Materials Science & Technology2019，35，12： | 15 |
| 4 | Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction显示文摘 | Mei Hua Jiang Bing Cai Ying Tuo Jiancheng Wang Zhi Jun Zang Xiang'an Tu Yong Gao Zhijian Su Weiqiang Li Guilan Li Min Zhang Jianwei Jiao Zi Wan Chunhua Deng Bruce T Lahn Andy Peng Xiang | 2014 | Cell Research2014，24，12： | 14 |
| 5 | High-entropy(Nd_(0.2)Sm_(0.2)Eu_(0.2)Y_(0.2)Yb_(0.2))_(4)Al_(2)O_(9) with good high temperature stability,low thermal conductivity,and anisotropic thermal expansivity显示文摘The critical requirements for the environmental barrier coating(EBC)materials of silicon-based ceramic matrix composites(CMCs)include good tolerance to harsh environments,thermal expansion matches with the interlayer mullite,good high-temperature phase stability,and low thermal conductivity.Cuspidine-structured rare-earth aluminates RE_(4)Al_(2)O_(9) have been considered as candidates of EBCs for their superior mechanical and thermal properties,but the phase transition at high temperatures is a notable drawback of these materials.To suppress the phase transition and improve the phase stability,a novel cuspidine-structured rare-earth aluminate solid solution(Nd_(0.2)Sm_(0.2)Eu_(0.2)Y_(0.2)Yb_(0.2))_(4)Al_(2)O_(9) was designed and successfully synthesized inspired by entropy stabilization effect of high-entropy ceramics(HECs).The as-synthesized HE(Nd_(0.2)Sm_(0.2)Eu_(0.2)Y_(0.2)Yb_(0.2))_(4)Al_(2)O_(9) exhibits a close thermal expansion coefficient(6.96×10^(-6) K^(-1) at 300-1473 K)to that of mullite,good phase stability from 300 to 1473 K,and low thermal conductivity(1.50 W·m^(-1)·K^(-1) at room temperature).In addition,strong anisotropic thermal expansion has been observed compared to Y_(4)Al_(2)O_(9) and Yb_(4)Al_(2)O_(9).The mechanism for low thermal conductivity is attributed to the lattice distortion and mass difference of the constituent atoms,and the anisotropic thermal expansion is due to the anisotropic chemical bonding enhanced by the large size rare-earth cations. | Zifan ZHAO Huimin XIANG Heng CHEN Fu-Zhi DAI Xiaohui WANG Zhijian PENG Yanchun ZHOU | 2020 | Journal of Advanced Ceramics2020，9，5： | 12 |
| 6 | (TiZrHf)P2O7: An equimolar multicomponent or high entropy ceramic with good thermal stability and low thermal conductivity显示文摘Zr P2O7 is a promising material for high temperature insulating applications. However, decomposition above 1400℃ is the bottleneck that limiting its application at high temperatures. To improve the thermal stability, a novel multicomponent equimolar solid solution(Ti Zr Hf)P2O7 was designed and successfully synthesized in this work inspired by high-entropy ceramic(HEC) concept. The as-synthesized(Ti Zr Hf)P2O7 exhibits good thermal stability, which is not decomposed after heating at 1550℃ for 3 h. It also shows lower thermal conductivity(0.78 W m^-1 K^-1) compared to the constituting metal pyrophosphates Ti P2O7, Zr P2O7 and Hf P2O7. The combination of high thermal stability and low thermal conductivity renders(Ti Zr Hf)P2O7 promising for high temperature thermal insulating applications. | Zifan Zhao Huimin Xiang Fu-Zhi Dai Zhijian Peng Yanchun Zhou | 2019 | Journal of Materials Science & Technology2019，35，10： | 12 |
| 7 | High-entropy(Y0.2Nd0.2Sm0.2Eu0.2Er0.2)AlO3:A promising thermal/environmental barrier material for oxide/oxide composites显示文摘Yttrium aluminum perovskite(YAl O3)is a promising candidate material for environmental barrier coatings(EBCs)to protect Al2 O3 f/Al2 O3 ceramic matrix composites(CMCs)from the corrosion of high-temperature water vapor in combustion environments.Nevertheless,the relatively high thermal conductivity is a notable drawback of YAl O3 for environmental barrier coating application.Herein,in order to make REAl O3 more thermal insulating,a novel high-entropy rare-earth aluminate ceramic(Y0.2Nd0.2Sm0.2Eu0.2Er0.2)AlO3 was designed and synthesized.The as-prepared(Y0.2Nd0.2Sm0.2Eu0.2Er0.2)AlO3 ceramic possesses close thermal expansion coefficient(9.02×10-6/oC measured from room temperature to 1200℃)to that of Al2 O3.The thermal conductivity of(Y0.2Nd0.2Sm0.2Eu0.2Er0.2)AlO3 at room temperature is 4.1 W·m-1K-1,which is almost one third of the value of YAl O3.Furthermore,to effectively prevent the penetration of water vapor from possible