|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of Chaiqinchengqi decoction on inositol requiring enzyme 1α in alveolar macrophages of dogs with acute necrotising pancreatitis induced by sodium taurocholate显示文摘OBJECTIVE: To investigate the effect of Chaiqinchengqi decoction(CQCQD) on inositol requiring enzyme 1α(IRE1α) in alveolar macrophages(AMs)of the dog model of acute necrotising pancreatitis(ANP) induced by sodium taurocholate.METHODS: Fifteen beagle dogs were randomised into a control group,ANP group and CQCQD group(n = 5 per group). ANP was induced by a retrograde duct injection of 50 mg/kg of 5% sodium taurocholate. The dogs in the control group received injections of the same volume of saline as the sodium taurocholate. After the models were induced,the dogs in the CQCQD group were administered 10 m L/kg CQCQD every 2 h for 6 h. Two hours after the last administration of either CQCQD or saline,they were sacrificed by anaesthesia. AMs were collected to determine the IRE1α and Interleukin-1β(IL-1β)m RNA and protein expression,and pancreatic tissues were collected for histopathology analysis.RESULTS: Compared with the ANP group,the m RNA and protein expression of IRE1α and the protein expression of IL-1β of AMs in the CQCQD group were significantly down-regulated,and the pancreatic histopathology score of the CQCQD group also was lower. There was no significant difference in the m RNA expression of IL-1β of AMs between the two groups.CONCLUSION: The CQCQD-induced down-regulation of the IL-1β protein expression may involve the down-regulation of the m RNA and protein expression of IRE1α in AMs. | Guo Jia Wang Xiaoxiang Luo Ruijie Zhang Xiaoxin Yang Xiaonan Xia Qing Xue Ping | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 4 |
| 2 | Implantable CMOS neuro-stimulus chip for visual prosthesis显示文摘A prototype chip with 2×2 pixels for implanting in blind patients affected by outer retinal degeneration is presented in this paper.This visual prosthesis chip imitates the degenerated photoreceptor cells,senses the incident light and stimulates the remaining healthy layers of retina or optic nerve.Each pixel integrates photodiode and stimulus pulse generator,converting the illumination on the eyes into 3-bit resolution bi-phasic current pulses.On-chip charge cancellation modules are used to discharge each electrode site for tissue safety.The prototype chip is designed and fabricated in 0.18-μm N-well CMOS (complementary metal oxide semiconductor) 1P6M Mix-signal process,with a ±2.5 V dual voltage supply.The functionality of the fabricated chip is demonstrated on anesthetized rabbits.Neural responses in visual cortex are successfully evoked by the neuro-stimulus chip through an on-board trigger interface and flexible electrode. | ZHANG Xu PEI WeiHua HUANG BeiJu WANG ShuJing GUAN Ning GUO Kai WANG Yu GUI Qiang CHEN Jin WANG Kai WU HuiJuan LI XiaoXin LI Kai CHEN HongDa | 2011 | Science China(Information Sciences)2011，54，4： | 3 |
| 3 | Changes in Soil Enzyme Activity and Nutrient Content in Different Years of Continuous Cropping Tobacco Fields显示文摘In order to find out changes in the main fertility indicators of continuous cropping tobacco fields in Henan Province with years of continuous cropping,5 typical tobacco fields( Jia County,Shaoling District,Fangcheng County,Xiangcheng County,and Song County) were studied. Indicators in question included activity of main enzymes( sucrase,urease,catalase,and acid phosphatase),p H value,organic matters,total nitrogen,available phosphorus and available potassium. The results indicate that in most tobacco fields,the activity of sucrase and urease increased in two years of continuous cropping,later,it showed a declining trend with increase in years of continuous cropping; in some fields,it directly declined with increase in years of continuous cropping; the activity of catalase increased in two years of continuous cropping,later,it showed a declining trend with increase in years of continuous cropping,and it became stable after three years of continuous cropping;generally,the activity of acid phosphatase declined with increase in the years of continuous cropping within 3 years continuous cropping,later,it became stable. Except Fangcheng County,the soil p H value of other districts( counties) generally declined with increase in years of continuous cropping,and it was in the range of 5. 6-6. 