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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | Two-Dimensional Tellurium:Progress,Challenges,and Prospects显示文摘Since the successful fabrication of two-dimensional(2D)tellurium(Te)in 2017,its fascinating properties including a thickness dependence bandgap,environmental stability,piezoelectric effect,high carrier mobility,and photoresponse among others show great potential for various applications.These include photodetectors,field-effect transistors,piezoelectric devices,modulators,and energy harvesting devices.However,as a new member of the 2D material family,much less known is about 2D Te compared to other 2D materials.Motivated by this lack of knowledge,we review the recent progress of research into 2D Te nanoflakes.Firstly,we introduce the background and motivation of this review.Then,the crystal structures and synthesis methods are presented,followed by an introduction to their physical properties and applications.Finally,the challenges and further development directions are summarized.We believe that milestone investigations of 2D Te nanoflakes will emerge soon,which will bring about great industrial revelations in 2D materials-based nanodevice commercialization. | Zhe Shi Rui Cao Karim Khan Ayesha Khan Tareen Xiaosong Liu Weiyuan Liang Ye Zhang Chunyang Ma Zhinan Guo Xiaoling Luo Han Zhang | 2020 | Nano-Micro Letters2020，12，8： | 8 |
| 3 | Short-pulsed Raman fiber laser and its dynamics显示文摘We provide a perspective review over the recent development of short-pulsed Raman fiber lasers(RFLs),which can provide laser emissions with flexible wavelengths for a variety of applications as well as an excellent platform to investigate various nonlinear pulse dynamics behaviors that cannot be captured in conventional rare-earth(RE)doped counterparts.Various pulse generation techniques have been explored in RFLs.However,the output pulse performance in terms of the pulse energy,duration and stability from short-pulsed RFLs is still inferior to their RE-doped counterparts despite significant advances made over the past few decades.Therefore,more efforts are required to improve these targets.In this review,we present a detailed overview of the short-pulsed RFLs based on different mechanisms from the principle to the experiment,including the Q-switching,gainswitching,mode-locking,synchronous pumping and other innovative techniques.In addition,Raman-induced pulse dynamics in ultrafast RFLs and RE-doped mode-locked fiber lasers(MLFLs)are briefly reviewed.Finally,a perspective outlook for the future ultrafast RFLs is provided based on their potential applications in industrial and scientific research areas. | Jun Liu Jiadong Wu Hualong Chen Yu Chen Zhenhong Wang Chunyang Ma Han Zhang | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，1： | 4 |
| 4 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016，1，1： | 2 |
| 5 | Static and modal analyzing for the working table components of a machining center in ANSYS显示文摘In this paper,modal analysis theory,equivalent dynamic model of the joint surface of assembly and identification methods of joint surface parameters are the main theories.Static and modal analysis of the working table components of the FM6324 machining center is done.The three-dimensional model of the working table components is established using Pro E at first,then static characteristics is obtained through ANSYS contact analysis;finally,the dynamic model is established in ANSYS,and its dynamic characteristics is obtained through ANSYS modal analysis. | XIA Lian HU Chunyang HAN Jiang | 2012 | Computer Aided Drafting,Design and Manufacturing2012，22，2： | 2 |
