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| 1 | Fundus artery occlusion caused by cosmetic facial injections显示文摘 | Chen Yanyun Wang Wenying Li Jipeng Yu Yajie Li Lin Lu Ning | 2014 | Chinese Medical Journal2014，，8： | 35 |
| 2 | Enhanced extraction of essential oil from Cinnamomum cassia bark by ultrasound assisted hydrodistillation显示文摘Cinnamon essential oil with many bioactivities is an important raw material for the production of various chemicals,and the conventional hydrodistillation(HD)for cinnamon oil extraction always require a longer extraction time.In this work,ultrasound-assisted hydrodistillation extraction(UAHDE)technique was employed to enhance the extraction efficiency of essential oils from cinnamon barks.The parameters with significant effects on the essential oil extraction efficiency(ultrasound time,ultrasound power,extraction time,liquid–solid ratio)were optimized,and the proposed UAHDE was compared with the conventional HD extraction in terms of the extraction time,extraction yield,and physicochemical properties of extracted oils.Compared to the HD extraction,the UAHDE resulted in a shorter extraction time and a higher extraction yield.Using GC–MS analysis,the UAHDE provided more valuable essential oil with a high content of the vital trans-cinnamaldehyde compounds compared with the HD.Scanning electron micrograph(SEM)confirmed the efficiency of ultrasound irradiation for cinnamon oil extraction.In addition,the analysis of electric consumption and CO_(2) emission shows that the UAHDE process is a more economic and environment-friendly approach.Thus,UAHDE is an efficient and green technology for the cinnamon essential oil extraction,which could improve the quantity and quality of cinnamon oils. | Guanghui Chen Fengrui Sun Shougui Wang Weiwen Wang Jipeng Dong Fei Gao | 2021 | Chinese Journal of Chemical Engineering2021，34，8： | 4 |
| 3 | Proteomics provides individualized options of precision medicine for patients with gastric cancer显示文摘While precision medicine driven by genome sequencing has revolutionized cancer care,such as lung cancer,its impact on gastric cancer(GC)has been minimal.GC patients are routinely treated with chemotherapy,but only a fraction of them receive the clinical benefit.There is an urgent need to develop biomarkers or algorithms to select chemo-sensitive patients or apply targeted therapy.Here,we carried out retrospective analyses of 1,020 formalin-fixed,paraffin-embedded GC surgical resection samples from 5 hospitals and developed a mass spectrometry-based workflow for proteomic subtyping of GC.We identified two proteomic subtypes:the chemo-sensitive group(CSG)and the chemo-insensitive group(CIG)in the discovery set.The 5-year overall survival of CSG was significantly improved in patients who had received adjuvant chemotherapy after surgery compared with those who received surgery only(64.2%vs.49.6%;Cox P-value=0.002),whereas no such improvement was observed in CIG(50.0%vs.58.6%;Cox P-value=0.495).We validated these results in an independent validation set.Further,differential proteome analysis uncovered 9 FDA-approved drugs that may be applicable for targeted therapy of GC.A prospective study is warranted to test these findings for future GC patient care. | Wenwen Huang Dongdong Zhan Yazhuo Li Nairen Zheng Xin Wei Bin Bai Kecheng Zhang Mingwei Liu Xuefei Zhao Xiaotian Ni Xia Xia Jinwen Shi Cheng Zhang Zhihao Lu Jiafu Ji Juan Wang Shiqi Wang Gang Ji Jipeng Li Yongzhan Nie Wenquan Liang Xiaosong Wu Jianxin Cui Yongsheng Meng Feilin Cao Tieliu Shi Weimin Zhu Yi Wang Lin Chen Qingchuan Zhao Hongwei Wang Lin Shen Jun Qin | 2021 | Science China(Life Sciences)2021，64，8： | 3 |
| 4 | Association of systemic inflammation and body mass index with survival in patients with resectable gastric or gastroesophageal junction adenocarcinomas显示文摘Objective:The systemic inflammation index and body mass index(BMI)are easily accessible markers that can predict mortality.However,the prognostic value of the combined use of these two markers remains unclear.The goal of this study was therefore to evaluate the association of these markers with outcomes based on a large cohort of patients with gastric cancer.Methods:A total of 2,542 consecutive patients undergoing radical surgery for gastric or gastroesophageal junction adenocarcinoma between 2009 and 2014 were included.Systemic inflammation was quantified by the preoperative neutrophil-to-lymphocyte ratio(NLR).High systemic inflammation was