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| 1 | Coordinated regulation of apical hook development by gibberellins and ethylene in etiolated Arabidopsis seedlings显示文摘当在土壤发芽时,当通过土壤耸出时,黑暗成年的 Arabidopsis 幼苗开发一个顶端的钩,它保护子叶和顶端的 meristematic 纸巾。几荷尔蒙被报导清楚地调制这个过程。以前的研究证明了乙烯和赤霉素(气体) 并列地调整钩发展,尽管内在的分子的机制大部分是未知的。当 paclobutrazol 镇压了时,这里,我们显示出提高的那 GA 3 ethylene-overexpression 和 EIN3-overexpression (EIN3ox ) 导致了钩弯曲,并且 della 异种展出了夸大的钩弯曲,它要求了发信号的未经触动的乙烯小径。基因学习表明那提高 GA 的钩开发依赖于无钩 1 (HLS1 ) ,调停的一个中央管理者多重发信号小径的输入在顶端的钩开发期间。我们进一步发现那 GA 3 导致(并且 DELLA 蛋白质镇压了) 在乙烯感觉迟钝的 3/EIN3-LIKE 的 HLS1 表示 1 (EIN3/EIL1 ) 依赖举止, EIN3/EIL1 由此激活 HLS1 抄写由对它的倡导者直接有约束力。另外, DELLA 蛋白质被发现与 EIN3/EIL1 的 DNA 有约束力的领域交往并且镇压 EIN3/EIL1-regulated HLS1 表示。有 naphthylphthalamic 酸的处理,一个极的植物生长素运输禁止者,镇压 EIN3ox 线的组成地夸大的钩弯曲和 della 异种,支持那植物生长素在钩开发乙烯和 GA 小径下游地工作。一起拿,我们的结果作为联系 DELLA 的抄写因素的一个新类识别 EIN3/EIL1 并且证明 GA 由经由 EIN3/EIL1 函数的 derepression 导致 HLS1 的表达式部分与乙烯在合作支持顶端的钩形成。 | Fengying An Xing Zhang Ziqiang Zhu Yusi Ji Wenrong He Zhiqiang Jiang Mingzhe Li Hongwei Guo | 2012 | Cell Research2012，22，5： | 34 |
| 2 | Trust Access Authentication in Vehicular Network Based on Blockchain显示文摘Data sharing and privacy securing present extensive opportunities and challenges in vehicular network.This paper introducestrust access authentication scheme’as a mechanism to achieve real-time monitoring and promote collaborative sharing for vehicles.Blockchain,which can provide secure authentication and protected privacy,is a crucial technology.However,traditional cloud computing performs poorly in supplying low-latency and fast-response services for moving vehicles.In this situation,edge computing enabled Blockchain network appeals to be a promising method,where moving vehicles can access storage or computing resource and get authenticated from Blockchain edge nodes directly.In this paper,a hierarchical architecture is proposed consist of vehicular network layer,Blockchain edge layer and Blockchain network layer.Through a authentication mechanism adopting digital signature algorithm,it achieves trusted authentication and ensures valid verification.Moreover,a caching scheme based on many-to-many matching is proposed to minimize average delivery delay of vehicles.Simulation results prove that the proposed caching scheme has a better performance than existing schemes based on central-ized model or edge caching strategy in terms of hit ratio and average delay. | Shaoyong Guo Xing Hu Ziqiang Zhou Xinyan Wang Feng Qi Lifang Gao | 2019 | China Communications2019，16，6： | 10 |
| 3 | Genetic Basis of Ethylene Perception and Signal Transduction in Arabidopsis显示文摘Ethylene is a simple gaseous hormone in plants. It plays important roles in plant development and stress tolerance. In the presence of ethylene treatment, all ethylene receptors are in an activated form, which can physically interact with CTR1 and consequently recruit CTR1 protein to endoplasmic reticulum membrane to activate it. Activated CTR1 suppresses the downstream signal transduction by an unknown mechanism. Upon binding to its receptors, ethylene will inactivate the receptor/CTR1 module and in turn alleviate their inhibitory effect on two positive regulators acting downstream of CTR1: EIN2 and EIN3. Genetic study reveals that EIN2 is an essential component in the ethylene signaling pathway but its biochemical function remains a mystery. EIN3 is a plant-specific transcription factor and its protein abundance in the nucleus is rapidly induced upon ethylene treatment. In the absence of ethylene signal, EIN3 protein is degraded by an SCF complex containing one of the two F-box proteins EBF1/EBF2 in a 26S proteasome-dependent manner. EIN3 can bind to the promoter sequences of a number of downstream components, such as ERFs, which in turn bind to a GCC box, a cis-element found in many ethylene-regulated defense genes. Ethylene has been shown to also regulate many other hormones' signaling pathways including auxin, abscisic acid and jasmonic acid, implying the existence of complicated signaling networks in the growth, development and defense responses of various plants. | Ziqiang Zhu Hongwei Guo | 2008 | Journal of Integrative Plant Biology2008，50，7： | 9 |
