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| 1 | Characteristics of dissolved organic matter(DOM) in leachate with different landfill ages显示文摘学习的主要目的是调查溶解有机物(DOM ) 的特征在沥滤通过化学、分光镜、元素的分析与不同垃圾堆年龄吃了。胡敏酸(哈) , fulvic (FA ) ,并且吸水(HyI ) 部分被与阳离子交换尸方法相结合的 XAD-8 树脂孤立并且净化。荧光刺激排放矩阵光谱学(EEM ) 的分析结果表明荧光山峰是为年轻垃圾堆的像蛋白质的荧光沥滤当为中等、旧的垃圾堆的荧光山峰沥滤时,吃了吃分别地是象腐殖一样和象 fulvic 一样荧光。元素的分析证明那碳,氢,和氮内容与垃圾堆年龄减少了,当氧内容增加了时。而且,在这些孤立的部分的氮内容列在后面:哈 >
HyI >
FA。元素的分析,英尺红外,和荧光 EEM 的结果也证实脂肪族的功能的组的芳香的碳和部分更充满沥滤与增加垃圾堆年龄吃了样品。 | HUO Shouliang XI Beidou YU Haichan HE Liansheng FAN Shilei LIU Hongliang | 2008 | Journal of Environmental Sciences2008，20，4： | 52 |
| 2 | Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis显示文摘Complement is known to play a role in alcoholic fatty liver disease (AFLD), but the underlying mechanisms are poorly understood, thereby constraining the development of a rational approach for therapeutic intervention in the complement system. C3 deficiency has been shown to impart protective effects against ethanol-induced hepatic steatosis and inflammation. Here we demonstrate a protection effect in wild-type mice by treatment with CR2-Crry, a specific inhibitor of C3 activation. The expression of glycine transfer (t) RNA-derived fragments (Gly-tRFs) is upregulated in ethanol-fed mice and inhibition of Gly-tRFs in vivo decreases chronic ethanol feeding-induced hepatosteatosis without affecting inflammation. The expression of Gly-tRF was downregulated in C3-deficient or CR2-Crry-treated mice, but not in C5-deficient mice;Gly-tRF expression was restored by the C3 activation products C3a or Asp (C3a-des-Arg) via the regulation of CYP2E1. Transcriptome profiling of hepatic tissues showed that Gly-tRF inhibitors upregulate the expression of sirtuin1 (Sirt1) and subsequently affect downstream lipogenesis and β-oxidation pathways. Mechanistically, Gly-tRF interacts with AGO3 to downregulate Sirt1 expression via sequence complementarity in the 3′ UTR. Notably, the expression levels of C3d, CYP2E1 and Gly-tRF are upregulated, whereas Sirt1 is decreased in AFLD patients compared to healthy controls. Collectively, our findings suggest that C3 activation products contribute to hepatosteatosis by regulating the expression of Gly-tRF. Complement inhibition at the C3 activation step and treatment with Gly-tRF inhibitors may be potential and precise therapeutic approaches for AFLD. | Fudi Zhong Zhigao Hu Keqing Jiang Biao Lei Zhan Wu Guandou Yuan Hongliang Luo Chunqiang Dong Bo Tang Chaowen Zheng Shuai Yang Yonglian Zeng Zhenya Guo Shuiping Yu Huizhao Su Guo Zhang Xiaoqiang Qiu Stephen Tomlinson Songqing He | 2019 | Cell Research2019，29，7： | 14 |
| 3 | Serum IgA,IgM,and IgG responses in COVID-19显示文摘Currently,detecting SARS-CoV-2 RNAs is a standard approach for COVID-19 diagnosis.However,there is an urgent need for reliable and rapid serological diagnostic methods to screen SARS-CoV-2-infected people including those who do not have overt symptoms.Most emerging studies described serological tests based on detection of SARS-CoV-2-specific IgM and IgG.1–4 Although detection of SARS-CoV-2-specific IgA in serum has been reported in few papers,5,6 analyses of IgA levels in a larger number of COVID-19 patients are still lacking. | Huan Ma Weihong Zeng Hongliang He Dan Zhao Dehua Jiang Peigen Zhou Linzhao Cheng Yajuan Li Xiaoling Ma Tengchuan Jin | 2020 | Cellular & Molecular Immunology2020，17，7： | 12 |
| 4 | Zeolitic Imidazolate Framework 8-Derived Au@ZnO for Efficient and Robust Photocatalytic Degradation of Tetracycline显示文摘Summary of main observation and conclusion Tetracycline (TC) and other antibiotics accumulated in groundwater and soil pollute ecological environment and threaten human health. Gold nan oparticles doped on photocatalysts are able to enhance the photodegradation efficiency during removing these antibiotics, but preparation of Au nanoparticles of well-dispersion on photocatalysts remains challenging. In this work, zeolite imidazolate (ZIF-8) was employed as the precursor to prepare Au@ZnO photocatalyst via impregnation and in-situ reduction method to efficiently degrade the tetracycline in the aqueous solution. Au nanoparticles are of 10 nm in size and uniformly dispersed on the surfaces of ZnO microstructures. The as-prepared Au@ZnO is able to remove 85.5% of TC of 0.010 mg/mL within 2h, presenting higher photocatalytic activity than pure ZnO catalyst. Most importantly, the catalyst shows its superior stability after five cycles without structure and activity changing. The mechanism of the photocatalytic degradation was discussed in detail. | Bijun Gao Jin Zhou Hongliang Wang Guping Zhang Jinghui He Qingfeng Xu Najun Li Dongyun Chen Hua Li Jianmei Lu | 2019 | Chinese Journal of Chemistry2019，37，2： | 6 |