| 6 | Stem cell transplantation for treating stroke:status,trends and development显示文摘The developing approaches of thrombolytic therapy, endovascular treatment, neuroprotective therapy, and stem cell therapy have enabled breakthroughs in stroke treatment. In this study, we summarize and analyze trends and progress in stem cell transplantation for stroke treatment by retrieval of literature from Thomson Reuters Web of Science database, the NIH Clinical Trial Planning Grant Program, and Clinical Trials Registration Center in North America. In the last 10 years, there has been an increasing number of published articles on stem cell transplantation for stroke treatment. In particular, research from the USA and China has focused on stem cell transplantation. A total of 2,167 articles addressing stem cell transplantation for stroke treatment from 2004 to 2013 were retrieved from the Thomson Reuters Web of Science database. The majority of these articles were from the USA(854, 39.4%), with the journal Stroke publishing the most articles(145, 6.7%). Of the published articles, 143 were funded by the National Institutes of Health(accounting for 6.6% of total publications), and 91 by the National Natural Science Foundation of China. Between 2013 and 2014, the National Institutes of Health provided financial support($130 million subsidy) for 329 research projects on stroke therapy using stem cell transplantation. In 2014, 215 new projects were approved, receiving grants of up to $70,440,000. Ninety clinical trials focusing on stem cell transplantation for stroke were registered in the Clinical Trial Registration Center in North America, with 40 trials registered in the USA(ranked first place). China had the maximum number of registered research or clinical trials(10 projects). | Wenxin Huo Xiaoyang Liu Cheng Tan Yingying Han Chunyang Kang Wei Quan Jiajun Chen | 2014 | Neural Regeneration Research2014，9，17： | 2 |
| 7 | A Novel Time-aware Frame Adjustment Strategy for RFID Anti-collision显示文摘Recently,object identification with radio frequency identification(RFID)technology is becoming increasingly popular.Identification time is a key performance metric to evaluate the RFID system.The present paper analyzes the deficiencies of the state-of-the-arts algorithms and proposes a novel sub-frame-based algorithm with adaptive frame breaking policy to lower the tag identification time for EPC global C1 Gen2 UHF RFID standard.Through the observation of slot statistics in a sub-frame,the reader estimates the tag quantity and efficiently calculates an optimal frame size to fit the unread tags.Only when the expected average identification time in the calculated frame size is less than that in the previous frame size,the reader starts the new frame.Moreover,the estimation of the proposed algorithm is implemented by the look-up tables,which allows dramatically reduction in the computational complexity.Simulation results show noticeable throughput and time efficiency improvements of the proposed solution over the existing approaches. | Haipeng Chen Kexiong Liu Chunyang Ma Yu Han Jian Su | 2018 | Computers, Materials & Continua2018，，11： | 2 |
| 8 | Polymyxin resistance caused by large-scale genomic inversion due to IS26 intramolecular translocation in Klebsiella pneumoniae显示文摘Polymyxin B and polymyxin E(colistin)are presently considered the last line of defense against human infections caused by multidrug-resistant Gram-negative organisms such as carbapenemase-producer Enterobacterales,Acinetobacter baumannii,and Klebsiella pneumoniae.Yet resistance to this last-line drugs is a major public health threat and is rapidly increasing.Polymyxin S2(S2)is a polymyxin B analogue previously synthesized in our institute with obviously high antibacterial activity and lower toxicity than polymyxin B and colistin.To predict the possible resistant mechanism of S2for wide clinical application,we experimentally induced bacterial resistant mutants and studied the preliminary resistance mechanisms.Mut-S,a resistant mutant of K.pneumoniae ATCC BAA-2146(Kpn2146)induced by S2,was analyzed by whole genome sequencing,transcriptomics,mass spectrometry and complementation experiment.Surprisingly,large-scale genomic inversion(LSGI)of approximately 1.1 Mbp in the chromosome caused by IS26mediated intramolecular transposition was found in Mut-S,which led to mgrB truncation,lipid A modification and hence S2resistance.The resistance can be complemented by plasmid carrying intact mgrB.The same mechanism was also found in polymyxin B and colistin induced drug-resistant mutants of Kpn2146(Mut-B and Mut-E,respectively).This is the first report of polymyxin resistance caused by IS26 intramolecular transposition mediated mgrB truncation in chromosome in K.pneumoniae.The findings broaden our scope of knowledge for polymyxin resistance and enriched our understanding of how bacteria can manage to survive in the presence of antibiotics. | Haibin Li Lang Sun Han Qiao Zongti Sun Penghe Wang Chunyang Xie Xinxin Hu Tongying Nie Xinyi Yang Guoqing Li Youwen Zhang Xiukun Wang Zhuorong Li Jiandong Jiang Congran Li Xuefu You | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 1 |
