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| 1 | A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV) infected pneumonia(standard version)显示文摘In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province;and then named '2019 novel coronavirus(2019-nCoV)' by the World Health Organization(WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world’s attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development;we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control(including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV. | Ying-Hui Jin Lin Cai Zhen-Shun Cheng Hong Cheng Tong Deng Yi-Pin Fan Cheng Fang Di Huang Lu-Qi Huang Qiao Huang Yong Han Bo Hu Fen Hu Bing-Hui Li Yi-Rong Li Ke Liang Li-Kai Lin Li-Sha Luo Jing Ma Lin-Lu Ma Zhi-Yong Peng Yun-Bao Pan Zhen-Yu Pan Xue-Qun Ren Hui-Min Sun Ying Wang Yun-Yun Wang Hong Weng Chao-Jie Wei Dong-Fang Wu Jian Xia Yong Xiong Hai-Bo Xu Xiao-Mei Yao Yu-Feng Yuan Tai-Sheng Ye Xiao-Chun Zhang Ying-Wen Zhang Yin-Gao Zhang Hua-Min Zhang Yan Zhao Ming-Juan Zhao Hao Zi Xian-Tao Zeng Yong-Yan Wang Xing-Huan Wang 无 | 2020 | Military Medical Research2020，7，1： | 161 |
| 2 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 3 | 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers显示文摘象 5-methylcytosine (5mC ) 和 5-hydroxymethylcytosine (5hmC ) 那样的 DNA 修正是知道在哺乳动物影响全球基因表示的 epigenetic 标记。在人的染色体,与基因表示的靠近的关联和高化学的稳定性给他们的流行,这些 DNA epigenetic 标记能为癌症用作理想的 biomarkers 诊断。利用一种高度敏感、选择的化学标记技术,我们这里报导在传播没有房间的 DNA ( cfDNA )并且在从最近与 colorectal 诊断的 260 个病人的一个队收集的配对的肿瘤和邻近的纸巾的 genomic DNA ( gDNA )的 5hmC 的染色体宽的介绍,胃,胰腺,从 90 个健康个人的肝或甲状腺癌症和正常纸巾。5hmC 主要在与开的染色质和容许的 histone 修正重合的 transcriptionally 活跃的区域被散布。柔韧的联系癌症的 5hmC 签名在 cfDNA 被识别为特定的癌症类型是特征的。传播 cfDNA 的 5hmC 底 biomarkers colorectal 和胃的癌症是高度预兆的并且比常规 biomarkers 优异并且比得上从织物活体检视的 5hmC biomarkers。因此,这新策略能从血样品的分析为癌症的诊断和预后导致有效、最低限度地侵略的方法的发展。 | Wenshuai Li Xu Zhang Xingyu Lu Lei You Yanqun Song Zhongguang Luo Jun Zhang Ji Nie Wanwei Zheng Diannan Xu Yaping Wang Yuanqiang Dong Shulin Yu Jun Hong Jianping Shi Hankun Hao Fen Luo Luchun Hua Peng Wang Xiaoping Qian Fang Yuan Lianhuan Wei Ming Cui Taiping Zhang Quan Liao Menghua Dai Ziwen Liu Ge Chen Katherine Meckel Sarbani Adhikari Guifang Jia Marc B Bissonnette Xinxiang Zhang Yupei Zhao Wei Zhang Chuan He Jie Liu | 2017 | Cell Research2017，27，10： | 30 |
| 4 | Expression and Function of Zinc-α2-Glycoprotein显示文摘Zinc-α2-glycoprotein(ZAG), encoded by the AZGP1 gene, is a major histocompatibility complex I molecule and a lipid-mobilizing factor. ZAG has been demonstrated to promote lipid metabolism and glucose utilization, and to regulate insulin sensitivity. Apart from adipose tissue, skeletal muscle, liver, and kidney, ZAG also occurs in brain tissue, but its distribution in brain is debatable. Only a few studies have investigated ZAG in the brain. It has been found in the brains of patients with Krabbe disease and epilepsy, and in the cerebrospinal fluid of patients with Alzheimer disease, frontotemporal lobe dementia, and amyotrophic lateral sclerosis. Both ZAG protein and AZGP1 m RNA are decreased in epilepsy patients and animal models, while overexpression of ZAG suppresses seizure and epileptic discharges in animal models of epilepsy, but knowledge of the specific mechanism of ZAG in epilepsy is limited. In this review, we summarize the known roles and molecular mechanisms of ZAG in lipid metabolism and glucose metabolism, and in the regulation of insulin sensitivity, and discuss the possible mechanisms by which it suppresses epilepsy. | Xin Wei Xi Liu Changhong Tan Lijuan Mo Hui Wang Xi Peng Fen Deng Lifen Chen | 2019 | Neuroscience Bulletin2019，35，3： | 14 |
