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| 1 | Groundwater Contamination with NO_3-N in a Wheat-Corn Cropping System in the North China Plain显示文摘The North China Plain,where summer corn(Zea mays L.)and winter wheat(Triticum aestivum L.)are the major crops grown,is a major agricultural area in China.Permeable soils make the region susceptible to groundwater pollution by NO_3-N,which is applied to fields in large amounts of more than 400 kg NO_3-N ha^(-1)as fertilizer.A field experiment was established in 2002 to examine the relationship among N fertilization rate,soil NO_3-N,and NO_3-N groundwater contamination.Two adjacent fields were fertilized with local farmers' N fertilization rate(LN)and double the normal application rate(HN),respectively,and managed under otherwise identical conditions.The fields were under a traditional summer corn/winter wheat rotation.Over a 22-month period,we monitored NO_3-N concentrations in both bulk soil and soil pore water in 20-40 cm increments up to 180 cm depth.We also monitored NO_3-N concentrations in groundwater and the depth of the groundwater table.No significant differences in soil NO_3-N were observed between the LN and HN treatment.We identified NO_3-N plumes moving downward through the soil profile.The HN treatment resulted in significantly higher groundwater NO_3-N,relative to the LN treatment,with groundwater NO_3-N consistently exceeding the maximum safe level of 10 mg L^(-1),but groundwater NO_3-N above the maximum safe level was also observed in the LN treatment after heavy rain.Heavy rain in June,July,and August 2003 caused increased NO_3-N leaching through the soil and elevated NO_3-N concentrations in the groundwater.Concurrent rise of the groundwater table into NO_3-N- rich soil layers also contributed to the increased NO_3-N concentrations in the groundwater.Our results indicate that under conditions of average rainfall,soil NO_3-N was accumulated in the soil profile.The subsequent significantly higher- than-average rainfalls continuously flushed the soil NO_3-N into deeper layers and raised the groundwater table,which caused continuous groundwater contamination with NO_3-N.The results suggest that under common farming practices in the North China Plain,groundwater contamination with NO_3-N was likely,especially during heavy rainfalls,and the degree of groundwater contamination appeared to be proportional to the N application rates.Decreasing fertilization rates, splitting fertilizer inputs,and optimizing irrigation scheduling had potential to reduce groundwater NO_3-N contamination. | ZHAO Bing-Zi ZHANG Jia-Bao M. FLURY ZHU An-Ning JIANG Qi-Ao BI Jin-Wei | 2007 | Pedosphere2007，17，6： | 20 |
| 2 | Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China:A multicenter retrospective study显示文摘Importance:The clinical characteristics of infectious mononucleosis(IM)in Chinese children have not been evaluated in multicenter studies,and the effectiveness of antiviral treatment are controversial.Objective:To investigate the clinical characteristics of Chinese children with IM and current status of antiviral therapy for affected patients.Methods:Hospitalized patients with IM were enrolled between 2018 and 2020 in five children’s hospitals in China.The clinical characteristics were compared among four age groups:<3 years,3-<6 years,6-<10 years,and≥10 years.The clinical characteristics of IM and effectiveness of antiviral therapy were compared among patients receiving acyclovir(ACV),ganciclovir(GCV),and no antiviral therapy(i.e.,non-antiviral group).Results:In total,499 patients were analyzed;most patients were 3-<6 years of age.The most common symptoms and signs included fever(100%),lymphadenopathy(98.6%),pharyngitis(86.4%),eyelid edema(76.8%),and snoring(72.9%).There were significant differences in rash,hepatomegaly,and liver dysfunction among the four age groups.Patients aged<3 years had a lower incidence of liver dysfunction and a higher incidence of rash.Among the 499 patients,50.1%were treated with GCV,26.3%were treated with ACV,and 23.6%received no antiviral therapy.Compared with the