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| 1 | 中西医医学生在叙事医学上的不同视野显示文摘医学作为一种实践科学还是治疗艺术,在现在的医学界有广泛的争论。很多人认为,医学必须要求医生在自身建立叙事情感并且更深入地挖掘病人的内心。文中的调查研究活动以台湾某教学医院的学生为研究对象,开展叙事医学项目的系列活动,采用问卷调查和量表研究,并评估和比较了中西医学生对于叙事医学作为一种学习共情和医学专业精神的方法的不同认知。 | 张千会 周碧雯 Chien - Da Huang Kuo - Chen Liao Fu - Tsai Chuang | 2017 | 中国医学伦理学2017，30，10： | 14 |
| 2 | Assessment of Waterlogging Risk in Lixiahe Region of Jiangsu Province Based on AVHRR and MODIS Image显示文摘Four images of 1991 AVHRR, 2003 and 2007 MODIS were used to extract waterlogging inundated water of three years, and three inundated water maps were overlaid to estimate waterlogging affected frequency. Based on wa-terlogging affected frequency, waterlogging hazard of pixel scale was assessed. According to the weighed score of area percentage of different waterlogging affected frequency in 13 counties/cities of Lixiahe region, waterlogging hazard rank of every county/city was assessed. Waterlogging affected frequency map and 1km×1km grid landuse map were used to assess waterlogging risk of pixel scale; and then waterlogging risk rank of every county/city was assessed by the similar method by which waterlogging hazard rank of every county/city was assessed. High risk region is located mainly in core zone of Lixiahe hinterland, medium risk region is adjacent to high risk region, and low risk region is located in the most outlying area of risk zone and mainly in south to middle part of Lixiahe region. Xinghua and Gaoyou belong to high risk city, Jiangyan belongs to medium risk city, and the other counties/cities have low or lower waterlogging risk. The method of assessing waterlogging risk in this paper is simple and applicable. This paper can provide guidance for the waterlogging risk analysis in broader area of Huaihe River Basin. | HUANG Dapeng LIU Chuang FANG Huajun PENG Shunfeng | 2008 | Chinese Geographical Science2008，18，2： | 11 |
| 3 | Effect of Arctium lappa L.in the dextran sulfate sodium colitis mouse model显示文摘AIM:To analyze the possible protective role of Arctium lappa L.(AL)in a murine model of ulcerative colitis(UC).METHODS:BALB/c mice were administered 100 mg/kg AL powder orally each day.After 7 d,colitis was induced by administration of dextran sulfate sodium(DSS)(5% W/V)in drinking water for a further 8 consecutive days.Diarrhea and bloody stools as well as colonic histology were observed.The level of interleukin-6(IL-6)and tu-mor necrosis factor-α(TNF-α)in colonic sections were detected by immunohistochemistry.RESULTS:There were significant differences in mean body weight values and disease activity indices between controls and AL-treated animals.Moreover,the histological findings showed that AL treatment can prevent mucosal edema,submucosal erosions,ulceration,inflammatory cell infiltration and colon damage.In addition,immunohistochemistry analysis showed that the levels of the inflammatory cytokines,IL-6 and TNF-α were also decreased in AL-treated groups.CONCLUSION:We suggest that AL can prevent intestinal damage and decrease inflammatory cytokines in mice with DSS-induced colitis.Thus,AL could prove to be a useful food for UC. | Tzou-Chi Huang Shinn-Shyong Tsai Li-Fang Liu Yu Lin Liu Hung-Jen Liu Kuo Pin Chuang | 2010 | World Journal of Gastroenterology2010，16，33： | 10 |
| 4 | 急性运动对ADHD患儿Go/NoGo任务测试反应准备的影响:一项ERP研究(英文)显示文摘目的:本研究旨在探测在Go/No Go任务测试中急性运动对注意力缺失过动症(attention deficit hyperactivity disorder,ADHD)患儿反应时间和反应准备的影响。方法:让19名ADHD患儿(8-12岁)在不同日期进行30 min跑台运动或观看电视节目,并对活动开展顺序加以平衡。活动后进行Go/No Go任务测试。结果:与看电视相比,运动后反应时间更短、关联性负变2(contingent negative variation,CNV2)振幅更小。ERP技术分析显示,仅在看电视阶段发现对No Go刺激的CNV1和CNV2振幅比对Go刺激大。结论:急性运动可能通过开展适当的反应准备有益于ADHD患儿,特别是在开展任务之前保持稳定的行动准备状况。 | Lan-Ya Chuang Yu-Jung Tsai Yu-Kai Chang Chung-Ju Huang Tsung-Min Hung | 2015 | Journal of Sport and Health Science2015，4，1： | 10 |
