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| 1 | Medium-and long-term efficacy of ligustrazine plus conventional medication on ischemic stroke: a systematic review and meta-analysis显示文摘OBJECTIVE: To evaluate the mediumto long-term efficacy of ligustrazine plus conventional medicine treating ischemic stroke. METHODS: Randomized controlled trials(RCTs) testing ligustrazine in the treatment of acute ischemic stroke were retrieved from Cochrane Library, PubMed, Excerpta Medica Database, Chinese Medical Journal Database, Chinese Biomedical Database, China National Knowledge Infrastructure Database, and Chinese Clinical Trial Register, and then identified by the inclusive and exclusive criteria. The quality of trials was assessed with the Cochrane Handbook 5.1, a risk of bias assessment tool. RevMan 5.1 was used for meta-analysis.RESULTS: Three RCTs involving 643 patients were included. Compared to conventional medicine treatment alone, ligustrazine plus conventional medicine treatment showed significant difference in reduction of stroke recurrence either at the end of 1-year follow-up [RR=0.42, 95% CI(0.18, 0.94), P< 0.05] or 3-years observation [RR=0.48, 95% CI(0.27, 0.83), P<0.05]. The ligustrazine group also showed higher survival rate [RR=1.67, 95% CI(1.02, 0.2.71), P<0.05] and significantly better effective rate [RR= 1.28, 95% CI(1.10, 1.50), P<0.05] than that of the control group at the end of 1 year visit. Only one trial conducted safety assessment and no adverse events were reported. The methodological quality of all the trials included was generally poor. CONCLUSION: The findings provided evidence that the combination of ligustrazine and conventional medication was mediumand long-term beneficial to the patients suffering ischemic stroke. But more RCTs of high quality are needed to further prove the efficacy and safety of using ligustrazine for ischemic stroke. | Xiaojia Ni Shaonan Liu Xinfeng Guo | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 6 |
| 2 | Reporting quality and effect size comparison in randomized controlled trials of bo's abdominal acupuncture using CONSORT statement and STRICTA显示文摘OBJECTIVE: To evaluate the reporting quality of randomized controlled trials(RCT) that compared Bo's abdominal acupuncture with conventional body acupuncture, and compare the efficacy and safetybetweenthembyperforminga Meta-analysis.METHODS: All RCTs comparing Bo's abdominalacupuncture with conventional body acupuncture were included. English and Chinese databases were searched from their respective inceptions to March 2014. The reporting quality was assessed according to the 'Consolidated Standards of Reporting Trials'(CONSORT) checklist for parallel RCTs and the revised 'Standards for Reporting Interventions in Clinical Trials of Acupuncture'(STRICTA). A Meta-analysis was conducted to synthesize the effect sizes,and publication bias was evaluated by the Egger linear regression test using Stata.RESULTS: Ninety-seven studies were included, of which most lacked adequate reporting information, and 80.4% showed that the efficacy of abdominal acupuncture is superior to conventional body acupuncture, especially for the following diseases:lumbar disc herniation, cervical spondylosis, omarthritis and cervical vertigo, except simple obesity.Effect-sizes were controversial when evaluating different outcomes.CONCLUSION: The international standard CONSORT statement and STRICTA guidelines should be strictly applied when reporting acupuncture RCTs in the future. Abdominal acupuncture appears to be more effective compared with conventional body acupuncture for some diseases. However, further high quality blind RCTs using validated outcomeindexesandstandardreportingarewarranted. | Wen Wanxin Yang Lihong Liu Shaonan Zhong Ying Hu Xiaoyi Huang Xiaowan Guo Xinfeng | 2016 | Journal of Traditional Chinese Medicine2016，36，3： | 5 |