| 9 | Fenton Pre-Oxidation Followed by Microbial Degradation for Removing Crude Oil from Contaminated Soil显示文摘Through the Fenton pre-oxidation followed by microbial degradation,this study gave full play to its advantages while avoiding its shortcomings for the remediation of crude oil contaminated soil.The Fenton reagent coupled with different volumes of H2O2 was applied to the oil contaminated soil and then the microbial agents were introduced to biodegrade the residual oil for 15 days.The correlation between the characteristics of residual oil in soil,the changes in soil physical-chemical property after the Fenton pre-oxidation,and the biodegradation were analyzed in this paper.The results show that the above factors are strongly correlated with the subsequent biodegradation rate,and the order of correlation is as follows:the ratio of TOC to NH4+-N(R^2=0.9513)>the ratio of light oil components to the heavy oil components(R^2=0.9095)>the proportion of hydrocarbons with carbon chain number of less than C23(R^2=0.8259)>the crude oil content(R^2=0.7603)>the soil pH(R^2=0.7492)>the number of microorganisms(R^2=0.6506).During the biodegradation and pre-oxidation reactions of heavy oil components,an appropriate C:N ratio turns out to be the most critical factor in this study. | Gao Chunyang Zhang Yu Han Zhantao Song Quanwei Chen Changzhao Chen Hongkun Zheng Jin | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，3： | 1 |
| 10 | Species-specific responses to drought,salinity and their interactions in Populus euphratica and P.pruinosa seedlings显示文摘干旱和盐胁迫是严重的非生物胁迫因子,限制植物的生长和生产力,特别是在沙漠地区。本研究采用两种沙漠杨树—胡杨(Populus euphratica)和灰杨(P.pruinosa)幼苗,比较它们对干旱、盐胁迫和两者交互胁迫的耐受性。研究了在干旱、盐胁迫和交互胁迫下,胡杨和灰杨在生长、光合能力和色素含量、非结构性碳水化合物浓度、Cl−分配、渗透调节和活性氧积累等方面的物种特异性响应。研究结果表明,与胡杨相比,灰杨在干旱、盐胁迫,特别是交互胁迫下表现出更高的生长抑制作用,光合作用下降,气孔关闭和活性氧积累,抗氧化酶活性和渗透调节能力下降。此外,在盐胁迫下,胡杨限制了盐从根部向叶片的转运,并且向粗根分配的Cl−较多,向叶片分配的Cl−较少,而灰杨向叶片分配较多的Cl−。表明这两种杨树存在着物种特异性变化,在干旱、盐胁迫,特别是交互胁迫下,灰杨受到更大的负面作用。因此,在未来干旱和盐胁迫加重的气候环境下,在生态恢复和植树造林时,应考虑这两种杨树对干旱和盐胁迫的物种特异性响应和耐受性。 | Lei Yu Haojie Dong Zhijun Li Zhanjiang Han Helena Korpelainen Chunyang Li | 2020 | Journal of Plant Ecology2020，13，5： | 1 |
| 11 | Antimicrobial-coated polypropylene films with polyvinyl alcohol in packagingof fresh beef 显示文摘 | Chunyang Han Jianqing Wang Yang Li | 2014 | Meat Science2014，96，： | 1 |
| 12 | Rosuvastatin, Identified From a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer显示文摘 | Chunyang Wang Weiyang Tao Youdong Wang Jennifer Bikow Bingxin Lu Armand Keating Subodh Verma Thomas G. Parker Ruifa Han Xiao-Yan Wen | 2010 | European Urology2010，，3： | 1 |
| 13 | Bioinspired porous microspheres for sustained hypoxic exosomes release and vascularized bone regeneration显示文摘Exosomes derived from mesenchymal stem cells(MSCs)have demonstrated regenerative potential for cell-free bone tissue engineering,nevertheless,certain challenges,including the confined therapeutic potency of exosomes and ineffective delivery method,are still persisted.Here,we confirmed that hypoxic precondition could induce enhanced secretion of exosomes from stem cells from human exfoliated deciduous teeth(SHEDs)via comprehensive proteomics analysis,and the corresponding hypoxic exosomes(H-Exo)exhibited superior potential in promoting cellular angiogenesis and osteogenesis via the significant up-regulation in focal adhesion,VEGF signaling pathway,and thyroid hormone synthesis.Then,we developed a platform technology enabling the effective delivery of hypoxic exosomes with sustained release kinetics to irregular-shaped bone defects via injection.This platform is based on a simple adsorbing technique,where exosomes are adsorbed onto the surface of injectable porous poly(lactide-co-glycolide)(PLGA)microspheres with bioinspired polydopamine(PDA)coating(PMS-PDA microspheres).The PMS-PDA microspheres could effectively adsorb exosomes,show sustained release of H-Exo for 21 days with high bioactivity,and induce vascularized bone regeneration in 5-mm rat calvarial defect.These findings indicate that the hypoxic precondition and PMS-PDA porous microsphere-based exosome delivery are efficient in inducing tissue regeneration,hence facilitating the clinical translation of exosome-based therapy. | Yike Gao Zuoying Yuan Xiaojing Yuan Zhuo Wan Yingjie Yu Qi Zhan Yuming Zhao Jianmin Han Jianyong Huang Chunyang Xiong Qing Cai | 2022 | Bioactive Materials2022，7，8： | 1 |