pores/cracks of coating layer,which are often observed in T/EBCs,a tri-layer EBC system REAl O3/RE3 Al5 O12/(Al2 O3 f/Al2 O3 CMCs)is designed.Close thermal expansion coefficient to Al2 O3 and low thermal conductivity of(Y0.2Nd0.2Sm0.2Eu0.2Er0.2)AlO3,as well as the formation of dense garnet layer at(Y0.2Nd0.2Sm0.2Eu0.2Er0.2)AlO3/Al2 O3 interface,indicate that this new type of high-entropy ceramic is suitable as a candidate environmental barrier coating material for Al2 O3 f/Al2 O3 CMCs. | Zifan Zhao Heng Chen Huimin Xiang Fu-Zhi Dai Xiaohui Wang Wei Xu Kuang Sun Zhijian Peng Yanchun Zhou | 2020 | Journal of Materials Science & Technology2020，47，12： | 9 |
| 8 | Nine-month angiographic and two-year clinical follow-up of polymer-free sirolimus-eluting stent versus durable-polymer sirolimus-eluting stent for coronary artery disease: the Nano randomized trial显示文摘 | Zhang Yaojun Chen Fang Takashi Muramatsu Xu Bo Li Zhanquan Ge Junbo He Qing Yang Zhijian Li Shumei Wang Lefeng Wang Haichang He Ben Li Kang Qi Guoxian Li Tianchang Zeng Hesong Peng Jianjun Jiang Tieming Zeng Qiutang Zhu Jianhua Fu Guosheng Christos V. Bourantas Patrick W. Serruys Huo Yong | 2014 | Chinese Medical Journal2014，，11： | 8 |
| 9 | Progress on rare-earth doped ZnO-based varistor materials显示文摘Rare-earth(RE)doping can greatly enhance the voltage gradient of ZnO-based varistors,and their nonlinear coefficient,leakage current,energy absorption capability,through-current capability and residual voltage can also be improved to certain extent.In this review,the progress on RE-doped ZnO-based varistor materials in recent years was summarized.The mechanism of RE doping on the electrical performance of ZnO varistors was analyzed.The issues in exploring new ZnO-based varistor materials by RE doping were indicated,and the development trends in this area were proposed. | Feng JIANG Zhijian PENG Yanxu ZANG Xiuli FU | 2013 | Journal of Advanced Ceramics2013，2，3： | 6 |
| 10 | Enhancing Differential Evolution with Commensal Learning and Uniform Local Search显示文摘Differential evolution(DE) is a popular and powerful evolutionary algorithm for global optimization problems. However, the combination of mutation strategies and parameter settings of DE is problem dependent and choosing the suitable one is a challenge work and timeconsuming. In addition, the deficiency in local exploitation also has a significant influence on the performance of DE.In order to solve these problems, a DE variant with Commensal learning and uniform local search(CUDE) has been proposed in this paper. In CUDE, commensal learning is proposed to adaptively select optimal mutation strategy and parameter setting simultaneously under the same criteria. Moreover, uniform local search enhances exploitation ability. Comprehensive experiment results on all the CEC2013 test suite and comparison with the state-of-the-art DE variants indicate that the CUDE is very competitive. | PENG Hu WU Zhijian DENG Changshou | 2017 | Chinese Journal of Electronics2017，26，4： | 5 |
| 11 | Why can soil maintain its endless eco-cycle? The relationship between the mechanical properties and ecological attributes of soil显示文摘Dear Editors,Why can soil maintain its endless eco-cycle to sustain the growth of plants?This mystery of nature can be resolved by revealing the relationship between the mechanical properties and ecological attributes of soil.Traditionally,soil science[1-3]is divided into two main categories:pedology and edaphology.In addition,soil mechanics addresses soil from the perspective of mechanics and engineering[4,5].However,no inherent | ZhiJian Yi ChaoHua Zhao JianYi Gu QingGuo Yang Ya Li Kai Peng | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，10： | 4 |
| 12 | Applications of polymer single nanochannels in biosensors显示文摘There are many elaborate masterpieces exist in natural world. Learning from nature, people developed serial intelligent biomimetic devices. Biomimetic smart nanochannels received widespread attention for mimicking biological processes in bodies. Excellent stability, tailorable surface characteristics and nano-size effects rend polymer single nanochannel an ideal candidate for constructing sensitive and reproducible biosensors. Nanochannels are responsive for special analytes while appropriate recognition elements are modified in channels wall. In this review, we summarized recent works in contructing biosensors that are using polymer single nanochannels for detecting various analytes. | HOU GuangLei PENG ZhiJian TIAN Ye ZHANG HuaCheng JIANG Lei | 2013 | Chinese Science Bulletin2013，58，13： | 4 |
