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| 1 | Effect of catgut implantation at acupoints on GABA_B and mGluR1 expressions in brain stem of rats with spasticity after stroke显示文摘OBJECTIVE: To investigate the effect of catgut implantation at acupoints on the expressions of γ-amino butyric acid B receptor(GABAB ) and metabotropic glutamate receptor 1(mGluR1) in the brain stem of rats with spasticity after stroke.METHODS: In total, 60 male Sprague-Dawley rats were randomly divided into three groups: a sham group(n=10), a model group(n=25) and a treatment group(n=25). The rats in both the model group and the treatment group were subjected to middle cerebral artery occlusion to establish a model of focal cerebral ischemia. Rats with limb-spasm met the inclusion criteria. Only the left carotid artery was isolated in sham group rats. Three days after modeling, the treatment group was subjected to catgut implantation at Dazhui(GV 14), Guanyuan(CV 4), and Zhongwan(CV 12). Neurological deficit symptoms were assessed with the Zea-Longa neurological deficit score. The Modified Ashworth Scale(MAS), and isolated muscle tone were used to evaluate spasticity before and after treatment. Immunohistochemistry was applied to determine the expression of GABAB and mGluR1 in the rat brain stem after treatment.RESULTS: After treatment, neural impairment symptoms had significantly improved in the treatment group when compared to the model group(P<0.05). Both MAS and isolated muscle tone in the treatment group were significantly decreased when compared with the model group(P<0.05),and were also lower than before treatment. GABAB expression was significantly higher and mGluR1 was lower in the treatment group when compared with the model group(P<0.01 and P<0.05, respectively).CONCLUSION: Catgut implantation at Dazhui(GV 14), Guanyuan(CV 4), and Zhongwan(CV 12), can relieve limb spasticity by increasing the expression of GABAB and reducing the expression of mGluR1 in the brain stem of rats after stroke. | Chengmei Liu Ruiqing Li Xiaolei Song Xiaodong Feng | 2014 | Journal of Traditional Chinese Medicine2014，34，5： | 14 |
| 2 | Microstructural investigation of Nd-rich phase in sintered Nd-Fe-B magnets through electron microscopy显示文摘intergranular 的分发,形态学和结构在 sintered Nd-Fe-B 磁铁的 Nd 富有的阶段通过电子显微镜学被学习。Backscattered 电子(BSE ) 成像表明有各种各样的形态学和尺寸的 Nd 富有的粒子在谷物边界和四角形的 Nd2Fe14B 矩阵的三倍的连接是随机分布式的。通过选择区域电子衍射(SAED ) 在一个系统的倾斜条件下面的分析,大多数 intergranular 与从几百 nanometres 到几 micrometres 的尺寸, Nd 富有的阶段粒子作为集中脸被识别立方(FCC ) 结构。如此的粒子与他们的邻近的 Nd2Fe14B 矩阵谷物拥有了几种近似取向关系,例如(002 )Nd2Fe14B//(200 )FCC_Nd 富有[120 ]Nd2Fe14B//[001 ]FCC_Nd 富有,(002 )Nd2Fe14B//(22 ? 湯洠条敮楴慺楴湯爠癥牥慳? 敢慨楶牯映牯愠湮慥敬 ? 摎 ???? 敆渠湡潣灭獯瑩 ? | FU Xin HAN Xiaolei DU Zhiwei FENG Haibo LI Yanfeng | 2013 | Journal of Rare Earths2013，31，8： | 11 |
| 3 | Altered regional homogeneity in post-traumatic stress disorder: a resting-state functional magnetic resonance imaging study显示文摘Objective Little is known about the brain systems that contribute to vulnerability to post-traumatic stress disorder (PTSD). Comparison of the resting-state patterns of intrinsic functional synchronization, as measured by functional magnetic resonance imaging (fMRI), between groups with and without PTSD following a traumatic event can help identify the neural mechanisms of the disorder and targets for intervention. Methods Fifty-four PTSD patients and 72 matched traumatized subjects who experienced the 2008 Sichuan earthquake were imaged with blood oxygen level-dependent (BOLD) fMRI and analyzed using the measure of regional homogeneity (ReHo) during the resting state. Results PTSD patients presented enhanced ReHo in the left inferior parietal lobule and right superior frontal gyrus, and reduced ReHo in the right middle temporal gyrus and lingual gyrus, relative to traumatized individuals without PTSD. Conclusion Our findings showed that abnormal brain activity exists under resting conditions in PTSD patients who had been exposed to a major earthquake. Alterations in the local functional connectivity of cortical regions are likely to contribute to the neural mechanisms underlying PTSD. | Yan Yin Changfeng Jin Lisa T. Eyler Hua Jin Xiaolei Hu Lian Duan Huirong Zheng Bo Feng Xuanyin Huang Baoci Shan Qiyong Gong Lingjiang Li | 2012 | Neuroscience Bulletin2012，28，5： | 9 |
