|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation:Effects on virus replication and recurrent hepatitis显示文摘瞄准:决定 calcineurin 禁止者, cyclosporine 和 tacrolimus 的效果,在丙肝上,在病人的周期性的丙肝的病毒(HCV ) 复制和活动张贴肝移植。方法:在我们的中心为在 1999 和 2003 之间的联系 HCV 的肝肝硬化收到了肝移植的 107 个病人的一个队的数据回顾地被分析。浆液 HCV-RNA 的水平和周期性的肝炎的活动在作为主要抑制免疫力的代理人和没在移植以后在开始的 12 瞬间以内导致胆汁的复杂并发症的不那样类似的抑制免疫力的政体收到了 cyclosporine 或 tacrolimus 的 47 个病人之间被比较。结果:HCV-RNA 在移植以后在 3 瞬间以内增加了,但是 cyclosporine 组和 tacrolimus 组之间的差别是不足道的(在 12 瞬间的 P=0.49 ) 。另外,由浆液 transaminases 决定了的周期性的肝炎并且门发炎和纤维变性的组织学的分级没在 12 瞬间(P=0.34 ) 以后显示出有效差量。结论:一个主要抑制免疫力的代理人不在肝移植以后在感染 HCV 的病人影响周期性的肝炎的正式就职或严厉的 Cyclosporine 或 tacrolimus。 | Philip Hilgard Alisan Kahraman Nils Lehmann Cornelia Seltmann Susanne Beckebaum R Stefan Ross Hideo A Baba Massimo Malago Christoph E Broelsch Guido Gerken | 2006 | World Journal of Gastroenterology2006,12,5: | 235 |
| 2 | Endoscopic ultrasound guided radiofrequency ablation,for pancreatic cystic neoplasms and neuroendocrine tumors显示文摘AIM: To outline the feasibility, safety, adverse events and early results of endoscopic ultrasound(EUS)-radiofrequency ablation(RFA) in pancreatic neoplasms using a novel probe. METHODS: This is a multi-center, pilot safety feasibility study. The intervention described was radiofrequency ablation(RF) which was applied with an innovative monopolar RF probe(1.2 mm Habib EUS-RFA catheter) placed through a 19 or 22 gauge fine needle aspiration(FNA) needle once FNA was performed in patients with a tumor in the head of the pancreas. The HabibTM EUSRFA is a 1 Fr wire(0.33 mm, 0.013') with a working length of 190 cm, which can be inserted through the biopsy channel of an echoendoscope. RF power is applied to the electrode at the end of the wire to coagulate tissue in the liver and pancreas.RESULTS: Eight patients [median age of 65(range 27-82) years; 7 female and 1 male] were recruited in a prospective multicenter trial. Six had a pancreatic cysticneoplasm(four a mucinous cyst, one had intraductal papillary mucinous neoplasm and one a microcystic adenoma) and two had a neuroendocrine tumors(NET) in the head of pancreas. The mean size of the cystic neoplasm and NET were 36.5 mm(SD ± 17.9 mm) and 27.5 mm(SD ± 17.7 mm) respectively. The EUSRFA was successfully completed in all cases. Among the 6 patients with a cystic neoplasm, post procedure imaging in 3-6 mo showed complete resolution of the cysts in 2 cases, whilst in three more there was a 48.4% reduction [mean pre RF 38.8 mm(SD ± 21.7 mm) vs mean post RF 20 mm(SD ± 17.1 mm)] in size. In regards to the NET patients, there was a change in vascularity and central necrosis after EUS-RFA. No major complications were observed within 48 h of the procedure. Two patients had mild abdominal pain that resolved within 3 d. CONCLUSION: EUS-RFA of pancreatic neoplasms with a novel monopolar RF probe was well tolerated in all cases. Our preliminary data suggest that the procedure is straightforward and safe. The response ranged from complete resolution to a 50% reduction in size. | Madhava Pai Nagy Habib Hakan Senturk Sundeep Lakhtakia Nageshwar Reddy Vito R Cicinnati Iyad Kaba Susanne Beckebaum Panagiotis Drymousis Michel Kahaleh William Brugge | 2015 | World Journal of Gastrointestinal Surgery2015,7,4: | 23 |
| 3 | Paclitaxel-eluting balloon dilation of biliary anastomotic stricture after liver transplantation显示文摘AIM:To investigate the safety and effectiveness of endoscopic therapy with a paclitaxel-eluting balloon(PEB) for biliary anastomotic stricture(AS) after liver transplantation(LT).METHODS:This prospective pilot study enrolled 13 consecutive eligible patients treated for symptomatic AS after LT at the University Hospital of Münster between January 2011 and March 2014.The patients were treated by endoscopic therapy with a PEB and followed up every 8 wk by endoscopic retrograde cholangiopancreatography(ERCP).In cases of re-stenosis,further balloon dilation with a PEB was performed.Follow-up was continued until 24 mo after the last intervention.RESULTS:Initial technical feasibility,defined as successful balloon dilation with a PEB during the initial ERCP procedure,was achieved in 100% of cases.Long-term clinical success(LTCS),defined as no need for further endoscopic intervention for at least 24 mo,was achieved in 12 of the 13 patients(92.3%).The mean number of endoscopic interventions required to achieve LTCS was only 1.7 ± 1.1.Treatment failure,defined as the need for definitive alternative treatment,occurred in only one patient,who developed recurrent stenosis with increasing bile duct dilatation that required stent placement.CONCLUSION:Endoscopic therapy with a PEB is very effective for the treatment of AS after LT,and seems to significantly shorten the overall duration of endoscopic treatment by reducing the number of interventions needed to achieve LTCS. | Anna Hüsing Holger Reinecke Vito R Cicinnati Susanne Beckebaum Christian Wilms Hartmut H Schmidt Iyad Kabar | 2015 | World Journal of Gastroenterology2015,21,3: | 4 |