defined as NLR≥3,and underweight was defined as BMI<18.5 kg/m2.Results:Among 2,542 patients,NLR≥3 and underweight were common[627(25%)and 349(14%),respectively].In the entire cohort,NLR≥3 or underweight independently predicted overall survival(OS)[hazard ratio(HR):1.236,95%confidence interval(95%CI):1.069–1.430;and HR:1.600,95%CI:1.350–1.897,respectively]and recurrence-free survival(RFS)(HR:1.230,95%CI:1.054–1.434;and HR:1.658,95%CI:1.389–1.979,respectively).Patients with both NLR≥3 and underweight(vs.neither)had much worse OS(HR:2.445,95%CI:1.853–3.225)and RFS(HR:2.405,95%CI:1.802–3.209).Furthermore,we observed similar results in subgroup analyses according to pathological stage,age,and postoperative chemotherapy.Conclusions:Our results showed that preoperative elevated NLR and decreased BMI had a significant negative effect on survival.Underweight combined with severe inflammation could enhance prognostication.Taking active therapeutic measures to reduce inflammation and increase nutrition may help improve outcomes. | Xianchun Gao Yanan Pan Weili Han Caie Hu Chenchen Wang Ling Chen Yong Guo Yupeng Shi Yan Pan Huahong Xie Liping Yao Jianjun Yang Jianyong Zheng Xiaohua Li Xiaonan Liu Liu Hong Jipeng Li Mengbin Li Gang Ji Zengshan Li Jielai Xia Qingchuan Zhao Daiming Fan Kaichun Wu Yongzhan Nie | 2021 | Cancer Biology & Medicine2021，18，1： | 2 |
| 5 | Fabrication of nickel oxide functionalized zeolite USY composite as a promising adsorbent for CO_(2) capture显示文摘Adsorption process is considered to be the most promising alternative for the CO_(2) capture to the traditional energy-intensive amine absorption process,and the development of feasible and efficient CO_(2) adsorbents is still a challenge.In this work,the NiO@USY(ultrastable Y)composites with different NiO loadings were prepared for the CO_(2) adsorption using Ni(NO_(3))_(2) as the precursor.The composites were characterized by X-ray photoelectron spectroscopy,X-ray diffraction,nitrogen adsorption–desorption test,scanning electron microscopy analysis,and thermogravimetric analysis,and were evaluated for the CO_(2) adsorption capacity,CO_(2)/N2 adsorption selectivity and CO_(2) cycle adsorption capacity.The characterization results show that after the activation at 423 K,the Ni(NO_(3))_(2) species were well dispersed into the surface of zeolite USY,and after the further activation at 823 K,Ni(NO_(3))_(2) could be converted into highly dispersed NiO.The adsorption results show that the presence of the active component NiO plays an important role in improving the CO_(2) adsorption performance,and the NiO@USY composite with a NiO loading of 1.5 mmol·g^(-1) USY support displays a high adsorption capacity and adsorption selectivity for CO_(2),and shows a good cycle stability.In addition,the Clausius–Clapeyron equation was used to evaluate the isosteric heat of adsorption of CO_(2) on the NiO(1.5)@USY composite,and the heat of adsorption was 17.39–38.34 kJ·mol^(-1). | Jipeng Dong Fei Wang Guanghui Chen Shougui Wang Cailin Ji Fei Gao | 2022 | Chinese Journal of Chemical Engineering2022，35，6： | 1 |
| 6 | Machining character- istics of Nickel-based alloy with positive polarity blasting erosion arc machining 显示文摘 | Xu Hui Gu Lin Chen Jipeng | 2015 | The International Journal of Advanced Manufacturing Technology2015，，： | 1 |
| 7 | Expression of serum miR-221 in human hepatocellular carcinoma and its prognostic significance显示文摘 | Jipeng Li Yiping Wang Wanjun Yu Jun Chen Jianping Luo | 2011 | Biochemical and Biophysical Research Communications2011，，1： | 1 |
| 8 | Machining characteristics of nickel-based alloy with positive polarity blasting erosion arc machining 显示文摘 | Xu Hui Gu Lin Chen Jipeng | 2015 | The International Journal of Advanced Manufacturing Technology2015，79，5： | 1 |
| 9 | Machining charac- teristics of nickel-based alloy with positive polarity blast- ing erosion arc machining显示文摘 | XU Hui GU Lin CHEN Jipeng | 2015 | International Journal of Ad- vanced Manufacturing Technology2015，79，58： | 1 |
| 10 | Expression of serum miR-221 in human hepatocellular carcinoma and its prognostic significance显示文摘 | Jipeng Li Yiping Wang Wanjun Yu Jun Chen Jianping Luo | 2011 | Biochemical and Biophysical Research Communications2011，，1： | 1 |