| 5 | NGX6 inhibits AP-1 and Ets-1 expression and down-regulates cyclin D1 in human coloreetal cancer显示文摘Colorectal 癌症(CRC ) 是与病态和死亡的增加的发生被联系的一个普通恶意的肿瘤。鼻咽的联系癌的基因(NGX6 ) 6 是肿瘤转移的新奇候选人 suppressor 基因,它在 CRC 是下面调整的。在现在的学习,我们构造了 colorectal 织物 microarray 在 CRC 纸巾检验 NGX6, phospho-c-Jun N 终端 kinase (p-JNK ) ,和 phospho 细胞外的调整信号的 kinase (津贴) 的表示侧面。而 p-JNK 和津贴的表情在 CRC 纸巾是更高的,我们发现 NGX6 表示在 CRC 纸巾和变形淋巴节点是更低的,比在正常肠的 mucosa。NGX6, p-JNK,和津贴的表情与 colorectal 纸巾的临床的病理学的特征被联系。NGX6 overexpression 禁止了激活和 JNK1 的原子 translocation,它在细胞质导致了 p-JNK 的累积,但是没禁止激活和 ERK1/2 的原子 translocation。NGX6 也禁止了抄写因素 AP-1 (c-jun 和 c-fos ) 和 Ets-1 的表示。另外, NGX6 overexpression 减少了 cyclin D1 并且戏剧性地的表示压制了 cyclin D1 倡导者的 transcriptional 效率。我们建议那 NGX6 表情沉醉于人的 colorectal carcinogenesis 的多步过程。它的 overexpression 能禁止抄写因素的表示 AP-1 和 Ets-1,和下面调整在人的 CRC 的 cyclin D1 倡导者的 transcriptional 活动。 | Ya Peng Hongtao Li Minghua Wu Xiaoyan Wang Songqing Fan Fen Liu Bo Xiang Qin Guo Xueyuan Tang Shourong Shen | 2009 | Acta Biochimica et Biophysica Sinica2009，41，6： | 8 |
| 6 | Methodology development and application of X-ray imaging beamline at SSRF显示文摘This paper introduces some latest developments regarding the X-ray imaging methodology and applications of the X-ray imaging and biomedical application beamline(BL13W1)at Shanghai Synchrotron Radiation Facility in the past 5 years.The photon energy range of the beamline is 8–72.5 keV.Several sets of X-ray imaging detectors with different pixel sizes(0.19–24 lm)are used to realize X-ray microcomputed tomography(X-ray micro-CT)and X-ray in-line phase-contrast imaging.To satisfy the requirements of user experiments,new X-ray imaging methods and image processing techniques are developed.In vivo dynamic micro-CT experiments with living insects are performed in 0.5 s(sampling rate of 2 Hz,2 tomograms/s)with a monochromatic beam from a wiggler source and in 40 ms(sampling rate of 25 Hz,25 tomograms/s)with a white beam from a bending magnet source.A new X-ray imaging method known as move contrast X-ray imaging is proposed,with which blood flow and moving tissues in raw images can be distinguished according to their moving frequencies in the time domain.Furthermore,X-ray speckle-tracking imaging with twice exposures to eliminate the edge enhancement effect is developed.A high-precision quantification method is realized to measure complex three-dimensional blood vessels obtained via X-ray micro-CT.X-ray imaging methods such as three-dimensional X-ray diffraction microscopy,small-angle X-ray scattering CT,and X-ray fluorescence CT are developed,in which the X-ray micro-CT imaging method is combined with other contrast mechanisms such as diffraction,scattering,and fluorescence contrasts respectively.Moreover,an X-ray nano-CT experiment is performed with a 100 nm spatial resolution.Typical user experimental results from the fields of material science,biomedicine,paleontology,physics,chemistry,and environmental science obtained on the beamline are provided. | Hong-Lan Xie Biao Deng Guo-Hao Du Ya-Nan Fu Han Guo Yan-Ling Xue Guan-Yun Peng Fen Tao Ling Zhang Ti-Qiao Xiao | 2020 | Nuclear Science and Techniques2020，31，10： | 7 |