| 3 | Pattern of cerebrovascular atherosclerotic stenosis in older Chinese patients with stroke显示文摘 | Fang Yang Ling Liu Min Li Mingquan Li Qin Yin Ruibing Guo Yun Li Guanghui Chen Renliang Zhang Xinfeng Liu | 2013 | Journal of Clinical Neuroscience2013，，7： | 1 |
| 4 | Effects of porcine circovirus type 2 on expression of mRNA associated with endogenous antigen processing and presentation in pulmonary alveolar macrophages and circulating T lymphocytes in piglets显示文摘 | Jiandong Li Qi Yu Xiaohua Nie Xinfeng Guo Qinye Song Huanrong Li | 2011 | The Veterinary Journal2011，，1： | 1 |
| 5 | Consistency Simulation and Optimization for HPIBM Model in Emergency Decision Making显示文摘 | Daji Ergu Mingshan Zhang Zhili Guo Xinfeng Yang | 2014 | Procedia Computer Science2014，，： | 1 |
| 6 | Sulfur vs. tellurium: the heteroatom effects on the nonfullerene acceptors显示文摘The effect of chalcogen heteroatom variation on donor materials has been systematically investigated. However, this effect on acceptors has rarely been explored. Herein, nonfullerene acceptors BFPSP and BFPTP were reported by simply changing the chalcogen atoms from S to Te. The differences between BFPSP and BFPTP in light absorption, energy levels, excited-state lifetimes, energy loss, charge mobilities, morphology, and photovoltaic properties were systematically investigated to understand the heteroatom effects. More importantly, the electroluminescence spectra, external quantum efficiency of photovoltaics and TDDFTcalculations revealed that the triplet excited state(T1) in energy of BFPTP equals to the charge transfer(CT) state in PBDBT:BFPTP, which allows T1 excitons, generated by intersystem crossing, to split into free charges to contribute to the efficiency.This contribution provides a strategy for tuning the photophysical properties of nonfullerene acceptors and designing high performance triplet materials for OSCs. | Lei Yang Linqing Qin Yunxiao Xu Huotian Zhang Lei Lv Kepeng Chen Xinyu Sui Yangguang Zhong Yuan Guo Feng Gao Jianzhang Zhao Yuhao Li Xinfeng Liu Yuanping Yi Xinhui Lu Aidong Peng Hui Huang | 2019 | Science China Chemistry2019，62，7： | 1 |
| 7 | Dynamic friction energy dissipation and enhanced contrast in high frequency bimodal atomic force microscopy显示文摘Dynamic friction occurs not only between two contact objects sliding against each other,but also between two relative sliding surfaces several nanometres apart.Many emerging micro-and nano-mechanical systems that promise new applications in sensors or information technology may suffer or benefit from noncontact friction.Herein we demonstrate the distance-dependent friction energy dissipation between the tip and the heterogeneous polymers by the bimodal atomic force microscopy(AFM)method driving the second order flexural and the first order torsional vibration simultaneously.The pull-in problem caused by the attractive force is avoided,and the friction dissipation can be imaged near the surface.The friction dissipation coefficient concept is proposed and three different contact states are determined from phase and energy dissipation curves.Image contrast is enhanced in the intermediate setpoint region.The work offers an effective method for directly detecting the friction dissipation and high resolution images,which overcomes the disadvantages of existing methods such as contact mode AFM or other contact friction and wear measuring instruments. | Xinfeng TAN Dan GUO Jianbin LUO | 2022 | Friction2022，10，5： | 1 |
| 8 | Active control of friction realized by vibrational excitation:Numerical simulation based on the Prandtl-Tomlinson model and molecular dynamics显示文摘Superlubricity and active friction control have been extensively researched in order to reduce the consumption of fossil energy,the failure of moving parts,and the waste of materials.The vibration-induced superlubricity(VIS)presents a promising solution for friction reduction since it does not require high-standard environment.However,the mechanism underlying the VIS remains unclear since the atomic-scale information in a buried interface is unavailable to experimental methods.In