| 4 | Effect of treatment course of comprehensive intervention with Traditional Chinese Medicine on mortality of acquired immunodeficiency syndrome patients treated with combined antiretroviral therapy显示文摘OBJECTIVE:To investigate the effect of a treatment course of comprehensive intervention with Traditional Chinese Medicine(TCM) on the mortality of patients with acquired immunodeficiency syndrome(AIDS) treated with combined antiretroviral therapy(c ART).METHODS:AIDS patients who had taken c ART in a national TCM human immunodeficiency virus treatment trial program(NTCMTP) before 2009 were enrolled in this study and followed for 36 months from November 2009.Patients enrolled in the NTCMTP in 2004 were taken as the first group,those enrolled in 2006 as the second group,and those enrolled in 2009 as the third group.Cumulative survival rates were calculated by the life table method.Survival curves for subgroups were compared by the log-rank test.Hazard ratios were calculated with a Cox proportional hazards model.RESULTS:A total of 1443 AIDS patients were followed for 3 years(4198 person-years).During this period,91(6.3%) patients died and 13(0.9%) were lost to follow-up.The total mortality rate was 2.17/100 person-years.The mortality rate of patients enrolled in the NTCMTP in 2004 was 1.49/100 person-years,which was lower than that of patients enrolled in 2006(2.23/100 person-years) and 2009(3.48/100 person-years).After adjusting for other factors,a shorter time of treatment with TCM,male sex,older age,lower CD4 + T-cell counts,and long-term treatment with c ART were risk factors of mortality.CONCLUSION:Long-term treatment with TCM decreased the mortality risk of AIDS patients.Factors such as being male,older age,CD4+ T-cell counts,and time of treatment with TCM and c ART were correlated with mortality. | Guo Huijun Wang Jian Li Zhengwei Jiang Ziqiang Xu Qianlei Xu Liran | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 9 |
| 5 | Survival of people living with HIV after treatment with Traditional Chinese Medicine in Henan province of China: a retrospective cohortstudy显示文摘OBJECTIVE: To provide survival estimates of people living with human immunodeficiency virus(PLHIV) after treatment with Traditional Chinese Medicine(TCM) in rural China, to identify the prognostic factors at enrollment, and to explore the effectiveness of TCM intreating PLHIV.METHODS: PLHIV who enrolled in national TCM HIV treatment trial program in October 2004 were analyzed in this study and followed up to October 2010. Survival time was estimated by the Kaplan-Meier curve and hazard ratios, and identifying prognostic factors were computed through Cox proportional hazard models.RESULTS:A total of 1666 PLHIV were included with 102 591 person-months of follow-up. Overall, 312(18.7%) patients died. The total mortality rate over the study period was 3.6 per 100 person-years,which was lower than the worldwide rate. The cumulative survival rate was 95.9% at 1 year[95% confidence interval(CI)(94.8-96.8)] and 80.4% at 6years [95% CI(78.4-82.3)]. Elevated death risks emerged among males, older individuals, and thosewithlowerCD4+T-cellcounts.CONCLUSION: TCM could increase survival and lengthen the life span of PLHIV in Henan province of China, as shown by our retrospective cohort study. Factors such as sex, age, education, and CD4+ T-cell counts correlated to survival. However,retrospective cohorts bias the data, so more prospective studies should be performed to confirm our primary results. | Yantao Jin Zhibin Liu Xiumin Chen Xin Wang Dan Wang Ziqiang Jiang Ying Liu Jian Wang Wen Zou Huijun Guo Liran Xu | 2014 | Journal of Traditional Chinese Medicine2014，34，4： | 8 |
| 6 | Reliability and validity of dermatology life quality index: assessment of quality of life in human immunodeficiency virus/acquired immunodeficiency syndrome patients with pruritic papular eruption显示文摘OBJECTIVE: To test the reliability and validity of dermatology life quality index(DLQI) in simplified Chinese language by assessing the quality of life(QoL) in HIV(human immunodeficiency virus)/AIDS(Acquired immunodeficiency syndrome) patients with pruritic papular eruption(PPE). METHODS: A study of simplified-Chinese-versiond from10 questions with the principal component analysis and the contribution rate of the 3 common factors was 59.95%. CONCLUSION: The simplified-Chinese-version DIQL is an acceptable and valid scale for HIV/AIDS patients with PPE. It can be used to evaluate the QoL of HIV/AIDS patients with PPE in China. | Zhibin Liu Zheng Xie Li Zhang Yantao Jin Huijun Guo Ziqiang Jiang Xiumin Chen Jun Yuan | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 5 |
