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| 1 | Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury显示文摘The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan,Hubei province,and rapidly spread to many provinces in China as well as other countries.Here we report the epidemiological,clinical,laboratory,and radiological characteristics,as well as potential biomarkers for predicting disease severity in 2019-nCoV-infected patients in Shenzhen,China.All 12 cases of the 2019-nCoV-infected patients developed pneumonia and half of them developed acute respiratory distress syndrome (ARDS).The most common laboratory abnormalities were hypoalbuminemia,lymphopenia,decreased percentage of lymphocytes (LYM) and neutrophils (NEU),elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH),and decreased CD8 count.The viral load of 2019-nCoV detected from patient respiratory tracts was positively linked to lung disease severity.ALB,LYM,LYM (%),LDH,NEU (%),and CRP were highly correlated to the acute lung injury.Age,viral load,lung injury score,and blood biochemistry indexes,albumin (ALB),CRP,LDH,LYM (%),LYM,and NEU (%),may be predictors of disease severity.Moreover,the Angiotensin Ⅱlevel in the plasma sample from 2019-nCoV infected patients was markedly elevated and linearly associated to viral load and lung injury.Our results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection. | Yingxia Liu Yang Yang Cong Zhang Fengming Huang Fuxiang Wang Jing Yuan Zhaoqin Wang Jinxiu Li Jianming Li Cheng Feng Zheng Zhang Lifei Wang Ling Peng Li Chen Yuhao Qin Dandan Zhao Shuguang Tan Lu Yin Jun Xu Congzhao Zhou Chengyu Jiang Lei Liu | 2020 | Science China(Life Sciences)2020,63,3: | 157 |
| 2 | The Epitope Study on the SARS-CoV Nucleocapsid Protein显示文摘The nucleocapsid protein (N protein) has been found to be an antigenic protein in a number of coronaviruses. Whether the N protein in severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is antigenic remains to be elucidated. Using Western blot and Enzyme-linked Immunosorbent Assay (ELISA),the recombinant N proteins and the synthesized peptides derived from the N protein were screened in sera from SARS patients. All patient sera in this study displayed strong positive immunoreactivities against the recombinant N proteins,whereas normal sera gave negative immunoresponses to these proteins, indicating that the N protein of SARS-CoV is an antigenic protein. Furthermore, the epitope sites in the N protein were determined by competition experiments, in which the recombinant proteins or the synthesized peptides competed against the SARS-CoV proteins to bind to the antibodies raised in SARS sera. One epitope site located at the C-terminus was confirmed as the most antigenic region in this protein. A detailed screening of peptide with ELISA demonstrated that the amino sequence from Codons 371 to 407 was the epitope site at the C-terminus of the N protein. Understanding of the epitope sites could be very significant for developing an effective diagnostic approach to SARS. | Shuting Li, Liang Lin, Hao Wang, Jianning Yin, Yan Ren, Zhe Zhao, Jie Wen, Cuiqi Zhou, Xumin Zhang, Xiaolei Li, Jingqiang Wang, Zhengfeng Zhou, Jinxiu Liu, Jianmin Shao, Tingting Lei, Jianqiu Fang, Ningzhi Xu, and Siqi LiuBeijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300, China & Beijing Proteomics Institute, Beijing 101300, China | 2003 | Genomics, Proteomics & Bioinformatics2003,1,3: | 9 |
| 3 | Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury显示文摘A recent outbreak of pneumonia in Wuhan,China was found to be caused by a 2019 novel coronavirus(2019-nCoV or SARS-CoV-2 or HCoV-19).We previously reported the clinical features of 12 patients with2019-n Co V infections in Shenzhen,China.To further understand the pathogenesis of COVID-19 and find better ways to monitor and treat the disease caused by 2019-n Co V,we measured the levels of 48 cytokines in the blood plasma of those 12 COVID-19 patients.Thirty-eight out of the 48 measured cytokines in the plasma of 2019-n Co V-infected patients were significantly elevated compared to healthy individuals.Seventeen cytokines were linked to 2019-nCoV loads.Fifteen cytokines,namely M-CSF,IL-10,IFN-α2,IL-17,IL-4,IP-10,IL-7,IL-1 