| 7 | Molecular Characterization and Correlation with β-lactam Resistance of Streptococcus pneumonia Isolates in Hangzhou,China显示文摘Penicillin-binding proteins(PBPs) are the target of β-lactam antibiotics(the major treatment for Streptococcus pneumoniae infections),and mutations in PBPs are considered as a primary mechanism for the development of β-lactam resistance in S.pneumoniae.This study was conducted to investigate the mutations in the PBPs of clinical S.pneumoniae isolates in Hangzhou,China,in correlation with β-lactam resistance.Results showed that 19 F was the predominant serotype(7/27) and 14 of the S.pneumoniae isolates were resistant to both penicillin G and cephalosporin.Genotyping results suggested that β-lactam-resistant isolates primarily exhibited single-site mutations in both the STMK and SRNVP motifs of pbp1 a in combination with double-site mutations in the STMK motif of pbp2 x,which might be the primary mechanisms underlying the β-lactam resistance of the isolates in this study. | chu mei fen liu xiao xiang zhang shao ni huang yan ying du peng wang li fang ji lei yan jie sun ai hua | 2018 | Biomedical and Environmental Sciences2018，31，5： | 7 |
| 8 | Radical microsurgical treatment of intramedullary spinal cord tumors显示文摘背景针的绳索肿瘤在完全的移动和最小的手术后的赤字瞄准的 intramedullary 的外科的治疗。这研究被承担评估 intramedullary 的 themicrosurgical 特征为外科和预后的针的绳索肿瘤和时间。方法有 intramedullary 的 21 个病人针的绳索肿瘤在 NanfangHospital 被对待,广州,中国后来, 2000 回顾地被学习。十五个病人是人和 6women, 2—60 年(平均数 29.28 年) 。13 个病人在颈的片断有肿瘤, 4 在髓质颈的片断, 1 在 cervicothoracic 分割,并且 3 在里面胸的脊骨。Allthe 病人由 laminectomy 通过以后的途径为肿瘤经历了微外科。Thetumor 通过背面的 myelotomy 被暴露,然后,肿瘤飞机从 entirerostrocaudal 区域小心地被移开。dura 习惯性地是 sutured。在占据太多针的片断的肿瘤的情况下,钛长带被使用重建脊椎的板并且保留脊梁骨桌子。所有病人在手术以后早受到先生成像。肿瘤的结果 Completeremoval 在 1 在 15 个病人,在 5 的小计移动,和部分切除术被做。神经病学的恢复首先与病人的外科手术前的神经病学的条件有关。有次要的神经病学的赤字的病人证明在早手术后的时期的感觉的马厩和马达功能或次要的损失,和神经病学的功能趋于与时间改善。但是那些几乎不能与重要或长期的赤字表明任何恢复。在肿瘤和正常绳索织物之间的解剖接口是影响外科的移动的程度的最重要的因素。结论 Intramedullary 针的绳索肿瘤主要发生在颈的片断,与是的 glioma 最普通的类型。Microsurgery 是选择,由肿瘤,飞机能完全是 resected 的主要治疗。当保留神经病学的功能时,优秀微外科的专家知识和肿瘤飞机的小心的识别对肿瘤的移动必要。钛长带固定是有用的重建脊椎的稳定性。病人的 Preoperativeneurological 条件是直接与他们的手术后的恢复有关。Weunderscore 早诊断的重要性和 intramedullaryspinal 绳索肿瘤的激进的微外科的治疗。 | PENG Lin QI Song-tao CHEN Zhuang FEN Wen-feng FANG Lu-xiong HUANG Li-jing CHENG Jiang-peng | 2006 | Chinese Medical Journal2006，，16： | 6 |
| 9 | Synthesis, structure and photocatalysis properties of two 3D Isostructural Ln (Ⅲ)-MOFs based 2,6-Pyridinedicarboxylic acid显示文摘Two new 3 D metal-organic frameworks(MOFs) named [Pr_2(PDA)3-3 H_2 O]-H_2 O(1) and[Nd_2(PDA)3-3 H_2 O] H_2 O(_2) [2,6-Pyridinedicarboxylic acid(H2 PDA)] were synthesized by solvothermal method. They were characterized by elemental analyses(EA), infrared spectroscopy(FT-IR), thermogravimetric analysis(TG), photocatalysis performance and single crystal X-ray diffraction studies(XRD).The XRD analysis indicated that MOFs(1) and(2) both belong to the monoclinic system with space group P2(1)/C. The structural model were drawn by the diamond software, and the structure revel that MOFs(1) and(2) adopt three-dimensional(3 D) frameworks constructed by cross-linking of one-dimensional(1 D) infinite chain secondary building unit(SBU) by 2,6-Pyridinedicarboxylic acid and hydrogen bond as linker. These frameworks feature channels inside which coordinated H_20 solvent molecules are located. Thermogravimetric analysis showed that both MOFs are thermally stable, the photocatalytic evaluation showed the materials have a good prospect in degration methylene blue. As for complex1, the decomposition efficiency of Methylene blue was about 91.08% after 130 min and the complex 2 reach 90.45% after 160 min under the sun light. | Chenchen Zhang Siyue Wei Lixian Sun Fen Xu Pengru Huang Hongliang Peng | 2018 | Journal of Materials Science & Technology2018，34，9： | 5 |
