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| 1 | Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC)is a poor-prognosis cancer type with limited understanding of its molecular etiology.Using 508 ESCC genomes,we identified five novel significantly mutated genes and uncovered mutational signature clusters associated with metastasis and patients’outcomes.Several functional assays implicated that NFE2L2 may act as a tumor suppressor in ESCC and that mutations in NFE2L2 probably impaired its tumor-suppressive function,or even conferred oncogenic activities.Additionally,we found that the NFE2L2 mutations were significantly associated with worse prognosis of ESCC.We also identified potential noncoding driver mutations including hotspot mutations in the promoter region of SLC35E2 that were correlated with worse survival.Approximately 5.9%and 15.2%of patients had high tumor mutation burden or actionable mutations,respectively,and may benefit from immunotherapy or targeted therapies.We found clinically relevant coding and noncoding genomic alterations and revealed three major subtypes that robustly predicted patients’outcomes.Collectively,we report the largest dataset of genomic profiling of ESCC useful for developing ESCC-specific biomarkers for diagnosis and treatment. | Yongping Cui Hongyan Chen Ruibin Xi Heyang Cui Yahui Zhao Enwei Xu Ting Yan Xiaomei Lu Furong Huang Pengzhou Kong Yang Li Xiaolin Zhu Jiawei Wang Wenjie Zhu Jie Wang Yanchun Ma Yong Zhou Shiping Guo Ling Zhang Yiqian Liu Bin Wang Yanfeng Xi Ruifang Sun Xiao Yu Yuanfang Zhai Fang Wang Jian Yang Bin Yang Caixia Cheng Jing Liu Bin Song Hongyi Li Yi Wang Yingchun Zhang Xiaolong Cheng Qimin Zhan Yanhong Li Zhihua Liu-Show | 2020 | Cell Research2020，30，10： | 19 |
| 2 | A novel fault tolerant permanent magnet synchronous motor with improved optimal torque control for aerospace application显示文摘Improving fault tolerant performance of permanent magnet synchronous motor has always been the central issue of the electrically supplied actuator for aerospace application. In this paper, a novel fault tolerant permanent magnet synchronous motor is proposed, which is characterized by two stators and two rotors on the same shaft with a circumferential displacement of mechanical angle of 4.5. It helps to reduce the cogging torque. Each segment of the stator and the rotor can be considered as an 8-pole/10-slot five-phase permanent magnet synchronous motor with concentrated, single-layer and alternate teeth wound winding, which enhance the fault isolation capacity of the motor. Furthermore, the motor has high phase inductance to restrain the short-circuit current. In addition, an improved optimal torque control strategy is proposed to make the motor work well under the open-circuit fault and short-circuit fault conditions. Simulation and experiment results show that the proposed fault tolerant motor system has excellent fault tolerant capacity, which is able to operate continuously under the third open-circuit fault and second shortcircuit fault condition without system performance degradation, which was not available earlier. | Guo Hong Xu Jinquan Kuang Xiaolin | 2015 | Chinese Journal of Aeronautics2015，28，2： | 16 |
