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| 1 | Extracellular Matrix Associated Protein CYR61 is Linked to Prostate Cancer Development显示文摘 | Katherine B. D’Antonio Antoun Toubaji Roula Albadine Alison M. Mondul Elizabeth A. Platz George J. Netto Robert H. Getzenberg | 2010 | The Journal of Urology2010，，4： | 1 |
| 2 | Adrenal lymphangioma: clinicopathologic and immunohistochemical characteristics of a rare lesion显示文摘 | Carla L. Ellis Priya Banerjee Erin Carney Rajni Sharma George J. Netto | 2011 | Human Pathology2011，，7： | 1 |
| 3 | Adrenal lymphangioma: clinicopathologic and immunohistochemical characteristics of a rare lesion显示文摘 | Carla L. Ellis Priya Banerjee Erin Carney Rajni Sharma George J. Netto | 2011 | Human Pathology2011，，7： | 1 |
| 4 | A model to predict severe HCV-related disease following liver transplantation显示文摘 | Marina Berenguer Jeffrey Crippin Robert Gish Nathan Bass Alan Bostrom George Netto Judy Alonzo Richard Garcia-Kennedy Jose-Miguel Rayón Teresa L. Wright | 2003 | Hepatology2003，，1： | 1 |
| 5 | Utilization of a TFE3 Break-apart FISH Assay in a Renal Tumor Consultation Service显示文摘 | Whitney M. Green Raluca Yonescu Laura Morsberger Kerry Morris George J. Netto Jonathan I. Epstein Peter B. Illei Mohamad Allaf Marc Ladanyi Constance A. Griffin Pedram Argani | 2013 | The American Journal of Surgical Pathology2013，，8： | 1 |
| 6 | Liver transplant-associated graft-versus-host disease显示文摘 | Douglas M. Smith Edward Agura George Netto Robert Collins Marlon Levy Robert Goldstein Laura Christensen Judy Baker Basel Altrabulsi Lori Osowski Jeff McCormack Lisa Fichtel D. Brian Dawson Rana Domiati-Saad Marvin Stone Goran Klintmalm | 2003 | Transplantation2003，，1： | 1 |
| 7 | Liver transplant-associated graft-versus-host disease显示文摘 | Douglas M. Smith Edward Agura George Netto Robert Collins Marlon Levy Robert Goldstein Laura Christensen Judy Baker Basel Altrabulsi Lori Osowski Jeff McCormack Lisa Fichtel D. Brian Dawson Rana Domiati-Saad Marvin Stone Goran Klintmalm | 2003 | Transplantation2003，，1： | 1 |
| 8 | Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid显示文摘 | Abhinav Sidana Muwen Wang Shabana Shabbeer Wasim H. Chowdhury George Netto Shawn E. Lupold Michael Carducci Ronald Rodriguez Eric W. Lam | 2012 | <journal-title>Journal of Biomedicine and Biotechnology2012，，： | 1 |
| 9 | A modified clinicopathological tumor staging system for survival prediction of patients with penile cancer显示文摘Background:The 8th American Joint Committee on Cancer tumor-node-metastasis(AJCC-TNM)staging system is based on a few retrospective single-center studies.We aimed to test the prognostic validity of the staging system and to determine whether a modified clinicopathological tumor staging system that includes lymphovascular emboliza-tion could increase the accuracy of prognostic prediction for patients with stage T2-3 penile cancer.Methods:A training cohort of 411 patients who were treated at 2 centers in China and Brazil between 2000 and 2015 were staged according to the 8th AJCC-TNM staging system.The internal validation was analyzed by bootstrap-corrected C-indexes(resampled 1000 times).Data from 436 patients who were treated at 15 centers over four conti-nents were used for external validation.Results:A