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| 1 | Effects of nonalcoholic fatty liver disease on the development of metabolic disorders显示文摘 | Fan, JG Li, F Cai, XB Peng, YD Ao, QH Gao, Y | 2007 | 中国生物学文摘2007，21，11： | 51 |
| 2 | Prevalence of Developmental Dysplasia of the Hip in Chinese Adults: A Cross-sectional Survey显示文摘 | Feng-De Tian De-Wei Zhao Wei Wang Lin Guo Si-Miao Tian Ao Feng Fan Yang Dong-Yi Li | 2017 | Chinese Medical Journal2017，，11： | 18 |
| 3 | Advanced data analytics for enhancing building performances: From data-driven to big data-driven approaches显示文摘Buildings have a significant impact on global sustainability.During the past decades,a wide variety of studies have been conducted throughout the building lifecycle for improving the building performance.Data-driven approach has been widely adopted owing to less detailed building information required and high computational efficiency for online applications.Recent advances in information technologies and data science have enabled convenient access,storage,and analysis of massive on-site measurements,bringing about a new big-data-driven research paradigm.This paper presents a critical review of data-driven methods,particularly those methods based on larger datasets,for building energy modeling and their practical applications for improving building performances.This paper is organized based on the four essential phases of big-data-driven modeling,i.e.,data preprocessing,model development,knowledge post-processing,and practical applications throughout the building lifecycle.Typical data analysis and application methods have been summarized and compared at each stage,based upon which in-depth discussions and future research directions have been presented.This review demonstrates that the insights obtained from big building data can be extremely helpful for enriching the existing knowledge repository regarding building energy modeling.Furthermore,considering the ever-increasing development of smart buildings and IoT-driven smart cities,the big data-driven research paradigm will become an essential supplement to existing scientific research methods in the building sector. | Cheng Fan Da Yan Fu Xiao Ao Li Jingjing An Xuyuan Kang | 2021 | Building Simulation2021，14，1： | 10 |
| 4 | Surface modification of small intestine submucosa in tissue engineering显示文摘With the development of tissue engineering,the required biomaterials need to have the ability to promote cell adhesion and proliferation in vitro and in vivo.Especially,surface modification of the scaffold material has a great influence on biocompatibility and functionality of materials.The small intestine submucosa(SIS)is an extracellular matrix isolated from the submucosal layer of porcine jejunum,which has good tissue mechanical properties and regenerative activity,and is suitable for cell adhesion,proliferation and differentiation.In recent years,SIS is widely used in different areas of tissue reconstruction,such as blood vessels,bone,cartilage,bladder and ureter,etc.This paper discusses the main methods for surface modification of SIS to improve and optimize the performance of SIS bioscaffolds,including functional group bonding,protein adsorption,mineral coating,topography and formatting modification and drug combination.In addition,the reasonable combination of these methods also offers great improvement on SIS surface modification.This article makes a shallow review of the surface modification of SIS and its application in tissue engineering. | Pan Zhao Xiang Li Qin Fang Fanglin Wang Qiang Ao Xiaohong Wang Xiaohong Tian Hao Tong Shuling Bai Jun Fan | 2020 | Regenerative Biomaterials2020，7，4： | 9 |
| 5 | ANALYSIS OF COLUMN-INTEGRATED AEROSOL OPTICAL THICKNESS IN BEIJING FROM AERONET OBSERVATIONS显示文摘Aerosol Optical Thickness (AOT), water vapor content and derived Angstrom exponent acquired by a CIMEL sun photometer in Beijing are analyzed. Monthly means computed from quality-assured daily means, seasonal trends and inter-annual variations are presented and discussed. Summer has the highest seasonal average AOT at 440 nm (τa440), Angstrom exponent (α440–870) and water vapor content with the values 0.93, 1.34 and 3.0 cm, respectively. The second highest seasonal average τa440 appears in spring with the largest variation of α440–870 and minimum α440–870 0.99 due to the impact of coarse particles. The minimum seasonal average τa440 (0.44) and water vapor content (0.4 cm) appear in winter. The annual average τa440, α440–870 and water vapor content for about 4-year observation period are 0.70, 1.19 and 1.4 cm, respectively. All monthly average Angstrom exponents are within 0.8-1.4, which indicates aerosol in Beijing is a very complex mixture of both fine- and coarse-mode particles (from anthropogenic influence and natural mineral dust). | Xuehua Fan Hongbin Chen Philippe Goloub Xiang'ao Xia Wenxing Zhang Bernadette Chatenet | 2006 | China Particuology2006，4，6： | 9 |