| 3 | A new feathered maniraptoran dinosaur fossil that fills a morphological gap in avian origin显示文摘Recent fossil discoveries have substantially reduced the morphological gap between non-avian and avian dinosaurs, yet avians including Archaeopteryx differ from non-avian theropods in their limb proportions. In particular, avians have proportionally longer and more robust forelimbs that are capable of supporting a large aerodynamic surface. Here we report on a new maniraptoran dinosaur, Anchiornis huxleyi gen. et sp. nov., based on a specimen collected from lacustrine deposits of uncertain age in western Liaoning, China. With an estimated mass of 110 grams, Anchiornis is the smallest known non-avian theropod dinosaur. It exhibits some wrist features indicative of high mobility, presaging the wing-folding mechanisms seen in more derived birds and suggesting rapid evolution of the carpus. Otherwise, Anchiornis is intermediate in general morphology between non-avian and avian dinosaurs, particularly with regard to relative forelimb length and thickness, and represents a transitional step toward the avian condition. In contrast with some recent comprehensive phylogenetic analyses, our phylogenetic analysis incorporates subtle morphological variations and recovers a conventional result supporting the monophyly of Avialae. | XU Xing ZHAO Qi NORELL Mark SULLIVAN Corwin HONE David ERICKSON Gregory WANG XiaoLin HAN FengLu GUO Yu | 2009 | Chinese Science Bulletin2009，54，3： | 15 |
| 4 | Influences of different types of magnetic fields on HCFC-141b gas hydrate formation processes显示文摘In this study, visualizations and experiments are carried out on the influence of static and rotating magnetic fields on the characteristics of HCFC-141b gas hydrate formation, such as crystallization form, formation temperature and induction time. It has been found that a proper rotating magnetic field can considerably improve the low-pressure gas hydrate formation process, especially in increasing the formation temperature and shortening the induction time. The mor- phology of the gas hydrate formation appears rather complex and compact. However, a proper static magnetic field can make the gas hydrate crystal more organized, which will be benefit to heat transfer. | SHU Bifen MA Xiaolin GUO Kaihua LI Jianhong | 2004 | Science China Chemistry2004，47，5： | 14 |
| 5 | Retrospective study of Traditional Chinese Medicine treatment of type 2 diabetes mellitus显示文摘OBJECTIVE: To provide clinical evidence in support of Dahuang Huanglian Xiexin decoction(DHXD) to treat type 2 diabetes mellitus(T2DM) and to introduce a new treatment option for clinicians.METHODS: Retrospective analysis was used to evaluate DHXD for the treatment of T2DM by analyzing clinical records of 183 cases. Patients with T2DM who met the inclusion criteria between January 1,2013 and January 1, 2014 were enrolled. The effects of the treatment were evaluated by the changes in fasting blood-glucose(FBG), postprandial blood sugar(PBG), hemoglobin A1c(Hb Alc), blood lipid profiles and body mass index(BMI) at 1, 2, 3 and 6 months. The changes in main symptoms were alsoevaluated. The dosage of Huanglian(Rhizoma Coptidis) and related factors were analyzed.RESULTS: There was a significant improvement in mean Hb A1C at 3 and 6 months after DHXD treatment compared with the baseline level(P < 0.01).There were also significant improvements in FBG,PBG, blood lipid series and BMI. DHXD also improved the main symptoms of stomach and intestine excessive heat syndrome in patients with obese T2DM. Huanglian(Rhizoma Coptidis) was the most frequently used in 678 clinical visits, the dosage of Huanglian(Rhizoma Coptidis) was related to age, BMI, DM duration, the level of blood glucose,and use of Western hypoglycemic drugs.CONCLUSION: This study suggests that DHXD could decrease blood glucose and improve T2DM symptoms and reduce body weight. The use of DHXD may indicate a new optional treatment for T2 DM. | Pang Bing Guo Jing Zhao Linhua Zhao Xiyan Zhou Qiang Tong Xiaolin | 2016 | Journal of Traditional Chinese Medicine2016，36，3： | 11 |