8. With the increase in continuous cropping,the soil organic matters( SOM) in tobacco fields of Jia County and Song County declined,changes of SOM in tobacco fields of Fangcheng County and Xiangcheng County were not obvious,and SOM showed the trend of first decline then rise in Shaoling District. In most tobacco fields( Jia County,Xiangcheng County,and Song County),the total nitrogen showed a declining trend; in Shaoling District,it showed a trend of first decline then rise; in Fangcheng County,it showed a rising trend. The available phosphorus firstly slightly declined then rose in tobacco fields of Shaoling District and Song County; it showed a trend of first rise then decline in Jia County; there were no obvious changes in Fangcheng County and Xiangcheng County. Changes in the available potassium were different in tobacco fields. In sum,there are certain rules for changes in soil enzyme activity and nutrient content in tobacco fields in Henan Province,but changes are not completely the same. It is concluded that the site conditions and farming activities exert a certain influence on soil enzyme activity,p H value,organic matters,and nitrogen,phosphorus and potassium content. Therefore,to solve obstacles in continuous cropping of tobacco fields,different regions should take different measures. | Jifeng CHEN Hui SUN Yang XIA Kaixuan CAI Hongyuan LIU Yuanyuan LI Ruiliang GUO Bei HOU Shuai FENG Xiaoxin JIANG | 2017 | Asian Agricultural Research2017，9，5： | 2 |
| 4 | An empirical model of the global distribution of plasmaspheric hiss based on Van Allen Probes EMFISIS measurements显示文摘Using wave measurements from the EMFISIS instrument onboard Van Allen Probes,we investigate statistically the spatial distributions of the intensity of plasmaspheric hiss waves.To reproduce these empirical results,we establish a fitting model that is a thirdorder polynomial function of L-shell,magnetic local time(MLT),magnetic latitude(MLAT),and AE*.Quantitative comparisons indicate that the model’s fitting functions can reflect favorably the major empirical features of the global distribution of hiss wave intensity,including substorm dependence and the MLT asymmetry.Our results therefore provide a useful analytic model that can be readily employed in future simulations of global radiation belt electron dynamics under the impact of plasmaspheric hiss waves in geospace. | JingZhi Wang Qi Zhu XuDong Gu Song Fu JianGuang Guo XiaoXin Zhang Juan Yi YingJie Guo BinBin Ni Zheng Xiang | 2020 | Earth and Planetary Physics2020，4，3： | 2 |
| 5 | Targeting of integrin-linked kinase with a small interfering RNA suppresses progression of experimental proliferative vitreoretinopathy显示文摘 | Lili Guo Wenzhen Yu Xiaoxin Li Gang Zhao Jianhong Liang Peiying He Kai Wang Peng Zhou Yanrong Jiang Mingwei Zhao | 2008 | Experimental Eye Research2008，，6： | 1 |
| 6 | Risk Assessment and Management of Electricity Markets: A Review with Suggestions显示文摘Power industry deregulation has changed the determination of electricity prices from administration approval to market clearing.Affected by multiple random factors,the market prices may fluctuate sharply or significantly increase under extreme conditions,jeopardizing the normal operation of markets.In order to effectively deal with market risks,it is essential to develop the corresponding risk-control mechanisms,especially for spot market pilots.Therefore,this paper presents an overview on the risk assessment and management schemes which are widely used in the electricity markets.First,the key issues for evaluating market risks through inherent uncertainties and market power are summarized,including analysis models and quantitative metrics.Moreover,a comprehensive review of risk management and market supervision in typical electricity markets is presented.Specifically,a multi-time risk-control framework utilized by regulators is introduced to demonstrate the available schemes to reduce market risks.In addition,the various derivative contracts and portfolio optimizations are reviewed to help market participants hedge against market risks.Finally,suggestions for the development of risk management measures in spot market pilots are proposed.The summarized experience in this paper can provide useful references and guidelines for developing risk-control mechanisms in electricity markets. | Minglei Bao Yi Ding Xiaoxin Zhou Chao Guo Changzheng Shao | 2021 | CSEE Journal of Power and Energy Systems2021，7，6： | 1 |
| 7 | A low-com- plexity adaptive co-channel interference removal scheme for COFDM systems 显示文摘 | ZHANG Xiaoxin GUO Hongbo ZHAO Yuping | 2010 | IEEE Transactions on Consumer Elec- tronics2010，56，2： | 1 |