| 6 | AI_4C_3 Hydration Thermochemical Analysis for Burned Carbon-containing Refractories with Al显示文摘In this paper, X-ray diffractogram analysis and SEM observation of Al4 C3 formed at high temperature from carbon-containing refractories with Al have been carried out.Aluminum added to carbon-containing refractories reacts with C(s)to form Al4 C3(s) gradually during heating from 600 ℃ to 1200℃.It is considered that the interlocked structure of Al4 C3 plate crystals promotes the outstanding increase of hot modulus of rupture of carbon-containing refractories with Al. The HMOR of carbon-containing refractories added with Al additive from 0 to 5wt% increases by 2.8 times being from 6.5MPa to 18.2MPa.After a thermochemical calculation for hydration reaction processes of Al4 C3 and H2O(g), the equilibrium partial pressure chart of H2O(g)in H2O-Al4C3-Al(OH)3 system vs various temperatures has been attained . The H2O (g) partial pressure in the air needed for the Al4 C3 hydration reaction is no more than 10~18 atm at the temperature below 120℃.It is considered that the burned carbon-containing refractories with Al is extremely easy to hydrate and the cracking of burned carbon-containing refractories is generated because that the hydration expansion is 2.11 times during transforming from Al4 C3 to Al(OH)3.The fundamental measure against hydration of the refractories is to insulate the refractories from H2O(g)by various means such as pitch impregnation or other sealing materials. | YANG Ding’ao, YU Zhiming and FAN Liuwu( Sanmenxia Polytechnic College, Sanmenxia, Henan 472000, China ) | 2003 | China's Refractories2003，12，1： | 5 |
| 7 | High-order mode lasing in all-FMF laser cavities显示文摘We experimentally demonstrate two kinds of all few-mode fiber(FMF) ring lasers with high-order mode(HOM)oscillation in the laser cavity. One kind is a switchable-wavelength all-FMF HOM laser with an output of tunable optical vortex beams(OVBs); the other is a Q-switched all-FMF HOM laser with an output of pulsed cylindrical vector beams(CVBs). The lasers are composed of all-FMF components and few-mode erbium-doped fiber. A Sagnac interferometer made of a 3 dB FMF coupler functions as the wavelength selector, and switchable multiwavelength tunable OVBs are experimentally realized. Carbon nanotube-based saturable absorbers and the nonlinear polarization rotation technique are used to achieve Q-switched CVB lasers. This is the first report, to our knowledge, on the generation of switchable-wavelength and Q-switched HOM beams in all-FMF laser cavities. | TENG WANG AO YANG FAN SHI YIPING HUANG JIANXIANG WEN XIANGLONG ZENG | 2019 | Photonics Research2019，7，1： | 4 |
| 8 | lonization and dissociation of acetonitrile by intense femtosecond laser pulse显示文摘Photoionization and photodissociation of CH3CN were studied by a linear time of flight mass spectrometer coupled with 800 nm, 50 fs laser pulses at intensities of 6.3×1013-1.2×1014 W/cm2. The laser power dependences for principal ions CH3CN+, CH2CN+, CHCN+ and CCN+ were measured, which are consistent with the numbers of photons required to produce the ions via multiphoton ionization and dissociation. The results show that eight-photon non-resonant multiphoton ionization is the main photoionization mechanism of the parent ion CH3CN+, while the fragment ions were produced through the dissociation of the molecules in the super-excited states. | WU Chengyin, XIONG Yijia, GAO Zhen, KONG Fan’ao, LU Haihe, YANG Xiaodong & XU ZhizhanInstitute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China Correspondence should be addressed to Kong Fan’ao | 2000 | Chinese Science Bulletin2000，45，21： | 3 |