ra,G-CSF,IL-12,IFN-γ,IL-1α,IL-2,HGF and PDGF-BB,were strongly associated with the lung-injury Murray score and could be used to predict the disease severity of2019-n Co V infections by calculating the area under the curve of the receiver-operating characteristics.Our results suggest that 2019-nCoV infections trigger extensive changes in a wide array of cytokines,some of which could be potential biomarkers of disease severity of 2019-n Co V infections.These findings will likely improve our understanding of the immunopathologic mechanisms of this emerging disease.Our results also suggest that modulators of cytokine responses may play a therapeutic role in combating the disease once the functions of these elevated cytokines have been characterized. | Yingxia Liu Cong Zhang Fengming Huang Yang Yang Fuxiang Wang Jing Yuan Zheng Zhang Yuhao Qin Xiaoyun Li Dandan Zhao Shunwang Li Shuguang Tan Zhaoqin Wang Jinxiu Li Chenguang Shen Jianming Li Ling Peng Weibo Wu Mengli Cao Li Xing Zhixiang Xu Li Chen Congzhao Zhou William J Liu Lei Liu Chengyu Jiang | 2020 | National Science Review2020,7,6: | 6 |
| 4 | The effect of slight to minor biodegradation on C_6 to C_7 light hydrocarbons in crude oils: a case study from Dawanqi Oilfield in the Tarim Basin,NW China显示文摘Light hydrocarbons(LHs) are one of the main petroleum fractions in crude oils, and carry much information regarding the genetic origin and alteration of crude oils. But secondary alterations—especially biodegradation—have a significant effect on the composition of LHs in crude oils. Because most of the LHs affected in oils underwent only slight biodegradation(rank 1 on the biodegradation scale), the variation of LHs can be used to describe more the refined features of biodegradation. Here,23 crude oils from the Dawanqi Oilfield in the Tarim Basin, NW China, eleven of which have been biodegraded to different extents, were analyzed in order to investigate the effect of slight to minor biodegradation on C_6–C_7 LHs.The study results showed that biodegradation resulted in the prior depletion of straight-chained alkanes, followed by branched alkanes. In slight and minor biodegraded oils,such biodegradation scale could not sufficiently affect C_6–C_7cycloalkanes. For branched C_6–C_7 alkanes, generally,monomethylalkanes are biodegraded earlier than dimethylalkanes and trimethylalkanes, which indicates that branched alkanes are more resistant to biodegradation, with the increase of substituted methyl groups on parent rings.The degree of alkylation is one of the primary controlling factors on the biodegradation of C_6–C_7 LHs. There is a particular case: although 2,2,3-trimethylbutane has a relative higher alkylation degree, 2,2-dimethylpentane is more resistant to biodegradation than 2,2,3-trimethylbutane. 2,2-Dimethylpentane is the most resistant to biodegradation in branched C_6–C_7 alkanes. Furthermore, the 2-methylpentane/3-methylpentane and 2-methylhexane/3-methylhexane ratios decreased steadily with increasing biodegradation,which implies that isomers of bilateral methyl groups are more prone to bacterial attack relative to mid-chain isomers. The position of the alkyls on the carbon skeleton is also one of the critical factors controlling the rate of biodegradation. With increasing biodegradation, Mango's LH parameters K1 values decrease and K2 values increase,the values of n-heptane and isoheptane decrease, and the indices of methylcyclohexane and cyclohexane increase.LH parameters should be applied cautiously for the biodegraded oils. Because biodegraded samples belong to slight or minor biodegraded oils, the values of n-heptane and isoheptane from Dawanqi Oilfield can better reflect and determine the ‘‘Biodegraded'' zone. When the heptane value is 0–21 and the isoheptane value is 0–2.6, the crude oil in Dawanqi Oilfield is defined as the ‘‘Biodegraded'' zone. | Lu Yang Chunming Zhang Meijun Li Jing Zhao Xuening Qi Jinxiu Du | 2016 | Acta Geochimica2016,35,2: | 5 |