| 8 | Interaction between neutrophil extracellular traps and cardiomyocytes contributes to atrial fibrillation progression显示文摘Atrial fibrillation(AF)is a frequent arrhythmia associated with cardiovascular morbidity and mortality.Neutrophil extracellular traps(NETs)are DNA fragments with cytoplasm proteins released from neutrophils,which are involved in various cardiovascular diseases.To elucidate the role of NETs in AF,we investigated the effect of NETs on AF progression and the secretion of NETs in AF.Results showed that:NETs induced the autophagic apoptosis of cardiomyocytes,and NETs also led to mitochondrial injury by promoting mitochondrial depolarization and ROS production.Ongoing tachy-pacing led to the structural loss of cardiomyocytes and provided potent stimuli to induce NETs secretion from neutrophils.In the meanwhile,increased Ang II in AF facilitated NETs formation through the upregulation of AKT phosphorylation,while it could not directly initiate NETosis as the autophagy was not induced.In vivo,DNase I was administrated to abrogate NETs formation,and AF-related fibrosis was ameliorated as expected.Correspondingly,the duration of the induced AF was reduced.Our study addresses the formation mechanism of NETs in AF and demonstrates the lethal effects of NETs on cardiomyocytes through the induction of mitochondrial injury and autophagic cell death,which comprehensively describes the positive feedback comprised of NETs and stimuli secreted by cardiomyocytes that sustains the progression of AF and AF related fibrosis. | Li He Ruiqi Liu Honghua Yue Xiaoxin Zhang Xiaohui Pan Yutao Sun Jun Shi Guonian Zhu Chaoyi Qin Yingqiang Guo | 2023 | Signal Transduction and Targeted Therapy2023，8，8： | 1 |
| 9 | SZ-5 Cabin’s Height Changes during Three Super-storms in 2003显示文摘In this work,the daily height variations of SZ-5(Shenzhou-5) cabin from 22 October to 28 November in 2003 are analyzed,which includes the period of the Halloween Storm and the Great November Storm.The significant orbital decays have been observed at the end of October and in late November due to the great solar flares and the severe geomagnetic storms.According to the equation of the air-drag-force on a spacecraft and the SZ-5 orbital decay information,the relative daily average thermospheric density changes during the three 2003 super-storms are derived and the results are compared with the Naval Research Laboratory Mass Spectrometer Incoherent Scatter Radar Extended Model(NRLMSISE-00).The results show that the daily average thermospheric density(at the altitude of SZ-5,about 350 km) in storm time enhances to approximately 200% as much as that in the quiet time but the empirical model may somewhat underestimate the average thermospheric density changes and the daily contributions of geomagnetic storms to the density enhancements during these severe space weather events. | HUANG Cong LIU Dandan GUO Jing ZHANG Xiaoxin | 2019 | 空间科学学报2019，39，6： | 0 |
| 10 | 亚高山草甸植物种间花粉传播网络相对于植物-传粉者互作网络年际间更为稳定显示文摘现有研究表明植物-传粉者互作网络结构有较高的年际动态变化。由于传粉者经常在多种植物之间访问,植物-植物的种间花粉传播也可能有较高的动态变化,这对花部特征演化和群落构建有重要的意义。我们连续3年调查了中国西南部一个亚高山草甸群落的植物-传粉者互作网络和植物-植物种间花粉传播网络的年际动态结构。我们发现两种网络的连接都有较高的年际动态,但是植物落置异种花粉构成的年际变化,低于传粉者访问构成的变化,这说明同一对花粉供体和受体植物之间,在年际间可能由不同的共享传粉者传播异种花粉。植物在种间花粉传播网络中的位置,相对植物-传粉者网络中更为稳定。泛化传粉的植物能够输出更多的异种花粉,在种间花粉传播网络中也更重要。我们评估了植物-传粉者互作网络和种间花粉传播网络的年际动态结构,是整合植物-传粉者与植物-植物互作过程的重要一步。 | Qiang Fang Shiyun Guo Tao Zhang Xiaoxin Tang | 2023 | Journal of Plant Ecology2023，16，3： | 0 |
| 11 | The Novel Instance Segmentation Method Based on Multi-Level Features and Joint Attention显示文摘Instance segmentation is an important task in computer vision.In order to enhance the multi-level features expression ability of the segmentation networks,a novel module is proposed in this paper.Firstly,we design a weighted bi-directional feature fusion way by computing the weight distribution function of bi-directional feature pyramid network.Secondly,we propose a joint attention mechanism to effectively filter different levels of feature information by adopting serial and parallel ways to combine the channel attention and spatial attention modules.At the same time,the module uses dynamic convolution to stabilize the calculation speed while improve the 6.7%mean average precision of segmentation.The experiments on the COCO dataset demonstrate that the module can effectively improve the performance of the existing instance segmentation networks. | XU Bowen LU Yinan WU Tieru GUO Xiaoxin | 2023 | Chinese Journal of Electronics2023，32，5： | 0 |