| 9 | Ag@Au core/shell triangular nanoplates with dual enzyme-like properties for the colorimetric sensing of glucose显示文摘Due to the serious harm of diabetes to human health,development of sensitive assays for glucose level is of high significance for early prevention and treatment of diabetes.Currently,most conventional enzyme-based glucose sensors suffer from high cost and low stability due to the inherent defects of natural enzymes.Herein,we develop a pure nanozyme-based glucose detection method using Ag@Au core/shell triangular nanoplates(TNPs),which combines glucose oxidase(GOD)-and horseradish peroxidase(HRP)-like activities of the Au shell and inherent plasmonic properties of Ag TNPs.The sensing mechanism is based on the fact that the Au shell possessed GOD-like activity,enabling the oxidation of glucose to produce H2O2,which can further etch the silver core,leading to the decrease of absorbance at 800 nm and the color change from blue to colorless.Compared with the previous nanozymes-based glucose sensors,our method avoids the use of enzymes and organic chromogenic agent.Moreover,the stability of the Ag@Au core/shell TNPs is much better than that of Ag TNPs due to the protection by the coating of the Au shell.This method was successfully applied to the detection of urine samples from patients with diabetes,indicating its practical applicability for real sample analysis. | Ao Liu Mengmeng Li Jingxiang Wang Fan Feng Yu Zhang Zhiwei Qiu Yuzhu Chen Benjamin Edem Meteku Congying Wen Zifeng Yan Jingbin Zeng | 2020 | Chinese Chemical Letters2020，31，5： | 3 |
| 10 | Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model显示文摘 | Wei-wei GU Gui-zhen AO Yong-ming ZHU Shi-chang SUN Qiang ZHOU Jia-hong FAN Katunuma NOBUHIKO Kazumi ISHIDOH Hui-ling ZHANG Xiu-mei GAO | 2013 | Acta Pharmacologica Sinica2013，34，8： | 3 |
| 11 | Development of an ANN-based building energy model for information-poor buildings using transfer learning显示文摘Accurate building energy prediction is vital to develop optimal control strategies to enhance building energy efficiency and energy flexibility.In recent years,the data-driven approach based on machine learning algorithms has been widely adopted for building energy prediction due to the availability of massive data in building automation systems(BASs),which automatically collect and store real-time building operational data.For new buildings and most existing buildings without installing advanced BASs,there is a lack of sufficient data to train data-driven predictive models.Transfer learning is a promising method to develop accurate and reliable data-driven building energy prediction models with limited training data by taking advantage of the rich data/knowledge obtained from other buildings.Few studies focused on the influences of source building datasets,pre-training data volume,and training data volume on the performance of the transfer learning method.The present study aims to develop a transfer learning-based ANN model for one-hour ahead building energy prediction to fill this research gap.Around 400 non-residential buildings’data from the open-source Building Genome Project are used to test the proposed method.Extensive analysis demonstrates that transfer learning can effectively improve the accuracy of BPNN-based building energy models for information-poor buildings with very limited training data.The most influential building features which influence the effectiveness of transfer learning are found to be building usage and industry.The research outcomes can provide guidance for implementation of transfer learning,especially in selecting appropriate source buildings and datasets for developing accurate building energy prediction models. | Ao Li Fu Xiao Cheng Fan Maomao Hu | 2021 | Building Simulation2021，14，1： | 3 |