| 5 | Adipose-derived stem cells inhibit dermal fibroblast growth and induce apoptosis in keloids through the arachidonic acid-derived cyclooxygenase-2/prostaglandin E2 cascade by paracrine显示文摘Background:The clinical features of keloids consist of aberrant proliferation,secretion,differentiation and apoptosis of keloid dermis-derived fibroblasts(KFBs).Notably,the apoptosis rate of KFBs is lower than the proliferation rate.Though the anti-fibrotic effect of adipose-derived stem cells(ADSCs)on keloids has become a hot topic of research,the exact anti-fibrotic mechanism of the paracrine effect remains unclear.This study aimed to find out how the conditioned medium of ADSCs(ADSC-CM)exerts an anti-fibrotic effect in KFBs.Methods:KFBs and ADSCs were extracted and cultured.Then,ADSC-CM was prepared.Whether ADSC-CM could inhibit KFB growth and induce apoptosis was verified by the use of a cell counting kit-8,an 5-Ethynyl-2-deoxyuridine(Edu)kit and flow cytometry.The expressions of cyclooxygenase-1(COX-1),COX-2,caspase 3 and B-cell lymphoma-2(Bcl-2)in ADSC-CM-cultured KFBs were tested by real-time PCR and western blotting.To clarify the role of COX-2 in ADSC-CM-induced KFB apoptosis,a specific COX-2 inhibitor,celecoxib,was applied to KFBs cultured in ADSC-CM.Moreover,we tested the production of arachidonic acid(AA)and prostaglandin E2(PGE2)by ELISA.Then,we established a keloid transplantation model in a nude mouse to validate the therapeutic effect in vivo.Results:The proliferation ability of KFBs cultured in ADSC-CM was found to be weakened and apoptosis was significantly increased.Caspase 3 expression was significantly upregulated and Bcl-2 was downregulated in ADSC-CM-cultured KFBs.Furthermore,ADSC-CM strikingly elevated COX-2 mRNA and protein expressions,but COX-1 expression was unaltered.COX-2 inhibitors reduced ADSC-CM-induced apoptosis.Additionally,COX-2 inhibition blocked the elevation of caspase 3 and reversed the decrease in Bcl-2 expression.ADSC-CM increased PGE2 levels by 1.5-fold and this effect was restrained by COX-2 inhibition.In the nude mouse model,expressions of AA,COX-2 and PGE2 were higher in the translated keloid tissues after ADSC-CM injection than in the controls.Conclusions:We showed activation of the COX-2/PGE2 cascade in KFBs in response to ADSC-CM.By employing a specific COX-2 inhibitor,COX-2/PGE2 cascade activation played a crucial role in mediating the ADSC-CM-induced KFB apoptosis and anti-proliferation effects. | Jinxiu Yang Shiyi Li Leren He Minliang Chen | 2021 | Burns & Trauma2021,9,1: | 4 |
| 6 | The norepinephrine transporter gene is associated with the retardation symptoms of major depressive disorder in the Han Chinese population显示文摘The norepinephrine transporter plays an important role in the pathophysiology and pharmacological treatment of major depressive disorder.Consequently,the norepinephrine transporter gene is an attractive candidate in major depressive disorder research.In the present study,we evaluated the depression symptoms of subjects with major depressive disorder,who were all from the North of China and of Han Chinese origin,using the Hamilton Depression Scale.We examined the rela-tionship between two single nucleotide polymorphisms in the norepinephrine transporter,rs2242446 and rs5569,and the retardation symptoms of major depressive disorder using quantitative trait testing with the UNPHASED program.rs5569 was associated with depressed mood,and the GG genotype may be a risk factor for this;rs2242446 was associated with work and interest,and the TT genotype may be a risk factor for loss of interest.Our findings suggest that rs2242446 and rs5569 in the norepinephrine transporter gene are associated with the retardation symptoms of depression in the Han Chinese population. | Xinrong Li Ning Sun Yong Xu Yanfang Wang Suping Li Qiaorong Du Juyi Peng Jinxiu Luo Kerang Zhang | 2012 | Neural Regeneration Research2012,7,25: | 3 |