| 4 | Effect of nitrogen on corrosion behaviour of a novel high nitrogen medium-entropy alloy CrCoNiN manufactured by pressurized metallurgy显示文摘A novel high nitrogen medium-entropy alloy CrCoNiN, which had higher strength and slightly lower ductility than CrCoNi alloy, was successfully manufactured by pressurized metallurgy. The microstructure and corrosion behaviour were investigated by microscopic, electrochemical and spectroscopic methods.The results indicated that nitrogen existed in the form of Cr_2N precipitates and uniformly distributed N atoms, and nitrogen alloying significantly refined the grain size. Besides, nitrogen enriched on the outmost surface of passive film and metal/film interface as ammonia(NH-_3 and NH_4^+) and CrN, respectively. The significant improvement of corrosion resistance of CrCoNiN was attributed to the lower metastable pitting susceptibility together with thicker, less defective and more compact passive film. | Hao Feng Huabing Li Xiaolei Wu Zhouhua Jiang Si Zhao Tao Zhang Dake Xu Shucai Zhang Hongchun Zhu Binbin Zhang Muxin Yang | 2018 | Journal of Materials Science & Technology2018，34，10： | 8 |
| 5 | Trot Gait Design and CPG Method for a Quadruped Robot显示文摘 | Jiaqi Zhang Feng Gao Xiaolei Han Xianbao Chen Xueying Han | 2014 | Journal of Bionic Engineering2014，11，1： | 7 |
| 6 | Detection of radio-frequency interference signals from AMSR-E data over the United States with snow cover显示文摘收音机频率干扰(射频干扰) 引起严重污染到察觉到观察和相应检索产品的被动、活跃的微波。射频干扰信号应该在把微波数据用于检索和数据吸收前被检测并且过滤。在因为雪表面的散布效果,雪盖住的陆地表面上检测射频干扰是困难的。双主要部件分析(DPCA ) 方法在这研究被采用,并且它在识别射频干扰的能力在雪上在 AMSR-E 数据发信号盖住的区域被调查。结果证明尽管有散布的雪的影响, DPCA 方法能有效地检测射频干扰信号,并且检测射频干扰发信号坚持随着时间的过去。比作另外的方法,例如 PCA 并且使 PCA 正常化, DPCA 为运作的申请更柔韧、合适。 | Chengcheng FENG Xiaolei ZOU Juan ZHAO | 2016 | Frontiers of Earth Science2016，10，2： | 5 |
| 7 | Improvement of the assimilable organic carbon (AOC) analytical method for reclaimed water显示文摘 | Xin ZHAO Hongying HU Shuming LIU Feng JIANG Xiaolei SHI Mingtang LI Xueqiao XU | 2013 | Frontiers of Environmental Science & Engineering2013，7，4： | 5 |
| 8 | Mammography combined with breast dynamic contrast-enhanced-magnetic resonance imaging for the diagnosis of early breast cancer显示文摘Objective The aim of this study was to investigate the application of mammography combined with breast dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) for the diagnosis of early breast cancer. Methods Mammography and DCE-MRI were performed for 120 patients with breast cancer(malignant, 102; benign; 18). Results The sensitivity of mammography for early diagnosis of breast cancer was 66.67%, specificity was 77.78%, and accuracy was 68.33%. The sensitivity of MRI for early diagnosis of breast cancer was 94.12%, specificity was 88.89%, and accuracy was 93.33%. However, the sensitivity of mammography combined with DCE-MRI volume imaging with enhanced water signal(VIEWS) scanning for early diagnosis of breast cancer was 97.06%, specificity was 94.44%, and accuracy was 96.67%. Conclusion Mammography combined with DCE-MRI increased the sensitivity, specificity, and accuracy of diagnosing early breast cancer. | Yakun He Guohui Xu Jin Ren Bin Feng Xiaolei Dong Hao Lu Changjiu He | 2016 | Oncology and Translational Medicine2016，2，4： | 4 |