| 6 | Structure of the receptor-activated human TRPC6 and TRPC3 ion channels显示文摘TRPC6 和 TRPC3 是属于正规短暂受体潜力(TRPC ) 的家庭的激活受体的 nonselective 阳离子隧道隧道。他们被 diacylglycerol 激活,一个类脂化合物秒送信人。TRPC6 和 TRPC3 涉及许多生理的过程并且在人的基因疾病含有。这里我们在场在有最新识别的高亲密关系的禁止者 BTDM 的建筑群的人的 TRPC6 homotetramer 的结构由单个粒子的 cryo 电子显微镜学解决了到 3.8?分辨率。我们也在 4.4 点介绍人的 TRPC3 的结构吗?分辨率。这些结构显示出塑造钟的 cytosolic 层在保持 transmembrane 层的二层的体系结构。包括 N 终端 ankyrin 重复和 C 终端卷卷, cytosolic 领域的广泛的内部子单元的相互作用贡献 tetramer 集会。高亲密关系的禁止者 BTDM 在 S5-S6 毛孔领域和电压之间挤像传感器的领域禁止隧道开。我们的结构揭开 TRPC 隧道的分子的建筑学并且为理解这些隧道的机制提供一个结构的基础。 | Qinglin Tang Wenjun Guo Li Zheng Jing-Xiang Wu Meng Liu Xindi Zhou Xiaolin Zhang Lei Chen | 2018 | Cell Research2018，28，7： | 10 |
| 7 | Serum interleukin-10 levels and adverse events in patients with acute coronary syndrome: a systematic review and meta-analysis显示文摘 | Liu Jun Jia Yanjun Li Xiaolin Xu Ruixia Zhu Chenggang Guo Yuanlin Wu Naqiong Li Jianjun | 2014 | Chinese Medical Journal2014，，1： | 6 |
| 8 | Value of MR perfusion imaging after intervention treatment of hepatic cancer显示文摘目的将在评估肝的癌症的干预治疗的药品效果调查先生灌注成像的价值。36 个病人在干预治疗以后经历了先生灌注成像的方法。量子化结果在癌残余和良性的组织之间被不同。并且诊断精确性被判定。在那里的结果是在在在外科和良性的改进区域以后的残余肿瘤之间的吝啬的 MSI 的有效差量。残余肿瘤的时间目的曲线被观察很快上升到达山峰,而改进织物的慢慢地上升了到达山峰。察觉上的 PWI 的敏感和特性剩余或再发性瘤分别地是 0.89 和 0.73。结论 PWI 是能被用来在外科以后区分肝织物状况的一种很敏感的成像技术。早贡献的 PWI 上演诊断和动态监视后面的 HCC 外科。 | You Guo ZhaoChen Xiaolin Zheng Chengfu Tang Xijin He Yikai Xu | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，1： | 6 |
| 9 | Synergistic effect of Pt nanoparticles and micro-mesoporous ZSM-5 in VOCs low-temperature removal显示文摘Micro-mesoporous ZSM-5 zeolites were obtained by the post-treatment of tetrahydroxy ammonium hydroxide(TPAOH) solution with different concentration.The hierarchical pore structure formed during the desilication process facilitates the dispersion of Pt nanoparticles and Pt/ZSM-5 catalysts exhibit rather high catalytic activity for the deep oxidation of various VOCs at low temperature.The catalyst treated with TPAOH of 0.1 mol/L(Pt/ZSM-5(0.1)) shows the lowest degradation temperature(T90%) of 128 and 142℃, respectively for benzene and n-hexane.Compared with the untreated Pt/ZSM-5 catalyst, the abundant mesopores, small Pt particle size and finely dispersed Pt contribute to the superior catalytic activity and stability of the Pt/ZSM-5 catalysts for VOCs removal.More importantly, the existence of H_(2)O in the feed gases hardly affected the activity of Pt/ZSM-5(0.1) catalyst at the low reaction temperature of 128℃, which is very important for VOCs low-temperature removal in the future practical applications. | Jialu Wang Xiaolin Guo Yijun Shi Renxian Zhou | 2021 | Journal of Environmental Sciences2021，33，9： | 6 |
| 10 | The relations among the three kinds of conditional risk measures显示文摘Let(Ω,E,P)be a probability space,F a sub-σ-algebra of E,Lp(E)(1 p+∞)the classical function space and Lp F(E)the L0(F)-module generated by Lp(E),which can be made into a random normed module in a natural way.Up to the present time,there are three kinds of conditional risk measures,whose model spaces are L∞(E),Lp(E)(1 p<+∞)and Lp F(E)(1 p+∞)respectively,and a conditional convex dual representation theorem has been established for each kind.The purpose of this paper is to study the relations among the three kinds of conditional risk measures together with their representation theorems.We first establish the relation between Lp(E)and Lp F(E),namely Lp F(E)=Hcc(Lp(E)),which shows that Lp F(E)is exactly the countable concatenation hull of Lp(E).Based on the precise relation,we then prove that every L0(F)-convex Lp(E)-conditional risk measure(1 p+∞)can be uniquely extended to an L0(F)-convex Lp F(E)-conditional risk measure and that the dual representation theorem of the former can also be regarded as a special case of that of the latter,which shows that the study of Lp-conditional risk measures can be incorporated into that of Lp F(E)-conditional risk measures.In particular,in the process we find that combining the countable concatenation hull of a set and the local property of conditional risk measures is a very useful analytic skill that may considerably simplify and improve the study of L0-convex conditional risk measures. | GUO TieXin ZHAO ShiEn ZENG XiaoLin | 2014 | Science China Mathematics2014，57，8： | 6 |
