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| 1 | The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice显示文摘动脉粥样硬化(作为) 疾病被多重因素导致,包括基因、环境的元素。现在的学习的目的是在致病上调查高胆固醇,高蛋氨酸食谱,和 apolipoprotein E 缺乏(ApoE/) 的全面效果作为。ApoE/ 老鼠用高胆固醇和蛋氨酸饮食被喂 15 个星期导致 hyperlipidemia 和 hyperhomocysteinemia。genomic DNA (gDNA ) 和 B1 的 methylation 层次在大动脉的纸巾的重复元素被两 methylation 依赖的限制分析测量并且嵌套 methylation 特定的聚合酶链反应(PCR ) 。Methylation 顺序偏爱模式是由有限制 endonuclease 消化的 DNA 接受甲基的能力的 assayed。DNA methyltransferase-1 的 mRNA 表示, 3 (DNMT1, 3 ) 被即时 PCR 检测。S-adenosylmethionine (SAM ) 和 S-adenosylhomocysteine (SAH ) 的集中被高效的液体层析决定。结果显示出 gDNA 和 B1 的 hypomethylation 重复元素。DNMT1 的 mRNA 表示被减少。SAM, SAH,和 SAM/SAH 比率的层次被增加。动脉粥样硬化患者损害区域强烈与风险因素相关。DNA demethylation 的分发被喜欢而不是 non-CpG 岛,它可以在 DNA 正直和 genomic 不稳定性上建议 hypomethylation 的主要影响。总的来说,我们的数据不含糊地证明高胆固醇,高蛋氨酸食谱,和 ApoE/ 的全面角色不与一个单个风险因素的角色一致地一致。DNA methylation 模式在这是相当复杂的并且取决于基因背景和许多深奥风险因素。 | Yideng Jiang Huiping Zhang Tao Sun Ju Wang Weiwei Sun Huihui Gong Binbin Yang Yingkang Shi Jun Wei | 2012 | Acta Biochimica et Biophysica Sinica2012，44，10： | 16 |
| 2 | Ethylene oligomerization by novel iron(Ⅱ) diimine complexes/MAO显示文摘Two novel Fe(Ⅱ) diimine complexes have been synthesized. In combination with MAO, they generate active catalytic systems that oligomerize ethylene with both high catalytic activity and high selectivity for a-olefins. The effects of substituents on the aryl ring, reaction temperatures and molar ratios of Al/Fe on catalytic activity and product distribution are studied. | WANG Hang, YAN Weidong, JIANG Tao, LIU Binbin, XU Wenqing, MA Jianjiang & HU YouliangState Key Laboratory of Engineering Plastics, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China Graduate Student of | 2002 | Chinese Science Bulletin2002，47，19： | 8 |
| 3 | Effect of nitrogen on corrosion behaviour of a novel high nitrogen medium-entropy alloy CrCoNiN manufactured by pressurized metallurgy显示文摘A novel high nitrogen medium-entropy alloy CrCoNiN, which had higher strength and slightly lower ductility than CrCoNi alloy, was successfully manufactured by pressurized metallurgy. The microstructure and corrosion behaviour were investigated by microscopic, electrochemical and spectroscopic methods.The results indicated that nitrogen existed in the form of Cr_2N precipitates and uniformly distributed N atoms, and nitrogen alloying significantly refined the grain size. Besides, nitrogen enriched on the outmost surface of passive film and metal/film interface as ammonia(NH-_3 and NH_4^+) and CrN, respectively. The significant improvement of corrosion resistance of CrCoNiN was attributed to the lower metastable pitting susceptibility together with thicker, less defective and more compact passive film. | Hao Feng Huabing Li Xiaolei Wu Zhouhua Jiang Si Zhao Tao Zhang Dake Xu Shucai Zhang Hongchun Zhu Binbin Zhang Muxin Yang | 2018 | Journal of Materials Science & Technology2018，34，10： | 8 |
| 4 | Dark matter direct search sensitivity of the PandaX-4T experiment显示文摘The Panda X-4T experiment, a 4-ton scale dark matter direct detection experiment, is being planned at the China Jinping Underground Laboratory. In this paper we present a simulation study of the expected background in this experiment. In a 2.8-ton fiducial mass and the signal region between 1-10 keV electron equivalent energy, the total electron recoil background is found to be 4.9 × 10^(-5) kg^(-1) d^(-1) keV^(-1). The nuclear recoil background in the same region is 2.8 × 10^(-7) kg^(-1) d^(-1) keV^(-1). With an exposure of 5.6 ton-years, the sensitivity of Panda X-4 T could reach a minimum spin-independent dark matter-nucleon cross section of 6 × 10^(-48) cm^2 at a dark matter mass of 40 Ge V/c^2. | HongGuang Zhang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui BinBin Dong DeQing Fang ChangBo Fu Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo ZhiFan Guo Ke Han ChangDa He ShengMing He Di Huang XingTao Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju ShaoLi Li Yao Li Heng Lin HuaXuan Liu JiangLai Liu YuGang Ma YaJun Mao KaiXiang Ni JinHua Ning XiangXiang Ren Fang Shi AnDi Tan AnQing Wang Cheng Wang HongWei Wang Meng Wang QiuHong Wang SiGuang Wang XiuLi Wang XuMing Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu JuMin Yuan JianFeng Yue Dan Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，3： | 6 |