| 7 | Identifying human body states by using a flexible integrated sensor显示文摘Flexible sensors are required to be lightweight,compatible with the skin,sufficiently sensitive,and easily integrated to extract various kinds of body vital signs during continuous healthcare monitoring in daily life.For this,a simple and low-cost flexible temperature and force sensor that uses only two carbon fiber beams as the sensing layer is reported in this work.This simple,flexible sensor can not only monitor skin temperature changes in real time but can also extract most pulse waves,including venous waves,from most parts of the human body.A pulse diagnostic glove containing three such flexible sensors was designed to simulate pulse diagnostic methods used in traditional Chinese medicine.Wearable equipment was also designed in which four flexible sensors were fixed onto different body parts(neck,chest,armpit,and fingertip)to simultaneously monitor body temperature,carotid pulse,fingertip artery pulse,and respiratory rate.Four important physiological indicators—body temperature(BT),blood pressure(BP),heart rate(HR),and respiratory rate(RR)—were extracted by the wearable equipment and analyzed to identify exercise,excited,tired,angry,and frightened body states. | Ying Jin Guoning Chen Kete Lao Songhui Li Yong Lu Yufeng Gan Zhundong Li Jiajia Hu Jingcheng Huang Jinxiu Wen Honggui Deng Min Yang Zhiming Chen Xiaoyan Hu Baowen Liang Jianyi Luo | 2020 | npj Flexible Electronics2020,4,1: | 2 |
| 8 | Characteristics of Tight Reservoir in Shahezi Formation of Zhaozhou Area in Songliao Basin显示文摘Through the statistical analysis of reservoir physical property,thin slice,scanning electron microscopy and mercury injection experiment data of Shahezi formation in Zhaozhou area,there are two main directions of provenance systems.One from central uplift belt in western,and other from slope zone in eastern.Reservoirs roughly grow in sandstone which in fan-delta in | LI Chenhui YANG Jinxiu | 2015 | Acta Geologica Sinica(English Edition)2015,89,A01: | 2 |
| 9 | Effects of fasting and refeeding on expression of MAFbx and MuRF1 in chick skeletal muscle显示文摘The present study investigated the effects of fasting and refeeding on the expression of proteasome-related genes and their downstream targets in the skeletal muscles of chicks.Seven-day-old chicks were fasted for 24 or 48 h and then refed for 4 h.The expression levels of MAFbx and MuRF1,which function as E3 ligases in the ubiquitin-proteasome system,were investigated at the mRNA and protein levels.MAFbx and MuRF1 expression were increased by fasting and these increases were downregulated by refeeding.The expression of the target proteins of these E3 ligases,MyoD and M-CK,was also analyzed.The levels of these proteins were downregulated by fasting,and these decreases were rescued by refeeding.The results of this study indicate that fasting stimulates MAFbx and MuRF1 expression in chicks,possibly leading to increased degradation of their corresponding target proteins. | LI QingHe LI JinXiu LAN He WANG Nan HU XiaoXiang CHEN Li LI Ning | 2011 | Science China(Life Sciences)2011,54,10: | 1 |
| 10 | Sonochemical synthesis, characterization and photocatalytic properties of a novel cube-shaped CaSn(OH) 6显示文摘 | Sugang Meng Danzhen Li Meng Sun Wenjuan Li Jinxiu Wang Jing Chen Xianzhi Fu Guangcan Xiao | 2011 | Catalysis Communications2011,,11: | 1 |
| 11 | Effects of daily light integral on tomato(Solanum lycopersicon L.)grafting and quality in a controlled environment显示文摘As the source of energy and biological signals,light can influence the healing process of grafted seedlings by regulating the synthesis of the endogenous hormone,regeneration of wound-healing tissue,and connection of vascular tissue in grafted seedlings.The effect of daily light integral(DLI)on the healing process and seedling quality of tomato(Solanum lycopersicum L.)was analyzed in this study,with the comparison of grafted seedlings treated in dark for 7 d after grafting.The results showed that the height increment of scion and rootstock,adhesion of graft union,stem flow,total chlorophyll content,and net photosynthesis rate increased gradually with increasing light intensity,and no longer increased significantly when the DLI was higher than 5.04 mol/m^(2)·d.The contents of auxin(IAA)and gibberellin(GA)in tomato leaves increased and abscisic acid(ABA)decreased with the increase of DLI.However,there was no significant difference between the treatments with DLI higher than 6.48 mol/m^(2)·d.Both the biomass and energy use efficiency(EUE)of grafted seedlings increased with DLI in a certain range and then decreased.The biomass was the largest when DLI was 5.04 mol/m^(2)·d.However,EUE was highest when DLI was 7.46 mol/m^(2)·d.In conclusion,a suitable DLI is beneficial to cultivate high-quality grafted