non-antiviral group,patients in the ACV and GCV groups had longer durations of fever(P<0.001).There were no significant differences in the incidences of complications among the three treatment groups.Interpretation:The incidence of IM in Chinese children peaked at 3-<6 years of age.Clinical features of IM varied according to age.Patients receiving antiviral therapy exhibited more serious clinical manifestations than did patients without antiviral therapy.The effectiveness of antiviral therapy for IM requires further analysis. | Huili Hu Huiling Deng Jing Bi Yi Xu Shuangjie Li Yue Xie Xinrong Sun Dongmeng Wang Xufang Li Wenxian Ouyang Bing Hu Yufeng Zhang He Tang Chunxiao Fang Hui Zhang Lingyun Guo Chen Wang Tianyi Wang Fengxia Yang Tao Jiang Zhengde Xie Gang Liu | 2021 | Pediatric Investigation2021，5，3： | 12 |
| 3 | Arbuscular mycorrhizal fungi ameliorate the chemical properties and enzyme activities of rhizosphere soil in reclaimed mining subsidence in northwestern China显示文摘In semi-arid region of northwestern China, underground mining subsidence often results in decreased vegetation coverage, impoverishment of soil fertility and water stress. In addition, the physical-chemical and biological properties of soil also change, resulting in more susceptible to degradation. In particular, subsidence causes disturbance of the symbioses of plant and microbe that can play a beneficial role in the establishment of vegetation communities in degraded ecosystems. The objective of this study was to evaluate the effects of revegetation with exotic arbuscular mycorrhizal fungi(AMF) inoculum on the chemical and biological properties of soil over time in mining subsidence areas. Soils were sampled at a depth up to 30 cm in the adjacent rhizosphere of Amorpha fruticose Linn. from five reclaimed vegetation communities in northwestern China. In August 2015, a field trial was set up with five historical revegetation experiments established in 2008(7-year), 2011(4-year), 2012(3-year), 2013(2-year) and 2014(1-year), respectively. Each reclamation experiment included two treatments, i.e., revegetation with exotic AMF inoculum(AMF) and non-AMF inoculum(the control). Root mycorrhizal colonization, glomalin-related soil protein(GRSP), soil organic carbon(SOC), soil nutrients, and enzyme activities were also assessed. The results showed that mycorrhizal colonization of inoculated plants increased by 33.3%–163.0% compared to that of non-inoculated plants(P<0.05). Revegetation with exotic AMF inoculum also significantly improved total GRSR(T-GRSP) and easily extracted GRSP(EE-GRSP) concentrations compared to control, besides the T-GRSP in 1-year experiment and the EE-GRSP in 2-year experiment. A significant increase in SOC content was only observed in 7-year AMF reclaimed soils compared to non-AMF reclaimed soils. Soil total N(TN), Olsen phosphorus(P) and available potassium(K) were significantly higher in inoculated soil after 1–7 years of reclamation(except for individual cases), and increased with reclamation time(besides soil Olsen P). The exotic AMF inoculum markedly increased the average soil invertase, catalase, urease and alkaline phosphatase by 23.8%, 21.3%, 18.8% and 8.6%, respectively(P<0.01), compared with the control. Root mycorrhizal colonization was positively correlated with soil parameters(SOC, TN and soil available K) and soil enzyme activities(soil invertase, catalase, urease and alkaline phosphatase) in both AMF and non-AMF reclaimed soils(P<0.05), excluding availableK in non-AMF reclaimed soils. T-GRSP(P<0.01) and EE-GRSP(P<0.05) were significantly correlated with the majority of edaphic factors, except for soil Olsen P. The positive correlation between root mycorrhizal colonization and available K was observed in AMF reclaimed soils, indicating that the AMF reclaimed soil with a high root mycorrhizal colonization could potentially accumulate available K in soils. Our findings concluded that revegetation with exotic AMF inoculum influenced soil nutrient availability and enzyme activities in the semi-arid ecosystem, suggesting that inoculating AMF can be an effective method to improve soil fertility and support restoration of vegetation communities under poor conditions like soil nutrient deficiency and drought. | QIU Lang BI Yinli JIANG Bin WANG Zhigang ZHANG Yanxu Yryszhan ZHAKYPBEK | 2019 | Journal of Arid Land2019，11，1： | 11 |