| 11 | Yolk-shell nanoarchitecture for stabilizing a Ce_(2)S_(3)anode显示文摘Rare-earth sulfides are of research interest for lithium-ion batteries(LIBs)due to their abundant lithium intercalation sites and low redox voltage.However,their electrochemical performances are not satisfactory because of poor conductivity and volume change upon electrochemical cycling.Herein,nanoarchitectures ofγ-Ce_(2)S_(3)encapsulated in a hollow mesoporous carbon nanosphere(Ce_(2)S_(3)@HMCS)are fabricated using the self-template strategy combined with the in-sphere sulfuration method and tested as an LIB anode.The void space between the Ce_(2)S_(3)core and the outer layer of the carbon nanosphere has been properly designed and modulated to achieve excellent electrochemical performance in terms of electronic conductivity,reversibility,and rate capability.The reversible capacity of Ce_(2)S_(3)@HMCS is 2.6 times that of the pure Ce_(2)S_(3)anode,which can gradually increase and maintain a capacity of 282 mAh·g^(−1)at a current density of 1 A·g^(-1),and a high Coulombic efficiency(~100%)can be achieved even after 1000 cycles.This good performance is attributed to the unique yolk-shell nanostructure with a highly crystallized and stable Ce3S2 core and volume expansion buffer space upon lithiation/delithiation.Ex situ X-ray diffraction and nuclear magnetic resonance results indicate that the lithiation of Ce_(2)S_(3)@HMCS is an intercalation process.This study represents an important advancement in precise structural design with in-sphere sulfuration and sheds light on a potential direction for highperformance lithium storage. | Kanglong Hui Jipeng Fu Jie Liu Yongjin Chen Xiang Gao Tian Gao Qi Wei Chengyu Li Hongjie Zhang Mingxue Tang | 2021 | Carbon Energy2021，3，5： | 0 |
| 12 | Nanotechnology:A New Strategy for Lung Cancer Treatment Targeting Pro-Tumor Neutrophils显示文摘Primary and metastatic lung cancers are malignant lung tumors each with of which has a different pathogenesis,although both threaten patient lives.Tumor development and progression involve communication between tumor cells and the host microenvironment.Neutrophils are the most abundant immune cells in the tumor microenvironment(TME);they participate in the generation of an inflammatory milieu and influence patient survival through their anti-and pro-tumor abilities.Neutrophils can be classified into various categories according to different criteria;frequent categories include N1 antitumor neutrophils and N2 immunosuppressive neutrophils.The antitumor effects of neutrophils are reported to be mediated through a combination of reactive oxygen species,tumor necrosis factor-related apoptosis-inducing ligand,and receptor for advanced glycation end-products–cathepsin G association,as well as the regulation of the activities of other immune cells.There have also been reports that neutrophils can function as tumor promoters that contribute to lung cancer progression and metastasis by influencing processes including carcinogenesis,angiogenesis,cancer cell proliferation,and invasion ability,as well as having similar roles in the lung metastasis of other cancers.The rapid development of nanotechnology has provided new strategies for cancer treatment targeting neutrophils. | Jian Zhang Shasha Jiang Shilin Li Jipeng Jiang Jie Mei Yandong Chen Yongfu Ma Yang Liu Ying Liu | 2023 | Engineering2023，，8： | 0 |
| 13 | An ESIPT-based NIR-fluorescent probe for exosome labeling and in situ imaging显示文摘Exosomes play significant roles in physiological and tumorigenic processes and it is desirable to visualize and track the exosomes.Herein,a novel amphiphilic fluorescent probe HBT-Exo based on excited-state intramolecular proton transfer(ESIPT)mechanism is reported for exosome-labeling.Its ESIPT characteristics were confirmed by both theory calculation and experimental observation,which enable the probe to show a large Stokes shift as well as near-infrared(NIR)keto-form emission.HBT-Exo displayed excellent biocompatibility and remarkable efficiency for exosome-labeling in gastric cancer cells.Furthermore,the labeled exosomes were successfully applied for the real-time in situ imaging in mouse models. | Jipeng Ding Runsha Xiao Anyao Bi Guanyang Chen Nengwei Zhang Zihua Chen Xueping Feng Wenbin Zeng | 2023 | Chinese Chemical Letters2023，34，11： | 0 |