| 12 | Intensive Radiosonde Measurements of Summertime Convection over the Inner Mongolia Grassland in 2014:Difference between Shallow Cumulus and Other Conditions显示文摘Using radiosonde measurements from 26 July to 30 July 2014 at Baiqi over the Inner Mongolia grassland of China, the vertical structure of shallow cumulus(SCu) clouds and associated environmental conditions were investigated. The cloud base height and the cloud top height of SCu was 3.4 km and 5 km, respectively. The temperature of the SCu layer was less than 0℃. The horizontal advection of specific humidity was smaller than the vertical transport in the atmosphere below 5 km.Above 5 km, the thermodynamic structure of the atmosphere remained stable. At the interface of the cloud layer and free air atmosphere, there was obvious wind shear and a temperature inversion(~2.9℃). Comparisons of environmental parameters associated with cumulus congestus, rain and clear days, showed that the formation of SCu was characterized by a higher Bowen ratio(high sensible heat flux and low latent heat flux), which indicated intensive turbulence in the boundary layer. The formation of SCu was associated with the boundary layer height exceeding the lifting condensation level. The maintenance of SCu was likely associated with the lower convective available potential energy, weak wind shear, and weak subsidence of the synoptic system, which did not favor the dramatic vertical development of SCu and thereby the transformation of SCu to cumulus congestus. | Hongrong SHI Hongbin CHEN Xiang'ao XIA Xuehua FAN Jinqiang ZHANG Jun LI Chao LING | 2017 | Advances in Atmospheric Sciences2017，34，6： | 2 |
| 13 | Medical Additive Manufacturing: From a Frontier Technology to the Research and Development of Products显示文摘1.Research and development(R&D)and the challenges of raw materials for medical additive manufacturing Raw materials for medical additive manufacturing have a wide range of commonalities that are also seen in many other fields,making them an important basis in the field of three-dimensional(3D)printing.Problems and challenges related to material types,powder properties,formability,viscoelasticity,and so forth also share common features.For example,many metal materials are used in the field of aviation,while metals,polymers,and inorganic materials are used in the field of biomedicine.The most widely used materials in biomedicine are biocompatible.Various homogeneous and non-homogeneous composites are also available for 3D printing,and impose an additional challenge in additive manufacturing;the use of heterogeneous composites in 3D printing is particularly challenging. | Guixing Qiu Wenjiang Ding Wei Tian Ling Qin Yu Zhao Lianmeng Zhang Jian Lu Daijie Chen Guangyi Yuan Chengtie Wu Bingheng Lu Ruxu Du Jimin Chen Mo Elbestawi Zhongwei Gu Dichen Li Wei Sun Yuanjin Zhao Jie He Dadi Jin Bin Liu Kai Zhang Jianmo Li Kam WLeong Dewei Zhao Dingjun Hao Yingfang Ao Xuliang Deng Huilin Yang ShaoKeh Hsu Yingqi Chen Long Li Jianping Fan Guohui Nie Yun Chen Hui Zeng Wei Chen Yuxiao Lai | 2020 | Engineering2020，6，11： | 1 |
| 14 | An integrative analysis of four CESA isoforms specific for fiber cellulose production between Gossypium hirsutum and Gossypium barbadense显示文摘 | Ao Li Tao Xia Wen Xu Tingting Chen Xianliang Li Jian Fan Ruyi Wang Shengqiu Feng Yanting Wang Bingrui Wang Liangcai Peng | 2013 | Planta2013，，6： | 1 |
| 15 | Supported Lal_xCexMn03 perovskite catalysts: preparation, characterization and catalytic performance in methane combustion显示文摘 | Ying SHAO Xiao-Fei WANG Min AO Cai-Rong GONG Guo-Liang FAN Hai-Feng CHEN | 2012 | Frontiers of Materials Science2012，6，4： | 1 |
| 16 | Fabricating pyridinic N-B sites in porous carbon as efficient metal-free electrocatalyst in conversion CO_(2)into CH_(4)显示文摘Electrochemical reduction of CO_(2)(CO_(2)RR)to value-added chemicals is an attractive strategy for greenhouse gas mitigation and carbon recycle.Carbon material is one of most promising electrocatalysts but its product selectivity is limited by few modulating approaches for active sites.Herein,the predominant pyridinic N-B sites(accounting for 80%to all N species)are fabricated in hierarchically porous structure of graphene nanoribbons/amorphous carbon.The graphene nanoribbons and porous structure can accelerate electron and ion/gas transport during CO_(2)RR,respectively.This carbon electrocatalyst exhibits excellent selectivity toward CO_(2)reduction to CH_(4)with the faradaic efficiency of 68%at−0.50 V vs.RHE.As demonstrated by density functional theory,a proper adsorbed energy of∗CO and∗CH_(2)O are generated on the pyridinic N-B site resulting into high CH_(4)selectivity.Therefore,this study provides a novel method to modulate active sites of carbon-based electrocatalyst to obtain high CH_(4)selectivity. | Yuying Zhao Qixin Yuan Mengmeng Fan Ao Wang Kang Sun Zeming Wang Jianchun Jiang | 2023 | Chinese Chemical Letters2023，34，8： | 1 |