| 5 | Comparison of OA-2000 and IOL Master 500 using in cataract patients with high myopia显示文摘This study was designed to compare optical biometry measurements and predicted refraction in cataract patients with high myopia [axial length(AL) ≥26 mm] using OA-2000 and IOL Master 500. Ocular biometry measurements were performed using both biometers before surgery. Uneventful cataract surgery was performed in all patients. Postoperative manifest refraction was obtained 3 wk after surgery or later. A total of 67 eyes were examined. The AL, keratometry(K), and anterior chamber depth(ACD) of the two biometers showed excellent agreement. Predicted errors were similar and a strong positive correlation was observed(r=0.909). Out of 21 eyes(31.34%) with unsuccessful AL readings using the IOL Master 500, 20 eyes of them could be measured using OA-2000. Therefore, the biometric parameters measured by the two biometers showed good agreement. However, OA-2000 had a lower AL measurement failure rate. | Ya-Li Du Geng Wang Hui-Chun Huang Li-Yu Lin Chuang Jin Li-Fang Liu Xiu-Ru Liu Ming-Zhi Zhang | 2019 | International Journal of Ophthalmology(English edition)2019，12，5： | 10 |
| 6 | Huge pelvi-abdominal malignant inflammatory myofibroblastic tumor with rapid recurrence in a 14-year-old boy显示文摘Inflammatory myofibroblastic tumor(IMT) is an uncommon benign neoplasm with locally aggressive behavior but malignant change is rare.We report an unusual case of pelvic-abdominal inflammatory myofibroblastic tumor with malignant transformation in a 14-year-old boy presenting with abdominal pain and 9 kg body weight loss in one month.Computed tomography revealed a huge pelvi-abdominal mass(30 cm),possibly originating from the pelvic extraperitoneal space,protruding into the abdomen leading to upward displacement of the bowel loops,downward displacement of the urinary bladder,massive central necrosis,a well-enhanced peripheral solid component with prominent peritumoral vascularity.Subsequent examination confirmed the computed tomographic findings.Histopathologic examination revealed proliferative epitheloid and spindle cells,inflammatory cell infiltration and high mitotic counts.Immunohistochemistry was strongly positive for anaplastic lymphoma kinase and revealed a high proliferative index(ki-67 = 40%).DNA sequencing and electronic microscopy further confirmed the primitive fibroblastic cell phenotype of the tumor and a final diagnosis of inflammatory myofibroblastic tumor with malignant transformation was established.Rapid tumor recurrence was noted 20 d after radical tumor resection.To our knowledge,this is the largest documented case of IMT in a pediatric patient and the first report of IMT with malignant transformation originating from the pelvic extraperitoneal space. | Chia-Hsun Lu Hsuan-Ying Huang Han-Koo Chen Jiin-Haur Chuang Shu-Hang Ng Sheung-Fat Ko | 2010 | World Journal of Gastroenterology2010，16，21： | 9 |
| 7 | Lotus Leaf‑Derived Gradient Hierarchical Porous C/MoS2 Morphology Genetic Composites with Wideband and Tunable Electromagnetic Absorption Performance显示文摘Inspired by the nature,lotus leaf-derived gradient hierarchical porous C/MoS2 morphology genetic composites(GHPCM)were successfully fabricated through an in situ strategy.The biological microstructure of lotus leaf was well preserved after treatment.Different pores with gradient pore sizes ranging from 300 to 5μm were hierarchically distributed in the composites.In addition,the surface states of lotus leaf resulted in the Janus-like morphologies of MoS2.The GHPCM exhibit excellent electromagnetic wave absorption performance,with the minimum reflection loss of−50.1 dB at a thickness of 2.4 mm and the maximum effective bandwidth of 6.0 GHz at a thickness of 2.2 mm.The outstanding performance could be attributed to the synergy of conductive loss,polarization loss,and impedance matching.In particularly,we provided a brand-new dielectric sum-quotient model to analyze the electromagnetic performance of the non-magnetic material system.It suggests that the specific sum and quotient of permittivity are the key to keep reflection loss below−10 dB within a certain frequency range.Furthermore,based on the concept of material genetic engineering,the dielectric constant could be taken into account to seek for suitable materials with designable electromagnetic absorption performance. | Fei Pan Zhicheng Liu Baiwen Deng Yanyan Dong Xiaojie Zhu Chuang Huang Wei Lu | 2021 | Nano-Micro Letters2021，13，3： | 9 |
