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| 1 | Involvement of CsWRKY70 in salicylic acid-induced citrus fruit resistance against Penicillium digitatum显示文摘Penicillium digitatum causes serious losses in postharvest citrus fruit.Exogenous salicylic acid(SA)can induce fruit resistance against various pathogens,but the mechanism remains unclear.Herein,a transcriptome-based approach was used to investigate the underlying mechanism of SA-induced citrus fruit resistance against P.digitatum.We found that CsWRKY70 and genes related to methyl salicylate(MeSA)biosynthesis(salicylate carboxymethyltransferase,SAMT)were induced by exogenous SA.Moreover,significant MeSA accumulation was detected in the SA-treated citrus fruit.The potential involvement of CsWRKY70 in regulating CsSAMT expression in citrus fruit was studied.Subcellular localization,dual luciferase,and electrophoretic mobility shift assays and an analysis of transient expression in fruit peel revealed that the nucleus‐localized transcriptional activator CsWRKY70 can activate the CsSAMT promoter by recognizing the W-box element.Taken together,the findings from this study offer new insights into the transcriptional regulatory mechanism of exogenous SA-induced disease resistance in Citrus sinensis fruit. | Bing Deng Wenjun Wang Changqing Ruan Lili Deng Shixiang Yao Kaifang Zeng | 2020 | Horticulture Research2020，7，1： | 6 |
| 2 | Tensile and fracture properties of Ti-62A alloy plate with different microstructures显示文摘Ti-62A alloy plates with three different types of microstructure, fully equiaxed, bimodal, and Widmanst tten, were obtained by various heat treatments to investigate the effects of microstructure on the tensile and fracture properties at room temperature. The results reveal that Widmanst tten microstructure exhibits good damage tolerance behavior considering strength, fracture toughness, and fatigue crack growth behavior, while the bimodal microstructure shows good comprehensive properties considering the plasticity synthetically. Optical microscopy (OM) and scanning electron microscopy (SEM) microstructure analyses on fracture and fatigue crack path demonstrate that the dependence of mechanical properties and fatigue crack growth behavior on microstructural feature are attributed to the α lamellae width and the α colony size. | LIU Rui HUI Songxiao YE Wenjun YU Yang FU Yanyan SONG Xiaoyun DENG Xiguang | 2012 | Rare Metals2012，31，5： | 5 |
| 3 | A preliminary analysis of the surface chemistry of atmospheric aerosol particles in a typical urban area of Beijing显示文摘Atmospheric aerosol particle samples were collected using an Ambient Eight Stage(Non-Viable) Cascade Impactor Sampler in a typical urban area of Beijing from 27 th Sep.to 5th Oct.,2009.The surface chemistry of these aerosol particles was analyzed using Static Time of Flight-Secondary Ion Mass Spectrometry(Static TOF-SIMS).The factors influencing surface compositions were evaluated in conjunction with the air pollution levels,meteorological factors,and air mass transport for the sampling period.The results show that a variety of organic ion groups and inorganic ions/ion groups were accumulated on the surfaces of aerosol particles in urban areas of Beijing;and hydrophobic organic compounds with short-or middle-chain alkyl as well as hydrophilic secondary inorganic compounds were observed.All these compounds have the potential to affect the atmospheric behavior of urban aerosol particles.PM1.1–2.1and PM3.3–4.7had similar elements on their surfaces,but some molecules and ionic groups demonstrated differences in Time of Flight-Secondary Ion Mass Spectrometry spectra.This suggests that the quantities of elements varied between