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| 1 | Memory materials and devices:From concept to application显示文摘Memory cells have always been an important element of information technology.With emerging technologies like big data and cloud computing,the scale and complexity of data storage has reached an unprecedented peak with a much higher requirement for memory technology.As is well known,better data storage is mostly achieved by miniaturization.However,as the size of the memory device is reduced,a series of problems,such as drain gate-induced leakage,greatly hinder the performance of memory units.To meet the increasing demands of information technology,novel and high-performance memory is urgently needed.Fortunately,emerging memory technologies are expected to improve memory performance and drive the information revolution.This review will focus on the progress of several emerging memory technologies,including two-dimensional material-based memories,resistance random access memory(RRAM),magnetic random access memory(MRAM),and phasechange random access memory(PCRAM).Advantages,mechanisms,and applications of these diverse memory technologies will be discussed in this review. | Zhenhan Zhang Zongwei Wang Tuo Shi Chong Bi Feng Rao Yimao Cai Qi Liu Huaqiang Wu Peng Zhou | 2020 | InfoMat2020，2，2： | 15 |
| 2 | Rectangle expansion A* pathfinding for grid maps显示文摘Search speed, quality of resulting paths and the cost of pre-processing are the principle evaluation metrics of a pathfinding algorithm. In this paper, a new algorithm for grid-based maps,rectangle expansion A*(REA*), is presented that improves the performance of A*significantly.REA*explores maps in units of unblocked rectangles. All unnecessary points inside the rectangles are pruned and boundaries of the rectangles(instead of individual points within those boundaries)are used as search nodes. This makes the algorithm plot fewer points and have a much shorter open list than A*. REA*returns jump and grid-optimal path points, but since the line of sight between jump points is protected by the unblocked rectangles, the resulting path of REA*is usually better than grid-optimal. The algorithm is entirely online and requires no offline pre-processing. Experimental results for typical benchmark problem sets show that REA*can speed up a highly optimized A*by an order of magnitude and more while preserving completeness and optimality. This new algorithm is competitive with other highly successful variants of A*. | Zhang An Li Chong Bi Wenhao | 2016 | Chinese Journal of Aeronautics2016，29，5： | 10 |
| 3 | miRNA deregulation in multiple myeloma显示文摘多重骨髓瘤(公里) 是医不好的血浆房间恶意并且是第二很普通的 hematological 癌症。它被建筑群描绘,周期性基因并且 epigenetic 畸形。最近的出版物连接了 miRNAs,到包括公里的癌症的基因管理者的一个新奇的班。miRNAs 是大约 20 核苷酸,单个海滨,镇压的非编码的 RNA 由 mRNA 的基因表示降级或翻译压抑。异常 miRNA 表示侧面在公里被描述了,并且他们在公里致病的功能的角色逐渐地正在被认出。这评论在公里管理在未来研究和 miRNAs 的利用上在公里和提议观点在 miRNAs 的角色上总结当前的文学。 | BI Chong Lei CHNG Wee Joo | 2011 | Chinese Medical Journal2011，，19： | 5 |
| 4 | Smoking and Its Relation to Metabolic Status among Chinese Adults: Analysis of a Nationwide Survey显示文摘Objective To update the estimated prevalence rates of smoking and examine major metabolic diseases associated with smoking status in Chinese adults. Methods Using a complex, multistage, probability sampling design, we recruited a nationally representative sample of 98,658 Chinese adults aged ≥18 years in 2010. Information on current, former, never, and passive smoking status was obtained using a standard questionnaire. All estimates were weighted to represent the overall Chinese adult population. Results The estimated proportion of current smokers was 28.3% for Chinese adults aged ≥18 years. The corresponding values of former and passive smokers were 5.1% and 21.4%, respectively. Additionally, former smokers were