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| 1 | Towards 6G wireless communication networks:vision,enabling technologies,and new paradigm shifts显示文摘The fifth generation(5G)wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized,such as mass connectivity,ultra-reliability,and guaranteed low latency.However,5G will not meet all requirements of the future in 2030 and beyond,and sixth generation(6G)wireless communication networks are expected to provide global coverage,enhanced spectral/energy/cost efficiency,better intelligence level and security,etc.To meet these requirements,6G networks will rely on new enabling technologies,i.e.,air interface and transmission technologies and novel network architecture,such as waveform design,multiple access,channel coding schemes,multi-antenna technologies,network slicing,cell-free architecture,and cloud/fog/edge computing.Our vision on 6G is that it will have four new paradigm shifts.First,to satisfy the requirement of global coverage,6G will not be limited to terrestrial communication networks,which will need to be complemented with non-terrestrial networks such as satellite and unmanned aerial vehicle(UAV)communication networks,thus achieving a space-airground-sea integrated communication network.Second,all spectra will be fully explored to further increase data rates and connection density,including the sub-6GHz,millimeter wave(mmWave),terahertz(THz),and optical frequency bands.Third,facing the big datasets generated by the use of extremely heterogeneous networks,diverse communication scenarios,large numbers of antennas,wide bandwidths,and new service requirements,6G networks will enable a new range of smart applications with the aid of artificial intelligence(AI)and big data technologies.Fourth,network security will have to be strengthened when developing 6G networks.This article provides a comprehensive survey of recent advances and future trends in these four aspects.Clearly,6G with additional technical requirements beyond those of 5G will enable faster and further communications to the extent that the boundary between physical and cyber worlds disappears. | Xiaohu YOU Cheng-Xiang WANG Jie HUANG Xiqi GAO Zaichen ZHANG Mao WANG Yongming HUANG Chuan ZHANG Yanxiang JIANG Jiaheng WANG Min ZHU Bin SHENG Dongming WANG Zhiwen PAN Pengcheng ZHU Yang YANG Zening LIU Ping ZHANG Xiaofeng TAO Shaoqian LI Zhi CHEN Xinying MA Chih-Lin I Shuangfeng HAN Ke LI Chengkang PAN Zhimin ZHENG Lajos HANZO Xuemin(Sherman)SHEN Yingjie Jay GUO Zhiguo DING Harald HAAS Wen TONG Peiying ZHU Ganghua YANG Jun WANG Erik GLARSSON Hien Quoc NGO Wei HONG Haiming WANG Debin HOU Jixin CHEN Zhe CHEN Zhangcheng HAO Geoffrey Ye LI Rahim TAFAZOLLI Yue GAO HVincent POOR Gerhard P.FETTWEIS Ying-Chang LIANG | 2021 | Science China(Information Sciences)2021，64，1： | 122 |
| 2 | A 4-bp Insertion at ZmPLA 1 Encoding a Putative Phospholipase A Generates Haploid Induction in Maize显示文摘 | Chenxu Liu Xiang Li Dexuan Meng Yu Zhong Chen Chen Xin Dong Xiaowei Xu Baojian Chen Wei Li Liang Li Xiaolong Tian Haiming Zhao Weibin Song Haishan Luo Qinghua Zhang Jinsheng Lai Weiwei Jin Jianbing Yan Shaojiang Chen | 2017 | Molecular Plant2017，10，3： | 39 |
| 3 | Erucic acid from Isatis indigotica Fort. suppresses influenza A virus replication and inflammation in vitro and in vivo through modulation of NF-kB and p38 MAPK pathway显示文摘Isatis indigotica Fort.(Ban-Lan-Gen)is an herbal medicine prescribed for influenza treatment.However,its active components and mode of action remain mostly unknown.In the present study,erucic acid was isolated from Isatis indigotica Fort.,and subsequently its underlying mechanism against influenza A virus(IAV)infection was investigated in vitro and in vivo.Our results demonstrated that erucic acid exhibited broad-spectrum antiviral activity against IAV resulting from reduction of viral polymerase transcription activity.Erucic acid was found to exert inhibitory effects on IAV or viral(v)RNA-induced pro-inflam-matory mediators as well as interferons(IFNs).The molecular mechanism by which erucic acid with antiviral and anti-inflammatory properties was attributed to inactivation of NF-kB and p38 MAPK signaling.Furthermore,the NF-kB and p38 MAPK inhibitory effect of erucic acid led to diminishing the transcriptional