PM1.1–2.1and PM3.3–4.7.In particular,more intense research efforts into fluoride pollution are required,because the fluorides on aerosol surfaces have the potential to harm human health.The levels of air pollution had the most significant influence on the surface compositions of aerosol particles in our study.Hence,heavier air pollution was associated with more complex surface compositions on aerosol particles.In addition,wind,rainfall,and air masses from the south also greatly influenced the surface compositions of these urban aerosol particles. | Zhengzheng Zhang Hong Li Hongyan Liu Runxiang Ni Jinjuan Li Liqun Deng Defeng Lu Xueli Cheng Pengli Duan Wenjun Li | 2016 | Journal of Environmental Sciences2016，28，9： | 5 |
| 4 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 5 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 6 | Fluorination-substitution effect on all-small-molecule organic solar cells显示文摘Due to the strong crystallinity and anisotropy of small molecules, matched molecular photoelectric properties and morphologies between small molecules and non-fullerene acceptors are especially important in all-small-molecule organic solar cells(OSCs).Introducing fluorine atoms has been proved as an effective strategy to achieve a high device performance through tuning molecular energy levels, absorption and assembly properties. Herein, we designed a novel benzodithiophene-based small molecule donor BDTF-CA with deep highest occupied molecular orbital(HOMO) energy level. All-small-molecule OSCs were fabricated by combing non-fullerene acceptor IDIC with different fluorine-atom numbers. Two or four fluorine atoms were introduced to the end-capped acceptor of IDIC, which are named as IDIC-2 F and IDIC-4 F, respectively. With the increase of fluorination from IDIC to IDIC-4 F, the open circuit voltage(Voc) of the devices decreased, while hole and electron mobilities of the active layers increased by one order of magnitude. Contributed to the most balanced Voc, short-circuit current(Jsc) and fill factor(FF), the device based on BDTF-CA/IDIC-2 F achieved the highest power conversion efficiency of 9.11%. | Qiong Wu Dan Deng Jianqi Zhang Wenjun Zou Yang Yang Zhen Wang Huan Li Ruimin Zhou Kun Lu Zhixiang Wei | 2019 | Science China Chemistry2019，62，7： | 3 |
| 7 | Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importinα7 is counteracted by TBK1-p62 axis-mediated autophagy显示文摘As a major component of the viral ribonucleoprotein(vRNP)complex in influenza A virus(IAV),nucleoprotein(NP)interacts with isoforms of importinαfamily members,leading to the import of itself and vRNP complex into the nucleus,a process pivotal in the replication cycle of IAV.In this study,we found that BinCARD1,an isoform of Bcl10-interacting protein with CARD(BinCARD),was leveraged by IAV for efficient viral replication.BinCARD1 promoted the nuclear import of the vRNP complex and newly synthesized NP and thus enhanced vRNP complex activity.Moreover,we found that BinCARD1 interacted with NP to promote NP binding to importinα7,an adaptor in the host nuclear import pathway.However,we also found that BinCARD1 promoted RIG-I-mediated innate immune signaling by mediating Lys63-linked polyubiquitination of TRAF3,and that TBK1 appeared to degrade BinCARD1.We showed that BinCARD1 was polyubiquitinated at residue K103 through a Lys63 linkage,which was recognized by the TBK1-p62 axis for autophagic degradation.Overall,our data demonstrate that IAV leverages BinCARD1 as an important host factor that promotes viral replication,and two mechanisms in the host defense system are triggered—innate immune signaling and autophagic degradation—to mitigate the promoting effect of BinCARD1 on the life cycle of IAV. | Xuyuan Wang Li Jiang Guangwen Wang Wenjun Shi Yuzhen Hu Bo Wang Xianying Zeng Guobin Tian Guohua Deng Jianzhong Shi Liling Liu Chengjun Li Hualan Chen | 2022 | Cellular & Molecular Immunology2022，19，10： | 3 |