found to have a less favorable metabolic risk profile among all categories of smoking status in both men and women. The prevalence of metabolic diseases such as diabetes and hypertension also increased with a greater number of smoking pack-years in men. Conclusion The prevalences of current smoking and passive smoking remain high in Chinese adults. | DING Lin XU Yu WANG Li Min JIANG Yong ZHANG Mei LI Yi Chong LU Jie Li XU Min WANG Tian Ge LI Mian ZHAO Zhi Yun DAI Meng WANG Wei Qing ZHAO Wen Hua WANG Lin Hong BI Yu Fang NING Guang 无 | 2016 | Biomedical and Environmental Sciences2016，29，9： | 5 |
| 5 | Harmful Intrusion Detection Algorithm of Optical Fiber Pre-Warning System Based on Correlation of Orthogonal Polarization Signals显示文摘目前,预付测量基于的光纤维侵入的研究经常的虚惊率(CFAR ) 算法。尽管这些常规方法克服非静止的随机的信号的干扰,仍然在实际应用程序有很多虚惊。这是因为虚惊和侵入的直角的极化信号上没有特定的学习。为了推进,减少虚惊,我们用单个模式的纤维的 birefringence 分析光纤维信号的关联。这篇论文基于二个直角的极化信号的关联建议有害侵入察觉算法。区分虚惊和侵入的建议方法使用关联系数,它能减少虚惊。真实数据的实验,从实际环境镇定,证明在关联的差别是一个柔韧的特征。而且,结果证明建议算法能减少虚惊并且当它在光纤维警告前系统(OFPS ) 被使用时,保证察觉表演。 | Fukun BI Chong FENG Hongquan QU Tong ZHENG Chonglei WANG | 2017 | Photonic Sensors2017，7，3： | 4 |
| 6 | Self-enhanced targeted delivery of a cell wall– and membrane-active antibiotics,daptomycin, against staphylococcal pneumonia显示文摘Considering that some antibacterial agents can identify the outer structure of pathogens like cell wall and/or cell membrane, we explored a self-enhanced targeted delivery strategy by which a small amount of the antibiotic molecules were modified on the surface of carriers as targeting ligands of certain bacteria while more antibiotic molecules were loaded inside the carriers, and thus has the potential to improve the drug concentration at the infection site, enhance efficacy and reduce potential toxicity. In this study, a novel targeted delivery system against methicillin-resistant Staphylococcus aureus(MRSA)pneumonia was constructed with daptomycin, a lipopeptide antibiotic, which can bind to the cell wall of S.aureus via its hydrophobic tail. Daptomycin was conjugated with N-hydroxysuccinimidyl–polyethylene glycol–1,2-distearoyl-sn-glycero-3-phosphoethanolamine to synthesize a targeting compound(Dapt–PEG–DSPE) which could be anchored on the surface of liposomes, while additional daptomycin molecules were encapsulated inside the liposomes. These daptomycin-modified, daptomycin-loaded liposomes(DPD-L[D]) showed specific binding to MRSA as detected by flow cytometry and good targeting capabilities in vivo to MRSA-infected lungs in a pneumonia model. DPD-L[D] exhibited more favorable antibacterial efficacy against MRSA than conventional PEGylated liposomal daptomycin both in vitro and in vivo. Our study demonstrates that daptomycin-modified liposomes can enhance MRSAtargeted delivery of encapsulated antibiotic, suggesting a novel drug delivery approach for existing antimicrobial agents. | Hong Jiang Meimei Xiong Qiuyan Bi Ying Wang Chong Li | 2016 | Acta Pharmaceutica Sinica B2016，6，4： | 3 |
| 7 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
| 8 | LFM signal detection using LPP-Hough transform 显示文摘 | Guoan Bi Xiumei Li Chong Meng Samson See | 2011 | IEEE Signal Processing2011，91，： | 1 |
| 9 | Photonic amorphous topological insulator显示文摘The current understanding of topological insulators and their classical wave analogs,such as photonic topological insulators,is mainly based on topological band theory.However,standard band theory does not apply to amorphous phases of matter,which are formed by non-crystalline lattices with no long-range positional order but only shortrange order,exhibiting unique phenomena such as the glass-to-liquid transition.Here,we experimentally investigate amorphous variants of a Chern number-based photonic topological insulator.By tuning the disorder strength in the lattice,we demonstrate that photonic topological edge states can persist into the amorphous regime prior to the glass-to-liquid transition.After the transition to a liquid-like lattice configuration,the signatures of topological edge states disappear.This interplay between topology and short-range order in amorphous lattices paves the way for new classes of non-crystalline topological photonic bandgap materials. | Peiheng Zhou Gui-Geng Liu Xin Ren Yihao Yang Haoran Xue Lei Bi Longjiang Deng Yidong Chong Baile Zhang | 2020 | Light(Science & Applications)2020，9，1： | 1 |
