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| 1 | Radiofrequency ablation or microwave ablation combined with transcatheter arterial chemoembolization in treatment of hepatocellular carcinoma by comparing with radiofrequency ablation alone显示文摘Objective:To compare radiofrequency ablation(RFA) or microwave ablation(MWA) and transcatheter arterial chemoembolization(TACE) with RFA or MWA monotherapy in hepatocellular carcinoma(HCC).Methods:A prospective,randomized,controlled trial was conducted on 94 patients with HCC ≤7 cm at a single tertiary referral center from June 2008 to June 2010 at the Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Southeast University.The patients were randomly assigned into the TACERFA or TACE-MWA(combined treatment group) and the RFA-alone or MWA-alone groups(control group).The primary end point was overall survival.The secondary end point was recurrence-free survival,and the tertiary end point was adverse effects.Results:Until the time of censor,17 patients in the TACE-RFA or TACE-MWA group had died.The median follow-up time of the patients who were still alive for the TACE-RFA or TACE-MWA group was 47.5±11.3 months(range,29 to 62 months).The 1-,3- and 5-year overall survival for the TACE-RFA or TACE-MWA group was 93.6%,68.1% and 61.7%,respectively.Twenty-five patients in the RFA or MWA group had died.The median follow-up time of the patients who were still alive for the RFA or MWA group was 47.0±12.9 months(range,28 to 62 months).The 1-,3- and 5-year overall survival for the RFA or MWA group was 85.1%,59.6% and 44.7%,respectively.The patients in the TACE-RFA or TACE-MWA group had better overall survival than the RFA or MWA group [hazard ratio(HR),0.526;95% confidence interval(95% CI),0.334-0.823;P=0.002],and showed better recurrence-free survival than the RFA or MWA group(HR,0.582;95% CI,0.368-0.895;P=0.008).Conclusions:RFA or MWA combined with TACE in the treatment of HCC ≤7 cm was superior to RFA or MWA alone in improving survival by reducing arterial and portal blood flow due to TACE with iodized oil before RFA. | Yongxiang Yi Yufeng Zhang Qiang Wei Liang Zhao Jianbo Han Yan Song Ying Ding Guilan Lu Junmao Liu Huaiying Ding Feng Dai Xiaojun Tang | 2014 | Chinese Journal of Cancer Research2014，26，1： | 29 |
| 2 | Change of asphaltene and resin properties after catalytic aquathermolysis显示文摘Resin and asphaltene were separated from Liaohe heavy oil. Catalytic aquathermolysis of asphaltene and resin was investigated by using water soluble catalysts (NiSO4 and FeSO4) and oil soluble catalysts (nickel naphthenate and iron naphthenate). Before and after aquathermolysis, the properties of the resin and asphaltene was compared by means of ultimate analysis, vapor pressure osmometer (VPO) average molecular weight, X-ray diffraction (XRD), 13C and 1H nuclear magnetic resonance (NMR). The conversion sequence was as follows: No-catalyst | Yi Yufeng Li Shuyuan Ding Fuchen Yu Hang | 2009 | Petroleum Science2009，6，2： | 12 |
| 3 | Chemical vapor deposition growth of large-scale hexagonal boron nitride with controllable orientation显示文摘有一致厚度的大域的六角形的硼氮化物(h-BN ) 的化学蒸汽免职(CVD ) 合成是很挑战性的,主要由于这材料的极其高的成核密度。此处,我们报导晶片规模的成功的生长,有大单人赛水晶的领域尺寸的高质量的 h-BN 单层电影,吗直到~ 72 ??????????????????????????慮潮档湡敮獬???????慮潮畴敢??洠獥灯牯???? ?? | Xiuju Song Junfeng Gao Yufeng Nie Teng Gao Jingyu Sun Donglin Ma Qiucheng Li Yubin Chen Chuanhong Jin Alicja Bachmatiuk Mark H. Rummeli Feng Ding Yanfeng Zhang Zhongfan Liu | 2015 | Nano Research2015，8，10： | 12 |
| 4 | CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta,alpha,beta,and gamma显示文摘SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape,compromising the effectiveness of existing vaccines and neutralizing antibodies.An in-depth investigation on COVID-19 pathogenesis is urgently needed to develop a strategy against SARS-CoV-2 variants.Here,we identified CD147 as a universal receptor for SARS-CoV-2 and its variants.Meanwhile,Meplazeumab,a humanized anti-CD147 antibody,could block cellular entry of SARS-CoV-2 and its variants-alpha,beta,gamma,and delta,with inhibition rates of 68.7,75.7,52.1,52.1,and 62.3%at 60μg/ml,respectively.Furthermore,humanized CD147 transgenic mice were susceptible to SARS-CoV-2 and its two variants,alpha and beta.When infected,these mice developed exudative