| 4 | Clinical Application of Loewenstein Occupational Therapy Cognitive Assessment Battery-Second Edition in Evaluating of Cognitive Function of Chinese Patients with Post-stroke Aphasia显示文摘Objective To investigate the clinical application value of Loewenstein Occupational Therapy Cognitive Assessment(LOTCA)battery in Chinese patients with post-stroke aphasia.Methods Cognitive functions of 59 Chinese patients with aphasia following a stroke were assessed with the Chinese version of the second edition of LOTCA battery and their linguistic functions were tested with the Western Aphasia Battery(WAB)Scale,respectively.The results of LOTCA were analyzed and compared across different groups,in the light of gender,age,educational background,the length of illness,and the degree of aphasia.Results Neither the score of subtests of the LOTCA nor the overall scores of LOTCA of aphasia patients with different gender and educational background differed(all P>0.05).In different age groups,apart from thinking operation(F=3.373,P=0.016),visuomotor organization(F=3.124,P=0.022),attention(F=3.729,P=0.009)and the total score(F=2.683,P=0.041),there was no difference in terms of the other subtest scores of LOTCA(all P>0.05).In the groups of different length of time with illness,apart from orientation(F=2.982,P=0.039)and attention(F=3.485,P=0.022),the score of other subtests and the total score of LOTCA were not different(all P>0.05).In the groups of different degree of aphasia,apart from attention(F=2.061,P=0.074),both the score of other subtests and the total score of LOTCA differed(all P<0.05).Conclusion LOTCA might be suitable to assessing the cognitive ability of post-stroke Chinese patients with aphasia. | Zeng-zhi Yu Shu-jun Jiang Jun Li Sheng Bi Fei Li Tao Xie Rui Wang Xiao-tan Zhang | 2013 | Chinese Medical Sciences Journal2013，28，3： | 9 |
| 5 | Rh-incompatible hemolytic disease of the newborn in Hefei显示文摘BACKGROUND Anti-D antibody is not the common cause of Rh-isoimmunization in Chinese neonatal jaundice.Recent change in national population policy has followed by an increase in Rh-isoimmunization related hemolytic disease of the newborn(HDN).Unfortunately,regional status of Rh-HDN is unavailable.We hypothesize that Rh-HDN in our region is most commonly due to anti-E antibody.AIM To investigate the prevalence of hemolytic disease of the newborn due to Rhisoimmunization in Hefei City.METHODS Retrospective review of data obtained from Children’s Hospital of Anhui and Hefei Blood Center between January 2017 and June 2019.Status of minor blood group antibody was studied in the corresponding mothers.RESULTS Totally 4138 newborns with HDN admitted during the study period and 116(2.8%)received blood exchange transfusion(BET).Eighteen newborns(0.43%)with proven Rh-incompatible HDN were identified.All were not the first-born baby.Thirteen mothers were RhD(+)(72%)and five were RhD(-).The distribution of Rh-related antibodies in mothers was ten anti-E(55%),five anti-D(27%),and for one anti-C,anti-c,and anti-E/c(6%)each.Thirteen(72.2%)were qualified for BET,relative risk for BET was 28.9 as compared to other types of HDN,but only 10 received due to parenteral refusal.All(100%)RhD related HDN received BET which is not significantly different from RhE related HDN(81.8%).CONCLUSION As expected,all Rh-incompatible HDN newborns were not the first-born.Contrary to the Caucasian population,anti-D induced HDN is not the most common etiology.In our region,anti-E(11/18,61%)is the most common cause of Rh-HDN. | Shao-Hua Bi Liang-Liang Jiang Li-Ying Dai Hong Zheng Jian Zhang Li-Li Wang Chao Wang Qiao Jiang Yu Liu Yong-Li Zhang Juan Wang Chao Zhu Guang-Hui Liu Ru-Jeng Teng | 2019 | World Journal of Clinical Cases2019，7，20： | 7 |