tomato seedlings,and increasing DLI within a certain range can promote biomass accumulation,connection of vascular tissue,and endogenous hormone biosynthesis in tomato grafted seedlings during the healing period.The lighting environment with DLI of 5.04 mol/m^(2)·d(light intensity of 100μmol/m^(2)·s and light time of 14 h/d)is recommended for the healing treatment in high-quality production,which also improves EUE during the healing period of tomato grafted seedlings. | Jinxiu Song Yulong Fan Xingqun Li Yuzhu Li Hanping Mao Zhiyu Zuo Zhirong Zou | 2022 | International Journal of Agricultural and Biological Engineering2022,15,6: | 1 |
| 12 | A promising new photocatalyst CdSnO 3 ·3H 2 O for air purification under ambient condition显示文摘 | Yibin Chen Danzhen Li Jing Chen Jinxiu Wang Sugang Meng Jiangjun Xian Xianzhi Fu Yu Shao | 2013 | Applied Catalysis B: Environmental2013,,: | 1 |
| 13 | Misperception and pro-environmental behaviors of the Chinese public toward air pollution显示文摘This study analyzes the misperceptions of the Chinese public about air pollution levels and other potential predictors of participation in pro-environmental behaviors based on the 2013 Chinese General Social Survey(CGSS).In this paper,misperception is defined as the difference between subjective perceptions of air pollution and measurements through objective monitoring.We find that pessimistic respondents are more likely to participate in pro-environmental behaviors.The media use and evaluation of the environmental performance of the local government significantly stimulate pro-environmental participation.The results reveal that knowledge and concern about the environment can mitigate the negative effect of optimistic bias on pro-environmental behaviors.In regions where environmental information is widely available,environmental pessimists are especially more likely to participate in such activities.This finding suggests that the government should provide not only accurate information about environmental pollution but also relevant education to enhance the environmental awareness of the public and stimulate pro-environmental participation. | Xiuqin Wu Ge Wu Jinxiu Ding Ding Li Chin-Hsien Yu Hongxia Xu | 2021 | Chinese Journal of Population,Resources and Environment2021,19,2: | 1 |
| 14 | To observe the application effect of high qualitynursing for coronary heart disease 显示文摘 | Li Jinxiu | 2014 | Modern health2014,20,8: | 1 |
| 15 | Cobalt-based metal-organic framework as a dual cooperative controllable release system for accelerating diabetic wound healing显示文摘Nano Research volume 13,pages2268–2279(2020)Cite this article 131 Accesses 1 Altmetric Metrics details Abstract Insufficient angiogenesis in the chronic wound of the diabetic is one of the most important causes that making the wound unable to heal itself.In this work,a cobalt-based metal–organic framework(ZIF-67)was introduced as a carrier for loading a pro-angiogenic small molecular drug(dimethyloxalylglycine,DMOG).To achieve a long-term angiogenic therapy on the diabetic wound beds,a dual cooperative controllable release system has been designed by incorporating the drug-loaded ZIF-67 nanoparticles into the micro-patterned PLLA/Gelatin nanofibrous scaffolds.The results showed that DMOG was incorporated into ZIF-67 with a high loading ratio(359.12 mg/g),and the drug-loaded ZIF-67 nanoparticles were well embedded in the circular patterned scaffold.Notably,the DMOG as well as Co ions could continuously release from the scaffold for more than 15 days.The in vitro studies showed that the released Co ions and DMOG from the micropatterned nanofibrous scaffolds could synergistically promote the proliferation,migration and tube formation of the human umbilical vein endothelial cells(HUVECs)by inducing a hypoxia response and upregulating the expression of angiogenesis-related genes such as HIF-1α,VEGF and e-NOS.Furthermore,the in vivo results demonstrated that the composite scaffolds could significantly enhance angiogenesis,collagen deposition and eliminate inflammation in the diabetes wounds.These results indicate that the cobalt-based metal–organic framework as a dual cooperative controllable release system provides a new strategy for enhancing angiogenesis and promoting diabetic wound healing. | Jiankai Li Fang Lv Jinxiu Li Yuxin Li Jingduo Gao Jian Luo Feng Xue Qinfei Ke He Xu | 2020 | Nano Research2020,13,8: | 1 |