| 10 | Microsatellite variation in Avena sterilis oat germplasm 显示文摘 | Yong- Bi F James Chong Tom Fetch | 2007 | Theor Appl Genet2007，114，： | 1 |
| 11 | FPF1 transgene leads to altered flowering time and root development in rice显示文摘 | Ming-Li Xu Jia-Fu Jiang Lei Ge Yun-Yuan Xu Hui Chen Yuan Zhao Yu-Rong Bi Jiang-Qi Wen Kang Chong | 2005 | Plant Cell Reports2005，，2： | 1 |
| 12 | Microsatellite variation in Avena sterilis oat germplasm显示文摘 | Yong Bi Fu James Chong Tom Fetch | 2007 | Theoretical and Applied Genetics2007，114，： | 1 |
| 13 | Structural survey of metal-covalent organic frameworks and covalent metal-organic frameworks显示文摘This review offers an overview of the latest developments in metal-covalent organic framework(MCOF)and covalent metal-organic framework(CMOF)materials,whose construction entails a combination of reversible coordination and covalent bonding adapted from metal-organic frameworks(MOFs)and covalent organic frameworks(COFs),respectively.With an emphasis on the MCOF and CMOF structures,this review surveys their building blocks and topologies.Specifically,the frameworks are classified based on the dimensions of their components(building blocks),namely,discrete building blocks and one-dimensional infinite building blocks.For the first category,the materials are further divided into collections of two-and three-dimensional networks based on their topologies.For the second category,the recently emerging MCOFs with woven structures are covered.Finally,the state-of-the-art in MCOF and CMOF chemistry has been laid out for promising avenues in future developments. | Chaozhi Xiong Zhenwu Shao Jia’nan Hong Kexin Bi Qingsong Huang Chong Liu | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，12： | 0 |
| 14 | A large-scale screening of metal-organic frameworks for iodine capture combining molecular simulation and machine learning显示文摘We performed large-scale molecular simulation to screen and identify metal-organic framework materials for gaseous iodine capture,as part of our ongoing effort in addressing management and handling issues of various radionuclides in the grand scheme of spent nuclear fuel reprocessing.Starting from the computation-ready experimental(CoRE)metal-organic frameworks(MOFs)database,grand canonical Monte Carlo simulation was employed to predict the iodine uptake values of the MOFs.A ranking list of MOFs based on their iodine uptake capabilities was generated,with the Top 10 candidates identified and their respective adsorption sites visualized.Subsequently,machine learning was used to establish structure-property relationships to correlate MOFs’various structural and chemical features with their corresponding performances in iodine capture,yielding interpretable common features and design rules for viable MOF adsorbents.The research strategy and framework of the present study could aid the development of high-performing MOF adsorbents for capture and recovery of radioactive iodine,and moreover,other volatile environmentally hazardous species. | Min Cheng Zhiyuan Zhang Shihui Wang Kexin Bi Kong-qiu Hu Zhongde Dai Yiyang Dai Chong Liu Li Zhou Xu Ji Wei-qun Shi | 2023 | Frontiers of Environmental Science & Engineering2023，17，12： | 0 |
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