this paper,the mechanism of VIS was examined via numerical calculation based on the Prandtl-Tomlinson(PT)model and molecular dynamics(MD)simulations.The results revealed that the pushing effect of stick-slip is one of the direct sources of friction reduction ability under vibrational excitation,which was affected by the response amplitude,frequency,and the trace of the tip.Moreover,the proportion of this pushing effect could be modulated by changing the phase difference when applying coupled vibrational excitation in x-and z-axis.This results in a significant change in friction reduction ability with phase.By this way,active friction control from the stick-slip to superlubricity can be achieved conveniently. | Xiao MA Xinfeng TAN Dan GUO Shizhu WEN | 2023 | Friction2023，11，7： | 0 |
| 9 | Letters for 'Prospects for the future of clinical efficacy evaluation of traditional Chinese Medicine—Emphasis on original theory and clinical practice'显示文摘Editorial Note:On January 1,2020,we published an online comment,titled“Prospects for the future of clinical efficacy evaluation of traditional Chinese medicine——Emphasis on original theory and clinical practice”,which focuses on the evaluation of traditional Chinese medicine.After the article was published,it attracted the attention of some scholars,who discussed with the editorial department by letters.The relevant letters are organized as follows for further communication and discussion by readers. | Yaolong Chen Kehu Yang Xinfeng Guo Darong Wu Ling Zhao Bo Li | 2020 | TMR Modern Herbal Medicine2020，3，1： | 0 |
| 10 | Comparative analysis of frictional behavior and mechanism of molybdenum ditelluride with different structures显示文摘Two-dimensional(2D)transition metal dichalcogenides(TMDCs)have layered structures with excellent tribological properties.Since the energy difference between hexagonal-molybdenum ditelluride(2H-MoTe_(2))and distorted octahedral-molybdenum ditelluride(1T′-MoTe_(2))is very small among the transition metal dichalcogenides(TMDCs),MoTe_(2) becomes one of the most promising candidates for phase engineering.In our experiment,we found that the friction force and friction coefficient(COF)of 2H-MoTe_(2) were an order of magnitude smaller than those of 1T′-MoTe_(2) by the atomic force microscope(AFM)experiments.The friction difference between 1T′-MoTe_(2) and 2H-MoTe_(2) was further verified in molecular dynamics(MD)simulations.The density functional theory(DFT)calculations suggest that the friction contrast is related to the difference in sliding energy barrier of the potential energy surface(PES)for a tip sliding across the surface.The PES obtained from the DFT calculation indicates that the maximum energy barrier and the minimum energy path(MEP)energy barrier of 2H-MoTe_(2) are both smaller than those of 1T′-MoTe_(2),which means that less energy needs to be dissipated during the sliding process.The difference in energy barrier of the PES could be ascribed to its larger interlayer spacing and weaker Mo–Te interatomic interactions within the layers of 2H-MoTe_(2) than those of 1T′-MoTe_(2).The obvious friction difference between 1T′-MoTe_(2) and 2H-MoTe_(2) not only provides a new non-destructive means to detect the phase transition by the AFM,but also provides a possibility to tune friction by controlling the phase transition,which has the potential to be applied in extreme environments such as space lubrication. | Lina ZHANG Xinfeng TAN Jianguo JIAO Dan GUO Jianbin LUO | 2024 | Friction2024，12，1： | 0 |