| 12 | Sawtooth and dune auroras simultaneously driven by waves around the plasmapause显示文摘The dune aurora,at a scale of~30 kilometers,was reported recently using ground camera.The small-scale dune aurora occurs on the duskside and exhibits a monochromatic oscillation in the auroral emission,implying fundamental energy conversions.However,whether the dune auroras correspond to atmospheric waves or are associated with magnetospheric dynamics should be determined.This paper reports a dune aurora that occurred during a storm;further,we demonstrate that it was the substructure of the sawtooth aurora that was generated by plasmapause surface waves.Conjugate observations in the magnetospheric source region suggest that the exohiss waves,which are periodically modulated by the plasmapause surface wave-excited ultralow frequency wave,might be responsible for the generation of the dune aurora.Most reported dune aurora events have occurred simultaneously with sawtooth auroras,suggesting that both are plasmapause-driven cross-scale auroral structures. | Fei He ZhongHua Yao BinBin Ni Xing Cao ShengYi Ye RuiLong Guo JinXing Li ZhiPeng Ren XinAn Yue YongLiang Zhang Yong Wei XiaoXin Zhang ZuYin Pu | 2023 | Earth and Planetary Physics2023，7，2： | 0 |
| 13 | Screening of Fermentation Starters for Organic Fertilizer Composted from Chicken Manure显示文摘In order to find fermentation starters that can promote rapid and effective composting of chicken manure,shorten the fermentation period,and improve the compost quality,fermentation starters with different microbial combination ratios(C1,C2,C3,C4 and C5) were designed and fermentation experiment was carried out on these five fermentation starters,commercially available organic fertilizer starter(SS),and chicken manure without inoculating fermentation starter. In the process of the fermentation,the changes in the fermentation temperature,water content and pH value were monitored; the effects of organic manure on the germination rate and growth of rapeseed seeds were measured;viable count,water content,and pH value of prepared fermentation starters were measured; main indicators( organic matter,nitrogen,phosphorus,and potassium) of organic fertilizer generated from fermentation were measured. From the indicators,the formula C3 and C4 were better,in the beginning of fermentation,the temperature rose rapidly,and it reached 40 ℃ in the second day; the water content dropped to below 35% in the 18 th day; the pH value underwent the process of declining-rising-stable,and the overall value showed slight rise,but the change was not great( 0-0. 5). C3 and C4 fermentation products had better effects on the germination and growth of rapeseeds. The germination rate of the rapeseed seeds was 100% and 97. 5% and the bud length was 15. 94 mm and 14. 57 mm,respectively,and the root length was45. 97 mm and 39. 44 mm,respectively. The content of organic matter in fermented organic manure was 86. 62% and 85. 17% respectively,and the total content of nitrogen,phosphorus and potassium was 8. 85% and 8. 22% respectively,and the pH was 7. 5 and 8. 0 respectively.All of these complied with the industry standard NY525-2012( organic matter ≥ 45%,and nitrogen,phosphorus,and potassium ≥ 5%,pH 5. 5-8. 5). The fermentation of fresh chicken manure was completed within 20 days,conforming to the requirements of large-scale organic fertilizer production factory for composting chicken manure into organic fertilizer. | Jifeng CHEN Lishen SHI Hongyuan LIU Jie YANG Ruiliang GUO Dong CHEN Xiaoxin JIANG Yuxiang LIU | 2017 | Asian Agricultural Research2017，9，4： | 0 |
| 14 | Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha显示文摘Bio-manufacturing via microbial cell factory requires large promoter library for fine-tuned metabolic engi-neering.Ogataea polymorpha,one of the methylotrophic yeasts,possesses advantages in broad substrate spec-trum,thermal-tolerance,and capacity to achieve high-density fermentation.However,a limited number of available promoters hinders the engineering of O.polymorpha for bio-productions.Here,we systematically characterized native promoters in O.polymorpha by both GFP fluorescence and fatty alcohol biosynthesis.Ten constitutive promoters(P_(PDH),P_(PYK),P_(FBA),P_(PGM),P_(GLK),P_(TRI),P(GPI),P_(ADH1),P_(TEF1) and P_(GCW14))were obtained with the activity range of 13%–130% of the common promoter P_(GAP)(the promoter of glyceraldehyde-3-phosphate de-hydrogenase),among which