| 4 | Use of paclitaxel-eluting balloons for endotherapy of anastomotic strictures following liver transplantation显示文摘 | I. Kabar V. Cicinnati S. Beckebaum S. Cordesmeyer Y. Avsar H. Reinecke H. Schmidt | 2012 | Endoscopy2012,,12: | 2 |
| 5 | DNA-based immunotherapy: potential for treatment of chronic viral hepatitis显示文摘 | Beckebaum S Cicinnati VR Gerken G | 2002 | Rev Med Virol2002,12,5: | 2 |
| 6 | Orthotopic Liver Transplantation in Human-Immunodeficiency-Virus-Positive Patients in Germany显示文摘 | E. Anadol S. Beckebaum K. Radecke A. Paul A. Zoufaly M. Bickel F. Hitzenbichler T. Ganten J. Kittner M. Stoll C. Berg S. Manekeller J. C. Kalff T. Sauerbruch J. K. Rockstroh U. Spengler Raffaele Bruno | 2012 | AIDS Research and Treatment2012,,: | 2 |
| 7 | Optimized endoscopic treatment of ischemic-type biliary lesions after liver transplantation显示文摘 | Thomas Zoepf Evelyn J. Maldonado de Dechêne Alexander Dechêne Massimo Malágo Susanne Beckebaum Andreas Paul Guido Gerken Philip Hilgard | 2012 | Gastrointestinal Endoscopy2012,,3: | 2 |
| 8 | MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2 downregulation and increased cytostatic drug sensitivity显示文摘 | Leibo Xu Susanne Beckebaum Speranta Iacob Gang Wu Gernot M. Kaiser Arnold Radtke Chao Liu Iyad Kabar Hartmut H. Schmidt Xiaoyong Zhang Mengji Lu Vito R. Cicinnati | 2013 | Journal of Hepatology2013,,: | 2 |
| 9 | Hepatitis B virusinduced defect of monocyte - derived dendritic cells leads to impaired T helper type - 1 respons in vitro: mechanisms for viral immune escape显示文摘 | Beckebaum S Cicinnavi VR Zhang x | 2003 | Immunology2003,109,: | 1 |
| 10 | Effects of mycophenolate mofetil introduction in liver transplant patients: results from an observational, non‐interventional, multicenter study ( LOBSTER )显示文摘 | Hans J. Schlitt Sven Jonas Tom M. Ganten Gerrit Grannas Christian Moench Falk Rauchfuss Aiman Obed Giuseppe Tisone Antonio D. Pinna Giorgio E. Gerunda Susanne Beckebaum | 2013 | Clin Transplant2013,,3: | 1 |
| 11 | A randomized,controlled study to assess the conversion from ealcineurin-inhibitors to everolimus after liver transplantation-protect 显示文摘 | Fischer L Klempnauer J Beckebaum S | 2012 | Am J Trans- plant2012,12,7: | 1 |
| 12 | Reduction in the circulating pDC1/pDC2 ratio and impaired function of ex vivo-generated DC1 in chronic hepatitis B infection 显示文摘 | Beckebaum S Cicinnati VR Dworracki G | 2002 | Clin Immunol2002,104,2: | 1 |
| 13 | Major bile duct injuries after laparoscopic cholecystectomy: A tertiary center experience显示文摘 | Andrea Frilling M.D. Ph.D. Jun Li M.D. Frank Weber M.D. Nils Roman Frühauf M.D. Jennifer Engel Susanne Beckebaum M.D. Andreas Paul M.D. Thomas Z?pf M.D. Massimo Malago M.D. Ph.D. Christoph Erich Broelsch M.D. Ph.D | 2004 | Journal of Gastrointestinal Surgery2004,,6: | 1 |
| 14 | Hepatitis B virus induced defect of monocyte derived dendritic cells leads to impaired T helper type 1 response in vftro:mechanisms for viral immune escape 显示文摘 | Beckebaum S Cicinnati VR Zhang X | 2003 | Immunol2003,109,4: | 1 |
| 15 | Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro:mechanisms for viral immune escape显示文摘 | Beckebaum S Cicinnati VR Zhang X | 2003 | Immunology2003,109,4: | 1 |
| 16 | Increased levels of interleukin-lO in serum from patients with hepatocellular carcinoma correlate with profound numerical deficiencies and immature phenotype of circulating dendritic cell subsets显示文摘 | Beckebaum S Zhang X Chen X | 2004 | Clin Cancer Res2004,10,21: | 1 |
| 17 | Does long- term ventilation with PEEP > or = 10mbar influence graft-func- tion in patients following liver transplantation? 显示文摘 | Koeabayoglu P Treckmann JW Beckebaum S | 2010 | Hepato- gastroenterology2010,57,: | 1 |
| 18 | Inerensed levels of intedeukin10 in serum from patients with hepatocellular carcinoma correlate with profound numerical deficiencies and immature phenotype of circulating dendritic cell subsets显示文摘 | Beckebaum S Zhang X Chen X | 2004 | Clin Cancer Res2004,10,21: | 1 |
| 19 | Hepatitis B vims-inducec defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro:mechanisms for viral immune escape显示文摘 | Cicinnati VR Zhang X | 2003 | Immunology2003,109,4: | 1 |
| 20 | Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro:mechanisms for viral immune escape显示文摘 | Cieinnati VR Zhang X | 2003 | Immunology2003,109,4: | 1 |