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| 1 | Factors Associated with Thrombolysis Outcome in Ischemic Stroke Patients with Atrial Fibrillation显示文摘The outcome of early intravenous thrombolysis for ischemic stroke in patients with atrial fibrillation(AF)is worse than that without thrombosis. How to increase the efficacy of intravenous thrombolysis for AF-related ischemic stroke remains largely unknown. In this study, we investigated factors that influence the effect of intravenous thrombolysis in these patients. Our results showed that thrombolysis was independently associated with a favorable outcome(P \ 0.001) and did not influence the mortality of AF-related ischemic stroke, although it increased the risk of hemorrhage within 24 h after treatment. Risk factors for a poor outcome at admission were:heart failure(P = 0.045); high systolic pressure(P = 0.039); high blood glucose(P = 0.030); and a high National Institutes of Health Stroke Scale(NIHSS) score(P \ 0.001). Moreover, high systolic pressure at admission(P = 0.007), high blood glucose(P = 0.027), and a high NIHSS score(P \ 0.001) were independent risk factors for mortality at 3 months. Besides thrombolysis, a high NIHSS score(P = 0.006) and warfarin taken within 48 h before stroke onset(P = 0.032) were also independent risk factors for symptomatic hemorrhage within 24 h after treatment. Ischemic stroke patients with AF benefited from intravenous thrombolysis with recombinant tissue plasminogen activator within 4.5 h after stroke. | Qiuyun Zhao Xiaobo Li Wanli Dong Min Ye Yongjun Cao Meijuan Zhang Qiantao Cheng Junshan Zhou Guofang Chen Ming Yu Shanshan Hong Xiue Wei Bei Wang Guiyun Cui Peng Zhang Hong Ding Rongzhen Xu Yan Chen Yun Xu | 2016 | Neuroscience Bulletin2016，32，2： | 13 |
| 2 | Development and validation of an endoscopic images-based deep learning model for detection with nasopharyngeal malignancies显示文摘Background:Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperpla-sia,the positive rate for malignancy identification during biopsy is low,thus leading to delayed or missed diagnosis for nasopharyngeal malignancies upon initial attempt.Here,we aimed to develop an artificial intelligence tool to detect nasopharyngeal malignancies under endoscopic examination based on deep learning.Methods:An endoscopic images-based nasopharyngeal malignancy detection model(eNPM-DM)consisting of a fully convolutional network based on the inception architecture was developed and fine-tuned using separate training and validation sets for both classification and segmentation.Briefly,a total of 28,966 qualified images were collected.Among these images,27,536 biopsy-proven images from 7951 individuals obtained from January 1st,2008,to December 31st,2016,were split into the training,validation and test sets at a ratio of 7:1:2 using simple randomiza-tion.Additionally,1430 images obtained from January 1st,2017,to March 31st,2017,were used as a prospective test set to compare the performance of the established model against oncologist evaluation.The dice similarity coef-ficient(DSC)was used to evaluate the efficiency of eNPM-DM in automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images,by comparing automatic segmentation with manual segmenta-tion performed by the experts.Results:All images were histopathologically confirmed,and included 5713(19.7%)normal control,19,107(66.0%)nasopharyngeal carcinoma(NPC),335(1.2%)NPC and 3811(13.2%)benign diseases.The eNPM-DM attained an overall accuracy of 88.7%(95%confidence interval(CI)87.8%-89.5%)in detecting malignancies in the test set.In the prospective comparison phase,eNPM-DM outperformed the experts:the overall accuracy was 88.0%(95%CI 86.1%-89.6%)vs.80.5%(95%CI 77.0%-84.0%).The eNPM-DM required less time(40 s vs.110.0±5.8 min)and exhibited encouraging performance in automatic segmentation of nasopharyngeal malignant area from the background,with an average DSC of 0.78±0.24 and 0.75±0.26 in the test and prospective test sets,respectively.Conclusions:The eNPM-DM outperformed oncologist evaluation in diagnostic classification of nasopharyngeal mass into benign versus malignant,and realized automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images. | Chaofeng Li Bingzhong Jing Liangru Ke Bin Li Weixiong Xia Caisheng He Chaonan Qian Chong Zhao Haiqiang Mai Mingyuan Chen Kajia Cao Haoyuan Mo Ling Guo Qiuyan Chen Linquan Tang Wenze Qiu Yahui Yu Hu Liang Xinjun Huang Guoying Liu Wangzhong Li Lin Wang Rui Sun Xiong Zou Shanshan Guo Peiyu Huang Donghua Luo Fang Qiu Yishan Wu Yijun Hua Kuiyuan Liu Shuhui Lv Jingjing Miao Yanqun Xiang Ying Sun Xiang Guo Xing Lv | 2018 | Cancer Communications2018，38，1： | 9 |