| 8 | Regularized least-squares migration of simultaneous-source seismic data with adaptive singular spectrum analysis显示文摘Simultaneous-source acquisition has been recognized as an economic and efficient acquisition method, but the direct imaging of the simultaneous-source data produces migration artifacts because of the interference of adjacent sources. To overcome this problem, we propose the regularized least-squares reverse time migration method(RLSRTM)using the singular spectrum analysis technique that imposes sparseness constraints on the inverted model. Additionally,the difference spectrum theory of singular values is presented so that RLSRTM can be implemented adaptively to eliminate the migration artifacts. With numerical tests on a flat layer model and a Marmousi model, we validate the superior imaging quality, efficiency and convergence of RLSRTM compared with LSRTM when dealing with simultaneoussource data, incomplete data and noisy data. | Chuang Li Jian-Ping Huang Zhen-Chun Li Rong-Rong Wang | 2017 | Petroleum Science2017，14，1： | 9 |
| 9 | Successful Production of an All-Female Common Carp (Cyprinus carpio L.) Population Using cyp17a1-Deficient Neomale Carp显示文摘Due to sexual dimorphism in the growth of certain cultured fish species,the production of monosex fishes is desirable for the aquaculture industry.Nowadays,the most widely practiced technique available for the mass production of monosex fish populations is sex steroid-induced sex reversal.Here,a novel strategy for the successful production of all-female(AF)common carp(Cyprinus carpio L.),to take advantage of the sexual dimorphism in growth documented in this species,has been developed using genetic engineering via single gene-targeting manipulation without any exogenous hormone treatments.Male and female heterozygous cyp17a1-deficient common carp were first obtained using the clustered regularly interspaced short palindromic repeats/CRISPR-associated endonuclease 9(CRISPR/Cas9)technique.An all-male phenotype for homozygous cyp17a1-deficient carp,regardless of the individuals’sexdetermination genotypes(XY or XX),has been observed.A male-specific DNA marker newly identified in our laboratory was used to screen the neomale carp population with the XX genotype from the cyp17a1-deficient carp.These neomale carp develop a normal testis structure with normal spermatogenesis and sperm capacity.The neomale common carp were then mated with wild-type(WT)females(cyp17a1^(+/+)XX genotype)using artificial fertilization.All the AF offspring sample fish from the neomale-WT female mating were confirmed as having the cyp17a^(1+/-)XX genotype,and normal development of gonads to ovaries was observed in 100.00%of this group at eight months post-fertilization(mpf).A total of 1000 carp fingerlings,500 from the WT male and female and 500 from the neomale and WT female mating,were mixed and reared in the same pond.The average body weight of cyp17a1^(+/-)XX females was higher by 6.60%(8 mpf)and 32.66%(12 mpf)than that of the control common carp.Our study demonstrates the first successful production of a monosex teleost population with the advantages of sexual dimorphism in growth using genetic manipulation targeting a single locus. | Gang Zhai Tingting Shu Kuangxin Chen Qiyong Lou Jingyi Jia Jianfei Huang Chuang Shi Xia Jin Jiangyan He Donghuo Jiang Xueqiao Qian Wei Hu Zhan Yin | 2022 | Engineering2022，8，1： | 7 |
| 10 | Retransmission or redundancy:Transmission reliability study in wireless sensor networks显示文摘As an application-driven network,wireless sensor network generally requires data reliability to maintain detection and response capabilities.Although two approaches,namely,retransmission and redundancy,have been proposed to enhance data reliability,the theoretical work is required to evaluate their impact on transmission reliability and energy efficiency.In this paper,we offer a comprehensive theoretical study on packet arrival probability and average energy consumption for both approaches.Our analysis and simulations indicate that when loss probabilities remain low or moderate,erasure coding,a typical redundancy-based scheme,is more energy efficient than retransmission.We also demonstrate that the resistance capability of erasure coding against packet loss weakens as the hop number increases,which motivates us to propose two improved mechanism based on the idea of the loss detection and the loss recovery.Finally,the simulation results carried out using TOSSIM verify the performance of different mechanisms both in the chain topology and the tree topology. | WEN Hao LIN Chuang REN FengYuan ZHOU Jia YUE Yao HUANG XiaoMeng | 2012 | Science China(Information Sciences)2012，55，4： | 7 |