activity of interferon-stimulated gene factor 3(ISGF-3),and thereby reducing IAV-triggered pro-inflammatory response amplification in IFN-β-sensitized cells.Additionally,IAV-or vRNA-triggered apoptosis of alveolar epithelial A549 cells was prevented by erucic acid.In vivo,erucic acid administration consistently displayed decreased lung viral load and viral antigens expression.Meanwhile,erucic acid markedly reduced CD8+cytotoxic T lymphocyte(CTL)recruitment,pro-apoptotic signaling,hyperactivity of multiple signaling pathways,and exacerbated immune inflammation in the lung,which resulted in decreased lung injury and mortality in mice with a mouse-adapted A/FM/1/47-MA(H1N1)strain infection.Our findings provided a mechanistic basis for the action of erucic acid against IAV-mediated inflammation and injury,suggesting that erucic acid may have a therapeutic potential in the treatment of influenza. | Xiaoli Liang Yuan Huang Xiping Pan Yanbing Hao Xiaowei Chen Haiming Jiang Jing Li Beixian Zhou Zifeng Yang | 2020 | Journal of Pharmaceutical Analysis2020，10，2： | 10 |
| 4 | IEEE 802.11aj(45GHz):A New Very High Throughput Millimeter-Wave WLAN System显示文摘This paper presents an overview of a new very high throughput millimeterwave WLAN system operating at 45 GHz band. We begin by reviewing standards process of IEEE 802.11aj(45GHz). Then the frequency spectrum allocation at 45 GHz band is introduced. Next, the channel measurement and mod-eling is given. Specifically, the millimeter-wave MIMO for physical layer enhancement is given in detail. | WANG Haiming HONG Wei CHEN Jixin SUN Bo PENG Xiaoming | 2014 | China Communications2014，11，6： | 10 |
| 5 | Low-dose real-time X-ray imaging with nontoxic double perovskite scintillators显示文摘X-rays are widely used in probing inside information nondestructively,enabling broad applications in the medical radiography and electronic industries.X-ray imaging based on emerging lead halide perovskite scintillators has received extensive attention recently.However,the strong self-absorption,relatively low light yield and lead toxicity of these perovskites restrict their practical applications.Here,we report a series of nontoxic double-perovskite scintillators of Cs_(2)Ag_(0.6)Na_(0.4)In_(1-y)Bi_(y)Cl_(6).By controlling the content of the heavy atom Bi^(3+),the X-ray absorption coefficient,radiative emission efficiency,light yield and light decay were manipulated to maximise the scintillator performance.A light yield of up to 39,000±7000 photons/MeV for Cs_(2)Ag_(0.6)Na_(0.4)In_(0.85)Bi_(0.15)Cl_(6) was obtained,which is much higher than that for the previously reported lead halide perovskite colloidal CsPbBr_(3)(21,000 photons/MeV).The large Stokes shift between the radioluminescence(RL)and absorption spectra benefiting from self-trapped excitons(STEs)led to a negligible selfabsorption effect.Given the high light output and fast light decay of this scintillator,static X-ray imaging was attained under an extremely low dose of ∼1μGy_(air),and dynamic X-ray imaging of finger bending without a ghosting effect was demonstrated under a low-dose rate of 47.2μGy_(air) s^(−1).After thermal treatment at 85℃ for 50 h followed by X-ray irradiation for 50 h in ambient air,the scintillator performance in terms of the RL intensity and X-ray image quality remained almost unchanged.Our results shed light on exploring highly competitive scintillators beyond the scope of lead halide perovskites,not only for avoiding toxicity but also for better performance. | Wenjuan Zhu Wenbo Ma Yirong Su Zeng Chen Xinya Chen Yaoguang Ma Lizhong Bai Wenge Xiao Tianyu Liu Haiming Zhu Xiaofeng Liu Huafeng Liu Xu Liu Yang(Michael)Yang | 2020 | Light(Science & Applications)2020，9，1： | 9 |