| 11 | Effect of PdOx structure properties on catalytic performance of Pd/Ce0.67Zr0.33O2 catalyst for CO,HC and NOx elimination显示文摘Pd/Ce0.67Zr0.33O2 catalyst was pretreated in different atmosphere respectively, and characterized by CO chemical adsorption, XPS, HR-TEM, H2-TPR, Raman, OSC and in situ DRIFTS to investigate the effect of the structure properties of PdOx species on the catalytic performance for CO, HC and NOx elimination. The results show that Pd/CZ catalyst pretreated in air atmosphere has higher oxidation activity of HC due to having high Pd dispersion and strong interaction between PdOx and CZ support. Pd/CZ-H catalyst pretreated in reducing atmosphere exhibits better catalytic performance of NOx elimination because of having relatively big Pd particle size, more Pd species in metallic state and higher concentration of oxygen vacancies. While for the Pd/CZ-RG catalyst pretreated in reactant atmosphere, strong adsorption of HC species on the surface of catalysts would lead to a part of active sites being covered, which inhibits HC and NO conversions. | Ting Wang Xiaolin Guo Siyu Lin Renxian Zhou | 2019 | Journal of Rare Earths2019，37，7： | 4 |
| 12 | Confining shell-sandwiched Ag clusters in MnO_(2)-CeO_(2)hollow spheres to boost activity and stability of toluene combustion显示文摘Supported noble metal catalysts have the promising application in volatile organic compounds(VOCs)catalytic combustion but suffer from the deactivation due to noble metal sintering at high temperatures.Herein,we report the construction of shellsandwiched MnO_(2)-Ag-CeO_(2)hollow spheres with remarkable sintering resistance and high activity in toluene combustion.Ag clusters were sandwiched between outer MnO_(2)and inner CeO_(2)shell to enlarge and stabilize metal–support active interface.The unique hollow structure could alter the electronic states of catalysts sites and increase the adsorbed site of reactant molecules.Meanwhile,Mn–Ag–Ce multi-interfaces in MnO_(2)-Ag-CeO_(2)could facilitate the sustainable activation and the stable release of oxygen species via a tandem transfer.The oxygen species at Ag–Mn interface perimeter were instantly replenished by Ag–Ce interface to accelerate a deep oxidation of intermediates,guaranteeing the opening of benzene ring to generate maleic anhydride.This investigation provides a promising method for constructing efficient and sintering-resistant cluster catalysts for VOCs oxidation. | Menglan Xiao Xueqin Yang Yue Peng Yucong Guo Yuechang Wei Maofa Ge Xiaolin Yu | 2022 | Nano Research2022，15，8： | 4 |
| 13 | Shumian capsule(舒眠胶囊) improves symptoms of sleep mood disorder in convalescent patients of Corona Virus Disease 2019显示文摘OBJECTIVE:To evaluate the clinical effectiveness of Shumian capsule(舒眠胶囊)in improving the symptoms of insomnia,anxiety,depression,and other symptoms of convalescent patients of COVID-19.METHODS:Totally 200 patients were collected and randomly divided into experiment group(n=100)and control group(n=100).The control group was treated with Shumian capsule simulator,and the experiment group was treated with Shumian capsule.The improvement of TCM symptom score,the total effective rate and symptom disappearance rate of TCM symptoms in the two groups before and after treatment were observed,and the clinical effect was evaluated.RESULTS:One week after treatment,the scores of anxiety symptoms in the experiment group were