| 9 | Factors Controlling Hydrocarbon Accumulation in Jurassic Reservoirs in the Southwest Ordos Basin, NW China显示文摘The sedimentary, paleogeomorphological and reservoir characteristics of the Jurassic Yan’an Formation in the southwestern Ordos Basin, northwestern China, were studied by means of casting thin sections, scanning electron microscopy, inclusion analysis and identification of low-amplitude structures. A model for reservoir formation is established, and the controlling effects of sedimentary facies, paleotopography, low-amplitude structures and formation water on oil reservoirs are revealed. There are significant differences in the sedimentary characteristics, structural morphology and paleowater characteristics between the reservoirs above the Yan 10 Member and those in the Yan 9 to Yan 7 Members. The Yan 10 Member contains fluvial sediments, whereas the Yan 9 to Yan 7 members contain delta-plain anastomosing-river deposits. The distribution of high-permeability reservoir is controlled by pre-Jurassic paleogeomorphology and sedimentary facies. Some of these facies exhibit high porosity and high permeability in a lowpermeability background. The main hydrocarbon accumulation period was the late Early Cretaceous, filling was continuous, and the charging strength altered from weak to strong and then from strong to weak. The Yan 10 reservoir is mainly controlled by the paleogeomorphology: hydrocarbons migrated upward at a high speed through the unconformity surface, and accumulated in the favorable traps formed by paleogeomorphic structural units, such as gentle slopes or channel island. Furthermore, groundwater alternation in these areas was relatively stagnant, providing good reservoir preservation conditions. The reservoirs in the Yan 9 and higher members are controlled by the sedimentary facies, lowamplitude structure and paleowater characteristics. Hydrocarbons migrated through the three-dimensional delivery system, influenced by favorable sedimentary facies and high-salinity groundwater, then accumulated in the favorable low-amplitude structural traps that formed during the hydrocarbon production period. | LIU Xin WANG Feng LIU Baojun TIAN Jingchun SHANG Ting MA Jiong ZHANG Zhongyi ZHANG Xiaolei | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 4 |
| 10 | Nutrient Composition of Different Foxtail Millet Seeds显示文摘Ten millet cultivars from China and abroad were analyzed for their crude fat,amylose and amylopectin,crude protein and amino acid content. A wide variation was observed in amylopectin contain,ranging from 54. 47% to 69. 26%,while amylose content ranged from 11. 26% to 23. 22%. The average crude fat in all cultivates was 3. 46%,and most cultivates ranged from 3. 1% to 3. 7%. Protein contents ranged from 8. 61% to 15. 54% with a mean value of 11. 94%. For amino acid composition,the ten cultivates were particularly rich in leucine,and the mean was 34. 57 mg/g. The millet cultivars were also high in glycine,glutamic acid and cysteine. Millet was known to be limiting in the essential amino lysine,and the mean was 5. 18 mg/g. Other amino acids,tyrosine,histidine and arginine were also very low in the ten cultivars. In general,significant nutrient composition differences were observed between the different millet cultivars,and A2( a kind of mother line of the hybrid millet) and hybrid millet registered a higher level of protein and amino acid composition which would be useful in millet breeding. | Guangyu FAN Jincheng YUAN Lina ZHANG Xiaojie LIU Xiaoming WANG Feng WANG Xiaolei FENG Guoliang SONG Haiying ZHANG Qian WANG Zhihai ZHAO Yinghui LIU | 2018 | Agricultural Biotechnology2018，7，5： | 4 |
| 11 | Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation显示文摘Accumulating evidence suggests that a reduction in the number of Foxp3^(+) regulatory T cells(Tregs)contributes to the pathogenesis of acute graft-versus-host disease(aGVHD),which is a major adverse complication that can occur after allogeneic hematopoietic stem cell transplantation(allo-HSCT).However,the precise features and mechanism underlying the defects in Tregs remain largely unknown.In this study,we demonstrated that Tregs were more dramatically decreased in bone marrow compared with those in peripheral blood from aGVHD patients and that bone marrow Treg defects were negatively associated with hematopoietic reconstitution.Tregs from aGVHD patients exhibited multiple defects,including the instability of Foxp3 