| 7 | Laboratory-based Surveillance and Clinical Profile of Sporadic HEV Infection in Shanghai,China显示文摘The study aimed to describe the epidemiological,virological and clinical features of sporadic HEV infection in eastern China.A total of 6112 patient sera were tested for anti-HEV IgG or anti-HEV IgM during one consecutive year(between August 2018 and July 2019).HEV RNA presence was evaluated by RT-PCR and HEV sequences were phylogenetically analyzed.Clinical features of confirmed HEV-infected patients were delineated.The sero-positivity rate of anti-HEV IgG maintained stable around 40%,while an obvious winter spike of anti-HEV IgM prevalence was observed.A total of 111 patients were confirmed of HEV viremia by molecular diagnosis.Subtype 4d was predominant.Phylogenetic analyses suggest that certain strains circulate across species and around the country.Subjects with confirmed current HEV infection had a high median age(58 years)and males were predominant(62.2%).Most patients presented with jaundice(75.7%)and anorexia(68.0%).Significantly elevated levels of liver enzymes and bilirubin were observed.Remarkably,the baseline bilirubin level was positively correlated with illness severity.Pre-existing HBV carriage may deteriorate illness.The clinical burden caused by locally acquired HEV infection is increasing.Surveillance should be enforced especially during the transition period from winter to spring.Patients with higher level of bilirubin at disease onset had slower recovery from HEV infection. | Jie Lu Qing Li Jiayuan Jiang Ziqiang Li Peiyun Wang Zike Sheng Rongtao Lai Huijuan Zhou Wei Cai Hui Wang Qing Guo Honglian Gui Qing Xie | 2021 | Virologica Sinica2021，36，4： | 4 |
| 8 | Mobility in China,2020:a tale of four phases显示文摘2020 was an unprecedented year;with rapid and drastic changes in human mobility due to the COVID-19 pandemic.To understand the variation in commuting patterns among the Chinese population across stable and unstable periods,we used nationwide mobility data from 318 million mobile phone users in China to examine the extreme fluctuations of population movements in 2020,ranging from the Lunar New Year travel season(chunyun),to the exceptional calm of COVID-19 lockdown,and then to the recovery period.We observed that cross-city movements;which increased substantially in chunyun and then dropped sharply during the lockdown,are primarily dependent on travel distance and the socio-economic development of cities.Following the Lunar New Year holiday,national mobility remained low until mid-February,and COVID-19 interventions delayed more than 72.89 million people returning to large cities.Mobility network analysis revealed clusters of highly connected cities,conforming to the social-economic division of urban agglomerations in China.While the mass migration back to large cities was delayed,smaller cities connected more densely to form new clusters.During the recovery period after travel restrictions were lifted,the netflows of over 55%city pairs reversed in direction compared to before the lockdown.These findings offer the most comprehensive picture of Chinese mobility at fine resolution across various scenarios in China and are of critical importance for decision making regarding future public-health-emergency response,transportation planning and regional economic development,among others. | Suoyi Tan Shengjie Lai Fan Fang Ziqiang Cao Bin Sai Bing Song Bitao Dai Shuhui Guo Chuchu Liu Mengsi Cai Tong Wang Mengning Wang Jiaxu Li Saran Chen Shuo Qin Jessica R.Floyd Zhidong Cao Jing Tan Xin Sun Tao Zhou Wei Zhang Andrew J.Tatem Petter Holme Xiaohong Chen Xin Lu | 2021 | National Science Review2021，8，11： | 3 |
| 9 | Computation of minimum and optimal instreamecological flow for the Yiluohe River 显示文摘 | XIA Ziqiang LI Qiongfan GUO Lidan | 2007 | IAHS Redbook2007，315，： | 1 |