| 5 | Colorectal cancer burden,trends and risk factors in China:A review and comparison with the United States显示文摘Objective:China and the United States(the U.S.)have the heaviest colorectal cancer(CRC)burden with considerable variations in temporal trends.This study aims to analyze the temporal patterns of CRC burden and its risk factors in China and the U.S.across the past three decades.Methods:Data were extracted from the Global Burden of Disease(GBD)Study in 2019,including cases,deaths,disability-adjusted life-years(DALYs),age-standardized rate(ASR),and summary exposure value(SEV)of CRC in China and the U.S.between 1990 and 2019.Annual average percentage changes(AAPCs)of CRC burden were calculated using the Joinpoint regression model.The mortality in CRC attributable to potential risk factors was characterized by countries,gender,and age groups.Results:In 2019,there were 607,900 and 227,241 CRC cases,and 261,777 and 84,026 CRC deaths in China and the U.S.,respectively.The age-standardized incidence rate(ASIR)was 30.55 per 100,000 in China and 41.86 per100,000 in the U.S.,and the age-standardized mortality rate(ASMR)was 13.86 per 100,000 in China and 14.77 per100,000 in the U.S.CRC incidence,mortality,and DALY rate in the U.S.showed downward trends in the past three decades(AAPC=-0.47,-1.06,and-0.88,respectively),while upward trends were observed in China(AAPC=3.11,1.05,and 0.91,respectively).Among the cause of CRC,the leading risk factor contributing to CRC death was low milk in China and smoking in the U.S.,respectively.Conclusions:From 1990 to 2019,the burden of CRC in China increased dramatically,particularly for males and middle-aged and elderly people.The management of the major risk factors associated with the high burden of CRC should be enhanced. | Qianru Li Hongliang Wu Maomao Cao He Li Siyi He Fan Yang Xinxin Yan Shaoli Zhang Yi Teng Changfa Xia Ji Peng Wanqing Chen | 2022 | Chinese Journal of Cancer Research2022，34，5： | 6 |
| 6 | Magnetic performance and corrosion resistance of electroless plating CoWP film显示文摘The CoWP film with good magnetic performance and corrosion resistance was electrolessly plated from alkaline solution. The technical parameters of the electroless plating system were optimized. When the pH value of electroless plating solution was 11.0 and the reducing agent (NaH2PO2) content was 0.4 mol L 1, the target chemical reactions proceeded in the electroless plating solution smoothly with negligible interference and side effects. CoWP film prepared under optimal deposition condition contained more hexagonal close-packed (hcp) cobalt (ε-Co) of [110] and crystallographic orientation of Co [002]. VSM analysis reveals that the saturation magnetization of the CoWP film is 100~220 Am2 kg 1 and coercivity is (2.87~4.38)×104 A·cm 1. The corrosion behavior of CoWP film in 3.5% NaCl aqueous solution was studied by electrochemical experiments. The results prove that the corrosion resistance of the CoWP film deposited under the optimal depo-sition condition exhibites relatively lower corrosion current of (3.054~3.162)×10 6 A·cm 2. The surface morphology analysis indicates that the film is smooth and composed of regular-shaped crystallites. | Jiang, Li Pan, Shanshan Lu, Jianbiao Ke, Xin He, Wenhao Yu, Yundan Wei, Guoying Ge, Hongliang | 2012 | Rare Metals2012，31，3： | 6 |