| 5 | Abnormal Metabolic Connectivity in Rats at the Acute Stage of Ischemic Stroke显示文摘Stroke at the acute stage is a major cause of disability in adults, and is associated with dysfunction of brain networks. However, the mechanisms underlying changes in brain connectivity in stroke are far from fully elucidated. In the present study, we investigated brain metabolism and metabolic connectivity in a rat ischemic stroke model of middle cerebral artery occlusion(MCAO)at the acute stage using18 F-fluorodeoxyglucose positron emission tomography. Voxel-wise analysis showed decreased metabolism mainly in the ipsilesional hemisphere, and increased metabolism mainly in the contralesional cerebellum. We used further metabolic connectivity analysis to explore the brain metabolic network in MCAO.Compared to sham controls, rats with MCAO showed most significantly reduced nodal and local efficiency in the ipsilesional striatum. In addition, the MCAO group showed decreased metabolic central connection of the ipsilesional striatum with the ipsilesional cerebellum, ipsilesional hippocampus, and bilateral hypothalamus. Taken together,the present study demonstrated abnormal metabolic connectivity in rats at the acute stage of ischemic stroke, which might provide insight into clinical research. | Shengxiang Liang Xiaofeng Jiang Qingqing Zhang Shaofeng Duan Tianhao Zhang Qi Huang Xi Sun Hua Liu Jie Dong Weilin Liu Jing Tao Shujun Zhao Binbin Nie Lidian Chens Baoci Shan | 2018 | Neuroscience Bulletin2018，34，5： | 5 |
| 6 | Ameliorating effects of Inonotus obliquus on high fat diet-induced obese rats显示文摘根据从的数据,将在在一年 2030 的世界上有 21.6 亿过重和 11.2 亿个肥胖的个人[1 ] ,它提起多重疾病的风险例如高血压,癌症的糖尿病,心血管的疾病,和几种类型[2,3 ] 。肥胖被看作新陈代谢的混乱,它被高精力吸入主要导致。在哺乳动物,过量精力首先在脂肪质的织物作为 triglyceride (TG ) 被存储。在过去的十年,调整 adipogenesis 的过程的众多的分子很好被记录了。Peroxisome 激活 proliferator 的受体(PPAR-) 为脂肪质的织物的累积被要求并且贡献肥胖[4 ] 。甾醇规章的元素绑定蛋白质(SREBP ) 作为激活胆固醇和丰满的酸合成的全部节目的抄写因素的一个家庭被识别了[5 ] 。Glyceraldehydes 3 磷酸盐 acyltransferase (GPAT ) 和 diacylglycerol acyltransferase (DGAT ) 广泛地在哺乳动物的纸巾被表示并且催化第一并且在 TG 合成的最后的步,分别地[6 ] 。因此,这些分子可以是为肥胖和类脂化合物新陈代谢的评估的大目标。最近,阳光等。[7 ] 证明了在糖尿病的老鼠的类脂化合物的浆液层次显著地与 Inonotus obliquus 的文化肉汤的干燥的事在 3 星期的治疗以后被减少。李和 Hyun [8 ] 证明水摘录从我。obliquus 减少了高脂肪的饮食的胖重量喂的肥胖的老鼠。因此,我们对什么进一步感兴趣,是怎么能我。obliquus 摘录影响类脂化合物新陈代谢并且什么是位于这反肥胖效果下面的可能的机制。在现在的学习,我们造了一个高脂肪的导致食谱的老鼠模型。 | Tao Wu Qingyu Shu Kai Yang Xiaoxian Xie Xia Wang Yangling Wang Anqi Guo Nate Y-uan Binggong Zhao Binbin Chi QiaobeiWu Zhengwei Fu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，9： | 4 |
| 7 | Stability and bifurcation control of a neuron system under a novel fractional-order PD controller显示文摘In this paper, we address the problem of bifurcation control for a delayed neuron system. By introducing a new fractional-order Proportional-Derivative(PD) feedback controller, this paper aims to control the stability and Hopf bifurcation through adjusting the control gain parameters. The order chosen in PD controller is different with that of the integer-order neuron system. Sufficient conditions for guaranteeing the stability and generating Hopf bifurcation are constructed for the controlled neuron system. Finally,numerical simulation results are illustrated to verify our theoretical derivations and the relationships between the onset of the Hopf bifurcation and the gain parameters are obtained. | SHI Shuo XIAO Min RONG LiNa ZHENG WeiXing TAO BinBin CHENG ZunShui XU FengYu | 2019 | Science China(Technological Sciences)2019，62，12： | 3 |