alveolar pneumonia,featured by immune responses involving alveoli-infiltrated macrophages,neutrophils,and lymphocytes and activation of IL-17 signaling pathway.Mechanistically,we proposed that severe COVID-19-related cytokine storm is induced by a'spike protein-CD147-CyPA signaling axis':Infection of SARS-CoV-2 through CD147 initiated the JAK-STAT pathway,which further induced expression of cyclophilin A(CyPA);CyPA reciprocally bound to CD147 and triggered MAPK pathway.Consequently,the MAPK pathway regulated the expression of cytokines and chemokines,which promoted the development of cytokine storm.Importantly,Meplazumab could effectively inhibit viral entry and inflammation caused by SARS-CoV-2 and its variants.Therefore,our findings provided a new perspective for severe COVID-19-related pathogenesis.Furthermore,the validated universal receptor for SARS-CoV-2 and its variants can be targeted for COVID-19 treatment. | Jiejie Geng Liang Chen Yufeng Yuan Ke Wang Youchun Wang Chuan Qin Guizhen Wu Ruo Chen Zheng Zhang Ding Wei Peng Du Jun Zhang Peng Lin Kui Zhang Yongqiang Deng Ke Xu Jiangning Liu Xiuxuan Sun Ting Guo Xu Yang Jiao Wu Jianli Jiang Ling Li Kun Zhang Zhe Wang Jing Zhang Qingguo Yan Hua Zhu Zhaohui Zheng Jinlin Miao Xianghui Fu Fengfan Yang Xiaochun Chen Hao Tang Yang Zhang Ying Shi Yumeng Zhu Zhuo Pei Fei Huo Xue Liang Yatao Wang Qingyi Wang Wen Xie Yirong Li Mingyan Shi Huijie Bian Ping Zhu Zhi-Nan Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 6 |
| 5 | A high-Tc dc-SQUID-based single-channel MCG and its performance显示文摘A single-channel high-Tc dc-SQUID magnetometer and gradiometer have been developed to record the magnetic field component perpendicular to the human chest generated by heart-beat. Magnetocardiogram (MCG) measurements have been carried out inside a magnetically shielded room. By sequentially adjusting a non-magnetic patient table with 5 cm pitch in X and Y directions, the field signals on a rectangle grid 5×5 over the chest area were registered in real time trace point by point with a typical dwell time over 30 cardiocycles each. Utilizing standard electrocardiogram (ECG) recordings as timing reference measured simultaneously with the MCG signals, the MCG data were then averaged and combined to form magnetic field patterns every 10 ms or so. Both the current dipole, which is parallel to MCG measuring plane and produces the vertical magnetic field, and its depth were determined as a function of time in a standard way. We have compared the MCG of healthy hearts with that of a heart with right bundle | WANG Huiwu DING Hongsheng ZHANG Lihua HUANG Xuguang CHEN Weichang WANG Ziqiang FENG Ji LIU Yiping ZHAO Shiping REN Yufeng YU Hongwei XU Fengzhi WANG Xiaoyin CHEN Genghua YANG Qiansheng | 2002 | Chinese Science Bulletin2002，47，22： | 2 |
| 6 | Effective shape-controlled synthesis of gallium selenide nanosheets by vapor phase deposition显示文摘The controlled synthesis of large and uniform gallium selenide(GaSe)crystals is crucial for its various applications based on the attractive properties of this emerging material.In this work,vapor phase growth of high-quality monolayer GaSe nanosheets with multiple shape and size is achieved by tuning the Ga/GaSe ratio in the precursor.A theoretical model based on density functional theory calculations and kinetic Wulff construction theory describe the observed shape evolution of the GaSe nanosheets.Results show that the Ga/Se ratio plays a critical role in the evolution of the domain shape and size.Moreover,the as-grown GaSe nanosheets show improved performance with photoresponse time less than 0.7 ms and responsibility up to 3,000 AW.This study presents a previously unexplored strategy for the controlled growth of two-dimensional(2D)GaSe nanosheets for promising applications in next-generation optoelectronics. | Lilan Tan Qingbo Liu Yufeng Ding Xiaogang Lin Wei Hu Meng-Qiu Cai Hong Zhou | 2020 | Nano Research2020，13，2： | 2 |