| 7 | Activin A prevents neuron-like PC12 cell apoptosis after oxygen-glucose deprivation显示文摘In this study, PC12 cells were induced to differentiate into neuron-like cells using nerve growth facto and were subjected to oxygen-glucose deprivation. Cells were treated with 0, 10, 20, 30, 50, 100 ng/mL exogenous Activin A. The 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl tetrazolium bromide assay and Hoechst 33324 staining showed that the survival percentage of PC12 cells significantly decreased and the rate of apoptosis significantly increased after oxygen-glucose deprivation. Exogenous Activin A significantly increased the survival percentage of PC12 cells in a dose-dependent manner. Reverse transcription-PCR results revealed a significant increase in Activin receptor IIA, Smad3 and Smad4 mRNA levels, which are key sites in the Activin A/Smads signaling pathway, in neuron-like cells subjected to oxygen-glucose deprivation, while mRNA expression of the apoptosis-regulation gene caspase-3 decreased. Our experimental findings indicate that exogenous Activin A plays an anti-apoptotic role and protects neurons by means of activating the Activin A/Smads signaling pathway. | Guihua Xu Jinting He Hongliang Guo Chunli Mei Jiaoqi Wang Zhongshu Li Han Chen Jing Mang Hong Yang Zhongxin Xu | 2013 | Neural Regeneration Research2013，8，11： | 5 |
| 8 | Circular cladding waveguides in Pr:YAG fabricated by femtosecond laser inscription:Raman,luminescence properties and guiding performance显示文摘We report on the fabrication of circular cladding waveguides with cross-section diameters of 60−120μm in Pr:YAG crystal by applying femtosecond laser inscription.The fabricated waveguides present 2D guidance on the cross-section and fairly low propagation losses.Multiple high-order guiding modes are observed in waveguides with different diameters.Corresponding simulation results reveal the origin of a specific kind of guiding modes.Confocal micro-Raman(μ-Raman)experiments demonstrate the modification effects in femtosecond laser affected areas and ascertain the refractive index induced guiding mechanism.In addition,luminescence emission properties of Pr3+ions at waveguide volume are well preserved during the femtosecond laser inscription process,which may result in a potential high-power visible waveguide laser. | Quanxin Yang Hongliang Liu Shan He Qingyu Tian Bin Xu Pengfei Wu | 2021 | Opto-Electronic Advances2021，4，2： | 4 |
| 9 | Determination of abscisic acid based on the fluorescent quenching of quantum dots显示文摘The quenching mechanism of the fluorescence of quantum dots by abscisic acid has been systematically investigated.The quenching constant KSV = 5.1 × 1011 / M was obtained under the optimized condition.On the basis of that,a very sensitive method for the determination of abscisic acid has been developed.The linear equation was F0/F = 0.9309 + 0.5072 C(pmol/L) and its linear range was 0.2-3.0 pmol/L with a correlation coefficient of 0.9939.The limit of detection was 0.09 pmol/L. | ZHANG Lei,GUAN HongLiang & HE ZhiKe Key Laboratory of Analytical Chemistry for Biology and Medicine,Ministry of Education College of Chemistry and Molecular Sciences,Wuhan University,Wuhan 430072,China | 2010 | Science China Chemistry2010，53，1： | 4 |
| 10 | A super pan-genomic landscape of rice显示文摘Pan-genomes from large natural populations can capture genetic diversity and reveal genomic complexity.Using de novo longread assembly,we generated a graph-based super pan-genome of rice consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.Our pan-genome reveals extensive structural variations(SVs)and gene presence/absence variations.Additionally,our pan-genome enables the accurate identification of nucleotide-binding leucine-rich repeat genes and characterization of their inter-and intraspecific diversity.Moreover,we uncovered grain weight-associated SVs which specify traits by affecting the expression of their nearby genes.We characterized genetic variants associated with submergence tolerance,seed shattering and plant architecture and found independent selection for a common set of genes that drove adaptation and domestication in Asian and African rice.This super pan-genome facilitates pinpointing of lineage-specific haplotypes for trait-associated genes and provides insights into the evolutionary events that have shaped the genomic architecture of various rice species. | Lianguang Shang Xiaoxia Li Huiying He Qiaoling Yuan Yanni Song Zhaoran Wei Hai Lin Min Hu Fengli Zhao Chao Zhang Yuhua Li Hongsheng Gao Tianyi Wang Xiangpei Liu Hong Zhang Ya Zhang Shuaimin Cao Xiaoman Yu Bintao Zhang Yong Zhang Yiqing Tan Mao Qin Cheng Ai Yingxue Yang Bin Zhang Zhiqiang Hu Hongru Wang Yang Lv Yuexing Wang Jie Ma Quan Wang Hongwei Lu Zhe Wu Shanlin Liu Zongyi Sun Hongliang Zhang Longbiao Guo Zichao Li Yongfeng Zhou Jiayang Li Zuofeng Zhu Guosheng Xiong Jue Ruan Qian Qian | 2022 | Cell Research2022，32，10： | 3 |