| 6 | ESR Dating of the Evolution of the Shuanghu Basin in the Northern Tibetan Plateau显示文摘The Shuanghu basin is a NE-trending rift basin bounded by NE-striking normal faults and NW-striking shear-extensional faults of the northern Tibetan Plateau. Four samples from calcite veins in marginal faults and one sample from mudstone (S-3) were collected for dating the evolution of the Shuanghu basin by using the ESR spectrograph of EXM-type. Ages were calculated according to the close-equilibrium model on the basis of the measured ESR signal spectra of samples, providing good chronological information. It is known from the ESR dating that the extensional faulting and rifting of the Shuanghu area began at 4.92 Ma B.P., followed by regional folding in 3.56-1.36 Ma, NW-striking faulting in 0.60 Ma and normal faulting in 0.024 Ma in the Shuanghu basin. | WU Zhenhan JIANG Wan Peter Blisniuk BI Siwen ZHANG Shukun Olaf Kuchel MAO Yi | 1999 | Acta Geologica Sinica(English Edition)1999，73，3： | 6 |
| 7 | Complement C7 is a novel risk gene for Alzheimer's disease in Han Chinese显示文摘Alzheimer's disease is the most common neurodegenerative disease,and has a high level of genetic heritability and population heterogeneity.In this study,we performed the whole-exome sequencing of Han Chinese patients with familial and/or early-onset Alzheimer's disease,followed by independent validation,imaging analysis and function characterization.We identified an exome-wide significant rare missense variant rs3792646(p.K420Q)in the C7 gene in the discovery stage(P=1.09×10^(-6),odds ratio=7.853)and confirmed the association in different cohorts and a combined sample(1615 cases and 2832 controls,P_(combined)=2.99×10^(-7),odds ratio=1.930).The risk allele was associated with decreased hippocampal volume and poorer working memory performance in early adulthood,thus resulting in an earlier age of disease onset.Overexpression of the mutant p.K420Q disturbed cell viability,immune activation and β-amyloid processing.Electrophysiological analyses showed that the mutant p.K420Q impairs the inhibitory effect of wild type C7 on the excitatory synaptic transmission in pyramidal neurons.These findings suggested that C7 is a novel risk gene for Alzheimer’s disease in Han Chinese. | Deng-Feng Zhang Yu Fan Min Xu Guihong Wang Dong Wang Jin Li Li-Li Kong Hejiang Zhou Rongcan Luo Rui Bi Yong Wu Guo-Dong Li Ming Li Xiong-Jian Luo Hong-Yan Jiang Liwen Tan Chunjiu Zhong Yiru Fang Chen Zhang Nengyin Sheng Tianzi Jiang Yong-Gang Yao | 2019 | National Science Review2019，6，2： | 6 |
| 8 | CFD simulation of fluidization quality in the three-dimensional fluidized bed显示文摘Multiphase computational fluid dynamics(CFD)has become an alternative method to experimental investigation for predicting the fluid dynamics in gas-solid fluidized beds.The model of Brandani and Zhang,which contains additional terms in both the gas-and solid-phase momentum equations,is employed to explore homogeneous fluidization of Geldart type A particles and bubbling fluidization of Geldart type B particles in three-dimensional gas-fluidized beds.In this model,only a correlation for drag force is necessary to close the governing equations.Two kinds of solids,i.e.,fine alumina powder(dp=60 lm and qp=1500 kg/m3)and sand(dp=610 lm and qp=2500 kg/m3),are numerically simulated in a rectangular duct of 0.2 m(long)0.2 m(wide)0.5 m(high)size.The results show good agreement with the classic theory of Geldart. | Kai Zhang Stefano Brandani Jicheng. Bi Jianchun Jiang | 2008 | Progress in Natural Science:Materials International2008，18，6： | 5 |