| 7 | Responses of the Sea Surface Temperature and Suspended Matter Concentration to ENSO Events in the Bohai Sea显示文摘The sea surface temperature(SST)and sea surface suspended matter concentration data in the Bohai Sea were collected by multiple NOAA satellites from 1985 to 2018.The background calibration method was used to correct the systematic errors caused by the long-term observations through multiple NOAA satellites in this paper.Then,we studied the long-term variations of the sea surface temperature(SST)and sea surface suspended matter concentration(SSC)and their response to ENSO events in the Bohai Sea.Our results show that the SST and SSC of the Bohai Sea have been increasing since 1985,with an average rate of 0.04℃per year for SST,which is higher than the global average.The average increasing rate of SSC was 0.51 mg L^(-1)yr^(-1),which may be mainly due to the enhancement of winter monsoon in the Bohai.In winter,the SST and SSC of the Bohai Sea were higher in El Niño years than in La Niña years.In El Niño years,the ocean circulations were the main factor affecting the variation in SST.The robust circulation system caused by the strong winter monsoon enhances the water exchange between the cold water of the Bohai Sea and the warm water of the Yellow Sea,resulting in a higher SST in La Niña years.In summer,the SSTs of the Bohai Sea were lower in El Niño years than those in the La Niña years because of the decrease of the SST in the Western Pacific Ocean,the weakening of the subtropical high in the western Pacific,and its eastward shift caused by the El Niño events. | LIU Xue DING Dong LI Guangxue ZHANG Yang LIU Shidong WANG Nan ZHONG Yi YANG Xue PAN Yufeng YU Di ZHANG Lei XUE Wenjing | 2023 | Journal of Ocean University of China2023，22，3： | 1 |
| 8 | Learning and scientific reasoning显示文摘 | Lei Bao Tianfan Cai Kathy Koenig Kai Fang Jing Han Jing Wang Qing Liu Lin Ding Lili Cui Ying Luo Yufeng Wang Lieming Li & Nianle Wu | 2009 | Science2009，323，： | 1 |
| 9 | Collaborative manufacturing technologies of structure shape and surface integrity for complex thin-walled components of aero-engine:Status,challenge and tendency显示文摘Presently,the service performance of new-generation high-tech equipment is directly affected by the manufacturing quality of complex thin-walled components.A high-efficiency and quality manufacturing of these complex thin-walled components creates a bottleneck that needs to be solved urgently in machinery manufacturing.To address this problem,the collaborative manufacturing of structure shape and surface integrity has emerged as a new process that can shorten processing cycles,improve machining qualities,and reduce costs.This paper summarises the research status on the material removal mechanism,precision control of structure shape,machined surface integrity control and intelligent process control technology of complex thin-walled components.Numerous solutions and technical approaches are then put forward to solve the critical problems in the high-performance manufacturing of complex thin-wall components.The development status,challenge and tendency of collaborative manufacturing technologies in the high-efficiency and quality manufacturing of complex thin-wall components is also discussed. | Biao ZHAO Wenfeng DING Zhongde SHAN Jun WANG Changfeng YAO Zhengcai ZHAO Jia LIU Shihong XIAO Yue DING Xiaowei TANG Xingchao WANG Yufeng WANG Xin WANG | 2023 | Chinese Journal of Aeronautics2023，36，7： | 1 |
| 10 | Large-area flexible and transparent UV photodetector based on cross-linked Ag NW@ZnO NRs with high performance显示文摘A series of large-area,flexible and transparent ultraviolet(UV)photodetectors(PDs)based on Ag nanowire(NW)@ZnO nanorods(NRs)are fabricated by an inexpensive,facile and effective approach.These Ag NW@ZnO NRs are successfully synthesized using a two-step method in an oil bath with a high surface-to-volume ratio and good crystallinity.The PDs are fabricated by drop-coating with different drop-coating times on the surface of polyethylene terephthalate(PET)coupled with Au electrodes.By optimizing the cross-linked network of Ag NW@ZnO NRs,PD2 with a size greater than 25 mm exhibits excellent photoresponse under UV light illumination of 365 nm(1.3 m W cm^(-2))with a bias of 5 V:a high sensitivity of over 10^(3),and a much shorter rise/decay time of 2.6 s/2.3 s.Simultaneously,the detector exhibits an average transmittance of more than 70%in the visible light region,as well as good flexibility and excellent mechanical stability under a bending angle of 120°over 1000 circles bending.These integral advantages have significant potential for practical applications and mass production. | Lin Zhang Nuomei Li Qiuchen Ma Jiahui Ding Chuang Chen Zhaocheng Hu Weiwei Zhao Yufeng Li Huanhuan Feng Mingyu Li Hongjun Ji | 2022 | Journal of Materials Science & Technology2022，，15： | 1 |