| 8 | Understanding the Percolation Effect in Triboelectric Nanogenerator with Conductive Intermediate Layer显示文摘Introducing the conductive intermediate layer into a triboelectric nanogenerator(TENG)has been proved as an efficient way to enhance the surface charge density that is attributed to the enhancement of the dielectric permittivity.However,far too little attention has been paid to the companion percolation,another key element to affect the output.Here,the TENG with MXeneembedded polyvinylidene fluoride(PVDF)composite film is fabricated,and the dependence of the output capability on the MXene loading is investigated experimentally and theoretically.Specifically,the surface charge density mainly depends on the dielectric permittivity at lower MXene loadings,and in contrast,the percolation becomes the degrading factor with the further increase of the conductive loadings.At the balance between the dielectric and percolation properties,the surface charge density of the MXene-modified TENG obtained 350%enhancement compared to that with the pure PVDF.This work shed new light on understanding the dielectric and percolation effect in TENG,which renders a universal strategy for the high-performance triboelectronics. | Binbin Zhang Guo Tian Da Xiong Tao Yang Fengjun Chun Shen Zhong Zhiming Lin Wen Li Weiqing Yang | 2021 | Research2021，，1： | 2 |
| 9 | Synthesis of cyclic carbonates and dimethyl carbonate using CO_(2) as a building block catalyzed by MOF-5/KI and MOF-5/KI/K_(2)CO_(3)显示文摘The synthesis of cyclic carbonates or dimethyl carbonate(DMC)using CO_(2) as a building block is a very interesting topic.In this work,we found that the metalorganic framework-5(MOF-5)/KI was an active and a selective catalytic system for the synthesis of cyclic carbonates from CO_(2) and epoxides,and MOF-5/KI/K_(2)CO_(3) was efficient for the preparation of DMC from CO_(2),propylene,and methanol by a sequential route.The impacts of temperature,pressure,and reaction time length on the reactions were investigated,and the mechanism of the reactions is proposed on the basis of the experimental results. | Jinliang SONG Binbin ZHANG Tao JIANG Guanying YANG Buxing HAN | 2011 | Frontiers of Chemistry in China2011，6，1： | 2 |
| 10 | Study on Carbonation Damage Constitutive Curve and Microscopic Damage Mechanism of Tailing Recycled Concrete显示文摘To improve the resource utilization of recycled aggregate concrete(RAC)and make use of the unique pozzolanic activation characteristics of iron ore tailing(IOT),the constitutive curves of tailing recycled concrete(TRC)before and after carbonization were analyzed theoretically,experimentally and microscopically.Firstly,according to the experimental data,the damage constitutive and related damage parameters of TRC were theoretically established by Weibull probability distribution function.Secondly,the comprehensive damage parameter b under different working conditions was studied.Finally,the damage mechanism was formed by EDS and SEM.The results showed that the damage constitutive model based on Weibull probability distribution function was in good agreement with the experimental results.Under each carbonization period,the b first decreased and then rose with the increase of tailings content.When its content was 30%,the b values of TRC were minimized,which were 22.14%,20.99%,25.39%lower than those of NAC,and 41.09%,34.89%,35.44%lower than those of RAC,indicating that IOT had a relatively good optimization effect on the constitutive curve of RAC.The microscopic analysis results also proved that the IOT addition with a proper amount would improve the matrix structure of RAC and increased its compactness,but when the content was higher,it would also cause harmful cracks in its matrix structure and reduced its density.Therefore,the optimal tailing content was about 30%.This paper provided a new method for damage constitutive calculation and analysis of TRC before and after carbonization. | Tao Li Sheliang Wang Fan Xu Binbin Li Bin Dang Meng Zhan Zhiqi Wang | 2021 | Journal of Renewable Materials2021，9，8： | 2 |