| 10 | 显示文摘 | Li Duxin Guo Ziqiang Lan Weidong | 1998 | Chinese Journal of Applied Chemistry1998，15，： | 1 |
| 11 | A comparison study on the interactions of two oligosaccharides with tobacco cells by time-resolved fluorometric method显示文摘 | Guo Weihua Yin Heng Ye Ziqiang | 2012 | Carbohydrate Polymers2012，90，1： | 1 |
| 12 | Model experimental research on deformation and subsidence characteristics of ground and wall rock due to mining under thick overlying terrane显示文摘 | Weizhong Ren Chengmai Guo Ziqiang Peng Yonggang Wang | 2010 | International Journal of Rock Mechanics and Mining Sciences2010，，4： | 1 |
| 13 | Macular and Retinal Nerve Fiber Layer Thickness Measurements in Normal Eyes With the Stratus OCT, the Cirrus HD-OCT, and the Topcon 3D OCT-1000显示文摘 | Jingjing Huang Xing Liu Ziqiang Wu Xinxing Guo Hongzhi Xu Laurie Dustin Srinivas Sadda | 2011 | Journal of Glaucoma2011，，2： | 1 |
| 14 | Increased expression of S100A6 promotes cell proliferation and migration in human hepatocellular carcinoma显示文摘 | Ziqiang Li Mei Tang Bo Ling Shiying Liu Yu Zheng Chunlai Nie Zhu Yuan Liangxue Zhou Gang Guo Aiping Tong Yuquan Wei | 2014 | Journal of Molecular Medicine2014，，3： | 1 |
| 15 | Rice sl-MH-1 mutant induces cell death and confers blast resistance via the synergistic roles of signaling systems显示文摘Serotonin is ubiquitous across all forms of life and functions in responses to biotic and abiotic stresses.In rice,the conversion of tryptamine to serotonin is catalyzed by Sekiguchi lesion(SL).Previous studies have identified an sl mutation(a null mutation of SL)in several rice varieties and confirmed its increase of resistance and cell death.However,a systematic understanding of the reprogrammed cellular processes causing cell death and resistance is lacking.We performed a multi-omics analysis to clarify the fundamental mechanisms at the protein,gene transcript,and metabolite levels.We found that cell death and Magnaporthe oryzae(M.oryzae)infection of the sl-MH-1 mutant activated plant hormone signal transduction involving salicylic acid(SA),jasmonic acid(JA),and abscisic acid(ABA)in multiple regulatory layers.We characterized the dynamic changes of several key hormone levels during disease progression and under the cell death conditions and showed that SA and JA positively regulated rice cell death and disease resistance.SL-overexpressing lines confirmed that the sl-MH-1 mutant positively regulated rice resistance to M.oryzae.Our studies shed light on cell death and facilitate further mechanistic dissection of programmed cell death in rice. | Dagang Tian Yan Lin Shengping Li Yiyang Cao Gang Li Xinrui Guo Ziqiang Chen Zaijie Chen Feng Wang Zonghua Wang | 2022 | The Crop Journal2022，10，6： | 0 |
| 16 | Advances in the Medicinal Value of Constructed Wetland Plants for Treating Rural Domestic Sewage显示文摘Firstly,the advantages and disadvantages of constructed wetlands for treating rural domestic sewage are introduced.Secondly,the types of constructed wetland plants are introduced.Thirdly,the suitability of using medicinal wetland plants to treat rural domestic sewage is analyzed.Fourthly,the principles of selecting wetland plants with medicinal value are studied.Finally,commonly used constructed wetland plants and their medicinal value are introduced. | Ziqiang AO Jinghua LIANG Meihong BU Yun GUO Mingzhong LONG | 2021 | Meteorological and Environmental Research2021，12，1： | 0 |
| 17 | Polyanionic hydrogel electrolyte enables reversible and durable Zn anode for efficient Zn-based energy storage显示文摘Aqueous Zn-ion energy storage systems,which are expected to be integrated into intelligent electronics as a secure power supply,suffer poor reversibility of Zn anodes,predominantly associated with dendritic growth and side reactions.This study introduces a polyanionic strategy to address these formidable issues by developing a hydrogel electrolyte(PACXHE)with carboxyl groups.Notably,the carboxyl groups within the hydrogel structure establish favorable channels to promote the transport of Zn^(2+)ions.They also expedite the desolvation of hydrated Zn^(2+)ions,leading to enhanced deposition kinetics.Additionally,these functional groups confine interfacial planar diffusion and promote preferential deposition along the(002)plane