| 8 | Construction of the Chinese Veteran Clinical Research (CVCR) Platform for the assessment of non-communicable diseases显示文摘 | Tan Jiping Li Nan Gao Jing Guo Yuhe Hu Wei Yang Jinsheng Yu Baocheng Yu Jianmin Du Wei Zhang Wenjun Cui Lianqi Wang Qingsong Xia Xiangnan Li Jianjun Zhou Peiyi Zhang Baohe Liu Zhiying Zhang Shaogang Sun Lanying Liu Nan Deng Ruixiang Dai Wenguang Yi Fang Chen Wenjun Zhang Yongqing Xue Shenwu Cui Bo Zhao Yiming Wang Luning | 2014 | Chinese Medical Journal2014，，3： | 3 |
| 9 | A-π-D-π-A small-molecule donors with different end alkyl chains obtain different morphologies in organic solar cells显示文摘For bulk-heterojunction organic solar cells, the morphology of the blend films highly influence the exciton dissociation and charge transport process. In this work, two novel A-π-D-π-A(A represents the acceptor unit and D represents the donor unit) backbone structure small molecular electron donors based on two dimensional conjugated naphtho[1,2-b:5,6-b']dithiophene(NDT) with different end alkyl chains, named as NDT-3T-EH and NDT-3T-O, have been designed and synthesized. The photovoltaic property of NDT-3T-O-based device is better than that of the NDT-3T-EH and the best efficiency reaches 7.06%, and the photovoltaic property of NDT-3T-EH reaches 6.11%. The difference in the performance should be attributed to the different morphology and phase separation resulted from the different crystallinity and aggregation ability of two donors. The results demonstrate that the optimized end alkyl chains can be used to design A-π-D-π-A backbone structure small molecular electron donors for smallmolecule organic solar cells. | Yanan Shi Chen Yang Huan Li Lixuan Liu Ruimin Zhou Wenjun Zou Zhen Wang Qiong Wu Dan Deng Jianqi Zhang Kun Lu Zhixiang Wei | 2019 | Chinese Chemical Letters2019，30，4： | 3 |
| 10 | Stable confinement of Fe/Fe_(3)C in Fe,N-codoped carbon nanotube towards robust zinc-air batteries显示文摘Catalytic oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)have garnered great attention as the key character in metal-air batteries.Herein,we developed a superior nonprecious bifunctional oxygen electrocatalyst,fabricated through spatial confinement of Fe/Fe_(3)C nanocrystals in pyridinic N and Fe-Nx rich carbon nanotubes(Fe/Fe_(3)C-N-CNTs).During ORR,the resultant electrocatalyst exhibits positive onset pote ntial of 1.0 V(vs.RHE),large half-wave potentials of 0.88 V(vs.RHE),which is more positive than Pt/C(0.98 V and 0.83 V,respectively).Remarkably,Fe/Fe_(3)C-N-CNTs exhibits outstanding durability and great methanol tolerance,exceeding Pt/C and most reported nonprecious metal-based oxygen reduction electrocatalysts.Moreover,Fe/Fe_(3)C-N-CNTs show a markedly low potential at j=10 mA/cm^(2),small Tafel slopes and extremely high stability for OER.Impressively,the Fe/Fe_(3)C-N-CNTs-based Zn-air batteries demonstrate high power density of 183 mW/cm^(2)and robust charge/discharge stability.It is revealed that the spatial confinement effect can impede the aggregation and corrosion of Fe/Fe_(3)C nanocrystals.Meanwhile,Fe/Fe_(3)C and Fe-Nx play synergistic effect on boosting the ORR/OER activity,which provides an important guideline for construction of inexpensive nonprecious metal-carbon hybrid nanomaterials. | Lingbo Zong Xin Chen Shuming Dou Kaicai Fan Zumin Wang Wenjun Zhang Yunmei Du Jie Xu Xiaofei Jia Qi Zhang Xia Li Yida Deng Yanan Chen Lei Wang | 2021 | Chinese Chemical Letters2021，32，3： | 2 |