| 13 | DCZ0801,a novel compound,induces cell apoptosis and cell cycle arrest via MAPK pathway in multiple myeloma显示文摘Multiple myeloma(MM)is a refractory malignant hematological malignancy,and many therapeutic strategies have been developed to cure patients with MM.DCZ0801 is a compound that consists of oxophenamide and pterostilbene.The role of these compounds in hematological cancers such as MM has yet to be studied.In this study,we explored the potential mechanism of DCZ0801 action,its anti-tumor activity both in vitro and in vivo on MM.This study was carried out via cell cycle proliferation assay,apoptotic analysis,western blot analysis,and examination of xenotransplantation model of tumors.The in vitro studies revealed that DCZ0801 could inhibit cell proliferation and induce apoptosis by regulating both caspase-dependent and mitogen-activated protein kinase signaling pathways,inducing S-phase arrest of the cell cycle related to downregulation of CDK2,cyclin-A2,and CDC25A protein expression.The in vivo studies showed that DCZ0801 could significantly reduce the size of the tumors in nude mice.Our results demonstrated that DCZ0801 may emerge as the new therapeutic option for the patient with MM. | Ting Zhang Bo Li Qilin Feng Zhijian Xu Cheng Huang Huiqun Wu Zhangbo Chen Liangning Hu Lu Gao Peng Liu Guang Yang Hui Zhang Kang Lu Tingye Li Yi Tao Xiaosong Wu Jumei Shi Weiliang Zhu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，5： | 3 |
| 14 | Volumetric modulation arc radiotherapy with flattening filter-free beams compared with conventional beams for nasopharyngeal carcinoma:a feasibility study显示文摘There is increasing interest in the clinical use of flattening filter-free(FFF) beams.In this study,we aimed to investigate the dosimetric characteristics of volumetric modulated arc radiotherapy(VMAT) with FFF beams for nasopharyngeal carcinoma(NPC).Ten NPC patients were randomly selected to undergo a RapidArc plan with either FFF beams(RA-FFF) or conventional beams(RA-C).The doses to the planning target volumes(PTVs),organs at risk(OARs),and normal tissues were compared.The technical delivery parameters for RapidArc plans were also assessed to compare the characteristics of FFF and conventional beams.Both techniques delivered adequate doses to PTVs.For PTVs,RA-C delivered lower maximum and mean doses and improved conformity and homogeneity compared with RA-FFF.Both techniques provided similar maximum doses to the optic nerves and lenses.For the brain stem,spinal cord,larynx,parotid glands,oral cavity,and skin,RA-FFF showed significant dose increases compared to RA-C.The dose to normal tissue was lower in RA-FFF.The monitor units(MUs) were(536 ± 46) MU for RA-FFF and(501± 25) MU for RA-C.The treatment duration did not significantly differbetween plans.Although both treatment plans could meet clinical needs,RA-C is dosimetrically superior to RA-FFF for NPC radiotherapy. | Mingzan Zhuang Tuodan Zhang Zhijian Chen Zhixiong Lin Derui Li Xun Peng Qingchun Qiu Renhua Wu | 2013 | Chinese Journal of Cancer2013，32，7： | 3 |
| 15 | Effective passivation of black phosphorus transistor against ambient degradation by an ultra-thin tin oxide film显示文摘Recently, two-dimensional (2D) layered semiconducting materials have been considered as promising channel materials to construct aggressively-scaled transistors owing to their excellent electrostatics and remained high carrier mobility even at atomic thickness (1,2)Among all of the emerging 2D semiconductors. | Dianzhong Wu Zhijian Peng Chuanhong Jin Zhiyong Zhang | 2019 | Science Bulletin2019，64，9： | 2 |
