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| 1 | Anatomical and chemical characteristics associated with lodging resistance in wheat显示文摘Anatomical and chemical characteristics of stems affect lodging in wheat(Triticum aestivum L.) cultivars. Traits associated with lodging resistance, such as plant height, stem strength, culm wall thickness, pith diameter, and stem diameter, were extensively investigated in earlier studies. However, the solid stem trait was rarely considered. In this study, we measured a range of anatomical and chemical characteristics on solid and hollow stemmed wheat cultivars. Significant correlations were detected between resistance to lodging and several anatomical features, including width of mechanical tissue, weight of low internodes, and width of stem walls. Morphological features that gave the best indication of improved lodging resistance were increased stem width, width of mechanical tissue layer, and stem density. Multiple linear regression analysis showed that 99% of the variation in lodging resistance could be explained by the width of the mechanical tissue layer, suggesting that solid stemmed wheat has several anatomical features for increasing resistance to lodging. In addition, microsatellite markers GWM247 and GWM340 were linked to a single solid stem QTL on chromosome 3BL in a population derived from the cross Xinongshixin(solid stem)/Line 3159(hollow stem). These markers should be valuable in breeding wheat for solid stem. | Eryan Kong Dongcheng Liu Xiaoli Guo Wenlong Yang Jiazhu Sun Xin Li Kehui Zhan Dangqun Cui Jinxing Lin Aimin Zhang | 2013 | The Crop Journal2013，1，1： | 43 |
| 2 | Genomic Distribution of Quantitative Trait Loci for Yield and Yield-related Traits in Common Wheat显示文摘A major objective of quantitative trait locus (QTL) studies is to find genes/markers that can be used in breeding programs via marker assisted selection (MAS).We surveyed the QTLs for yield and yieldrelated traits and their genomic distributions in common wheat (Triticum aestivum L.) in the available published reports.We then carried out a meta-QTL (MQTL) analysis to identify the major and consistent QTLs for these traits.In total,55 MQTLs were identified,of which 12 significant MQTLs were located on wheat chromosomes 1A,1B,2A,2D,3B,4A,4B,4D and 5A.Our study showed that the genetic control of yield and its components in common wheat involved the important genes such as Rht and Vrn.Furthermore,several significant MQTLs were found in the chromosomal regions corresponding to several rice genomic locations containing important QTLs for yield related traits.Our results demonstrate that meta-QTL analysis is a powerful tool for confirming the major and stable QTLs and refining their chromosomal positions in common wheat,which may be useful for improving the MAS efficiency of yield related traits. | Li-Yi Zhang Dong-Cheng Liu Xiao-Li Guo Wen-Long Yang Jia-Zhu Sun Dao-Wen Wang Aimin Zhang | 2010 | Journal of Integrative Plant Biology2010，52，11： | 11 |
| 3 | Dissecting and Enhancing the Contributions of High-Molecular-Weight Glutenin Subunits to Dough Functionality and Bread Quality显示文摘Dear Editor, Seed storage proteins (SSPs) are frequently important determinants of crop quality traits (Shewry and Casey,1999).Dissecting and enhancing the genetic contributions of individual SSPs to their target traits are essential for effectively improving crop quality attributes.However,such a task is often difficult to accomplish,because SSPs are frequently expressed from multigene families and exhibit strong allelic variation.Consequently,detailed knowledge of the function of individual SSPs in crop quality trait is still limited.This scenario is well illustrated by high-molecular-weight glutenin subunits (HMWGSs),a complex family of SSPs that are involved in wheat enduse quality through affecting dough functionality (Békés,2012;Rasheed et al.,2014). | Yiwen Li Xuefi An Ran Yang Xiaomin Guo Guidong Yue Renchun Fan Bin Li Zhensheng Li Kunpu Zhang Zhenying Dong Luyan Zhang Jiankang Wang Xu Jia Hong-Qing Ling Aimin Zhang Xiangqi Zhang Daowen Wang | 2015 | Molecular Plant2015，8，2： | 9 |