| 11 | Sunway supercomputer architecture towards exascale computing:analysis and practice显示文摘In recent years,the improvements of system performance and energy efficiency for supercomputers have faced increasing challenges,which create more intensive demands on the architecture design for realizing exascale computing.This paper first analyzes the main requirements of exascale computing on the aspects of the parallel computing application and supercomputing center operation.Afterwards,a mapping scheme of'demands-challenges-architecture'is proposed.Then,the major challenges of exascale supercomputer,such as scalability,power consumption,data movement,programming and availability,are thoroughly analyzed,and the corresponding appropriate solutions are proposed.Moreover,this paper proposes the Sunway computer architecture towards exascale computing in which the many-core processor,network chipset and software system are all domestically-designed.The technology roadmap of Sunway supercomputer will hold the comprehensive design methods for the architecture,including the processor,interconnect network,assembly structure,power supply,cooling system,system software,parallel algorithm and application support,promising great advances for exascale supercomputing. | Jiangang GAO Fang ZHENG Fengbin QI Yajun DING Hongliang LI Hongsheng LU Wangquan HE Hongmei WEI Lifeng JIN Xin LIU Daoyong GONG Fei WANG Yan ZHENG Honghui SUN Zhou ZHOU Yong LIU Hongtao YOU | 2021 | Science China(Information Sciences)2021，64，4： | 3 |
| 12 | Li-ion battery material under high pressure:amorphization and enhanced conductivity of Li_4Ti_5O_(12)显示文摘Lithium titanium oxide(Li_4Ti_5O_(12),LTO),a‘zero-strain’anode material for lithium-ion batteries,exhibits excellent cycling performance.However,its poor conductivity highly limits its applications.Here,the structural stability and conductivity of LTO were studied using in situ high-pressure measurements and first-principles calculations.LTO underwent a pressure-induced amorphization(PIA)at 26.9 GPa.The impedance spectroscopy revealed that the conductivity of LTO improved significantly after amorphization and that the conductivity of decompressed amorphous LTO increased by an order of magnitude compared with its starting phase.Furthermore,our calculations demonstrated that the different compressibility of the Li O_6 and Ti O_6 octahedra in the structure was crucial for the PIA.The amorphous phase promotes Li^+ diffusion and enhances its ionic conductivity by providing defects for ion migration.Our results not only provide an insight into the pressure depended structural properties of a spinel-like material,but also facilitate exploration of the interplay between PIA and conductivity. | Yanwei Huang Yu He Howard Sheng Xia Lu Haini Dong Sudeshna Samanta Hongliang Dong Xifeng Li Duck Young Kim Ho-kwang Mao Yuzi Liu Heping Li Hong Li Lin Wang | 2019 | National Science Review2019，6，2： | 2 |
| 13 | Core antigen tests for hepatitis C virus: a meta-analysis显示文摘 | Shuijun Gu Jun Liu Huijun Zhang Baoluo Gu Hanjiang Lai Hongliang Zhou Chaoqi He Yingying Chen | 2012 | Molecular Biology Reports2012，，8： | 2 |
| 14 | Engineering HOF‑Based Mixed‑Matrix Membranes for Efficient CO_(2) Separation显示文摘Hydrogen-bonded organic frameworks(HOFs)have emerged as a new class of crystalline porous materials,and their application in membrane technology needs to be explored.Herein,for the first time,we demonstrated the utilization of HOF-based mixed-matrix membrane for CO_(2) separation.HOF-21,a unique metallo-hydrogen-bonded organic framework material,was designed and processed into nanofillers via amine modulator,uniformly dispersing with Pebax polymer.Featured with the mix-bonded framework,HOF-21 possessed moderate pore size of 0.35 nm and displayed excellent stability under humid feed gas.The chemical functions of multiple binding sites and continuous hydrogen-bonded network jointly facilitated the mass transport of CO_(2).The resulting HOF-21 mixed-matrix membrane exhibited a permeability above 750 Barrer,a selectivity of~40 for CO_(2)/CH_(4) and~60 for CO_(2)/N_(2),surpassing the 2008 Robeson upper bound.This work enlarges the family of mixed-matrix membranes and lays the foundation for HOF membrane development. | Yuhan Wang Yanxiong Ren Yu Cao Xu Liang Guangwei He Hanze Ma Hongliang Dong Xiao Fang Fusheng Pan Zhongyi Jiang | 2023 | Nano-Micro Letters2023，15，4： | 2 |