| 14 | Hybrid coating SnO_(2)for enhanced Li ions storage显示文摘Anode SnO_(2)in lithium-ion batteries suffers from volume expansion and agglomeration.Here,the SnO_(2)nanoparticles are hybrided with ZrO_(2)particles by the support of carbon nanotube networks.The obtained SnO_(2)/C/ZrO_(2)composite shows improved electrochemical performances.Investigations reveal that the carbon nanotubes shorten the transmission path of electrons and Li^(+) ions.Ball milling with ZrO_(2)promotes the formation of nanosized SnO_(2)to weaken the internal strain change,being beneficial to buffering volume change during electrochemical cycling afterwards.High-resolution 6.7Li NMR investigations indicate that conversion and alloying reactions are stepwise involved for SnO_(2)/C/ZrO_(2)anode.The strategy of designing SnO_(2)/C/ZrO_(2)composite from the morphology-controlled metal-organic frameworks for energy storage widens the possibility to fabricate promising materials with enhanced performances. | Yanan Gao Jie Liu Chenjie Lou Hailiang Geng Jipeng Fu Chengyu Li Yongjin Chen Cong Wang Wenda Zhang Xiaojun Kuang Yifan Liu Xiang Gao Mingxue Tang | 2023 | Chinese Chemical Letters2023，34，12： | 0 |
| 15 | Comprehensive reutilization of herbal waste:Coproduction of magnolol,honokiol,and β-amyrin from Magnolia officinalis residue显示文摘Herbal extraction residues(HERs)cause serious environmental pollution and resource waste.In this study,a novel green route was designed for the comprehensive reutilization of all components in HERs,taking Magnolia officinalis residues(MOR)as an example.The reluctant structure of MOR was first destroyed by alkali pretreatment to release the functional ingredients(magnolol and honokiol)originally remaining in MOR and to make MOR more accessible for hydrolysis.A metal–organic frame material MIL-101(Cr)with a maximum absorption capacity of 255.64 mg g^(-1)was synthesized to absorb the released honokiol and magnolol from the pretreated MOR solutions,and 40 g L^(-1)reducing sugars were obtained with 81.8%enzymatic hydrolysis rate at 10%MOR solid loading.Finally,382 mg L-1β-amyrin was produced from MOR hydrolysates by an engineered yeast strain.In total,1 kg honokiol,8 kg magnolol,and 7.64 kg β-amyrin could produce from 1 ton MOR by this cleaner process with a total economic output of 170,700 RMB. | Lukun Xiao Anyi Zhao Jie Qiu An Liu Sha Chen Jinzhu Jiang Jun Zhang Cong Guo Jipeng Di Jintang Cheng Chang Chen Kangxin Hou Aiping Zhang Yan Liu Caixia Wang | 2024 | Green Energy & Environment2024，9，2： | 0 |
| 16 | Simulation of temperature distribution and discharge crater of SiC_(p)/Al composites in a single-pulsed arc discharge显示文摘SiC_(p)/Al composites are difficult-to-cut materials.In recent years,electrical arc discharge machining has been developed to improve the machinability of these materials.However,there is a big challenge to build a satisfactory heat transfer model of SiC_(p)/Al composites in the arc machining.This is not only because of the material property difference between the reinforcement and matrix material but also because of the micro-dimension Si C reinforcements.This paper established a new heat conduction simulation model considering the Si C particle-Al matrix interface and the phase change effects in a single-pulsed arc discharge of SiC_(p)/Al composites.A novel Si C particle-Al matrix cell geometric model was designed firstly.Then,the temperature distribution at a different depth from the workpiece surface was analyzed,the influence of sic volume fraction on temperature field was studied,and the contribution of the interface thermal resistance and latent heat were explained.To demonstrate the validity of the new numerical model,comparisons and verifications were employed.Finally,the method of improving the model was proposed and the machining mechanism of arc discharge of SiC_(p)/Al matrix materials was discussed.It was found that high temperature is prone to concentrate on the surface layers of the workpiece especially when the Si C fraction is high,also,the temperature fluctuates respectively at the evaporation point of aluminum and Si C,and the Si C-Al resistance has less influence on temperature distribution compared to latent heat,etc.The model build in this work improves the simulation accuracy observably compared to the previous model,and the simulation work will help to acquire a detailed mechanism of material removal of SiC_(p)/Al composites in the arc discharge machining. | Jipeng CHEN Lin GU Wansheng ZHAO Mario GUAGLIANO | 2021 | Chinese Journal of Aeronautics2021，34，9： | 0 |