| 11 | Producing nanocrystalline materials by machining 显示文摘 | Deng Wenjun Wan Zhenping Zhao Xiaolin | 2007 | Acta Scientiarum Naturalium Universitatis Sunyatsen I2007，46，6： | 1 |
| 12 | Isolation and characterization of endophytic fungi from Camptotheca acuminata显示文摘 | Xiaowei Ding Kaihui Liu Baiwan Deng Wenqiang Chen Wenjun Li Feihu Liu | 2013 | World Journal of Microbiology and Biotechnology2013，，10： | 1 |
| 13 | PM 2.5 -induced oxidative stress triggers autophagy in human lung epithelial A549 cells显示文摘 | Xiaobei Deng Fang Zhang Wei Rui Fang Long Lijuan Wang Zhaohan Feng Deliang Chen Wenjun Ding | 2013 | Toxicology in Vitro2013，，6： | 1 |
| 14 | Effect of Yupingfeng Polysaccharide on Serum IL-2 and IFN-γ Levels in Immunosuppressive Mice显示文摘[Objective] The paper was to discuss regulation and protection effect of Yupingfeng polysaccharide( YPF-P) on immunosuppressive mice. [Method]Taking immunosuppressive mice induced by 80 mg / kg cyclophosphamide as test animal model,effects of different doses( 100,200 and 400 mg / kg) of YPF-P on spleen index,serum IL-2 and IFN-γ levels of mice were studied. [Result] High dose of YPF-P( 400 mg / kg) could improve the spleen index of immunosuppressive mice( P < 0. 05). YPF-P could enhance serum IL-2 and IFN-γ levels of immunosuppressive mice,and the effects in middle-dose group and low-dose group were better. YPF-P could significantly increase serum IL-2 level of normal mice( P < 0. 01),but it had no significant effect on serum IFN-γ level of normal mice.[Conclusion]The research provides an experimental basis for clinical application of YPF-P. | Yang Hong Deng Hua Lu Yuemei Li Minshen Pu Wenjun | 2015 | Animal Husbandry and Feed Science2015，7，2： | 1 |
| 15 | Prediction of the Spread of Smoke in a Huge Transit Terminal Subway Station Under Six Different Fire Scenarios 显示文摘 | Gao Ran Li Angui Hao Xinpeng Lei Wenjun Deng Baoshun | 2012 | Tunnelling and Underground Space Technology2012，31，1： | 1 |
| 16 | Essential Role of Smad3 in Angiotensin II–Induced Vascular Fibrosis显示文摘 | Wansheng Wang Xiao R. Huang Ellery Canlas Kazuhiro Oka Luan D. Truong Chuxia Deng Neil A. Bhowmick Wenjun Ju Erwin P. Bottinger Hui Y. Lan | 2006 | Circulation Research2006，，8： | 1 |
| 17 | Prediction of the spread of smoke in a huge transit terminal subway station under six different fire scenarios显示文摘 | Ran Gao Angui Li Xinpeng Hao Wenjun Lei Baoshun Deng | 2012 | Tunnelling and Underground Space Technology incorporating Trenchless Technology Research2012，，： | 1 |
| 18 | Solid-phase photocatalytic degradation of polystyrene with modified nano-TiO 2 catalyst显示文摘 | Ling Zan Songlin Wang Wenjun Fa Yanhe Hu Lihong Tian Kejian Deng | 2006 | Polymer2006，，24： | 1 |
| 19 | Breastfeeding, previous Epstein-Barr virus infection, Enterovirus 71 infection, and rural residence are associated with the severity of hand, foot, and mouth disease显示文摘 | Yaping Li Shuangsuo Dang Huiling Deng Wenjun Wang Xiaoli Jia Ning Gao Mei Li Jun Wang | 2013 | European Journal of Pediatrics2013，，5： | 1 |
| 20 | Tumor suppressor p53 functions as an essential antiviral molecule against Japanese encephalitis virus显示文摘Japanese encephalitis virus(JEV)is a mosquito-borne virus of the family Flaviviridae.It is the causative agent of Japanese encephalitis with approximately 50,000 infection cases and 10,000 fatal cases annually in Asia(Erlanger et al.,2009).Although liveattenuated JEV vaccine has been developed and used for human and pig vaccination,JE occurs epidemically or sporadically | Xufang Deng Jianchao Wei Zixue Shi Wenjun Yan Zhuanchang Wu Donghua Shao Beibei Li Ke Liu Xiaodu Wang Yafeng Qiu Zhiyong Ma | 2016 | Journal of Genetics and Genomics2016，43，12： | 1 |
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