| 6 | Piecewise linear mapping algorithm for SAR raw data compression显示文摘When the saturation degree (SD) of space-borne SAR raw data is high, the per-formance of conventional block adaptive quantization (BAQ) deteriorates obviously. In order to overcome the drawback, this paper studies the mapping between the average signal magnitude (ASM) and the standard deviation of the input signal (SDIS) to the A/D from the original reference. Then, it points out the mistake of the mapping and introduces the concept of the standard deviation of the output signal (SDOS) from the A/D. After that, this paper educes the mapping between the ASM and SDOS from the A/D. Monte-Carlo experiment shows that none of the above two mappings is the optimal in the whole set of SD. Thus, this paper proposes the concept of piecewise linear mapping and the searching algorithm in the whole set of SD. According to the linear part, this paper gives the certification and analytical value of k and for nonlinear part, and utilizes the searching algorithm mentioned above to search the corresponding value of k. Experimental results based on simulated data and real data show that the performance of new algorithm is better than conventional BAQ when raw data is in heavy SD. | QI HaiMing YU WeiDong CHEN Xi | 2008 | Science in China(Series F)2008，51，12： | 9 |
| 7 | Assessment of the Ecological Security in the Three Gorges Reservoir Area by Using the Ecological Footprint Method显示文摘The ecological footprint concept and its calculation models are useful for the measurement of the sustainable level of social and economic development.The ecological security situation of the Three Gorges Reservoir Area(TGRA) was evaluated using this concept in this study.The construction of the Three Gorges Reservoir has led to the change in the ecology and immigration status of TGRA.The ecological footprint method is an important means to study the regional ecological security.Our results suggested that,by excluding the areas for biodiversity conservation(12% of the total land),the ecological footprint per capita was 0.57895 ha,which exceeded the ecological carrying capacity in TGRA.The total ecological deficit was found to be 11,522,193.34 ha,accounting for 95.02% of the ecological carrying capacity.These findings suggested that the ecological security of TGRA was not good.In order to compensate for the ecological deficit,it was essential to introduce natural resources from other regions. | WANG Haiming WANG Hai'e SUN Hongyang WANG Xiaolan LIAO Xiaoyong CHEN Zhijian LI Xianwei | 2012 | Journal of Mountain Science2012，9，6： | 9 |
| 8 | Defective Kernel 39 encodes a PPR protein required for seed development in maize显示文摘RNA editing is a posttranscriptional process that is important in mitochondria and plastids of higher plants. All RNA editing-specific trans-factors reported so far belong to PLS-class of pentatricopeptide repeat(PPR)proteins. Here, we report the map-based cloning and molecular characterization of a defective kernel mutant dek39 in maize. Loss of Dek39 function leads to delayed embryogenesis and endosperm development, reduced kernel size, and seedling lethality. Dek39 encodes an E subclass PPR protein that targets to both mitochondria and chloroplasts, and is involved in RNA editing in mitochondrial NADH dehydrogenase3(nad3) at nad3-247 and nad3-275. C-to-U editing of nad3-275 is not conserved and even lost in Arabidopsis, consistent with the idea that no close DEK39 homologs are present in Arabidopsis. However, the amino acids generated by editing nad3-247 and nad3-275 are highly conserved in many other plant species, and the reductions of editing at these two sites decrease the activity of mitochondria NADH dehydrogenase complex I,indicating that the alteration of amino acid sequence is necessary for Nad3 function. Our results indicate that Dek39 encodes an E sub-class PPR protein that is involved in RNA editing of multiple sites and is necessary for seed development of maize. | Xiaojie Li Wei Gu Silong Sun Zongliang Chen Jing Chen Weibin Song Haiming Zhao Jinsheng Lai | 2018 | Journal of Integrative Plant Biology2018，60，1： | 6 |
| 9 | Refined chronology of prehistoric cultures and its implication for re-evaluating human-environment relations in the Hexi Corridor,northwest China显示文摘The reconstruction of high-resolution chronologies for prehistoric cultures is a prerequisite for understanding the history of human evolution and its relationship with environmental change, and is valuable for exploring the trajectory of transcontinental cultural exchanges in prehistoric time. The Hexi Corridor of northwest China was one of the earliest centers for long-distance culture exchange in the prehistoric world. The timing and sequence of cultural changes in this area remains poorly understood resulting from the lack of radiometric