| 14 | REACTION MECHANISM AND DYNAMICS OF PASTE BORONIZING IN A PLASMA显示文摘REACTIONMECHANISMANDDYNAMICSOFPASTEBORONIZINGINAPLASMALiChunyang,HanLimin,WangJian,LiuRuixian,TianjinUniversityAbstractThedis... | Li Chunyang, Han Limin ,Wang Jian, Liu Ruixian, Tianjin University | 1997 | Chinese Journal of Mechanical Engineering1997，10，2： | 0 |
| 15 | Classification of Arrhythmia Based on Convolutional Neural Networks and Encoder-Decoder Model显示文摘As a common and high-risk type of disease,heart disease seriously threatens people’s health.At the same time,in the era of the Internet of Thing(IoT),smart medical device has strong practical significance for medical workers and patients because of its ability to assist in the diagnosis of diseases.Therefore,the research of real-time diagnosis and classification algorithms for arrhythmia can help to improve the diagnostic efficiency of diseases.In this paper,we design an automatic arrhythmia classification algorithm model based on Convolutional Neural Network(CNN)and Encoder-Decoder model.The model uses Long Short-Term Memory(LSTM)to consider the influence of time series features on classification results.Simultaneously,it is trained and tested by the MIT-BIH arrhythmia database.Besides,Generative Adversarial Networks(GAN)is adopted as a method of data equalization for solving data imbalance problem.The simulation results show that for the inter-patient arrhythmia classification,the hybrid model combining CNN and Encoder-Decoder model has the best classification accuracy,of which the accuracy can reach 94.05%.Especially,it has a better advantage for the classification effect of supraventricular ectopic beats(class S)and fusion beats(class F). | Jian Liu Xiaodong Xia Chunyang Han Jiao Hui Jim Feng | 2022 | Computers, Materials & Continua2022，，10： | 0 |
| 16 | Two-dimensional tin diselenide nanosheets pretreated with an alkaloid for near-and mid-infrared ultrafast photonics显示文摘Two-dimensional(2D)tin diselenide(SnSe2),a novel layered material with excellent optical and electronic properties,has been extensively investigated in various promising applications,including photodetectors,optical switching,and ultrafast photonics.In this work,SnSe2 nanosheets have been obtained after pretreatment in an alkaloid,exhibiting high optical absorption and electron-enriched properties.Besides,the performances of the prepared SnSe2 in near-infrared(NIR)and mid-infrared(MIR)ultrafast photonics are presented.Notably,by employing the SnSe2-deposited microfiber device as a saturable absorber(SA)exhibiting typical nonlinear optical absorption properties,stable ultrashort pulses and rogue waves are realized in an erbium-doped fiber laser.Furthermore,the SnSe2-deposited SA device is also applied to a thulium-doped fiber laser to achieve stable ultrashort pulses.This study indicates that SnSe2 is expected to be a suitable candidate for ultrafast fiber lasers in the NIR and MIR regions. | Zhenhong Wang Bin Zhang Bing Hu Zhongjun Li Chunyang Ma Yu Chen Yufeng Song Han Zhang Jun Liu Guohui Nie | 2020 | Photonics Research2020，8，11： | 0 |
| 17 | Fault characteristics and control on hydrocarbon accumulation of middle-shallow layers in the slope zone of Mahu sag, Junggar Basin, NW China显示文摘The development, evolution and formation mechanism of faults and their control on the migration and accumulation of Mesozoic oil and gas in the middle-shallow layers of the slope zone of Mahu sag were studied by the interpretation of seismic and drilling data. Two types of faults, normal and strike-slip, are developed in the middle-shallow layers of the slope zone of the Mahu sag and they are mostly active in the Yanshanian period. They are divided into four grade faults: The grade I strike-slip faults with NWW to near EW direction are related to the left-lateral transpressive fault zones in the northwest of Junggar Basin since the end of the Triassic. The grade II faults with NE to NNE direction are the normal faults located at the junction of the fault