significantly different from those in the control group(P<0.05),but there was no significant difference in the scores of insomnia and depression between the experiment group and the control group(P>0.05).There was no significant difference in the total effective rate and disappearance rate of TCM symptoms of insomnia,anxiety and depression between the experiment group and the control group(P>0.05).After 2 weeks of treatment,the scores of insomnia,anxiety,depression and the total effective rate of TCM symptoms in the experiment group were significantly different from those in the control group(P<0.05).There was no significant difference in the disappearance rate of insomnia,anxiety and depression between the experiment group and the control group(P>0.05).There were no significant differences in heart rate,respiration,systolic blood pressure and diastolic blood pressure between the experiment group and the control group(P>0.05).CONCLUSION:Shumian capsule can significantly improve the symptoms of insomnia,anxiety and depression in COVID-19’s convalescent patients with sleep and mood disorders. | LI Li AN Xuedong ZHANG Qing TAO Junxiu HE Jing CHEN Yun LI Kejian LIU Ru GUO Juan ZHANG Hao TONG Xiaolin BA Yuanming | 2021 | Journal of Traditional Chinese Medicine2021，41，6： | 4 |
| 14 | A simple model of radial nerve injury in the rhesus monkey to evaluate peripheral nerve repair显示文摘Current research on bone marrow stem cell transplantation and autologous or xenogenic nerve transplantation for peripheral nerve regeneration has mainly focused on the repair of peripheral nerve defects in rodents.In this study,we established a standardized experimental model of radial nerve defects in primates and evaluated the effect of repair on peripheral nerve injury.We repaired 2.5-cm lesions in the radial nerve of rhesus monkeys by transplantation of autografts,acellular allografts,or acellular allografts seeded with autologous bone marrow stem cells.Five months after surgery,regenerated nerve tissue was assessed for function,electrophysiology,and histomorphometry.Postoperative functional recovery was evaluated by the wrist-extension test.Compared with the simple autografts,the acellular allografts and allografts seeded with bone marrow stem cells facilitated remarkable recovery of the wrist-extension functions in the rhesus monkeys.This functional improvement was coupled with radial nerve distal axon growth,a higher percentage of neuron survival,increased nerve fiber density and diameter,increased myelin sheath thickness,and increased nerve conduction velocities and peak amplitudes of compound motor action potentials.Furthermore,the quality of nerve regeneration in the bone marrow stem cells-laden allografts group was comparable to that achieved with autografts.The wrist-extension test is a simple behavioral method for objective quantification of peripheral nerve regeneration. | Dong Wang Xijun Huang Guo Fu Liqiang Gu Xiaolin Liu Honggang Wang Jun Hu Jianhua Yi Xiaofeng Niu Qingtang Zhu | 2014 | Neural Regeneration Research2014，9，10： | 3 |
| 15 | Optically Stimulated Luminescence(OSL) Chronology of the Dehenglong Landslide from Longyang Gorge to Liujia Gorge along Upper Yellow River, China显示文摘Giant landslides are common along the upper Yellow River from Longyang Gorge to Liujia Gorge, and some of them even blocked and dammed the upper Yellow River. Chronology is inevitable in studying the mechanism of giant landslides. Controversy exists about the chronology of those giant landslides, and some have not yet dated. The Dehenglong landslide is the largest one among them. In this study, OSL samples were collected from lacustrine silty sediments and loess directly overlying the landslide sediments, as well as fault sediments related to the landslide. This landslide yielded an age of 89 ± 8 ka, which is identical with the fault age of 73 ± 5 ka at two sigma errors. The agreement of a topographic analysis and the absolute age of landslides imply that the formation of the Dehenglong landslide is strongly correlated with the tectonic activity. | GUO Xiaohua LAI Zhongping LU Yudong LI Xiaolin SUN Zheng | 2015 | Acta Geologica Sinica(English Edition)2015，89，1： | 3 |