age control. This paper presents a refined radiocarbon(14 C) chronology to resolve the timing of human occupation and cultural evolution in the Hexi Corridor. Radiocarbon dating of crop remains, which have an annual life cycle, has the advantage of eliminating problems such as the carbon stored in ‘old wood’. As a result,14C dates from crop remains are used to test the validity of the14C dates derived from charcoal, bone and plant remains. The resultant database of ages is modelled using the Bayesian approach. The updated chronology presented in this paper shows generally good agreement with the original dates used to constrain cultural evolution in the Hexi Corridor. However, the occupation of the corridor by the Shajing and Shanma Late Bronze Age-Early Iron Age cultures appears to have taken place ~300 years later than previously thought. On the basis of comparing this updated chronology of cultural evolution with palaeoclimatic and historical records, it is proposed that the collapse of the Shajing and Shanma cultures occurred as a result of geopolitical impact rather than climate change. | Yishi YANG Shanjia ZHANG Chris OLDKNOW Menghan QIU Tingting CHEN Haiming LI Yifu CUI Lele REN Guoke CHEN Hui WANG Guanghui DONG | 2019 | Science China Earth Sciences2019，62，10： | 5 |
| 10 | Effects of soil nutrients and climate factors on belowground biomass in an alpine meadow in the source region of the Yangtze-Yellow rivers, Tibetan Plateau of China显示文摘Improving our knowledge of the effects of environmental factors(e.g.soil conditions,precipitation and temperature) on belowground biomass in an alpine grassland is essential for understanding the consequences of carbon storage in this biome.The object of this study is to investigate the relative importance of soil nutrients and climate factors on belowground biomass in an alpine meadow in the source region of the Yangtze and Yellow rivers,Tibetan Plateau.Soil organic carbon(SOC),total nitrogen(TN) and total phosphorous(TP) contents and belowground biomass were measured at 22 sampling sites across an alpine meadow on the Tibetan Plateau.We analyzed the data by using the redundancy analysis to determine the main environmental factors affecting the belowground biomass and the contribution of each factor.The results showed that SOC,TN and TP were the main factors that influenced belowground biomass,and the contribution of SOC,TN and TP on biomass was in the range of 47.87%–72.06% at soil depths of 0–30 cm.Moreover,the combined contribution of annual mean temperature(AMT) and mean annual precipitation(MAP) on belowground biomass ranged from 0.92% to 4.10%.A potential mechanism for the differences in belowground biomass was caused by the variations in soil nitrogen and phosphorous,which were coupled with SOC.A significant correlation was observed between MAP and soil nutrients(SOC,TN and TP) at the soil depth of 0–10 cm(P<0.05).We concluded that precipitation is an important driving force in regulating ecosystem functioning as reflected in variations of soil nutrients(SOC,TN and TP) and dynamics of belowground biomass in alpine grassland ecosystems. | WANG Haiming SUN Jian LI Weipeng WU Jianbo CHEN Youjun LIU Wenhui | 2016 | Journal of Arid Land2016，8，6： | 5 |
| 11 | Opinion dynamics in finance and business: a literature review and research opportunities显示文摘Opinion dynamics is an opinion evolution process of a group of agents,where the final opinion distribution tends to three stable states:consensus,polarization,and fragmentation.At present,the opinion dynamics models have been extensively studied in differrent fields.This paper provides a review of opinion dynamics in finance and business,such as,finance,marketing,e-commerce,politics,and group decision making.Furthermore,identified research challenges have been proposed to promote the future research of this topic. | Quanbo Zha Gang Kou Hengjie Zhang Haiming Liang Xia Chen Cong‑Cong Li Yucheng Dong | 2020 | Financial Innovation2020，6，1： | 5 |