| 10 | Microporous carbon nanofibers prepared by combining electrospinning and phase separation methods for supercapacitor显示文摘Microporous carbon nanofibers(MCNFs) derived from polyacrylonitrile nanofibers were fabricated via electrospinning technology and phase separation in the presence of polyvinylpyrrolidone(PVP).PVP together with a mixed solvent of N,N-Dimethylformamide and dimethyl sulfoxide was used as poreforming agent.The influences of PVP content in casting solution on the structure and electrochemical performance of the MCNFs were also investigated.The highest capacitance of 200 F/g was obtained on a three-electrode system at a scan rate of 0.5 A/g.The good performance was owing to the high specific surface area and the large amount of micro-pores,which enhanced the absorption and the transportation efficiency of electrolyte ion during charge/discharge process.This research indicated that the combination of electrospinning and phase separation technology could be used to fabricate microporous carbon nanofibers as electrode materials for supercapacitors with high specific surface area and outstanding electrochemical performance. | Chang Liu Yongtao Tan Ying Liu Kuiwen Shen Bowu Peng Xiaoqin Niu Fen Ran | 2016 | Journal of Energy Chemistry2016，25，4： | 5 |
| 11 | The Changing Trends of HIV/AIDS in An Ethnic Minority Region of China: Modeling the Epidemic in Liangshan Prefecture, Sichuan Province显示文摘Objective This study was to investigate the HIV current situation in Liangshan prefecture, in order to predict prevalence and transmission trends. Methods Region-specific population, behavior, serosurveillence, and policy/program data (from 1995 to 2010) were gathered from various local and national organizations and applied to the Asian Epidemic Model (AEM) and used to derive estimates of future HIV prevalence, epidemic trends, and outcomes of intervention strategies. Results The AEM projections for 2020 included increased number of people living with HIV (PLHIV; to 136 617), increased HIV prevalence (2.51%), and 8037 deaths from acquired immunodeficiency syndrome (AIDS) in this region. However, the overall HIV incidence rate (per 10 000) was projected to decline from 27 in 2015 to 22 in 2020, largely due to a predicted decrease in HIV infection rate (per 10 000) from 658 in 2013 to 621 in 2020 among intravenous drug users. In contrast, the cases of HIV infection per 10 000 was projected to increase from 420 in 2010 to 503 in 2020 among men who have sex with men, and from 8 in 2010 to 15 in 2020 among the general population. The predominant risk factor for HIV transmission over the next decade in Liangshan was casual sex. Community-based outreach strategies to reduce injected drug use and casual sex, and to promote condom use, were predicted as effective interventions to decrease HIV transmission. Conclusion Implementation of a comprehensive public health program, with targeting to the region-specific at-risk populations, will help tomitigate HIV/AIDS spread in Liangshan. | LIU Shou WANG Qi Xing NAN Lei WU Chun Lin WANG Zhao Fen BAI Zhen Zhong LIU Li CAI Peng QIN Si LUAN Rong Sheng | 2013 | Biomedical and Environmental Sciences2013，26，7： | 5 |