| 15 | Differentiation of Induced Pluripotent Stem Cells into Male Germ Cells In Vitro through Embryoid Body Formation and Retinoic Acid or Testosterone Induction显示文摘 | Peng Li Hongliang Hu Shi Yang Ruhui Tian Zhenzhen Zhang Wei Zhang Meng Ma Yong Zhu Xizhi Guo Yiran Huang Zuping He Zheng Li Xuan Jin | 2012 | BioMed Research International2012，，： | 2 |
| 16 | A model to determine the lake nutrient standards for drinking water sources in Yunnan-Guizhou Plateau Ecoregion, China显示文摘Lake eutrophication (LE) has become an increasingly severe environmental problem recently. However, there has been no nutrient standard established for LE control in many developing countries such as China. This study proposes a structural equation model to assist in the establishment of a lake nutrient standard for drinking water sources in Yunnan-Guizhou Plateau Ecoregion (Yungui Ecoregion), China. The modeling results indicate that the most predictive indicator for designated use-attainment is total phosphorus (TP) (total effect =-0.43), and chlorophyll a (Chl-a) is recommended as the second important indicator (total effect =-0.41). The model is further used for estimating the probability of use-attainment associated with lake water as a drinking water source and various levels of candidate criteria (based on the reference conditions and the current environmental quality standards for surface water). It is found that these candidate criteria cannot satisfy the designated 100% use-attainment. To achieve the short-term target (85% attainment of the designated use), TP and Chl-a values ought to be less than 0.02 mg/L and 1.4 μg/L, respectively. When used as a long-term target (90% or greater attainment of the designated use), the TP and Chl-a values are suggested to be less than 0.018 mg/L and 1 μg/L, respectively. | Danfeng Ji Beidou Xi Jing Su Shouliang Huo Li He Hongliang Liu Queping Yang | 2013 | Journal of Environmental Sciences2013，25，9： | 2 |
| 17 | Enhanced treatment for cerebral ischemia-reperfusion injury of puerarin loading liposomes through neutrophils-mediated targeted delivery显示文摘The recovery of blood circulation following cerebral infarction-associated thrombolysis brings new damage to the brain,which is cerebral ischemia-reperfusion injury(CIRI).Inflammation is the main pathological mechanism of CIRI.The inflammatory response triggered by cerebral ischemia-reperfusion provides neutrophils with a special opportunity to facilitate drug delivery to the site of ischemic penumbra through the chemotaxis of inflammatory factors by neutrophils.Puerarin is an isoflavone derivative with a significant neuroprotective effect in vitro.But the blood-brain barrier(BBB)impedes its therapeutic efficacy on CIRI within the brain.Inspired by the pathological process,we have used neutrophils as carriers to enhance the BBB penetration of liposomes loaded with puerarin and improve the concentration of puerarin in the brain parenchyma in this study.These results showed that puerarin-containing liposomes were released in response to inflammatory conditions associated with brain injury to enhance the neuroprotection effect at the ischemic penumbra. | Wei Liu Haowei Lu Xiaoyong Rao Xiang Li Hongdan Lu Feifei Li Yan He Riyue Yu Rongsheng Zhong Yao Zhang Xiaojian Luo Hongliang Xin | 2021 | Nano Research2021，14，12： | 2 |
| 18 | Spatial distribution of arbuscular mycorrhizal fungi, glomalin and soil enzymes under the canopy of Astragalus adsurgens Pall. in the Mu Us sandland, China显示文摘 | Chunming Bai Xueli He Hongliang Tang Baoqin Shan Lili Zhao | 2009 | Soil Biology and Biochemistry2009，，： | 2 |
| 19 | High-metallic-phase-concentration MO1-xWxS2 nanosheets with expanded interlayers as efficient electrocatalysts显示文摘 | Qun He Yangyang Wan Hongliang Jiang Chuanqiang Wu Zhongti Sun Shuangming Chen Yu Zhou Haiping Chen Daobin Liu Yasir A. Haleem Binghui Ge Xiaojun Wu Li Song | 2018 | Nano Research2018，11，3： | 1 |
| 20 | Photocatalytic activity of shock-treated TiO2 powder显示文摘 | Liu Jianjun Yu Yingchun He Hongliang | 2000 | Mater Res Bull2000，35，： | 1 |
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