| 12 | Clinical value of Tongguanteng(Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy in the treatment of advanced non-small cell lung cancer: a Meta-analysis显示文摘OBJECTIVE: To investigate the clinical efficacy and safety of Tongguanteng(Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy in the treatment of advanced non-small celllung cancer(NCSLC) compared with chemotherapy alone.METHODS: Databases including Chinese National Knowledge Infrastructure, China Biology Medicine Disc, Wanfang, and MEDLINE were searched until April 1, 2014. Two assessors independently reviewed each trial. The primary outcome was the effective rate(ER) of Tongguanteng(Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy. The secondary outcomes included quality of life improvement rate(QOLIR) and adverse reactions. Statistical calculations were performed by using Cochrane Collaboration Review Manager 5.2.RESULTS: A total of 888 patients from 15 studies,13 randomized controlled trials(RCT) and two controlled clinical trials, were included. Compared with chemotherapy alone, Tongguanteng(Radix seu Herba Marsdeniae Tenacissimae) extract plus chemotherapy significantly improved ER [Risk ratio(RR) =1.32, 95% CI,(1.14, 1.54)](based on 15 studies) and QOLIR [RR = 2.04, 95% CI,(1.69, 2.47)](based on 13studies). Compared with chemotherapy alone,Tongguanteng(Radix seu Herba Marsdeniae Tenacissimae) extract plus chemotherapy significantly inhibited chemotherapy-induced white blood cell decline [RR = 0.79, 95% CI,(0.70, 0.90)(based on 10 studies), chemotherapy-induced platelet decline[RR = 0.77, 95% CI,(0.60, 0.98)](based on 8 studies),and significantly alleviated nausea and vomiting(NV) [RR = 0.83, 95% CI,(0.71, 0.97)](based on 7studies). There was no significant difference in hemoglobin decline between the two therapies [RR =0.88, 95% CI,(0.70, 1.09)](based on 6 studies).CONCLUSION: This Meta-analysis suggests that Tongguanteng(Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy may be more efficacious in the treatment of advanced NSCLC than chemotherapy alone. This effect includes enhancing ER and QOLIR, and weakening chemotherapy toxicity. However, large-scale RCTs are required to further investigate the short- and long-term effects of Tongguanteng(Radix seu Herba Marsdeniae Tenacissimae) extract. | Zhang Haiming Zhang Junli Ding Hao Chen Rui Liang Fengxia | 2016 | Journal of Traditional Chinese Medicine2016，36，3： | 4 |
| 13 | Application of Optical Tweezers in the Research of Molecular Interaction between Lymphocyte Function Associated Antigen-1 and Its Monoclonal Antibody显示文摘Lymphocyte function associated antigen-1 (CD11a/CD18, LFA-1) plays an important role in the structure of the immunological synapse and is required for efficient lysis of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. To study the activation mode of LFA-1 on the NK cell surface, optical tweezers were used in the work. As an emerging technology, optical tweezers are widely used to manipulate microscopic objects and measure the forces of molecular interactions in the field of biological research. In our study, a new platform was constructed to study the single molecular behavior of receptor on cell surface using optical tweezers. Based on the platform, the interaction between an NK cell and a polystyrene microsphere coated with anti-LFA-1 antibody was observed. The result confirmed that the adhesion forces between an NK cell and a polystyrene bead were time-dependent. According to our findings, we propose that anti-LFA-1 antibody may cause the clustering of LFA-1 on NK cell surface. | Haodong Chen Kuikui Ge Yinmei Li Jianguang Wu Yongqiang Gu Haiming Wei Zhigang Tian | 2007 | Cellular & Molecular Immunology2007，4，3： | 3 |
| 14 | Review on modeling and simulation of microstructure evolution during dynamic recrystallization using cellular automaton method显示文摘The macro-mechanical properties of metal and alloy are largely depended on their chemical composition and microstructures resulting from the complicated processing and heat treatment history in industrial production. During these thermoplastic processes, dynamic recovery, dynamic recrystallization, static recovery and static recrystallization are the key microstructural evolution mechanisms. Accurate prediction and precise control of the microstructural evolution are of great importance for designers to achieve excellent mechanical properties for metals and alloys through hot working. Up to date, dynamic recrystallization has been recognized as a powerful mechanism for grain refinement. In-depth