| 3 | Distribution and Provenance of Detrital Minerals in Southern Coast of Shandong Peninsula显示文摘Detrital minerals of 137 offshore and 22 river sediment samples collected from Qingdao coastal areas have been analyzed. Four mineral assemblage provinces can be classified by Q-mode cluster analysis. Factor analysis identifies two major factors that account for the total variability in most common minerals: 1) based on the relationship of quartz, hornblende, actinolite, micas, and authigenic pyrite, 41.55% of the variability is related to sediment sources; 2) based on the relationship of epidote, garnet, sphere, and ilmenite, 23.21% can be related to strong hydrodynamic conditions that control transport and sedimentation. By comparing mineral compositions of river waters in the study area, the following four mineral provenances can be identified. The Qingdao-Laoshan nearshore area has a quartz-feldspar-epidote-hornblende-limenite-limonite-sphene assemblage, which is largely attributed to relict sediment and coastal erosion. The Jimo-Haiyang nearshore area has a quartz-feldspar-hornblende-epidote-limonite-mica-actinolite assemblage, derived largely from the Wulong River and Rushan River, and is also affected by the Huanghe River, while the Qianliyan Island area in the deeper offshore area separated by a mud belt has a similar assemblage. The Haiyang-Rushan nearshore area has a quartz-feldspar-hornblende-epidote-micas-limonite assemblage, indicating multiple sources from the Rushan River, the Wulong River, the Huanghe River, and coastal erosion. The central area, located in an eddy center, has a mica-authigenic pyrite-hornblende-quartz-feldspar assemblage, indicating multiple sources dominated by Huanghe River distal sediments. | LIU Jinqing YIN Ping ZHANG Yong SONG Hongying BI Shipu CAO Zhimin LIU Shanshan | 2017 | Journal of Ocean University of China2017，16，5： | 9 |
| 4 | Famitinib in combination with concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 1, open-label, dose-escalation Study显示文摘Background:Famitinib is a tyrosine kinase inhibitor against multiple targets,including vascular endothelial growth factor receptor 2/3,platelet-derived growth factor receptor,and stem cell factor receptor(c-kit).Previous studies have demonstrated anti-tumour activities of famitinib against a wide variety of advanced-stage solid cancers.We aimed to determine the safety and efficacy of famitinib with concurrent chemoradiotherapy(CCRT)in patients with locoregionally advanced nasopharyngeal carcinoma(NPC).We also evaluated the feasibility of contrast-enhanced ultrasound(D-CEUS)as a predictor of early tumour response to famitinib and to correlate functional parameters with clinical efficacy.Methods:The trial was conducted in subjects with stage III or IVa-b NPC using a 3+3 design of escalating fami-tinib doses.Briefly,subjects received 2 weeks of famitinib monotherapy followed by 7 weeks of famitinib plus CCRT.D-CEUS of the neck lymph nodes was performed at day 0,8 and 15 after famitinib was administered before starting concurrent chemoradiotherapy.End points included safety,tolerability and anti-tumour activity.Results:Twenty patients were enrolled(six each for 12.5,16.5 and 20 mg and two for 25 mg).Two patients in the 25 mg cohort developed dose-limiting toxicities,including grade 4 thrombocytopenia and grade 3 hypertension.The most common grade 3/4 adverse events were leukopenia,neutropenia and radiation mucositis.D-CEUS tests showed that more than 60%of patients achieved a perfusion parameter response after 2 weeks taking famitinib alone,and the parameter response was associated with disease improvement.In the famitinib monotherapy stage,three patients(15%)showed partial responses.The complete response rate was 65%at the completion of treatment and 95%3 months after the treatment ended.After a median follow-up of 44 months,the 3-year progression-free survival(PFS)and distant metastasis-free survival were 70%and 75%,respectively.Subjects with a decrease of perfusion parameter response,such