| 17 | A novel method of utilizing static mixer to obtain mixing homogeneity of multi-species powders in laser metal deposition显示文摘Real-time mixing of multi-species powder challenges Laser Metal Deposition(LMD)of Functionally Graded Materials(FGMs).The current work proposes a novel method of using a static mixer to realize rapid,uniform multi-species powder mixing.Firstly,copper powder and 316L stainless steel powder are selected to complete the powder mixing observation experiment with Scanning Electron Microscope(SEM)and Energy Dispersive Spectrometer(EDS).Secondly,computational fluid dynamics and particle mixing simulation models are used to analyze the flow field and particle motion characteristics in the static mixer.Finally,LMD experiment and metallo-graphic observation are carried out with 316L stainless steel powder and WC powder to verify the feasibility of the static mixer.This study provides a theoretical and practical basis for powder mixing in laser processing with a static mixer.The conclusions can also be applied to other processing fields requiring real-time and uniform mixing of multi-species powders. | Jipeng CHEN Shouchun XIE He HUANG | 2023 | Chinese Journal of Aeronautics2023，36，1： | 0 |
| 18 | Multiple transition metals modulated hierarchical networks for high performance of metal-ion batteries显示文摘Searching anodes with excellent electrochemical performance has been in great demand for rechargeable metal ion batteries. In this contribution, Fe/Co co-doped Ni S with N-based carbon(Fe Co-NiS@NC) derived from trimetallic Prussian blue analogue is designed and synthesized. The composition can be easily adjusted and modulated by multi-metals. In addition, the well-designed carbon nanocubes effectively promote electronic conductivity and buffer the volume change upon charge and discharge cycling, resulting in good capacity and long-term cycle life for both lithium-ion batteries and sodium-ion batteries, with capacities of 1018 m Ah g^(-1)(vs. Li/Li^(+)) and 454 m Ah g^(-1)(vs. Na/Na^(+)), respectively, after 100 cycles.Kinetics studies indicate that the electrochemical behaviors are manipulated by both diffusion and pseudocapacitance processes. These strategies would open new opportunities and potention for novel energy storage. | Jie Liu Chenjie Lou Jipeng Fu Xuan Sun Jingrong Hou Jiwei Ma Yongjin Chen Xiang Gao Ligang Xu Qi Wei Mingxue Tang | 2022 | Journal of Energy Chemistry2022，31，7： | 0 |
| 19 | Disturbing cytoskeleton by engineered nanomaterials for enhanced cancer therapeutics显示文摘Cytoskeleton plays a significant role in the shape change,migration,movement,adhesion,cytokinesis,and phagocytosis of tumor cells.In clinical practice,some anti-cancer drugs achieve cytoskeletal therapeutic effects by acting on different cytoskeletal protein components.However,in the absence of cell-specific targeting,unnecessary cytoskeletal recombination in organisms would be disastrous,which would also bring about severe side effects during anticancer process.Nanomedicine have been proven to be superior to some small molecule drugs in cancer treatment due to better stability and targeting,and lower side effects.Therefore,this review summarized the recent developments of various nanomaterials disturbing cytoskeleton for enhanced cancer therapeutics,including carbon,noble metals,metal oxides,black phosphorus,calcium,silicon,polymers,peptides,and metal-organic frameworks,etc.A comprehensive analysis of the characteristics of cytoskeleton therapy as well as the future prospects and challenges towards clinical application were also discussed.We aim to drive on this emerging topic through refreshing perspectives based on our own work and what we have also learnt from others.This review will help researchers quickly understand relevant cytoskeletal therapeutic information to further advance the development of cancer nanomedicine. | Xueli Xu Shanbin Xu Jipeng Wan Diqing Wang Xinlong Pang Yuan Gao Nengyi Ni Dawei Chen Xiao Sun | 2023 | Bioactive Materials2023，，11： | 0 |
| 20 | Ensemble learning system to identify nutritional risk and malnutrition in cancer patients without weight loss information显示文摘Dear Editor,Malnutrition is a prevalent disease in oncology practice(Arends et al.,2017).With its cancer-specific prevalence ranging from 21%–72%,malnutrition is responsible for 10%–20% cancer deaths(Yin et al.,2021b).However,malnutrition is often underestimated,misclassified,or left untreated in cancer care(Hébuterne et al.,2014). | Liangyu Yin Jie Liu Ming Liu Jin Zheng Aiguo Xu Quanjun Lyu Yongdong Feng Zengqing Guo Hu Ma Jipeng Li Zhikang Chen Hui Wang Zengning Li Chunling Zhou Xi Gao Min Weng Qinghua Yao Wei Li Tao Li Hanping Shi Hongxia Xu | 2023 | Science China(Life Sciences)2023，66，5： | 0 |
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