understanding of the microstructural evolution of dynamic recrystallization and furthermore to accurately predict and control the microstructure evolution during dynamic recrystallization process has become a research focus in the field of plastic processing. Cellular automaton(CA) method has been commonly employed to simulate the microstructure evolution of dynamic recrystallization due to its unique advantages,for example, it is easier to represent topological features and more realistically reflect the grain boundary migration process. In this paper, the basic ideas and characteristics of the CA method are briefly introduced. The physical mechanisms of dynamic recrystallization are summarized. Meanwhile, the state-of-the-art overview of the CA method of simulating the DRX process is introduced. Furthermore, this paper points out several problems that need to be solved urgently and prospects the development trend of the CA method for simulating the microstructure evolution in dynamic recrystallization. | ZHU HuaJia CHEN Fei ZHANG HaiMing CUI ZhenShan | 2020 | Science China(Technological Sciences)2020，63，3： | 3 |
| 15 | Magnetoresponsive nanozyme:magnetic stimulation on the nanozyme activity of iron oxide nanoparticles显示文摘The iron oxide nanoparticles(IONPs)that combine the nanozyme activity and magnetothermal properties have attracted significant interest for various biomedical applications.However,the effect of magnetic stimulation in fine-tuning the nanozyme activities remains unclear.Here,we have constructed a series of IONPs with different magneto-thermal conversion abilities,and systematically study the effect of magnetic field stimulation on the peroxidase(POD)activity of IONPs.The results show that POD activity is effectively amplified via an in situ alternating magnetic field(AMF)stimulation with no solution temperature rise,and the degree of activity enhancement is closely related to the magnetic heating ability of the IONPs,confirming the origin of activity enhancement arises from the local magnetothermal effect.As the first report to prove magnetothermal regulation on nanozyme activity and to shed lights on the underlying correlation between activity enhancement and the intrinsic specific absorption rate(SAR),this work is expected to provide important support for future design of new magnetoresponsive nanozymes in various practical applications. | Yuan He Xiaoyong Chen Ye Zhang Yanyun Wang Mengyao Cui Galong Li Xiaoli Liu Haiming Fan | 2022 | Science China(Life Sciences)2022，65，1： | 3 |
| 16 | MDM2 SNP309 contributes to tumor susceptibility:A meta-analysis显示文摘潜在地功能的多型性, SNP309,在 MDM2 的倡导者区域,基因在出版研究看了不确定的结果的癌症风险,而是个人被含有。获得在 MDM2 SNP309 和癌症的风险之间的协会的更精确的估计,我们在与肿瘤和 33,046 控制的不同类型包括了 26,160 个盒子的 59 份出版物执行了 70 单个研究的元分析。概括机会比率(或) 并且相应当适当时, 95% 信心间隔(CI ) 用改正效果和随机效果的模型被估计。总的来说,变体遗传型在不同基因模型为所有癌症类型与显著地增加的癌症风险被联系(GG 对 TT:或, 1.123;95% CI, 1.0561.193;GG/GT 对 TT:或, 1.028;95% CI, 1.0061.050 ) 。在成层的分析,为大多数的研究仍然是的增加的风险癌症,亚洲人口,和医院打字 -- 在不同基因模型的 /population-based 研究,而显著地减少了,风险在前列腺癌症被发现(GG 对 TT:或, 0.606;95% CI, 0.4070.903;GG/GT 对 TT:或, 0.748;95% CI, 0.5790.968 ) 。在结论,元分析的数据建议 MDM2 SNP309 是为癌症风险的潜在的 biomarker。 | Xiaoman Wo Dong Han Haiming Sun Yang Liu Xiangning Meng Jing Bai Feng Chen Yang Yu Yan Jin Songbin Fu | 2011 | Journal of Genetics and Genomics2011，38，8： | 3 |
| 17 | Direct load control by distributed imperialist competitive algorithm显示文摘Demand side management techniques have drawn significant attentions along with the development of smart grid.This paper proposes a new direct load control(DLC)model for scheduling interruptible air conditioner loads.The model is coordinated with the unit commitment and economic dispatch to minimize the total operation cost over the whole dispatch horizon.The network constraints are also considered in the model.To ensure the thermal comfort of the occupants,we are among the first to incorporate the advanced two-parameter thermal inertia dynamical model of customer houses into the DLC model to calculate the indoor temperature variation.This paper also proposes a distributed imperialist competitive algorithm to effectively solve the model.The simulation studies prove the efficiency of the proposed methodology. | Fengji LUO Junhua ZHAO Haiming WANG Xiaojiao TONG Yingying CHEN Zhao Yang DONG | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，4： | 3 |