| 9 | Smoking and Its Relation to Metabolic Status among Chinese Adults: Analysis of a Nationwide Survey显示文摘Objective To update the estimated prevalence rates of smoking and examine major metabolic diseases associated with smoking status in Chinese adults. Methods Using a complex, multistage, probability sampling design, we recruited a nationally representative sample of 98,658 Chinese adults aged ≥18 years in 2010. Information on current, former, never, and passive smoking status was obtained using a standard questionnaire. All estimates were weighted to represent the overall Chinese adult population. Results The estimated proportion of current smokers was 28.3% for Chinese adults aged ≥18 years. The corresponding values of former and passive smokers were 5.1% and 21.4%, respectively. Additionally, former smokers were found to have a less favorable metabolic risk profile among all categories of smoking status in both men and women. The prevalence of metabolic diseases such as diabetes and hypertension also increased with a greater number of smoking pack-years in men. Conclusion The prevalences of current smoking and passive smoking remain high in Chinese adults. | DING Lin XU Yu WANG Li Min JIANG Yong ZHANG Mei LI Yi Chong LU Jie Li XU Min WANG Tian Ge LI Mian ZHAO Zhi Yun DAI Meng WANG Wei Qing ZHAO Wen Hua WANG Lin Hong BI Yu Fang NING Guang 无 | 2016 | Biomedical and Environmental Sciences2016，29，9： | 5 |
| 10 | Engineered trimeric ACE2 binds viral spike protein and locks it in'Thfee-up'conformation to potently inhibit SARS-CoV-2 infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in a severe global pandemic Following SARS-CoV,SARS-CoV-2 is yet another emerge nt beta-coronavirus threate ning human health.1 However,seventeen years after the SARS pandemic,no targeted vaccines or therapeutics have been approved for SARS,while some of them might have held promise for treating COVID-19.Many neutralizing antibodies against SARS-CoV-2 are currently being developed.However,RNA viruses are known to have high mutation rates. | Liang Guo Wenwen Bi Xinling Wang Wei Xu Renhong Yan Yuanyuan Zhang Kai Zhao Yaning Li Mingfeng Zhang Xia Cai Shibo Jiang Youhua Xie Qiang Zhou Lu Lu Bobo Dang | 2021 | Cell Research2021，31，1： | 5 |
| 11 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 12 | Cost-benefit analysis of China’s Action Plan for Air Pollution Prevention and Control显示文摘China’s rapid economic growth has caused severe air pollution and public health problems.Therefore,the Chinese government launched the Action Plan for Air Pollution Prevention and Control(hereinafter referred to as the“Air Plan”)in 2013-2017 to improve air quality and safeguard public health.In this study,an analytical framework for a cost-benefit analysis applicable to China was constructed,and the costs and benefits of the implementation of the“Air Plan”in 30 cities and provinces in China from 2013 to 2017 were evaluated.Results show that the total cost of implementation of the“Air Plan”is 1.6511 trillion RMB.The benefits of air quality improvement were determined to be 2.4691 trillion RMB through the willingness-to-pay method to calculate the economic loss of premature deaths.The net benefit related to the implementation of the“Air Plan”was 818 billion RMB.The public health benefit of air quality improvement was 1.5 times the cost of the nationwide implementation of the“Air Plan”.At the provincial level,net benefits that reach 279.3 billion RMB were the highest in Guangdong,whereas the benefit-cost ratio,where the benefit was 5.5 times the cost,was the highest in Fujian.Estimations in this study can serve as a reference for China in formulating similar environmental policies and implementing the “3-year Plan to Defend the Blue Sky”.In addition,these estimations have practical significance for advancing the long-term effective mechanisms of the cost-benefit analysis of China5s environmental policies. | Jing ZHANG Hongqiang JIANG Wei ZHANG Guoxia MA Yanchao WANG Yaling LU Xi HU Jia ZHOU Fei PENG Jun BI Jinnan WANG | 2019 | Frontiers of Engineering Management2019，6，4： | 4 |
| 13 | Influence of acupuncture with exercise training on learning and memory functions, as well as microtubule-associated protein-2 and synaptophysin expression in the hippocampal CA3 region, in a rat model of cerebral infarction显示文摘The present study was designed to determine microtubule-associated protein-2 and synaptophysin expression in the hippocampal CA3 region in a rat model of middle cerebral artery occlusion. The rats were treated with acupuncture at Baihui (GV 20), Qubin (GB 7), and Qianding (GV 21) points, in addition to exercise training. Results were compared with rats undergoing exercise training only. The