| 4 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 5 | Effect of tempering temperature on the mechanical properties and microstructure of an copper-bearing low carbon bainitic steel显示文摘The effect of tempering temperature on the microstructure and mechanical properties of ultra-high strength,copper- bearing,low-carbon bainitic steel has been investigated in the experiment.The results showed that the microstructure was mainly the laths of bainite in the as-quenched steel.The bainitic laths were restored and combined after the steel tempered at various tempera- tures.There were martensite/austenite(M/A)islands and numerous dislocations within and between the bainitic laths,while very fine precipitates ofε-Cu were also observed within the laths.With increasing the tempered temperature from 400 to 600℃,the yield strength(YS)increased from 877 to 957 MPa,whereas the ultimate tensile strength(UTS)decreased from 1020 to 985 MPa.The Charpy V-notch(CVN)varied from 68.5 to 42 J,and the value was minimal for the steel tempered at 500℃. | Aimin Guo Xinli Song Jinquan Tang Zexi Yuan | 2008 | Journal of University of Science and Technology Beijing2008，15，1： | 6 |
| 6 | Effect of zirconium addition on the austenite grain coarsening behavior and mechanical properties of 900 MPa low carbon bainite steel显示文摘The ultra-fine bainitic microstructure of a 900 MPa low carbon bainitic Cu-Ni-Mo-B steel was obtained by a newly de-veloped relaxation precipitation control (RPC) phase transformation processing. In a pan-cake like prior-austenite grain, the micro-structure consisted of lath bainite, a little of abnormal granular bainite, and acicular ferrite. The effect of zirconium carbonitrides on the austenite grain coarsening behavior was studied by transmission electron microscopy (TEM). The results show that, the lath is narrower with increasing cooling rate. The ratio of all kinds of bainitic microstructure is proper with the intermediate cooling rate; and Zr-containing precipitates distribute uniformly, which restrains austenite grain growing in heat-affected welding zone. | Jia Guo Aimin Guo Hui Guo Ying Wang Jing Li Xinlai He | 2008 | Journal of University of Science and Technology Beijing2008，15，6： | 3 |
| 7 | Latest Development and Application of High Strength and Heavy Gauge Pipeline Steel in China显示文摘 | Zhang Yongqing Guo Aimin Shang Chengjia Liu Qingyou J. Malcolm Gray Frank Barbaro | 2016 | Journal of Mechanics Engineering and Automation2016，6，1： | 3 |
| 8 | Comparing the diurnal variations in the SuperMAG auroral electrojet indices SML and SMU显示文摘Diurnal variations of the SuperMAG auroral electrojet indices(SML and SMU)were examined for the period of 1980–2010,and the differences between SML and SMU were especially analyzed.The diurnal variation of SML with a maximum at around 1100 UT has a prenoonpostnoon asymmetry.At solstices,the diurnal variation of SML is much stronger than that at equinoxes.For the SMU,two maxima are recorded in the diurnal variation with the bigger one at 1700 UT and the smaller one at 0400 UT.The seasonal variations are not obvious in the UT variation characteristics of SMU although the intensity of SMU is changed remarkably season by season.For both SML and SMU,the contributing stations are located at higher geomagnetic latitude around 1600 UT and at lower geomagnetic latitude around 0400 UT.These results indicate that:(1)the SML is mostly controlled by the convection electric field.Its diurnal variation is mainly correlated with the equinoctial and R-M hypothesis;(2)the SMU is largely controlled by the ionospheric conductance.Its diurnal variation is tightly correlated with the solar radiation. | Yuan Wang Aimin Du Gengxiong Chen Xin Cao Ying Zhang Min Li Xiaocan Liu Jianpeng Guo | 2014 | Chinese Science Bulletin2014，59，29： | 2 |
| 9 | Microstructure and properties of glycerol plasticized soy protein plastics containing castor oil显示文摘 | Huafeng Tian Wenqian Wu Gaiping Guo Bagen Gaolun Qingqing Jia Aimin Xiang | 2011 | Journal of Food Engineering2011，，3： | 2 |