| 11 | Extensive gene flow in secondary sympatry after allopatric speciation显示文摘In the conventional view,species are separate gene pools delineated by reproductive isolation(RI).In an alternative view,species may also be delineated by a small set of’speciation genes’without full RI,a view that has gained broad acceptance.A recent survey,however,suggested that the extensive literature on’speciation with gene flow’is mostly(if not all)about exchanges in the early stages of speciation.There is no definitive evidence that the observed gene flow actually happened after speciation is completed.Here,we wish to know whether’good species’(defined by the’secondary sympatry’test)do continue to exchange genes and,importantly,under what conditions such exchanges can be observed.De novo whole-genome assembly and re-sequencing of individuals across the range of two closely related mangrove species(Rhizophora mucronata and R.stylosa)reveal the genomes to be well delineated in allopatry.They became sympatric in northeastern Australia but remain distinct species.Nevertheless,their genomes harbor~4000-10000 introgression blocks averaging only about 3-4 Kb.These fine-grained introgressions indicate continual gene flow long after speciation as non-introgressable’genomic islets,’~1.4 Kb in size,often harbor diverging genes of flower or gamete development.The fine-grained introgression in secondary sympatry may help settle the debate about sympatric vs.micro-allopatric speciation.In conclusion,true’good species’may often continue to exchange genes but the opportunity for detection is highly constrained. | Xinfeng Wang Ziwen He Zixiao Guo Ming Yang Shaohua Xu Qipian Chen Shao Shao Sen Li Cairong Zhong Norman C.Duke Suhua Shi | 2022 | National Science Review2022，9，12： | 0 |
| 12 | Interlayer friction behavior of molybdenum ditelluride with different structures显示文摘The interlayer friction behavior of two-dimensional transition metal dichalcogenides(TMDCs)as crucial solid lubricants has attracted extensive attention in the field of tribology.In this study,the interlayer friction is measured by laterally pushing the MoTe_(2)powder on the MoTe_(2)substrate with the atomic force microscope(AFM)tip,and density functional theory(DFT)simulations are used to rationalize the experimental results.The experimental results indicate that the friction coefficient of the 1T'-MoTe_(2)/1T'-MoTe_(2)interface is 2.025×10^(−4),which is lower than that of the 2H-MoTe_(2)/2H-MoTe_(2)interface(3.086×10^(−4)),while the friction coefficient of the 1T'-MoTe_(2)/2H-MoTe_(2)interface is the lowest at 6.875×10^(−5).The lower interfacial friction of 1T'-MoTe_(2)/1T'-MoTe_(2)compared to 2H-MoTe_(2)/2H-MoTe_(2)interface can be explained by considering the relative magnitudes of the ideal average shear strengths and maximum shear strengths based on the interlayer potential energy.Additionally,the smallest interlayer friction observed at the 1T'-MoTe_(2)/2H-MoTe_(2)heterojunction is attributed to the weak interlayer electrostatic interaction and reduction in potential energy corrugation caused by the incommensurate contact.This work suggests that MoTe_(2)has comparable interlayer friction properties to MoS_(2)and is expected to reduce interlayer friction in the future by inducing the 2H-1T'phase transition. | Lina Zhang Xinfeng Tan Jianguo Jiao Dan Guo Jianbin Luo | 2023 | Nano Research2023，16，8： | 0 |
| 13 | Evidence for Octupole Correlations in ^(117)Xe显示文摘Evidence for Octupole Correlations in ￣(117)XeEvidenceforOctupoleCorrelationsin￣(117)XeLiuZhong;SunXiangfu;ZhouXiaohong;LeiXi... | Liu Zhong Sun Xiangfu Zhou Xiaohong Lei Xiangguo Guo YingXiang Chen Xinfeng Jin Hanjuan Zhang Yuhu Luo YiXiao Wen Shuxian Yuan Guanjun Yang Chunxiang Li Guangsheng and Liu Xiangan | 1995 | IMP & HIRFL Annual Report1995，，0： | 0 |
| 14 | Lifetimes Measurement of 11/2- and 7/2-States in ^(117)Xe显示文摘Lifetimes Measurement of 11/2- and 7/2-States in^(117)XeLifetimesMeasurementof11/2-and7/2-Statesin^(117)Xe￥LiuZhong;SunXiangfu... | Liu Zhong Sun Xiangfu Lei Xiangguo Guo YingXiang Cheng Xinfeng Zhou Xiaohong Zhang Yuhu Jin Hanjuan Luo Yixiao Wen Shuxian Yuan Guanjun Liu Xiangan and Yang Chunxiang | 1995 | IMP & HIRFL Annual Report1995，，0： | 0 |
| 15 | Observation of Noncollective Excitation in ^(117)Xe显示文摘Observation of Noncollective Excitation in^(117)XeObservationofNoncollectiveExcitationin^(117)Xe￥LiuZhong;SunXiangfu;ZhouXiaoh... | Liu Zhong Sun Xiangfu Zhou Xiaohong Let Xiangguo Guo Yingkiang Zhang Yuhu Jin Hanjuan Chen Xinfeng Luo Yixiao Wen Shuxian Yuan Guanjun Yang Chunxiang Li Guangsheng Liu Xiangan Luo Wendong Chen Yongshou | 1995 | IMP & HIRFL Annual Report1995，，0： | 0 |