Y-maze method and immunohistochemistry revealed decreased error frequency of passing through Y-maze, as well as significantly increased microtubule-associated protein-2 and synaptophysin expression, in the acupuncture with exercise training group compared with the model and exercise training groups after 5 weeks. Microtubule-associated protein-2 and synaptophysin expressions negatively correlated with error frequency of passing through the Y-maze. These results suggested that acupuncture combined with exercise training improved learning and memory functions in a rat model of cerebral infarction. The mechanisms of action were hypothesized to be associated with dendritic or synaptic plasticity in the ipsilateral hippocampal CA3 region. | Wei Jiang Liubing Li Min Yang Yanzhen Bi Kehui Hu Peng Zhang Yixin Shen Qian Yu | 2011 | Neural Regeneration Research2011，6，27： | 4 |
| 14 | LiPO_(2)F_(2) electrolyte additive for high-performance Li-rich cathode material显示文摘Li-rich layered oxide cathodes have received considerable attention because of the high operating potential and specific capacity. However, the structural instability and parasitic reactions at high potential cause severe degradation of the electrochemical performance. In our studies, the cycling stability of Li_(1.14)Ni_(0.133)Co_(0.133)Mn_(0.544)O_(2) cathode is improved with LiPO_(2)F_(2) electrolyte additive. After 500 cycles, the capacity retention is increased from 53.6% to 85% at 3 C by LiPO_(2)F_(2) modification. This performance is mainly attributed to the enhanced interfacial stability of the Li-rich cathode. Based on systematic characterization, LiPO_(2)F_(2) additive was found to promote a stable interface film on the cathode surface during the cycling and mitigates the interfacial side reactions. This study provides new insights for improving high-potential Li-rich layered oxide batteries. | Bing Jiang Jingru Li Bi Luo Qizhang Yan Hao Li Lehao Liu Lihua Chu Yingfeng Li Qiaobao Zhang Meicheng Li | 2021 | Journal of Energy Chemistry2021，30，9： | 3 |
| 15 | Synthesis of poly[methyl(3,3,3-trifluoropropyl)siloxane]-b-poly(ethylene oxide) block copolymers显示文摘一系列新 amphiphilic poly [甲基(3,3,3-trifluoropropyl ) siloxane ]-b-poly(ethylene 氧化物)(PMTFPS-b-PEO ) 把钓饵轻轻放进水里有到吸水的片断的恐水病的片断的不同比率的锁共聚物被联合结束功能的 PMTFPS 和 PEO 人聚合物的反应准备。共聚物被显示由象胶化浸透层析(GPC ) 和 1 H-nudear 磁性的回声(1 H-NMR ) 。 | Xiao-li ZHAN Bi CHEN Qing-hua ZHANG Ling-min YI Bo JIANG Feng-qiu CHEN | 2008 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2008，9，9： | 3 |
| 16 | Effect of Zn, Cu and Ni addition on microstructure and mechanical properties of ascast Mg-Dy alloys显示文摘This paper presents some research information on the effects of Zn, Cu and Ni on the microstructure and mechanical properties of as-cast Mg-2Dy(at.%) alloys. The Mg-2Dy alloy is composed of α-Mg and Mg24Dy5 phases. With the addition of 0.5at.%Zn, 0.5at.%Cu and 0.5at.%Ni, respectively, besides α-Mg, the long period stacking order(LPSO) phases containing Zn, Cu, and Ni precipitated in the α-Mg interdentritic boundary. The addition of Ni effectively refined the dendrite arm spacing. The as-cast Mg-2Dy-0.5Ni alloy exhibited the best tensile strengths and elongation. The better mechanical properties were mainly attributed to small secondry dendrite arm spacing(SDAS) and high volume fraction of LPSO phases. | Guang-li Bi Xiao-mei Luo Jing Jiang Yong-gang Zhang Jian-ji Xu Jie-ming Chen Yuan-dong Li Ying Ma | 2016 | China Foundry2016，13，1： | 3 |
| 17 | Surface Integrity of Ultrasonically-Assisted Milled Ti6Al4V Alloy Manufactured by Selective Laser Melting显示文摘The Ti6Al4V parts produced by the existing selective laser melting(SLM)are mainly confronted with poor surface finish and inevitable interior defects,which substantially deteriorates the mechanical properties and performances of the parts.In this regard,ultrasonically-assisted machining(UAM)technique is commonly introduced to improve the machining quality due to its merits in increasing tool life and reducing cutting force.However,most of the previous studies focus on the performance of UAM with ultrasonic vibrations