| 16 | A Strategy for Searching Antigenic Regions in the SARS-CoV Spike Protein显示文摘In the face of the worldwide threat of severe acute respiratory syndrome (SARS)to human life, some of the most urgent challenges are to develop fast and accurate analytical methods for early diagnosis of this disease as well as to create a safe anti-viral vaccine for prevention. To these ends, we investigated the antigenicity of the spike protein (S protein), a major structural protein in the SARS-coronavirus (SARS-CoV). Based upon the theoretical analysis for hydrophobicity of the S protein, 18 peptides were synthesized. Using Enzyme-Linked Immunosorbent Assay (ELISA), these peptides were screened in the sera from SARS patients. According to these results, two fragments of the S gene were amplified by PCR and cloned into pET-32a. Both S fragments were expressed in the BL-21 strain and further purified with an affinity chromatography. These recombinant S fragments were confirmed to have positive cross-reactions with SARS sera, either by Western blot or by ELISA. Our results demonstrated that the potential epitope regions were located at Codons 469-882 in the S protein, and one epitope site was located at Codons 599-620. Identification of antigenic regions in the SARS-CoV S protein may be important for the functional studies of this virus or the development of clinical diagnosis. | Yan Ren, Zhengfeng Zhou, Jinxiu Liu, Liang Lin, Shuting Li, Hao Wang, Ji Xia, Zhe Zhao, Jie Wen, Cuiqi Zhou, Jingqiang Wang, Jianning Yin, Ningzhi Xu, and Siqi LiuBeijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300, China & Beijing Proteomics Institute, Beijing 101300, China. | 2003 | Genomics, Proteomics & Bioinformatics2003,1,3: | 1 |
| 17 | Effects of fluoride additives on dehydrogenation behaviors of2LiBH4-MgH2system显示文摘 | KOU Huaqin XIAO Xuezhang LI Jinxiu | 2012 | Int J Hydrogen Energ2012,37,1: | 1 |
| 18 | Browninginhibition on fresh-cut chestnut kernel by exogenousnitric oxide显示文摘 | Jingying Shi Jinxiu Li Shuhua Zhu | 2011 | International Journal of Food Science andTechnology2011,,46: | 1 |
| 19 | Highly efficient oxidation of gaseous benzene on novel Ag3VO4/TiO2 nanocomposite photocatalysts under visible and simulated solar light irradiation显示文摘 | Wang Jinxiu Ruan Hong Li Wenjuan | 2012 | The Journal of Physical Chemistry C2012,116,13: | 1 |
| 20 | Laboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 Infection显示文摘The worldwide epidemic of coronavirus disease 2019(COVID-19)is ongoing.Rapid and accurate detection of the causative virus SARSCoV-2 is vital for the treatment and control of COVID-19.In this study,the comparative sensitivity of different respiratory specimen types were retrospectively analyzed using 3,552 clinical samples from 410 COVID-19 patients confirmed by Guangdong CDC(Center for Disease Control and Prevention).Except for bronchoalveolar lavage fluid(BALF),the sputum possessed the highest positive rate(73.4%–87.5%),followed by nasal swabs(53.1%–85.3%)for both severe and mild cases during the first 14 days after illness onset(d.a.o.).Viral RNA could be detected in all BALF samples collected from the severe group within 14 d.a.o.and lasted up to 46 d.a.o.Moreover,although viral RNA was negative in the upper respiratory samples,it was also positive in BALF samples in most cases from the severe group during treatment.Notably,no viral RNA was detected in BALF samples from the mild group.Despite typical ground-glass opacity observed via computed tomographic scans,no viral RNA was detected in the first three or all upper respiratory tract specimens from some COVID-19 patients.In conclusion,sputum is most sensitive for routine laboratory diagnosis of COVID-19,followed by nasal swabs.Detection of viral RNA in BALF improves diagnostic accuracy in severe COVID-19 patients. | Yang Yang Minghui Yang Jing Yuan Fuxiang Wang Zhaoqin Wang Jinxiu Li Mingxia Zhang Jinli Wei Ling Peng Gary Wong Haixia Zheng Weibo Wu Chenguang Shen Mingfeng Liao Kai Feng Jianming Li Qianting Yang Juanjuan Zhao Lei Liu Yingxia Liu | 2020 | The Innovation2020,1,3: | 1 |