| 11 | Plane-Wave Least-Squares Reverse Time Migration for Rugged Topography显示文摘We present a method based on least-squares reverse time migration with plane-wave encoding(P-LSRTM) for rugged topography.Instead of modifying the wave field before migration,we modify the plane-wave encoding function and fill constant velocity to the area above rugged topography in the model so that P-LSRTM can be directly performed from rugged surface in the way same to shot domain reverse time migration.In order to improve efficiency and reduce I/O(input/output) cost,the dynamic encoding strategy and hybrid encoding strategy are implemented.Numerical test on SEG rugged topography model show that P-LSRTM can suppress migration artifacts in the migration image,and compensate amplitude in the middle-deep part efficiently.Without data correction,P-LSRTM can produce a satisfying image of near-surface if we could get an accurate near-surface velocity model.Moreover,the pre-stack PLSRTM is more robust than conventional RTM in the presence of migration velocity errors. | Jianping Huang Chuang Li Rongrong Wang Qingyang Li | 2015 | Journal of Earth Science2015，26，4： | 6 |
| 12 | A Systematic Assessment of Blood Lead Level in Children and Associated Risk Factors in China显示文摘In this study, we searched multiple databases for all relevant original articles (1996-2013). To investigate blood lead levels (BLL) and possible risk factors for lead exposure among children in China A total of 388 articles met our inclusion criteria. The overall geometric mean (GM) BLL was 71 IJ.g/L, and the prevalence of elevated BLL (EBLL, defined as BLL 〉_100 Ixg/L) was l&.4&% among children. The prevalence of EBLL remained significantly higher among boys. In children less than 6 years of age, there were significantly increasing trends in both BLL and prevalence of EBLL in an age-dependent manner. The ban on leaded gasoline significantly reduced the BLL as well as EBLL prevalence; however, children whose parents had lower educational levels or were exposed to lead in the workplace had a higher EBLL prevalence. Despite its decline over time, the average BLL among children in China remains higher than the average level most recently reported in the United States. Childhood lead poisoning remains a public health problem in China. | WANG Lu LI Zhen HUANG Shao Xin DU Chuang WANG Hong HE Li Ping BI Yong Yi SHI Yong WANG Chun Hong | 2015 | Biomedical and Environmental Sciences2015，28，8： | 6 |
| 13 | Induction of jasmonic acid biosynthetic genes inhibits Arabidopsis growth in response to low boron显示文摘The essential micronutrient boron(B) has key roles in cell wall integrity and B deficiency inhibits plant growth. The role of jasmonic acid(JA) in plant growth inhibition under B deficiency remains unclear. Here,we report that low B elevates JA biosynthesis in Arabidopsis thaliana by inducing the expression of JA biosynthesis genes. Treatment with JA inhibited plant growth and, a JA biosynthesis inhibitor enhanced plant growth, indicating that the JA induced by B deficiency affects plant growth. Furthermore,examination of the JA signaling mutants jasmonate resistant1, coronatine insensitive1-2, and myc2 showed that JA signaling negatively regulates plant growth under B deficiency. We identified a low-B responsive transcription factor, ERF018, and used yeast one-hybrid assays and transient activation assays in Nicotiana benthamiana leaf cells to demonstrate that ERF018 activates the expression of JA biosynthesis genes. ERF018 overexpression(OE)lines displayed stunted growth and up-regulation of JA biosynthesis genes under normal B conditions,compared to Col-0 and the difference between ERF018 OE lines and Col-0 diminished under low B.These results suggest that ERF018 enhances JA biosynthesis and thus negatively regulates plant growth. Taken together, our results highlight the importance of JA in the effect of low B on plant growth. | Yupu Huang Sheliang Wang Chuang Wang Guangda Ding Hongmei Cai Lei Shi Fangsen Xu | 2021 | Journal of Integrative Plant Biology2021，63，5： | 5 |