| 12 | Vaccination against Schistosoma japonicum Infection by DNA Vaccine Encoding Sj22.7 Antigen显示文摘在鼠标的效果, recombinant 原生质标志 pcDNA3-Sj22.7 与调停 liposome 的方法习惯于 transfectHeLa 房间, Sj22.7 mRNA 和蛋白质的表达式用反向的抄写聚合酶链反应,钠 dodecylsulfate-polyacrylamide 凝胶电泳和蛋白质印迹被检验。然后, pcDNA3-Sj22.7 的能力在鼠标的种痘以后根据蠕虫减小率和鸡蛋减小率被分析免于 Schistosomajaponicum 挑战感染。特定的 IgG 抗体和 T 淋巴细胞增长反应的浆液层次也是坚定的。在挑战感染以后,驾驶 Sj22.7 的干扰素(IFN )-gamma andinterleukin (IL )-4 也被确定。结果证明 pcDNA3-Sj22.7 能表示 Sj22.7 mRNAand 在 vitro.Immunization 的蛋白质导致了29.70%的蠕虫减小率;鸡蛋减小率of47.25%(肝)并且51.73%(肠),并且25.90%的鸡蛋减小率(鸡蛋每女性),在 连接group.Enzyme 的免疫吸着剂试金和蛋白质印迹分析显示了的 pcDNA3-Sj22.7 建议重要反肥沃的正式就职那使对从与 pcDNA3-Sj22.7 使免疫的鼠标的 Sj22.7.Tlymphocytes 的产生特定的 IgG 显示出的鼠标免疫怒气房间的一种重要增长反应 torSj22.7.The 文化证明 IFN-gamma 的那分泌物增加了但是 IL-4decreased.The 结果显示由 pcDNA3-Sj22.7 的 DNA 种痘对足够对 S.japonicum 感染得到保护的免疫的重要层次。DNA 疫苗能导致重要细胞、体液的有免疫力的反应,并且显示占优势的 T 助手房间类型 1 类型免疫者回答,它在鼠标对挑战感染贡献保护的免疫。 | Gan DAI Shiping WANG Junlong YU Shaorui XU Xianchu PENG Zhuo HE Xueqin LIU Songhua ZHOU and Fen LIU Institute of Schistosomiasis Research.Xiangya School of Medicine,Central South University,Changsha 410078 China | 2007 | Acta Biochimica et Biophysica Sinica2007，39，1： | 5 |
| 13 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011，，1： | 4 |
| 14 | A new ellagitannin from Cleidion bracteosum显示文摘A new ellagitannin, named bractin (1), had been isolated from the dried aerial part of Cleidion bracteosum. Its structure was determined based on various of spectral analysis. | Peng Ju Yi Fen Wang Qiong Wang Shi De Luo | 2007 | Chinese Chemical Letters2007，18，3： | 2 |
| 15 | High prevalence of contact hypersensitivity to metals and preservatives in Chinese patients with atopic dermatitis显示文摘Atopic dermatitis(AD)is an inflammatory skin disease characterized by chronic recurrent dermatitis with profound pruritus.Most patients have personal and/or family history of atopic diseases.111 Allergy to air allergens and food allergens was regarded as an important feature of AD.There have been few studies for contact sensitization in patients with AD.The question remains if patch testing to a greater extent should be used as a screening tool in AD patients,to exclude hidden allergies possibly maintaining or aggravating their skin symptoms.In this study,w e compared patch test results between patients with AD and non-AD patients including patients with facial dermatitis,eczema,psoriasis,pruritus and urticaria,and including some healthy population. | Fen Peng Robert A.Schwartz Zhou Chen Jian-Zhong Zhang | 2019 | Chinese Medical Journal2019，，23： | 2 |
| 16 | Gastrodin ameliorates depression-like behaviors and up-regulates proliferation of hippocampal-derived neural stem cells in rats: Involvement of its anti-inflammatory action显示文摘 | Huaning Wang Ruiguo Zhang Yuting Qiao Fen Xue Huang Nie Ying Wang Zhengwu Peng Qingrong Tan | 2014 | Behavioural Brain Research2014，，： | 2 |
