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46篇 您的检索式:作者名="Guoqing Shen"
    题名 作者 年代 出处 被引量
1Immunomodulatory effects of Caulerpa racemosa var peltata polysaccharide and its selenizing product on T lymphocytes and NK cells in mice显示文摘A polysaccharide, CrvpPS, was isolated from Caulerpa racemosa var peltata. It was reacted with nano-selenium in distilled water containing ascorbic acid (Vit C) to form a stable CrvpPS-nano-Se complex. The immunomodulatory effects of CrvpPS and CrvpPS-nano-Se on T lymphocytes subgroups and NK cells in mice were investigated. After intragastric administration for 10 days separately, both CrvpPS and CrvpPS-nano-Se showed significant stimulatory functions to thymus gland of mice. Moreover, the CrvpPS-nano-Se induced the percentage of CD3+, CD3+CD4+, NK cells and the CD4+/CD8+ value to increase significantly (P<0.05) when analyzed by flow cytometry, which is better than the CrvpPS, sucrose-nano-Se, and even the positive drug levamisole.SHEN WeiZai WANG Hui GUO GuoQing TUO JingJing 2008Science China(Life Sciences)2008,51,9:6
2Cyclospora cayetanensis infections among diarrheal outpatients in Shanghai: a retrospective case study显示文摘Cyclospora cayetanensis 是引起世界范围的地方性、流行的人的腹泻的 foodborne 和水运的病原体。关于 C 的一些流行病学的研究。在中国的 cayetanensis 感染被进行了。在 2013 期间, 291 个凳子标本的一个总数在城市的上海在一所医院与腹泻从病人被收集。C。, cayetanensis 没被传统的显微镜学在任何凳子标本检测五个凳子标本(1.72% , 5/291 ) 由 PCR 是积极的。分子的技术证实的这些积极盒子都在成年的组(吝啬的年龄 27.8 年;2.94% , 5/170 ) 与水的腹泻。显著感染发生在 5 月和 7 月的雨季。顺序和 C 的部分 18S rRNA 基因的种系发生的分析。cayetanensis 孤立这个寄生虫的显示出的 intra 种类差异。第一次,这研究显示出那 C。cayetanensis 是在有在上海的腹泻的门诊病人的病原体,在底层的虽然。然而,在这些病人的这个寄生虫的传播动力学仍然保持不明确。Yanyan Jiang Zhongying Yuan Guoqing Zang Dan Li Ying Wang Yi Zhang Hua Liu Jianping Cao Yujuan Shen 2018Frontiers of Medicine2018,12,1:5
3中国东部沿海杨树人工林养分重吸收和化学计量对氮添加的响应显示文摘叶片养分重吸收对土壤养分的变化很敏感。然而,我们尚不清楚氮沉降如何影响植物大量元素重吸收率。杨树(Populus deltoids)是世界上栽培最广泛的阔叶树种之一。本文研究了在氮添加条件下,杨树重吸收率及其化学计量比的规律和主要驱动因素。通过一个4年的氮添加实验,我们探究中国东部沿海两个林分(8和12年)杨树人工林重吸收率及其化学计量比对氮添加的响应。我们测定了在一系列氮添加浓度水平(0、50、100、150、300 kg N ha^(−1) yr^(−1))下,土壤和叶片(包括绿叶和落叶)中氮、磷、钾、钙、镁的浓度。研究结果表明,除钙元素重吸收率和钙、镁元素重吸收率化学计量比外,氮添加对两个林分大量元素重吸收率及其化学计量比都没有显著影响。氮、磷重吸收率尺度斜率在不同氮添加水平下均小于1,表明氮添加条件下,氮、磷元素重吸收率解耦。养分重吸收率与绿叶中养分含量显著正相关,表明重吸收主要受到绿叶养分调控。我们的研究结果为中国东部沿海地区12年生杨树人工林的生长受氮限制提供了直接证据。Dalong Jiang Qian Li Qinghong Geng Menghua Zhang Chonghua Xu Guoqing Hu Caiqin Shen Honghua Ruan Xia Xu 2021Journal of Plant Ecology2021,14,4:5
4The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus.Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang 2016Science China(Life Sciences)2016,59,9:5
5Study on W-band Sheet Electron Beam Sine Waveguide Traveling-Wave Tube显示文摘XU Xiong WEI Yanyu SHEN Fei GONG Yubin YUE Lingna TANG Tao ZHAO Guoqing WANG Wenxiang 2012Chinese Journal of Electronics2012,21,1:3
6Evaluation of ASTER GDEM in the northeastern margin of Tibetan Plateau in gravity reduction显示文摘In this paper, we first transferred the normal height of ASTER GDEM v2 to GPS ellipsoidal height based on the EGM96, and analyzed the precision of this digital elevation model in the northeastern margin of Tibetan Plateau(NETP) combining with 89 ground GPS measurements. The results demonstrate that the standard deviation of the difference between ASTER GDEM and GPS results is 9.3 m, and the precision of ASTER GDEM in this region is approximately 10 m. We also calculated the free-air gravity anomalies using the relative gravity data and DEM model in NETP. The results show that the gravity anomalies are generally negative with local positive values, ranging from -156 to 43 mGal(10^(-5) m/s^2). At last, we compared the EGM2008 free-air gravity anomalies(FGAs) with the ground gravity measurements, and their spatial patterns are similar. While the point-to-point difference between the modeling and measuring results shows great discrepancy. The free-air gravity anomalies of EGM2008 in this region range from -154 to 96 mGal, and the difference between EGM2008 and the ground measurements ranges from -102 to 50 mGal. The mean difference is -17.34 mGal, and the standard deviation is46.69 mGal, which demonstrates that the EGM2008 has poor precision in the northeastern margin of Tibet Plateau.Guoqing Zhang Wenbin Shen Yiqing Zhu Ying Wang Yawen She 2017Geodesy and Geodynamics2017,8,5:3