| 11 | Revealing the linguistic and geographical disparities of public awareness to Covid-19 outbreak through social media显示文摘The Covid-19 has presented an unprecedented challenge to public health worldwide.However,residents in different countries showed diverse levels of Covid-19 awareness during the outbreak and suffered from uneven health impacts.This study analyzed the global Twitter data from January 1st to June 30th,2020,to answer two research questions.What are the linguistic and geographical disparities of public awareness in the Covid-19 outbreak period reflected on social media?Does significant association exist between the changing Covid-19 awareness and the pandemic outbreak?We established a Twitter data mining framework calculating the Ratio index to quantify and track awareness.The lag correlations between awareness and health impacts were examined at global and country levels.Results show that users presenting the highest Covid-19 awareness were mainly those tweeting in the official languages of India and Bangladesh.Asian countries showed more disparities in awareness than European countries,and awareness in Eastern Europe was higher than in central Europe.Finally,the Ratio index had high correlations with global mortality rate,global case fatality ratio,and country-level mortality rate,with 21-31,35-42,and 13–18 leading days,respectively.This study yields timely insights into social media use in understanding human behaviors for public health research. | Binbin Lin Lei Zou Nick Duffield Ali Mostafavi Heng Cai Bing Zhou Jian Tao Mingzheng Yang Debayan Mandal Joynal Abedin | 2022 | International Journal of Digital Earth2022，15，1： | 2 |
| 12 | Highly efficient synthesis of cyclic carbonates from CO 2 and epoxides catalyzed by KI/lecithin显示文摘 | Jinliang Song Binbin Zhang Peng Zhang Jun Ma Jinli Liu Honglei Fan Tao Jiang Buxing Han | 2011 | Catalysis Today2011，，1： | 1 |
| 13 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 14 | A novel 5- DOF fully parallel manipulator and its kinematic optimi- zation 显示文摘 | Song Yimin Lian Binbin Sun Tao | 2014 | ASME Trans Journal of Mechanisms and Ro- botics2014，6，： | 1 |
| 15 | A Survey of Mathematical Tools in Topology and Performance Integrated Modeling and Design of Robotic Mechanism显示文摘Topology and performance are the two main topics dealt in the development of robotic mechanisms.However,it is still a challenge to connect them by integrating the modeling and design process of both parts in a unified frame.As the properties associated with topology and performance,finite motion and instantaneous motion of the robot play key roles in the procedure.On the purpose of providing a fundamental preparation for integrated modeling and design,this paper carries out a review on the existing unified mathematic frameworks for motion description and computation,involving matrix Lie group and Lie algebra,dual quaternion and pure dual quaternion,finite screw and instantaneous screw.Besides the application in robotics,the review of the work from these mathematicians concentrates on the description,composition and intersection operations of the finite and instantaneous motions,especially on the exponential-differential maps which connect the two sides.Furthermore,an in-depth discussion is worked out by investigating the algebraical relationship among these methods and their further progress in integrated robotic development.The presented review offers insightful investigation to the motion description and computation,and therefore would help designers to choose appropriate mathematical tool in the integrated design and modeling and design of mechanisms and robots. | Xinming Huo Shuofei Yang Binbin Lian Tao Sun Yimin Song | 2020 | Chinese Journal of Mechanical Engineering2020，33，4： | 1 |