| 11 | The importance of proleptic branch traits in biomass production of poplar in high-density plantations显示文摘Branch phenotypic traits determine tree crown architecture,which in turn governs leaf display,light interception,and biomass production.Sylleptic and proleptic branches are the obviously different branch phenotypes in the poplar crown.Many studies have focused on the influence of sylleptic branch numbers(SBN)on biomass production,but the research on the influence of proleptic branch phenotypes was only a few.To explore the relationship between proleptic branch traits and biomass generation production in a high-density poplar plantation,we investigated the branch phenotypic traits of three poplar genotypes,all of which have high survival rates in forests(>95%)and significantly different crown architecture and biomass performance in the high-density plantations(1667 stems ha−1).The plantation site was established in 2007.A terrestrial laser scanner was used to measure branch characteristics such as length,angle of origin and termination,and azi-muth angle.A hierarchical cluster analysis performed on branch characteristics showed that SBN,crown depth,and proleptic branch curvature(PBC)were clustered with bio-mass production and leaf area index(LAI).Among all of the monitored traits,PBC played the second most important role in biomass production after SBN and was significantly correlated with SBN,LAI,and biomass production.The positive correlation between PBC and SBN indicated that a larger PBC was associated with more sylleptic branches within the monitored genotypes planted in the high-density plantation,providing greater leaf area and biomass produc-tion.The results of this study will improve the identification of high-production poplar varieties for cultivation in high-density plantations for biofuel production. | Changjun Ding Ningning Wang Qinjun Huang Weixi Zhang Juan Huang Suli Yan Boyi Chen Dejun Liang Yufeng Dong Yingbai Shen Xiaohua Su | 2022 | Journal of Forestry Research2022，33，2： | 1 |
| 12 | Modeling and application on optimal-selection evaluation for manufac turing grid resource显示文摘 | DING Yufeng TAO Fei SHENG Buyun | 2008 | International Journal of Computer In- tegrated Manufacturing2008，21，1： | 1 |
| 13 | Quantitative Evaluation Research on Uncertainty Factors in Production Scheduling of Manufacturing Enterprises显示文摘Shop scheduling problem is core part and research hot in modern manufacture system,it has important meaning for decreasing operating costs,shortening production period and so on.Based on shop scheduling problems,this paper mainly dis- cuss and classify uncertainty factors of the shop scheduling,Meanwhile set up corresponding reliability evaluation model according to some uncertainty factors,and so it can better direct shop scheduling. | WU Bo SHI Guoxin DING Yufeng JIANG Zhengfeng (School of Mechanical and Electronic Engineering,WuHan University of Technology,Wnhan 430070,China | 2006 | 武汉理工大学学报2006，28，S2： | 1 |
| 14 | Elevated nuclear PIGL disrupts the cMyc/BRD4 axis and improves PD-1 blockade therapy by dampening tumor immune evasion显示文摘To improve the efficacy of lenvatinib in combination with programmed death-1(PD-1)blockade therapy for hepatocellular carcinoma(HCC),we screened the suppressive metabolic enzymes that sensitize HCC to lenvatinib and PD-1 blockade,thus impeding HCC progression.After analysis of the CRISPR‒Cas9 screen,phosphatidylinositol-glycan biosynthesis class L(PIGL)ranked first in the positive selection list.PIGL depletion had no effect on tumor cell growth in vitro but reprogrammed the tumor microenvironment(TME)in vivo to support tumor cell survival.Specifically,nuclear PIGL disrupted the interaction between cMyc/BRD4 on the distant promoter of target genes and thus decreased the expression of CCL2 and CCL20,which are involved in shaping the immunosuppressive TME by recruiting macrophages and regulatory T cells.PIGL phosphorylation at Y81 by FGFR2 abolished the interaction of PIGL with importinα/β1,thus retaining PIGL in the cytosol and facilitating tumor evasion by releasing CCL2 and CCL20.Clinically,elevated nuclear PIGL predicts a better prognosis for HCC patients and presents a positive correlation with CD8+T-cell enrichment in tumors.Clinically,our findings highlight that the nuclear PIGL intensity or the change in PIGL-Y81 phosphorylation should be used as a biomarker to guide lenvatinib with PD-1 blockade therapy. | Hua Yu Tiezhu Shi Linli Yao Dongwei Xu Yufeng Ding Qiang Xia Wei Liu Xiongjun Wang | 2023 | Cellular & Molecular Immunology2023，20，8： | 1 |