expression,especially in response to IL-12,impaired suppressor function,decreased migratory capacity,and increased apoptosis.Transcriptional profiling revealed the downregulation of Lkb1,a previously identified critical regulator of murine Treg identity and metabolism,and murine Lkb1-regulated genes in Tregs from aGVHD patients.Foxp3 expression in human Tregs could be decreased and increased by the knockdown and overexpression of the Lkb1 gene,respectively.Furthermore,a loss-of-function assay in an aGVHD murine model confirmed that Lkb1 deficiency could impair Tregs and aggravate disease severity.These findings reveal that Lkb1 downregulation contributes to multiple defects in Tregs in human aGVHD and highlight the Lkb1-related pathways that could serve as therapeutic targets that may potentially be manipulated to mitigate aGVHD. | Xiuhua Su Qianqian Wang Wei Guo Xiaolei Pei Qing Niu Maolan Liu Yuanyuan Liu Song Chen Sizhou Feng Yi He Donglin Yang Rongli Zhang Qiaoling Ma Weihua Zhai Aiming Pang Jialin Wei Yong Huang Yuechen Luo Mingzhe Han Xiaoming Feng Erlie Jiang | 2020 | Cellular & Molecular Immunology2020，17，5： | 3 |
| 12 | CeO_(2)with diverse morphologies-supported IrOx nanocatalysts for efficient oxygen evolution reaction—Commemorating the 100th anniversary of the birth of Academician Guangxian Xu显示文摘IrOx-based catalysts are considered the most promising candidates for oxygen evolution reaction(OER)due to their high efficiency.However,improving their intrinsic catalytic activity is essential for practical application.In this work,CeO_(2)with three different morphologies(rod,cube,octahedron)and supported IrOx nanoparticles were fabricated,and they display morphology-dependent OER activity.The IrOx/CeO_(2)-rod shows the highest activity;the catalysts have a catalytic activity sequence of rod>cube>octahedron.A plausible mechanism was proposed:the CeO_(2)support with different morphologies modulates the electronic structure of IrOx by the synergistic interaction promoted by oxygen vacancies between the active component and the support,thereby altering the catalytic activity of the IrOx/CeO_(2)catalyst. | Qingqing Li Zhichao Zeng Xiaolei Sun Feng Luo Yaping Du | 2021 | Journal of Rare Earths2021，39，4： | 3 |
| 13 | Interaction Between Tangeretin and Ovalbumin to Reduce the Allergic Effects of Ovalbumin显示文摘 | SHI Xiaolei ZHANG Ting LI Xuwen FENG Yu TAN Xin JIN Yongri | 2016 | Chemical Research in Chinese Universities2016，32，4： | 2 |
| 14 | Analysis of Quenching Stresses in 35CrMo Axle显示文摘By using the finite element method(FEM), we comprehensively analyzed the fields of temperature, organization, and stress in 35CrMo train axles during the quenching process is conducted, and experimentally studied the formation and evolution of inner stresses in axles during the quenching process. The results show that in the quenching process, stresses on the axle surface change from tensile to compressive gradually, while stresses in the axle core change from compressive to tensile gradually. Heat stresses and the amount of martensitic transformation are all increased with the increase of cooling rate. As a result, the maximum instantaneous stresses in the axle are increased greatly when the cooling rate is increased with brine quenching. Large instantaneous tensile stress in the axle core with brine quenching is very likely to cause quench cracking and should be avoided. | 龚海 WU Yunxin FENG Xiaolei LI Yihua | 2016 | Journal of Wuhan University of Technology(Materials Science)2016，31，3： | 2 |
| 15 | A near-infrared optical tomography system based on photomuhiplier tube 显示文摘 | Feng Huacheng Bai Jing Song Xiaolei | 2007 | Int J Biomed Imaging2007，6，28： | 1 |