as peak intensity decreased at least 30%after 1 week of famitinib treatment,had higher 3-year PFS(90.9%vs.44.4%,95%CI 73.7%-100%vs.11.9%-76.9%,P<0.001)than those with an increase or a reduction of less than 30%.Conclusions:The recommended famitinib dose for phase II trial is 20 mg with CCRT for patients with local advanced NPC.D-CEUS is a reliable and early measure of efficacy for famitinib therapies.Further investigation is required to confirm the effects of famitinib plus chemoradiotherapy. | Qiuyan Chen Linquan Tang Na Liu Feng Han Ling Guo Shanshan Guo Jianwei Wang Huai Liu Yanfang Ye Lu Zhang Liting Liu Pan Wang Yingqin Li Qingmei He Xiaoqun Yang Qingnan Tang Yang Li YuJing Liang XueSong Sun Chuanmiao Xie Yunxian Mo Ying Guo Rui Sun Haoyuan Mo Kajia Cao Xiang Guo Musheng Zeng Haiqiang Mai Jun Ma | 2018 | Cancer Communications2018，38，1： | 6 |
| 5 | Fine-Grained Bulk NiTi Shape Memory Alloy Fabricated by Rapid Solidifcation Process and Its Mechanical Properties and Damping Performance显示文摘A near-equiatomic NiTi shape memory alloy was fabricated by rapid solidification process through vacuum arc melting followed by vacuum suction casting in water-cooled thick copper mold.The rapidly solidified(or suction cast) NiTi alloy shows much finer grains and homogenous microstructure,in particular a uniform distribution of various fine precipitates,compared to the conventional cast one.The resultant alloy also exhibits the homogenous Ni distribution in the matrix of the alloy,allowing the martensitic transformation to take place throughout the NiTi alloy matrix simultaneously and resulting in sharper transformation peaks compared to the conventional cast alloy.Moreover,the suction cast NiTi alloy shows a significant improvement over the conventional cast one,in terms of possessing higher deformation recovery rates and displaying the increased compressive strength and damping capacity by 4% and 20%,respectively. | Hongjie Jiang Shanshan Cao Changbo Ke Xiao Ma Xinping Zhang | 2013 | Journal of Materials Science & Technology2013，29，9： | 6 |
| 6 | Integrating CART Algorithm and Multi-source Remote Sensing Data to Estimate Sub-pixel Impervious Surface Coverage:A Case Study from Beijing Municipality,China显示文摘The sub-pixel impervious surface percentage(SPIS) is the fraction of impervious surface area in one pixel,and it is an important indicator of urbanization.Using remote sensing data,the spatial distribution of SPIS values over large areas can be extracted,and these data are significant for studies of urban climate,environment and hydrology.To develop a stabilized,multi-temporal SPIS estimation method suitable for typical temperate semi-arid climate zones with distinct seasons,an optimal model for estimating SPIS values within Beijing Municipality was built that is based on the classification and regression tree(CART) algorithm.First,models with different input variables for SPIS estimation were built by integrating multi-source remote sensing data with other auxiliary data.The optimal model was selected through the analysis and comparison of the assessed accuracy of these models.Subsequently,multi-temporal SPIS mapping was carried out based on the optimal model.The results are as follows:1) multi-seasonal images and nighttime light(NTL) data are the optimal input variables for SPIS estimation within Beijing Municipality,where the intra-annual variability in vegetation is distinct.The different spectral characteristics in the cultivated land caused by the different farming characteristics and vegetation phenology can be detected by the multi-seasonal images effectively.NLT data can effectively reduce the misestimation caused by the spectral similarity between bare land and impervious surfaces.After testing,the SPIS modeling correlation coefficient(r) is approximately 0.86,the average error(AE) is approximately 12.8%,and the relative error(RE) is approximately 0.39.2) The SPIS results have been divided into areas with high-density impervious cover(70%–100%),medium-density impervious cover(40%–70%),low-density impervious cover(10%–40%) and natural cover(0%–10%).The SPIS model performed better in estimating values for high-density urban areas than other categories.3) Multi-temporal SPIS mapping(1991–2016) was conducted based on the optimized SPIS results for 2005.After testing,AE ranges from 12.7% to 15.2%,RE ranges from 0.39 to 0.46,and r ranges from 0.81 to 0.86.It is demonstrated that the proposed approach for estimating sub-pixel level impervious surface by integrating the CART algorithm and multi-source remote sensing data is feasible and suitable for multi-temporal SPIS mapping of areas with distinct intra-annual variability in vegetation. | HU Deyong CHEN Shanshan QIAO Kun CAO Shisong | 2017 | Chinese Geographical Science2017，27，4： | 5 |