| 15 | A white light emitting luminescent material Ba33Y(PO4)3:Dy+显示文摘 | LIU Qingbo LIU Yufeng DING Yanjun | 2014 | Ceramics International2014，40，10： | 1 |
| 16 | An efficient charge compensa- ted red phosphor SraWO6:K+ , Eua+-{or white LEDs显示文摘 | Xin Zhao Yufeng Ding | 2013 | Journal of Alloys and Compounds2013，553，22： | 1 |
| 17 | Test Technology Course Experiment Reformation Based on Virtual Instrument Experiment Platform显示文摘 | Yufeng Ding Yong-Feng WU | 2016 | 教育研究前沿(中英文版)2016，6，4： | 0 |
| 18 | Fertility outcome analysis after modified laparoscopic microsurgical tubal anastomosis显示文摘Modified laparoscopic microsurgical tubal anastomosis is an alternative for microsurgical anastomosis via laparotomy to reverse sterilization in women with renewed child wish.The current study aims to evaluate the fertility outcome after modified laparoscopic microsurgical tubal anastomosis.A retrospective study was performed.Fifty-eight women who underwent modified laparoscopic microsurgical tubal anastomosis were monitored to investigate the fertility outcome and characteristics of this new technology.Of the 58 patients,the cumulative pregnancy rate(PR)in the 42 patients with follow-up data was 23.8%(10/42),57.1%(24/42),66.7%(28/42),and 73.8%(31/42)within 6,12,24,and 36 months after surgery,respectively.The intrauterine PR was 69.0%(29/42).Two patients(4.8%)had ectopic pregnancies that occurred within 24 months of surgery;three cases ended in spontaneous abortion.The delivery rate was 83.9%(26/31).The length of operating time was 1.20.3 h,with a range of 1.0–2.5 h(60–145 min),and the mean time was approximately 75 min.The blood loss was relatively small,between 10 and 50 ml with an average amount of 22 ml.Thus,the modified laparoscopic tubal anastomosis is a highly successful procedure and a viable alternative to open abdominal microsurgical approaches.Compared with the traditional laparoscopic tubal sterilization reversal,this modified approach has three advantages:(1)less invasive approach via a trocar reduction;(2)remodeling of tube is better performing tied together after 3–4 sutures;and(3)faster operating time. | Jihui Ai Pei Zhang Lei Jin Yufeng Li Jing Yue Ding Ma Hanwang Zhang | 2011 | Frontiers of Medicine2011，5，3： | 0 |
| 19 | 气候因子对中国黄土高原植被物候的时间效应显示文摘研究植被生长季的开始(SOS)和结束(EOS)可以改善气候变化下的植被预测。气候因素对植被生长具有时间效应,包括无时间效应(no)、时滞效应(lag)、时间累积效应(acc)以及时滞和累积效应(lagacc)。该研究建立黄土高原(Loess Plateau,LP)SOS/EOS与气候因子的线性回归方程,分析了4种时间效应情景下单个和多个气候因子对植被物候的影响,并研究了lagacc情景下植被物候对气候因子时间滞后和时间累积效应的响应。研究结果表明,在4种时间效应中,lagacc最大程度地解释了气候对植被物候的影响,是在LP上模拟植被物候与气候关系的最佳时间效应。此外,在不同的时间效应和植被类型中,多重气候因子的解释度高于单一气候因子,同时考虑多种气候因素提高了它们对植被物候影响的可预测性。在lagacc条件下,SOS对温度(TMP)和降水(PRE)的响应在整个LP中分别表现为1.44±0.43/3.49±0.85和1.38±0.30/3.38±0.71个月的滞后/累积,EOS对TMP和PRE的响应分别表现为1.35±0.17/2.37±0.34和1.59±0.19/4.16±0.50个月的滞后/累积。这些结果说明,在建立气候因素与植被物候之间的关系时,需要考虑lagacc和多种气候因素。 | Ning Liu Yufeng Shi Yongxia Ding Li Liu Shouzhang Peng | 2023 | Journal of Plant Ecology2023，16，2： | 0 |
| 20 | Methanol Distillation System: Process Analysis and Column Design显示文摘Base on industrial research and experience, the process of methanol distillation is analyzed,and above all, a new concept of high pressure flowsheet and low pressure flowsheet is defined. The new configuration helps to handle problems encountered in many factories in China. The inter influence between process and column internal pattern is also pointed out. Recommendation of new column internal designs is given. Finally, industrial examples tell the how the new concept works and the possibility of combining process to give more opens to solve engineering problems. | Sun Jinsheng Tian Yufeng Xu Shimin Ding Hui Wang Tao Li Xingang Zheng Yanmei | 2005 | 化工进展2005，24，z1： | 0 |
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