7Surface Rainfall and Cloud Budgets Associated with Mei-yu Torrential Rainfall over Eastern China during June 2011显示文摘Surface rainfall and cloud budgets associated with three heavy rainfall events that occurred over eastern China during the mei-yu season in June 2011 were analyzed using 2D cumulus ensemble model simulation data. Model domain mean rainfall showed three peaks in response to three prescribed ascending motion maxima, primarily through the mean moisture convergence during the torrential rainfall period. Prescribed ascending motion throughout the troposphere produced strong convective rainfall during the first(9 June) and third(17–18 June) rainfall events, whereas strong prescribed ascending motion in the mid and upper troposphere and weak subsidence near the surface generated equally important stratiform and convective rainfall during the second rainfall event(14 June). The analysis of surface rainfall budgets reveals that convective rainfall was associated with atmospheric drying during the first event and moisture convergence during the third event. Both stratiform and convective rainfall responded primarily to moisture convergence during the second event. An analysis of grid data shows that the first and third mean rainfall maxima had smaller horizontal scales of the precipitation system than the second.ZHAI Guoqing LI Xiaofan ZHU Peijun SHEN Hangfeng ZHANG Yuanzhi 2014Advances in Atmospheric Sciences2014,31,6:2
8mRNA expression of Rho GTPase-related signaling molecules during rat hippocampal development显示文摘BACKGROUND:Rho GTPase family members have been shown to participate in neurite growth by regulating the neuronal cytoskeleton.However,there are very few reports of developmental roles of signaling molecules related to Rho GTPases. OBJECTIVE:To investigate messenger ribonucleic acid mRNA expression of signaling molecules associated with Rho GTPases,including Rho-A,Rac-1,collapsin response mediator protein 1(CRMP-1),and tubulin(53(Tubβ3) during rat hippocampus development. DESIGN,TIME AND SETTING:A non-randomized,controlled,animal experiment,based on different developmental stages of the rat hippocampus,was performed at the Guangdong Key Laboratory of Tissue Construction and Detection,Institute of Clinical Anatomy,Southern Medical University between December 2005 and July 2007. MATERIALS:Trizol reagent was purchased from Invitrogen,USA.RNA PCR kit(AMV) Ver 3.0 and 150 bp DNA Ladder Marker were purchased from TaKaRa,Japan.Unless otherwise specified,all other reagents were purchased from Sigma-Aldrich,USA. METHODS:Twenty-five Sprague Dawley rats were assigned to five groups(n = 5) according to developmental stages:embryonic(embryonic 15 days),neonatal(postnatal 5 days),juvenile (postnatal 1 month),adult(postnatal 3 months),and senile(postnatal 18 months). MAIN OUTCOME MEASURES:Detection of mRNA expression of Rho-A,Rac-1,CRMP-1,and Tubβ3 during various hippocampal developmental stages by reverse-transcription polymerase chain reaction. RESULTS:Hippocampal mRNA expression of Rho-A,as well as Rac-1,reached peak levels at embryonic,juvenile,and senile stages,and was relatively less during neonatal and adult stages. mRNA expression of Rac-1 was greater than Rho-A during each hippocampal developmental stage. CRMP-1 mRNA expression levels were as follows:embryonic>neonatal>juvenile>adultneonatal>juvenile>adult = senile. CONCLUSION:Rho-A and Rac-1 shared similar expression profiles,which demonstrated similar variations during the entire rat hippocampus developmental process.However,Rac-1 mRNA expression remained greater than Rho-A.Both CRMP-1 and Tubβ3 mRNA expression profiles gradually declined during hippocampal development from embryonic to adult stages.Tubβ3 mRNA expression arrested during the adult stage,and CRMP-1 mRNA expression increased during the senile stage.Guoqing Guo Jifeng Zhang Li Xin Jing Chen Weizai Shen Lin Yuan Shizhen Zhong 2009Neural Regeneration Research2009,4,10:2
9Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results.Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang 2020Science China(Physics,Mechanics & Astronomy)2020,63,4:2
10Biomass-based aligned carbon networks with double-layer construction for tunable electromagnetic shielding with ultra-low reflectivity显示文摘Nowadays,carbon frameworks derived from natural biomaterials have attracted extensive attention for electromagnetic interference(EMI)shielding due to their renewability and affordability.However,it is critical and challenging to achieve effective regulation of shielding effectiveness(SE)as well as weaken the strong EM reflection of highly conductive biomass-based carbon materials.Herein,commercial cotton pads with oriented structure were selected as carbonaceous precursor to fabricate aligned carbon networks by pyrolysis,and the EMI SE of the samples with increased temperature of 800-1000℃ can be accurately controlled in the effective range of~21.7-29.1,~27.7-37.1 and~32.7-43.3 d B with high reflection coefficient of>0.8 by changing the cross-angle between the electric-field direction of incident EM waves and the fiber-orientation direction due to the occurrence of opposite internal electric field.Moreover,the further construction of Salisbury absorber-liked double-layer structure could result in an ultralow reflection coefficient of only~0.06 but enhanced SE variation range up to~38.7-49.3 d B during the adjustment of cross-angle,possibly due to the destructive interference of EM waves in the double-layer carbon networks.This work would provide a simple and effective way for constructing high-performance biomass carbon materials with adjustable EMI shielding and ultra-low reflectivity.Jiali Chen Da Yi Xichen Jia Guoqing Wang Zhouping Sun Lihua Zhang Yinfeng Liu Bin Shen Wenge Zheng 2022Journal of Materials Science & Technology2022,,8:2
11Validation of the simplified criteria for diagnosis of autoimmune hepatitis in Chinese patients显示文摘Dekai Qiu Qixia Wang Hui Wang Qing Xie Guoqing Zang Hong Jiang Chuantao Tu Jinsheng Guo Shuncai Zhang Jianshe Wang Yi Lu Ying Han Lei Shen Xiaoyu Chen Xiqi Hu Xiaojin Wang Chengwei Chen Qingchun Fu Xiong Ma 2010Journal of Hepatology2010,,:2
12Combined effect of heavy metals and polycyclic aromatic hydrocarbons on urease activity in soil显示文摘Shen Guoqing Lu Yitong 2006Ecotoxicology and Environmental Safety2006,63,:1
13Soil quality assessment of Albic soils with different productivities for eastern China显示文摘Zhanjun Liu Wei Zhou Jianbo Shen Shutian Li Ping He Guoqing Liang 2014Soil & Tillage Research2014,,:1
14Status and fuzzy comprehensive assessment of combined heavy metal and organo-chlorine pesticide pollution in the Taihu Lake region of China显示文摘SHEN Guoqing LU Yitong WANG Meinong 2005Journal of Environmental Management2005,76,4:1
15Status and fuzzy comprehensive assessment of combined heavy metal and organo-chlorine pesticide pollution in the Taihu Lake region of China显示文摘Shen Guoqing Lu Yitong Wang Meinong 2005Journal of Environmental Management2005,76,4:1
16Status and Fuzzy Comprehensive Assessment of Combined Heavy Metal and Organo-chlorine Pesticide Pollution in the Taihu Lake Region of China显示文摘Guoqing Shen Yitong Lu Meinong Wang Yongquan Sun 2005Journal of Environmental Management2005,76,4:1
17Imidaclopfid-induced hormesis on the fecundity and juvenile hormone levels of the green peach a- phid Myzus persicae(Sulzer) 显示文摘Yu Yueshu Shen Guoqing Zhu Honglin 2010Pesticide Biochemistry and Physiology2010,,98:1
18Combined effect of heavy metals and polycyclic aromatic hydrocarbons on urease activity in soil 显示文摘SHEN Guoqing LU Yitong HONG Jingbo 2006Ecotoxicology and Environmental Safety2006,63,3:1
19Relationship between Ti/Al ratio and stress-rupture properties in nickel-based superalloy显示文摘Yulai Xu Lei Zhang Jun Li Xueshan Xiao Xiuli Cao Guoqing Jia Zhi Shen 2012Materials Science & Engineering A2012,,:1
20Influence of phenanthrene on cadmium toxicity to soil enzymes and microbial growth显示文摘Guoqing Shen Linkui Cao Yitong Lu 2005Environmental Science and Pollution Research2005,12,5:1
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