| 7 | Extensive profiling of the expressions of tRNAs and tRNA-derived fragments(tRFs)reveals the complexities of tRNA and tRF populations in plants显示文摘Evidence is emerging that t RNA-derived fragments(t RFs)are regulatory molecules.Studies of t RFs in plants have been based on conventional small RNA sequencing,and focused on profiling of t RF-5 and t RF-3 species.A more comprehensive and quantitative analysis of the entire t RF population is highly necessary.Here,we employ t RNA-seq and YAMAT-seq,and develop a bioinformatics tool to comprehensively profile the expressions of t RNAs and t RFs in plants.We show that in Arabidopsis,approximately half of t RNA genes are extremely weakly expressed,accounting for only 1%of total t RNA abundance,while~12%of t RNA genes contribute to~80%of t RNA abundance.Our t RNA sequencings in various plants reveal that t RNA expression profiles exhibit a cross-species conserved pattern.By characterizing the composition of a highly heterogeneous t RF population,we show that t RNA halves and previously unnoticed 10–16-nt tiny t RFs represent substantial portions.The highly accumulated 13-nt and 16-nt tiny t RFs in Arabidopsis indicate that tiny t RFs are not random t RNA degradation products.Finally,we provide a user-friendly database for displaying the dynamic spatiotemporal expressions of t RNAs and t RFs in the model plants Arabidopsis and rice. | Xuan Ma Chunyan Liu Xiaocong Kong Jing Liu Siju Zhang Shanshan Liang Weijiang Luan Xiaofeng Cao | 2021 | Science China(Life Sciences)2021，64，4： | 5 |
| 8 | Efficacy of Shoushen granule on adenosine triphosphate binding cassette transporter A1, proprotein convertase subtilisin/kexin type 9 and toll-like receptor 4/nuclear factor kappa-B signaling pathway in ApoE-knockout mice显示文摘OBJECTIVE: To evaluate the efficacy of Shoushen granule, prepared with four Chinese medicinals, on the targeted regulation of adenosine triphosphate binding cassette transporter A1(ABCA1) through proprotein convertase subtilisin/kexin type 9(PCSK9) and toll-like receptor 4(TLR4)/nuclear factor kappa-B(NF-κB) signaling pathway to affect atherosclerosis(AS) in ApoE-knockout(ApoE-/-) mice.METHODS: ApoE-/-mice fed with a high-fat diet were used for AS modeling and divided into Model,Shoushen, and Atorvastatin groups. C57 BL/6 J mice at the same age and background strain were included in the Control group. Western blot and immunohistochemistry were used to measure ABCA1, PCSK9, TLR4, and NF-κB protein expression in mouse aortas. Enzyme-linked immuno sorbent assay was used to measure mouse serum tumor necrosis factor-α(TNF-α), interleukin-10(IL-10), monocyte chemoattractant protein 1(MCP-1), and intercellular cell adhesion molecule-1(ICAM-1) expression. Serum lipid profiles and histopathology were also assessed. Shoushen granule were composed of Heshouwu(Radix Polygoni Multiflori) 15 g, Gouqizi(Fructus Lycii) 15 g, Sheng shanzha(Raw Fructus Crataegus Pinnatifidae) 10 g, and Sanqi(Radix Notoginseng) 3 g.RESULTS: ApoE-/-mice fed with a high-fat diet had notable AS lesions, with reduced ABCA1 and IL-10 levels, elevated PCSK9, TLR4, NF-κB, TNF-α, MCP-1,and ICAM-1 expression, and increased total cholesterol(TC) and low density lipoprotein cholesterol(LDL-C) contents. With drug interventions, the areas of AS plaques were significantly reduced,the ABCA1 and IL-10 levels were increase, while the PCSK9, TLR4, NF-κB, TC, and LDL-C contents,and the TNF-α, MCP-1, and ICAM-1 expression were reduced.CONCLUSION: Shoushen granule effectively interfered with AS development by antagonizing the expression of key factors of the PCSK9 and TLR4/NF-κB signaling pathway to upregulate ABCA1 expression. | Li Shanshan Cao Hui Shen Dingzhu Chen Chuan Xing Sanli Dou Fangfang Jia Qingling | 2019 | Journal of Traditional Chinese Medicine2019，39，4： | 4 |