| 16 | Establishment of a proteomic profile associated with gonocyte and spermatogonial stem cell maturation and differentiation in neonatal mice显示文摘 | Bo Zheng Quan Zhou Yueshuai Guo Binbin Shao Tao Zhou Lei Wang Zuomin Zhou Jiahao Sha Xuejiang Guo Xiaoyan Huang | 2014 | Proteomics (-)2014，，2： | 1 |
| 17 | Dental caries in fluorine exposure areas in China显示文摘 | Wang Binbin Zheng Baoshan Wang Hongying Ping Yakun Tao Yuehua | 2005 | Environmental Geochemistry and Health2005，，4： | 1 |
| 18 | Improving dynamics of integer-order small-world network models under fractional-order PD control显示文摘The optimal control of dynamics is a popular topic for small-world networks. In this paper, we address the problem of improving the behavior of Hopf bifurcations in an integer-order model of small-world networks. In this study, the time delay is used as the bifurcation parameter. We add a fractional-order proportional-derivative(PD) scheme to an integer-order Newman-Watts(N-W) small-world model to better control the Hopf bifurcation of the model. The most important contribution of this paper involves obtaining the stability of the system and the variation of the conditions of the Hopf bifurcation after a fractional PD controller is added to the integer-order small-world model. The results demonstrate that the designed PD controller can be used to restrain or promote the occurrence of Hopf bifurcations by setting appropriate parameters. We also describe several simulations to verify our research results. | Huaifei WANG Min XIAO Binbin TAO Fengyu XU Zhengxin WANG Chengdai HUANG Jianlong QIU | 2020 | Science China(Information Sciences)2020，63，1： | 1 |
| 19 | A linear-hyperbranched supramolecular amphiphile and its self-assembly into vesicles with great ductility显示文摘 | Tao Wei Liu Yong Jiang Binbin | 2012 | Journal of the American Chemical Society2012，134，： | 1 |
| 20 | The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo显示文摘A biodegradable poly(lactic-co-glycolic acid) loading atorvastatin calcium(AC) nanoparticles(AC-PLGA-NPs) were prepared by probe ultrasonication and evaporation method aiming at improving the oral bioavailability of AC. The effects of experimental parameters, including stabilizer species, stabilizer concentration and pH of aqueous phase, on particle size were also evaluated. The resultant nanoparticles were in spherical shape with an average diameter of 174.7 nm and a narrow particle size distribution. And the drug loading and encapsulation efficiency were about 8% and 71%, respectively. The particle size and polydispersion were almost unchanged in 10 days. The release curves of AC-PLGA-NPs in vitro displaying sustained release characteristics indicated that its release mechanisms were matrix erosion and diffusion. The pharmacokinetic study in vivo revealed that the Cmax and AUC0-∞ of AC-PLGA-NPs in rats were nearly 3.7-fold and 4.7-fold higher than that of pure atorvastatin calcium suspension. Our results demonstrated that the delivery of AC-PLGANPs could be a promising approach for the oral delivery of AC for enhanced bioavailability. | Zhenbao Li Wenhui Tao Dong Zhang Chunnuan Wu Binbin Song Shang Wang Tianyang Wang Mingming Hu Xiaohong Liu Yongjun Wang Yinghua Sun Jin Sun | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，3： | 1 |
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