| 16 | Flexible polyimide-based hybrid optoelectric neural interface with 16 channels of micro-LEDs and electrodes显示文摘In this paper,a polyimide-based flexible device that integrates 16 micro-LEDs and 16 IrO_(x)-modified microelectrodes for synchronous photostimulation and neural signal recording is presented.The 4×4 micro-LEDs(dimensions of 220×270×50μm^(3),700μm pitch)are fixed in the SU-8 fence structure on a polyimide substrate and connected to the leads via a wire-bonding method.The recording electrodes share a similar fabrication process on the polyimide with 16 microelectrode sites(200μm in diameter and 700μm in pitch)modified by iridium oxide(IrO_(x)).These two subparts can be aligned with alignment holes and glued back-to-back by epoxy,which ensures that the light from the LEDs passes through the corresponding holes that are evenly distributed around the recording sites.The long-term electrical and optical stabilities of the device are verified using a soaking test for 3 months,and the thermal property is specifically studied with different duty cycles,voltages,and frequencies.Additionally,the electrochemical results prove the reliability of the IrO_(x)-modified microelectrodes after repeated pressing or friction.To evaluate the tradeoff between flexibility and strength,two microelectrode arrays with thicknesses of 5 and 10μm are evaluated through simulation and experiment.The proposed device can be a useful mapping optogenetics tool for neuroscience studies in small(rats and mice)and large animal subjects and ultimately in nonhuman primates. | Bowen Ji Zhejun Guo Minghao Wang Bin Yang Xiaolin Wang Wen Li Jingquan Liu | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 17 | A putative bHLH transcription factor is a candidate gene for male sterile 32,a locus affecting pollen and tapetum development in tomato显示文摘The tomato(Solanum lycopersicum)male sterile 32(ms32)mutant has been used in hybrid seed breeding programs largely because it produces no pollen and has exserted stigmas.In this study,histological examination of anthers revealed dysfunctional pollen and tapetum development in the ms32 mutant.The ms32 locus was fine mapped to a 28.5 kb interval that encoded four putative genes.Solyc01g081100,a homolog of Arabidopsis bHLH10/89/90 and rice EAT1,was proposed to be the candidate gene of MS32 because it contained a single nucleotide polymorphism(SNP)that led to the formation of a premature stop codon.A codominant derived cleaved amplified polymorphic sequence(dCAPS)marker,MS32D,was developed based on the SNP.Real-time quantitative reverse-transcription PCR showed that most of the genes,which were proposed to be involved in pollen and tapetum development in tomato,were downregulated in the ms32 mutant.These findings may aid in marker-assisted selection of ms32 in hybrid breeding programs and facilitate studies on the regulatory mechanisms of pollen and tapetum development in tomato. | Xiaoyan Liu Mengxia Yang Xiaolin Liu Kai Wei Xue Cao Xiaotian Wang Xiaoxuan Wang Yanmei Guo Yongchen Du Junming Li Lei Liu Jinshuai Shu Yong Qin Zejun Huang | 2019 | Horticulture Research2019，6，1： | 3 |