| 9 | The structural characteristics of dietary fibers from Tremella fuciformis and their hypolipidemic effects in mice显示文摘In this study,Tremella fuciformis residues as raw material,dietary fibers from tremella were prepared by multiple enzymes.The structure of dietary fibers from tremella was studied by Fourier transform infrared(FTIR),X-ray diffraction analysis(XRD)and scanning electron microscopy(SEM).We analyzed their lipidlowering properties in vitro(water holding,oil holding swelling cholesterol and sodium cholate binding capacitises)and the hypolipidemic effects in mice.The results showed that tremella dietary fibers presented the infrared absorption spectrum characteristics of polysaccharides and the characteristic diffraction peaks of cellulose type I.SEM results indicated that the surface of insoluble dietary fiber(IDF)was porous,while the soluble dietary fiber(SDF)was relatively compact and spongy.IDF exhibited significantly higher water holding,oil holding,and swelling binding capacities than the corresponding SDF.However,SDF exhibited significantly higher viscosity than IDF.The results showed tremella dietary fibers were significant in swelling,water holding and oil holding,cholesterol and bile acids.In vivo experiment results in mice indicated that SDF has the best effect on hyperlipidemia mice than IDF and total dietary fiber(TDF).SDF showed that the total cholesterol(TC),triglyceride(TG)and low density lipoprotein cholesterol(LDL-C)contents dropped by 28.33%,18.65%,and 48.97%,respectively,while high density lipoprotein cholesterol(HDL-C)content increased by 43.80%.Compared with the high-fat control(HCM)group,the arteriosclerosis index(AI)and liver index(LI)of the SDF group mice showed significant differences,indicating that SDF has a good auxiliary effect of lowering blood lipids.The administration of tremella fibers improved the lipid metabolism disorderly situation of hyperlipidemia mice.These results provide a reference for further research and rational development of T.fuciformis. | Shanshan Zhang Xinle Xu Xu Cao Tingting Liu | 2023 | Food Science and Human Wellness2023，12，2： | 4 |
| 10 | Understanding the spatial representativeness of air quality monitoring network and its application to PM_(2.5)in the China's Mainland显示文摘Air pollution has seriously endangered human health and the natural ecosystem during the last decades.Air quality monitoring stations(AQMS)have played a critical role in providing valuable data sets for recording regional air pollutants.The spatial representativeness of AQMS is a critical parameter when choosing the location of stations and assessing effects on the population to long-term exposure to air pollution.In this paper,we proposed a methodological framework for assessing the spatial representativeness of the regional air quality monitoring network and applied it to ground-based PM_(2.5)observation in the mainland of China.Weighted multidimensional Euclidean distance between each pixel and the stations was used to determine the representativeness of the existing monitoring network.In addition,the K-means clustering method was adopted to improve the spatial representativeness of the existing AQMS.The results showed that there were obvious differences among the representative area of 1820 stations in the mainland of China.The monitoring stations could well represent the PM_(2.5)spatial distribution of the entire region,and the effectively represented area(i.e.the area where the Euclidean distance between the pixels and the stations was lower than the average value)accounted for 67.32%of the total area and covered 93.12%of the population.Forty additional stations were identified in the Northwest,North China,and Northeast regions,which could improve the spatial representativeness by 14.31%. | Ling Su Chanchan Gao Xiaoli Ren Fengying Zhang Shanshan Cao Shiqing Zhang Tida Chen Mengqing Liu Bingchuan Ni Min Liu | 2022 | Geoscience Frontiers2022，13，3： | 3 |
| 11 | Volatiles produced by bacteria alleviate antagonistic effects of one associated fungus on Dendroctonus valens larvae显示文摘Dear Editor,Microbes play important roles in various symbiotic systems(Douglas,2015;Xing et al.,2017;Zhu and Wu,2016;Xu et al.,2016a).In the symbiosis formed by bark beetles and microbial associates,beetles formed symbiotic relationships with some fungi including mutualistic and antagonistic ones(Cheng et al.,2015;Lu et al.,2016;Scott et al.,2008),and these interactions,indirectly affected by a third or even fourth participator in a community context,may change from antagonistic ones to mutualistic ones.For example,associated bacterial volatiles can alleviate antagonistic | Shanshan Wang Fangyuan Zhou Bo Wang Dandan Xu Qingjie Cao Min Lu Jianghua-Sun | 2017 | Science China(Life Sciences)2017，60，8： | 2 |