of Zn,enabling a smooth surface texture of the Zn anode.This multifaceted regulation successfully achieves the suppression of Zn dendrites and side reactions,thereby enhancing the electrochemical reversibility and service life during plating/stripping cycles.Therefore,such an electrolyte demonstrates a high average Coulombic efficiency of 97.7%for 500 cycles in the Zn‖Cu cell and exceptional cyclability with a duration of 480 h at 1 mA cm^(-2)/1 mA h cm^(-2)in the Zn‖Zn cell.Beyond that,the Zn-ion hybrid micro-capacitor employing PACXHE exhibits satisfactory cycling stability,energy density,and practicality for energy storage in flexible,intelligent electronics.The present polyanionic-based hydrogel strategy and the development of PACXHE represent significant advancements in the design of hydrogel electrolytes,paving the way for a more sustainable and efficient future in the energy storage field. | Chunjiang Jin Congcong Yang Hongyu Mi Chenchen Ji Fengjiao Guo Chengzhe Liu Ziqiang Liu Nianjun Yang | 2023 | Journal of Energy Chemistry2023，，11： | 0 |
| 18 | Research on the sampling performance of a new bionic gravity sampler显示文摘Gravity sampling is of vital importance for sampling seabed sediments and understanding submarine sedimentary environments and resources.In this study,a new bionic sampler tube(BST)with non-smooth surface for low-disturbance and rapid sampling is presented.The BST with depressions and swellings on its surface was designed on the model of the non-smooth surface of the dung beetle.Sufficient theoretical calculations,numerical simulations,and experimental tests were carried out to study its sampling performance.The penetration depth,sample length,and frictional drag of the sampler tube were calculated.The finite element model and the coupled Eulerian-Lagrangian(CEL)method were used to analyze and compare its sampling performance.Laboratory and field gravity sampling tests were conducted and the results demonstrated the advantages of the BST in improving sampling performance and in reducing adhesion and drag. | Yongqiang GE Jiamin HE Jin GUO Peihao ZhANG Hao WANG Ziqiang REN Xiaoling LE Ying WANG Yuhong WANG Jiawang CHEN | 2023 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2023，24，8： | 0 |
| 19 | Closely packed Si@C and Sn@C nano-particles anchored by reduced graphene oxide sheet boosting anode performance of lithium ion batteries显示文摘Both silicon and tin are promising anodes for new generation lithium ion batteries due to high lithium storage capacities(theoretically 4200 mA h g^(-1) and 992 mA h g^(-1),respectively).However,their large volumetric expansions(both are above 300%)usually lead to poor cycling stability.In this case,we synthesized closely packed Si@C and Sn@C nano-particles anchored by reduced graphene oxide(denoted as Si@C/Sn@C/rGO)by the way of solution impregnation and subsequent hydrogenation reduction.Sn particles with a diameter of 100 nm are coated by carbon and surrounded by Si@C particles around 40 nm in average diameter through the high-resolution transmission electron microscopy.Expansions of Si and Sn are alleviated by carbon shells,and reduced graphene oxide sheets accommodate their volume changes.The prepared Si@C/Sn@C/rGO electrode delivers an enhanced initial coulombic efficiency(78%),rate capability and greatly improved cycle stability(a high reversible capacity of nearly 1000 mA h g^(-1) is achieved after 300 cycles at a current density of 1000 mA g^(-1)).It can be believed that packing Sn@C nano-particles with Si@C relieves the volume expansion of both and releases the expansion stresses.Sn@C particles enhance anode process kinetics by reducing charge transfer resistance and increasing lithium ion diffusion coefficient.The present work provides a viable strategy for facilely synthesizing silicon-tin-carbon composite anode with long life. | Chaoye Zhu Yao Zhang Ziqiang Wu Zhihong Ma Xinli Guo Fuyi Guo Jiakun Zhang Yushu Li | 2021 | Journal of Materials Science & Technology2021，，28： | 0 |
| 20 | Ethylene Biology Blooms from Fundamenta Research to Postharvest Applications显示文摘 | Ziqiang Zhu Ziqiang Xian Hongwei Guo Zhengguo Li | 2016 | Molecular Plant2016，9，1： | 0 |
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