zone and the slope zone, and their formation is related to the extension at the top of the nose-like structures in the fault zone. The grade III faults, which are also the normal faults, are the result of the extension at the top of the lower uplifts in the slope zone and differential compaction. The grade IV faults with NE direction are normal faults, which may be related to the extension environment at the tip of the lower uplifts. Faults not only are the channel for the vertical migration of oil and gas, but also control the oil-gas accumulation. There are two types of oil-gas reservoirs in the middle-shallow layers of slope zone of Mahu sag: fault block reservoirs and fault-lithologic reservoirs. They have large traps and promising exploration potential. | CHEN Yongbo CHENG Xiaogan ZHANG Han LI Chunyang MA Yongping WANG Guodong | 2018 | Petroleum Exploration and Development2018，45，6： | 0 |
| 18 | Protective effect of thioredoxin on hippocampal neurons induced by high glucose in mice显示文摘Varying degrees of central systemneurolopathic involvement induced by diabetes mellitus(DM)contributes to cognitive decline,is known as diabetic encephalopathy(DE),which is also one of the independent risk factors of Alzheimer's disease(AD).This study aims to investigate whether thioredoxin(Trx)could alleviate DE and AD through endoplasmic reticulum stress(ERS),antioxidant stress and apoptosis signaling pathway. | Guo Yu Han Ying Wang Chunyang Kong Li Ma Haiying | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 19 | On the origins and evolution of phytohormone signaling and biosynthesis in plants显示文摘Phytohormones modulate nearly all aspects of plant biology.Phytohormone signaling and biosynthesis pathways have been characterized mainly through studies of angiosperms,particularly the model plant Arabidopsis thaliana(Blázquez et al.,2020).Phylogenetic analyses across plants provide insights into the origins and evolution of phytohormone signaling pathways(Wang et al.,2015).However,these studies come with one caveat:homology at the level of sequences does not necessarily demonstrate functional conservation.Due to the lack of functional verification,much remains obscure and contentious about the origins of phytohormone signaling and biosynthesis pathways.In a recent study,Jia et al.,2023 employed a combined approach of phylogenetic analysis and functional characterization to explore the origin and evolution of the signaling and biosynthesis pathways of salicylic acid(SA),a crucial plant defense hormone. | Chunyang Wang Zhen Gong Guan-Zhu Han | 2023 | Molecular Plant2023，16，3： | 0 |
| 20 | Study on Functional Mechanical Performance of Honeycomb Array Structures Inspired by Gideon Beetle显示文摘To obtain bio-inspired structures with superior biological function,four bio-inspired structures named regular arrangement honeycomb structure(RAHS),staggered arrangement honeycomb structure(SAHS),floral arrangement honeycomb structure(FLAHS)and functional arrangement honeycomb structure(FUAHS)are designed by observing the microstructure of the Gideon beetle,based on the optimal size bio-inspired cells by response surface method(RSM)and particle swarm optimization(PSO)algorithm.According to Euler theory and buckling failure theory,compression deformation properties of bio-inspired structures are explained.Experiments and simulations further verify the accuracy of theoretical analysis results.The results show that energy absorption of FLAHS is,respectively,increased by 26.95%,22.85%,and 121.45%,compared with RAHS,SAHS,and FUAHS.Elastic modulus of FLAHS is 110.37%,110.37%,and 230.56% of RAHS,SAHS,and FUAHS,respectively.FLAHS perfectly inherits crashworthiness and energy absorption properties of the Gideon beetle,and FLAHS has the most stable force.Similarly,RAHS,SAHS,and FUAHS,respectively,inherit mechanical properties of the Gideon beetle top horn,the Gideon beetle middle horn,and the abdomen of the beetle.This method,designing bio-inspired structures with biological functions,can be introduced into the engineering field requiring the special function. | Ruiyao Liu Guofeng Yao Zezhou Xu Xue Guo Kuiyang Gao Qing Cao Zhenglei Yu Zhihui Zhang Chunyang Han Jiabao Liu | 2022 | Journal of Bionic Engineering2022，19，4： | 0 |
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