| 14 | Conservative pulp treatment for Oehlers type Ⅲ dens invaginatus: A case report显示文摘BACKGROUND Diverse presentations of dens invaginatus (DI) and root canal treatment with an immature open apex often pose challenges to dentists. Adequate treatment planning for DI is the main reason for successful approach, i.e., we should consider the shape and depth of the concave folding, the condition of the original pulp, and the growth stage of the root formation. CASE SUMMARY A 9-year-old girl complained of severe pain of the right maxillary incisor (tooth 12) when chewing for two weeks. Following clinical and radiographic examinations, Oehlers type III DI of tooth 12, with an immature open apical foramen and a symptomatic periapical pathosis, was diagnosed. Cone-beam computed tomography verified the specific spatial and stereoscopic data regarding the communication between the main root canal and pseudo root canal of the involved tooth. After removing the source of infection, a mineral trioxide aggregate was selected to fill and seal the pseudo root canal;additionally, pulp capping of the main canal was performed through the interconnections between the root canals in the middle segment to preserve pulp vitality and enable continual root formation and eventual root apex closure. CONCLUSION We propose to conduct main root canal pulp capping for DI with communication between the main and pseudo root canals. | Hui-Na Lee Yuk-Kwan Chen Cheng-Hui Chen Chun-Yin Huang Ying-Hui Su Ying-Wei Huang Fu-Hsiung Chuang | 2019 | World Journal of Clinical Cases2019，7，18： | 5 |
| 15 | PCN-Fe(Ⅲ)-PTX nanoparticles for MRI guided high efficiency chemo-photodynamic therapy in pancreatic cancer through alleviating tumor hypoxia显示文摘As nanomedicine-based clinical strategies have continued to develop,the possibility of combining chemotherapy and singlet oxygen-dependent photodynamic therapy(PDT)to treat pancreatic cancer(PaC)has emerged as a viable therapeutic modality.The efficacy of such an approach,however,is likely to be constrained by the mechanisms of drug release and tumor oxygen levels.In the present study,we developed an Fe(Ⅲ)-complexed porous coordination network(PCN)which we then used to encapsulate PTX(PCN-Fe(Ⅲ)-PTX)nanoparticles(NPs)in order to treat PaC via a combination of chemotherapy and PDT.The resultant NPs were able to release drug in response to both laser irradiation and pH changes to promote drug accumulation within tumors.Furthermore,through a Fe(Ⅲ)-based Fenton-like reaction these NPs were able to convert H2O2 in the tumor site to O2,thereby regulating local hypoxic conditions and enhancing the efficacy of PDT approaches.Also these NPs were suitable for use as a T1-MRI weighted contrast agent,making them viable for monitoring therapeutic efficacy upon treatment.Our results in both cell line and animal models of PaC suggest that these NPs represent an ideal agent for mediating effective MRI-guided chemotherapy-PDT,giving them great promise for the clinical treatment of PaC. | Tao Zhang Zhenqi Jiang Libin Chen Chunshu Pan Shan Sun Chuang Liu Zihou Li Wenzhi Ren Aiguo Wu Pintong Huang | 2020 | Nano Research2020，13，1： | 4 |
| 16 | Nonlinear Optimization of Orthotropic Steel Deck System Based on Response Surface Methodology显示文摘The steel bridge deck system,directly subjected to the vehicle load,is an important component to be considered in the optimization design of the bridges.Due to its complex structure,the design parameters are coupled with each other,and many fatigue details in the system result in time-consuming calculation during structure optimization.In view of this,a nonlinear optimization method based on the response surface methodology(RSM)is proposed in this study to simplify the design process and to reduce the amount of calculations during optimization.The optimization design of the steel bridge deck system with two-layer pavement on the top of the steel deck plate is taken as an example,the influence of eight structural parameters is considered.The Box-Behnken design is used to construct a sample space in which the eight structural parameters can be distributed evenly to reduce the calculation workload.The finite element method is used to model the mechanical responses of the steel bridge deck system.From the regression analysis by the RSM,the explicit relationships between the fatigue details and the design parameters can be obtained,based on which the nonlinear optimization design of the bridge deck system is conducted.The influence of constraint functions,objective functions,and optimization algorithms is also analyzed.The method proposed in this study is capable of considering the influence of different structural parameters and different optimization objectives according to the actual needs,which will effectively simplify the optimization design of the steel bridge deck system. | Wei Huang Minshan Pei Xiaodong Liu Chuang Yan Ya Wei | 2020 | Research2020，，1： | 4 |