| 16 | Seed traits and rodent community interact to determine seed fate:evidence from both enclosure and field experiments显示文摘Animal-mediated seed dispersal is an important ecological process in which a strong mutualism between animals and plants can arise.However,few studies have examined how a community of potential seed dispersers interacts with sympatric seed trees.We employed a series of experiments in the Qinling Mountains in both semi-natural enclosure and the field to assess the interactions among 3 sympatric rodent species and 3 Fagaceae tree seeds.Seed traits all showed similar tannin levels but markedly different physical traits and nutritional contents.We found that seeds with heavy weight,thick coat,and high nutritional contents were less likely to be eaten in situ but more often to be eaten after dispersal or hoarded by rodents.These results support both the handling time hypothesis and the high nutrition hypothesis.Surprisingly,we also found that rodents,maybe,preferred to consume seeds with low levels of crude fiber in situ,and to harvest and hoard those with high levels of crude fiber for later consumption.The sympatric rodent species,Cansumys canus,the largest rodent in our study,harvested and hoarded more Quercus variabilis seeds with high physical and nutritional traits,while Apodemus draco,the smallest rodent,harvested more Q.serrata seeds with low physical and nutritional traits,and Niviventer confucianus harvested and hoarded more Q.aliena seeds with medium physical and nutritional traits.Our study demonstrates that different seed traits play different roles in influencing the seed fate and the shaping of mutualism and predation interactions within a community of rodent species. | Xiang HOU Bo ZHANG Michael A.STEELE Ning HAN Tuo FENG Jing WANG Xiaoning CHEN Xiaolei AN Gang CHANG | 2021 | Integrative Zoology2021，16，6： | 1 |
| 17 | Air bearing center cross gap of neutron stress spectrometersample table support system显示文摘A support system is the main load-beatingcomponent of sample table for neutron stress spectrometer,and air beating is an important element of a supportsystem. The neutron stress spectrometer sample table wasintroduced, and the schemewas selected. To study thefor air beating combinationperformance of air beatingcenter cross gap, finite element models (FEMs) wereestablished based on air motion and Reynolds equations,effects of air supply pressure, and gap parameters on theoverturning moment and beating capacity of air beatingcenter cross gap were analyzed. Results indicate that thewidth, depth, and height differences of the marble floor gapplayed important roles in the performance of the airbearing. When gap width is lesser than 1 mm and gapdepth is lower than 0.4 mm, bearing capacity andoverturning moment would vary rapidly with the variationof the width and depth. A gap height difference results inthe beating capacity dropping rapidly. The FEM resultsagree well with experimental results. Further, findings ofthe study could guide the design of the support system andmarble floor. | Yang LI Yunxin WU Hai GONG Xiaolei FENG | 2016 | Frontiers of Mechanical Engineering2016，11，4： | 1 |
| 18 | Reconstruction of tissue diffusion optical tomography using perturbation method 显示文摘 | Feng Huacheng Bai Jing Song Xiaolei | 2007 | Tsinghua Univ(Sci & Tech)2007，47，12： | 1 |
| 19 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 20 | Sensorless Control of Permanent Magnet Synchronous Motor Based on New Sliding Mode Observer with Single Resistor Current Reconstruction显示文摘To solve the chattering problem caused by discontinuous switching function in traditional sliding mode observer,a piecewise square root switching function with continuously varying characteristics is designed,and its stability is analyzed by using Lyapunov stability criterion.Secondly,according to the relationship among bus current,switching state and phase current,a single bus resistance sampling current reconstruction scheme without current sensors is adopted,which effectively reduces the cost of motor system.Finally,the feasibility and effectiveness of the proposed scheme are verified by simulation. | Qingguo Sun Xiaolei Zhu Feng Niu | 2022 | CES Transactions on Electrical Machines and Systems2022，6，4： | 1 |
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