applied in the tangential and feed directions,whereas few of them on the impact of ultrasonic vibration along the vertical direction.In this study,the effects of feed rate on surface integrity in ultrasonically-assisted vertical milling(UAVM)of the Ti6Al4V alloy manufactured by SLM were systemically investigated compared with the conventional machining(CM)method.The results revealed that the milling forces in UAVM showed a lower amplitude than that in CM due to the intermittent cutting style.The surface roughness values of the parts produced by UAVM were generally greater than that by CM owing to the extra sinusoidal vibration textures induced by the milling cutter.Moreover,the extra vertical ultrasonic vibration in UAVM was beneficial to suppressing machining chatter.As feed rate increased,surface microhardness and thickness of the plastic deformation zone in CM raised due to more intensive plastic deformation,while these two material properties in UAVM were reduced owing to the mitigated impact effect by the high-frequency vibration of the milling cutter.Therefore,the improved surface microhardness and reduced thickness of the subsurface deformation layer in UAVM were ascribed to the vertical high-frequency impact of the milling cutter in UAVM.In general,the results of this study provided an in-depth understanding in UAVM of Ti6Al4V parts manufactured by SLM. | Sai Guo Wei Du Qinghong Jiang Zhigang Dong Bi Zhang | 2021 | Chinese Journal of Mechanical Engineering2021，34，4： | 2 |
| 18 | Double-peak ageing behavior of Mg–2Dy–0.5Zn alloy显示文摘 | Guangli Bi Daqing Fang Lei Zhao Qingxin Zhang Jianshe Lian Qing Jiang Zhonghao Jiang | 2011 | Journal of Alloys and Compounds2011，，32： | 2 |
| 19 | Recent Progress in Atmospheric Chemistry Research in China: Establishing a Theoretical Framework for the “Air Pollution Complex”显示文摘Atmospheric chemistry research has been growing rapidly in China in the last 25 years since the concept of the“air pollution complex”was first proposed by Professor Xiaoyan TANG in 1997.For papers published in 2021 on air pollution(only papers included in the Web of Science Core Collection database were considered),more than 24000 papers were authored or co-authored by scientists working in China.In this paper,we review a limited number of representative and significant studies on atmospheric chemistry in China in the last few years,including studies on(1)sources and emission inventories,(2)atmospheric chemical processes,(3)interactions of air pollution with meteorology,weather and climate,(4)interactions between the biosphere and atmosphere,and(5)data assimilation.The intention was not to provide a complete review of all progress made in the last few years,but rather to serve as a starting point for learning more about atmospheric chemistry research in China.The advances reviewed in this paper have enabled a theoretical framework for the air pollution complex to be established,provided robust scientific support to highly successful air pollution control policies in China,and created great opportunities in education,training,and career development for many graduate students and young scientists.This paper further highlights that developing and low-income countries that are heavily affected by air pollution can benefit from these research advances,whilst at the same time acknowledging that many challenges and opportunities still remain in atmospheric chemistry research in China,to hopefully be addressed over the next few decades. | Tong ZHU Mingjin TANG Meng GAO Xinhui BI Junji CAO Huizheng CHE Jianmin CHEN Aijun DING Pingqing FU Jian GAO Yang GAO Maofa GE Xinlei GE Zhiwei HAN Hong HE Ru-Jin HUANG Xin HUANG Hong LIAO Cheng LIU Huan LIU Jianguo LIU Shaw Chen LIU Keding LU Qingxin MA Wei NIE Min SHAO Yu SONG Yele SUN Xiao TANG Tao WANG Tijian WANG Weigang WANG Xuemei WANG Zifa WANG Yan YIN Qiang ZHANG Weijun ZHANG Yanlin ZHANG Yunhong ZHANG Yu ZHAO Mei ZHENG Bin ZHU Jiang ZHU | 2023 | Advances in Atmospheric Sciences2023，40，8： | 2 |
| 20 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
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