| 16 | Porous SiC Prepared Using Fine α-Al2O3 and SiC Powders as Sintering Additives显示文摘A reaction bonding technique and a method of layer coating were developed to fabricate porous SiC.The green body was prepared using 250.0μm SiC particles as the raw material,fineα-Al2O3 and SiC powders with mass ratio of 2.5:1as sintering additives,65.2μm graphite as the pore-forming agent and polyvinyl alcohol(PVA)as the binder.The micro powders were coated on the surface of coarse SiC particles.After sintering,fine SiC particles were oxidized to silica(SiO2)then transforming into cristobalite,which finally reacted withα-Al2O3 to produce mullite(3Al2O3·2SiO2).The results show that SiC particles are bonded by the mullite and oxidation-derived SiO2.The apparent porosity of the specimens decreases from 31.3%to 20.5%with the amount of micro powders increasing from 5 mass%to 20 mass%.The bending strength increases at the first stage and then decreases with the increase of fine powders,and the specimen with 10 mass%of fine powders shows relatively high bending strength of 23.5 MPa. | LIU Jiadong PENG Zhijian LIU Qingzhu SUN Guangchao LIU Kaiqi | 2019 | China's Refractories2019，28，2： | 2 |
| 17 | Enhancing Firefly Algorithm with Best Neighbor Guided Search Strategy显示文摘Firefly algorithm(FA)is a recently-proposed swarm intelligence technique.It has shown good performance in solving various optimization problems.According to the standard firefly algorithm and most of its variants,a firefly migrates to every other brighter firefly in each iteration.However,this method leads to defects of oscillations of positions,which hampers the convergence to the optimum.To address these problems and enhance the performance of FA,we propose a new firefly algorithm,which is called the Best Neighbor Firefly Algorithm(BNFA).It employs the best neighbor guided strategy,where each firefly is attracted to the best firefly among some randomly chosen neighbors,thus reducing the firefly oscillations in every attraction-induced migration stage,while increasing the probability of the guidance a new better direction.Moreover,it selects neighbors randomly to prevent the firefly form being trapped into a local optimum.Extensive experiments are conducted to find out the optimal parameter settings.To verify the performance of BNFA,13 classical benchmark functions are tested.Results show that BNFA outperforms the standard FA and other recently proposed modified FAs. | WU Shuangke WU Zhijian PENG Hu | 2019 | Wuhan University Journal of Natural Sciences2019，24，6： | 2 |
| 18 | Blue light-induced rare-earth free phosphors for the highly sensitive and selective imaging of latent fingerprints based on enhanced hydrophobic interaction显示文摘The demand for in-situ detection of latent fingerprints(LFPs)in ways of high sensitivity,high selectivity,high contrast,low cost and user-friendly is still urgent.To overcome this challenge,a moisture-stable,red-emitting fluoride phosphor K_(3)AlF_(6):Mn^(4+)(KAF:Mn^(4+))with an organic hydrophobic skin was prepared.The phosphor has a uniform and superfine morphology with excellent luminescence properties.More importantly,this non-ultraviolet(UV)or non-near infrared(NIR)induced phosphor was proved to be an ideal fluorescent label for LFP imaging,which is both friendly for touch DNA analysis and compatible to forensic light sources.The well-defined ridge details with little background interference on various surfaces were presented by the oleic acid(OA)modified KAF:Mn^(4+)(KAF:Mn^(4+)-OA)phosphor in few seconds using the powder dusting method.To confirm the high selectivity of KAF:Mn^(4+)-OA for LFP imaging,an efficient quantitative evaluation method is proposed with the aid of ImageJ&Origin software.Due to the superiority of the Mn^(4+)-doped fluoride for the rapid imaging of LFPs in terms of lowcost,high compatibility and good availability,it is expected to be a promising candidate for forensic science as well as fluorescence imaging in other fields instead of rare earth luminescent materials. | Di Peng Shengan He Yuyan Zhang Liqin Yao Wendong Nie Zhijian Liao Wenting Cai Xinyu Ye | 2022 | Journal of Materiomics2022，8，1： | 2 |
| 19 | A review of cemented carbides for rock drilling: An old but still tough challenge in geo-engineering显示文摘 | Xiaoyong Ren Hezhuo Miao Zhijian Peng | 2013 | International Journal of Refractory Metals and Hard Materials2013，，： | 1 |
| 20 | Effect of Pr3+ doping on magnetic and dielectric properties of Ni-Zn ferrites by 'one-step synthesis'显示文摘 | Peng Zhijian Fu Xiuli Ge Huilin | 2011 | J Magn Magn Mater2011，323，20： | 1 |
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