| 10 | PCR-based isolation and identification of full-length low-molecular-weight glutenin subunit genes in bread wheat (Triticum aestivum L.)显示文摘 | Xiaofei Zhang Dongcheng Liu Wei Jiang Xiaoli Guo Wenlong Yang Jiazhu Sun Hongqing Ling Aimin Zhang | 2011 | Theoretical and Applied Genetics2011，，8： | 1 |
| 11 | Treatment of distal tibial shaft fractures by three different surgical methods: a randomized, prospective study显示文摘 | Yongchuan Li Xi Jiang Qinghe Guo Lei Zhu Tianwen Ye Aimin Chen | 2014 | International Orthopaedics2014，，6： | 1 |
| 12 | Impact toughness of a gradient hardened layer of Cr5Mo1V steel treated by laser shock peening显示文摘Laser shock peening(LSP) is a widely used surface treatment technique that can effectively improve the fatigue life and impact toughness of metal parts.Cr5Mo1 V steel exhibits a gradient hardened layer after a LSP process.A new method is proposed to estimate the impact toughness that considers the changing mechanical properties in the gradient hardened layer.Assuming a linearly gradient distribution of impact toughness,the parameters controlling the impact toughness of the gradient hardened layer were given.The influence of laser power densities and the number of laser shots on the impact toughness were investigated.The impact toughness of the laser peened layer improves compared with an untreated specimen,and the impact toughness increases with the laser power densities and decreases with the number of laser shots.Through the fracture morphology analysis by a scanning electron microscope,we established that the Cr5Mo1 V steel was fractured by the cleavage fracture mechanism combined with a few dimples.The increase in the impact toughness of the material after LSP is observed because of the decreased dimension and increased fraction of the cleavage fracture in the gradient hardened layer. | Weiguang Xia Lei Li Yanpeng Wei Aimin Zhao Yacong Guo Chenguang Huang Hongxiang Yin Lingchen Zhang | 2016 | Acta Mechanica Sinica2016，32，2： | 1 |
| 13 | An analysis of the microstructure of the heat-affected zone of an ultra-low carbon and niobium-bearing acicular ferrite steel using EBSD and its relationship to mechanical properties显示文摘 | Aimin Guo R.D.K. Misra Jibin Liu Ling Chen Xinlai He S.J. Jansto | 2010 | Materials Science & Engineering A2010，，23： | 1 |
| 14 | Ultrahigh strengthand low yield ratio of niobuium-microalloyed 900 MPa pipelinesteel with nano/ultrafine bainitic lath显示文摘 | Guo Aimin Misra R D K Xu Jinqiao | 2010 | Materials Science andEngineering A2010，527，1617： | 1 |
| 15 | Grain refinement of supemlloy K3 and K4169 by the addition of refiners显示文摘 | Xiong Yuhua Yang Aimin Guo Yiping | 2001 | Science and Technology of Advanced Materials2001，2，： | 1 |
| 16 | Grain refinement of superalloy K3 and K4169 by the addition of refiners 显示文摘 | Xiong Yuhua Yang Aimin Guo Yiping | 2001 | Science and rechnology of Advanced Materials2001，，2： | 1 |
| 17 | Novel Natural Allelic Variations at the Rht-1 Loci in Wheat显示文摘Plant height is an important agronomic trait.Dramatic increase in wheat yield during the'green revolution'is mainly due to the widespread utilization of the Reduced height(Rht)-1 gene.We analyzed the natural allelic variations of three homoeologous loci Rht-A1,Rht-B1,and Rht-D1 in Chinese wheat(Triticum aestivum L.)micro-core collections and the Rht-B1/D1 genotypes in over 1,500 bred cultivars and germplasms using a modifed EcoTILLING.We identifed six new Rht-A1 allelic variations(Rht-A1b–g),eight new Rht-B1 allelic variations(Rht-B1h–o),and six new Rht-D1 allelic variations(Rht-D1e–j).These allelic variations contain single nucleotide polymorphisms(SNPs)or small insertions and deletions in the coding or uncoding regions,involving two frame-shift mutations and 15 missenses.Of which,Rht-D1e and Rht-D1h resulted in the loss of interactions of GID1-DELLA-GID2,Rht-B1i could increase plant height.We found that the Rht-B1h contains the same SNPs and 197 bp fragment insertion as reported in Rht-B1c.Further detection of Rht-B1h in Tibet wheat germplasms and wheat relatives indicated that Rht-B1c may originate from Rht-B1h.These results suggest rich genetic diversity at the Rht-1 loci and provide new resources for wheat breeding. | Aixia Li Wenlong Yang Xueyuan Lou Dongcheng Liu Jiazhu Sun Xiaoli Guo Jing Wang Yiwen Li Kehui Zhan Hong-Qing Ling Aimin Zhang | 2013 | Journal of Integrative Plant Biology2013，55，11： | 1 |