| 17 | Differences in pathological changes between two rat models of severe traumatic brain injury显示文摘The rat high-impact free weight drop model mimics the diffuse axonal injury caused by severe traumatic brain injury in humans,while severe controlled cortical impact can produce a severe traumatic brain injury model using precise strike parameters.In this study,we compare the pathological mechanisms and pathological changes between two rat severe brain injury models to identify the similarities and differences.The severe controlled cortical impact model was produced by an electronic controlled cortical impact device,while the severe free weight drop model was produced by dropping a 500 g free weight from a height of 1.8 m through a plastic tube.Body temperature and mortality were recorded,and neurological deficits were assessed with the modified neurological severity score.Brain edema and bloodbrain barrier damage were evaluated by assessing brain water content and Evans blue extravasation.In addition,a cytokine array kit was used to detect inflammatory cytokines.Neuronal apoptosis in the brain and brainstem was quantified by immunofluorescence staining.Both the severe controlled cortical impact and severe free weight drop models exhibited significant neurological impairments and body temperature fluctuations.More severe motor dysfunction was observed in the severe controlled cortical impact model,while more severe cognitive dysfunction was observed in the severe free weight drop model.Brain edema,inflammatory cytokine changes and cortical neuronal apoptosis were more substantial and blood-brain barrier damage was more focal in the severe controlled cortical impact group compared with the severe free weight drop group.The severe free weight drop model presented with more significant apoptosis in the brainstem and diffused blood-brain barrier damage,with higher mortality and lower repeatability compared with the severe controlled cortical impact group.Severe brainstem damage was not found in the severe controlled cortical impact model.These results indicate that the severe controlled cortical impact model is relatively more stable,more reproducible,and shows obvious cerebral pathological changes at an earlier stage.Therefore,the severe controlled cortical impact model is likely more suitable for studies on severe focal traumatic brain injury,while the severe free weight drop model may be more apt for studies on diffuse axonal injury.All experimental procedures were approved by the Ethics Committee of Animal Experiments of Tianjin Medical University,China(approval No.IRB2012-028-02)in Febru ary 2012. | Yi-Ming Song Yu Qian Wan-Qiang Su Xuan-Hui Liu Jin-Hao Huang Zhi-Tao Gong Hong-Liang Luo Chuang Gao Rong-Cai Jiang | 2019 | Neural Regeneration Research2019，14，10： | 4 |
| 18 | Differences between Marine and Terrestrial Shale Gas Accumulation:Taking Longmaxi Shale Sichuan Basin and Yanchang Shale Ordos Basin as Examples显示文摘1 Introduction With the rapid development of theory and practice,shale gas has gradually become an important part in diversified energy structure.Though a lot of research have been done mainly for shale gas exploration prospects,geological conditions and shale gas accumulation have been analyzed and summarized,prospective resources have been preliminarily predicted,and favorable exploration | PU Boling DONG Dazhong ZHAO Jingzhou ER Chuang HUANG Jinliang | 2015 | Acta Geologica Sinica(English Edition)2015，89，A01： | 3 |
| 19 | Baseline gamma-glutamyl transferase levels strongly correlate with hepatocellular carcinoma development in non-cirrhotic patients with successful hepatitis C virus eradication显示文摘 | Chung-Feng Huang Ming-Lun Yeh Pei-Chien Tsai Meng-Hsuan Hsieh Hua-Ling Yang Ming-Yen Hsieh Jeng-Fu Yang Zu-Yau Lin Shinn-Cherng Chen Liang-Yen Wang Chia-Yen Dai Jee-Fu Huang Wan-Long Chuang Ming-Lung Yu | 2014 | Journal of Hepatology2014，，： | 2 |
| 20 | T-Cell and NK/T-Cell Lymphomas in Southern Taiwan: A Study of 72 Cases in a Single Institute显示文摘 | David Lu Ching-Nan Lin Shih-Sung Chuang Wei-Shou Hwang Wen-Tsung Huang | 2004 | Leukemia & Lymphoma2004，，5： | 2 |
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