| 17 | Golden Promise barley(Hordeum vulgare) is a suitable candidate model host for investigation interaction with Heterodera avenae显示文摘Heterodera avenae(cereal cyst nematode, CCN) infects many cereal crops and causes serious yield losses worldwide. Interaction studies investigating H. avenae and its hosts are still in their infancy. In this study, a barley model plant, the Hordeum vulgare cultivar Golden Promise, was investigated for its potential as a candidate model host to study its interaction with H. avenae. CCN-infective juveniles were attracted by the root tips and gathered around the root elongation zones of Golden Promise on 0.7% water agar plates. The juveniles invaded the roots and developed successfully until maturation at 40 days after inoculation in sterile sand soil. The cryotomy and syncytium measurements indicated that the syncytia enlarged gradually throughout the development of the nematodes and caused the corresponding root regions to swell obviously. Quantitative real-time PCR analysis showed that the down-regulation of defence-related barley genes and up-regulation of development-related barley genes contribute to the understanding of compatible interaction between H. avenae and Golden Promise. Barley stripe mosaic virus(BSMV) virus-induced gene silencing(VIGS) can be used in the roots of Golden Promise. In conclusion, the Hordeum vulgare cultivar Golden Promise is a suitable candidate model host for interaction studies with Heterodera avenae. The studies presented above document the first CCN host that not only has published genome context but also be compatible to BSMV VIGS. | LUO Shu-jie KONG Ling-an PENG Huan HUANG Wen-kun CUI Jiang-kuan LIU Jing QIAO Fen JIAN Heng PENG De-liang | 2017 | Journal of Integrative Agriculture2017，16，7： | 2 |
| 18 | Guillain-Barre Syndrome Complicated on Postoperation on Renal Carcinoma and Meningioma显示文摘 | Shuai Xu Fen Peng Yang-Shuo Wang Shu Li Hai-Ying Liu | 2018 | Chinese Medical Journal2018，，9： | 2 |
| 19 | Mn,N co-doped Co nanoparticles/porous carbon as air cathode for highly efficient rechargeable Zn-air batteries Hide Author's Information显示文摘Oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)are generally catalyzed by precious metals(Pt)and metal oxides(IrO_(2))which still have many shortages including expensive price,poor selectivity and undesirable stability.In this work,we report a Mn0-doped CoN_(x) on N-doped porous carbon(Mn-CoN_(x)/N-PC)composite from carbonizing metal-organic framework(MOF)derivative as the dual-functional catalyst to boost both the ORR and OER performances.Owing to the strong coordination effect between nitrogen and metal elements,the introduction of N can obviously improve the content of Co-N-C active sites for ORR.Meanwhile,the Mn-doping significantly regulates the electronic structure of the Co element and increases the content of Co^(0) which provide efficient OER active sites.Mn-CoN_(x)/N-PC catalyst delivers super dual-functional activity with a half-wave potential of 0.85 V,better than the 20%Pt/C catalyst(0.82 V).When used in Zn-air batteries for testing,Mn-CoN_(x)/N-PC electrocatalyst shows a high power density(145 mW·cm^(−2))and good cycle performance. | Hanzhen Zheng Fei Ma Hongcen Yang Xiaogang Wu Rui Wang Dali Jia Zhixia Wang Niandi Lu Fen Ran Shanglong Peng | 2022 | Nano Research2022，15，3： | 2 |
| 20 | The prevalence of dementia in urban and rural areas of China显示文摘 | Jianping Jia Fen Wang Cuibai Wei Aihong Zhou Xiangfei Jia Fang Li Muni Tang Lan Chu Youlong Zhou Chunkui Zhou Yong Cui Qi Wang Weishan Wang Peng Yin Nan Hu Xiumei Zuo Haiqing Song Wei Qin Liyong Wu Dan Li Longfei Jia Juexian Song Ying Han Yi Xing Peijie Y | 2013 | Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association2013，，： | 2 |
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