| 18 | Task-Aware Flow Scheduling with Heterogeneous Utility Characteristics for Data Center Networks显示文摘With the continuous enrichment of cloud services, an increasing number of applications are being deployed in data centers. These emerging applications are often communication-intensive and data-parallel, and their performance is closely related to the underlying network. With their distributed nature, the applications consist of tasks that involve a collection of parallel flows. Traditional techniques to optimize flow-level metrics are agnostic to task-level requirements, leading to poor application-level performance. In this paper, we address the heterogeneous task-level requirements of applications and propose task-aware flow scheduling. First, we model tasks' sensitivity to their completion time by utilities. Second, on the basis of Nash bargaining theory, we establish a flow scheduling model with heterogeneous utility characteristics, and analyze it using Lagrange multiplier method and KKT condition. Third, we propose two utility-aware bandwidth allocation algorithms with different practical constraints. Finally, we present Tasch, a system that enables tasks to maintain high utilities and guarantees the fairness of utilities. To demonstrate the feasibility of our system, we conduct comprehensive evaluations with realworld traffic trace. Communication stages complete up to 1.4 faster on average, task utilities increase up to 2.26,and the fairness of tasks improves up to 8.66 using Tasch in comparison to per-flow mechanisms. | Fang Dong Xiaolin Guo Pengcheng Zhou Dian Shen | 2019 | Tsinghua Science and Technology2019，24，4： | 2 |
| 19 | Paratesticular fibrous pseudotumor: a report of five cases and literature review显示文摘Paratesticular 含纤维的 pseudotumor 是从 intrascrotal 织物发源的一个稀罕良性的肿瘤,例如 tunica vaginalis, epididymis,或精索。我们的医院里的含纤维的 pseudotumor 的五个案例回顾地被考察,并且临床的表明被分析。单方的小瘤,大小写在 tunica vaginalis 定位了的包括的小瘤和二个案例的三个案例在 epididymis 定位了,经历了单方的小瘤的本地切除。在 tunica vaginalis 的弥漫的增厚的二个案例经历了恰好激进的 orchiectomy。手术后的病理学的检查证明所有是含纤维的 pseudotumors。没有复发, 26 个月的平均后续为所有病人显示出平静结果。含纤维的 pseudotumor 不是一个瘤但是反应含纤维的煽动性的增生。权威的诊断要求病理学的检查。当因为潜在的恶意的明显的证据的缺乏,可能、本地的切除应该被执行时,激进的 orchiectomy 应该被避免。 | Zhicheng Zhang Jun Yang Mingchao Li Wei Cai Qingquan Liu Tao Wang Xiaolin Guo ShaogangWang Jihong Liu ZhangqunYe | 2014 | Frontiers of Medicine2014，8，4： | 2 |
| 20 | Ultra-low thermal conductivity of two-dimensional phononic crystals in the incoherent regime显示文摘Two-dimensional silicon phononic crystals have attracted extensive research interest for thermoelectric applications due to their reproducible low thermal conductivity and sufficiently good electrical properties.For thermoelectric devices in high-temperature environment,the coherent phonon interference is strongly suppressed;therefore phonon transport in the incoherent regime is critically important for manipulating their thermal conductivity.On the basis of perturbation theory,we present herein a novel phonon scattering process from the perspective of bond order imperfections in the surface skin of nanostructures.We incorporate this strongly frequency-dependent scattering rate into the phonon Boltzmann transport equation and reproduce the ultra low thermal conductivity of holey silicon nanostructures.We reveal that the remarkable reduction of thermal conductivity originates not only from the impediment of low-frequency phonons by normal boundary scattering,but also from the severe suppression of high-frequency phonons by surface bond order imperfections scattering.Our theory not only reveals the role of the holey surface on the phonon transport,but also provide a computation tool for thermal conductivity modification in nanostructures through surface engineering. | Guofeng Xie Zhifang Ju Kuikui Zhou Xiaolin Wei Zhixin Guo Yongqing Cai Gang Zhang | 2018 | npj Computational Materials2018，，1： | 2 |
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