| 12 | Kilometers Long Graphene-Coated Optical Fibers for Fast Thermal Sensing显示文摘The combination of optical fiber with graphene has greatly expanded the application regimes of fiber optics,from dynamic optical control and ultrafast pulse generation to high precision sensing.However,limited by fabrication,previous graphene-fiber samples are typically limited in the micrometer to centimeter scale,which cannot take the inherent advantage of optical fibers—longdistance optical transmission.Here,we demonstrate kilometers long graphene-coated optical fiber(GCF)based on industrial graphene nanosheets and coating technique.The GCF shows unusually high thermal diffusivity of 24.99 mm^(2) s^(-1) in the axial direction,measured by a thermal imager directly.This enables rapid thermooptical response both in optical fiber Bragg grating sensors at one point(18-fold faster than conventional fiber)and in long-distance distributed fiber sensing systems based on backward Rayleigh scattering in optical fiber(15-fold faster than conventional fiber).This work realizes the industrial-level graphene-fiber production and provides a novel platform for two-dimensional material-based optical fiber sensing applications. | Yiyong Guo Bing Han Junting Du Shanshan Cao Hua Gao Ning An Yiwei Li Shujie An Zengling Ran Yue Lin Wencai Ren Yunjiang Rao Baicheng Yao | 2021 | Research2021，，1： | 2 |
| 13 | RNAi?mediated knockdown of PRL?3 inhibits cell invasion and downregulatesERK 1/2 expression in the human gastric cancer cell line, SGC?7901显示文摘 | Yi Cao Yi Tu Jinhong Mei Zhengrong Li Zhigang Jie Shan Xu Linlin Xu Shanshan Wang Yifeng Xiong | 2013 | Molecular Medicine Reports2013，，6： | 2 |
| 14 | Nonpharmaceutical interventions contribute to the control of COVID-19 in China based on a pairwise model显示文摘Nonpharmaceutical interventions(NPIs),particularly contact tracing isolation and household quarantine,play a vital role in effectively bringing the Coronavirus Disease 2019(COVID-19)under control in China.The pairwise model,has an inherent advantage in characterizing those two NPIs than the classical well-mixed models.Therefore,in this paper,we devised a pairwise epidemic model with NPIs to analyze COVID-19 outbreak in China by using confirmed cases during February 3rde22nd,2020.By explicitly incorporating contact tracing isolation and family clusters caused by household quarantine,our model provided a good fit to the trajectory of COVID-19 infections.We calculated the reproduction number R=1.345(95%CI:1.230-1.460)for Hubei province and R=1.217(95%CI:1.207-1.227)for China(except Hubei).We also estimated the peak time of infections,the epidemic duration and the final size,which are basically consistent with real observation.We indicated by simulation that the traced high-risk contacts from incubated to susceptible decrease under NPIs,regardless of infected cases.The sensitivity analysis showed that reducing the exposure of the susceptible and increasing the clustering coefficient bolster COVID-19 control.With the enforcement of household quarantine,the reproduction number R and the epidemic prevalence declined effectively.Furthermore,we obtained the resumption time of work and production in China(except Hubei)on 10th March and in Hubei at the end of April 2020,respectively,which is broadly in line with the actual time.Our results may provide some potential lessons from China on the control of COVID-19 for other parts of the world. | Xiao-Feng Luo Shanshan Feng Junyuan Yang Xiao-Long Peng Xiaochun Cao Juping Zhang Meiping Yao Huaiping Zhu Michael Y.Li Hao Wang Zhen Jin | 2021 | Infectious Disease Modelling2021，6，1： | 2 |
| 15 | Active canopy sensing of winter wheat nitrogen status: An evaluation of two sensor systems显示文摘 | Qiang Cao Yuxin Miao Guohui Feng Xiaowei Gao Fei Li Bin Liu Shanchao Yue Shanshan Cheng Susan L. Ustin R. Khosla | 2014 | Computers and Electronics in Agriculture2014，，： | 1 |