| 16 | Progress in Lifetime Measurement with Plunger显示文摘Progress in Lifetime Measurement with Plunger￥ChenXinfeng;SunXiangfu;GuoYingxiang;LiuZhong;ZhouXiaohong;LetXiangguo;JinHanjua... | Chen Xinfeng Sun Xiangfu Guo Yingxiang Liu Zhong Zhou Xiaohong Let Xiangguo Jin Hanjuan and Luo Yixiao | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
| 17 | Identification of γ-rays in ^(198)Bi显示文摘Identification of γ-rays in ^(198)Bi￥ZhouXiaohong;SunXiangfu;LetXiangguo;ChenXinfeng;LiuZhong;ZhangYuhu;JinHanjuan;GuoYingxia?.. | Zhou Xiaohong Sun Xiangfu Let Xiangguo Chen Xinfeng Liu Zhong Zhang Yuhu Jin Hanjuan Guo Yingxiang Luo Yiniao Wen Shuxian Yuan Guanjun Li Guangsheng and Yang Chunxian(Departemt of Nuclear Physics,CIAE,Beijing.) | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
| 18 | Determination of an Isomeric State in ^(198)Bi显示文摘Determination of an Isomeric State in ^(198)Bi￥ZhouXiaohong;SunXiangfu;LetXiangguo;ChenXinfeng;LiuZhong;ZhangYuhu;JinHanjuan;?.. | Zhou Xiaohong Sun Xiangfu Let Xiangguo Chen Xinfeng Liu Zhong Zhang Yuhu Jin Hanjuan Guo Yingxiang Luo Yisiao Wen Shuxian Yuan Guanjun Li Guangsheng and Yang Chunxian(Department of Nuclear Physics,CLAE,Beijing.) | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
| 19 | Systematic review on the adverse reactions of oral administration of Indigo Naturalis and its preparations显示文摘Objective:This article systematically analyses the effects of adverse drug events/adverse drug reactions(ADEs/ADRs)of oral Indigo Naturalis(Qingdai)preparations in order to provide references for its rational clinical application.Methods:All clinical studies reporting ADE/ADR related to the oral administration of Qingdai preparations were searched through electronic databases,including PubMed,the Cochrane Library,Embase,China National Knowledge Infrastructure(CNKI),China Biology Medicine disc(CBM),VIP Information Chinese Journal Service Platform(VIP),and Wanfang database,from inception to September 27,2020.Information were extracted from these literatures,including primary disease,type of adverse reactions,dose,treatment,outcomes and so on.Incidence of ADE/ADR was estimated,as well as distribution of primary diseases and victim organs and systems were analyzed.Results:A total of 682 articles were included,with 651 clinical population studies and 31 case reports.Among them,604 detailed ADR/AE involving 33459 patients using oral Qingdai preparations,and a total of 5061 cases were found to present adverse events,including 2827 cases of digestive system(abdominal pain,diarrhea,etc.),469 cases of blood system damage(thrombocytopenia,leukopenia,anemia,etc.),313 cases of liver damage(abnormal liver function,liver toxicity,elevated liver enzymes,etc.),327 cases of nervous system reactions(headache,dizziness,poor sleep,etc.)and 1186 cases of other systems and organs.Severe adverse events(SAEs)mainly were liver damage,and could be relived after symptomatic treatment.Conclusion:From the systematic information retrieval and analysis,it is found that oral Qingdai preparations application may clinically cause ADEs/ADRs in terms of gastrointestinal tract and liver damage.Therefore,when using oral Qingdai preparations,liver and stomach protection should be done.At the same time,pay close attention to various biochemical indicators and the patient's drug response during the treatment process,and,if necessary,deal with it in time so as not to deteriorate the condition.Moreover,active surveillance system should be conducted to monitor ADE/ADR,so as to establish a clearer causal relationship between the drug and the adverse event. | Xueyi Deng Rui Lan Qianwen Xie Jingmin Xiao Jiaqi Lai Jing Chen Yihan He Shaonan Liu Lihong Yang Xinfeng Guo | 2021 | TMR Modern Herbal Medicine2021，4，1： | 0 |
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