| 18 | Tocilizumab in patients with moderate or severe COVID-19: a randomized, controlled, open-label, multicenter trial显示文摘Tocilizumab has been reported to attenuate the“cytokine storm”in COVID-19 patients.We attempted to verify the effectiveness and safety of tocilizumab therapy in COVID-19 and identify patients most likely to benefit from this treatment.We conducted a randomized,controlled,open-label multicenter trial among COVID-19 patients.The patients were randomly assigned in a 1:1 ratio to receive either tocilizumab in addition to standard care or standard care alone.The cure rate,changes of oxygen saturation and interference,and inflammation biomarkers were observed.Thirty-three patients were randomized to the tocilizumab group,and 32 patients to the control group.The cure rate in the tocilizumab group was higher than that in the control group,but the difference was not statistically significant(94.12%vs.87.10%,rate difference 95%CI−7.19%–21.23%,P=0.4133).The improvement in hypoxia for the tocilizumab group was higher from day 4 onward and statistically significant from day 12(P=0.0359).In moderate disease patients with bilateral pulmonary lesions,the hypoxia ameliorated earlier after tocilizumab treatment,and less patients(1/12,8.33%)needed an increase of inhaled oxygen concentration compared with the controls(4/6,66.67%;rate difference 95%CI−99.17%to−17.50%,P=0.0217).No severe adverse events occurred.More mild temporary adverse events were recorded in tocilizumab recipients(20/34,58.82%)than the controls(4/31,12.90%).Tocilizumab can improve hypoxia without unacceptable side effect profile and significant influences on the time virus load becomes negative.For patients with bilateral pulmonary lesions and elevated IL-6 levels,tocilizumab could be recommended to improve outcome. | Dongsheng Wang Binqing Fu Zhen Peng Dongliang Yang Mingfeng Han Min Li Yun Yang Tianjun Yang Liangye Sun Wei Li Wei Shi Xin Yao Yan Ma Fei Xu Xiaojing Wang Jun Chen Daqing Xia Yubei Sun Lin Dong Jumei Wang Xiaoyu Zhu Min Zhang Yonggang Zhou Aijun Pan Xiaowen Hu Xiaodong Mei Haiming Wei Xiaoling Xu | 2021 | Frontiers of Medicine2021，15，3： | 2 |
| 19 | Dynamic rupture process of the 1999 Chi-Chi,Taiwan,earthquake显示文摘In this study, we preliminarily investigated the dynamic rupture process of the 1999 Chi-Chi, Taiwan, earthquake by using an extended boundary integral equation method, in which the effect of ground surface can be exactly included. Parameters for numerical modeling were carefully assigned based on previous studies. Numerical results indicated that, although many simplifications are assumed, such as the fault plane is planar and all heterogeneities are neglected, distribution of slip is still consistent roughly with the results of kinematic inversion, implying that for earthquakes in which ruptures run up directly to the ground surface, the dynamic processes are controlled by geometry of the fault to a great extent. By taking the common feature inferred by various kinematic inversion studies as a restriction, we found that the critical slip-weakening distance Dc should locate in a narrow region [60 cm, 70 cm], and supershear rupture might occur during this earthquake, if the initial shear stress before the mainshock is close to the local shear strength. | Haiming Zhang Xiaofei Chen | 2009 | Earthquake Science2009，22，1： | 2 |
| 20 | 19.34 cm2 large-area quaternary organic photovoltaic module with 12.36% certified efficiency显示文摘In this study, a quaternary blending strategy was applied in the fabrication of organic photovoltaic devices and large-area modules. As a result, the ultimate quaternary organic solar cells(OSCs) deliver 16.71% efficiency for small-area devices and 13.25% for large-area(19.34 cm2) modules(certified as 12.36%), which is one of the highest efficiencies for organic solar modules to date. Our results have proved the synergistic effects of multiple components in OSCs, providing an effective strategy for achieving high-performance organic photovoltaic devices and modules. | Ziyan Jia Zeng Chen Xu Chen Jizhong Yao Buyi Yan Rui Sheng Haiming Zhu Yang(Michael)Yang | 2021 | Photonics Research2021，9，3： | 2 |
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