P_(PDH) and P_(GCW14) were further verified by biosynthesis of fatty alcohol.Furthermore,the inducible promoters,including ethanol-induced P_(ICL1),rhamnose-induced P_(LRA3) and P_( LRA4),and a bidirectional promoter(P_(Mal)-P_(Per))that is strongly induced by sucrose,further expanded the promoter toolbox in O.polymorpha.Finally,a series of hybrid promoters were constructed via engineering upstream activation sequence(UAS),which increased the activity of native promoter P LRA3 by 4.7–10.4 times without obvious leakage expression.Therefore,this study provided a group of constitutive,inducible,and hybrid promoters for metabolic engineering of O.polymorpha,and also a feasible strategy for rationally regulating the promoter strength. | Chunxiao Yan Wei Yu Xiaoxin Zhai Lun Yao Xiaoyu Guo Jiaoqi Gao Yongjin J.Zhou | 2022 | Synthetic and Systems Biotechnology2022，7，1： | 0 |
| 15 | A nursing study on five‑animal frolics in improving anxiety and depression of inpatients显示文摘Objective:The objective is to investigate the effect of five‑animal frolics on anxiety and depression of hospitalized inpatients.Materials and Methods:Totally 50 inpatients from departments of Internal Medicine,Surgery and General Medicine with hospital admission date between January 2019 and July 2020 were included.All patients exercise five‑animal frolics under the professional guidance of the nurse in charge.The Hospital Anxiety and Depression Scale(HADS)was used to assess the conditions of anxiety and depression of patients before and after taking five‑animal frolics exercise.Results:The overall score of anxiety patients was significantly lower after five‑animal frolics exercise than before[6.0(5.0,8.0)vs.10.0(8.0,12.0),Z=‑5.466,P<0.001];the overall depression score of patients was significantly lower after five‑animal frolics exercise than before[6.5(4.0,8.0)vs.10.0(8.0,14.0),Z=‑5.175,P<0.001].There were 26(52.0%)very effective cases after exercise,16(32.0%)effective cases,8(16.0%)invalid cases,and the effective rate was 84.0%Conclusion:Taking five‑animal frolics exercise can improve anxiety and depression of inpatients. | Xiaoxin LI Xu WANG Fang REN Jinyu GUO Shufen ZHANG Ling TANG | 2021 | Journal of Integrative Nursing2021，3，1： | 0 |
| 16 | Progress in the research on organic piezoelectric catalysts for dye decomposition显示文摘Organic contaminants have posed a direct and substantial risk to human wellness and the environment.In recent years,piezo-electric catalysis has evolved as a novel and effective method for decomposing these contaminants.Although piezoelectric materials offer a wide range of options,most related studies thus far have focused on inorganic materials and have paid little attention to organic materi-als.Organic materials have advantages,such as being lightweight,inexpensive,and easy to process,over inorganic materials.Therefore,this paper provides a comprehensive review of the progress made in the research on piezoelectric catalysis using organic materials,high-lighting their catalytic efficiency in addressing various pollutants.In addition,the applications of organic materials in piezoelectric cata-lysis for water decomposition to produce hydrogen,disinfect bacteria,treat tumors,and reduce carbon dioxide are presented.Finally,fu-ture developmental trends regarding the piezoelectric catalytic potential of organic materials are explored. | Zhaoning Yang Xiaoxin Shu Di Guo Jing Wang Hui Bian Yanmin Jia | 2024 | International Journal of Minerals,Metallurgy and Materials2024，31，2： | 0 |
| 17 | Fast B-spline surface extraction algorithm of seismic volume data on GPU显示文摘In the process of seismic data interpretation,the extraction of a horizon or a fault is generally needed.In this paper we present a fast extraction method.First select some feature points interactively,then reconstruct the surface according to the selected feature points by using B-spline interpolation curve or surface.In order to solve the error-drawing problem appeared in the process of interactive rendering,which is caused by the change of sampling interval as the view point changes,we combine shear-warp and splatting algorithm to render the surface.The rendering of seismic data and specific surface in our work are achieved on GPU platform using CUDA programming language,which make it able to meet the requirements of real-time rendering. | LIN Senqiao CHE Xiangjiu GUO Xiaoxin | 2013 | Computer Aided Drafting,Design and Manufacturing2013，23，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员