survivorship overlap was observed between T2 and T3 patients(P=0.587)classified according to the 8th AJCC-TNM staging system.Lymphovascular embolization was a significant prognostic factor for metastasis and survival(all P<0.001).Based on the multivariate analysis,only lymphovascular embolization showed a significant influ-ence on cancer-specific survival(CSS)(hazard ratio=1.587,95%confidence interval=1.253-2.011;P=0.001).T2 and T3 patients with lymphovascular embolization showed significantly shorter CSS than did those without lymphovascu-lar embolization(P<0.001).Therefore,a modified clinicopathological staging system was proposed,with the T2 and T3 categories of the 8th AJCC-TNM staging system being subdivided into two new categories as follows:t2 tumors invade the corpus spongiosum and/or corpora cavernosa and/or urethra without lymphovascular invasion,and t3 tumors invade the corpus spongiosum and/or corpora cavernosa and/or urethra with lymphovascular invasion.The modified staging system involving lymphovascular embolization showed improved prognostic stratification with significant differences in CSS among all categories(all P<0.005)and exhibited higher accuracy in predicting patient prognoses than did the 8th AJCC-TNM staging system(C-index,0.739 vs.0.696).These results were confirmed in the external validation cohort.Conclusions:T2-3 penile cancers are heterogeneous,and a modified clinicopathological staging system that incorporates lymphovascular embolization may better predict the prognosis of patients with penile cancer than does the 8th AJCC-TNM staging system. | Zai-Shang Li Antonio Augusto Ornellas Christian Schwentner Xiang Li Alcides Chaux Georges Netto Arthur LBurnett Yong Tang JiunHung Geng Kai Yao Xiao-Feng Chen Bin Wang Hong Liao Nan Liu Peng Chen Yong-Hong Lei Qi-Wu Mi Hui-Lan Rao Ying-Ming Xiao Qi-Lin Wang Zi-Ke Qin Zhuo-Wei Liu Yong-Hong Li Zi-Jun Zou Jun-Hang Luo Hui Li Hui Han Fang-Jian Zhou | 2018 | Cancer Communications2018，38，1： | 0 |
| 10 | 阴茎癌改良临床病理肿瘤分期预后意义分析显示文摘背景与目的第8版美国癌症联合会-TNM(American Joint Committee on Cancer tumor–node–metastasis,AJCC-TNM)分期基于的是一些回顾性单中心研究。本研究旨在分析分期的预后价值,并探讨加入脉管癌栓的改良的临床病理肿瘤分期能否提高对T2–3期阴茎癌患者预后预测的准确性。方法根据第8版AJCC-TNM分期对2000年至2015年在中国和巴西2个中心接受治疗的411例患者所组成的训练队列进行分期。采用C-indexes一致性系数进行预测模型的评估,Bbootstrap再抽样法(1000次)进行模型验证。采用来自4个大洲15个中心接受治疗的436例患者的数据进行外部验证。结果根据第8版AJCC-TNM分期的T2和T3期患者有存活率重叠(P=0.587)。脉管癌栓是转移和生存的重要预后因素(均P <0.001)。多因素分析显示,仅脉管癌栓对癌症特异性生存(cancer-specific survival,CSS)有显著影响(风险比=1.587,95%置信区间=1.253–2.011;P=0.001)。发生脉管癌栓的T2和T3期患者的CSS显著短于无脉管癌栓的患者(P <0.001)。因此,我们提出一种改良的临床病理分期,将第8版AJCC-TNM分期的T2和T3期细分为如下2个新类别:T2期肿瘤侵犯尿道海绵体和/或阴茎海绵体和/或尿道且无淋巴管侵犯;T3期肿瘤侵犯尿道海绵体和/或阴茎海绵体和/或尿道并有淋巴管侵犯。加入脉管癌栓的改良的分期显示出预后分层改善,各组间CSS差异显著(均P <0.005),患者预后预测的准确性高于第8版AJCC-TNM分期(C-index,0.739 vs. 0.696)。以上结果在外部验证队列中得到了确认。结论 T2–3期阴茎癌是异质性的,加入脉管癌栓的改良临床病理分期比第8版AJCC-TNM分期对阴茎癌患者的预后预测能力更强。 | Zai-Shang Li Antonio Augusto Ornellas Christian Schwentner Xiang Li Alcides Chaux Georges Netto Arthur L.Burnett Yong Tang Jiun Hung Geng Kai Yao Xiao-Feng Chen Bin Wang Hong Liao Nan Liu Peng Chen Yong-Hong Lei Qi-Wu Mi Hui-Lan Rao Ying-Ming Xiao Qi-Lin Wang Zi-Ke Qin Zhuo-Wei Liu Yong-Hong Li Zi-Jun Zou Jun-Hang Luo Hui Li Hui Han Fang-Jian Zhou | 2019 | 癌症2019，38，6： | 0 |
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