| 17 | An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk,local immunosuppression and tumor progression显示文摘Dissecting and understanding the cancer ecosystem,especially that around the tumor margins,which have strong implications for tumor cell infiltration and invasion,are essential for exploring the mechanisms of tumor metastasis and developing effective new treatments.Using a novel tumor border scanning and digitization model enabled by nanoscale resolution-SpaTial Enhanced REsolution Omics-sequencing(Stereo-seq),we identified a 500µm-wide zone centered around the tumor border in patients with liver cancer,referred to as“the invasive zone”.We detected strong immunosuppression,metabolic reprogramming,and severely damaged hepatocytes in this zone.We also identified a subpopulation of damaged hepatocytes with increased expression of serum amyloid A1 and A2(referred to collectively as SAAs)located close to the border on the paratumor side.Overexpression of CXCL6 in adjacent malignant cells could induce activation of the JAK-STAT3 pathway in nearby hepatocytes,which subsequently caused SAAs’overexpression in these hepatocytes.Furthermore,overexpression and secretion of SAAs by hepatocytes in the invasive zone could lead to the recruitment of macrophages and M2 polarization,further promoting local immunosuppression,potentially resulting in tumor progression.Clinical association analysis in additional five independent cohorts of patients with primary and secondary liver cancer(n=423)showed that patients with overexpression of SAAs in the invasive zone had a worse prognosis.Further in vivo experiments using mouse liver tumor models in situ confirmed that the knockdown of genes encoding SAAs in hepatocytes decreased macrophage accumulation around the tumor border and delayed tumor growth.The identification and characterization of a novel invasive zone in human cancer patients not only add an important layer of understanding regarding the mechanisms of tumor invasion and metastasis,but may also pave the way for developing novel therapeutic strategies for advanced liver cancer and other solid tumors. | Liang Wu Jiayan Yan Yinqi Bai Feiyu Chen Xuanxuan Zou Jiangshan Xu Ao Huang Liangzhen Hou Yu Zhong Zehua Jing Qichao Yu Xiaorui Zhou Zhifeng Jiang Chunqing Wang Mengnan Cheng Yuan Ji Yingyong Hou Rongkui Luo Qinqin Li Liang Wu Jianwen Cheng Pengxiang Wang Dezhen Guo Waidong Huang Junjie Lei Shang Liu Yizhen Yan Yiling Chen Sha Liao Yuxiang Li Haixiang Sun Na Yao Xiangyu Zhang Shiyu Zhang Xi Chen Yang Yu Yao Li Fengming Liu Zheng Wang Shaolai Zhou Huanming Yang Shuang Yang Xun Xu Longqi Liu Qiang Gao Zhaoyou Tang Xiangdong Wang Jian Wang Jia Fan Shiping Liu Xinrong Yang Ao Chen Jian Zhou | 2023 | Cell Research2023，33，8： | 1 |
| 18 | Dissociation of methanol in intense femtosecond laser field显示文摘Methanol was irradiated by 80 fs laser pulse, intensity range of 1013-1014 W/cm2. A TOF-mass spectrometer was coupled to the laser system and used to detect the ions produced. The parent ions CH3OH+ appeared firstly at the laser intensity of 1.4 ×1013 W/cm2. While the laser intensity was gradually increased, the parent ions were dissociated and the primary ions CH2OH+ were given as verified from the irradiation of deuterated methanol (CH3OD) showing the C-H bond cracking firstly. While the laser intensity was further increased to 2.0 ×1013 W/cm2, the C-O bonds of the parent ions also broke to give CH3+. When the laser intensity was higher, smaller fragment ions like CH+, C+, OH+ and O+ also appeared. Among the fragment ions, only H+ ion yield had anisotropic angular distribution dependence on the laser polarization vector in the dissociation of methanol. All the experimental observations show that the dissociation of methanol proceeds through stepwise mechanism but not Coulomb explosion. | Xiaoping Tang Lirong Gao Yonglin Wang Cao Wang Sufan Wang Fan’ao Kong | 2002 | Chinese Science Bulletin2002，47，23： | 1 |
| 19 | The asymmetry of the upper and the lower visual-field in spatial selective attention: an high resolution ERP study显示文摘 | Ao XY Fan SL He X et ol | 2000 | Neuro Image2000，11，5： | 1 |
| 20 | Involvement of antioxidant defense sys- tem in chill hardening- induced chilling tolerance in Jatropha curcas seedlings 显示文摘 | AO P X LI Z G FAN D M | 2013 | Acta Physiol Plant2013，35，1： | 1 |
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