| 16 | Heterogeneity and influencing factors of marine gravity flow tight sandstone under abnormally high pressure:A case study from the Miocene Huangliu Formation reservoirs in LD10 area,Yinggehai Basin,South China Sea显示文摘The characteristics of reservoir heterogeneity of the marine gravity flow tight sandstone from the Miocene Huangliu Formation under abnormally high pressure setting at LD10 area in Yinggehai Basin are studied,and the influencing factors on reservoir heterogeneity are discussed,based on modular formation dynamics test,thin sections,XRD analysis of clay minerals,scanning electron microscopy,measurement of pore throat image,porosity and permeability,and high pressure Hg injection,as well as the stimulation of burial thermal history.The aim is to elucidate characteristics of the heterogeneity and the evolution process of heterogeneity of the reservoir,and predict the favorable reservoirs distribution.(1)The heterogeneity of the reservoir is mainly controlled by the cement heterogeneity,pore throat heterogeneity,quality of the reservoir heterogeneity,and the diagenesis under an abnormally high pressure setting.(2)The differences in pore-throat structure caused by diagenetic evolution affected the intergranular material heterogeneity and the pore throat heterogeneity,and finally controlled the heterogeneity of reservoir quality.(3)Compared with the reservoir under normal pressure,abnormally high pressure restrains strength of the compaction and cementation and enhances the dissolution of the reservoir to some extent,and abnormally high pressure thus weakening the heterogeneity of the reservoir to a certain degree.The favorable reservoirs are mainly distributed in the gravity flow sand body under the strong overpressure zone in the middle and lower part of Huangliu Formation. | FAN Caiwei CAO Jiangjun LUO Jinglan LI Shanshan WU Shijiu DAI Long HOU Jingxian MAO Qianru | 2021 | Petroleum Exploration and Development2021，48，5： | 1 |
| 17 | Near-infrared light-triggered micelles for fast controlled drug release in deep tissue 显示文摘 | Cao Jie Huang Shanshan Chen Yuqi | 2013 | Biomaterials2013，34，26： | 1 |
| 18 | Shorter alkyl chain in thieno[3,4-c]pyrrole-4,6-dione(TPD)-based large bandgap polymer donors – Yield efficient non-fullerene polymer solar cells显示文摘Typically,conjugated polymers are composed of conjugated backbones and alkyl side chains.In this contribution,a cost-effective strategy of tailoring the length of alkyl side chain is utilized to design highperforming thieno[3,4-c]pyrrole-4,6-dione(TPD)-based large bandgap polymer donors PBDT-BiTPD(Cχ)(χ=48,52,56),in which x represents the alkyl side chain length in term of the total carbon number.A combination of light absorption,device,and morphology examinations make clear that the shorter alkyl side chains yield(i) higher crystallinity and more predominant face-on crystallite orientation in their neat and BHJ blend films,(ii) higher charge mobilities(6.7×10^(-4) cm~2 V^(-1) s^(-1) for C48 vs.3.2×10^(-4) cm~2 V^(-1) s^(-1) for C56),and negligible charge recombination,consequently,(iii) significantly improved fill-factor(FF) and short current(J_(SC)),while almost the same open circuit voltage(V_(OC)) of ca.0.82 V in their corresponding BHJ devices.In parallel,as alkyl side chain lengths decrease from C56 to C48,power conversion efficiencies(PCEs) increased from 7.8% for C56 to 11.1% for C52,and further to14.1% for C48 in their BHJ solar cells made with a narrow bandgap non-fullerene acceptor Y6.This systematic study declares that shortening the side chain,if providing appropriate solubility in device solution processing solvents,is of essential significance for developing high-performing polymer donors and further improving device photovoltaic performance. | Jiaji Zhao Xuelong Huang Qingduan Li Shengjian Liu Ziqiang Fan Di Zhang Shanshan Ma Zhixiong Cao Xuechen Jiao Yue-Peng Cai Fei Huang | 2021 | Journal of Energy Chemistry2021，30，2： | 1 |
| 19 | Sustainable nitrogen- doped porous carbon with high surface areas prepared from gelatin for supercapacitors显示文摘 | Xu Bin Hou Shanshan Cao Gaoping | 2012 | Journal of Materials Chemistry2012，22，19： | 1 |
| 20 | Concentration distribution and assessment of several heavy metals in sediments of west-four Pearl River Estuary显示文摘 | Shanshan Wang Zhimin Cao Dongzhao Lan Zhichang Zheng Guihai Li | 2008 | Environmental Geology2008，，5： | 1 |
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