| 18 | Paclitaxel liposome for injection (Lipusu) plus cisplatin versus gemcitabine plus cisplatin in the first-line treatment of locally advanced or metastatic lung squamous cell carcinoma: A multicenter, randomized, open-label, parallel controlled clinical study显示文摘Background:Lipusu is the first commercialized liposomal formulation of pacli-taxel and has demonstrated promising efficacy against locally advanced lung squamous cell carcinoma(LSCC)in a small-scale study.Here,we conducted a multicenter,randomized,phase 3 study to compare the efficacy and safety of cis-platin plus Lipusu(LP)versus cisplatin plus gemcitabine(GP)as first-line treat-ment in locally advanced or metastatic LSCC.Methods:Patients enrolled were aged between 18 to 75 years,had locally advanced(clinical stage IIIB,ineligible for concurrent chemoradiation or surgery)or metastatic(Stage IV)LSCC,had no previous systemic chemother-apy and at least one measurable lesion as per the Response Evaluation Criteria in Solid Tumors(version 1.1)before administration of the trial drug.The primary endpoint was progression-free survival(PFS).The secondary endpoints included objective response rate(ORR),disease control rate(DCR),overall survival(OS),and safety profiles.To explore the possible predictive value of plasma cytokines for LP treatment,plasma samples were collected from the LP group at baseline and first efficacy evaluation time and were then subjected to analysis by 45-Plex ProcartaPlex Panel 1 to detect the presence of 45 cytokines using the Luminex xMAP technology.The correlation between treatment outcomes and dynamic changes in the levels of cytokines were evaluated in preliminary analyses.Results:The median duration of follow-up was 15.4 months.237 patients in the LP group and 253 patients in the GP group were included in the per protocol set(PPS).In the PPS,the median PFS was 5.2 months versus 5.5 months in the LP and GP group(hazard rtio[HR]:1.03,P=0.742)respectively.The median OS was 14.6 months versus 12.5 months in the LP and GP group(HR:0.83,P=0.215).The ORR(41.8%versus 45.9%,P=0.412)and DCR(90.3%versus 88.1%,P=0.443)were also similar between the LP and GP group.A significantly lower proportion of patients in the LP group experienced adverse events(AEs)leading to treatment interruptions(10.9%versus 26.4%,P<0.001)or treatment termination(14.3%versus 23.1%,P=0.011).The analysis of cytokine levels in the LP group showed that low baseline levels of 27 cytokines were associated with an increased ORR,and 15 cytokines were associated with improved PFS,with 14 cytokines,including TNF-a,IFN-y,IL-6,and IL-8,demonstrating an overlapping trend.Conclusion:The LP regimen demonstrated similar PFS,OS,ORR and DCR as the GP regimen for patients with locally advanced or metastatic LSCC but had more favorable toxicity profiles.The study also identified a spectrum of different cytokines that could be potentially associated with the clinical benefit in patients who received the LP regimen. | Jie Zhang Yueyin Pan Qin Shi Guojun Zhang Liyan Jiang Xiaorong Dong Kangsheng Gu Huijuan Wang Xiaochun Zhang Nong Yang Yuping Li Jianping Xiong Tienan Yi Min Peng Yong Song Yun Fan Jiuwei Cui Gongyan Chen Wei Tan Aimin Zang Qisen Guo Guangqiang Zhao Ziping Wang Jianxing He Wenxiu Yao Xiaohong Wu Kai Chen Xiaohua Hu Chunhong Hu Lu Yue Da Jiang Guangfa Wang Junfeng Liu Guohua Yu Junling Li Jianling Bai Wenmin Xie Weihong Zhao Lihong Wu Caicun Zhou | 2022 | Cancer Communications2022，42，1： | 1 |
| 19 | Quantitative mRNA expression analysis of selected genes in patientswith early-stage hypothyroidism induced by treatment with iodine-131显示文摘 | Kun Guo Rui Gao Yan Yu Weixiao Zhang Yuxuan Yang Aimin Yang | 2015 | Molecular Medicine Reports2015，，： | 1 |
| 20 | Effect of fine - grained structure on the mechanical properties of superalloys K3 and K4169显示文摘 | Xiong Yuhua Yang Aimin Guo Yiping | 2001 | Science and Technology of Advanced Materials2001，2，1： | 1 |
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